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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Respiratory Tract Infections
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Accession:DOID:9008680 term browser browse the term
Definition:Invasion of the host RESPIRATORY SYSTEM by microorganisms, usually leading to pathological processes or diseases.
Synonyms:exact_synonym: Respiratory Infection, Upper;   Respiratory Infections;   Respiratory Tract Infection;   Upper Respiratory Infections;   Upper Respiratory Tract Infections
 primary_id: MESH:D012141;   RDO:0000329


show annotations for term's descendants           Sort by:
Respiratory Tract Infections term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BDNF brain derived neurotrophic factor IEP protein:decreased expression:platelet, serum RGD PMID:17317133 RGD:4891069 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058 		JBrowse link
G CXCR3 C-X-C motif chemokine receptor 3 ISO RGD PMID:19039768 RGD:4892119 NCBI chr  X:71,615,919...71,618,511
Ensembl chr  X:71,615,916...71,618,511 		JBrowse link
G FBLN5 fibulin 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:12189163 NCBI chr14:91,869,411...91,947,694
Ensembl chr14:91,869,411...91,947,987 		JBrowse link
G HLA-G major histocompatibility complex, class I, G IAGP RGD PMID:19775370 RGD:5144114 NCBI chr 6:29,826,474...29,831,021
Ensembl chr 6:29,826,967...29,831,125 		JBrowse link
G IL13 interleukin 13 IEP Severe Acute Respiratory Syndrome RGD PMID:14633438 RGD:4145665 NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110 		JBrowse link
G IL16 interleukin 16 IEP protein:increased expression:serum RGD PMID:14633438 RGD:4145665 NCBI chr15:81,182,712...81,314,058
Ensembl chr15:81,159,575...81,314,058 		JBrowse link
G IL4 interleukin 4 IEP associated with Asthma RGD PMID:20573437 RGD:5128554 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G IL6R interleukin 6 receptor IAGP DNA:polymorphisms:promoter, exon:-183G>A (human) RGD PMID:20951753 RGD:5128631 NCBI chr 1:154,405,343...154,469,450
Ensembl chr 1:154,405,193...154,469,450 		JBrowse link
G IRF1 interferon regulatory factor 1 ISO RGD PMID:10497103 RGD:5128721 NCBI chr 5:132,481,609...132,490,773
Ensembl chr 5:132,440,440...132,508,719 		JBrowse link
G IRF3 interferon regulatory factor 3 ISO RGD PMID:17027894 RGD:5128795 NCBI chr19:49,659,572...49,665,857
Ensembl chr19:49,659,569...49,665,875 		JBrowse link
G LEPR leptin receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:17229951 NCBI chr 1:65,420,652...65,641,559
Ensembl chr 1:65,420,652...65,641,559 		JBrowse link
G MBL2 mannose binding lectin 2 susceptibility IEP
IAGP		 protein:decreased secretion:serum (human)
DNA:SNP:exon:p.G54D(rs1800450)(human)
DNA:polymorphisms:5' utr, exon:multiple (human)		 RGD PMID:19169708 PMID:15249448 PMID:19767106 RGD:4889453, RGD:8693755, RGD:4889439 NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784 		JBrowse link
G MX1 MX dynamin like GTPase 1 IEP protein:increased expression:blood (human) RGD PMID:25542463 RGD:126777677 NCBI chr21:41,420,558...41,459,214
Ensembl chr21:41,420,020...41,470,071 		JBrowse link
G RPGR retinitis pigmentosa GTPase regulator EXP CTD Direct Evidence: marker/mechanism CTD PMID:12920075 NCBI chr  X:38,269,163...38,327,509
Ensembl chr  X:38,269,163...38,327,544 		JBrowse link
G TNF tumor necrosis factor IEP Severe Acute Respiratory Syndrome; protein:increased expression:serum RGD PMID:14633438 RGD:4145665 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
allergic bronchopulmonary aspergillosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL17 C-C motif chemokine ligand 17 IEP associated with Cystic Fibrosis RGD PMID:17898016 RGD:4145612 NCBI chr16:57,396,093...57,416,063
Ensembl chr16:57,404,767...57,416,063 		JBrowse link
G CCR1 C-C motif chemokine receptor 1 ISO RGD PMID:15951834 RGD:5688155 NCBI chr 3:46,201,711...46,208,313
Ensembl chr 3:46,201,711...46,208,313 		JBrowse link
G CCR2 C-C motif chemokine receptor 2 ISO RGD PMID:10946288 RGD:8661731 NCBI chr 3:46,354,111...46,360,940
Ensembl chr 3:46,353,864...46,360,940 		JBrowse link
G CFTR CF transmembrane conductance regulator IAGP DNA:mutations: : RGD PMID:11243954 RGD:4140482 NCBI chr 7:117,480,025...117,668,665
Ensembl chr 7:117,287,120...117,715,971 		JBrowse link
G HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 susceptibility IAGP associated with cystic fibrosis; DNA:polymorphisms: :DQB1*06:02, DQB1*02:01(human) RGD PMID:23278646 RGD:36049760 NCBI chr 6:32,659,467...32,666,657
Ensembl chr 6:32,659,467...32,668,383 		JBrowse link
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 susceptibility IAGP associated with cystic fibrosis; DNA:polymorphisms: : RGD PMID:23278646 RGD:36049760 NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,577,902...32,589,848 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO RGD PMID:7743671 RGD:8547590 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615 		JBrowse link
G IL1A interleukin 1 alpha ISO RGD PMID:8699818 RGD:7794730 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493 		JBrowse link
G MBL2 mannose binding lectin 2 susceptibility IAGP Chronic Necrotizing Pulmonary Aspergillosis; DNA:missense mutation:exon:p.R52C (human)
DNA:SNP:intron:1011G>A(human)		 RGD PMID:11474427 PMID:16487239 RGD:4889577, RGD:8693711 NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784 		JBrowse link
G TLR9 toll like receptor 9 susceptibility ISO
IAGP		 DNA:SNP:promoter:g.-1237T>C (rs5743836) (human) RGD PMID:18936185 PMID:18275280 RGD:5130858, RGD:5130863 NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,225,645 		JBrowse link
G TNF tumor necrosis factor ISO RGD PMID:8699818 RGD:7794730 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A susceptibility IAGP DNA:snps:5' utr, exon:g.-609G>T rs4149570, g.36A>G rs767455 (human) RGD PMID:20646338 RGD:5131174 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114 		JBrowse link
allergic rhinitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 severity IAGP DNA:snp:exon:c.1236C>T (human) RGD PMID:24040855 RGD:8657076 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G ACE angiotensin I converting enzyme no_association IAGP DNA:deletion:intron:IVS16+1464-1751del (human) RGD PMID:15112973 RGD:8142345 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380 		JBrowse link
G BCL2 BCL2 apoptosis regulator ISO mRNA, protein:increased expression:nasal mucosa (rat) RGD PMID:15362690 RGD:11522724 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G CAT catalase EXP CTD Direct Evidence: marker/mechanism CTD PMID:29028686 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CCL11 C-C motif chemokine ligand 11 treatment ISO RGD PMID:23089405 RGD:7248414 NCBI chr17:34,285,742...34,288,334
Ensembl chr17:34,285,742...34,288,334 		JBrowse link
G CCL26 C-C motif chemokine ligand 26 IEP protein:increased expression:oronasal secretion (human) RGD PMID:23883806 RGD:7364793 NCBI chr 7:75,769,524...75,791,597
Ensembl chr 7:75,769,533...75,789,896 		JBrowse link
G CD40 CD40 molecule IEP protein:increased expression:lymphocyte RGD PMID:19086656 RGD:8547782 NCBI chr20:46,118,314...46,129,858
Ensembl chr20:46,118,271...46,129,863 		JBrowse link
G CD40LG CD40 ligand IEP protein:increased expression:lymphocyte RGD PMID:19086656 RGD:8547782 NCBI chr  X:136,648,158...136,660,390
Ensembl chr  X:136,648,158...136,660,390 		JBrowse link
G CLDN3 claudin 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:33441633 NCBI chr 7:73,768,997...73,770,270
Ensembl chr 7:73,768,997...73,770,270 		JBrowse link
G CLDN7 claudin 7 EXP CTD Direct Evidence: marker/mechanism CTD PMID:33441633 NCBI chr17:7,259,903...7,263,213
Ensembl chr17:7,259,903...7,263,983 		JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 treatment ISO RGD PMID:10436391 RGD:11344920 NCBI chr 2:203,867,771...203,873,965
Ensembl chr 2:203,853,888...203,873,965 		JBrowse link
G F2 coagulation factor II, thrombin IEP protein:increased expression:nasal mucus RGD PMID:21711961 RGD:5147783 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506 		JBrowse link
G FCGR3A Fc gamma receptor IIIa susceptibility IAGP DNA:polymorphism:exon:p.F158V(rs396991)(human) RGD PMID:18199088 RGD:5508449 NCBI chr 1:161,541,759...161,550,737
Ensembl chr 1:161,541,759...161,550,968 		JBrowse link
G GRIA1 glutamate ionotropic receptor AMPA type subunit 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:34624383 NCBI chr 5:153,489,615...153,813,869
Ensembl chr 5:153,489,615...153,813,869 		JBrowse link
G GRIA2 glutamate ionotropic receptor AMPA type subunit 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:34624383 NCBI chr 4:157,220,120...157,366,075
Ensembl chr 4:157,204,182...157,387,146 		JBrowse link
G HLA-G major histocompatibility complex, class I, G IEP RGD PMID:20487636 RGD:5144132 NCBI chr 6:29,826,474...29,831,021
Ensembl chr 6:29,826,967...29,831,125 		JBrowse link
G HRH1 histamine receptor H1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23333628 NCBI chr 3:11,137,238...11,263,557
Ensembl chr 3:11,137,093...11,263,557 		JBrowse link
G IFNG interferon gamma treatment IEP
EXP
ISO		 associated with Asthma
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:29871060 PMID:12787306 PMID:18510219 RGD:7829803, RGD:10755770 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IL10 interleukin 10 treatment IEP
ISO		 RGD PMID:23883806 PMID:23253209 RGD:7364793, RGD:7364818 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL13 interleukin 13 susceptibility
no_association		 IAGP
EXP		 DNA:SNP:promoter:-1512A>C (rs1881457) (human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphism:exon:c. 2044G>A (human)
DNA:missense mutation:cds:p.R130Q (rs20541) (human)
DNA:SNPs:promoter, cds:-1112C>T, p.R130Q (rs1800925, rs20541) (human)		 CTD
OMIM
RGD		 PMID:23996716 PMID:17091279 PMID:22852128 PMID:12928861 RGD:8549501, RGD:4152796, RGD:8549518, RGD:8549516 NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110 		JBrowse link
G IL13RA2 interleukin 13 receptor subunit alpha 2 IEP protein:increased expression:serum RGD PMID:21462799 RGD:8549521 NCBI chr  X:115,003,982...115,017,616
Ensembl chr  X:115,003,975...115,019,977 		JBrowse link
G IL17A interleukin 17A susceptibility IAGP
IEP		 DNA:snp:promoter:c.-444A>G (human)
mRNA:increased expression:peripheral blood mononuclear cell (human)		 RGD PMID:22507625 PMID:21535180 RGD:9068429, RGD:5147409 NCBI chr 6:52,186,375...52,190,638
Ensembl chr 6:52,186,375...52,190,638 		JBrowse link
G IL18 interleukin 18 severity
no_association		 IAGP DNA:SNP:promoter:-137G>C (rs187238) (human)
DNA:SNP:promoter:-140C>G (rs360721) (human)		 RGD PMID:22840759 PMID:22840759 RGD:8655914, RGD:8655914 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096 		JBrowse link
G IL1B interleukin 1 beta IEP protein:increased expression:nasal mucus RGD PMID:7750009 RGD:7401199 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL2 interleukin 2 ISO RGD PMID:12592663 RGD:8662963 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725 		JBrowse link
G IL4 interleukin 4 treatment IEP
ISO		 RGD PMID:9893928 PMID:24620662 PMID:8908280 PMID:14653048 RGD:7829796, RGD:11522769, RGD:7829827, RGD:7829802 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G IL5 interleukin 5 treatment ISO RGD PMID:23934070 PMID:24620662 RGD:11354976, RGD:11522769 NCBI chr 5:132,541,445...132,556,815
Ensembl chr 5:132,541,445...132,556,838 		JBrowse link
G ITGB2 integrin subunit beta 2 treatment ISO RGD PMID:12046991 RGD:9698435 NCBI chr21:44,885,953...44,928,815
Ensembl chr21:44,885,953...44,931,989 		JBrowse link
G MUC1 mucin 1, cell surface associated severity IEP
ISO		 mRNA,protein:decreased expression:nasal mucosa RGD PMID:31425778 PMID:31425778 PMID:31425778 RGD:127345100, RGD:127345100, RGD:127345100 NCBI chr 1:155,185,824...155,192,915
Ensembl chr 1:155,185,824...155,192,916 		JBrowse link
G MUC5AC mucin 5AC, oligomeric mucus/gel-forming ISO mRNA, protein:increased expression:nasal cavity epithelium RGD PMID:22972875 RGD:7364746 NCBI chr11:1,157,953...1,201,138
Ensembl chr11:1,157,953...1,201,138 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 IEP mRNA:increased expression:nasal mucosa (human) RGD PMID:23858718 RGD:8547523 NCBI chr16:50,693,606...50,733,075
Ensembl chr16:50,693,588...50,733,077 		JBrowse link
G OCLN occludin EXP CTD Direct Evidence: marker/mechanism CTD PMID:33441633 NCBI chr 5:69,492,547...69,558,104
Ensembl chr 5:69,492,292...69,558,104 		JBrowse link
G PON1 paraoxonase 1 severity IEP protein:decreased activity:plasma (human) RGD PMID:23406590 RGD:8547583 NCBI chr 7:95,297,676...95,324,532
Ensembl chr 7:95,297,676...95,324,532 		JBrowse link
G PRKG1 protein kinase cGMP-dependent 1 ISO protein:increased expression:nasal cavity epithelium RGD PMID:24012634 RGD:7775060 NCBI chr10:50,990,888...52,298,350
Ensembl chr10:50,990,888...52,298,423 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16979129 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G SCGB1A1 secretoglobin family 1A member 1 ISO mRNA:decreased expression:nasal mucosa, lung RGD PMID:17882576 RGD:5144135 NCBI chr11:62,419,033...62,423,195
Ensembl chr11:62,405,103...62,423,195 		JBrowse link
G SCGB3A2 secretoglobin family 3A member 2 susceptibility IAGP DNA:SNP: :rs7726552 (human) RGD PMID:21410962 RGD:5144225 NCBI chr 5:147,878,711...147,882,191
Ensembl chr 5:147,870,682...147,882,191 		JBrowse link
G SERPINE1 serpin family E member 1 ISO mRNA:increased expression:nasal mucosa (mouse) RGD PMID:21339035 RGD:8547809 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247 		JBrowse link
G TACR1 tachykinin receptor 1 ISO mRNA:increased expression:nasal mucosa RGD PMID:12768696 RGD:5147835 NCBI chr 2:75,046,463...75,199,520
Ensembl chr 2:75,046,463...75,199,520 		JBrowse link
G TGFB1 transforming growth factor beta 1 treatment ISO RGD PMID:31368266 RGD:14995445 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G TLR2 toll like receptor 2 severity IAGP
IEP
ISO		 DNA:polymorphism:cds:p.R753Q(human)
protein:increased expression:neutrophil:
mRNA:decreased expression:nasal mucosa:		 RGD PMID:22402138 PMID:22555057 PMID:18381801 PMID:18219831 RGD:7800732, RGD:8552993, RGD:8552972, RGD:7800742 NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,070...153,706,260 		JBrowse link
G TLR4 toll like receptor 4 severity
treatment
susceptibility
no_association		 IAGP
IEP
IDA		 DNA:polymorphism:cds:p.D299G(human)
protein:increased expression:nasal lavage,leukocyte, bone marrow:
protein:decreased expression:nasal mucosa:
DNA:SNP: :rs1927911(human)
DNA:polymorphism: :4216G>C(human)		 RGD PMID:22402138 PMID:22555057 PMID:22577387 PMID:17069098 PMID:23639307 More... RGD:7800732, RGD:8552993, RGD:7800740, RGD:7800738, RGD:7800736, RGD:4145354 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G TLR9 toll like receptor 9 IEP protein:decreased expression:nasal mucosa: RGD PMID:22577387 RGD:7800740 NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,225,645 		JBrowse link
Allergic Rhinoconjunctivitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 treatment IAGP associated with Eosinophilic Esophagitis; DNA:polymorphisms:: RGD PMID:26416193 RGD:11352743 NCBI chr10:94,762,681...94,855,547
Ensembl chr10:94,762,681...94,855,547 		JBrowse link
G IL3 interleukin 3 susceptibility IAGP DNA:SNP: :rs40401(human) RGD PMID:23953855 RGD:13506915 NCBI chr 5:132,060,655...132,063,204
Ensembl chr 5:132,060,655...132,063,204 		JBrowse link
aspergillosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGER advanced glycosylation end-product specific receptor IAGP DNA:SNP:promoter:-374T>A (human) RGD PMID:22114731 RGD:8695981 NCBI chr 6:32,180,969...32,184,253
Ensembl chr 6:32,180,968...32,184,322 		JBrowse link
G CCL19 C-C motif chemokine ligand 19 ISO associated with Neutropenia;mRNA:increased expression:lung RGD PMID:19783686 RGD:5130908 NCBI chr 9:34,689,570...34,691,276
Ensembl chr 9:34,689,570...34,691,276 		JBrowse link
G CCR7 C-C motif chemokine receptor 7 ISO associated with Neutropenia RGD PMID:19783686 RGD:5130908 NCBI chr17:40,553,769...40,565,472
Ensembl chr17:40,553,769...40,565,472 		JBrowse link
G CD209 CD209 molecule IMP RGD PMID:21381282 RGD:5131183 NCBI chr19:7,739,993...7,747,534
Ensembl chr19:7,739,993...7,747,564 		JBrowse link
G CFTR CF transmembrane conductance regulator severity ISO RGD PMID:22135344 RGD:35673332 NCBI chr 7:117,480,025...117,668,665
Ensembl chr 7:117,287,120...117,715,971 		JBrowse link
G CLEC1A C-type lectin domain family 1 member A susceptibility IAGP
EXP		 ClinVar Annotator: match by term: Aspergillosis, susceptibility to
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
OMIM		 PMID:29489751 NCBI chr12:10,069,554...10,098,985
Ensembl chr12:10,069,554...10,111,627 		JBrowse link
G CLEC7A C-type lectin domain containing 7A susceptibility IAGP
EXP		 ClinVar Annotator: match by term: Aspergillosis, susceptibility to
CTD Direct Evidence: marker/mechanism		 ClinVar
OMIM
CTD		 PMID:19864674 PMID:20807886 PMID:24033266 PMID:25741868 NCBI chr12:10,116,777...10,130,304
Ensembl chr12:10,116,777...10,130,258 		JBrowse link
G CRP C-reactive protein treatment IEP RGD PMID:20879853 RGD:9495929 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589 		JBrowse link
G IL15 interleukin 15 IAGP DNA:polymorphism (human) RGD PMID:16893395 RGD:4981337 NCBI chr 4:141,636,583...141,733,987
Ensembl chr 4:141,636,583...141,733,987 		JBrowse link
G MBL1P mannose binding lectin 1, pseudogene susceptibility ISO RGD PMID:20064561 RGD:8694071 NCBI chr10:79,920,178...79,923,119
Ensembl chr10:79,920,327...79,923,032
Ensembl chr10:79,920,327...79,923,032 		JBrowse link
G MBL2 mannose binding lectin 2 susceptibility ISO RGD PMID:20064561 RGD:8694071 NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784 		JBrowse link
G S100B S100 calcium binding protein B IAGP DNA:SNP: :427C>T (human) RGD PMID:22114731 RGD:8695981 NCBI chr21:46,598,604...46,605,082
Ensembl chr21:46,598,604...46,605,208 		JBrowse link
G TLR1 toll like receptor 1 susceptibility IAGP DNA:SNPs: :p.R80T, p.N248S (human) RGD PMID:16461792 RGD:4889535 NCBI chr 4:38,787,569...38,805,644
Ensembl chr 4:38,790,677...38,856,817 		JBrowse link
G TLR2 toll like receptor 2 ISO mRNA:increased expression:lung RGD PMID:19781388 RGD:4145322 NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,070...153,706,260 		JBrowse link
G TLR6 toll like receptor 6 susceptibility IAGP DNA:SNP: :p.S249P (human) RGD PMID:16461792 RGD:4889535 NCBI chr 4:38,822,897...38,868,390
Ensembl chr 4:38,822,897...38,856,817 		JBrowse link
aspiration pneumonia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme IMP associated with Cerebrovascular Accident RGD PMID:14990394 RGD:4140926 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380 		JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 ISO RGD PMID:19515386 RGD:4891456 NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308 		JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 ISO RGD PMID:19515386 RGD:4891456 NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196 		JBrowse link
G EDN1 endothelin 1 ISO protein:increased secretion:plasma (rat) RGD PMID:19262391 RGD:4145069 NCBI chr 6:12,230,516...12,297,194
Ensembl chr 6:12,290,361...12,297,194 		JBrowse link
G IL1A interleukin 1 alpha ISO protein:increased expression:Bronchoalveolar Lavage Fluid RGD PMID:18042282 RGD:4142854 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493 		JBrowse link
G NOS2 nitric oxide synthase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15607125 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G TNF tumor necrosis factor ISO protein:increased expression:Bronchoalveolar Lavage Fluid RGD PMID:18042282 RGD:4142854 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
Bacterial Lung Diseases term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CXCL8 C-X-C motif chemokine ligand 8 severity IEP protein:increased expression:nasal mucus (human) RGD PMID:24211414 RGD:40925940 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G MARCO macrophage receptor with collagenous structure disease_progression ISO association with Cryptococcal neoformans infection. RGD PMID:28298522 RGD:41412191 NCBI chr 2:118,942,194...118,994,660
Ensembl chr 2:118,942,194...118,994,660 		JBrowse link
bacterial pneumonia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC1 ATP binding cassette subfamily C member 1 (ABCC1 blood group) ISO RGD PMID:11238654 RGD:5128828 NCBI chr16:15,949,143...16,143,053
Ensembl chr16:15,949,138...16,143,257 		JBrowse link
G ACE2 angiotensin converting enzyme 2 ISO associated with Pseudomonas Infections;mRNA, protein:altered expression, altered activity:lung (mouse) RGD PMID:31645418 RGD:40818279 NCBI chr  X:15,518,197...15,607,211
Ensembl chr  X:15,494,566...15,607,236 		JBrowse link
G AGER advanced glycosylation end-product specific receptor severity ISO RGD PMID:21629785 RGD:6767559 NCBI chr 6:32,180,969...32,184,253
Ensembl chr 6:32,180,968...32,184,322 		JBrowse link
G C3 complement C3 ISO RGD PMID:16014897 RGD:5129508 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562 		JBrowse link
G C3AR1 complement C3a receptor 1 ISO RGD PMID:16461429 RGD:5129690 NCBI chr12:8,056,844...8,066,359
Ensembl chr12:8,056,844...8,066,359 		JBrowse link
G C5 complement C5 ISO RGD PMID:17975174 RGD:5129707 NCBI chr 9:120,952,335...121,074,865
Ensembl chr 9:120,932,987...121,075,195 		JBrowse link
G CAT catalase ISO RGD PMID:19842849 RGD:5130748 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CCL19 C-C motif chemokine ligand 19 ISO mRNA, protein:increased expression:lung RGD PMID:20176793 RGD:5130918 NCBI chr 9:34,689,570...34,691,276
Ensembl chr 9:34,689,570...34,691,276 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 ISO RGD PMID:20042590 RGD:4891443 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CCL4 C-C motif chemokine ligand 4 ISO RGD PMID:20483921 RGD:5130905 NCBI chr17:36,103,827...36,105,614
Ensembl chr17:36,103,827...36,105,621 		JBrowse link
G CCR2 C-C motif chemokine receptor 2 ISO RGD PMID:20042590 RGD:4891443 NCBI chr 3:46,354,111...46,360,940
Ensembl chr 3:46,353,864...46,360,940 		JBrowse link
G CCR7 C-C motif chemokine receptor 7 ISO RGD PMID:20176793 RGD:5130918 NCBI chr17:40,553,769...40,565,472
Ensembl chr17:40,553,769...40,565,472 		JBrowse link
G CD14 CD14 molecule ISO RGD PMID:16210672 RGD:4144197 NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,700 		JBrowse link
G CD40 CD40 molecule ISO RGD PMID:20102413 RGD:5132268 NCBI chr20:46,118,314...46,129,858
Ensembl chr20:46,118,271...46,129,863 		JBrowse link
G CD80 CD80 molecule ISO RGD PMID:20949109 RGD:4892562 NCBI chr 3:119,524,293...119,559,614
Ensembl chr 3:119,524,293...119,559,614 		JBrowse link
G CHUK component of inhibitor of nuclear factor kappa B kinase complex ISO RGD PMID:18643924 RGD:5133701 NCBI chr10:100,186,319...100,229,596
Ensembl chr10:100,188,300...100,229,596 		JBrowse link
G CSF3 colony stimulating factor 3 disease_progression
treatment		 IEP
IDA		 associated with Peritonitis; RGD PMID:21373266 PMID:12352049 RGD:5133733, RGD:11039437 NCBI chr17:40,015,440...40,017,813
Ensembl chr17:40,015,361...40,017,813 		JBrowse link
G CSF3R colony stimulating factor 3 receptor disease_progression ISO RGD PMID:17185469 RGD:5133739 NCBI chr 1:36,466,043...36,483,314
Ensembl chr 1:36,466,043...36,483,278 		JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 ISO RGD PMID:21723409 PMID:11052817 RGD:5135062, RGD:5135234 NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308 		JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 severity ISO RGD PMID:16299319 PMID:15618188 RGD:5135458, RGD:5135459 NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497 		JBrowse link
G CXCL11 C-X-C motif chemokine ligand 11 ISO RGD PMID:15618188 RGD:5135459 NCBI chr 4:76,033,682...76,036,070
Ensembl chr 4:76,033,682...76,041,415 		JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 severity ISO RGD PMID:19239431 PMID:11052817 PMID:21723409 RGD:5135065, RGD:5135234, RGD:5135062 NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196 		JBrowse link
G CXCL3 C-X-C motif chemokine ligand 3 ISO RGD PMID:11052817 RGD:5135234 NCBI chr 4:74,036,589...74,038,689
Ensembl chr 4:74,036,589...74,038,807 		JBrowse link
G CXCL5 C-X-C motif chemokine ligand 5 ISO RGD PMID:19846873 RGD:4145490 NCBI chr 4:73,995,642...73,998,677
Ensembl chr 4:73,995,642...73,998,677 		JBrowse link
G CXCL6 C-X-C motif chemokine ligand 6 ISO RGD PMID:19846873 RGD:4145490 NCBI chr 4:73,836,678...73,838,760
Ensembl chr 4:73,836,640...73,849,064 		JBrowse link
G CXCL9 C-X-C motif chemokine ligand 9 ISO RGD PMID:15618188 RGD:5135459 NCBI chr 4:76,001,275...76,007,509
Ensembl chr 4:76,001,275...76,007,509 		JBrowse link
G CXCR3 C-X-C motif chemokine receptor 3 ISO RGD PMID:15618188 RGD:5135459 NCBI chr  X:71,615,919...71,618,511
Ensembl chr  X:71,615,916...71,618,511 		JBrowse link
G CYP2J2 cytochrome P450 family 2 subfamily J member 2 ISO protein:decreased expression:lung RGD PMID:14766666 RGD:1625385 NCBI chr 1:59,893,308...59,969,212
Ensembl chr 1:59,893,308...59,926,773 		JBrowse link
G DEFB4A defensin beta 4A IEP protein:increased expression:plasma RGD PMID:10213993 RGD:4892266 NCBI chr 8:7,894,677...7,896,716
Ensembl chr 8:7,894,677...7,896,716
Ensembl chr 8:7,894,677...7,896,716 		JBrowse link
G F2 coagulation factor II, thrombin ISO RGD PMID:21897338 RGD:6893486 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506 		JBrowse link
G FCGR2A Fc gamma receptor IIa ISO RGD PMID:17975174 RGD:5129707 NCBI chr 1:161,505,457...161,524,048
Ensembl chr 1:161,505,430...161,524,013 		JBrowse link
G FOXP3 forkhead box P3 severity ISO RGD PMID:25398094 RGD:38501102 NCBI chr  X:49,250,438...49,264,710
Ensembl chr  X:49,250,438...49,264,800 		JBrowse link
G GP1BA glycoprotein Ib platelet subunit alpha exacerbates ISO associated with Escherichia Coli Infections RGD PMID:27845343 RGD:42722624 NCBI chr17:4,932,277...4,935,023
Ensembl chr17:4,932,277...4,935,023 		JBrowse link
G GRK2 G protein-coupled receptor kinase 2 IEP mRNA:decreased expression:polymorphonuclear leukocyte RGD PMID:24465168 RGD:126848796 NCBI chr11:67,266,473...67,286,556
Ensembl chr11:67,266,473...67,286,556 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO protein:increased expression:lung (mouse) RGD PMID:19846873 RGD:4145490 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615 		JBrowse link
G IFNAR1 interferon alpha and beta receptor subunit 1 severity ISO RGD PMID:19487810 PMID:19487810 RGD:5490274, RGD:5490274 NCBI chr21:33,324,395...33,359,864
Ensembl chr21:33,324,387...33,359,864 		JBrowse link
G IFNG interferon gamma severity ISO RGD PMID:25398094 RGD:38501102 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IL10 interleukin 10 severity ISO RGD PMID:25398094 RGD:38501102 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL15 interleukin 15 ISO RGD PMID:17911627 RGD:5000754 NCBI chr 4:141,636,583...141,733,987
Ensembl chr 4:141,636,583...141,733,987 		JBrowse link
G IL17A interleukin 17A severity ISO RGD PMID:18802100 PMID:25398094 RGD:4889153, RGD:38501102 NCBI chr 6:52,186,375...52,190,638
Ensembl chr 6:52,186,375...52,190,638 		JBrowse link
G IL18 interleukin 18 ISO RGD PMID:17664259 RGD:4889913 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096 		JBrowse link
G IL1B interleukin 1 beta severity
treatment		 ISO
IDA		 associated with Agranulocytosis RGD PMID:18596024 PMID:25398094 PMID:7546648 RGD:4143205, RGD:38501102, RGD:10755357 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL1RL1 interleukin 1 receptor like 1 treatment ISO associated with Sepsis
associated with Acinetobacter infectious disease		 RGD PMID:20959556 PMID:29508184 RGD:5144223, RGD:40818077 NCBI chr 2:102,311,563...102,352,356
Ensembl chr 2:102,311,502...102,352,037 		JBrowse link
G IL1RN interleukin 1 receptor antagonist ISO RGD PMID:18322242 PMID:18596024 RGD:4143206, RGD:4143205 NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016 		JBrowse link
G IL22 interleukin 22 ISO RGD PMID:21178015 RGD:5147404 NCBI chr12:68,248,242...68,253,604
Ensembl chr12:68,248,242...68,253,604 		JBrowse link
G IL6 interleukin 6 severity ISO RGD PMID:25398094 RGD:38501102 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G IRAK3 interleukin 1 receptor associated kinase 3 ISO RGD PMID:28120642 PMID:20439918 RGD:34888234, RGD:36049799 NCBI chr12:66,189,214...66,254,622
Ensembl chr12:66,189,195...66,254,622 		JBrowse link
G IRF1 interferon regulatory factor 1 ISO RGD PMID:11854220 RGD:5128725 NCBI chr 5:132,481,609...132,490,773
Ensembl chr 5:132,440,440...132,508,719 		JBrowse link
G IRF3 interferon regulatory factor 3 ISO RGD PMID:20720199 RGD:4891951 NCBI chr19:49,659,572...49,665,857
Ensembl chr19:49,659,569...49,665,875 		JBrowse link
G ITGB3 integrin subunit beta 3 ISO protein:increased expression:lung, neutrophil RGD PMID:15114484 RGD:4993468 NCBI chr17:47,253,827...47,313,743
Ensembl chr17:47,253,827...47,313,743 		JBrowse link
G LEP leptin ISO RGD PMID:11937559 RGD:5128871 NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 severity ISO associated with Escherichia Coli Infections RGD PMID:22514650 RGD:150340681 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360 		JBrowse link
G MBL2 mannose binding lectin 2 IAGP Legionella Pneumonia; DNA:mutations:5' utr, exon:multiple (human) RGD PMID:18641104 RGD:4889477 NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784 		JBrowse link
G MC1R melanocortin 1 receptor ISO RGD PMID:18304533 RGD:5687324 NCBI chr16:89,918,862...89,920,972
Ensembl chr16:89,912,119...89,920,973 		JBrowse link
G MMP9 matrix metallopeptidase 9 ISO
IEP		 protein:increased expression:bronchoalveolar lavage fluid RGD PMID:17202364 PMID:19535150 RGD:5130727, RGD:5129533 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MPO myeloperoxidase IEP protein:increased activity:bronchoalveolar lavage Fluid: RGD PMID:11269653 RGD:5130992 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935 		JBrowse link
G NOD1 nucleotide binding oligomerization domain containing 1 ISO RGD PMID:19360122 RGD:5131449 NCBI chr 7:30,424,527...30,478,784
Ensembl chr 7:30,424,527...30,478,784 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 ISO RGD PMID:19360122 RGD:5131449 NCBI chr16:50,693,606...50,733,075
Ensembl chr16:50,693,588...50,733,077 		JBrowse link
G PDPN podoplanin ISO protein:increased expression:lung RGD PMID:7864138 RGD:2292375 NCBI chr 1:13,583,757...13,617,957
Ensembl chr 1:13,583,465...13,617,957 		JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 ISO protein:decreased expression:lung RGD PMID:12524254 RGD:724645 NCBI chr17:64,319,415...64,390,860
Ensembl chr17:64,319,415...64,413,776 		JBrowse link
G PGF placental growth factor ISO protein:increased expression:plasma RGD PMID:16702604 RGD:6483601 NCBI chr14:74,941,830...74,955,764
Ensembl chr14:74,941,834...74,955,626 		JBrowse link
G PTEN phosphatase and tensin homolog ameliorates ISO myeloid knockout RGD PMID:21527775 RGD:127285594 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930 		JBrowse link
G RIPK3 receptor interacting serine/threonine kinase 3 ameliorates ISO RGD PMID:28387756 RGD:127229944 NCBI chr14:24,336,025...24,339,991
Ensembl chr14:24,336,025...24,340,022 		JBrowse link
G RORC RAR related orphan receptor C severity ISO RGD PMID:25398094 RGD:38501102 NCBI chr 1:151,806,071...151,831,802
Ensembl chr 1:151,806,071...151,831,845 		JBrowse link
G SERPINE1 serpin family E member 1 severity ISO RGD PMID:17032919 RGD:4144840 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247 		JBrowse link
G SFTPA1 surfactant protein A1 ISO protein:increased expression:lung RGD PMID:12169586 RGD:4143464 NCBI chr10:79,610,939...79,615,455
Ensembl chr10:79,610,939...79,615,455 		JBrowse link
G SFTPB surfactant protein B IEP
ISO		 associated with Cystic Fibrosis;protein:increased expression:lung RGD PMID:15271694 PMID:12169586 RGD:4143403, RGD:4143464 NCBI chr 2:85,657,307...85,668,741
Ensembl chr 2:85,657,314...85,668,741 		JBrowse link
G SFTPC surfactant protein C ISO RGD PMID:18566429 PMID:12169586 RGD:4144114, RGD:4143464 NCBI chr 8:22,157,383...22,164,479
Ensembl chr 8:22,156,913...22,164,479 		JBrowse link
