RGD DISEASE ONTOLOGY - ANNOTATIONS
RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term: Entamoebiasis
Accession: DOID:9008865
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Definition: Infection with amoebae of the genus ENTAMOEBA. Infection with E. histolytica causes DYSENTERY, AMEBIC and LIVER ABSCESS, AMEBIC.
Synonyms: exact_synonym: amoebiasis due to Entamoeba histolytica; entamoebiases
primary_id: MESH:C531613 ; MESH:D004749
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Ifng
interferon gamma
ISO IMP
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:16374615 PMID:29255076
RGD:14975099
NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
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Il10
interleukin 10
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16374615
NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
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Il1b
interleukin 1 beta
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16374615
NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
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Il2
interleukin 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16374615
NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108
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Il5
interleukin 5
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16374615
NCBI chr11:53,611,621...53,615,930
Ensembl chr11:53,611,621...53,615,933
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Il6
interleukin 6
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16374615
NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
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Nfkb1
nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
severity
IMP
RGD
PMID:20086086
RGD:40902842
NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308
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Tlr4
toll-like receptor 4
IMP
RGD
PMID:15910421
RGD:7241086
NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all