G SFTPD surfactant protein D ISO
IEP		 protein:increased expression:lung
associated with Cystic Fibrosis;protein:decreased expression:lung		 RGD PMID:12169586 PMID:15271694 RGD:4143464, RGD:4143403 NCBI chr10:79,937,740...79,982,383
Ensembl chr10:79,937,467...79,982,614 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 ISO RGD PMID:18192501 RGD:6892945 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568 		JBrowse link
G TGFB1 transforming growth factor beta 1 severity ISO RGD PMID:25398094 RGD:38501102 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G TLR2 toll like receptor 2 ISO RGD PMID:18768871 PMID:19844782 RGD:4145337, RGD:4889533 NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,070...153,706,260 		JBrowse link
G TLR4 toll like receptor 4 ISO RGD PMID:20650991 PMID:16210672 RGD:4144172, RGD:4144197 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G TLR5 toll like receptor 5 ISO RGD PMID:19801452 RGD:5129503 NCBI chr 1:223,109,404...223,143,248
Ensembl chr 1:223,109,404...223,143,248 		JBrowse link
G TLR6 toll like receptor 6 ISO RGD PMID:19844782 RGD:4889533 NCBI chr 4:38,822,897...38,868,390
Ensembl chr 4:38,822,897...38,856,817 		JBrowse link
G TLR9 toll like receptor 9 ISO RGD PMID:20360853 RGD:5130719 NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,225,645 		JBrowse link
G TNF tumor necrosis factor disease_progression
treatment
severity		 IEP
IDA
ISO		 associated with Agranulocytosis RGD PMID:10650487 PMID:7546648 PMID:9310939 PMID:12958055 RGD:4143476, RGD:10755357, RGD:10450564, RGD:10449451 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A ISO protein:increased expression:serum (mouse) RGD PMID:19842848 RGD:5131429 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114 		JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B ISO protein:increased expression:serum (mouse) RGD PMID:19842848 RGD:5131429 NCBI chr 1:12,166,991...12,209,220
Ensembl chr 1:12,166,991...12,209,228 		JBrowse link
G TREM1 triggering receptor expressed on myeloid cells 1 severity
ameliorates		 IEP
ISO		 RGD PMID:24465168 PMID:16960786 PMID:22996209 RGD:126848796, RGD:127229902, RGD:126925987 NCBI chr 6:41,267,385...41,286,682
Ensembl chr 6:41,267,926...41,286,682 		JBrowse link
G ZC3H12A zinc finger CCCH-type containing 12A ISO associated with Pseudomonas Infections RGD PMID:29695841 RGD:39938967 NCBI chr 1:37,474,580...37,484,377
Ensembl chr 1:37,474,580...37,484,377 		JBrowse link
bronchiolitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRB2 adrenoceptor beta 2 IDA RGD PMID:17687719 RGD:4145098 NCBI chr 5:148,826,611...148,828,623
Ensembl chr 5:148,826,611...148,828,623 		JBrowse link
G CCL11 C-C motif chemokine ligand 11 severity IEP
ISO		 protein:increased expression:nasal mucus
associated with Respiratory Syncytial Virus Infections		 RGD PMID:17297249 PMID:15681407 RGD:4145460, RGD:4145415 NCBI chr17:34,285,742...34,288,334
Ensembl chr17:34,285,742...34,288,334 		JBrowse link
G CD40 CD40 molecule IEP RGD PMID:19470255 RGD:5132271 NCBI chr20:46,118,314...46,129,858
Ensembl chr20:46,118,271...46,129,863 		JBrowse link
G CD86 CD86 molecule ISO protein:decreased expression:myeloid dendritic cell (mouse) RGD PMID:20046053 RGD:4892291 NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139 		JBrowse link
G CRP C-reactive protein severity IEP RGD PMID:21284715 RGD:5131282 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589 		JBrowse link
G CYSLTR1 cysteinyl leukotriene receptor 1 ISO associated with Pneumovirus Infections RGD PMID:16337014 RGD:4843953 NCBI chr  X:78,271,468...78,327,611
Ensembl chr  X:78,271,468...78,327,691 		JBrowse link
G IL17A interleukin 17A susceptibility IAGP DNA:SNP:promoter:rs2275913 (human) RGD PMID:20437253 RGD:4889139 NCBI chr 6:52,186,375...52,190,638
Ensembl chr 6:52,186,375...52,190,638 		JBrowse link
G IL1B interleukin 1 beta IEP protein:increased expression:lung RGD PMID:8608647 RGD:4143192 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL1RN interleukin 1 receptor antagonist IEP protein:increased expression:lung RGD PMID:8608647 RGD:4143192 NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016 		JBrowse link
G MUC5B mucin 5B, oligomeric mucus/gel-forming IAGP DNA:polymorphisms:promoter:rs885454,rs17235353, rs7115457 (human) RGD PMID:15709052 RGD:7349353 NCBI chr11:1,223,066...1,262,172
Ensembl chr11:1,223,066...1,262,172 		JBrowse link
bronchiolitis obliterans term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme ISO RGD PMID:17097496 RGD:4140933 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380 		JBrowse link
G ADORA2A adenosine A2a receptor ISO RGD PMID:19766783 RGD:4890362 NCBI chr22:24,423,597...24,442,357
Ensembl chr22:24,417,879...24,442,357 		JBrowse link
G CCL17 C-C motif chemokine ligand 17 IEP RGD PMID:18785972 RGD:4145604 NCBI chr16:57,396,093...57,416,063
Ensembl chr16:57,404,767...57,416,063 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 ISO RGD PMID:14611812 RGD:2307195 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CCL22 C-C motif chemokine ligand 22 IEP RGD PMID:20628341 RGD:4891471 NCBI chr16:57,357,909...57,366,189
Ensembl chr16:57,358,783...57,366,189 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 ISO mRNA:increased expression:lung (rat) RGD PMID:19840961 PMID:14611812 RGD:4889978, RGD:2307195 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793 		JBrowse link
G CCL7 C-C motif chemokine ligand 7 ISO protein:increased expression:bronchoalveolar Lavage fluid RGD PMID:22215510 RGD:6483763 NCBI chr17:34,270,221...34,272,242
Ensembl chr17:34,270,221...34,272,242 		JBrowse link
G CCR2 C-C motif chemokine receptor 2 ISO mRNA:increased expression:trachea: RGD PMID:11518728 RGD:4145124 NCBI chr 3:46,354,111...46,360,940
Ensembl chr 3:46,353,864...46,360,940 		JBrowse link
G CD86 CD86 molecule ISO RGD PMID:11266944 RGD:2307206 NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139 		JBrowse link
G CSF2 colony stimulating factor 2 ISO associated with Respiratory Aspiration;protein:increased expression:serum RGD PMID:18557728 RGD:2317286 NCBI chr 5:132,073,789...132,076,170
Ensembl chr 5:132,073,789...132,076,170 		JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 ISO
IEP		 protein:increased expression:respiratory system fluid/secretion RGD PMID:16709871 PMID:12097412 PMID:12097412 RGD:5135441, RGD:5135451, RGD:5135451 NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497 		JBrowse link
G CXCL11 C-X-C motif chemokine ligand 11 ISO
IEP		 protein:increased expression:respiratory system fluid/secretion RGD PMID:12097412 PMID:12097412 RGD:5135451, RGD:5135451 NCBI chr 4:76,033,682...76,036,070
Ensembl chr 4:76,033,682...76,041,415 		JBrowse link
G CXCL9 C-X-C motif chemokine ligand 9 ISO
IEP		 protein:increased expression:respiratory system fluid/secretion RGD PMID:16709871 PMID:12097412 PMID:12097412 RGD:5135441, RGD:5135451, RGD:5135451 NCBI chr 4:76,001,275...76,007,509
Ensembl chr 4:76,001,275...76,007,509 		JBrowse link
G CXCR3 C-X-C motif chemokine receptor 3 ISO RGD PMID:16709871 PMID:12097412 RGD:5135441, RGD:5135451 NCBI chr  X:71,615,919...71,618,511
Ensembl chr  X:71,615,916...71,618,511 		JBrowse link
G EDN1 endothelin 1 IMP human gene in a rat model RGD PMID:9595474 RGD:8662402 NCBI chr 6:12,230,516...12,297,194
Ensembl chr 6:12,290,361...12,297,194 		JBrowse link
G FOXP3 forkhead box P3 ISO mRNA:increased expression:lung RGD PMID:19840961 RGD:4889978 NCBI chr  X:49,250,438...49,264,710
Ensembl chr  X:49,250,438...49,264,800 		JBrowse link
G GZMB granzyme B IEP RGD PMID:19737140 RGD:5135518 NCBI chr14:24,630,954...24,634,190
Ensembl chr14:24,630,954...24,634,267 		JBrowse link
G HMOX1 heme oxygenase 1 ISO RGD PMID:12973103 RGD:4145412 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G IFNG interferon gamma EXP CTD Direct Evidence: therapeutic CTD PMID:16137903 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IL13 interleukin 13 ISO
IEP		 protein:increased expression:bronchoalveolar lavage fluid RGD PMID:17182591 PMID:17182591 RGD:4146242, RGD:4146242 NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110 		JBrowse link
G IL13RA1 interleukin 13 receptor subunit alpha 1 ISO RGD PMID:17182591 RGD:4146242 NCBI chr  X:118,727,606...118,805,228
Ensembl chr  X:118,727,133...118,794,535 		JBrowse link
G IL13RA2 interleukin 13 receptor subunit alpha 2 ISO RGD PMID:17182591 RGD:4146242 NCBI chr  X:115,003,982...115,017,616
Ensembl chr  X:115,003,975...115,019,977 		JBrowse link
G IL17A interleukin 17A ISO mRNA:increased expression:trachea RGD PMID:20393404 RGD:4143277 NCBI chr 6:52,186,375...52,190,638
Ensembl chr 6:52,186,375...52,190,638 		JBrowse link
G IL1RN interleukin 1 receptor antagonist IEP protein:increased expression:lung RGD PMID:11889437 RGD:4143176 NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016 		JBrowse link
G IL4 interleukin 4 ISO protein:increased expression:serum RGD PMID:18557728 RGD:2317286 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G IL6 interleukin 6 ISO RGD PMID:20393404 RGD:4143277 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G MBL2 mannose binding lectin 2 resistance IAGP DNA:transversion:5' utr:-290C>G rs7096206 (human) RGD PMID:19104434 RGD:4889456 NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784 		JBrowse link
G MMP9 matrix metallopeptidase 9 IEP protein:increased expression, increased activity:bronchoalveolar lavage fluid RGD PMID:20417130 RGD:5130759 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MUC1 mucin 1, cell surface associated IEP protein:increased expression:serum RGD PMID:16969297 RGD:5131273 NCBI chr 1:155,185,824...155,192,915
Ensembl chr 1:155,185,824...155,192,916 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 IAGP RGD PMID:18158963 RGD:5131450 NCBI chr16:50,693,606...50,733,075
Ensembl chr16:50,693,588...50,733,077 		JBrowse link
G NOS2 nitric oxide synthase 2 IEP associated with lung transplantation; protein:increased expression:lung RGD PMID:11112135 RGD:4892082 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NOS3 nitric oxide synthase 3 ISO protein:increased expression:lung RGD PMID:15136885 RGD:4892068 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588 		JBrowse link
G SCGB1A1 secretoglobin family 1A member 1 IEP associated with lung transplantation; protein:decreased expression:serum,bronchoalveolar lavage RGD PMID:11981419 RGD:5147386 NCBI chr11:62,419,033...62,423,195
Ensembl chr11:62,405,103...62,423,195 		JBrowse link
G SFTPD surfactant protein D IEP RGD PMID:18347569 RGD:4143500 NCBI chr10:79,937,740...79,982,383
Ensembl chr10:79,937,467...79,982,614 		JBrowse link
G TLR9 toll like receptor 9 IAGP DNA:SNPs:promoter, 3' utr:g.-1485C>T (rs187084), rs352162 (human) RGD PMID:20227302 RGD:5130722 NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,225,645 		JBrowse link
bronchitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 IAGP DNA:polymorphism (human) RGD PMID:14593914 RGD:4889126 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G EGR1 early growth response 1 ISO RGD PMID:17384085 RGD:5132266 NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303 		JBrowse link
G HDAC2 histone deacetylase 2 treatment ISO RGD PMID:22708526 RGD:9590258 NCBI chr 6:113,933,028...113,971,148
Ensembl chr 6:113,933,028...114,011,308 		JBrowse link
G IFNG interferon gamma resistance ISO RGD PMID:20953328 RGD:4145525 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
bronchopneumonia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL5 C-C motif chemokine ligand 5 IEP protein:increased secretion:serum (human) RGD PMID:20350425 RGD:4892019 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793 		JBrowse link
G CXCR2 C-X-C motif chemokine receptor 2 disease_progression ISO associated with Plague RGD PMID:21356370 RGD:5134954 NCBI chr 2:218,125,294...218,137,251
Ensembl chr 2:218,125,289...218,137,251 		JBrowse link
G MBL2 mannose binding lectin 2 IEP associated with Down Syndrome; protein:decreased secretion:serum (human) RGD PMID:19804807 RGD:4889483 NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784 		JBrowse link
Chlamydia pneumonia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD274 CD274 molecule ISO mRNA:increased expression:lung RGD PMID:26378990 RGD:41412180 NCBI chr 9:5,450,542...5,470,554
Ensembl chr 9:5,450,503...5,470,566 		JBrowse link
G PDCD1 programmed cell death 1 ISO mRNA:increased expression:lung RGD PMID:26378990 RGD:41412180 NCBI chr 2:241,849,884...241,858,894
Ensembl chr 2:241,849,884...241,858,894 		JBrowse link
G PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta severity ISO RGD PMID:29893841 RGD:40890270 NCBI chr 1:9,627,258...9,729,114
Ensembl chr 1:9,629,889...9,729,114 		JBrowse link
Chronic Bronchitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL11 C-C motif chemokine ligand 11 IEP RGD PMID:11991282 RGD:4145442 NCBI chr17:34,285,742...34,288,334
Ensembl chr17:34,285,742...34,288,334 		JBrowse link
G CFTR CF transmembrane conductance regulator susceptibility IAGP associated with pulmonary disease chronic obstructive; DNA:missense mutation:exon:p.R75Q(human)
DNA:deletion: :F508del(human)		 RGD PMID:15463907 PMID:10767489 RGD:4140475, RGD:4140484 NCBI chr 7:117,480,025...117,668,665
Ensembl chr 7:117,287,120...117,715,971 		JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 IAGP DNA:SNPs: :multiple (human) RGD PMID:19386687 RGD:4891509 NCBI chr 2:203,867,771...203,873,965
Ensembl chr 2:203,853,888...203,873,965 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 susceptibility IAGP DNA:polymorphism (human) RGD PMID:15928955 RGD:4142512 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 IAGP DNA:polymorphism (human) RGD PMID:14593914 RGD:4889126 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220 		JBrowse link
G EDN1 endothelin 1 ISO Chronic Allergic Airway Inflammation; protein:increased secretion:bronchoalveolar lavage (mouse) RGD PMID:18631350 RGD:4145074 NCBI chr 6:12,230,516...12,297,194
Ensembl chr 6:12,290,361...12,297,194 		JBrowse link
G GC GC vitamin D binding protein susceptibility IAGP RGD PMID:12096683 RGD:5129516 NCBI chr 4:71,741,693...71,805,520
Ensembl chr 4:71,741,696...71,804,041 		JBrowse link
G GSTM1 glutathione S-transferase mu 1 severity IAGP DNA:deletion: :
DNA:deletion, haplotype: : (human)		 RGD PMID:9187680 PMID:15125256 RGD:4142513, RGD:12798508 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039 		JBrowse link
G GSTT1 glutathione S-transferase theta 1 susceptibility IAGP DNA:deletion: : RGD PMID:15928955 RGD:4142512
G ICAM1 intercellular adhesion molecule 1 ISO protein:increased expression:bronchial epithelium (rat) RGD PMID:19507274 RGD:2308951 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615 		JBrowse link
G IL10 interleukin 10 ISO protein:decreased expression:lung RGD PMID:19507274 RGD:2308951 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL13 interleukin 13 IEP protein:increased expression:Respiratory Mucosa RGD PMID:14582911 RGD:4759835 NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110 		JBrowse link
G IL15 interleukin 15 IEP mRNA, protein:increased expression:lung RGD PMID:11742275 RGD:4990461 NCBI chr 4:141,636,583...141,733,987
Ensembl chr 4:141,636,583...141,733,987 		JBrowse link
G MPO myeloperoxidase ISO protein:increased expression:lung RGD PMID:11798689 RGD:5130990 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935 		JBrowse link
G NOS2 nitric oxide synthase 2 ISO RGD PMID:19938219 RGD:4891494 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NPY neuropeptide Y EXP CTD Direct Evidence: marker/mechanism CTD PMID:9731035 NCBI chr 7:24,284,190...24,291,862
Ensembl chr 7:24,284,188...24,291,862 		JBrowse link
G VEGFA vascular endothelial growth factor A EXP CTD Direct Evidence: marker/mechanism CTD PMID:19263519 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487 		JBrowse link
chronic rhinitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EDN1 endothelin 1 IEP protein:increased expression:inferior turbinate, nasal gland, inflammatory cell (human) RGD PMID:8845175 RGD:8661738 NCBI chr 6:12,230,516...12,297,194
Ensembl chr 6:12,290,361...12,297,194 		JBrowse link
Chronic Rhinosinusitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD8A CD8 subunit alpha ameliorates IEP protein:decreased expression:blood, T cell (human) RGD PMID:24639246 RGD:124715444 NCBI chr 2:86,784,605...86,808,396
Ensembl chr 2:86,784,610...86,808,396 		JBrowse link
G IL17A interleukin 17A IEP protein:increased expression:uncinate process, nasal mucosa (human) RGD PMID:23613503 RGD:8696039 NCBI chr 6:52,186,375...52,190,638
Ensembl chr 6:52,186,375...52,190,638 		JBrowse link
G IL1RN interleukin 1 receptor antagonist susceptibility IAGP DNA:repeats:intron:IVS2+914_1000dup I/II alleles (human) RGD PMID:16549749 RGD:8549791 NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016 		JBrowse link
G MBL2 mannose binding lectin 2 IEP protein:decreased activity:serum: RGD PMID:23144819 RGD:8693716 NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784 		JBrowse link
G PRG2 proteoglycan 2, pro eosinophil major basic protein disease_progression IEP associated with Nasal Polyps; RGD PMID:24450586 RGD:13506943 NCBI chr11:57,386,780...57,390,650
Ensembl chr11:57,386,780...57,390,650 		JBrowse link
common cold term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX5 arachidonate 5-lipoxygenase IEP protein:increased expression:bronchus RGD PMID:11865407 RGD:4890421 NCBI chr10:45,374,216...45,446,117
Ensembl chr10:45,374,176...45,446,119 		JBrowse link
G ALOX5AP arachidonate 5-lipoxygenase activating protein IEP protein:increased expression:bronchus RGD PMID:11865407 RGD:4890421 NCBI chr13:30,713,485...30,764,426
Ensembl chr13:30,713,478...30,764,426 		JBrowse link
G CX3CL1 C-X3-C motif chemokine ligand 1 IDA RGD PMID:20696083 RGD:4140458 NCBI chr16:57,372,490...57,385,044
Ensembl chr16:57,372,477...57,385,044 		JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 IEP associated with Pulmonary Disease, Chronic Obstructive;protein:increased expression:respiratory epithelial cell RGD PMID:20395558 RGD:4145446 NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308 		JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 IEP protein:increased expression:respiratory system fluid/secretion RGD PMID:15764644 RGD:5135489 NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497 		JBrowse link
G CXCL5 C-X-C motif chemokine ligand 5 IEP associated with Asthma RGD PMID:12751040 RGD:5135264 NCBI chr 4:73,995,642...73,998,677
Ensembl chr 4:73,995,642...73,998,677 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 treatment IEP RGD PMID:28343401 RGD:150521550 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CXCR2 C-X-C motif chemokine receptor 2 ISO RGD PMID:19864593 RGD:5131210 NCBI chr 2:218,125,294...218,137,251
Ensembl chr 2:218,125,289...218,137,251 		JBrowse link
G DEFB4A defensin beta 4A IEP mRNA, protein:increased expression:nasal cavity epithelium, nasal mucus RGD PMID:15034083 RGD:4892264 NCBI chr 8:7,894,677...7,896,716
Ensembl chr 8:7,894,677...7,896,716
Ensembl chr 8:7,894,677...7,896,716 		JBrowse link
G IFNA2 interferon alpha 2 treatment IDA RGD PMID:6381610 RGD:40886344 NCBI chr 9:21,384,255...21,385,398
Ensembl chr 9:21,384,255...21,385,398 		JBrowse link
G IL10 interleukin 10 IDA RGD PMID:20696083 RGD:4140458 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL1A interleukin 1 alpha IEP protein:increased expression:nasal mucus RGD PMID:10358201 RGD:4143183 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493 		JBrowse link
G IL1B interleukin 1 beta IEP protein:increased expression:nasal mucus RGD PMID:7734976 RGD:7401200 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL1RN interleukin 1 receptor antagonist IEP
IDA		 protein:increased expression:nasal mucus RGD PMID:10358201 PMID:18279051 RGD:4143183, RGD:4143207 NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016 		JBrowse link
G IL33 interleukin 33 IEP protein:increased expression:nasal mucus RGD PMID:28471975 RGD:38596342 NCBI chr 9:6,215,149...6,257,983
Ensembl chr 9:6,215,786...6,257,983 		JBrowse link
G IL4 interleukin 4 ISO associated with Asthma;mRNA, protein:increased expression:alveolar macrophage, respiratory system fluid/secretion RGD PMID:20644177 RGD:4140459 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G PRDX5 peroxiredoxin 5 IEP associated with asthma;protein:increased expression:sputum (human) RGD PMID:18219526 RGD:41404684 NCBI chr11:64,318,121...64,321,811
Ensembl chr11:64,318,121...64,321,811 		JBrowse link
G TSLP thymic stromal lymphopoietin IEP protein:increased expression:nasal mucus (human) RGD PMID:28471975 RGD:38596342 NCBI chr 5:111,070,062...111,078,026
Ensembl chr 5:111,070,062...111,078,026 		JBrowse link
cryptogenic organizing pneumonia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TNFRSF1A TNF receptor superfamily member 1A IEP protein:increased expression:lung, macrophage (human) RGD PMID:21144722 RGD:5131112 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114 		JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B IEP protein:increased expression:lung, lymphocyte (human) RGD PMID:21144722 RGD:5131112 NCBI chr 1:12,166,991...12,209,220
Ensembl chr 1:12,166,991...12,209,228 		JBrowse link
desquamative interstitial pneumonia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SFTPC surfactant protein C ISS OMIM:263000 MouseDO NCBI chr 8:22,157,383...22,164,479
Ensembl chr 8:22,156,913...22,164,479 		JBrowse link
Diffuse Panbronchiolitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HLA-B major histocompatibility complex, class I, B susceptibility IAGP DNA:polymorphism:cds:HLA-B*5401 (human) RGD PMID:9731015 RGD:1331522 NCBI chr 6:31,353,875...31,357,179
Ensembl chr 6:31,353,872...31,367,067 		JBrowse link
G MBL2 mannose binding lectin 2 susceptibility IAGP DNA:SNP:exon:p.G54D(rs1800450)(human) RGD PMID:15249448 RGD:8693755 NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784 		JBrowse link
G MUC5AC mucin 5AC, oligomeric mucus/gel-forming IEP protein:decreased expression:bronchiole epithelium RGD PMID:15364771 RGD:7364741 NCBI chr11:1,157,953...1,201,138
Ensembl chr11:1,157,953...1,201,138 		JBrowse link
G MUC5B mucin 5B, oligomeric mucus/gel-forming IAGP DNA:insertion/deletion RGD PMID:15709052 RGD:7349353 NCBI chr11:1,223,066...1,262,172
Ensembl chr11:1,223,066...1,262,172 		JBrowse link
G MUCL3 mucin like 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22152429 NCBI chr 6:30,940,973...30,954,221
Ensembl chr 6:30,934,523...30,954,221 		JBrowse link
G TAP2 transporter 2, ATP binding cassette subfamily B member susceptibility IAGP DNA:polymorphisms:exon: RGD PMID:10323341 RGD:5147847 NCBI chr 6:32,821,831...32,838,739
Ensembl chr 6:32,821,833...32,838,739 		JBrowse link
ethmoid sinusitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL7 C-C motif chemokine ligand 7 IEP protein:increased expression:ethmoid sinus RGD PMID:9800627 RGD:6483785 NCBI chr17:34,270,221...34,272,242
Ensembl chr17:34,270,221...34,272,242 		JBrowse link
Fungal Lung Diseases term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C5 complement C5 ISO RGD PMID:2612053 RGD:5130160 NCBI chr 9:120,952,335...121,074,865
Ensembl chr 9:120,932,987...121,075,195 		JBrowse link
G CCL7 C-C motif chemokine ligand 7 ISO RGD PMID:20045013 RGD:5129686 NCBI chr17:34,270,221...34,272,242
Ensembl chr17:34,270,221...34,272,242 		JBrowse link
G GATA2 GATA binding protein 2 ISO associated with Pneumocystis Infections RGD PMID:16774119 RGD:9587813 NCBI chr 3:128,479,422...128,493,201
Ensembl chr 3:128,479,427...128,493,201 		JBrowse link
G IL13 interleukin 13 ISO protein:increased expression:lung RGD PMID:19752036 PMID:16544260 RGD:4145474, RGD:4145506 NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110 		JBrowse link
G IL33 interleukin 33 ISO protein:increased expression:lung RGD PMID:25746970 RGD:39938968 NCBI chr 9:6,215,149...6,257,983
Ensembl chr 9:6,215,786...6,257,983 		JBrowse link
G NOS2 nitric oxide synthase 2 ISO protein:decreased expression:lung RGD PMID:10639453 RGD:4891455 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G SFTPA1 surfactant protein A1 susceptibility ISO RGD PMID:20413160 RGD:4143489 NCBI chr10:79,610,939...79,615,455
Ensembl chr10:79,610,939...79,615,455 		JBrowse link
G SFTPD surfactant protein D susceptibility ISO
IDA		 RGD PMID:20413160 PMID:20413160 RGD:4143489, RGD:4143489 NCBI chr10:79,937,740...79,982,383
Ensembl chr10:79,937,467...79,982,614 		JBrowse link
G TNF tumor necrosis factor ISO protein:increased expression:lung RGD PMID:16544260 RGD:4145506 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
Human Influenza term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABO ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase susceptibility IAGP DNA:polymorphism:cds:allele AB (human) RGD PMID:6189297 PMID:4375858 RGD:5128836, RGD:39938844 NCBI chr 9:133,250,401...133,275,201
Ensembl chr 9:133,233,278...133,276,024 		JBrowse link
G APOL6 apolipoprotein L6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23326326 NCBI chr22:35,648,446...35,668,404
Ensembl chr22:35,648,446...35,668,404 		JBrowse link
G ATF3 activating transcription factor 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23326326 NCBI chr 1:212,565,407...212,620,777
Ensembl chr 1:212,565,334...212,620,777 		JBrowse link
G C3 complement C3 ISO RGD PMID:21408070 RGD:5129492 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562 		JBrowse link
G CASP1 caspase 1 ISO RGD PMID:19362023 RGD:5130181 NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250 		JBrowse link
G CAT catalase ISO
IDA		 RGD PMID:16804020 PMID:20653246 PMID:19959187 RGD:5130864, RGD:5130201, RGD:5130744 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CCL11 C-C motif chemokine ligand 11 ISO associated with Asthma;protein:increased expression:respiratory system fluid/secretion RGD PMID:12707338 PMID:20656925 RGD:4145439, RGD:4145452 NCBI chr17:34,285,742...34,288,334
Ensembl chr17:34,285,742...34,288,334 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 ISO
EXP		 mRNA:increased expression:lung
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:23326326 PMID:20967263 RGD:4891425 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CCL28 C-C motif chemokine ligand 28 resistance ISO RGD PMID:19847203 RGD:4892196 NCBI chr 5:43,356,975...43,412,391
Ensembl chr 5:43,376,645...43,412,391 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 susceptibility ISO protein:increased expression:lung (mouse) RGD PMID:20656925 PMID:16208318 RGD:4145452, RGD:4892131 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793 		JBrowse link
G CCL8 C-C motif chemokine ligand 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23326326 NCBI chr17:34,319,435...34,321,402
Ensembl chr17:34,319,435...34,321,402 		JBrowse link
G CCR5 C-C motif chemokine receptor 5 severity ISO
IAGP		 DNA:frameshift mutation:cds:p.S185_T195del rs333 (human) RGD PMID:19039768 PMID:18617426 PMID:20875295 RGD:4892119, RGD:4892122, RGD:4892063 NCBI chr 3:46,370,142...46,376,206
Ensembl chr 3:46,370,946...46,376,206 		JBrowse link
G CD14 CD14 molecule ISO RGD PMID:17825924 RGD:4144809 NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,700 		JBrowse link
G CD209 CD209 molecule susceptibility IEP RGD PMID:21191006 RGD:5131189 NCBI chr19:7,739,993...7,747,534
Ensembl chr19:7,739,993...7,747,564 		JBrowse link
G CD28 CD28 molecule ISO RGD PMID:21389258 RGD:5131611 NCBI chr 2:203,706,482...203,738,912
Ensembl chr 2:203,706,475...203,738,912 		JBrowse link
G CD40 CD40 molecule ISO RGD PMID:19922665 RGD:5132270 NCBI chr20:46,118,314...46,129,858
Ensembl chr20:46,118,271...46,129,863 		JBrowse link
G CD80 CD80 molecule ISO RGD PMID:19922665 PMID:10604996 RGD:5132270, RGD:5132623 NCBI chr 3:119,524,293...119,559,614
Ensembl chr 3:119,524,293...119,559,614 		JBrowse link
G CD86 CD86 molecule ISO protein:increased expression:mediastinal lymph node, B cell (mouse) RGD PMID:19933871 RGD:4892570 NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139 		JBrowse link
G CRP C-reactive protein IEP protein:increased expression:serum RGD PMID:21509252 RGD:5131277 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589 		JBrowse link
G CSF2 colony stimulating factor 2 ISO
IDA		 RGD PMID:21474645 PMID:20427198 RGD:5131470, RGD:5131472 NCBI chr 5:132,073,789...132,076,170
Ensembl chr 5:132,073,789...132,076,170 		JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 ISO protein:increased expression:respiratory system fluid/secretion
protein:increased expression:lung, serum		 RGD PMID:20656925 PMID:17348295 RGD:4145452, RGD:4145366 NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308 		JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23326326 NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497 		JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 ISO mRNA:increased expression:lung RGD PMID:21251691 PMID:20967263 RGD:5135026, RGD:4891425 NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196 		JBrowse link
G DDX60 DExD/H-box helicase 60 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23326326 NCBI chr 4:168,216,294...168,325,979
Ensembl chr 4:168,216,291...168,318,883 		JBrowse link
G EGR1 early growth response 1 ISO mRNA:increased expression:frontal cortex (mouse) RGD PMID:21289196 RGD:5131660 NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303 		JBrowse link
G EIF2AK2 eukaryotic translation initiation factor 2 alpha kinase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23326326 NCBI chr 2:37,099,210...37,156,980
Ensembl chr 2:37,099,210...37,157,522 		JBrowse link
G FOXP2 forkhead box P2 ISO RGD PMID:18248790 RGD:11536002 NCBI chr 7:114,086,327...114,693,765
Ensembl chr 7:114,086,327...114,693,772 		JBrowse link
G GBP1 guanylate binding protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23326326 NCBI chr 1:89,052,319...89,065,208
Ensembl chr 1:89,051,882...89,065,360 		JBrowse link
G HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23326326 NCBI chr 4:88,457,119...88,506,163
Ensembl chr 4:88,457,119...88,506,163 		JBrowse link
G HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23326326 NCBI chr 4:88,378,852...88,443,097
Ensembl chr 4:88,378,739...88,443,097 		JBrowse link
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 IMP RGD PMID:19386707 RGD:4144816 NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,577,902...32,589,848 		JBrowse link
G HLA-G major histocompatibility complex, class I, G IEP RGD PMID:21087648 RGD:5144131 NCBI chr 6:29,826,474...29,831,021
Ensembl chr 6:29,826,967...29,831,125 		JBrowse link
G IFI27 interferon alpha inducible protein 27 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23326326 NCBI chr14:94,105,894...94,116,690
Ensembl chr14:94,104,836...94,116,695 		JBrowse link
G IFI35 interferon induced protein 35 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23326326 NCBI chr17:43,006,784...43,014,456
Ensembl chr17:43,006,740...43,014,456 		JBrowse link
G IFI44 interferon induced protein 44 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23326326 NCBI chr 1:78,649,789...78,664,078
Ensembl chr 1:78,649,796...78,664,078 		JBrowse link
G IFI44L interferon induced protein 44 like EXP CTD Direct Evidence: marker/mechanism CTD PMID:23326326 NCBI chr 1:78,620,448...78,646,145
Ensembl chr 1:78,619,902...78,646,145 		JBrowse link
G IFI6 interferon alpha inducible protein 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23326326 NCBI chr 1:27,666,064...27,672,192
Ensembl chr 1:27,666,064...27,672,212 		JBrowse link
G IFIH1 interferon induced with helicase C domain 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23326326 NCBI chr 2:162,267,074...162,318,684
Ensembl chr 2:162,267,074...162,318,684 		JBrowse link
G IFIT1 interferon induced protein with tetratricopeptide repeats 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23326326 NCBI chr10:89,392,623...89,406,487
Ensembl chr10:89,392,546...89,406,487 		JBrowse link
G IFIT2 interferon induced protein with tetratricopeptide repeats 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23326326 NCBI chr10:89,302,046...89,309,271
Ensembl chr10:89,283,694...89,309,271 		JBrowse link
G IFIT3 interferon induced protein with tetratricopeptide repeats 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23326326 NCBI chr10:89,327,997...89,340,968
Ensembl chr10:89,327,307...89,377,473 		JBrowse link
G IFIT5 interferon induced protein with tetratricopeptide repeats 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23326326 NCBI chr10:89,414,568...89,420,997
Ensembl chr10:89,414,568...89,421,605 		JBrowse link
G IFITM3 interferon induced transmembrane protein 3 susceptibility EXP
IAGP		 CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Influenza, severe, susceptibility to		 CTD
ClinVar
OMIM		 PMID:20943977 PMID:22446628 PMID:23326326 NCBI chr11:319,676...320,860
Ensembl chr11:319,676...329,475 		JBrowse link
G IL10 interleukin 10 susceptibility ISO RGD PMID:20200252 RGD:4140426 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL12B interleukin 12B ISO RGD PMID:16389596 RGD:4145426 NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,863 		JBrowse link
G IL13 interleukin 13 IEP protein:increased expression:serum RGD PMID:20003352 RGD:4888530 NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110 		JBrowse link
G IL15 interleukin 15 IMP
ISO		 mRNA, protein:increased expression:lung RGD PMID:19234203 PMID:21098221 PMID:20212069 RGD:4996472, RGD:4994196, RGD:4996471 NCBI chr 4:141,636,583...141,733,987
Ensembl chr 4:141,636,583...141,733,987 		JBrowse link
G IL15RA interleukin 15 receptor subunit alpha ISO RGD PMID:21098221 RGD:4994196 NCBI chr10:5,948,900...5,978,741
Ensembl chr10:5,943,639...5,978,187 		JBrowse link
G IL17A interleukin 17A ISO mRNA, protein:increased expression:lung RGD PMID:19783685 PMID:19265125 RGD:4889102, RGD:4889150 NCBI chr 6:52,186,375...52,190,638
Ensembl chr 6:52,186,375...52,190,638 		JBrowse link
G IL17RA interleukin 17 receptor A ISO RGD PMID:19783685 RGD:4889102 NCBI chr22:17,085,000...17,115,693
Ensembl chr22:17,084,954...17,115,693 		JBrowse link
G IL18 interleukin 18 ISO RGD PMID:15606801 RGD:4889964 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096 		JBrowse link
G IL1A interleukin 1 alpha ISO protein:increased expression:lung RGD PMID:11535264 RGD:4142860 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493 		JBrowse link
G IL1B interleukin 1 beta ISO RGD PMID:20438620 RGD:4142822 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL1RN interleukin 1 receptor antagonist disease_progression IEP
IDA		 protein:increased expression:serum RGD PMID:20840779 PMID:9439800 RGD:4143203, RGD:4143228 NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016 		JBrowse link
G IL2 interleukin 2 IEP protein:increased expression:serum RGD PMID:21603856 RGD:5147905 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725 		JBrowse link
G IL22 interleukin 22 ISO RGD PMID:21178015 PMID:20504940 RGD:5147404, RGD:5147405 NCBI chr12:68,248,242...68,253,604
Ensembl chr12:68,248,242...68,253,604 		JBrowse link
G IL4 interleukin 4 ISO RGD PMID:21092162 RGD:5128546 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G IL6 interleukin 6 ISO RGD PMID:20731583 RGD:4143268 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G IRF7 interferon regulatory factor 7 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23326326 NCBI chr11:612,555...615,950
Ensembl chr11:612,553...615,983 		JBrowse link
G ISG15 ISG15 ubiquitin like modifier EXP CTD Direct Evidence: marker/mechanism CTD PMID:23326326 NCBI chr 1:1,013,497...1,014,540
Ensembl chr 1:1,001,138...1,014,540 		JBrowse link
G LAMP3 lysosomal associated membrane protein 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23326326 NCBI chr 3:183,122,215...183,163,813
Ensembl chr 3:183,122,215...183,163,839 		JBrowse link
G LY6E lymphocyte antigen 6 family member E EXP CTD Direct Evidence: marker/mechanism CTD PMID:23326326 NCBI chr 8:143,018,529...143,022,409
Ensembl chr 8:143,017,982...143,023,832 		JBrowse link
G LYST lysosomal trafficking regulator EXP CTD Direct Evidence: marker/mechanism CTD PMID:26597256 NCBI chr 1:235,661,031...235,883,713
Ensembl chr 1:235,661,041...235,883,724 		JBrowse link
G MMP9 matrix metallopeptidase 9 ISO protein:increased activity:lung, heart, brain RGD PMID:20299740 RGD:5130855 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MX1 MX dynamin like GTPase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23326326 NCBI chr21:41,420,558...41,459,214
Ensembl chr21:41,420,020...41,470,071 		JBrowse link
G MX2 MX dynamin like GTPase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23326326 NCBI chr21:41,362,027...41,409,393
Ensembl chr21:41,361,999...41,409,393 		JBrowse link
G NOS1 nitric oxide synthase 1 ISO protein:increased expression:hippocampus RGD PMID:9552178 RGD:5132870 NCBI chr12:117,208,142...117,361,626
Ensembl chr12:117,208,142...117,452,170 		JBrowse link
G NOS2 nitric oxide synthase 2 ISO mRNA:increased expression:olfactory epithelium
mRNA,protein:increased expression:brain		 RGD PMID:17674769 PMID:18080188 PMID:17030871 RGD:4891919, RGD:4891937, RGD:4891952 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G OAS1 2'-5'-oligoadenylate synthetase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23326326 NCBI chr12:112,906,962...112,933,219
Ensembl chr12:112,905,856...112,933,219 		JBrowse link
G OAS2 2'-5'-oligoadenylate synthetase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23326326 NCBI chr12:112,978,519...113,011,723
Ensembl chr12:112,978,395...113,011,723 		JBrowse link
G OAS3 2'-5'-oligoadenylate synthetase 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23326326 NCBI chr12:112,938,474...112,973,251
Ensembl chr12:112,938,051...112,976,460 		JBrowse link
G OASL 2'-5'-oligoadenylate synthetase like EXP CTD Direct Evidence: marker/mechanism CTD PMID:23326326 NCBI chr12:121,017,761...121,039,246
Ensembl chr12:121,017,763...121,039,246 		JBrowse link
G PARP12 poly(ADP-ribose) polymerase family member 12 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23326326 NCBI chr 7:140,023,749...140,062,951
Ensembl chr 7:140,023,749...140,062,951 		JBrowse link
G PLSCR1 phospholipid scramblase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23326326 NCBI chr 3:146,515,180...146,544,607
Ensembl chr 3:146,515,180...146,544,856 		JBrowse link
G PRF1 perforin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26597256 NCBI chr10:70,597,348...70,602,741
Ensembl chr10:70,597,348...70,602,759 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO RGD PMID:16272346 RGD:5143925 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G RIGI RNA sensor RIG-I EXP CTD Direct Evidence: marker/mechanism CTD PMID:23326326 NCBI chr 9:32,455,302...32,526,196
Ensembl chr 9:32,455,302...32,526,208 		JBrowse link
G RSAD2 radical S-adenosyl methionine domain containing 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23326326 NCBI chr 2:6,865,885...6,898,239
Ensembl chr 2:6,865,557...6,898,239 		JBrowse link
G RTP4 receptor transporter protein 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23326326 NCBI chr 3:187,368,385...187,372,076
Ensembl chr 3:187,368,385...187,372,076 		JBrowse link
G SAMD9 sterile alpha motif domain containing 9 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23326326 NCBI chr 7:93,099,518...93,117,979
Ensembl chr 7:93,099,513...93,118,023 		JBrowse link
G SCO2 synthesis of cytochrome C oxidase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23326326 NCBI chr22:50,523,568...50,526,442
Ensembl chr22:50,523,568...50,526,461 		JBrowse link
G SERPING1 serpin family G member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23326326 NCBI chr11:57,597,685...57,614,848
Ensembl chr11:57,597,387...57,619,171 		JBrowse link
G SFTPD surfactant protein D ISO RGD PMID:16787926 RGD:4143518 NCBI chr10:79,937,740...79,982,383
Ensembl chr10:79,937,467...79,982,614 		JBrowse link
G SIGLEC1 sialic acid binding Ig like lectin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23326326 NCBI chr20:3,686,970...3,712,600
Ensembl chr20:3,686,970...3,712,600 		JBrowse link
G SLC22A8 solute carrier family 22 member 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23129053 NCBI chr11:62,992,824...63,015,841
Ensembl chr11:62,989,154...63,015,841 		JBrowse link
G STAT1 signal transducer and activator of transcription 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23326326 NCBI chr 2:190,969,149...191,014,171
Ensembl chr 2:190,908,460...191,020,960 		JBrowse link
G TDRD7 tudor domain containing 7 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23326326 NCBI chr 9:97,412,096...97,496,125
Ensembl chr 9:97,412,096...97,496,125 		JBrowse link
G TLR2 toll like receptor 2 IEP protein:increased expression:monocyte RGD PMID:18657324 RGD:4145339 NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,070...153,706,260 		JBrowse link
G TLR3 toll like receptor 3 ISO mRNA:increased expression:lung (mouse) RGD PMID:16789835 PMID:18654661 RGD:5129219, RGD:5129136 NCBI chr 4:186,069,156...186,088,073
Ensembl chr 4:186,068,911...186,088,073 		JBrowse link
G TMPRSS11D transmembrane serine protease 11D EXP CTD Direct Evidence: marker/mechanism CTD PMID:20237084 PMID:23072892 NCBI chr 4:67,820,876...67,884,002
Ensembl chr 4:67,820,876...67,884,002 		JBrowse link
G TMPRSS2 transmembrane serine protease 2 EXP CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:20237084 PMID:21123387 PMID:23072892 PMID:26889029 PMID:28778717 More... NCBI chr21:41,464,305...41,508,158
Ensembl chr21:41,464,300...41,531,116 		JBrowse link
G TMPRSS4 transmembrane serine protease 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26889029 NCBI chr11:118,077,078...118,125,505
Ensembl chr11:118,077,012...118,121,890 		JBrowse link
G TNF tumor necrosis factor IEP protein:increased expression:serum RGD PMID:21062445 RGD:5128683 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFAIP6 TNF alpha induced protein 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23326326 NCBI chr 2:151,357,592...151,381,340
Ensembl chr 2:151,357,592...151,380,046 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A ISO
IEP		 protein:increased expression:serum (human) RGD PMID:17182684 PMID:19497758 RGD:5131157, RGD:5131432 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114 		JBrowse link
G TNFSF10 TNF superfamily member 10 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23326326 NCBI chr 3:172,505,508...172,523,430
Ensembl chr 3:172,505,508...172,523,475 		JBrowse link
G TOR1B torsin family 1 member B EXP CTD Direct Evidence: marker/mechanism CTD PMID:23326326 NCBI chr 9:129,803,184...129,811,281
Ensembl chr 9:129,803,157...129,811,281 		JBrowse link
G TREX1 three prime repair exonuclease 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23326326 NCBI chr 3:48,465,830...48,467,645
Ensembl chr 3:48,465,811...48,467,645 		JBrowse link
G TRIM22 tripartite motif containing 22 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23326326 NCBI chr11:5,689,790...5,710,863
Ensembl chr11:5,689,610...5,737,089 		JBrowse link
G UBE2L6 ubiquitin conjugating enzyme E2 L6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23326326 NCBI chr11:57,551,662...57,567,935
Ensembl chr11:57,551,656...57,568,284 		JBrowse link
G UGCG UDP-glucose ceramide glucosyltransferase EXP CTD Direct Evidence: marker/mechanism CTD PMID:33639165 NCBI chr 9:111,896,814...111,935,369
Ensembl chr 9:111,896,814...111,935,369 		JBrowse link
G XAF1 XIAP associated factor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23326326 NCBI chr17:6,755,447...6,775,647
Ensembl chr17:6,755,447...6,775,647 		JBrowse link
G XIST X inactive specific transcript EXP CTD Direct Evidence: marker/mechanism CTD PMID:23326326 NCBI chr  X:73,820,651...73,852,753
Ensembl chr  X:73,820,649...73,852,723 		JBrowse link
G ZCCHC2 zinc finger CCHC-type containing 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23326326 NCBI chr18:62,523,025...62,586,729
Ensembl chr18:62,523,025...62,587,709 		JBrowse link
idiopathic interstitial pneumonia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CXCL5 C-X-C motif chemokine ligand 5 IEP associated with Scleroderma, Diffuse
protein:increased expression:serum		 RGD PMID:18432520 PMID:16085216 RGD:5135258, RGD:5135260 NCBI chr 4:73,995,642...73,998,677
Ensembl chr 4:73,995,642...73,998,677 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 IEP protein:increased expression:lung, alveolar macrophage (human) RGD PMID:19218648 RGD:4145518 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615 		JBrowse link
G IL6 interleukin 6 ISO protein:increased expression:bronchoalveolar lavage (rat) RGD PMID:10988147 RGD:11062092 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G KEAP1 kelch like ECH associated protein 1 IEP protein:increased expression:hyperplastic lung epithelium, alveolus (human) RGD PMID:20718723 RGD:6893300 NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558 		JBrowse link
G MTOR mechanistic target of rapamycin kinase IMP RGD PMID:21444868 RGD:7245946 NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556 		JBrowse link
G SCGB1A1 secretoglobin family 1A member 1 IEP protein:increased expression:serum RGD PMID:15467329 RGD:5144148 NCBI chr11:62,419,033...62,423,195
Ensembl chr11:62,405,103...62,423,195 		JBrowse link
idiopathic pulmonary fibrosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA3 ATP binding cassette subfamily A member 3 IAGP ClinVar Annotator: match by term: Interstitial lung disease 2 ClinVar PMID:15976379 PMID:17597647 PMID:18024538 PMID:18246475 PMID:18317237 More... NCBI chr16:2,275,881...2,340,728
Ensembl chr16:2,275,881...2,340,746 		JBrowse link
G AHRR aryl hydrocarbon receptor repressor IAGP ClinVar Annotator: match by term: Interstitial lung disease 2 ClinVar PMID:12629597 PMID:28492532 NCBI chr 5:321,714...438,285
Ensembl chr 5:321,714...438,291 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 IEP mRNA:increased expression:blood plasma (human) RGD PMID:31874165 RGD:152995482 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751 		JBrowse link
G APOA1 apolipoprotein A1 IEP protein: decreased expression: respiratory system fluid/secretion RGD PMID:20463180 RGD:5508222 NCBI chr11:116,835,751...116,837,950
Ensembl chr11:116,835,751...116,837,622 		JBrowse link
G ATP11A ATPase phospholipid transporting 11A EXP CTD Direct Evidence: marker/mechanism CTD PMID:23583980 NCBI chr13:112,690,038...112,887,168
Ensembl chr13:112,690,038...112,887,168 		JBrowse link
G BMP1 bone morphogenetic protein 1 IAGP ClinVar Annotator: match by term: Fibrocystic pulmonary dysplasia
ClinVar Annotator: match by term: Fibrocystic pulmonary dysplasia | ClinVar Annotator: match by term: Interstitial lung disease 2		 ClinVar PMID:24033266 PMID:25741868 PMID:28492532 NCBI chr 8:22,165,372...22,212,326
Ensembl chr 8:22,165,140...22,212,326 		JBrowse link
G BRD4 bromodomain containing 4 IDA RGD PMID:23759512 RGD:9586353 NCBI chr19:15,235,519...15,332,539
Ensembl chr19:15,235,519...15,332,545 		JBrowse link
G BRD9 bromodomain containing 9 IAGP ClinVar Annotator: match by term: Interstitial lung disease 2 ClinVar PMID:12629597 PMID:28492532 NCBI chr 5:863,741...892,801
Ensembl chr 5:850,291...892,801 		JBrowse link
G CCL13 C-C motif chemokine ligand 13 ISO CTD Direct Evidence: therapeutic CTD PMID:28434932 NCBI chr17:34,356,480...34,358,610
Ensembl chr17:34,356,480...34,358,610 		JBrowse link
G CEP72 centrosomal protein 72 IAGP ClinVar Annotator: match by term: Interstitial lung disease 2 ClinVar PMID:12629597 PMID:28492532 NCBI chr 5:612,340...676,616
Ensembl chr 5:612,340...667,168 		JBrowse link
G CFLAR CASP8 and FADD like apoptosis regulator IEP mRNA,protein:increased expression:lung myofibroblast: RGD PMID:22582174 RGD:11341695 NCBI chr 2:201,116,164...201,176,687
Ensembl chr 2:201,116,154...201,176,687 		JBrowse link
G CTC1 CST telomere replication complex component 1 IAGP ClinVar Annotator: match by term: Interstitial lung disease 2 ClinVar NCBI chr17:8,224,815...8,248,056
Ensembl chr17:8,224,815...8,248,058 		JBrowse link
G CXCL5 C-X-C motif chemokine ligand 5 IAGP
IEP		 DNA:polymorphism:promoter:-156G>C (human)
protein:increased expression:lung, macrophage, type II pneumocyte		 RGD PMID:20137269 PMID:11751193 RGD:5135241, RGD:5135250 NCBI chr 4:73,995,642...73,998,677
Ensembl chr 4:73,995,642...73,998,677 		JBrowse link
G DDR1 discoidin domain receptor tyrosine kinase 1 treatment IEP
ISO		 mRNA:increased expression:lung (human) RGD PMID:30119248 PMID:30119248 RGD:151347411, RGD:151347411 NCBI chr 6:30,880,970...30,900,156
Ensembl chr 6:30,876,421...30,900,156 		JBrowse link
G DPP9 dipeptidyl peptidase 9 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23583980 NCBI chr19:4,675,227...4,723,842
Ensembl chr19:4,674,341...4,724,673 		JBrowse link
G DSP desmoplakin EXP
IAGP		 CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Interstitial lung disease 2		 CTD
ClinVar		 PMID:23583980 NCBI chr 6:7,541,671...7,586,714
Ensembl chr 6:7,541,338...7,586,714 		JBrowse link
G DTNBP1 dystrobrevin binding protein 1 IAGP ClinVar Annotator: match by term: Interstitial lung disease 2 ClinVar NCBI chr 6:15,522,807...15,663,058
Ensembl chr 6:15,522,807...15,663,058 		JBrowse link
G EHMT2 euchromatic histone lysine methyltransferase 2 IDA RGD PMID:24652950 RGD:9589169 NCBI chr 6:31,879,759...31,897,698
Ensembl chr 6:31,879,759...31,897,698 		JBrowse link
G EP300 E1A binding protein p300 treatment IEP
ISO		 mRNA:increased expression:lung (human) RGD PMID:30119248 PMID:30119248 RGD:151347411, RGD:151347411 NCBI chr22:41,092,592...41,180,077
Ensembl chr22:41,092,592...41,180,077 		JBrowse link
G ESR1 estrogen receptor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30165855 NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619 		JBrowse link
G EXOC3 exocyst complex component 3 IAGP ClinVar Annotator: match by term: Interstitial lung disease 2 ClinVar PMID:12629597 PMID:28492532 NCBI chr 5:443,176...467,290
Ensembl chr 5:443,175...471,937 		JBrowse link
G EXOC3-AS1 EXOC3 antisense RNA 1 IAGP ClinVar Annotator: match by term: Interstitial lung disease 2 ClinVar PMID:12629597 PMID:28492532 NCBI chr 5:441,835...443,160
Ensembl chr 5:441,498...443,160 		JBrowse link
G F3 coagulation factor III, tissue factor IEP protein:increased expression:respiratory system fluid/secretion RGD PMID:10946084 RGD:11060143 NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759 		JBrowse link
G FAM13A family with sequence similarity 13 member A EXP
IAGP		 CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Interstitial lung disease 2		 CTD
ClinVar		 PMID:23583980 NCBI chr 4:88,725,960...89,057,185
Ensembl chr 4:88,725,955...89,111,398 		JBrowse link
G FAS Fas cell surface death receptor ISO RGD PMID:15148335 RGD:11049166 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605 		JBrowse link
G FASLG Fas ligand ISO RGD PMID:15148335 RGD:11049166 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876 		JBrowse link
G FGFR2 fibroblast growth factor receptor 2 IEP protein:increased expression:lung (human) RGD PMID:29722558 RGD:155791445 NCBI chr10:121,478,330...121,598,458
Ensembl chr10:121,478,332...121,598,458 		JBrowse link
G GPER1 G protein-coupled estrogen receptor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30165855 NCBI chr 7:1,087,118...1,093,810
Ensembl chr 7:1,082,208...1,093,815 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha EXP CTD Direct Evidence: therapeutic CTD PMID:28434932 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259 		JBrowse link
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 susceptibility IAGP DNA:polymorphism (human) RGD PMID:21373184 RGD:5147566 NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,577,902...32,589,848 		JBrowse link
G HPS4 HPS4 biogenesis of lysosomal organelles complex 3 subunit 2 IAGP ClinVar Annotator: match by term: Interstitial lung disease 2 ClinVar NCBI chr22:26,443,109...26,483,863
Ensembl chr22:26,443,107...26,483,931 		JBrowse link
G IL1RL1 interleukin 1 receptor like 1 IEP protein:increased expression:serum RGD PMID:14555548 RGD:5144236 NCBI chr 2:102,311,563...102,352,356
Ensembl chr 2:102,311,502...102,352,037 		JBrowse link
G IL1RN interleukin 1 receptor antagonist IAGP ClinVar Annotator: match by term: Interstitial lung disease 2 ClinVar PMID:16199547 PMID:19494218 PMID:21792839 PMID:22940634 PMID:26100510 More... NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016 		JBrowse link
G IL2RA interleukin 2 receptor subunit alpha IEP RGD PMID:21309737 RGD:5147438 NCBI chr10:6,010,689...6,062,367
Ensembl chr10:6,010,689...6,062,370 		JBrowse link
G LAMA3 laminin subunit alpha 3 IAGP ClinVar Annotator: match by term: Interstitial lung disease 2 ClinVar NCBI chr18:23,689,453...23,955,066
Ensembl chr18:23,689,453...23,956,222 		JBrowse link
G LOC110806263 TERT 5' regulatory region IAGP ClinVar Annotator: match by term: Idiopathic Pulmonary Fibrosis
ClinVar Annotator: match by term: Idiopathic Pulmonary Fibrosis | ClinVar Annotator: match by term: Idiopathic fibrosing alveolitis, chronic form | ClinVar Annotator: match by term: Interstitial lung disease 2		 ClinVar PMID:16199547 PMID:16247010 PMID:17392301 PMID:17460043 PMID:19489057 More... NCBI chr 5:1,294,628...1,298,988 JBrowse link
G LOC110806264 TERT enhancer in intron 2 IAGP ClinVar Annotator: match by term: Interstitial lung disease 2 ClinVar PMID:28492532 NCBI chr 5:1,286,474...1,287,720 JBrowse link
G LOC110806306 telomerase RNA component (TERC) promoter IAGP ClinVar Annotator: match by term: Interstitial lung disease 2 ClinVar PMID:17392301 NCBI chr 3:169,764,689...169,765,858 JBrowse link
G LOC123493259 Sharpr-MPRA regulatory region 13256 IAGP ClinVar Annotator: match by term: Interstitial lung disease 2 ClinVar PMID:28492532 NCBI chr 5:1,276,694...1,276,988 JBrowse link
G LOC129999976 ATAC-STARR-seq lymphoblastoid silent region 18982 IAGP ClinVar Annotator: match by term: Fibrocystic pulmonary dysplasia | ClinVar Annotator: match by term: Interstitial lung disease 2 ClinVar
G MIR184 microRNA 184 IEP RNA:decreased expression:blood plasma (human) RGD PMID:31874165 RGD:152995482 NCBI chr15:79,209,788...79,209,871
Ensembl chr15:79,209,788...79,209,871 		JBrowse link
G MIR31 microRNA 31 IEP RNA:increased expression:blood plasma (human) RGD PMID:31874165 RGD:152995482 NCBI chr 9:21,512,115...21,512,185
Ensembl chr 9:21,512,115...21,512,185 		JBrowse link
G MMP1 matrix metallopeptidase 1 IEP
IAGP		 protein:increased expression:lung,bronchoalveolar lavage fluid:
ClinVar Annotator: match by term: Interstitial lung disease 2		 ClinVar
RGD		 PMID:18447576 RGD:4890373 NCBI chr11:102,789,919...102,798,160
Ensembl chr11:102,789,401...102,798,160 		JBrowse link
G MMP19 matrix metallopeptidase 19 IAGP ClinVar Annotator: match by term: Interstitial lung disease 2 ClinVar NCBI chr12:55,835,433...55,842,936
Ensembl chr12:55,835,433...55,842,966 		JBrowse link
G MMP3 matrix metallopeptidase 3 IEP
EXP		 mRNA, protein:increased expression:lung
CTD Direct Evidence: therapeutic		 CTD
RGD		 PMID:28434932 PMID:21871427 RGD:8694097 NCBI chr11:102,835,801...102,843,609
Ensembl chr11:102,835,801...102,843,609 		JBrowse link
G MUC1 mucin 1, cell surface associated IEP protein:increased expression:serum: RGD PMID:22963039 RGD:7244290 NCBI chr 1:155,185,824...155,192,915
Ensembl chr 1:155,185,824...155,192,916 		JBrowse link
G MUC5B mucin 5B, oligomeric mucus/gel-forming susceptibility EXP
IAGP		 CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Interstitial lung disease 2
ClinVar Annotator: match by term: Fibrocystic pulmonary dysplasia		 CTD
ClinVar
OMIM		 PMID:21506741 PMID:21506748 PMID:23321605 PMID:23583980 PMID:23692170 More... NCBI chr11:1,223,066...1,262,172
Ensembl chr11:1,223,066...1,262,172 		JBrowse link
G MUC5B-AS1 MUC5B antisense RNA 1 IAGP ClinVar Annotator: match by term: Interstitial lung disease 2 ClinVar PMID:24033266 PMID:25741868 NCBI chr11:1,242,261...1,249,676
Ensembl chr11:1,242,261...1,249,676 		JBrowse link
G NKD2 NKD inhibitor of WNT signaling pathway 2 IAGP ClinVar Annotator: match by term: Interstitial lung disease 2 ClinVar PMID:12629597 PMID:28492532 NCBI chr 5:1,008,802...1,038,943
Ensembl chr 5:1,008,802...1,038,943 		JBrowse link
G NKX2-1 NK2 homeobox 1 IAGP ClinVar Annotator: match by term: Interstitial lung disease 2 ClinVar PMID:25741868 PMID:28492532 NCBI chr14:36,516,397...36,520,232
Ensembl chr14:36,516,392...36,521,149 		JBrowse link
G NKX2-1-AS1 NKX2-1 antisense RNA 1 IAGP ClinVar Annotator: match by term: Interstitial lung disease 2 ClinVar PMID:25741868 NCBI chr14:36,519,278...36,523,016
Ensembl chr14:36,519,278...36,523,016 		JBrowse link
G NTRK2 neurotrophic receptor tyrosine kinase 2 IEP mRNA:increased expression:lung RGD PMID:21330466 RGD:5684550 NCBI chr 9:84,668,522...85,027,054
Ensembl chr 9:84,668,375...85,095,751 		JBrowse link
G PARN poly(A)-specific ribonuclease EXP CTD Direct Evidence: marker/mechanism CTD PMID:25848748 NCBI chr16:14,435,701...14,630,260
Ensembl chr16:14,435,700...14,632,728 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 IEP mRNA,protein:increased expression, increased activity:fibroblast RGD PMID:23260200 RGD:10413908 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G PDCD6 programmed cell death 6 IAGP ClinVar Annotator: match by term: Interstitial lung disease 2 ClinVar PMID:12629597 PMID:28492532 NCBI chr 5:271,646...314,974
Ensembl chr 5:271,621...314,974 		JBrowse link
G PLAU plasminogen activator, urokinase EXP CTD Direct Evidence: therapeutic CTD PMID:18491991 NCBI chr10:73,909,164...73,917,494
Ensembl chr10:73,909,177...73,917,496 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 IAGP
IEP
IDA		 DNA:SNPs: :3050G>C, 8473C>T (human)
protein:decreased expression:lung:		 RGD PMID:21319594 PMID:14511257 PMID:20203246 RGD:5135280, RGD:5135507, RGD:5135461 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G RTEL1 regulator of telomere elongation helicase 1 EXP
IAGP		 CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Interstitial lung disease 2
ClinVar Annotator: match by term: Fibrocystic pulmonary dysplasia		 CTD
ClinVar		 PMID:16199547 PMID:23329068 PMID:23453664 PMID:23959892 PMID:24009516 More... NCBI chr20:63,657,810...63,696,253
Ensembl chr20:63,657,810...63,696,253 		JBrowse link
G RTEL1-TNFRSF6B RTEL1-TNFRSF6B readthrough (NMD candidate) IAGP ClinVar Annotator: match by term: Interstitial lung disease 2
ClinVar Annotator: match by term: Fibrocystic pulmonary dysplasia		 ClinVar PMID:16199547 PMID:23329068 PMID:23453664 PMID:23959892 PMID:24009516 More... NCBI chr20:63,657,810...63,698,698
Ensembl chr20:63,659,300...63,698,684 		JBrowse link
G RTKN2 rhotekin 2 IAGP ClinVar Annotator: match by term: Interstitial lung disease 2 ClinVar NCBI chr10:62,183,900...62,268,844
Ensembl chr10:62,183,035...62,268,844 		JBrowse link
G SDHA succinate dehydrogenase complex flavoprotein subunit A IAGP ClinVar Annotator: match by term: Interstitial lung disease 2 ClinVar PMID:12629597 PMID:28492532 NCBI chr 5:218,320...268,746
Ensembl chr 5:218,303...257,082 		JBrowse link
G SETD2 SET domain containing 2, histone lysine methyltransferase exacerbates IAGP associated with lung squamous cell carcinoma; DNA:mutations:multiple (human) RGD PMID:33533494 RGD:150429642 NCBI chr 3:47,016,436...47,164,840
Ensembl chr 3:47,016,428...47,164,113 		JBrowse link
G SFTA3 surfactant associated 3 IAGP ClinVar Annotator: match by term: Interstitial lung disease 2 ClinVar PMID:25741868 PMID:28492532 NCBI chr14:36,473,288...36,519,556
Ensembl chr14:36,473,288...36,513,829
Ensembl chr14:36,473,288...36,513,829 		JBrowse link
G SFTPA1 surfactant protein A1 IAGP ClinVar Annotator: match by term: Pulmonary fibrosis, idiopathic, susceptibility to
ClinVar Annotator: match by term: Interstitial lung disease 2		 ClinVar PMID:13680361 PMID:24033266 PMID:25741868 NCBI chr10:79,610,939...79,615,455
Ensembl chr10:79,610,939...79,615,455 		JBrowse link
G SFTPA2 surfactant protein A2 IAGP
EXP		 ClinVar Annotator: match by term: Fibrocystic pulmonary dysplasia | ClinVar Annotator: match by term: Interstitial lung disease 2
CTD Direct Evidence: marker/mechanism		 OMIM
ClinVar
CTD		 PMID:16292672 PMID:17580966 PMID:19100526 PMID:20466729 PMID:22853774 More... NCBI chr10:79,555,852...79,560,407
Ensembl chr10:79,555,852...79,560,407 		JBrowse link
G SFTPC surfactant protein C EXP
IAGP		 CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Fibrocystic pulmonary dysplasia
ClinVar Annotator: match by term: Interstitial lung disease 2
ClinVar Annotator: match by term: Fibrocystic pulmonary dysplasia | ClinVar Annotator: match by term: Interstitial lung disease 2		 CTD
ClinVar		 PMID:14735158 PMID:15039969 PMID:15516475 PMID:15709974 PMID:18383112 More... NCBI chr 8:22,157,383...22,164,479
Ensembl chr 8:22,156,913...22,164,479 		JBrowse link
G SLC12A7 solute carrier family 12 member 7 IAGP ClinVar Annotator: match by term: Interstitial lung disease 2 ClinVar PMID:12629597 PMID:28492532 NCBI chr 5:1,050,384...1,155,899
Ensembl chr 5:1,050,384...1,112,063 		JBrowse link
G SLC6A18 solute carrier family 6 member 18 IAGP ClinVar Annotator: match by term: Interstitial lung disease 2 ClinVar PMID:12629597 PMID:28492532 NCBI chr 5:1,225,381...1,246,189
Ensembl chr 5:1,225,381...1,246,189 		JBrowse link
G SLC6A19 solute carrier family 6 member 19 IAGP ClinVar Annotator: match by term: Interstitial lung disease 2 ClinVar PMID:12629597 PMID:28492532 NCBI chr 5:1,201,595...1,225,111
Ensembl chr 5:1,201,595...1,225,111 		JBrowse link
G SLC9A3 solute carrier family 9 member A3 IAGP ClinVar Annotator: match by term: Interstitial lung disease 2 ClinVar PMID:12629597 PMID:28492532 NCBI chr 5:470,456...524,449
Ensembl chr 5:470,456...524,449 		JBrowse link
G SMAD2 SMAD family member 2 IEP mRNA:increased expression:blood plasma (human) RGD PMID:31874165 RGD:152995482 NCBI chr18:47,808,957...47,930,872
Ensembl chr18:47,808,957...47,931,146 		JBrowse link
G SMAD6 SMAD family member 6 IEP mRNA:decreased expression:blood plasma (human) RGD PMID:31874165 RGD:152995482 NCBI chr15:66,702,236...66,782,849
Ensembl chr15:66,702,236...66,782,849 		JBrowse link
G ST14 ST14 transmembrane serine protease matriptase EXP CTD Direct Evidence: marker/mechanism CTD PMID:26599507 NCBI chr11:130,159,782...130,210,362
Ensembl chr11:130,159,782...130,210,362 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 IEP
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:30481203 PMID:22684844 RGD:6892915 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568 		JBrowse link
G STN1 STN1 subunit of CST complex EXP CTD Direct Evidence: marker/mechanism CTD PMID:23583980 NCBI chr10:103,877,569...103,918,184
Ensembl chr10:103,856,806...103,918,332 		JBrowse link
G TERC telomerase RNA component IAGP
EXP		 ClinVar Annotator: match by term: Interstitial lung disease 2
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD		 PMID:17392301 PMID:17460043 PMID:23535734 NCBI chr 3:169,764,610...169,765,060
Ensembl chr 3:169,764,610...169,765,047
Ensembl chr 3:169,764,610...169,765,047 		JBrowse link
G TERT telomerase reverse transcriptase IAGP
EXP		 DNA:deletion, missense mutations, splice-site mutations:multiple
ClinVar Annotator: match by term: Idiopathic Pulmonary Fibrosis
ClinVar Annotator: match by term: Idiopathic Pulmonary Fibrosis | ClinVar Annotator: match by term: Idiopathic fibrosing alveolitis, chronic form | ClinVar Annotator: match by term: Interstitial lung disease 2
ClinVar Annotator: match by term: Idiopathic Pulmonary Fibrosis | ClinVar Annotator: match by term: Interstitial lung disease 2
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
RGD		 PMID:9536098 PMID:12629597 PMID:15814878 PMID:15885610 PMID:16199547 More... RGD:11038666 NCBI chr 5:1,253,167...1,295,068
Ensembl chr 5:1,253,147...1,295,068 		JBrowse link
G TFPI tissue factor pathway inhibitor severity IEP protein:increased expression:Bronchoalveolar lavage,epithelial cell: RGD PMID:10946084 RGD:11060143 NCBI chr 2:187,464,230...187,554,435
Ensembl chr 2:187,464,230...187,565,760 		JBrowse link
G THBD thrombomodulin severity IEP RGD PMID:20418386 RGD:5685036 NCBI chr20:23,045,633...23,049,672
Ensembl chr20:23,045,633...23,049,672 		JBrowse link
G TNF tumor necrosis factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:8473757 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TOLLIP toll interacting protein IAGP ClinVar Annotator: match by term: Interstitial lung disease 2 ClinVar NCBI chr11:1,274,371...1,309,632
Ensembl chr11:1,274,371...1,309,654 		JBrowse link
G TPPP tubulin polymerization promoting protein IAGP ClinVar Annotator: match by term: Interstitial lung disease 2 ClinVar PMID:12629597 PMID:28492532 NCBI chr 5:659,862...700,727
Ensembl chr 5:659,862...693,352 		JBrowse link
G TRIP13 thyroid hormone receptor interactor 13 IAGP ClinVar Annotator: match by term: Interstitial lung disease 2 ClinVar PMID:12629597 PMID:28492532 NCBI chr 5:892,884...919,348
Ensembl chr 5:892,884...919,357 		JBrowse link
G WNT5A Wnt family member 5A EXP CTD Direct Evidence: marker/mechanism CTD PMID:28726637 NCBI chr 3:55,465,715...55,505,263
Ensembl chr 3:55,465,715...55,490,539 		JBrowse link
G ZDHHC11 zinc finger DHHC-type containing 11 IAGP ClinVar Annotator: match by term: Interstitial lung disease 2 ClinVar PMID:12629597 PMID:28492532 NCBI chr 5:795,605...860,563
Ensembl chr 5:795,605...858,973 		JBrowse link
G ZDHHC11B zinc finger DHHC-type containing 11B IAGP ClinVar Annotator: match by term: Interstitial lung disease 2 ClinVar PMID:12629597 PMID:28492532 NCBI chr 5:710,355...784,729
Ensembl chr 5:710,355...784,729 		JBrowse link
influenza A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATM ATM serine/threonine kinase exacerbates ISO RGD PMID:31509427 RGD:126779564 NCBI chr11:108,223,067...108,369,102
Ensembl chr11:108,222,823...108,369,102 		JBrowse link
G BTK Bruton tyrosine kinase ameliorates ISO Associated with Acute Lung Injury RGD PMID:29516781 RGD:124713566 NCBI chr  X:101,349,450...101,390,796
Ensembl chr  X:101,349,338...101,390,796 		JBrowse link
G DUOX1 dual oxidase 1 IEP protein:decreased expression:blood plasma (human) RGD PMID:24888898 RGD:40903071 NCBI chr15:45,129,994...45,165,574
Ensembl chr15:45,129,933...45,165,576 		JBrowse link
G DUOX2 dual oxidase 2 severity ISO RGD PMID:28936773 PMID:25751630 PMID:29556357 RGD:40924644, RGD:40925925, RGD:40925921 NCBI chr15:45,092,650...45,114,172
Ensembl chr15:45,092,650...45,114,172 		JBrowse link
G FAM157A family with sequence similarity 157 member A IEP protein:increased expression:blood plasma (human) RGD PMID:24888898 RGD:40903071 NCBI chr 3:198,153,206...198,222,513
Ensembl chr 3:198,180,755...198,190,365 		JBrowse link
G IFIH1 interferon induced with helicase C domain 1 ISO mRNA:increased expression:nasal cavity mucosa (mouse) RGD PMID:25751630 RGD:40925925 NCBI chr 2:162,267,074...162,318,684
Ensembl chr 2:162,267,074...162,318,684 		JBrowse link
G IL21 interleukin 21 ISO RGD PMID:25251568 RGD:127285548 NCBI chr 4:122,610,108...122,621,066
Ensembl chr 4:122,610,108...122,621,066 		JBrowse link
G IL27 interleukin 27 IEP protein:increased expression:blood serum (human) RGD PMID:22343630 RGD:126790513 NCBI chr16:28,499,362...28,506,834
Ensembl chr16:28,499,362...28,512,051 		JBrowse link
G IL32 interleukin 32 IEP protein:increased expression:blood serum (human) RGD PMID:22277801 PMID:19291698 PMID:18414668 RGD:150340718, RGD:150340751, RGD:150340729 NCBI chr16:3,065,403...3,069,530
Ensembl chr16:3,065,297...3,082,192 		JBrowse link
G KIR3DS1 killer cell immunoglobulin like receptor, three Ig domains and short cytoplasmic tail 1 exacerbates IAGP DNA:deletion: (human) RGD PMID:22652695 RGD:150340578
G MAP3K8 mitogen-activated protein kinase kinase kinase 8 exacerbates ISO RGD PMID:26241898 RGD:11055126 NCBI chr10:30,434,021...30,461,833
Ensembl chr10:30,434,021...30,461,833 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 ameliorates ISO RGD PMID:22514650 RGD:150340681 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360 		JBrowse link
G MARCO macrophage receptor with collagenous structure ameliorates ISO RGD PMID:21562316 RGD:41412197 NCBI chr 2:118,942,194...118,994,660
Ensembl chr 2:118,942,194...118,994,660 		JBrowse link
G MAVS mitochondrial antiviral signaling protein disease_progression ISO RGD PMID:27438481 RGD:40903047 NCBI chr20:3,846,834...3,876,118
Ensembl chr20:3,846,799...3,876,123 		JBrowse link
G MIR146A microRNA 146a exacerbates
ameliorates		 ISO RGD PMID:31638222 PMID:30611999 RGD:126925152, RGD:126925153 NCBI chr 5:160,485,352...160,485,450
Ensembl chr 5:160,485,352...160,485,450 		JBrowse link
G MX1 MX dynamin like GTPase 1 ameliorates ISO
IMP		 fused with PTD 9-arginine sequence
human gene in a mouse model		 RGD PMID:30696001 PMID:31653718 PMID:1371172 PMID:30945621 RGD:126777671, RGD:126777680, RGD:126777676, RGD:126777673 NCBI chr21:41,420,558...41,459,214
Ensembl chr21:41,420,020...41,470,071 		JBrowse link
G PLAC8 placenta associated 8 ISO RGD PMID:32639988 RGD:40925929 NCBI chr 4:83,090,048...83,114,729
Ensembl chr 4:83,090,048...83,137,075 		JBrowse link
G PPIA peptidylprolyl isomerase A ameliorates IMP human gene in a mouse model RGD PMID:27354005 RGD:150429624 NCBI chr 7:44,796,681...44,803,117
Ensembl chr 7:44,796,680...44,824,564 		JBrowse link
G RIGI RNA sensor RIG-I ISO mRNA:increased expression:nasal cavity mucosa (mouse) RGD PMID:25751630 RGD:40925925 NCBI chr 9:32,455,302...32,526,196
Ensembl chr 9:32,455,302...32,526,208 		JBrowse link
G RIPK3 receptor interacting serine/threonine kinase 3 exacerbates
susceptibility		 ISO RGD PMID:27321907 PMID:32200799 PMID:28410401 RGD:127229911, RGD:127229922, RGD:127229918 NCBI chr14:24,336,025...24,339,991
Ensembl chr14:24,336,025...24,340,022 		JBrowse link
G SAA1 serum amyloid A1 IEP protein:increased expression:blood plasma (human) RGD PMID:24888898 RGD:40903071 NCBI chr11:18,266,264...18,269,967
Ensembl chr11:18,266,260...18,269,977 		JBrowse link
G STAT2 signal transducer and activator of transcription 2 exacerbates ISO RGD PMID:30337919 RGD:41789626 NCBI chr12:56,341,597...56,360,107
Ensembl chr12:56,341,597...56,360,203 		JBrowse link
invasive aspergillosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGER advanced glycosylation end-product specific receptor ISO RGD PMID:21423669 RGD:5508765 NCBI chr 6:32,180,969...32,184,253
Ensembl chr 6:32,180,968...32,184,322 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 severity ISO RGD PMID:11160230 RGD:11528533 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CCL20 C-C motif chemokine ligand 20 ISO protein:increased expression:lung RGD PMID:20926800 RGD:7483599 NCBI chr 2:227,813,842...227,817,556
Ensembl chr 2:227,805,739...227,817,564 		JBrowse link
G CCR6 C-C motif chemokine receptor 6 disease_progression ISO RGD PMID:17379855 RGD:7483617 NCBI chr 6:167,111,795...167,139,141
Ensembl chr 6:167,111,807...167,139,141 		JBrowse link
G CXCR3 C-X-C motif chemokine receptor 3 IEP RGD PMID:17298426 RGD:5135501 NCBI chr  X:71,615,919...71,618,511
Ensembl chr  X:71,615,916...71,618,511 		JBrowse link
G CYBB cytochrome b-245 beta chain ISO RGD PMID:24054721 RGD:10450528 NCBI chr  X:37,780,059...37,813,461
Ensembl chr  X:37,780,018...37,813,461 		JBrowse link
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 treatment IAGP DNA:polymorphisms:cds: RGD PMID:26861072 RGD:124713410 NCBI chr10:94,762,681...94,855,547
Ensembl chr10:94,762,681...94,855,547 		JBrowse link
G ELANE elastase, neutrophil expressed ISO RGD PMID:24054721 RGD:10450528 NCBI chr19:852,303...856,243
Ensembl chr19:851,014...856,247 		JBrowse link
G IL17A interleukin 17A severity ISO RGD PMID:21807912 RGD:8698654 NCBI chr 6:52,186,375...52,190,638
Ensembl chr 6:52,186,375...52,190,638 		JBrowse link
G MBL2 mannose binding lectin 2 IAGP DNA:SNP:exon:rs5030737(human) RGD PMID:17311505 RGD:8693758 NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784 		JBrowse link
G PTX3 pentraxin 3 severity IAGP
IEP		 DNA:SNPs, missense mutation:intron, cds:rs2305619, rs1840680, rs3816527
protein:increased expression:bronchoalveolar lavage fluid (human)		 RGD PMID:30275011 PMID:28487045 RGD:38501097, RGD:38508892 NCBI chr 3:157,436,850...157,443,633
Ensembl chr 3:157,436,850...157,443,633 		JBrowse link
G S100B S100 calcium binding protein B ISO RGD PMID:21423669 RGD:5508765 NCBI chr21:46,598,604...46,605,082
Ensembl chr21:46,598,604...46,605,208 		JBrowse link
G TLR2 toll like receptor 2 ISO RGD PMID:16113258 RGD:8553022 NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,070...153,706,260 		JBrowse link
G TLR4 toll like receptor 4 susceptibility IAGP DNA:polymorphism:exon:p.D299G(human) RGD PMID:18275280 RGD:5130863 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
Invasive Pulmonary Aspergillosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL2 C-C motif chemokine ligand 2 treatment ISO RGD PMID:12917249 RGD:11528529 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CD209 CD209 molecule susceptibility IAGP DNA:SNPs:3'utr,intron:multiple RGD PMID:22384201 RGD:39938996 NCBI chr19:7,739,993...7,747,534
Ensembl chr19:7,739,993...7,747,564 		JBrowse link
G FGF2 fibroblast growth factor 2 treatment IDA RGD PMID:23303813 RGD:8655596 NCBI chr 4:122,826,682...122,898,236
Ensembl chr 4:122,826,682...122,898,236 		JBrowse link
G IL1A interleukin 1 alpha IAGP DNA:polymorphism, haplotype:promoter:-889C>T (human) RGD PMID:18484169 RGD:4142867 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493 		JBrowse link
G IL1B interleukin 1 beta IAGP DNA:polymorphism, haplotype: :-511C>T (human) RGD PMID:18484169 RGD:4142867 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G ITIH4 inter-alpha-trypsin inhibitor heavy chain 4 ISO protein:increased expression:respiratory system fluid/secretion, serum RGD PMID:24360996 RGD:40903005 NCBI chr 3:52,812,962...52,830,672
Ensembl chr 3:52,812,962...52,830,688 		JBrowse link
G MBL2 mannose binding lectin 2 treatment IDA RGD PMID:17335555 RGD:8693746 NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784 		JBrowse link
G PTX3 pentraxin 3 susceptibility
no_association		 IAGP
IEP		 DNA:SNP:intron:rs1840680 (human)
protein:increased expression:bronchoalveolar lavage fluid, plasma (human)
protein:increased expression:plasma
DNA:SNP, missense mutation:intron, cds:rs2305619, rs3816527		 RGD PMID:29020397 PMID:29964232 PMID:29020397 PMID:29020397 RGD:38501098, RGD:38508894, RGD:38501098, RGD:38501098 NCBI chr 3:157,436,850...157,443,633
Ensembl chr 3:157,436,850...157,443,633 		JBrowse link
G VEGFA vascular endothelial growth factor A treatment IDA RGD PMID:23303813 RGD:8655596 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487 		JBrowse link
Klebsiella pneumonia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CXCL8 C-X-C motif chemokine ligand 8 ISO RGD PMID:11207292 RGD:38549344 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G IL23A interleukin 23 subunit alpha severity ISO RGD PMID:16157683 RGD:39457940 NCBI chr12:56,338,884...56,340,410
Ensembl chr12:56,334,174...56,340,410 		JBrowse link
G IRAK3 interleukin 1 receptor associated kinase 3 severity ISO mRNA:increased expression:lung (mouse) RGD PMID:22729155 PMID:20864681 RGD:35316077, RGD:36049798 NCBI chr12:66,189,214...66,254,622
Ensembl chr12:66,189,195...66,254,622 		JBrowse link
G LCN2 lipocalin 2 exacerbates
ameliorates		 ISO protein:increased expression:lung
protein:increased expression:serum		 RGD PMID:29633303 PMID:19342674 PMID:19342674 PMID:19342674 PMID:25234944 More... RGD:126725082, RGD:126725085, RGD:126725085, RGD:126725085, RGD:126725084, RGD:126725084 NCBI chr 9:128,149,453...128,153,453
Ensembl chr 9:128,149,071...128,153,453 		JBrowse link
G PLAC8 placenta associated 8 severity ISO RGD PMID:17404296 RGD:40924563 NCBI chr 4:83,090,048...83,114,729
Ensembl chr 4:83,090,048...83,137,075 		JBrowse link
G TREM1 triggering receptor expressed on myeloid cells 1 disease_progression ISO RGD PMID:24396044 RGD:126925976 NCBI chr 6:41,267,385...41,286,682
Ensembl chr 6:41,267,926...41,286,682 		JBrowse link
Legionnaires' disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase IEP protein:increased expression:serum RGD PMID:9255891 RGD:5128857 NCBI chr20:44,619,522...44,651,699
Ensembl chr20:44,584,896...44,652,252 		JBrowse link
G CX3CL1 C-X3-C motif chemokine ligand 1 ISO RGD PMID:16113250 RGD:4891897 NCBI chr16:57,372,490...57,385,044
Ensembl chr16:57,372,477...57,385,044 		JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 ISO mRNA, protein:increased expression:lung RGD PMID:11254553 RGD:5135252 NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308 		JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 ISO mRNA, protein:increased expression:lung RGD PMID:11254553 RGD:5135252 NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196 		JBrowse link
G CXCL5 C-X-C motif chemokine ligand 5 ISO mRNA, protein:increased expression:lung RGD PMID:11254553 RGD:5135252 NCBI chr 4:73,995,642...73,998,677
Ensembl chr 4:73,995,642...73,998,677 		JBrowse link
G CXCL6 C-X-C motif chemokine ligand 6 ISO mRNA, protein:increased expression:lung RGD PMID:11254553 RGD:5135252 NCBI chr 4:73,836,678...73,838,760
Ensembl chr 4:73,836,640...73,849,064 		JBrowse link
G CXCR2 C-X-C motif chemokine receptor 2 ISO RGD PMID:11254553 RGD:5135252 NCBI chr 2:218,125,294...218,137,251
Ensembl chr 2:218,125,289...218,137,251 		JBrowse link
G IFNG interferon gamma EXP CTD Direct Evidence: therapeutic CTD PMID:11349020 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IL18 interleukin 18 ISO RGD PMID:11083766 RGD:4889865 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096 		JBrowse link
G MBL2 mannose binding lectin 2 susceptibility IEP RGD PMID:19073229 RGD:12910934 NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784 		JBrowse link
G NOD1 nucleotide binding oligomerization domain containing 1 ISO RGD PMID:20685341 RGD:5131443 NCBI chr 7:30,424,527...30,478,784
Ensembl chr 7:30,424,527...30,478,784 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 ISO RGD PMID:20685341 RGD:5131443 NCBI chr16:50,693,606...50,733,075
Ensembl chr16:50,693,588...50,733,077 		JBrowse link
G TLR5 toll like receptor 5 susceptibility IAGP
EXP
ISO		 DNA:nonsense mutation:cds:p.R392X (human)
ClinVar Annotator: match by term: Legionnaire disease, susceptibility to
CTD Direct Evidence: marker/mechanism		 ClinVar
OMIM
CTD
RGD		 PMID:14623910 PMID:16027372 PMID:23447684 PMID:25741868 PMID:14623910 More... RGD:5129477, RGD:5129510 NCBI chr 1:223,109,404...223,143,248
Ensembl chr 1:223,109,404...223,143,248 		JBrowse link
G TLR9 toll like receptor 9 ISO RGD PMID:18426877 RGD:5130707 NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,225,645 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A ISO RGD PMID:18838275 RGD:5131445 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114 		JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B ISO RGD PMID:18838275 RGD:5131445 NCBI chr 1:12,166,991...12,209,220
Ensembl chr 1:12,166,991...12,209,228 		JBrowse link
Mycoplasma pneumoniae pneumonia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase IEP protein:increased expression:serum RGD PMID:9255891 RGD:5128857 NCBI chr20:44,619,522...44,651,699
Ensembl chr20:44,584,896...44,652,252 		JBrowse link
G ATP1B2 ATPase Na+/K+ transporting subunit beta 2 severity HEP RGD PMID:28302172 RGD:32716376 NCBI chr17:7,646,627...7,657,770
Ensembl chr17:7,646,627...7,657,770 		JBrowse link
G CCL4 C-C motif chemokine ligand 4 ISO RGD PMID:16988274 RGD:4892091 NCBI chr17:36,103,827...36,105,614
Ensembl chr17:36,103,827...36,105,621 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 ISO protein:increased secretion:lung, secretion (mouse) RGD PMID:18717637 RGD:4891914 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793 		JBrowse link
G CCL8 C-C motif chemokine ligand 8 ISO RGD PMID:16988274 RGD:4892091 NCBI chr17:34,319,435...34,321,402
Ensembl chr17:34,319,435...34,321,402 		JBrowse link
G CCR5 C-C motif chemokine receptor 5 ISO protein:increased expression:lung, T-helper cell (mouse) RGD PMID:16988274 RGD:4892091 NCBI chr 3:46,370,142...46,376,206
Ensembl chr 3:46,370,946...46,376,206 		JBrowse link
G CLEC5A C-type lectin domain containing 5A severity HEP RGD PMID:28302172 RGD:32716376 NCBI chr 7:141,927,357...141,946,974
Ensembl chr 7:141,927,357...141,947,007 		JBrowse link
G COL3A1 collagen type III alpha 1 chain severity HEP RGD PMID:28302172 RGD:32716376 NCBI chr 2:188,974,373...189,012,746
Ensembl chr 2:188,974,373...189,012,746 		JBrowse link
G COL6A1 collagen type VI alpha 1 chain severity HEP RGD PMID:28302172 RGD:32716376 NCBI chr21:45,981,770...46,005,048
Ensembl chr21:45,981,770...46,005,050 		JBrowse link
G COL6A2 collagen type VI alpha 2 chain severity HEP RGD PMID:28302172 RGD:32716376 NCBI chr21:46,098,112...46,132,848
Ensembl chr21:46,098,112...46,132,848 		JBrowse link
G CRP C-reactive protein IEP RGD PMID:21426633 RGD:5131292 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589 		JBrowse link
G DNASE1L3 deoxyribonuclease 1L3 severity HEP RGD PMID:28302172 RGD:32716376 NCBI chr 3:58,192,257...58,210,972
Ensembl chr 3:58,192,257...58,214,697 		JBrowse link
G FCER2 Fc epsilon receptor II severity HEP RGD PMID:28302172 RGD:32716376 NCBI chr19:7,688,776...7,702,131
Ensembl chr19:7,688,758...7,702,146 		JBrowse link
G FLT1 fms related receptor tyrosine kinase 1 severity HEP RGD PMID:28302172 RGD:32716376 NCBI chr13:28,300,346...28,495,128
Ensembl chr13:28,300,346...28,495,145 		JBrowse link
G GALC galactosylceramidase IEP
ISO		 associated with Guillain-Barre syndrome; protein:increased expression:serum (human)
associated with Guillain-Barre syndrome; protein:increased expression:Cerebrospinal fluid, serum (human)
protein:increased expression:serum (mouse)		 RGD PMID:27490360 PMID:29301655 PMID:30396892 PMID:30396892 PMID:12225900 RGD:38599168, RGD:38599172, RGD:38599171, RGD:38599171, RGD:38599169 NCBI chr14:87,933,014...87,993,667
Ensembl chr14:87,837,820...87,993,665 		JBrowse link
G HDC histidine decarboxylase ISO RGD PMID:17158962 RGD:5143920 NCBI chr15:50,241,947...50,265,726
Ensembl chr15:50,241,947...50,265,965 		JBrowse link
G HTRA3 HtrA serine peptidase 3 severity HEP RGD PMID:28302172 RGD:32716376 NCBI chr 4:8,269,754...8,307,098
Ensembl chr 4:8,269,754...8,307,098 		JBrowse link
G IFNG interferon gamma ISO mRNA:increased expression:lung: RGD PMID:7935058 RGD:10755754 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IL13 interleukin 13 IEP protein:increased expression:serum RGD PMID:20416219 RGD:4145765 NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110 		JBrowse link
G IL22RA2 interleukin 22 receptor subunit alpha 2 severity HEP RGD PMID:28302172 RGD:32716376 NCBI chr 6:137,143,820...137,173,644
Ensembl chr 6:137,143,820...137,173,648 		JBrowse link
G INHBA inhibin subunit beta A severity HEP RGD PMID:28302172 RGD:32716376 NCBI chr 7:41,685,114...41,705,406
Ensembl chr 7:41,667,168...41,705,834 		JBrowse link
G KLRF1 killer cell lectin like receptor F1 severity HEP RGD PMID:28302172 RGD:32716376 NCBI chr12:9,800,052...9,845,005
Ensembl chr12:9,827,481...9,845,007 		JBrowse link
G MS4A1 membrane spanning 4-domains A1 severity HEP RGD PMID:28302172 RGD:32716376 NCBI chr11:60,455,847...60,470,752
Ensembl chr11:60,455,846...60,470,752 		JBrowse link
G PLD4 phospholipase D family member 4 severity HEP RGD PMID:28302172 RGD:32716376 NCBI chr14:104,924,879...104,937,785
Ensembl chr14:104,924,713...104,937,761 		JBrowse link
G SPIB Spi-B transcription factor severity HEP RGD PMID:28302172 RGD:32716376 NCBI chr19:50,418,938...50,431,314
Ensembl chr19:50,418,938...50,431,314 		JBrowse link
G TCF7 transcription factor 7 severity HEP RGD PMID:28302172 RGD:32716376 NCBI chr 5:134,108,218...134,148,210
Ensembl chr 5:134,114,681...134,151,865 		JBrowse link
G TCL1A TCL1 family AKT coactivator A severity HEP RGD PMID:28302172 RGD:32716376 NCBI chr14:95,709,947...95,714,125
Ensembl chr14:95,709,947...95,714,196 		JBrowse link
G TNF tumor necrosis factor IEP protein:increased expression:serum RGD PMID:20416219 RGD:4145765 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFRSF13C TNF receptor superfamily member 13C severity HEP RGD PMID:28302172 RGD:32716376 NCBI chr22:41,922,032...41,926,806
Ensembl chr22:41,922,032...41,926,806 		JBrowse link
nasopharyngitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTCH1 patched 1 IEP mRNA:decreased expression:epithelium of nasopharynx RGD PMID:23001130 RGD:150523839 NCBI chr 9:95,442,980...95,516,971
Ensembl chr 9:95,442,980...95,517,057 		JBrowse link
Perennial Allergic Rhinitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADIPOQ adiponectin, C1Q and collagen domain containing IEP protein:decreased expression:serum RGD PMID:19725899 RGD:5686851 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463 		JBrowse link
G ALB albumin EXP CTD Direct Evidence: marker/mechanism CTD PMID:19389874 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482 		JBrowse link
G ALOX5AP arachidonate 5-lipoxygenase activating protein IEP protein:increased expression:nasal turbinate RGD PMID:19364335 RGD:5147461 NCBI chr13:30,713,485...30,764,426
Ensembl chr13:30,713,478...30,764,426 		JBrowse link
G CAT catalase IEP protein:decreased expression:plasma RGD PMID:20493834 RGD:5130771 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 IEP protein:increased expression:nasal turbinate, mucosa (human) RGD PMID:9865755 RGD:8548839 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CCR2 C-C motif chemokine receptor 2 IEP mRNA:increased expression:Nasal Mucosa RGD PMID:17982926 RGD:4145109 NCBI chr 3:46,354,111...46,360,940
Ensembl chr 3:46,353,864...46,360,940 		JBrowse link
G CCR5 C-C motif chemokine receptor 5 IEP mRNA:increased expression:nasal mucosa (human) RGD PMID:17982926 RGD:4145109 NCBI chr 3:46,370,142...46,376,206
Ensembl chr 3:46,370,946...46,376,206 		JBrowse link
G CD40 CD40 molecule ISO RGD PMID:20226305 RGD:5132269 NCBI chr20:46,118,314...46,129,858
Ensembl chr20:46,118,271...46,129,863 		JBrowse link
G CD86 CD86 molecule IEP protein:increased expression:nasal mucosa, dendritic cell (human) RGD PMID:17088138 RGD:4892343 NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139 		JBrowse link
G CHIA chitinase acidic IEP mRNA, protein:increased expression:turbinate, mucosa (human) RGD PMID:20422678 RGD:5037226 NCBI chr 1:111,290,851...111,320,563
Ensembl chr 1:111,290,851...111,320,566 		JBrowse link
G EGR1 early growth response 1 IAGP DNA:snp:5' utr:g.-4071A>G rs7729723 (human) RGD PMID:19833116 RGD:5131984 NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303 		JBrowse link
G F2RL1 F2R like trypsin receptor 1 IEP RGD PMID:17727088 RGD:4892590 NCBI chr 5:76,819,030...76,835,315
Ensembl chr 5:76,818,933...76,835,315 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 susceptibility IAGP DNA:polymorphism:exon:p.I105V (rs1695) (human) RGD PMID:17181111 RGD:4142523 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656 		JBrowse link
G HMOX1 heme oxygenase 1 IEP mRNA, protein:increased expression: nasal mucosa RGD PMID:16540907 RGD:4145406 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO
IEP		 protein:increased expression:lung, endothelium (mouse)
protein:increased secretion:nasopharynx (human)		 RGD PMID:19968652 PMID:19047814 RGD:4145464, RGD:4145520 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615 		JBrowse link
G IFNGR1 interferon gamma receptor 1 IAGP DNA: SNP: Leu467Pro RGD PMID:12851715 RGD:6480431 NCBI chr 6:137,197,484...137,219,385
Ensembl chr 6:137,197,483...137,219,449 		JBrowse link
G IL13 interleukin 13 IEP mRNA, protein:increased expression:nasal mucosa RGD PMID:8520776 RGD:4782826 NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110 		JBrowse link
G IL17A interleukin 17A severity IEP protein:increased expression:serum RGD PMID:19226302 RGD:4889151 NCBI chr 6:52,186,375...52,190,638
Ensembl chr 6:52,186,375...52,190,638 		JBrowse link
G IL18 interleukin 18 susceptibility IAGP DNA:SNP:promoter:c. -607A>C (rs1946518) (human) RGD PMID:16406079 RGD:4889924 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096 		JBrowse link
G IL1A interleukin 1 alpha IAGP DNA:polymorphism:exon:c.4845G>T (human) RGD PMID:14533660 RGD:4142859 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493 		JBrowse link
G IL1R1 interleukin 1 receptor type 1 IDA RGD PMID:18637763 RGD:5037238 NCBI chr 2:102,070,390...102,179,874
Ensembl chr 2:102,064,544...102,179,874 		JBrowse link
G IL2 interleukin 2 IEP protein:decreased expression:serum: RGD PMID:17608155 RGD:8662959 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725 		JBrowse link
G IL4 interleukin 4 treatment IEP protein:increased expression:serum RGD PMID:21171297 PMID:9237816 PMID:15329007 RGD:5128559, RGD:7829817, RGD:7829804 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G IL5 interleukin 5 IEP protein: increased levels: sputum RGD PMID:22186238 RGD:5687140 NCBI chr 5:132,541,445...132,556,815
Ensembl chr 5:132,541,445...132,556,838 		JBrowse link
G MMP2 matrix metallopeptidase 2 IEP protein:increased expression:nasal mucosa: RGD PMID:19786210 RGD:5130872 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691 		JBrowse link
G MMP9 matrix metallopeptidase 9 IEP protein:increased expression:nasal mucosa: RGD PMID:19786210 RGD:5130872 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G NOS2 nitric oxide synthase 2 ISO protein:increased expression:nasal mucosa RGD PMID:14587983 RGD:4892078 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NOS3 nitric oxide synthase 3 IAGP DNA:snp:promoter:g.-786T>C (human) RGD PMID:18086269 RGD:4892054 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588 		JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 IEP protein:altered expression:nasal mucosa RGD PMID:20185258 RGD:4892593 NCBI chr 5:143,277,931...143,435,512
Ensembl chr 5:143,277,931...143,435,512 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma IEP mRNA, protein:increased expression:nasal mucosa (human) RGD PMID:17116814 RGD:8552811 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 IEP protein:increased expression:respiratory system epithelium RGD PMID:19364335 RGD:5147461 NCBI chr 9:122,370,533...122,395,703
Ensembl chr 9:122,370,530...122,395,703 		JBrowse link
G TBXA2R thromboxane A2 receptor treatment IMP RGD PMID:15247523 RGD:11059532 NCBI chr19:3,594,507...3,606,875
Ensembl chr19:3,594,507...3,606,875 		JBrowse link
pleural empyema term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLAU plasminogen activator, urokinase IDA Gene product used in treatment of disease RGD PMID:20304453 RGD:4891955 NCBI chr10:73,909,164...73,917,494
Ensembl chr10:73,909,177...73,917,496 		JBrowse link
G TNC tenascin C IEP protein:increased expression:pleura RGD PMID:10950882 RGD:4889594 NCBI chr 9:115,019,575...115,118,157
Ensembl chr 9:115,019,575...115,118,207 		JBrowse link
G TREM1 triggering receptor expressed on myeloid cells 1 treatment ISO RGD PMID:20819512 RGD:127284851 NCBI chr 6:41,267,385...41,286,682
Ensembl chr 6:41,267,926...41,286,682 		JBrowse link
pleural tuberculosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase IEP
IDA		 protein:increased activity:pleural fluid:
protein:increased activity:serum:
protein:increased expression:serum:		 RGD PMID:21860532 PMID:1818842 PMID:1689629 PMID:18357489 RGD:152995280, RGD:152998934, RGD:152995292, RGD:152995288 NCBI chr20:44,619,522...44,651,699
Ensembl chr20:44,584,896...44,652,252 		JBrowse link
G ADA2 adenosine deaminase 2 treatment IEP RGD PMID:8656037 RGD:152995258 NCBI chr22:17,178,790...17,221,848
Ensembl chr22:17,178,790...17,258,235 		JBrowse link
G CCL22 C-C motif chemokine ligand 22 IEP RGD PMID:20337996 RGD:4891473 NCBI chr16:57,357,909...57,366,189
Ensembl chr16:57,358,783...57,366,189 		JBrowse link
G CCR2 C-C motif chemokine receptor 2 IDA RGD PMID:19159432 RGD:4145106 NCBI chr 3:46,354,111...46,360,940
Ensembl chr 3:46,353,864...46,360,940 		JBrowse link
G CCR5 C-C motif chemokine receptor 5 IEP protein:increased expression:pleural fluid, natural killer cell (human) RGD PMID:19159432 RGD:4145106 NCBI chr 3:46,370,142...46,376,206
Ensembl chr 3:46,370,946...46,376,206 		JBrowse link
G FOXP3 forkhead box P3 disease_progression IEP associated with human immunodeficiency virus infectious disease; RGD PMID:21303360 RGD:36947878 NCBI chr  X:49,250,438...49,264,710
Ensembl chr  X:49,250,438...49,264,800 		JBrowse link
G IL1B interleukin 1 beta IAGP DNA:polymorphism: :3953T>C (human) RGD PMID:10377182 RGD:4143226 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL1RN interleukin 1 receptor antagonist IAGP DNA:repeat (human) RGD PMID:10377182 RGD:4143226 NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016 		JBrowse link
G IL27 interleukin 27 exacerbates IEP associated with Pleural Effusion;protein:increased expression:pleural fluid (human)
protein:increased expression:alveolar system (human)		 RGD PMID:25753767 PMID:31819557 PMID:23962500 PMID:28844060 RGD:126790505, RGD:126790549, RGD:126790523, RGD:126790517 NCBI chr16:28,499,362...28,506,834
Ensembl chr16:28,499,362...28,512,051 		JBrowse link
G IL33 interleukin 33 IEP protein:increased expression:pleural fluid: RGD PMID:23301222 RGD:39939042 NCBI chr 9:6,215,149...6,257,983
Ensembl chr 9:6,215,786...6,257,983 		JBrowse link
G MMP9 matrix metallopeptidase 9 IEP protein:increased expression:pleura: RGD PMID:18715875 RGD:5129700 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G TLR4 toll like receptor 4 IEP RGD PMID:18295348 RGD:4144193 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G TNC tenascin C IEP protein:increased expression:pleura RGD PMID:10950882 RGD:4889594 NCBI chr 9:115,019,575...115,118,157
Ensembl chr 9:115,019,575...115,118,207 		JBrowse link
pleurisy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase ISO RGD PMID:16860713 RGD:5128847 NCBI chr20:44,619,522...44,651,699
Ensembl chr20:44,584,896...44,652,252 		JBrowse link
G ALOX5 arachidonate 5-lipoxygenase ISO RGD PMID:9109363 RGD:4890429 NCBI chr10:45,374,216...45,446,117
Ensembl chr10:45,374,176...45,446,119 		JBrowse link
G ANXA1 annexin A1 ISO RGD PMID:15784654 RGD:2306907 NCBI chr 9:73,151,865...73,170,393
Ensembl chr 9:73,151,865...73,170,393 		JBrowse link
G BDKRB1 bradykinin receptor B1 ISO RGD PMID:11853231 RGD:5129218 NCBI chr14:96,256,210...96,264,763
Ensembl chr14:96,256,210...96,268,967 		JBrowse link
G BDKRB2 bradykinin receptor B2 ISO RGD PMID:15316088 PMID:9208140 RGD:4891029, RGD:4891041 NCBI chr14:96,204,839...96,244,164
Ensembl chr14:96,204,679...96,244,166 		JBrowse link
G C3 complement C3 ISO protein:increased activity:pleural cavity RGD PMID:18256172 RGD:5129520 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562 		JBrowse link
G CAT catalase ISO RGD PMID:19778612 RGD:5130749 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CCL11 C-C motif chemokine ligand 11 ISO protein:increased expression:pleural fluid RGD PMID:11877329 PMID:11564646 RGD:4145443, RGD:4145479 NCBI chr17:34,285,742...34,288,334
Ensembl chr17:34,285,742...34,288,334 		JBrowse link
G CCL25 C-C motif chemokine ligand 25 ISO protein:increased expression:pleural fluid RGD PMID:18056919 RGD:5130924 NCBI chr19:8,052,341...8,062,650
Ensembl chr19:8,052,318...8,062,660 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 ISO protein:increased secretion:lung (mouse) RGD PMID:18672096 RGD:4890016 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793 		JBrowse link
G CCR3 C-C motif chemokine receptor 3 ISO associated with Mycobacterium Infections RGD PMID:17158890 RGD:4145643 NCBI chr 3:46,210,696...46,266,706
Ensembl chr 3:46,130,890...46,266,706 		JBrowse link
G CSF3 colony stimulating factor 3 IDA RGD PMID:8841835 RGD:11039424 NCBI chr17:40,015,440...40,017,813
Ensembl chr17:40,015,361...40,017,813 		JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 ISO RGD PMID:14527170 RGD:5135449 NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308 		JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 ISO RGD PMID:14527170 RGD:5135449 NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497 		JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 ISO RGD PMID:21549112 PMID:14527170 RGD:5135064, RGD:5135449 NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196 		JBrowse link
G CXCL9 C-X-C motif chemokine ligand 9 ISO RGD PMID:14527170 RGD:5135449 NCBI chr 4:76,001,275...76,007,509
Ensembl chr 4:76,001,275...76,007,509 		JBrowse link
G EDNRA endothelin receptor type A ISO RGD PMID:15107459 RGD:4892325 NCBI chr 4:147,481,097...147,544,954
Ensembl chr 4:147,480,917...147,544,954 		JBrowse link
G ELANE elastase, neutrophil expressed ISO RGD PMID:20860667 RGD:10450565 NCBI chr19:852,303...856,243
Ensembl chr19:851,014...856,247 		JBrowse link
G ESR1 estrogen receptor 1 ISO RGD PMID:17035596 RGD:4892303 NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 IEP
EXP
ISO		 associated with Tuberculosis; protein:increased expression:pleural fluid, natural killer cell (human)
CTD Direct Evidence: marker/mechanism
protein:increased expression:bronchial epithelium (mouse)		 CTD
RGD		 PMID:11181422 PMID:19714575 PMID:19056932 RGD:4145510, RGD:4145519 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615 		JBrowse link
G IL10 interleukin 10 EXP CTD Direct Evidence: marker/mechanism CTD PMID:11181422 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL15 interleukin 15 IDA RGD PMID:10823416 RGD:4990464 NCBI chr 4:141,636,583...141,733,987
Ensembl chr 4:141,636,583...141,733,987 		JBrowse link
G IL17A interleukin 17A treatment ISO RGD PMID:21898269 RGD:7175307 NCBI chr 6:52,186,375...52,190,638
Ensembl chr 6:52,186,375...52,190,638 		JBrowse link
G IL1B interleukin 1 beta ISO
EXP		 CTD Direct Evidence: marker/mechanism
protein:increased expression:pleural cavity, exudate (rat)
protein:increased expression:lung		 CTD
RGD		 PMID:11181422 PMID:20141620 PMID:21898269 PMID:20175894 RGD:4142808, RGD:7175307, RGD:4142826 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL1RN interleukin 1 receptor antagonist IDA RGD PMID:8491511 RGD:4143233 NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016 		JBrowse link
G IL6 interleukin 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:11181422 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G MPO myeloperoxidase ISO protein:increased activity:lung RGD PMID:11577999 RGD:5130991 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 ISO RGD PMID:14673141 RGD:6893408 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NOS2 nitric oxide synthase 2 ISO protein:increased expression:pleural cavity (rat) RGD PMID:21898269 PMID:20141620 RGD:7175307, RGD:4142808 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G PLA2G6 phospholipase A2 group VI ISO RGD PMID:15003994 RGD:6482741 NCBI chr22:38,111,495...38,181,830
Ensembl chr22:38,111,495...38,214,778 		JBrowse link
G PTAFR platelet activating factor receptor treatment ISO RGD PMID:8395390 RGD:10043147 NCBI chr 1:28,147,166...28,193,856
Ensembl chr 1:28,147,166...28,193,936 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO RGD PMID:20141620 PMID:15740981 RGD:4142808, RGD:5143929 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G SELP selectin P ISO
EXP		 protein:increased expression:lung
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:11181422 PMID:21147071 RGD:6219005 NCBI chr 1:169,588,849...169,630,124
Ensembl chr 1:169,588,849...169,630,193 		JBrowse link
G SERPINE1 serpin family E member 1 susceptibility IAGP associated with Familial Mediterranean Fever;DNA: DNA:polymorphism:promoter:rs1799768 (human): RGD PMID:23052617 RGD:13207414 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247 		JBrowse link
G TNF tumor necrosis factor ISO
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:11181422 PMID:15380531 PMID:11161459 PMID:20141620 RGD:4143474, RGD:4142808 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFSF8 TNF superfamily member 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15380531 NCBI chr 9:114,893,343...114,930,595
Ensembl chr 9:114,893,343...114,930,595 		JBrowse link
pleuropneumonia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX5 arachidonate 5-lipoxygenase ISO RGD PMID:12773506 RGD:4890419 NCBI chr10:45,374,216...45,446,117
Ensembl chr10:45,374,176...45,446,119 		JBrowse link
Pneumococcal Pneumonia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AICDA activation induced cytidine deaminase ISO RGD PMID:26456931 RGD:11098923 NCBI chr12:8,602,170...8,612,859
Ensembl chr12:8,602,155...8,613,242 		JBrowse link
G ALOX5 arachidonate 5-lipoxygenase ISO RGD PMID:20231413 RGD:4890435 NCBI chr10:45,374,216...45,446,117
Ensembl chr10:45,374,176...45,446,119 		JBrowse link
G BTK Bruton tyrosine kinase ameliorates ISO RGD PMID:30646846 RGD:124715470 NCBI chr  X:101,349,450...101,390,796
Ensembl chr  X:101,349,338...101,390,796 		JBrowse link
G C3 complement C3 disease_progression ISO
IEP		 associated with Liver Cirrhosis, Experimental;protein:decreased expression:respiratory system fluid/secretion
protein:decreased expression:serum		 RGD PMID:17956621 PMID:15972516 PMID:20405 RGD:5129523, RGD:5129509, RGD:5130163 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562 		JBrowse link
G C5 complement C5 severity ISO RGD PMID:7814608 RGD:5130159 NCBI chr 9:120,952,335...121,074,865
Ensembl chr 9:120,932,987...121,075,195 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 susceptibility ISO RGD PMID:16455992 RGD:4892130 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793 		JBrowse link
G CD14 CD14 molecule ISO RGD PMID:17185649 RGD:4144788 NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,700 		JBrowse link
G CHI3L1 chitinase 3 like 1 IEP protein:increased secretion:serum (human) RGD PMID:10515841 RGD:4892626 NCBI chr 1:203,178,931...203,186,704
Ensembl chr 1:203,178,931...203,186,704 		JBrowse link
G CRHR1 corticotropin releasing hormone receptor 1 ISO RGD PMID:21774994 RGD:5147472 NCBI chr17:45,784,320...45,835,828
Ensembl chr17:45,784,277...45,835,828 		JBrowse link
G CRHR2 corticotropin releasing hormone receptor 2 ISO RGD PMID:21774994 RGD:5147472 NCBI chr 7:30,651,942...30,700,103
Ensembl chr 7:30,651,942...30,700,129 		JBrowse link
G CRP C-reactive protein disease_progression IEP RGD PMID:21281676 RGD:5131293 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589 		JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 ISO protein:increased expression:respiratory system fluid/secretion RGD PMID:20958976 RGD:5134957 NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24894820 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CXCL9 C-X-C motif chemokine ligand 9 ISO protein:increased expression:lung RGD PMID:20381636 RGD:5135285 NCBI chr 4:76,001,275...76,007,509
Ensembl chr 4:76,001,275...76,007,509 		JBrowse link
G DEFB4A defensin beta 4A EXP CTD Direct Evidence: marker/mechanism CTD PMID:24894820 NCBI chr 8:7,894,677...7,896,716
Ensembl chr 8:7,894,677...7,896,716
Ensembl chr 8:7,894,677...7,896,716 		JBrowse link
G HMOX1 heme oxygenase 1 ISO associated with influenza;protein:increased expression:lung RGD PMID:17348295 RGD:4145366 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HP haptoglobin IEP RGD PMID:19396720 RGD:5147385 NCBI chr16:72,054,505...72,061,055
Ensembl chr16:72,054,505...72,061,055 		JBrowse link
G IL15 interleukin 15 ISO protein:increased expression:alveolar macrophage, bronchial epithelial cell RGD PMID:17611121 RGD:5000755 NCBI chr 4:141,636,583...141,733,987
Ensembl chr 4:141,636,583...141,733,987 		JBrowse link
G IL15RA interleukin 15 receptor subunit alpha ISO RGD PMID:17611121 RGD:5000755 NCBI chr10:5,948,900...5,978,741
Ensembl chr10:5,943,639...5,978,187 		JBrowse link
G IL17A interleukin 17A ISO RGD PMID:19995896 RGD:4888531 NCBI chr 6:52,186,375...52,190,638
Ensembl chr 6:52,186,375...52,190,638 		JBrowse link
G IL18 interleukin 18 ISO RGD PMID:15770015 RGD:4889960 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096 		JBrowse link
G IL6 interleukin 6 ISO RGD PMID:20643849 RGD:4143255 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G LEP leptin ISO RGD PMID:17822444 RGD:5128869 NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629 		JBrowse link
G LEPR leptin receptor ISO RGD PMID:21148797 RGD:5128846 NCBI chr 1:65,420,652...65,641,559
Ensembl chr 1:65,420,652...65,641,559 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24894820 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24894820 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MASP2 MBL associated serine protease 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:12904520 NCBI chr 1:11,026,523...11,047,239
Ensembl chr 1:11,022,009...11,047,239 		JBrowse link
G MBL2 mannose binding lectin 2 no_association IAGP DNA:polymorphisms:5' utr, exon:multiple (human)
DNA:mutations:5' utr, exon:multiple (human)		 RGD PMID:12047967 PMID:18641104 RGD:4889478, RGD:4889477 NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784 		JBrowse link
G NOS2 nitric oxide synthase 2 ISO RGD PMID:17056580 RGD:4891950 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G PTEN phosphatase and tensin homolog ameliorates ISO myeloid knockout RGD PMID:20505137 RGD:127285597 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930 		JBrowse link
G SFTPD surfactant protein D severity ISO RGD PMID:16255775 RGD:4143519 NCBI chr10:79,937,740...79,982,383
Ensembl chr10:79,937,467...79,982,614 		JBrowse link
G SIRT1 sirtuin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24894820 NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390 		JBrowse link
G STING1 stimulator of interferon response cGAMP interactor 1 ISO RGD PMID:29263110 RGD:39128230 NCBI chr 5:139,475,533...139,482,758
Ensembl chr 5:139,475,533...139,482,935 		JBrowse link
G TLR2 toll like receptor 2 ISO RGD PMID:19956717 RGD:4145321 NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,070...153,706,260 		JBrowse link
G TNF tumor necrosis factor ISO associated with influenza;protein:increased expression:lung RGD PMID:9032201 PMID:17348295 RGD:4143479, RGD:4145366 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TREM1 triggering receptor expressed on myeloid cells 1 ameliorates ISO RGD PMID:24752755 PMID:19596984 RGD:126928121, RGD:127229903 NCBI chr 6:41,267,385...41,286,682
Ensembl chr 6:41,267,926...41,286,682 		JBrowse link
pneumocystosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AZIN1 antizyme inhibitor 1 ISO mRNA:increased expression:alveolar macrophage RGD PMID:19158080 RGD:14700806 NCBI chr 8:102,826,302...102,864,200
Ensembl chr 8:102,826,111...102,893,864 		JBrowse link
G C3 complement C3 ISO RGD PMID:17169032 RGD:5129525 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 IEP protein:increased expression:respiratory system fluid/secretion RGD PMID:20618689 RGD:4891428 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CD40 CD40 molecule treatment ISO RGD PMID:10968950 RGD:8547797 NCBI chr20:46,118,314...46,129,858
Ensembl chr20:46,118,271...46,129,863 		JBrowse link
G CSF2 colony stimulating factor 2 ISO protein:increased expression:respiratory system fluid/secretion RGD PMID:19487471 RGD:5131475 NCBI chr 5:132,073,789...132,076,170
Ensembl chr 5:132,073,789...132,076,170 		JBrowse link
G HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 ISO RGD PMID:20377877 RGD:4144112 NCBI chr 6:32,659,467...32,666,657
Ensembl chr 6:32,659,467...32,668,383 		JBrowse link
G IL23A interleukin 23 subunit alpha ISO RGD PMID:17403873 RGD:39458043 NCBI chr12:56,338,884...56,340,410
Ensembl chr12:56,334,174...56,340,410 		JBrowse link
G IL33 interleukin 33 treatment ISO RGD PMID:21220696 RGD:40400892 NCBI chr 9:6,215,149...6,257,983
Ensembl chr 9:6,215,786...6,257,983 		JBrowse link
G MUC1 mucin 1, cell surface associated IEP protein:increased expression:serum RGD PMID:9617869 RGD:5131424 NCBI chr 1:155,185,824...155,192,915
Ensembl chr 1:155,185,824...155,192,916 		JBrowse link
G NOS2 nitric oxide synthase 2 ISO protein:decreased dimerization:alveolar macrophage
mRNA:increased expression:alveolar macrophage		 RGD PMID:20558778 PMID:20377877 RGD:4891486, RGD:4144112 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G SFTPA1 surfactant protein A1 ISO protein:increased expression:lung RGD PMID:11385364 RGD:4143431 NCBI chr10:79,610,939...79,615,455
Ensembl chr10:79,610,939...79,615,455 		JBrowse link
G SFTPB surfactant protein B ISO protein:decreased expression:lung RGD PMID:11385364 RGD:4143431 NCBI chr 2:85,657,307...85,668,741
Ensembl chr 2:85,657,314...85,668,741 		JBrowse link
G SFTPC surfactant protein C ISO protein:decreased expression:lung RGD PMID:11385364 RGD:4143431 NCBI chr 8:22,157,383...22,164,479
Ensembl chr 8:22,156,913...22,164,479 		JBrowse link
G SFTPD surfactant protein D ISO protein:increased expression:lung RGD PMID:11385364 RGD:4143431 NCBI chr10:79,937,740...79,982,383
Ensembl chr10:79,937,467...79,982,614 		JBrowse link
G TLR2 toll like receptor 2 ISO RGD PMID:18400546 RGD:4145341 NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,070...153,706,260 		JBrowse link
pneumonia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCF1 ATP binding cassette subfamily F member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 6:30,571,442...30,591,522
Ensembl chr 6:30,571,393...30,597,179 		JBrowse link
G ABO ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase severity IAGP DNA:polymorphism:cds:allele A (human) RGD PMID:4375858 RGD:39938844 NCBI chr 9:133,250,401...133,275,201
Ensembl chr 9:133,233,278...133,276,024 		JBrowse link
G ACE angiotensin I converting enzyme disease_progression IEP
IMP		 associated with Hypertension RGD PMID:17727310 PMID:20051911 PMID:19455553 RGD:4140922, RGD:4140916, RGD:4140918 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380 		JBrowse link
G ADORA1 adenosine A1 receptor ISO RGD PMID:15630442 RGD:5129098 NCBI chr 1:203,127,726...203,167,405
Ensembl chr 1:203,090,654...203,167,405 		JBrowse link
G ADORA2A adenosine A2a receptor ISO associated with Lung Injury
associated with Anemia, Sickle Cell		 RGD PMID:18703794 PMID:17601796 PMID:20798237 RGD:4890364, RGD:4890376, RGD:4890358 NCBI chr22:24,423,597...24,442,357
Ensembl chr22:24,417,879...24,442,357 		JBrowse link
G ADRB2 adrenoceptor beta 2 ISO RGD PMID:19925785 RGD:4145041 NCBI chr 5:148,826,611...148,828,623
Ensembl chr 5:148,826,611...148,828,623 		JBrowse link
G AGT angiotensinogen EXP CTD Direct Evidence: therapeutic CTD PMID:28960804 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576 		JBrowse link
G AHR aryl hydrocarbon receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:23337360 NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152 		JBrowse link
G ALB albumin disease_progression IEP RGD PMID:23286966 RGD:11035283 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482 		JBrowse link
G BDKRB2 bradykinin receptor B2 ISO RGD PMID:15021973 RGD:4891030 NCBI chr14:96,204,839...96,244,164
Ensembl chr14:96,204,679...96,244,166 		JBrowse link
G C3 complement C3 ISO RGD PMID:10886251 RGD:5129562 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562 		JBrowse link
G C3AR1 complement C3a receptor 1 ISO associated with Respiratory Syncytial Virus Infections RGD PMID:17079327 RGD:5129688 NCBI chr12:8,056,844...8,066,359
Ensembl chr12:8,056,844...8,066,359 		JBrowse link
G C5 complement C5 IDA
ISO		 associated with Respiratory Syncytial Virus Infections RGD PMID:3631740 PMID:17079327 RGD:5130161, RGD:5129688 NCBI chr 9:120,952,335...121,074,865
Ensembl chr 9:120,932,987...121,075,195 		JBrowse link
G CASP1 caspase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250 		JBrowse link
G CCL11 C-C motif chemokine ligand 11 ISO
EXP		 mRNA, protein:increased expression:lung, respiratory system fluid/secretion
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:21625544 PMID:11290805 PMID:10595930 RGD:4145445, RGD:4145450 NCBI chr17:34,285,742...34,288,334
Ensembl chr17:34,285,742...34,288,334 		JBrowse link
G CCL13 C-C motif chemokine ligand 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr17:34,356,480...34,358,610
Ensembl chr17:34,356,480...34,358,610 		JBrowse link
G CCL17 C-C motif chemokine ligand 17 ISO
EXP		 mRNA:increased expression:lung
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:21625544 PMID:15993846 RGD:2306304 NCBI chr16:57,396,093...57,416,063
Ensembl chr16:57,404,767...57,416,063 		JBrowse link
G CCL19 C-C motif chemokine ligand 19 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 9:34,689,570...34,691,276
Ensembl chr 9:34,689,570...34,691,276 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 ISO
EXP		 protein:increased expression:respiratory system fluid/secretion
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:21625544 PMID:19648283 RGD:4891461 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CCL20 C-C motif chemokine ligand 20 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 2:227,813,842...227,817,556
Ensembl chr 2:227,805,739...227,817,564 		JBrowse link
G CCL22 C-C motif chemokine ligand 22 ISO mRNA:increased expression:lung RGD PMID:15993846 RGD:2306304 NCBI chr16:57,357,909...57,366,189
Ensembl chr16:57,358,783...57,366,189 		JBrowse link
G CCL23 C-C motif chemokine ligand 23 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr17:36,013,058...36,017,972
Ensembl chr17:36,013,056...36,017,972 		JBrowse link
G CCL24 C-C motif chemokine ligand 24 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 7:75,810,825...75,823,372
Ensembl chr 7:75,810,825...75,823,356 		JBrowse link
G CCL3 C-C motif chemokine ligand 3 HEP mRNA:increased expression:bronchoalveolar lavage (human) RGD PMID:32407669 RGD:30296672 NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169 		JBrowse link
G CCL4 C-C motif chemokine ligand 4 EXP
HEP		 CTD Direct Evidence: marker/mechanism
mRNA:increased expression:bronchoalveolar lavage (human)		 CTD
RGD		 PMID:21625544 PMID:32407669 RGD:30296672 NCBI chr17:36,103,827...36,105,614
Ensembl chr17:36,103,827...36,105,621 		JBrowse link
G CCL7 C-C motif chemokine ligand 7 IEP
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:21625544 PMID:15191918 RGD:5130985 NCBI chr17:34,270,221...34,272,242
Ensembl chr17:34,270,221...34,272,242 		JBrowse link
G CCL8 C-C motif chemokine ligand 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr17:34,319,435...34,321,402
Ensembl chr17:34,319,435...34,321,402 		JBrowse link
G CCR1 C-C motif chemokine receptor 1 ISO
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:21625544 PMID:20870892 RGD:5688175 NCBI chr 3:46,201,711...46,208,313
Ensembl chr 3:46,201,711...46,208,313 		JBrowse link
G CCR2 C-C motif chemokine receptor 2 ISO
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:21625544 PMID:14615370 PMID:17284325 RGD:4145068, RGD:8661704 NCBI chr 3:46,354,111...46,360,940
Ensembl chr 3:46,353,864...46,360,940 		JBrowse link
G CCR3 C-C motif chemokine receptor 3 ISO mRNA:increased expression:lung RGD PMID:19762220 RGD:4145622 NCBI chr 3:46,210,696...46,266,706
Ensembl chr 3:46,130,890...46,266,706 		JBrowse link
G CCR5 C-C motif chemokine receptor 5 ISO Idiopathic Pneumonia Syndrome; mRNA:increased expression:lung (mouse) RGD PMID:15546955 RGD:4892103 NCBI chr 3:46,370,142...46,376,206
Ensembl chr 3:46,370,946...46,376,206 		JBrowse link
G CCR6 C-C motif chemokine receptor 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 6:167,111,795...167,139,141
Ensembl chr 6:167,111,807...167,139,141 		JBrowse link
G CCR7 C-C motif chemokine receptor 7 IEP mRNA, protein:increased expression:lung RGD PMID:16394278 RGD:5130919 NCBI chr17:40,553,769...40,565,472
Ensembl chr17:40,553,769...40,565,472 		JBrowse link
G CCR9 C-C motif chemokine receptor 9 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 3:45,886,064...45,903,174
Ensembl chr 3:45,884,425...45,903,174 		JBrowse link
G CD14 CD14 molecule IEP protein:increased expression:multiple RGD PMID:20302606 RGD:4144794 NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,700 		JBrowse link
G CD163 CD163 molecule IEP associated with liver disease;protein:increased expression:blood serum (human) RGD PMID:26339412 RGD:11251207 NCBI chr12:7,470,811...7,503,777
Ensembl chr12:7,470,811...7,503,893 		JBrowse link
G CD40LG CD40 ligand EXP CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr  X:136,648,158...136,660,390
Ensembl chr  X:136,648,158...136,660,390 		JBrowse link
G CRHR2 corticotropin releasing hormone receptor 2 ISO RGD PMID:16855006 RGD:5130933 NCBI chr 7:30,651,942...30,700,103
Ensembl chr 7:30,651,942...30,700,129 		JBrowse link
G CRP C-reactive protein disease_progression
severity		 IEP RGD PMID:21439658 PMID:21258955 RGD:5131291, RGD:5131283 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589 		JBrowse link
G CSF2 colony stimulating factor 2 ISO
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:11732872 PMID:19633061 RGD:4142837 NCBI chr 5:132,073,789...132,076,170
Ensembl chr 5:132,073,789...132,076,170 		JBrowse link
G CSF3R colony stimulating factor 3 receptor HEP mRNA:increased expression:bronchoalveolar lavage (human) RGD PMID:32407669 RGD:30296672 NCBI chr 1:36,466,043...36,483,314
Ensembl chr 1:36,466,043...36,483,278 		JBrowse link
G CSK C-terminal Src kinase ISO RGD PMID:14975240 RGD:5134363 NCBI chr15:74,782,080...74,803,197
Ensembl chr15:74,782,080...74,803,197 		JBrowse link
G CX3CL1 C-X3-C motif chemokine ligand 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr16:57,372,490...57,385,044
Ensembl chr16:57,372,477...57,385,044 		JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 ISO
EXP		 mRNA, protein:increased expression:lung
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:21625544 PMID:20728373 RGD:5134959 NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308 		JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 ISO associated with Lupus Erythematosus, Systemic;mRNA:increased expression:lung RGD PMID:15265940 PMID:14979941 RGD:5135445, RGD:5135491 NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497 		JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 ISO mRNA, protein:increased expression:lung
mRNA:increased expression:lung		 RGD PMID:20728373 PMID:18367723 RGD:5134959, RGD:5135235 NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196 		JBrowse link
G CXCL5 C-X-C motif chemokine ligand 5 IEP
EXP		 protein:increased expression:sputum
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:21625544 PMID:18410262 RGD:5135259 NCBI chr 4:73,995,642...73,998,677
Ensembl chr 4:73,995,642...73,998,677 		JBrowse link
G CXCL6 C-X-C motif chemokine ligand 6 ISO mRNA:increased expression:lung RGD PMID:20650015 RGD:4892029 NCBI chr 4:73,836,678...73,838,760
Ensembl chr 4:73,836,640...73,849,064 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 ISO
HEP		 CTD Direct Evidence: marker/mechanism
mRNA:increased expression:bronchoalveolar lavage (human)		 CTD
RGD		 PMID:21625544 PMID:32407669 RGD:30296672 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CXCL9 C-X-C motif chemokine ligand 9 IEP
EXP
ISO		 protein:increased expression:serum
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:21625544 PMID:17052299 PMID:15265940 RGD:5135440, RGD:5135445 NCBI chr 4:76,001,275...76,007,509
Ensembl chr 4:76,001,275...76,007,509 		JBrowse link
G CXCR2 C-X-C motif chemokine receptor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 2:218,125,294...218,137,251
Ensembl chr 2:218,125,289...218,137,251 		JBrowse link
G CXCR3 C-X-C motif chemokine receptor 3 ISO
EXP		 CTD Direct Evidence: marker/mechanism
associated with Lupus Erythematosus, Systemic;mRNA:increased expression:lung		 CTD
RGD		 PMID:21625544 PMID:15265940 PMID:14979941 RGD:5135445, RGD:5135491 NCBI chr  X:71,615,919...71,618,511
Ensembl chr  X:71,615,916...71,618,511 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 susceptibility IAGP DNA:polymorphism (human) RGD PMID:15928955 RGD:4142512 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 ISO
IAGP		 protein:increased expression:alveolus, epithelial cell
DNA:polymorphism (human)		 RGD PMID:14698565 PMID:15928955 RGD:4892223, RGD:4142512 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220 		JBrowse link
G DEFB1 defensin beta 1 IEP protein:increased expression:serum RGD PMID:17000097 RGD:4892262 NCBI chr 8:6,870,592...6,877,936
Ensembl chr 8:6,870,592...6,877,936 		JBrowse link
G EDN1 endothelin 1 severity IEP protein:increased secretion:plasma (human) RGD PMID:20529344 RGD:4144879 NCBI chr 6:12,230,516...12,297,194
Ensembl chr 6:12,290,361...12,297,194 		JBrowse link
G EGF epidermal growth factor resistance ISO RGD PMID:21701422 RGD:6906904 NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766 		JBrowse link
G EGR1 early growth response 1 EXP CTD Direct Evidence: therapeutic CTD PMID:29787794 NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303 		JBrowse link
G FCGR3A Fc gamma receptor IIIa treatment IAGP associated with Hodgkin Disease;DNA:SNP:exon:p.F158V (rs396991) (human) RGD PMID:20423913 RGD:11352258 NCBI chr 1:161,541,759...161,550,737
Ensembl chr 1:161,541,759...161,550,968 		JBrowse link
G GRP gastrin releasing peptide IEP protein:increased expression:serum (human) RGD PMID:30146822 RGD:401700396 NCBI chr18:59,219,189...59,230,771
Ensembl chr18:59,220,158...59,230,774 		JBrowse link
G HDC histidine decarboxylase ISO RGD PMID:14556983 RGD:5143922 NCBI chr15:50,241,947...50,265,726
Ensembl chr15:50,241,947...50,265,965 		JBrowse link
G HMOX1 heme oxygenase 1 susceptibility IAGP
EXP		 DNA:allele:promoter:L allele of the (GT)n repeat (>30 repeats)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:16582079 PMID:16582079 RGD:1601608 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 treatment ISO associated with Reperfusion Injury RGD PMID:22882462 RGD:8547727 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615 		JBrowse link
G IFNAR1 interferon alpha and beta receptor subunit 1 resistance ISO Cryptococcus (yeast) pneumonia RGD PMID:18566423 PMID:18566423 RGD:5490275, RGD:5490275 NCBI chr21:33,324,395...33,359,864
Ensembl chr21:33,324,387...33,359,864 		JBrowse link
G IFNG interferon gamma EXP CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta treatment ISO
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:31095431 PMID:20080200 RGD:7495767 NCBI chr 8:42,271,302...42,332,460
Ensembl chr 8:42,271,302...42,332,460 		JBrowse link
G IL10 interleukin 10 disease_progression IEP protein:increased expression:blood RGD PMID:20595152 RGD:4140400 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL13 interleukin 13 IEP
EXP		 associated with Respiratory Distress Syndrome, Newborn; protein:increased expression:bronchoalveolar lavage fluid
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:21625544 PMID:19695190 RGD:4145774 NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110 		JBrowse link
G IL13RA2 interleukin 13 receptor subunit alpha 2 IEP mRNA:increased expression:lung, fibroblast RGD PMID:15161635 RGD:4890021 NCBI chr  X:115,003,982...115,017,616
Ensembl chr  X:115,003,975...115,019,977 		JBrowse link
G IL17A interleukin 17A ISO
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:21625544 PMID:20498020 PMID:22848348 RGD:4888524, RGD:9068417 NCBI chr 6:52,186,375...52,190,638
Ensembl chr 6:52,186,375...52,190,638 		JBrowse link
G IL18 interleukin 18 ISO
EXP
IEP		 CTD Direct Evidence: marker/mechanism
associated with reperfusion injury
mRNA, protein:increased expression:lung,bronchoalveolar fluid
protein:increased expression:serum		 CTD
RGD		 PMID:21625544 PMID:17400729 PMID:16052682 PMID:11739527 PMID:15955140 RGD:4889590, RGD:4889825, RGD:729357, RGD:4889836 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096 		JBrowse link
G IL1A interleukin 1 alpha ISO mRNA:increased expression:lung RGD PMID:8806881 RGD:7794765 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493 		JBrowse link
G IL1B interleukin 1 beta IEP
HEP
EXP
ISO		 protein:increased expression:lung
mRNA:increased expression:bronchoalveolar lavage (human)
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:lung
mRNA, protein:increased expression:lung		 CTD
RGD		 PMID:21625544 PMID:19825784 PMID:32407669 PMID:20476872 PMID:19901996 More... RGD:4142831, RGD:30296672, RGD:4142536, RGD:4143211, RGD:4142827, RGD:4142812 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL1R1 interleukin 1 receptor type 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 2:102,070,390...102,179,874
Ensembl chr 2:102,064,544...102,179,874 		JBrowse link
G IL1R2 interleukin 1 receptor type 2 EXP
HEP		 CTD Direct Evidence: marker/mechanism
mRNA:increased expression:bronchoalveolar lavage (human)		 CTD
RGD		 PMID:21625544 PMID:32407669 RGD:30296672 NCBI chr 2:101,991,960...102,028,544
Ensembl chr 2:101,991,960...102,028,544 		JBrowse link
G IL1RN interleukin 1 receptor antagonist no_association
disease_progression		 IAGP
HEP
ISO
IDA		 DNA:polymorphism (human)
mRNA:increased expression:bronchoalveolar lavage (human)
mRNA:increased expression:bronchioalveolar lavage fluid, neutrophil (rat)
mRNA:increased expression:lung
DNA:polymorphism:intron (human)		 RGD PMID:19900796 PMID:32407669 PMID:1385928 PMID:16369129 PMID:17569781 More... RGD:4143204, RGD:30296672, RGD:8551846, RGD:4143213, RGD:4142871, RGD:4142865 NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016 		JBrowse link
G IL27 interleukin 27 ISO RGD PMID:19124731 RGD:5128483 NCBI chr16:28,499,362...28,506,834
Ensembl chr16:28,499,362...28,512,051 		JBrowse link
G IL2RB interleukin 2 receptor subunit beta EXP CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr22:37,125,838...37,175,118
Ensembl chr22:37,118,666...37,175,118 		JBrowse link
G IL32 interleukin 32 IEP mRNA:increased expression:peripheral blood mononuclear cell, blood plasma (human) RGD PMID:32860786 RGD:150340740 NCBI chr16:3,065,403...3,069,530
Ensembl chr16:3,065,297...3,082,192 		JBrowse link
G IL33 interleukin 33 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24453940 NCBI chr 9:6,215,149...6,257,983
Ensembl chr 9:6,215,786...6,257,983 		JBrowse link
G IL4 interleukin 4 EXP
HEP		 CTD Direct Evidence: marker/mechanism
mRNA:increased expression:bronchoalveolar lavage (human)		 CTD
RGD		 PMID:21625544 PMID:32407669 RGD:30296672 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G IL4R interleukin 4 receptor HEP mRNA:decreased expression:bronchoalveolar lavage (human) RGD PMID:32407669 RGD:30296672 NCBI chr16:27,313,756...27,364,778
Ensembl chr16:27,313,668...27,364,778 		JBrowse link
G IL5RA interleukin 5 receptor subunit alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 3:3,066,324...3,110,374
Ensembl chr 3:3,066,324...3,126,613 		JBrowse link
G IL6 interleukin 6 disease_progression IEP
EXP		 protein:increased expression:blood
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:21625544 PMID:20595152 RGD:4140400 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G IL6ST interleukin 6 cytokine family signal transducer EXP CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 5:55,935,095...55,994,963
Ensembl chr 5:55,935,095...55,995,022 		JBrowse link
G IRF5 interferon regulatory factor 5 severity IEP RGD PMID:29847542 RGD:40907064 NCBI chr 7:128,937,032...128,950,038
Ensembl chr 7:128,937,457...128,950,038 		JBrowse link
G ITGA2 integrin subunit alpha 2 treatment ISO RGD PMID:11207307 RGD:8693217 NCBI chr 5:52,989,352...53,094,779
Ensembl chr 5:52,989,340...53,094,779 		JBrowse link
G ITGA4 integrin subunit alpha 4 treatment ISO RGD PMID:8703473 RGD:9698424 NCBI chr 2:181,457,205...181,538,940
Ensembl chr 2:181,457,202...181,538,940 		JBrowse link
G ITGB2 integrin subunit beta 2 ISO
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:21625544 PMID:10030843 RGD:6482228 NCBI chr21:44,885,953...44,928,815
Ensembl chr21:44,885,953...44,931,989 		JBrowse link
G ITGB3 integrin subunit beta 3 disease_progression ISO RGD PMID:12746502 RGD:5100478 NCBI chr17:47,253,827...47,313,743
Ensembl chr17:47,253,827...47,313,743 		JBrowse link
G LCN2 lipocalin 2 exacerbates ISO associated with Escherichia Coli Infections RGD PMID:20633248 RGD:126779583 NCBI chr 9:128,149,453...128,153,453
Ensembl chr 9:128,149,071...128,153,453 		JBrowse link
G LIAS lipoic acid synthetase EXP CTD Direct Evidence: therapeutic CTD PMID:32017981 NCBI chr 4:39,459,056...39,479,506
Ensembl chr 4:39,459,004...39,485,109 		JBrowse link
G MBL2 mannose binding lectin 2 IEP protein:increased secretion:lung (human)
protein:increased expression:Bronchoalveolar lavage:		 RGD PMID:18988662 PMID:15249448 RGD:4889459, RGD:8693755 NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784 		JBrowse link
G MIF macrophage migration inhibitory factor severity IAGP DNA:repeats:promoter RGD PMID:19346297 RGD:4891058 NCBI chr22:23,894,383...23,895,223
Ensembl chr22:23,894,383...23,895,227 		JBrowse link
G MIR150 microRNA 150 EXP CTD Direct Evidence: therapeutic CTD PMID:29205062 NCBI chr19:49,500,785...49,500,868
Ensembl chr19:49,500,785...49,500,868 		JBrowse link
G MIR20A microRNA 20a IEP RGD PMID:29115456 RGD:25823151 NCBI chr13:91,351,065...91,351,135
Ensembl chr13:91,351,065...91,351,135 		JBrowse link
G MMP9 matrix metallopeptidase 9 ISO RGD PMID:18007984 RGD:5130157 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MUC1 mucin 1, cell surface associated IEP protein:increased expression:serum RGD PMID:11802251 RGD:5131281 NCBI chr 1:155,185,824...155,192,915
Ensembl chr 1:155,185,824...155,192,916 		JBrowse link
G MUC2 mucin 2, oligomeric mucus/gel-forming treatment ISO RGD PMID:23590300 RGD:7349359 NCBI chr11:1,074,874...1,110,508
Ensembl chr11:1,074,875...1,110,511 		JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:26882889 NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,552...38,143,024 		JBrowse link
G MYLK myosin light chain kinase EXP CTD Direct Evidence: marker/mechanism CTD PMID:15863634 NCBI chr 3:123,610,049...123,884,332
Ensembl chr 3:123,610,049...123,884,332 		JBrowse link
G NFKBIA NFKB inhibitor alpha susceptibility IAGP associated with combined immunodeficiency;DNA:missense mutation:CDS:c.106T>G (p.S36A) (human) RGD PMID:31683054 RGD:126925985 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NRP1 neuropilin 1 treatment ISO RGD PMID:36373992 RGD:401901166 NCBI chr10:33,177,493...33,334,667
Ensembl chr10:33,177,492...33,336,262 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20561897 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G PF4 platelet factor 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 4:73,980,811...73,982,124
Ensembl chr 4:73,980,811...73,982,027 		JBrowse link
G POMC proopiomelanocortin EXP CTD Direct Evidence: marker/mechanism CTD PMID:6254450 NCBI chr 2:25,160,860...25,168,580
Ensembl chr 2:25,160,853...25,168,903 		JBrowse link
G REG3A regenerating family member 3 alpha ISO RGD PMID:12579542 RGD:9831426 NCBI chr 2:79,157,006...79,159,753
Ensembl chr 2:79,157,003...79,159,753 		JBrowse link
G SERPINE1 serpin family E member 1 disease_progression IEP
IAGP		 Pneumonia, Ventilator-Associated; protein:increased expression:Bronchoalveolar Lavage Fluid
DNA:polymorphism:promoter:		 RGD PMID:20473240 PMID:19387177 RGD:4143511, RGD:4143525 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247 		JBrowse link
G SFTPA1 surfactant protein A1 ISO
IEP		 protein:decreased expression:lung RGD PMID:15967375 PMID:8542113 RGD:4143394, RGD:4143452 NCBI chr10:79,610,939...79,615,455
Ensembl chr10:79,610,939...79,615,455 		JBrowse link
G SFTPB surfactant protein B ISO
IMP		 RGD PMID:12594064 PMID:16024721 PMID:15967375 RGD:4143412, RGD:4143393, RGD:4143394 NCBI chr 2:85,657,307...85,668,741
Ensembl chr 2:85,657,314...85,668,741 		JBrowse link
G SFTPC surfactant protein C ISO RGD PMID:15967375 RGD:4143394 NCBI chr 8:22,157,383...22,164,479
Ensembl chr 8:22,156,913...22,164,479 		JBrowse link
G SFTPD surfactant protein D ISO
IMP
IEP		 associated with Bronchitis;protein:decreased expression:lung RGD PMID:15967375 PMID:17925426 PMID:18266831 RGD:4143394, RGD:4143504, RGD:4143517 NCBI chr10:79,937,740...79,982,383
Ensembl chr10:79,937,467...79,982,614 		JBrowse link
G SIRT1 sirtuin 1 EXP CTD Direct Evidence: therapeutic CTD PMID:24633890 NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390 		JBrowse link
G SLC11A2 solute carrier family 11 member 2 ISO RGD PMID:21278260 RGD:5688709 NCBI chr12:50,952,263...51,028,886
Ensembl chr12:50,979,401...51,028,566 		JBrowse link
G SOD3 superoxide dismutase 3 IDA RGD PMID:16842247 RGD:1581268 NCBI chr 4:24,795,573...24,800,842
Ensembl chr 4:24,789,912...24,800,842 		JBrowse link
G SPP1 secreted phosphoprotein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532 		JBrowse link
G TGFB1 transforming growth factor beta 1 severity IEP
EXP
ISO		 CTD Direct Evidence: marker/mechanism
protein:increased expression:lung		 CTD
RGD		 PMID:21625544 PMID:19181604 PMID:19965809 RGD:4145141, RGD:4145120 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G TLR2 toll like receptor 2 susceptibility ISO RGD PMID:19011150 RGD:4145330 NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,070...153,706,260 		JBrowse link
G TLR4 toll like receptor 4 ISO
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:26882889 PMID:20357263 RGD:4142858 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G TNC tenascin C IEP protein:increased expression:serum, respiratory system fluid/secretion RGD PMID:19721293 RGD:4889573 NCBI chr 9:115,019,575...115,118,157
Ensembl chr 9:115,019,575...115,118,207 		JBrowse link
G TNF tumor necrosis factor EXP CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:21625544 PMID:28917655 PMID:34390737 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A EXP CTD Direct Evidence: marker/mechanism CTD PMID:21625544 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114 		JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B susceptibility IDA
EXP
IAGP		 Idiopathic Pneumonia Syndrome
CTD Direct Evidence: marker/mechanism
associated with Carcinoma, Non-Small-Cell Lung; DNA:snp:cds:p.M196R rs1061622 (human)		 CTD
RGD		 PMID:21625544 PMID:18664626 PMID:20811626 RGD:5131448, RGD:5131286 NCBI chr 1:12,166,991...12,209,220
Ensembl chr 1:12,166,991...12,209,228 		JBrowse link
G TNFSF12 TNF superfamily member 12 HEP mRNA:decreased expression:bronchoalveolar lavage (human) RGD PMID:32407669 RGD:30296672 NCBI chr17:7,549,058...7,557,881
Ensembl chr17:7,548,508...7,557,890 		JBrowse link
G VDR vitamin D receptor susceptibility ISO
IAGP		 DNA:SNP: :rs2239185(human) RGD PMID:17224129 PMID:25367052 RGD:4889851, RGD:11074745 NCBI chr12:47,841,537...47,904,994
Ensembl chr12:47,841,537...47,943,048 		JBrowse link
Pneumonia, Ventilator-Associated term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GC GC vitamin D binding protein IEP protein:increased expression:bronchoalveolar fluid: RGD PMID:21136918 RGD:5509873 NCBI chr 4:71,741,693...71,805,520
Ensembl chr 4:71,741,696...71,804,041 		JBrowse link
pneumonic tularemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IDO1 indoleamine 2,3-dioxygenase 1 ISO RGD PMID:20385761 RGD:39938865 NCBI chr 8:39,913,891...39,928,790
Ensembl chr 8:39,902,275...39,928,790 		JBrowse link
pulmonary aspergilloma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTX3 pentraxin 3 IEP protein:increased expression:bronchoalveolar lavage fluid, plasma (human) RGD PMID:29964232 RGD:38508894 NCBI chr 3:157,436,850...157,443,633
Ensembl chr 3:157,436,850...157,443,633 		JBrowse link
pulmonary tuberculosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 treatment IAGP DNA:SNP: :2677G>A (human) RGD PMID:26067842 RGD:11098541 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G ADA adenosine deaminase IEP protein:increased expression:plasma, respiratory system fluid/secretion
protein:increased activity:blood, pulmonary alveolar duct
protein:increased activity:sputum:		 RGD PMID:12194640 PMID:2212911 PMID:19460251 RGD:5128854, RGD:152995390, RGD:152995271 NCBI chr20:44,619,522...44,651,699
Ensembl chr20:44,584,896...44,652,252 		JBrowse link
G ADA2 adenosine deaminase 2 IEP protein:increased activity:sputum: RGD PMID:19460251 RGD:152995271 NCBI chr22:17,178,790...17,221,848
Ensembl chr22:17,178,790...17,258,235 		JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing IEP protein:increased expression:plasma RGD PMID:22022605 RGD:5686405 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 susceptibility IAGP DNA:SNP,haplotype:intron: IVS3+18 C/C (human) RGD PMID:20141546 RGD:38676498 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751 		JBrowse link
G ALOX5 arachidonate 5-lipoxygenase susceptibility IAGP DNA:polymorphism, repeat:promoter, exon:g.760G>A (human) RGD PMID:18174194 RGD:4890411 NCBI chr10:45,374,216...45,446,117
Ensembl chr10:45,374,176...45,446,119 		JBrowse link
G ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25774636 NCBI chr 8:130,052,104...130,443,674
Ensembl chr 8:130,052,104...130,443,674 		JBrowse link
G ATF3 activating transcription factor 3 IEP mRNA,protein:increased expression:lung RGD PMID:20856677 RGD:34888225 NCBI chr 1:212,565,407...212,620,777
Ensembl chr 1:212,565,334...212,620,777 		JBrowse link
G C3 complement C3 IEP RGD PMID:19472039 RGD:5129500 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562 		JBrowse link
G CCL1 C-C motif chemokine ligand 1 susceptibility ISO
IAGP		 mRNA:increased expression:lung, dendritic cell
DNA:SNP: :multiple (human)		 RGD PMID:18703681 PMID:19057661 RGD:4891409, RGD:4891408 NCBI chr17:34,360,328...34,363,233
Ensembl chr17:34,360,328...34,363,233 		JBrowse link
G CCL19 C-C motif chemokine ligand 19 ISO mRNA:increased expression:lung RGD PMID:19933855 RGD:5130906 NCBI chr 9:34,689,570...34,691,276
Ensembl chr 9:34,689,570...34,691,276 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 susceptibility IAGP
EXP		 DNA:polymorphism: :-2518A>G (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:16352737 PMID:18940815 PMID:20111728 RGD:4891439 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 susceptibility IAGP
IEP		 DNA:snps:5' utr:g.-403G>A rs2280788, g.-28C>G rs2107538 (human)
mRNA:increased expression:lung (human)		 RGD PMID:19335954 PMID:15128813 RGD:4891879, RGD:4892112 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793 		JBrowse link
G CCR2 C-C motif chemokine receptor 2 disease_progression ISO RGD PMID:11438742 RGD:734715 NCBI chr 3:46,354,111...46,360,940
Ensembl chr 3:46,353,864...46,360,940 		JBrowse link
G CCR5 C-C motif chemokine receptor 5 IEP protein:decreased expression:blood, T cell (human) RGD PMID:16379602 RGD:4892094 NCBI chr 3:46,370,142...46,376,206
Ensembl chr 3:46,370,946...46,376,206 		JBrowse link
G CD14 CD14 molecule susceptibility IEP
IAGP		 protein:increased expression:monocyte, serum
DNA:polymorphism:promoter:c. -159C>T (human)		 RGD PMID:18008256 PMID:18008256 RGD:4144205, RGD:4144205 NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,700 		JBrowse link
G CD163 CD163 molecule exacerbates IEP protein:increased expression:blood plasma, CD14-positive monocyte (human)
protein:increased expression:blood serum (human)		 RGD PMID:27685837 PMID:27684274 RGD:127285801, RGD:127345136 NCBI chr12:7,470,811...7,503,777
Ensembl chr12:7,470,811...7,503,893 		JBrowse link
G CD1D CD1d molecule susceptibility IAGP DNA:SNPS, haplotype:intron, enhancer: (rs859009,rs859010, rs973742) (human) RGD PMID:30972222 RGD:127345096 NCBI chr 1:158,178,030...158,186,427
Ensembl chr 1:158,178,030...158,186,427 		JBrowse link
G CD209 CD209 molecule susceptibility EXP
IAGP		 CTD Direct Evidence: marker/mechanism
associated with HIV Seropositivity; DNA:SNP:promoter: -336A>G (rs4804803) (human)
DNA:SNPs:promoter:-139G>A, -336A>G, -871A>G (rs2287886,rs4804803,rs735239) (human)		 CTD
RGD		 PMID:16379498 PMID:19126442 PMID:24874302 RGD:39939062, RGD:39938981 NCBI chr19:7,739,993...7,747,534
Ensembl chr19:7,739,993...7,747,564 		JBrowse link
G CD274 CD274 molecule IEP protein:increased expression:Tcell, B cell, monocyte RGD PMID:23661793 RGD:40818418 NCBI chr 9:5,450,542...5,470,554
Ensembl chr 9:5,450,503...5,470,566 		JBrowse link
G CD36 CD36 molecule (CD36 blood group) susceptibility IAGP DNA:SNPs: :rs1194182, rs10499859(human) RGD PMID:28693442 RGD:41412192 NCBI chr 7:80,602,207...80,679,274
Ensembl chr 7:80,369,575...80,679,277 		JBrowse link
G CD86 CD86 molecule IEP protein:decreased expression:sputum, macrophage (human) RGD PMID:17713660 RGD:4892339 NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139 		JBrowse link
G CLEC4M C-type lectin domain family 4 member M susceptibility ISO
IAGP		 DNA:repeats:exon 4: allele 4, allele 5, allele 9 (human) RGD PMID:19770268 PMID:24874302 PMID:17224292 RGD:39938983, RGD:39938981, RGD:39938987 NCBI chr19:7,763,243...7,769,605
Ensembl chr19:7,763,210...7,769,605 		JBrowse link
G CRP C-reactive protein severity IEP associated with HIV Infections RGD PMID:21219690 PMID:21197091 RGD:5131284, RGD:5131287 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589 		JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 treatment IEP RGD PMID:29843631 RGD:27095956 NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497 		JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 disease_progression ISO RGD PMID:20454613 RGD:5135037 NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196 		JBrowse link
G CXCL5 C-X-C motif chemokine ligand 5 susceptibility ISO mRNA:increased expression:lung RGD PMID:16790804 RGD:5135246 NCBI chr 4:73,995,642...73,998,677
Ensembl chr 4:73,995,642...73,998,677 		JBrowse link
G CXCL6 C-X-C motif chemokine ligand 6 susceptibility ISO mRNA:increased expression:lung RGD PMID:16790804 RGD:5135246 NCBI chr 4:73,836,678...73,838,760
Ensembl chr 4:73,836,640...73,849,064 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 exacerbates IEP
HEP		 protein:increased expression:serum (human)
RNA:increased expression:blood plasma (human)		 RGD PMID:16001981 PMID:27434276 RGD:39939055, RGD:150523784 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CYBA cytochrome b-245 alpha chain no_association IAGP DNA:SNPs:exons:214C>T (rs4673), 521C>T (rs17845095) (human) RGD PMID:16608528 RGD:4780358 NCBI chr16:88,643,289...88,651,053
Ensembl chr16:88,643,275...88,651,083 		JBrowse link
G DDIT3 DNA damage inducible transcript 3 IEP mRNA,protein:increased expression:lung RGD PMID:20856677 RGD:34888225 NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737 		JBrowse link
G EGFR epidermal growth factor receptor disease_progression IAGP associated with lung adenocarcinoma; RGD PMID:29621876 PMID:22173705 RGD:38599162, RGD:38599176 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G EREG epiregulin susceptibility IAGP DNA:SNP:exon 4: (rs2367707) (human) RGD PMID:30634928 RGD:39457687 NCBI chr 4:74,365,145...74,388,749
Ensembl chr 4:74,365,145...74,388,749 		JBrowse link
G FOXP3 forkhead box P3 susceptibility IAGP DNA:polymorphism:promoter:-924A>G(human) RGD PMID:29020928 RGD:38501101 NCBI chr  X:49,250,438...49,264,710
Ensembl chr  X:49,250,438...49,264,800 		JBrowse link
G GBE1 1,4-alpha-glucan branching enzyme 1 IAGP DNA:SNP:intron:rs2307058 (human) RGD PMID:28355295 RGD:18337291 NCBI chr 3:81,489,703...81,761,645
Ensembl chr 3:81,489,703...81,761,645 		JBrowse link
G GSTM1 glutathione S-transferase mu 1 susceptibility IAGP associated with GSTT1 null deletion; DNA:deletion: : RGD PMID:20297661 RGD:4140932 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039 		JBrowse link
G GSTT1 glutathione S-transferase theta 1 susceptibility IAGP DNA:deletion: : RGD PMID:20297661 RGD:4140932
G HAVCR2 hepatitis A virus cellular receptor 2 IEP RGD PMID:21382414 RGD:5135524 NCBI chr 5:157,085,832...157,109,044
Ensembl chr 5:157,085,422...157,142,869 		JBrowse link
G HLA-DPB1 major histocompatibility complex, class II, DP beta 1 IAGP RGD PMID:18652916 RGD:5144001 NCBI chr 6:33,075,990...33,089,696
Ensembl chr 6:33,075,990...33,089,696 		JBrowse link
G HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 disease_progression
susceptibility		 IAGP DNA:polymorphisms (human)
DNA:polymorphism: :HLA-DQB1*3:03(human)
DNA:polymorphism:cds:HLA-DQB1*0201(human)		 RGD PMID:19230186 PMID:28612994 PMID:24024195 RGD:5147614, RGD:36049765, RGD:36049753 NCBI chr 6:32,659,467...32,666,657
Ensembl chr 6:32,659,467...32,668,383 		JBrowse link
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 susceptibility IAGP DNA:polymorphism:cds:HLA-DRB1*0201(human)
DNA:polymorphism: :HLA-DRB1*09:01(human)		 RGD PMID:24024195 PMID:28612994 RGD:36049753, RGD:36049765 NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,577,902...32,589,848 		JBrowse link
G IDO1 indoleamine 2,3-dioxygenase 1 treatment IEP RGD PMID:32369456 RGD:39939073 NCBI chr 8:39,913,891...39,928,790
Ensembl chr 8:39,902,275...39,928,790 		JBrowse link
G IL13 interleukin 13 IEP mRNA:increased expression:Leukocytes, Mononuclear RGD PMID:10608794 RGD:4145649 NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110 		JBrowse link
G IL15 interleukin 15 IEP mRNA, protein:increased expression:lung RGD PMID:11742275 RGD:4990461 NCBI chr 4:141,636,583...141,733,987
Ensembl chr 4:141,636,583...141,733,987 		JBrowse link
G IL18 interleukin 18 IEP protein:increased expression:serum RGD PMID:15955140 RGD:4889836 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096 		JBrowse link
G IL1A interleukin 1 alpha ISO RGD PMID:9176116 RGD:4142835 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493 		JBrowse link
G IL1B interleukin 1 beta severity
susceptibility		 IEP
IAGP		 protein:increased expression:lung
DNA:polymorphism: :3953T>C (human)
protein:increased expression:bronchioalveolar lavage fluid (human)		 RGD PMID:10543265 PMID:16634865 PMID:10631206 RGD:4143180, RGD:5147843, RGD:4143179 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL1RL1 interleukin 1 receptor like 1 ISO RGD PMID:28128217 RGD:39938965 NCBI chr 2:102,311,563...102,352,356
Ensembl chr 2:102,311,502...102,352,037 		JBrowse link
G IL1RN interleukin 1 receptor antagonist severity IEP
IDA		 protein:increased expression:lung, serum RGD PMID:10543265 PMID:14619382 PMID:10631206 RGD:4143180, RGD:4143174, RGD:4143179 NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016 		JBrowse link
G IL23A interleukin 23 subunit alpha ISO mRNA:increased expression:lung (mouse) RGD PMID:16002675 PMID:21156751 PMID:20624887 PMID:11801672 RGD:39457949, RGD:39458038, RGD:39458036, RGD:39457953 NCBI chr12:56,338,884...56,340,410
Ensembl chr12:56,334,174...56,340,410 		JBrowse link
G IL27 interleukin 27 exacerbates IAGP DNA:SNPs:promoter, exon:-964A>G, 2905T>G (human)
DNA:SNPs:promoter,exons:-964A>G, 2905T>G, 4730T>C (rs153109, rs17855750, rs181206) (human)		 RGD PMID:31949807 PMID:30948177 RGD:126790508, RGD:39456132 NCBI chr16:28,499,362...28,506,834
Ensembl chr16:28,499,362...28,512,051 		JBrowse link
G IL27RA interleukin 27 receptor subunit alpha ISO RGD PMID:15749890 RGD:5128486 NCBI chr19:14,031,762...14,053,218
Ensembl chr19:14,031,762...14,053,218 		JBrowse link
G IL32 interleukin 32 treatment IEP RGD PMID:31378983 RGD:150340743 NCBI chr16:3,065,403...3,069,530
Ensembl chr16:3,065,297...3,082,192 		JBrowse link
G IL33 interleukin 33 ISO RGD PMID:28128217 RGD:39938965 NCBI chr 9:6,215,149...6,257,983
Ensembl chr 9:6,215,786...6,257,983 		JBrowse link
G IL4 interleukin 4 severity ISO RGD PMID:20832364 RGD:5128550 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G IL4R interleukin 4 receptor IEP protein:decreased expression:serum RGD PMID:21251883 RGD:5128510 NCBI chr16:27,313,756...27,364,778
Ensembl chr16:27,313,668...27,364,778 		JBrowse link
G IL6 interleukin 6 IEP RGD PMID:20624776 RGD:4143257 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G IL6R interleukin 6 receptor IEP protein:decreased expression:T cell RGD PMID:20019339 RGD:5128632 NCBI chr 1:154,405,343...154,469,450
Ensembl chr 1:154,405,193...154,469,450 		JBrowse link
G IRF1 interferon regulatory factor 1 ISO RGD PMID:11083808 RGD:5128719 NCBI chr 5:132,481,609...132,490,773
Ensembl chr 5:132,440,440...132,508,719 		JBrowse link
G ITIH4 inter-alpha-trypsin inhibitor heavy chain 4 IEP protein:increased expression:urine RGD PMID:29636444 RGD:40903003 NCBI chr 3:52,812,962...52,830,672
Ensembl chr 3:52,812,962...52,830,688 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit IDA protein:decreased phosphorylation:macrophage, nucleus RGD PMID:19737230 RGD:4889999 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048 		JBrowse link
G KIR3DS1 killer cell immunoglobulin like receptor, three Ig domains and short cytoplasmic tail 1 susceptibility IAGP DNA:deletion: RGD PMID:22653583 RGD:150340566
G LCN2 lipocalin 2 exacerbates
disease_progression		 ISO RGD PMID:19050270 PMID:30534124 RGD:126779558, RGD:126779565 NCBI chr 9:128,149,453...128,153,453
Ensembl chr 9:128,149,071...128,153,453 		JBrowse link
G LTA lymphotoxin alpha susceptibility IAGP DNA:polymorphism:intron:252G>A (human) RGD PMID:20180006 RGD:4143234 NCBI chr 6:31,560,610...31,574,324
Ensembl chr 6:31,572,054...31,574,324 		JBrowse link
G MARCO macrophage receptor with collagenous structure susceptibility IAGP DNA:SNP: :rs12998782(human)
DNA:SNPs:introns:rs4491733,rs12998782,rs13389814,rs7559955 (human)
DNA:SNPs: :rs2278589, rs6751745,rs6748401 (human)		 RGD PMID:28693442 PMID:23617307 PMID:27853145 RGD:41412192, RGD:41412195, RGD:41412194 NCBI chr 2:118,942,194...118,994,660
Ensembl chr 2:118,942,194...118,994,660 		JBrowse link
G MBL2 mannose binding lectin 2 IAGP DNA:polymorphisms:5' utr, exon:multiple (human) RGD PMID:19199550 RGD:4889452 NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784 		JBrowse link
G MIF macrophage migration inhibitory factor susceptibility IAGP DNA:SNP: :rs755622 (human) RGD PMID:20439102 RGD:4891004 NCBI chr22:23,894,383...23,895,223
Ensembl chr22:23,894,383...23,895,227 		JBrowse link
G MIR30A microRNA 30a disease_progression IEP RGD PMID:25866116 RGD:35668864 NCBI chr 6:71,403,551...71,403,621
Ensembl chr 6:71,403,551...71,403,621 		JBrowse link
G MMP3 matrix metallopeptidase 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24890593 NCBI chr11:102,835,801...102,843,609
Ensembl chr11:102,835,801...102,843,609 		JBrowse link
G MMP7 matrix metallopeptidase 7 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24890593 NCBI chr11:102,520,508...102,530,747
Ensembl chr11:102,520,508...102,530,750 		JBrowse link
G MMP8 matrix metallopeptidase 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24890593 NCBI chr11:102,711,796...102,724,954
Ensembl chr11:102,711,796...102,727,050 		JBrowse link
G MMP9 matrix metallopeptidase 9 ISO RGD PMID:16982845 RGD:5130746 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G NAT2 N-acetyltransferase 2 susceptibility IAGP RGD PMID:20297661 RGD:4140932 NCBI chr 8:18,386,301...18,401,218
Ensembl chr 8:18,391,282...18,401,218 		JBrowse link
G NFKBIA NFKB inhibitor alpha IEP mRNA:increased expression:peripheral blood mononuclear cell (human) RGD PMID:9379002 RGD:126908014 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 susceptibility IAGP DNA:SNPs:CDs:p.P268S, R702W, A725G (human) RGD PMID:18419343 RGD:5131510 NCBI chr16:50,693,606...50,733,075
Ensembl chr16:50,693,588...50,733,077 		JBrowse link
G NOS2 nitric oxide synthase 2 IAGP DNA:SNPs:multiple (human) RGD PMID:19575238 RGD:4144122 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G PDCD1 programmed cell death 1 treatment IEP protein:increased expression:Tcell, B cell, monocyte RGD PMID:23661793 PMID:23661793 RGD:40818418, RGD:40818418 NCBI chr 2:241,849,884...241,858,894
Ensembl chr 2:241,849,884...241,858,894 		JBrowse link
G PDCD1LG2 programmed cell death 1 ligand 2 IEP protein:increased expression:Tcell, B cell, monocyte RGD PMID:23661793 RGD:40818418 NCBI chr 9:5,510,531...5,571,282
Ensembl chr 9:5,510,531...5,571,282 		JBrowse link
G PLAUR plasminogen activator, urokinase receptor severity IEP RGD PMID:18359089 RGD:6483832 NCBI chr19:43,646,095...43,670,169
Ensembl chr19:43,646,095...43,670,547 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 IAGP DNA:SNPs:cds:788G>A, 1858C>T (human) RGD PMID:19563523 RGD:6484723 NCBI chr 1:113,813,811...113,871,759
Ensembl chr 1:113,813,811...113,871,753 		JBrowse link
G SFTPA1 surfactant protein A1 susceptibility IAGP DNA:SNP:intron:1416C>T (human)
DNA:SNPs:exons:307G>A, 776C>T (human)		 RGD PMID:12476938 PMID:16292672 RGD:4144875, RGD:4144874 NCBI chr10:79,610,939...79,615,455
Ensembl chr10:79,610,939...79,615,455 		JBrowse link
G SLC11A1 solute carrier family 11 member 1 susceptibility IAGP DNA:polymorphism:intron (human)
DNA:deletion:3'UTR:		 RGD PMID:21169917 PMID:24024195 RGD:5684974, RGD:36049753 NCBI chr 2:218,382,273...218,396,894
Ensembl chr 2:218,382,029...218,396,894 		JBrowse link
G TAP1 transporter 1, ATP binding cassette subfamily B member IAGP associated with HIV Infections; RGD PMID:21843574 RGD:6482248 NCBI chr 6:32,845,209...32,853,704
Ensembl chr 6:32,845,209...32,853,816 		JBrowse link
G TAP2 transporter 2, ATP binding cassette subfamily B member susceptibility IAGP DNA:polymorphism: : RGD PMID:9062973 RGD:5147851 NCBI chr 6:32,821,831...32,838,739
Ensembl chr 6:32,821,833...32,838,739 		JBrowse link
G TLR1 toll like receptor 1 IEP mRNA:increased expression:blood RGD PMID:16493059 RGD:4889525 NCBI chr 4:38,787,569...38,805,644
Ensembl chr 4:38,790,677...38,856,817 		JBrowse link
G TLR2 toll like receptor 2 susceptibility IEP
IAGP		 mRNA, protein:increased expression:blood, T cell
DNA:SNP: :rs1816702 (human)
DNA:polymorphism:intron (human)
DNA:polymorphisms: :multiple (human)		 RGD PMID:19552525 PMID:19723394 PMID:20298136 PMID:20113509 RGD:4145355, RGD:4145323, RGD:4145304, RGD:4145320 NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,070...153,706,260 		JBrowse link
G TLR4 toll like receptor 4 susceptibility
severity		 IEP
IAGP		 protein:increased expression:monocyte
DNA:SNP:intron: rs5030729 (human)
DNA:polymorphisms:cds: p. D299F, T399I (human)		 RGD PMID:18008256 PMID:19575238 PMID:20403143 RGD:4144205, RGD:4144122, RGD:4144106 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G TLR9 toll like receptor 9 IAGP DNA:snps:multiple (human) RGD PMID:19771452 RGD:5130704 NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,225,645 		JBrowse link
G TNF tumor necrosis factor disease_progression
susceptibility		 IDA
ISO
IAGP		 DNA:polymorphisms::c.-857 C>T, c. -863 A>C (human) RGD PMID:18212516 PMID:9176116 PMID:20650298 RGD:4143395, RGD:4142835, RGD:4143388 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TREM1 triggering receptor expressed on myeloid cells 1 disease_progression IEP RGD PMID:29844416 RGD:126925977 NCBI chr 6:41,267,385...41,286,682
Ensembl chr 6:41,267,926...41,286,682 		JBrowse link
G VDR vitamin D receptor susceptibility IAGP DNA:SNPs:5' UTR (human)
DNA:SNP (human)
DNA:SNPs:promoter, 3' UTR (human)
DNA:SNPs (human)		 RGD PMID:18397302 PMID:20231985 PMID:17236578 PMID:18231846 PMID:15295697 RGD:4889842, RGD:4889830, RGD:4889849, RGD:4889845, RGD:4889853 NCBI chr12:47,841,537...47,904,994
Ensembl chr12:47,841,537...47,943,048 		JBrowse link
Recurrent Respiratory Papillomatosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD274 CD274 molecule IEP protein:increased expression: larynx RGD PMID:22322668 RGD:40822813 NCBI chr 9:5,450,542...5,470,554
Ensembl chr 9:5,450,503...5,470,566 		JBrowse link
G FOXP3 forkhead box P3 susceptibility IAGP DNA:SNPs:promoter:rs5902434,rs2232365 (human) RGD PMID:28298239 RGD:38549360 NCBI chr  X:49,250,438...49,264,710
Ensembl chr  X:49,250,438...49,264,800 		JBrowse link
G HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 severity IAGP DNA:polymorphisms:cds:HLA-DQB1*0201, HLA-DQB1*0602 (human)
DNA:polymorphism: :HLA-DQB1*0602(human)		 RGD PMID:15336778 PMID:19861144 RGD:5147657, RGD:36174013 NCBI chr 6:32,659,467...32,666,657
Ensembl chr 6:32,659,467...32,668,383 		JBrowse link
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 severity IAGP DNA:polymorphisms:cds:HLA-DRB1*0301, HLA-DRB1*0102 (human) RGD PMID:15336778 RGD:5147657 NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,577,902...32,589,848 		JBrowse link
G IL32 interleukin 32 IEP mRNA:decreased expression:blood serum (human) RGD PMID:24015634 RGD:150340746 NCBI chr16:3,065,403...3,069,530
Ensembl chr16:3,065,297...3,082,192 		JBrowse link
G KIR2DS1 killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 1 severity IAGP RGD PMID:19861144 RGD:36174013
G KIR2DS5 killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 5 severity IAGP RGD PMID:19861144 RGD:36174013
G KIR3DS1 killer cell immunoglobulin like receptor, three Ig domains and short cytoplasmic tail 1 severity IAGP RGD PMID:19861144 RGD:36174013
G NLRP1 NLR family pyrin domain containing 1 IAGP ClinVar Annotator: match by term: Respiratory papillomatosis, juvenile recurrent, congenital ClinVar
OMIM		 PMID:17377159 PMID:24033266 PMID:25741868 PMID:28492532 PMID:31484767 NCBI chr17:5,501,396...5,584,509
Ensembl chr17:5,499,415...5,619,424 		JBrowse link
G PDCD1 programmed cell death 1 IEP RGD PMID:22322668 RGD:40822813 NCBI chr 2:241,849,884...241,858,894
Ensembl chr 2:241,849,884...241,858,894 		JBrowse link
G TAP1 transporter 1, ATP binding cassette subfamily B member severity IAGP DNA:polymorphism:cds:p.D637G(human) RGD PMID:14976605 RGD:5147844 NCBI chr 6:32,845,209...32,853,704
Ensembl chr 6:32,845,209...32,853,816 		JBrowse link
RESPIRATORY INFECTIONS, RECURRENT, AND FAILURE TO THRIVE WITH OR WITHOUT DIARRHEA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGR2 anterior gradient 2, protein disulphide isomerase family member IAGP ClinVar Annotator: match by term: Respiratory infections, recurrent, and failure to thrive with or without diarrhea OMIM
ClinVar		 PMID:25741868 PMID:34952832 NCBI chr 7:16,791,811...16,804,999
Ensembl chr 7:16,791,811...16,833,433 		JBrowse link
rhinitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM33 ADAM metallopeptidase domain 33 susceptibility IAGP DNA:SNPs: :multiple (human) RGD PMID:18778489 PMID:15298558 RGD:4145378, RGD:4145383 NCBI chr20:3,667,975...3,682,010
Ensembl chr20:3,667,965...3,682,246 		JBrowse link
G ANG angiogenin IEP protein:increased expression:sputum RGD PMID:19178538 RGD:6892723 NCBI chr14:20,684,177...20,694,186
Ensembl chr14:20,684,177...20,698,971 		JBrowse link
G BDKRB1 bradykinin receptor B1 IEP RGD PMID:12165532 RGD:5129220 NCBI chr14:96,256,210...96,264,763
Ensembl chr14:96,256,210...96,268,967 		JBrowse link
G BDKRB2 bradykinin receptor B2 IDA
IMP		 RGD PMID:1890650 PMID:11149999 RGD:4891044, RGD:4891033 NCBI chr14:96,204,839...96,244,164
Ensembl chr14:96,204,679...96,244,166 		JBrowse link
G BDNF brain derived neurotrophic factor susceptibility ISO
IAGP		 mRNA:increased expression:nasal cavity epithelium
DNA:SNP,haplotypes: :rs10767664,rs12273539,rs962369(human)		 RGD PMID:20464992 PMID:21723144 RGD:4891116, RGD:8655967 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058 		JBrowse link
G C3 complement C3 ISO
IEP		 mRNA:increased expression:nasal cavity epithelium RGD PMID:17345707 PMID:20109314 RGD:5129524, RGD:5129539 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562 		JBrowse link
G C3AR1 complement C3a receptor 1 severity IEP protein:increased expression:nasal cavity RGD PMID:18538384 RGD:5129559 NCBI chr12:8,056,844...8,066,359
Ensembl chr12:8,056,844...8,066,359 		JBrowse link
G C5AR1 complement C5a receptor 1 IEP RGD PMID:18538384 RGD:5129559 NCBI chr19:47,307,477...47,322,066
Ensembl chr19:47,290,023...47,322,066 		JBrowse link
G CASP1 caspase 1 IEP
ISO		 protein:increased expression:serum RGD PMID:12396474 PMID:20974310 RGD:5130192, RGD:5130187 NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250 		JBrowse link
G CAT catalase treatment ISO protein:increased activity:blood,nasal cavity mucosa: RGD PMID:21541033 RGD:9479054 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CCL1 C-C motif chemokine ligand 1 IEP mRNA:increased expression:nasal cavity epithelium RGD PMID:17982926 RGD:4145109 NCBI chr17:34,360,328...34,363,233
Ensembl chr17:34,360,328...34,363,233 		JBrowse link
G CCL11 C-C motif chemokine ligand 11 severity IEP
ISO		 associated with Sinusitis;protein:increased expression:paranasal sinus
protein:increased expression:nasal mucus
mRNA:increased expression:lung, nose		 RGD PMID:17999785 PMID:16120080 PMID:16765544 RGD:4145455, RGD:4145411, RGD:4145462 NCBI chr17:34,285,742...34,288,334
Ensembl chr17:34,285,742...34,288,334 		JBrowse link
G CCL17 C-C motif chemokine ligand 17 IEP protein:increased expression:blood, mononuclear cell RGD PMID:17517104 RGD:4145498 NCBI chr16:57,396,093...57,416,063
Ensembl chr16:57,404,767...57,416,063 		JBrowse link
G CCL19 C-C motif chemokine ligand 19 ISO RGD PMID:17947663 RGD:5130909 NCBI chr 9:34,689,570...34,691,276
Ensembl chr 9:34,689,570...34,691,276 		JBrowse link
G CCL22 C-C motif chemokine ligand 22 IEP protein:increased expression:blood, mononuclear cell RGD PMID:17517104 RGD:4145498 NCBI chr16:57,357,909...57,366,189
Ensembl chr16:57,358,783...57,366,189 		JBrowse link
G CCL24 C-C motif chemokine ligand 24 IEP
IAGP		 mRNA:increased expression:nasal cavity epithelium
DNA:SNPs: :179T>C, 275C>T (human)		 RGD PMID:17982926 PMID:15580493 RGD:4145109, RGD:4891493 NCBI chr 7:75,810,825...75,823,372
Ensembl chr 7:75,810,825...75,823,356 		JBrowse link
G CCL26 C-C motif chemokine ligand 26 IAGP
IEP		 DNA:polymorphism: :2497T>G (human)
associated with Eosinophilia;protein:increased expression:oronasal secretion (human)		 RGD PMID:15580493 PMID:24989688 RGD:4891493, RGD:11531119 NCBI chr 7:75,769,524...75,791,597
Ensembl chr 7:75,769,533...75,789,896 		JBrowse link
G CCL4 C-C motif chemokine ligand 4 IEP RGD PMID:19786211 RGD:5130914 NCBI chr17:36,103,827...36,105,614
Ensembl chr17:36,103,827...36,105,621 		JBrowse link
G CCL7 C-C motif chemokine ligand 7 IEP RGD PMID:17982926 RGD:4145109 NCBI chr17:34,270,221...34,272,242
Ensembl chr17:34,270,221...34,272,242 		JBrowse link
G CCL8 C-C motif chemokine ligand 8 IEP RGD PMID:20625511 RGD:5131089 NCBI chr17:34,319,435...34,321,402
Ensembl chr17:34,319,435...34,321,402 		JBrowse link
G CCR2 C-C motif chemokine receptor 2 susceptibility IAGP Rhinitis, Allergic, Seasonal; DNA:SNP:cds:p.V64I (human) RGD PMID:17135764 RGD:4145111 NCBI chr 3:46,354,111...46,360,940
Ensembl chr 3:46,353,864...46,360,940 		JBrowse link
G CCR3 C-C motif chemokine receptor 3 ISO
IEP
IAGP		 mRNA:increased expression:nose
protein:increased expression:blood, T cell
DNA:SNP:exon:51T>C (human)		 RGD PMID:20696593 PMID:17156343 PMID:17135764 RGD:4145454, RGD:4145645, RGD:4145111 NCBI chr 3:46,210,696...46,266,706
Ensembl chr 3:46,130,890...46,266,706 		JBrowse link
G CD14 CD14 molecule susceptibility
resistance		 IAGP DNA:polymorphism:promoter:c. -159c>T (human) RGD PMID:20109306 PMID:16950285 RGD:4144795, RGD:4144810 NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,700 		JBrowse link
G CD28 CD28 molecule IEP RGD PMID:21356099 RGD:5131612 NCBI chr 2:203,706,482...203,738,912
Ensembl chr 2:203,706,475...203,738,912 		JBrowse link
G CD80 CD80 molecule ISO RGD PMID:21108691 RGD:5132622 NCBI chr 3:119,524,293...119,559,614
Ensembl chr 3:119,524,293...119,559,614 		JBrowse link
G CDC42 cell division cycle 42 IEP mRNA:increased expression:nasal turbinate RGD PMID:19432938 RGD:5688273 NCBI chr 1:22,052,709...22,101,360
Ensembl chr 1:22,052,627...22,101,360 		JBrowse link
G CFTR CF transmembrane conductance regulator EXP CTD Direct Evidence: marker/mechanism CTD PMID:16083808 NCBI chr 7:117,480,025...117,668,665
Ensembl chr 7:117,287,120...117,715,971 		JBrowse link
G CRHR1 corticotropin releasing hormone receptor 1 IEP mRNA, protein:increased expression:nasal cavity epithelium RGD PMID:17597629 RGD:5130940 NCBI chr17:45,784,320...45,835,828
Ensembl chr17:45,784,277...45,835,828 		JBrowse link
G CRHR2 corticotropin releasing hormone receptor 2 IEP mRNA, protein:increased expression:nasal cavity epithelium RGD PMID:17597629 RGD:5130940 NCBI chr 7:30,651,942...30,700,103
Ensembl chr 7:30,651,942...30,700,129 		JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 IEP protein:increased expression:T cell RGD PMID:17625281 RGD:4891512 NCBI chr 2:203,867,771...203,873,965
Ensembl chr 2:203,853,888...203,873,965 		JBrowse link
G CX3CL1 C-X3-C motif chemokine ligand 1 IEP protein:increased expression:plasma RGD PMID:14657873 RGD:4891906 NCBI chr16:57,372,490...57,385,044
Ensembl chr16:57,372,477...57,385,044 		JBrowse link
G CXCL6 C-X-C motif chemokine ligand 6 IEP protein:increased expression:nasal mucus RGD PMID:20659080 RGD:4892030 NCBI chr 4:73,836,678...73,838,760
Ensembl chr 4:73,836,640...73,849,064 		JBrowse link
G CYP2D6 cytochrome P450 family 2 subfamily D member 6 IAGP DNA:SNP:3' utr:*1934G>A (human) RGD PMID:20088379 RGD:5143945 NCBI chr22:42,126,499...42,130,810
Ensembl chr22:42,126,499...42,130,865 		JBrowse link
G CYSLTR1 cysteinyl leukotriene receptor 1 IMP
ISO
IEP		 associated with Sinusitis;mRNA:increased expression:nasal cavity epithelium RGD PMID:18946234 PMID:15379985 PMID:17627772 PMID:16689996 RGD:4888516, RGD:4847512, RGD:4781451, RGD:4783198 NCBI chr  X:78,271,468...78,327,611
Ensembl chr  X:78,271,468...78,327,691 		JBrowse link
G CYSLTR2 cysteinyl leukotriene receptor 2 IEP associated with Sinusitis;mRNA:increased expression:nasal cavity epithelium RGD PMID:16689996 RGD:4783198 NCBI chr13:48,653,929...48,711,226
Ensembl chr13:48,653,711...48,711,226 		JBrowse link
G FCER1A Fc epsilon receptor Ia IEP RGD PMID:20650300 RGD:5128714 NCBI chr 1:159,283,575...159,308,202
Ensembl chr 1:159,289,714...159,308,224 		JBrowse link
G FIS1 fission, mitochondrial 1 ISO mRNA, protein:increased expression:nasal cavity mucosa (rat) RGD PMID:28146064 RGD:13204839 NCBI chr 7:101,239,472...101,245,081
Ensembl chr 7:101,239,458...101,252,316 		JBrowse link
G HDC histidine decarboxylase IAGP
ISO		 DNA:SNP: :p.E644D (rs2073440) (human) RGD PMID:20608921 PMID:15054596 RGD:5128884, RGD:5143921 NCBI chr15:50,241,947...50,265,726
Ensembl chr15:50,241,947...50,265,965 		JBrowse link
G HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 susceptibility IAGP DNA:polymorphisms:cds:HLA-DQA1*0201, HLA-DQA1*0302 (human) RGD PMID:14990915 RGD:5147798 NCBI chr 6:32,637,406...32,655,272
Ensembl chr 6:32,628,179...32,647,062 		JBrowse link
G HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 susceptibility IAGP DNA:polymorphism:cds:HLA-DQB1*0602 (human) RGD PMID:14990915 RGD:5147798 NCBI chr 6:32,659,467...32,666,657
Ensembl chr 6:32,659,467...32,668,383 		JBrowse link
G HNMT histamine N-methyltransferase no_association IAGP
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:17651147 PMID:17651147 RGD:5128885 NCBI chr 2:137,964,473...138,016,364
Ensembl chr 2:137,964,020...138,016,364 		JBrowse link
G HRH1 histamine receptor H1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:12167471 NCBI chr 3:11,137,238...11,263,557
Ensembl chr 3:11,137,093...11,263,557 		JBrowse link
G IL13 interleukin 13 disease_progression
susceptibility		 ISO
IAGP		 mRNA:increased expression:nose
associated with asthma; DNA:polymorphisms:promoter:c. -1510A>C, -1055C>T (human)
DNA:polymorphism: :rs1800925 (human)		 RGD PMID:16120094 PMID:20696593 PMID:17088137 PMID:20358028 PMID:20484924 RGD:4206706, RGD:4145454, RGD:4159171, RGD:4145767, RGD:4145534 NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110 		JBrowse link
G IL13RA2 interleukin 13 receptor subunit alpha 2 ISO RGD PMID:17088137 RGD:4159171 NCBI chr  X:115,003,982...115,017,616
Ensembl chr  X:115,003,975...115,019,977 		JBrowse link
G IL15 interleukin 15 ISO RGD PMID:16750998 RGD:5000756 NCBI chr 4:141,636,583...141,733,987
Ensembl chr 4:141,636,583...141,733,987 		JBrowse link
G IL16 interleukin 16 IEP
ISO		 protein:increased expression:serum
protein:increased expression:nasal cavity epithelium, serum		 RGD PMID:18254318 PMID:19295235 RGD:5024932, RGD:5024931 NCBI chr15:81,182,712...81,314,058
Ensembl chr15:81,159,575...81,314,058 		JBrowse link
G IL17A interleukin 17A IEP
IDA		 protein:increased expression:nasal mucosa RGD PMID:20506642 PMID:19927541 RGD:4889137, RGD:4889144 NCBI chr 6:52,186,375...52,190,638
Ensembl chr 6:52,186,375...52,190,638 		JBrowse link
G IL18 interleukin 18 disease_progression ISO
IEP		 protein:increased expression:nasal lavage fluid, bronchoalveolar lavage fluid
rhinitis allergic, seasonal; protein:increased expression:plasma
protein:increased expression:serum		 RGD PMID:17305282 PMID:15934281 PMID:17323858 RGD:4889917, RGD:4889927, RGD:4889916 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096 		JBrowse link
G IL1B interleukin 1 beta susceptibility ISO
IAGP
IEP		 mRNA:increased expression:nasal cavity epithelium
associated with Hypersensitivity;DNA:polymorphism: :-511C>T (human)
associated with Hypersensitivity;protein:increased expression:nasal mucus 		RGD PMID:20490816 PMID:14533660 PMID:10224452 RGD:4142821, RGD:4142859, RGD:4143227 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL1RL1 interleukin 1 receptor like 1 severity IEP associated with Sinusitis;DNA:SNPs: :multiple (human) RGD PMID:19671251 RGD:5144228 NCBI chr 2:102,311,563...102,352,356
Ensembl chr 2:102,311,502...102,352,037 		JBrowse link
G IL1RN interleukin 1 receptor antagonist susceptibility IEP
IAGP		 associated with Hypersensitivity;DNA:repeat:intron (human) RGD PMID:15178892 PMID:14533660 PMID:10224452 RGD:4143215, RGD:4142859, RGD:4143227 NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016 		JBrowse link
G IL2 interleukin 2 susceptibility IAGP DNA:SNP:promoter:rs2069762(human) RGD PMID:16333313 RGD:8663473 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725 		JBrowse link
G IL21 interleukin 21 ISO RGD PMID:17982108 RGD:5147397 NCBI chr 4:122,610,108...122,621,066
Ensembl chr 4:122,610,108...122,621,066 		JBrowse link
G IL22 interleukin 22 severity IEP mRNA:increased expression:blood, mononuclear cell RGD PMID:21535180 RGD:5147409 NCBI chr12:68,248,242...68,253,604
Ensembl chr12:68,248,242...68,253,604 		JBrowse link
G IL23R interleukin 23 receptor susceptibility IAGP DNA:SNP,haplotype: :rs7517847(human) RGD PMID:23696856 RGD:8549605 NCBI chr 1:67,138,637...67,265,903
Ensembl chr 1:67,138,907...67,259,979 		JBrowse link
G IL27RA interleukin 27 receptor subunit alpha ISO RGD PMID:19354069 RGD:5128480 NCBI chr19:14,031,762...14,053,218
Ensembl chr19:14,031,762...14,053,218 		JBrowse link
G IL4 interleukin 4 ISO
EXP		 mRNA:increased expression:nasal cavity epithelium
CTD Direct Evidence: marker/mechanism
protein:increased expression:serum		 CTD
RGD		 PMID:19672097 PMID:21208219 PMID:18826099 RGD:5128558, RGD:2317285 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G IL4R interleukin 4 receptor IAGP DNA:polymorphism: :c.1432T>C (human) RGD PMID:15564773 RGD:4890394 NCBI chr16:27,313,756...27,364,778
Ensembl chr16:27,313,668...27,364,778 		JBrowse link
G IL5 interleukin 5 ISO RGD PMID:11884474 RGD:5128622 NCBI chr 5:132,541,445...132,556,815
Ensembl chr 5:132,541,445...132,556,838 		JBrowse link
G IL9 interleukin 9 IEP RGD PMID:20525149 RGD:5128687 NCBI chr 5:135,892,246...135,895,841
Ensembl chr 5:135,892,246...135,895,841 		JBrowse link
G LEP leptin IDA RGD PMID:19860581 RGD:5128850 NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629 		JBrowse link
G MBL2 mannose binding lectin 2 susceptibility IAGP DNA:polymorphism: : RGD PMID:18831943 RGD:8693717 NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784 		JBrowse link
G MFN1 mitofusin 1 ISO mRNA, protein:increased expression:nasal cavity mucosa (rat) RGD PMID:28146064 RGD:13204839 NCBI chr 3:179,347,709...179,394,936
Ensembl chr 3:179,347,709...179,394,936 		JBrowse link
G MIF macrophage migration inhibitory factor severity IEP
ISO		 protein:increased expression:serum, nasal mucosa RGD PMID:15053202 PMID:15922619 RGD:4891045, RGD:4891056 NCBI chr22:23,894,383...23,895,223
Ensembl chr22:23,894,383...23,895,227 		JBrowse link
G MS4A2 membrane spanning 4-domains A2 IDA RGD PMID:15480314 RGD:5131152 NCBI chr11:60,088,259...60,098,467
Ensembl chr11:60,088,261...60,098,467 		JBrowse link
G MUC5AC mucin 5AC, oligomeric mucus/gel-forming ISO
IEP		 mRNA:increased expression:nose RGD PMID:20696593 PMID:15715404 RGD:4145454, RGD:7364740 NCBI chr11:1,157,953...1,201,138
Ensembl chr11:1,157,953...1,201,138 		JBrowse link
G NGF nerve growth factor IEP associated with Sinusitis;protein:increased expression:respiratory system mucosa
protein:increased expression:respiratory system fluid/secretion		 RGD PMID:19958603 PMID:10224365 RGD:4891064, RGD:4891115 NCBI chr 1:115,285,917...115,338,249
Ensembl chr 1:115,285,904...115,338,770 		JBrowse link
G NGFR nerve growth factor receptor IEP protein:increased expression:blood, eosinophil RGD PMID:18647313 RGD:5144116 NCBI chr17:49,495,293...49,515,008
Ensembl chr17:49,495,293...49,515,008 		JBrowse link
G NOD1 nucleotide binding oligomerization domain containing 1 IEP mRNA:decreased expression:nose RGD PMID:20384614 RGD:5131446 NCBI chr 7:30,424,527...30,478,784
Ensembl chr 7:30,424,527...30,478,784 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 susceptibility IAGP DNA:polymorphisms:cds:2104C>T,2722G>C (human) RGD PMID:12704363 RGD:5131484 NCBI chr16:50,693,606...50,733,075
Ensembl chr16:50,693,588...50,733,077 		JBrowse link
G NOS2 nitric oxide synthase 2 IEP protein:increased expression:nasal mucosa RGD PMID:18254476 RGD:4891910 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NPY neuropeptide Y EXP CTD Direct Evidence: marker/mechanism CTD PMID:12746121 NCBI chr 7:24,284,190...24,291,862
Ensembl chr 7:24,284,188...24,291,862 		JBrowse link
G NTRK1 neurotrophic receptor tyrosine kinase 1 IEP protein:increased expression:eosinophil RGD PMID:18647313 RGD:5144116 NCBI chr 1:156,815,750...156,881,850
Ensembl chr 1:156,815,636...156,881,850 		JBrowse link
G OPA1 OPA1 mitochondrial dynamin like GTPase ISO mRNA, protein:increased expression:nasal cavity mucosa (rat) RGD PMID:28146064 RGD:13204839 NCBI chr 3:193,593,208...193,697,811
Ensembl chr 3:193,593,144...193,697,811 		JBrowse link
G PLAU plasminogen activator, urokinase ISO mRNA:increased expression:nasal cavity epithelium RGD PMID:21339035 RGD:8547809 NCBI chr10:73,909,164...73,917,494
Ensembl chr10:73,909,177...73,917,496 		JBrowse link
G PTGDR2 prostaglandin D2 receptor 2 IEP
ISO		 RGD PMID:19230460 PMID:19608418 RGD:5135021, RGD:5135017 NCBI chr11:60,850,933...60,855,950
Ensembl chr11:60,850,933...60,855,950 		JBrowse link
G SCGB3A2 secretoglobin family 3A member 2 IEP protein:increased expression:sputum
mRNA,protein:decreased expression:nasal mucosa		 RGD PMID:17218572 PMID:21385388 RGD:5144232, RGD:5147389 NCBI chr 5:147,878,711...147,882,191
Ensembl chr 5:147,870,682...147,882,191 		JBrowse link
G SERPINE1 serpin family E member 1 susceptibility IAGP DNA:polymorphism:promoter:rs1799768 (human) RGD PMID:19063817 RGD:4144832 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247 		JBrowse link
G SFTPD surfactant protein D susceptibility IAGP associated with Hypersensitivity;DNA:polymorphism: :p.M11T (human) RGD PMID:19493231 RGD:4143494 NCBI chr10:79,937,740...79,982,383
Ensembl chr10:79,937,467...79,982,614 		JBrowse link
G TAP1 transporter 1, ATP binding cassette subfamily B member susceptibility
no_association		 IAGP DNA:SNPs: : RGD PMID:17982230 PMID:12018331 RGD:6482262, RGD:6482274 NCBI chr 6:32,845,209...32,853,704
Ensembl chr 6:32,845,209...32,853,816 		JBrowse link
G TBXA2R thromboxane A2 receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:12167471 NCBI chr19:3,594,507...3,606,875
Ensembl chr19:3,594,507...3,606,875 		JBrowse link
G TGFB1 transforming growth factor beta 1 IEP associated with Sinusitis RGD PMID:18423831 RGD:4145277 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G TLR2 toll like receptor 2 susceptibility
no_association		 IAGP
IEP		 DNA:SNPs: :597T>C, 1350T>C (human)
mRNA:decreased expression:nasal mucosa:
associated with Sinusitis;DNA:SNPs: :multiple (human)		 RGD PMID:19763595 PMID:18219831 PMID:19128592 RGD:4145354, RGD:7800742, RGD:4145356 NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,070...153,706,260 		JBrowse link
G TLR6 toll like receptor 6 IAGP associated with Asthma;DNA:SNP: :rs2381289 (human) RGD PMID:20815312 RGD:4145352 NCBI chr 4:38,822,897...38,868,390
Ensembl chr 4:38,822,897...38,856,817 		JBrowse link
G TNF tumor necrosis factor IDA
ISO		 mRNA:increased expression:nose RGD PMID:15120189 PMID:20696593 RGD:4143470, RGD:4145454 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G VEGFA vascular endothelial growth factor A IEP protein:increased expression:sputum RGD PMID:19178538 RGD:6892723 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487 		JBrowse link
G VIP vasoactive intestinal peptide EXP CTD Direct Evidence: marker/mechanism CTD PMID:12746121 PMID:14680090 NCBI chr 6:152,750,797...152,759,760
Ensembl chr 6:152,750,797...152,759,765 		JBrowse link
rhinoscleroma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 susceptibility IAGP DNA:haplotype: : RGD PMID:17321882 RGD:8547664 NCBI chr 6:32,637,406...32,655,272
Ensembl chr 6:32,628,179...32,647,062 		JBrowse link
G HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 susceptibility IAGP DNA:haplotype: : RGD PMID:17321882 RGD:8547664 NCBI chr 6:32,659,467...32,666,657
Ensembl chr 6:32,659,467...32,668,383 		JBrowse link
Rhinosinusitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA1 annexin A1 IEP associated with Nasal Polyps RGD PMID:22279949 RGD:7421555 NCBI chr 9:73,151,865...73,170,393
Ensembl chr 9:73,151,865...73,170,393 		JBrowse link
G C3 complement C3 IEP protein:increased expression:serum RGD PMID:19593977 RGD:4889484 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562 		JBrowse link
G C4A complement C4A (Chido/Rodgers blood group) disease_progression IAGP DNA:deletion: : RGD PMID:16879240 RGD:5688262 NCBI chr 6:31,982,057...32,002,681
Ensembl chr 6:31,982,057...32,002,681 		JBrowse link
G CCL20 C-C motif chemokine ligand 20 IEP RGD PMID:16702571 RGD:7483585 NCBI chr 2:227,813,842...227,817,556
Ensembl chr 2:227,805,739...227,817,564 		JBrowse link
G HGF hepatocyte growth factor susceptibility IAGP DNA:haplotype::rs38850,rs38855,rs38857(human) RGD PMID:20416453 RGD:8548615 NCBI chr 7:81,699,010...81,770,047
Ensembl chr 7:81,699,010...81,770,438 		JBrowse link
G IGF1 insulin like growth factor 1 ISO mRNA:increased expression:nose: RGD PMID:20713758 RGD:8548883 NCBI chr12:102,395,874...102,481,839
Ensembl chr12:102,395,874...102,481,744 		JBrowse link
G IL10 interleukin 10 IEP protein:decreased expression:blood, mononuclear cell RGD PMID:23168151 RGD:7364820 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL17A interleukin 17A IEP associated with Asthma;mRNA, protein:increased expression:nasal polyps (human) RGD PMID:19672092 RGD:4889146 NCBI chr 6:52,186,375...52,190,638
Ensembl chr 6:52,186,375...52,190,638 		JBrowse link
G IL1B interleukin 1 beta IEP protein:increased expression:nasal cavity epithelium RGD PMID:11197112 RGD:7401169 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL22RA1 interleukin 22 receptor subunit alpha 1 susceptibility IAGP DNA:SNPs:5' utr, intron: (rs4292900, rs16829225, rs4648936) (human) RGD PMID:19393422 RGD:5147411 NCBI chr 1:24,119,771...24,143,140
Ensembl chr 1:24,119,771...24,143,140 		JBrowse link
G IL4 interleukin 4 treatment IEP associated with Asthma RGD PMID:12787306 RGD:7829803 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G MMP9 matrix metallopeptidase 9 IEP RGD PMID:23401274 RGD:8547880 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MUC5AC mucin 5AC, oligomeric mucus/gel-forming treatment ISO RGD PMID:23131200 PMID:19389874 RGD:7349403, RGD:7364734 NCBI chr11:1,157,953...1,201,138
Ensembl chr11:1,157,953...1,201,138 		JBrowse link
G PRKRA protein activator of interferon induced protein kinase EIF2AK2 severity IEP associated with Nasal Polyps RGD PMID:22961479 RGD:7777146 NCBI chr 2:178,431,414...178,451,175
Ensembl chr 2:178,431,292...178,451,512 		JBrowse link
G SERPINE1 serpin family E member 1 IEP protein:increased expression:nasal mucosa (human) RGD PMID:21711960 RGD:6483796 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247 		JBrowse link
G TLR2 toll like receptor 2 susceptibility IEP
IAGP		 mRNA,protein:increased expression:paranasal sinus
DNA:polymorphisms:: rs3804099,rs3804100(human)		 RGD PMID:22182736 PMID:21493395 RGD:7800733, RGD:8552975 NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,070...153,706,260 		JBrowse link
G TLR4 toll like receptor 4 IEP mRNA,protein:increased expression:paranasal sinus RGD PMID:22182736 RGD:7800733 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G TNF tumor necrosis factor IEP
ISO		 protein:increased expression:nasal cavity epithelium RGD PMID:11197112 PMID:20147558 RGD:7401169, RGD:7401236 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
Rhinosinusitis, Allergic Fungal term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 IAGP DNA:polymorphisms, haplotypes:cds:HLA-DQB1*0301, HLA-DQB1*0302 (human) RGD PMID:15577839 RGD:5147654 NCBI chr 6:32,659,467...32,666,657
Ensembl chr 6:32,659,467...32,668,383 		JBrowse link
Seasonal Allergic Rhinitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX5 arachidonate 5-lipoxygenase IEP RGD PMID:16677242 RGD:5147463 NCBI chr10:45,374,216...45,446,117
Ensembl chr10:45,374,176...45,446,119 		JBrowse link
G APOA4 apolipoprotein A4 resistance IEP protein:increased expression:blood serum (human) RGD PMID:20810159 RGD:5685642 NCBI chr11:116,820,700...116,823,304
Ensembl chr11:116,820,700...116,823,304 		JBrowse link
G BDNF brain derived neurotrophic factor severity IEP protein:increased expression:blood, nasal cavity epithelium RGD PMID:18266897 RGD:5144117 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 IEP protein:increased expression:inferior turbinate, epithelium (human) RGD PMID:20459697 RGD:4891379 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793 		JBrowse link
G CMA1 chymase 1 IEP protein:increased expression:nasal mucosa, mast cell (human) RGD PMID:11549546 RGD:5128839 NCBI chr14:24,505,353...24,508,265
Ensembl chr14:24,505,353...24,508,265 		JBrowse link
G CST1 cystatin SN EXP CTD Direct Evidence: marker/mechanism CTD PMID:23950865 NCBI chr20:23,747,562...23,750,935
Ensembl chr20:23,747,562...23,751,268 		JBrowse link
G FGA fibrinogen alpha chain IDA RGD PMID:21887273 RGD:5688767 NCBI chr 4:154,583,126...154,590,742
Ensembl chr 4:154,583,126...154,590,742 		JBrowse link
G GSTO1 glutathione S-transferase omega 1 IEP protein:decreased expression;T lymphocyte: RGD PMID:21410266 RGD:5491008 NCBI chr10:104,254,173...104,267,455
Ensembl chr10:104,235,356...104,267,459 		JBrowse link
G HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 susceptibility IAGP DNA:polymorphism:cds:HLA-DQB1*05 (human)
DNA:polymorphisms, haplotype:cds:HLA-DQB1*0301, HLA-DQB1*0501 (human)		 RGD PMID:22032123 PMID:9641569 RGD:7421561, RGD:7421576 NCBI chr 6:32,659,467...32,666,657
Ensembl chr 6:32,659,467...32,668,383 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 IEP protein:increased secretion:nasopharynx, secretion (human) RGD PMID:20128420 RGD:4145459 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615 		JBrowse link
G IFNGR1 interferon gamma receptor 1 IAGP DNA: SNP: Leu467Pro RGD PMID:12851715 RGD:6480431 NCBI chr 6:137,197,484...137,219,385
Ensembl chr 6:137,197,483...137,219,449 		JBrowse link
G IL10 interleukin 10 treatment IEP RGD PMID:19505388 RGD:7365025 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL18 interleukin 18 susceptibility
no_association		 IAGP DNA:SNPs:promoters, exon:multiple
DNA:SNPs:promoters:multiple		 RGD PMID:12532106 PMID:12532106 RGD:8655871, RGD:8655871 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096 		JBrowse link
G IL4 interleukin 4 IEP protein:increased expression:serum
mRNA:increased expression:nose:		 RGD PMID:9237816 PMID:7551298 RGD:7829817, RGD:8662960 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G KDR kinase insert domain receptor IEP protein:increased expression:nasal cavity of mucosa: RGD PMID:17651148 RGD:8551771 NCBI chr 4:55,078,481...55,125,595
Ensembl chr 4:55,078,481...55,125,595 		JBrowse link
G MC1R melanocortin 1 receptor no_association ISO RGD PMID:20357480 RGD:5687317 NCBI chr16:89,918,862...89,920,972
Ensembl chr16:89,912,119...89,920,973 		JBrowse link
G MMP9 matrix metallopeptidase 9 IAGP DNA:SNPs:promoter, intron, cds:-1590C>T, 2127G>T, p.R668Q (rs3918242, rs2274755, rs17577) (human) RGD PMID:22237587 RGD:8547819 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G NOD1 nucleotide binding oligomerization domain containing 1 susceptibility IAGP DNA:SNP: :rs2075817 (human) RGD PMID:16918516 RGD:5131519 NCBI chr 7:30,424,527...30,478,784
Ensembl chr 7:30,424,527...30,478,784 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 susceptibility IAGP DNA:polymorphisms:5'UTR/exon, exon:rs5743266, rs2066842 (human) RGD PMID:16008671 RGD:5131477 NCBI chr16:50,693,606...50,733,075
Ensembl chr16:50,693,588...50,733,077 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 IEP protein:increased expression:respiratory system epithelium RGD PMID:19364335 RGD:5147461 NCBI chr 9:122,370,533...122,395,703
Ensembl chr 9:122,370,530...122,395,703 		JBrowse link
G SCGB1A1 secretoglobin family 1A member 1 IEP mRNA, protein:decreased expression:nasal lavage fluid RGD PMID:15836756 RGD:5144234 NCBI chr11:62,419,033...62,423,195
Ensembl chr11:62,405,103...62,423,195 		JBrowse link
G TLR3 toll like receptor 3 IEP protein:decreased expression:bone marrow, blood, eosinophil (human) RGD PMID:19752565 RGD:5129130 NCBI chr 4:186,069,156...186,088,073
Ensembl chr 4:186,068,911...186,088,073 		JBrowse link
G TLR4 toll like receptor 4 susceptibility IAGP DNA:polymorphisms:cds:p.D299G, T399I (human) RGD PMID:18517079 RGD:4144192 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G VEGFA vascular endothelial growth factor A IEP mRNA,protein:increased expression:nasal biopsies,nasal lavage fluid: RGD PMID:12633568 RGD:7483595 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487 		JBrowse link
severe acute respiratory syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABO ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase susceptibility IAGP RGD PMID:15784866 RGD:5128832 NCBI chr 9:133,250,401...133,275,201
Ensembl chr 9:133,233,278...133,276,024 		JBrowse link
G ACE angiotensin I converting enzyme EXP CTD Direct Evidence: marker/mechanism CTD PMID:15381116 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380 		JBrowse link
G ACE2 angiotensin converting enzyme 2 treatment
susceptibility
severity		 EXP
ISO
IMP		 CTD Direct Evidence: marker/mechanism
mRNA, protein:decreased expression:heart (mouse)
human gene in a mouse model		 CTD
RGD		 PMID:14647384 PMID:16007097 PMID:16166518 PMID:16339146 PMID:19453650 More... RGD:40818405, RGD:32716426, RGD:30309965, RGD:30309202 NCBI chr  X:15,518,197...15,607,211
Ensembl chr  X:15,494,566...15,607,236 		JBrowse link
G ANPEP alanyl aminopeptidase, membrane disease_progression IEP mRNA:increased expression:lung (human) RGD PMID:19635508 RGD:5490168 NCBI chr15:89,784,895...89,814,852
Ensembl chr15:89,784,895...89,815,401 		JBrowse link
G BPI bactericidal permeability increasing protein disease_progression IEP mRNA:increased expression:lung (human) RGD PMID:19635508 RGD:5490168 NCBI chr20:38,304,156...38,337,505
Ensembl chr20:38,304,150...38,337,505 		JBrowse link
G C1QB complement C1q B chain disease_progression IEP mRNA:increased expression:lung (human) RGD PMID:19635508 RGD:5490168 NCBI chr 1:22,653,236...22,661,637
Ensembl chr 1:22,652,762...22,661,637 		JBrowse link
G C5AR1 complement C5a receptor 1 disease_progression IEP mRNA:increased expression:lung (human) RGD PMID:19635508 RGD:5490168 NCBI chr19:47,307,477...47,322,066
Ensembl chr19:47,290,023...47,322,066 		JBrowse link
G CASP3 caspase 3 disease_progression IEP mRNA:increased expression:lung (human) RGD PMID:19635508 RGD:5490168 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP9 caspase 9 disease_progression IEP mRNA:increased expression:lung (human) RGD PMID:19635508 RGD:5490168 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534 		JBrowse link
G CCL1 C-C motif chemokine ligand 1 ISO mRNA: increased expression:lung (mouse) RGD PMID:15356152 RGD:30309221 NCBI chr17:34,360,328...34,363,233
Ensembl chr17:34,360,328...34,363,233 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 treatment
severity		 EXP
IEP
ISO		 CTD Direct Evidence: marker/mechanism
protein:increased expression:bronchoalveolar lavage (human)
protein:increased expression:serum (human)
mRNA, protein: increased expression, altered expression:lung (mouse)
protein:increased expression:plasma (human)		 CTD
RGD		 PMID:20484496 PMID:15888207 PMID:32553273 PMID:15602737 PMID:15356152 More... RGD:34201108, RGD:32716426, RGD:32716399, RGD:30309221, RGD:30309220, RGD:30309219, RGD:30309218 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CCL3 C-C motif chemokine ligand 3 ISO mRNA, protein: increased expression, altered expression:lung (mouse) RGD PMID:15356152 RGD:30309221 NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 severity
treatment		 IAGP
IEP
ISO		 Severe Acute Respiratory Syndrome; DNA:transversion:5' utr:-28C>G (human)
protein:increased expression:bronchoalveolar lavage (human)
mRNA, protein: increased expression, altered expression:lung, brain (mouse)
protein:increased expression:plasma (human)
mRNA:increased expression:lung (mouse)		 RGD PMID:19258635 PMID:15888207 PMID:15865221 PMID:32553273 PMID:15356152 More... RGD:4891448, RGD:34201108, RGD:33769580, RGD:32716426, RGD:30309221, RGD:30309220, RGD:30309218, RGD:30309207 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793 		JBrowse link
G CCR1 C-C motif chemokine receptor 1 ISO mRNA:increased expression:lung (mouse) RGD PMID:15356152 RGD:30309221 NCBI chr 3:46,201,711...46,208,313
Ensembl chr 3:46,201,711...46,208,313 		JBrowse link
G CCR3 C-C motif chemokine receptor 3 ISO mRNA:altered expression:lung (mouse) RGD PMID:15356152 RGD:30309221 NCBI chr 3:46,210,696...46,266,706
Ensembl chr 3:46,130,890...46,266,706 		JBrowse link
G CD14 CD14 molecule disease_progression IEP mRNA:increased expression:lung (human) RGD PMID:19635508 RGD:5490168 NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,700 		JBrowse link
G CD3E CD3 epsilon subunit of T-cell receptor complex IEP protein:increased expression:Tcell, testis (human) RGD PMID:16237152 RGD:27372876 NCBI chr11:118,304,730...118,316,173
Ensembl chr11:118,304,730...118,316,175 		JBrowse link
G CD4 CD4 molecule disease_progression IEP mRNA:increased expression:lung (human) RGD PMID:19635508 RGD:5490168 NCBI chr12:6,789,528...6,820,799
Ensembl chr12:6,786,858...6,820,799 		JBrowse link
G CD68 CD68 molecule disease_progression IEP mRNA, protein:increased expression:lung (human)
protein:increased expression:macrophage, testis (human)		 RGD PMID:19635508 PMID:16237152 RGD:5490168, RGD:27372876 NCBI chr17:7,579,638...7,582,111
Ensembl chr17:7,579,491...7,582,111 		JBrowse link
G CD9 CD9 molecule disease_progression IEP mRNA, protein:increased expression:lung (human) RGD PMID:19635508 RGD:5490168 NCBI chr12:6,199,946...6,238,266
Ensembl chr12:6,199,715...6,238,271 		JBrowse link
G CEACAM8 CEA cell adhesion molecule 8 disease_progression IEP mRNA:increased expression:lung (human) RGD PMID:19635508 RGD:5490168 NCBI chr19:42,580,243...42,594,924
Ensembl chr19:42,580,243...42,595,055 		JBrowse link
G CLCF1 cardiotrophin like cytokine factor 1 disease_progression IEP mRNA:decreased expression:lung (human) RGD PMID:19635508 RGD:5490168 NCBI chr11:67,364,168...67,374,177
Ensembl chr11:67,364,168...67,374,177 		JBrowse link
G CLEC4M C-type lectin domain family 4 member M susceptibility
no_association		 IAGP DNA:repeats:exon 4: RGD PMID:16369534 PMID:18708672 PMID:17534355 PMID:17534354 RGD:35673327, RGD:36049808, RGD:36049807, RGD:36049806 NCBI chr19:7,763,243...7,769,605
Ensembl chr19:7,763,210...7,769,605 		JBrowse link
G CTSL cathepsin L EXP CTD Direct Evidence: marker/mechanism CTD PMID:16081529 PMID:16339146 PMID:22496216 PMID:23678171 NCBI chr 9:87,726,119...87,731,469
Ensembl chr 9:87,724,051...87,731,469 		JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 ISO protein:increased expression:respiratory system fluid/secretion RGD PMID:19741068 RGD:4143520 NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308 		JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 treatment
severity
disease_progression		 IEP
ISO		 protein:increased expression:serum
protein:increased expression:serum (human)
mRNA, protein: increased expression, altered expression:lung (mouse)
mRNA, protein:increased expression:serum, lung (human)
mRNA, protein:increased expression:plasma, lung (human)
protein:increased expression:lung (human)
protein:increased expression:lung (mouse)
mRNA:increased expression:lung (mouse)
mRNA:decreased expression:lung (human)		 RGD PMID:17052299 PMID:15865221 PMID:32553273 PMID:15602737 PMID:15356152 More... RGD:5135440, RGD:33769580, RGD:32716426, RGD:32716399, RGD:30309221, RGD:30309220, RGD:30309219, RGD:30309218, RGD:30309217, RGD:30309216, RGD:30309207, RGD:5490168 NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497 		JBrowse link
G CXCL11 C-X-C motif chemokine ligand 11 treatment ISO RGD PMID:32553273 RGD:32716426 NCBI chr 4:76,033,682...76,036,070
Ensembl chr 4:76,033,682...76,041,415 		JBrowse link
G CXCL5 C-X-C motif chemokine ligand 5 ISO protein:increased expression:respiratory fluid/secretion RGD PMID:19741068 RGD:4143520 NCBI chr 4:73,995,642...73,998,677
Ensembl chr 4:73,995,642...73,998,677 		JBrowse link
G CXCL6 C-X-C motif chemokine ligand 6 ISO protein:increased expression:respiratory fluid/secretion
mRNA:decreased expression:lung (mouse)		 RGD PMID:19741068 PMID:32364527 RGD:27226699 RGD:4143520 NCBI chr 4:73,836,678...73,838,760
Ensembl chr 4:73,836,640...73,849,064 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 disease_progression
treatment
severity		 IEP mRNA:increased expression:lung (human)
protein:increased expression:serum (human)
protein:increased expression:blood (human)
protein:increased expression:bronchoalveolar lavage (human)
protein:increased expression:plasma (human)		 RGD PMID:19635508 PMID:15271897 PMID:15472864 PMID:15888207 PMID:15865221 More... RGD:5490168, RGD:32716401, RGD:34888224, RGD:34201108, RGD:33769580, RGD:30309961, RGD:30309219, RGD:30309218 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CXCL9 C-X-C motif chemokine ligand 9 severity
treatment		 ISO
IEP		 mRNA, protein:increased expression:lung
protein:increased expression:bronchoalveolar lavage (human)
protein:increased expression:plasma (human)
protein:increased expression:serum (human)
mRNA, protein: increased expression, altered expression:lung (mouse)		 RGD PMID:19906920 PMID:15888207 PMID:16195357 PMID:15602737 PMID:15356152 More... RGD:4891446, RGD:34201108, RGD:30309218, RGD:32716399, RGD:30309221, RGD:30309220 NCBI chr 4:76,001,275...76,007,509
Ensembl chr 4:76,001,275...76,007,509 		JBrowse link
G CXCR3 C-X-C motif chemokine receptor 3 ISO mRNA:altered expression:lung (mouse) RGD PMID:15356152 RGD:30309221 NCBI chr  X:71,615,919...71,618,511
Ensembl chr  X:71,615,916...71,618,511 		JBrowse link
G EGFR epidermal growth factor receptor severity ISO RGD PMID:28404843 RGD:38599178 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G FGB fibrinogen beta chain ISO protein:increased expression:lung (mouse) RGD PMID:23919993 RGD:30310231 NCBI chr 4:154,562,980...154,572,807
Ensembl chr 4:154,563,011...154,572,807 		JBrowse link
G FGF7 fibroblast growth factor 7 disease_progression IEP mRNA:increased expression:lung (human) RGD PMID:19635508 RGD:5490168 NCBI chr15:49,423,242...49,488,775
Ensembl chr15:49,423,237...49,488,775 		JBrowse link
G FGG fibrinogen gamma chain ISO protein:increased expression:lung (mouse) RGD PMID:23919993 RGD:30310231 NCBI chr 4:154,604,136...154,612,656
Ensembl chr 4:154,604,134...154,612,967 		JBrowse link
G FN1 fibronectin 1 ISO protein:increased expression:lung (mouse) RGD PMID:23919993 RGD:30310231 NCBI chr 2:215,360,865...215,436,068
Ensembl chr 2:215,360,440...215,436,073 		JBrowse link
G FSHB follicle stimulating hormone subunit beta IEP protein:increased expression:adenohypophysis (human) RGD PMID:20651845 RGD:28711759 NCBI chr11:30,231,014...30,235,194
Ensembl chr11:30,231,014...30,235,261 		JBrowse link
G GH1 growth hormone 1 IEP protein:decreased expression:adenohypophysis (human) RGD PMID:20651845 RGD:28711759 NCBI chr17:63,917,203...63,918,839
Ensembl chr17:63,917,200...63,918,839 		JBrowse link
G HLA-B major histocompatibility complex, class I, B severity IAGP DNA:polymorphism:cds:HLA-B*0703 (human)
DNA:polymorphism:cds:HLA-B*4601 (human)		 RGD PMID:15243926 PMID:12969506 RGD:32716381, RGD:32716382 NCBI chr 6:31,353,875...31,357,179
Ensembl chr 6:31,353,872...31,367,067 		JBrowse link
G HLA-DRA major histocompatibility complex, class II, DR alpha disease_progression IEP mRNA:increased expression:lung RGD PMID:19635508 RGD:5490168 NCBI chr 6:32,439,887...32,445,046
Ensembl chr 6:32,439,878...32,445,046 		JBrowse link
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 IAGP DNA:polymorphism:cds:HLA-DRB1*12 (human)
DNA:polymorphism:cds:HLA-DRB1*0301 (human)		 RGD PMID:19445991 PMID:15243926 RGD:32716374, RGD:32716381 NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,577,902...32,589,848 		JBrowse link
G HP haptoglobin disease_progression IEP mRNA:increased expression:lung (human) RGD PMID:19635508 RGD:5490168 NCBI chr16:72,054,505...72,061,055
Ensembl chr16:72,054,505...72,061,055 		JBrowse link
G IFNA1 interferon alpha 1 EXP CTD Direct Evidence: therapeutic CTD PMID:15200845 NCBI chr 9:21,440,439...21,441,316
Ensembl chr 9:21,440,439...21,441,316 		JBrowse link
G IFNB1 interferon beta 1 treatment EXP
ISO		 CTD Direct Evidence: marker/mechanism|therapeutic CTD
RGD		 PMID:15200845 PMID:26861016 PMID:32553273 RGD:32716426 NCBI chr 9:21,077,104...21,077,942
Ensembl chr 9:21,077,104...21,077,942 		JBrowse link
G IFNG interferon gamma susceptibility
treatment		 IAGP
IEP		 DNA:polymorphism:cds:+874A>T(human)
protein:increased expression:peripheral blood mononuclear cells (human)
protein:increased expression:serum (human)
DNA:SNP:intron:+874A>T (rs2430561)(human)		 RGD PMID:19258635 PMID:15865221 PMID:16781892 PMID:15602737 PMID:16672072 More... RGD:4891448, RGD:33769580, RGD:32716400, RGD:32716399, RGD:32716398, RGD:32716397, RGD:32716396 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IGF1 insulin like growth factor 1 disease_progression IEP mRNA:increased expression:lung (human) RGD PMID:19635508 RGD:5490168 NCBI chr12:102,395,874...102,481,839
Ensembl chr12:102,395,874...102,481,744 		JBrowse link
G IL10 interleukin 10 treatment ISO
IEP		 protein:increased expression:serum, bronchoalveolar Lavage fluid (rat) RGD PMID:16409721 PMID:15865221 RGD:32726073, RGD:33769580 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL18 interleukin 18 IEP protein:increased expression:serum (human) RGD PMID:15602737 RGD:32716399 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096 		JBrowse link
G IL1A interleukin 1 alpha ISO mRNA:altered expression:lung (mouse) RGD PMID:32364527 RGD:27226699 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493 		JBrowse link
G IL1B interleukin 1 beta severity ISO mRNA:altered expression:lung (mouse)
mRNA, protein:increased expression:lung, bronchoalveolar lavage (mouse)		 RGD PMID:32364527 PMID:32365944 RGD:27226699, RGD:30309207 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL1R1 interleukin 1 receptor type 1 disease_progression IEP mRNA:increased expression:lung (human) RGD PMID:19635508 RGD:5490168 NCBI chr 2:102,070,390...102,179,874
Ensembl chr 2:102,064,544...102,179,874 		JBrowse link
G IL23A interleukin 23 subunit alpha ISO mRNA:decreased expression:lung (mouse) RGD PMID:32364527 RGD:27226699 NCBI chr12:56,338,884...56,340,410
Ensembl chr12:56,334,174...56,340,410 		JBrowse link
G IL6 interleukin 6 severity
disease_progression
treatment		 IEP
ISO		 protein:increased expression:serum (human)
protein:increased expression:blood (human)
protein:increased expression:bronchoalveolar lavage (human)
protein:increased expression:serum, Bronchoalveolar Lavage fluid (rat)		 RGD PMID:15657466 PMID:15472864 PMID:15888207 PMID:15865221 PMID:16409721 More... RGD:30309219, RGD:34888224, RGD:34201108, RGD:33769580, RGD:32726073, RGD:32716426, RGD:32716401 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G IL7 interleukin 7 ISO mRNA:decreased expression:lung (mouse) RGD PMID:32364527 RGD:27226699 NCBI chr 8:78,675,044...78,805,463
Ensembl chr 8:78,675,743...78,805,523 		JBrowse link
G IRF3 interferon regulatory factor 3 disease_progression EXP
IEP		 CTD Direct Evidence: marker/mechanism
mRNA:increased expression:lung (human)		 CTD
RGD		 PMID:26861016 PMID:19635508 RGD:5490168 NCBI chr19:49,659,572...49,665,857
Ensembl chr19:49,659,569...49,665,875 		JBrowse link
G ITGA2B integrin subunit alpha 2b disease_progression IEP mRNA:decreased expression:lung (human) RGD PMID:19635508 RGD:5490168 NCBI chr17:44,372,181...44,389,649
Ensembl chr17:44,372,180...44,389,649 		JBrowse link
G KRT7 keratin 7 ISO protein:increased expression:lung (mouse) RGD PMID:23919993 RGD:30310231 NCBI chr12:52,233,243...52,255,853
Ensembl chr12:52,232,520...52,252,186 		JBrowse link
G LHB luteinizing hormone subunit beta IEP protein:increased expression:adenohypophysis (human) RGD PMID:20651845 RGD:28711759 NCBI chr19:49,015,980...49,019,498
Ensembl chr19:49,015,980...49,017,091 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20484496 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20484496 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MSR1 macrophage scavenger receptor 1 disease_progression IEP mRNA:increased expression:lung (human) RGD PMID:19635508 RGD:5490168 NCBI chr 8:16,107,881...16,192,651
Ensembl chr 8:16,107,878...16,567,490 		JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:26861016 NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,552...38,143,024 		JBrowse link
G NFIL3 nuclear factor, interleukin 3 regulated disease_progression IEP mRNA:increased expression:lung (human) RGD PMID:19635508 RGD:5490168 NCBI chr 9:91,409,045...91,483,497
Ensembl chr 9:91,409,045...91,423,832 		JBrowse link
G NLRP3 NLR family pyrin domain containing 3 ISO RGD PMID:32365944 RGD:30309207 NCBI chr 1:247,416,077...247,448,817
Ensembl chr 1:247,416,156...247,449,108 		JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 disease_progression IEP mRNA, protein:increased expression:lung (human) RGD PMID:19635508 RGD:5490168 NCBI chr17:64,319,415...64,390,860
Ensembl chr17:64,319,415...64,413,776 		JBrowse link
G PI4KB phosphatidylinositol 4-kinase beta EXP CTD Direct Evidence: marker/mechanism CTD PMID:22253445 NCBI chr 1:151,291,797...151,327,715
Ensembl chr 1:151,291,797...151,327,715 		JBrowse link
G PLAT plasminogen activator, tissue type IEP protein:increased expression:plasma (human) RGD PMID:16274108 RGD:30309949 NCBI chr 8:42,174,718...42,207,565
Ensembl chr 8:42,174,718...42,207,709 		JBrowse link
G PLG plasminogen ISO protein:increased expression:lung (mouse) RGD PMID:23919993 RGD:30310231 NCBI chr 6:160,702,193...160,754,097
Ensembl chr 6:160,702,194...160,754,097 		JBrowse link
G POMC proopiomelanocortin IEP protein:decreased expression:adenohypophysis (human) RGD PMID:20651845 RGD:28711759 NCBI chr 2:25,160,860...25,168,580
Ensembl chr 2:25,160,853...25,168,903 		JBrowse link
G PRL prolactin IEP protein:increased expression:adenohypophysis (human) RGD PMID:20651845 RGD:28711759 NCBI chr 6:22,287,246...22,302,835
Ensembl chr 6:22,287,244...22,302,826 		JBrowse link
G RAB31 RAB31, member RAS oncogene family disease_progression IEP mRNA:increased expression:lung (human) RGD PMID:19635508 RGD:5490168 NCBI chr18:9,708,301...9,862,551
Ensembl chr18:9,708,275...9,862,551 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit EXP CTD Direct Evidence: marker/mechanism CTD PMID:26861016 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G S100A8 S100 calcium binding protein A8 disease_progression IEP mRNA:increased expression:lung (human) RGD PMID:19635508 RGD:5490168 NCBI chr 1:153,390,032...153,422,583
Ensembl chr 1:153,390,032...153,391,073 		JBrowse link
G SERPINA3 serpin family A member 3 IEP protein:increased expression:plasma RGD PMID:16649161 RGD:5147434 NCBI chr14:94,612,391...94,624,053
Ensembl chr14:94,612,384...94,624,055 		JBrowse link
G SLPI secretory leukocyte peptidase inhibitor disease_progression IEP mRNA:increased expression:lung (human) RGD PMID:19635508 RGD:5490168 NCBI chr20:45,252,239...45,254,564
Ensembl chr20:45,252,239...45,254,564 		JBrowse link
G STAT1 signal transducer and activator of transcription 1 ISS MouseDO NCBI chr 2:190,969,149...191,014,171
Ensembl chr 2:190,908,460...191,020,960 		JBrowse link
G TBK1 TANK binding kinase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26861016 NCBI chr12:64,452,120...64,502,114
Ensembl chr12:64,452,090...64,502,114 		JBrowse link
G TGFB1 transforming growth factor beta 1 IEP
ISO		 protein:increased expression:serum (human)
protein:increased expression:serum, bronchoalveolar Lavage fluid (rat)		 RGD PMID:15271897 PMID:16409721 RGD:32716401, RGD:32726073 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G THBD thrombomodulin IEP protein:increased expression:plasma (human) RGD PMID:16274108 RGD:30309949 NCBI chr20:23,045,633...23,049,672
Ensembl chr20:23,045,633...23,049,672 		JBrowse link
G TICAM2 TIR domain containing adaptor molecule 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26861016 NCBI chr 5:115,578,496...115,602,479
Ensembl chr 5:115,578,496...115,602,479 		JBrowse link
G TIRAP TIR domain containing adaptor protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:26861016 NCBI chr11:126,283,093...126,294,933
Ensembl chr11:126,282,497...126,298,845 		JBrowse link
G TLR2 toll like receptor 2 disease_progression IEP mRNA:increased expression:lung (human) RGD PMID:19635508 RGD:5490168 NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,070...153,706,260 		JBrowse link
G TMPRSS11D transmembrane serine protease 11D EXP CTD Direct Evidence: marker/mechanism CTD PMID:24227843 NCBI chr 4:67,820,876...67,884,002
Ensembl chr 4:67,820,876...67,884,002 		JBrowse link
G TMPRSS2 transmembrane serine protease 2 severity ISO RGD PMID:30626688 RGD:30309210 NCBI chr21:41,529,791...41,531,118
Ensembl chr21:41,464,300...41,531,116 		JBrowse link
G TMPRSS2 transmembrane serine protease 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22496216 PMID:24227843 PMID:30626688 NCBI chr21:41,464,305...41,508,158
Ensembl chr21:41,464,300...41,531,116 		JBrowse link
G TNF tumor necrosis factor IEP protein:increased expression:plasma (human)
protein:increased expression:bronchoalveolar lavage (human)		 RGD PMID:14514395 PMID:15888207 RGD:30309961, RGD:34201108 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TSHB thyroid stimulating hormone subunit beta IEP protein:decreased expression:adenohypophysis (human) RGD PMID:20651845 RGD:28711759 NCBI chr 1:115,029,826...115,034,309
Ensembl chr 1:115,029,826...115,034,302 		JBrowse link
G VIM vimentin EXP CTD Direct Evidence: marker/mechanism CTD PMID:26801988 NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593 		JBrowse link
G VWF von Willebrand factor ISO protein:increased expression:lung (mouse) RGD PMID:23919993 RGD:30310231 NCBI chr12:5,948,877...6,124,670
Ensembl chr12:5,948,877...6,124,770 		JBrowse link
G XCL1 X-C motif chemokine ligand 1 ISO mRNA:increased expression:lung (mouse) RGD PMID:15356152 RGD:30309221 NCBI chr 1:168,576,605...168,582,069
Ensembl chr 1:168,576,605...168,582,069 		JBrowse link
Silicotuberculosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G STING1 stimulator of interferon response cGAMP interactor 1 severity ISO RGD PMID:31141689 RGD:39128194 NCBI chr 5:139,475,533...139,482,758
Ensembl chr 5:139,475,533...139,482,935 		JBrowse link
sinusitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AZGP1 alpha-2-glycoprotein 1, zinc-binding EXP CTD Direct Evidence: marker/mechanism CTD PMID:18391768 NCBI chr 7:99,966,730...99,976,031
Ensembl chr 7:99,966,720...99,976,042 		JBrowse link
G CCL4 C-C motif chemokine ligand 4 IEP RGD PMID:19786211 RGD:5130914 NCBI chr17:36,103,827...36,105,614
Ensembl chr17:36,103,827...36,105,621 		JBrowse link
G CFB complement factor B IEP protein:decreased expression:serum RGD PMID:14510109 RGD:7411729 NCBI chr 6:31,946,095...31,952,084
Ensembl chr 6:31,945,650...31,952,086 		JBrowse link
G CFTR CF transmembrane conductance regulator susceptibility IAGP
EXP		 DNA:mutations: :
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:16083808 PMID:11773581 RGD:4140477 NCBI chr 7:117,480,025...117,668,665
Ensembl chr 7:117,287,120...117,715,971 		JBrowse link
G CHIA chitinase acidic severity IEP mRNA:decreased expression:sinus, epithelial cell (human) RGD PMID:19379605 RGD:5037227 NCBI chr 1:111,290,851...111,320,563
Ensembl chr 1:111,290,851...111,320,566 		JBrowse link
G CXCL5 C-X-C motif chemokine ligand 5 IEP associated with Rhinitis;mRNA:increased expression:paranasal sinus RGD PMID:19153309 RGD:5135257 NCBI chr 4:73,995,642...73,998,677
Ensembl chr 4:73,995,642...73,998,677 		JBrowse link
G IL13 interleukin 13 susceptibility IAGP
EXP		 associated with asthma; DNA:polymorphisms:promoter:c. -1510A>C, -1055C>T (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:20358028 PMID:20358028 RGD:4145767 NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110 		JBrowse link
G IL1B interleukin 1 beta IEP associated with Hypersensitivity RGD PMID:16358839 RGD:4143214 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL2 interleukin 2 IEP RGD PMID:11758471 RGD:8662964 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725 		JBrowse link
G LTA lymphotoxin alpha susceptibility IAGP DNA:polymorphism: : RGD PMID:11037831 RGD:4143260 NCBI chr 6:31,560,610...31,574,324
Ensembl chr 6:31,572,054...31,574,324 		JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase EXP CTD Direct Evidence: marker/mechanism CTD PMID:18391768 NCBI chr 7:116,672,196...116,798,377
Ensembl chr 7:116,672,196...116,798,377 		JBrowse link
G MMP9 matrix metallopeptidase 9 IEP protein:increased expression: : RGD PMID:20392482 RGD:5130763 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MUC5B mucin 5B, oligomeric mucus/gel-forming IEP protein:increased secretion:sinus mucus RGD PMID:17063754 RGD:5131192 NCBI chr11:1,223,066...1,262,172
Ensembl chr11:1,223,066...1,262,172 		JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 IEP RGD PMID:18396779 RGD:4892328 NCBI chr 5:143,277,931...143,435,512
Ensembl chr 5:143,277,931...143,435,512 		JBrowse link
G PDGFB platelet derived growth factor subunit B IEP protein: increased expression: nasal cavity epithelium RGD PMID:21255638 RGD:6483060 NCBI chr22:39,223,359...39,244,982
Ensembl chr22:39,223,359...39,244,982 		JBrowse link
G PIP prolactin induced protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:18391768 NCBI chr 7:143,132,077...143,139,739
Ensembl chr 7:143,132,077...143,139,739 		JBrowse link
G PLAU plasminogen activator, urokinase IEP RGD PMID:21711960 RGD:6483796 NCBI chr10:73,909,164...73,917,494
Ensembl chr10:73,909,177...73,917,496 		JBrowse link
G PLAUR plasminogen activator, urokinase receptor IEP RGD PMID:21711960 RGD:6483796 NCBI chr19:43,646,095...43,670,169
Ensembl chr19:43,646,095...43,670,547 		JBrowse link
G PPP1R9B protein phosphatase 1 regulatory subunit 9B EXP CTD Direct Evidence: marker/mechanism CTD PMID:18391768 NCBI chr17:50,133,737...50,150,677
Ensembl chr17:50,133,737...50,150,677 		JBrowse link
G SCGB3A2 secretoglobin family 3A member 2 IEP mRNA,protein:decreased expression:nasal mucosa RGD PMID:21385388 RGD:5147389 NCBI chr 5:147,878,711...147,882,191
Ensembl chr 5:147,870,682...147,882,191 		JBrowse link
G SFTPA1 surfactant protein A1 IEP associated with Cystic Fibrosis;mRNA:increased expression:respiratory system mucosa RGD PMID:17599561 RGD:4143506 NCBI chr10:79,610,939...79,615,455
Ensembl chr10:79,610,939...79,615,455 		JBrowse link
G SFTPD surfactant protein D IEP associated with Cystic Fibrosis;mRNA:increased expression:respiratory system mucosa RGD PMID:17599561 RGD:4143506 NCBI chr10:79,937,740...79,982,383
Ensembl chr10:79,937,467...79,982,614 		JBrowse link
G TLR2 toll like receptor 2 IEP mRNA:increased expression:nasal cavity epithelium: RGD PMID:14743629 RGD:8552991 NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,070...153,706,260 		JBrowse link
G TLR4 toll like receptor 4 ISO
IEP		 associated with Pneumococal Infections;
mRNA:increased expression:nasal cavity epithelium:		 RGD PMID:16301373 PMID:14743629 RGD:7800729, RGD:8552991 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G TLR9 toll like receptor 9 IEP Acute Sinusitis; protein:decreased expression:nasal mucosa, epithelial cell (human)
Chronic Sinusitis; protein:decreased expression:nasal mucosa, epithelial cell (human)		 RGD PMID:18416964 PMID:17283572 RGD:5130708, RGD:5130870 NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,225,645 		JBrowse link
Staphylococcal Pneumonia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 treatment ISO RGD PMID:23613163 RGD:38676477 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751 		JBrowse link
G CD86 CD86 molecule ISO protein:decreased expression:spleen, plasmacytoid dendritic cell (mouse) RGD PMID:20949109 RGD:4892562 NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139 		JBrowse link
G CFTR CF transmembrane conductance regulator ISO RGD PMID:28289144 RGD:36049750 NCBI chr 7:117,480,025...117,668,665
Ensembl chr 7:117,287,120...117,715,971 		JBrowse link
G CSF3 colony stimulating factor 3 treatment IDA RGD PMID:10228098 RGD:11039478 NCBI chr17:40,015,440...40,017,813
Ensembl chr17:40,015,361...40,017,813 		JBrowse link
G FN1 fibronectin 1 ISO RGD PMID:12065530 RGD:7205474 NCBI chr 2:215,360,865...215,436,068
Ensembl chr 2:215,360,440...215,436,073 		JBrowse link
G IFNAR1 interferon alpha and beta receptor subunit 1 susceptibility ISO RGD PMID:19603548 PMID:19603548 RGD:5490273, RGD:5490273 NCBI chr21:33,324,395...33,359,864
Ensembl chr21:33,324,387...33,359,864 		JBrowse link
G IL10 interleukin 10 ISO mRNA, protein:increased expression:lung RGD PMID:22940620 RGD:7364825 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL15 interleukin 15 ISO RGD PMID:18390740 RGD:4996474 NCBI chr 4:141,636,583...141,733,987
Ensembl chr 4:141,636,583...141,733,987 		JBrowse link
G IL1B interleukin 1 beta ISO RGD PMID:20065029 RGD:4142828 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL33 interleukin 33 ISO mRNA:increased expression:lung: RGD PMID:28401938 RGD:40400699 NCBI chr 9:6,215,149...6,257,983
Ensembl chr 9:6,215,786...6,257,983 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 ISO RGD PMID:20493961 RGD:5131444 NCBI chr16:50,693,606...50,733,075
Ensembl chr16:50,693,588...50,733,077 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase ISO protein:increased expression:lung (mouse) RGD PMID:28663335 RGD:13432209 NCBI chr 6:161,347,417...162,727,766
Ensembl chr 6:161,347,417...162,727,775 		JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 severity ISO mRNA:increased expression:lung
associated with influenza		 RGD PMID:31782850 PMID:31782850 RGD:39131288, RGD:39131288 NCBI chr12:112,418,947...112,509,918
Ensembl chr12:112,418,351...112,509,918 		JBrowse link
G RIPK3 receptor interacting serine/threonine kinase 3 treatment ISO RGD PMID:25445964 RGD:127229910 NCBI chr14:24,336,025...24,339,991
Ensembl chr14:24,336,025...24,340,022 		JBrowse link
G SFTPB surfactant protein B ameliorates IDA RGD PMID:20007532 RGD:151667448 NCBI chr 2:85,657,307...85,668,741
Ensembl chr 2:85,657,314...85,668,741 		JBrowse link
Streptococcus pneumonia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATM ATM serine/threonine kinase exacerbates ISO RGD PMID:27421701 RGD:126779562 NCBI chr11:108,223,067...108,369,102
Ensembl chr11:108,222,823...108,369,102 		JBrowse link
G BTK Bruton tyrosine kinase ISO RGD PMID:30873567 RGD:124715473 NCBI chr  X:101,349,450...101,390,796
Ensembl chr  X:101,349,338...101,390,796 		JBrowse link
G CLEC4M C-type lectin domain family 4 member M severity ISO RGD PMID:16134084 RGD:39938986 NCBI chr19:7,763,243...7,769,605
Ensembl chr19:7,763,210...7,769,605 		JBrowse link
G IDO1 indoleamine 2,3-dioxygenase 1 ISO mRNA:increased expression:lung (mouse) RGD PMID:20385761 RGD:39938865 NCBI chr 8:39,913,891...39,928,790
Ensembl chr 8:39,902,275...39,928,790 		JBrowse link
G IFNG interferon gamma ISO protein:increased expression:lung,natural killer cell (mouse) RGD PMID:21887255 RGD:40818252 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IL6 interleukin 6 ISO protein:increased expression:lung,natural killer cell (mouse) RGD PMID:21887255 RGD:40818252 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G IRAK3 interleukin 1 receptor associated kinase 3 severity ISO RGD PMID:22492852 RGD:35316076 NCBI chr12:66,189,214...66,254,622
Ensembl chr12:66,189,195...66,254,622 		JBrowse link
G ITGB2 integrin subunit beta 2 susceptibility ISO RGD PMID:11390487 RGD:127345090 NCBI chr21:44,885,953...44,928,815
Ensembl chr21:44,885,953...44,931,989 		JBrowse link
G LAMP1 lysosomal associated membrane protein 1 ISO protein:increased expression:lung, natural killer cell (mouse) RGD PMID:21887255 RGD:40818252 NCBI chr13:113,297,239...113,323,672
Ensembl chr13:113,297,239...113,323,672 		JBrowse link
G MARCO macrophage receptor with collagenous structure exacerbates ISO RGD PMID:15263032 RGD:41412189 NCBI chr 2:118,942,194...118,994,660
Ensembl chr 2:118,942,194...118,994,660 		JBrowse link
G NCR1 natural cytotoxicity triggering receptor 1 severity ISO RGD PMID:21887255 RGD:40818252 NCBI chr19:54,898,198...54,938,208
Ensembl chr19:54,906,148...54,916,140 		JBrowse link
G PDCD1 programmed cell death 1 treatment ISO RGD PMID:25624454 RGD:40818422 NCBI chr 2:241,849,884...241,858,894
Ensembl chr 2:241,849,884...241,858,894 		JBrowse link
G PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta treatment ISO associated with immunodeficiency 14 RGD PMID:30093657 RGD:40890269 NCBI chr 1:9,627,258...9,729,114
Ensembl chr 1:9,629,889...9,729,114 		JBrowse link
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma severity ISO RGD PMID:17322108 RGD:38599154 NCBI chr 7:106,865,282...106,908,980
Ensembl chr 7:106,865,278...106,908,980 		JBrowse link
G RIPK3 receptor interacting serine/threonine kinase 3 exacerbates ISO RGD PMID:33625952 RGD:127229925 NCBI chr14:24,336,025...24,339,991
Ensembl chr14:24,336,025...24,340,022 		JBrowse link
G TNF tumor necrosis factor ISO protein:increased expression:lung,natural killer cell (mouse) RGD PMID:21887255 RGD:40818252 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
strongyloidiasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL18 interleukin 18 treatment ISO RGD PMID:16129701 RGD:8655932 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096 		JBrowse link
G IL5 interleukin 5 severity ISO RGD PMID:9824515 RGD:11354934 NCBI chr 5:132,541,445...132,556,815
Ensembl chr 5:132,541,445...132,556,838 		JBrowse link
tonsillitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IGFBP3 insulin like growth factor binding protein 3 treatment IEP RGD PMID:27738609 RGD:12743605 NCBI chr 7:45,912,245...45,921,272
Ensembl chr 7:45,912,245...45,921,874 		JBrowse link
Viral Bronchiolitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM33 ADAM metallopeptidase domain 33 susceptibility IAGP DNA:SNP: :rs2787094 c.2891G>C (human) RGD PMID:19258923 RGD:4142862 NCBI chr20:3,667,975...3,682,010
Ensembl chr20:3,667,965...3,682,246 		JBrowse link
G BCL2 BCL2 apoptosis regulator severity IEP protein:increased expression:natural killer cell, T cell (human) RGD PMID:26541527 RGD:40902860 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BCL2L1 BCL2 like 1 severity IEP protein:increased expression:natural killer cell,t cell (human) RGD PMID:26541527 RGD:40902860 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989 		JBrowse link
G C3 complement C3 resistance IAGP
ISO		 RGD PMID:19258923 PMID:12235218 RGD:4142862, RGD:5129513 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562 		JBrowse link
G CASP1 caspase 1 IEP RGD PMID:15196254 RGD:5130189 NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250 		JBrowse link
G CAT catalase IEP protein:decreased expression:nasal mucus RGD PMID:21471094 RGD:5130770 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 susceptibility IEP
IAGP		 protein:increased secretion:serum (human)
DNA:snp:5' utr:g.-28C>G (human)		 RGD PMID:19005677 PMID:19099677 RGD:4891884, RGD:4891881 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793 		JBrowse link
G CD14 CD14 molecule IAGP DNA:polymorphism:promoter:c.-550C>T (human) RGD PMID:17471431 RGD:4144210 NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,700 		JBrowse link
G CD274 CD274 molecule treatment ISO mRNA:increased expression:lung RGD PMID:22797302 PMID:22797302 RGD:40818270, RGD:40818270 NCBI chr 9:5,450,542...5,470,554
Ensembl chr 9:5,450,503...5,470,566 		JBrowse link
G CSF2 colony stimulating factor 2 IEP protein:increased expression:nasal mucus RGD PMID:20088864 RGD:4143440 NCBI chr 5:132,073,789...132,076,170
Ensembl chr 5:132,073,789...132,076,170 		JBrowse link
G CX3CR1 C-X3-C motif chemokine receptor 1 IEP
IAGP		 DNA:SNP: :p.T280M (human) RGD PMID:18257903 PMID:16645504 RGD:4891891, RGD:4891905 NCBI chr 3:39,263,494...39,292,966
Ensembl chr 3:39,263,495...39,281,735 		JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 ISO
IEP		 mRNA:increased expression:lung
protein:increased expression:plasma		 RGD PMID:12909590 PMID:20561238 RGD:2311388, RGD:5135493 NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497 		JBrowse link
G CXCR3 C-X-C motif chemokine receptor 3 IEP RGD PMID:20561238 RGD:5135493 NCBI chr  X:71,615,919...71,618,511
Ensembl chr  X:71,615,916...71,618,511 		JBrowse link
G FAS Fas cell surface death receptor severity HEP mRNA:increased expression:peripheral blood mononuclear cell (human) RGD PMID:26541527 RGD:40902860 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605 		JBrowse link
G FLT3 fms related receptor tyrosine kinase 3 severity HEP mRNA:increased expression:peripheral blood mononuclear cell (human) RGD PMID:26541527 RGD:40902860 NCBI chr13:28,003,274...28,100,576
Ensembl chr13:28,003,274...28,100,592 		JBrowse link
G GAPDH glyceraldehyde-3-phosphate dehydrogenase severity HEP mRNA:increased expression:peripheral blood mononuclear cell (human) RGD PMID:26541527 RGD:40902860 NCBI chr12:6,534,517...6,538,371
Ensembl chr12:6,534,512...6,538,374 		JBrowse link
G IFNL1 interferon lambda 1 exacerbates IEP associated with respiratory syncytial virus infectious disease;mRNA:increased expression:mucosa of nasopharynx (human) RGD PMID:24389019 RGD:126848743 NCBI chr19:39,296,407...39,298,673
Ensembl chr19:39,296,407...39,298,673 		JBrowse link
G IL15 interleukin 15 severity IEP mRNA,protein:increased expression:peripheral blood mononuclear cell,serum,dendritic cell (human) RGD PMID:26541527 RGD:40902860 NCBI chr 4:141,636,583...141,733,987
Ensembl chr 4:141,636,583...141,733,987 		JBrowse link
G IL17A interleukin 17A susceptibility IAGP DNA:SNP: :rs7747909(human) RGD PMID:17703412 RGD:4889847 NCBI chr 6:52,186,375...52,190,638
Ensembl chr 6:52,186,375...52,190,638 		JBrowse link
G IL1RN interleukin 1 receptor antagonist susceptibility IAGP DNA:SNP: :c.390T>C (rs315952) (human) RGD PMID:19258923 RGD:4142862 NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016 		JBrowse link
G IL33 interleukin 33 IEP protein:increased expression:nasal mucus RGD PMID:28471975 RGD:38596342 NCBI chr 9:6,215,149...6,257,983
Ensembl chr 9:6,215,786...6,257,983 		JBrowse link
G IL4R interleukin 4 receptor susceptibility ISO
IAGP		 DNA:SNPs: :rs1805011,rs2057768 (human)
associated with respiratory syncystial virus infection; DNA:polymorphism:cds:p. Q551R (human)		 RGD PMID:20404812 PMID:17703412 PMID:12508140 RGD:4889996, RGD:4889847, RGD:4890022 NCBI chr16:27,313,756...27,364,778
Ensembl chr16:27,313,668...27,364,778 		JBrowse link
G IL6 interleukin 6 IEP mRNA, protein:increased expression:respiratory system fluid/secretion RGD PMID:14738241 RGD:5128668 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G IL9 interleukin 9 IEP RGD PMID:15051283 RGD:5128692 NCBI chr 5:135,892,246...135,895,841
Ensembl chr 5:135,892,246...135,895,841 		JBrowse link
G JAK3 Janus kinase 3 severity HEP mRNA:increased expression:peripheral blood mononuclear cell (human) RGD PMID:26541527 RGD:40902860 NCBI chr19:17,824,782...17,847,982
Ensembl chr19:17,824,780...17,848,071 		JBrowse link
G KLRK1 killer cell lectin like receptor K1 susceptibility IAGP DNA:SNP,haplotypes:3'utr: (rs10772271) (human) RGD PMID:29967528 RGD:39128159 NCBI chr12:10,372,353...10,390,041
Ensembl chr12:10,372,353...10,391,874 		JBrowse link
G MPO myeloperoxidase IEP RGD PMID:7841728 RGD:5130995 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935 		JBrowse link
G MUC1 mucin 1, cell surface associated severity IEP protein:increased expression:serum RGD PMID:19856476 RGD:5131164 NCBI chr 1:155,185,824...155,192,915
Ensembl chr 1:155,185,824...155,192,916 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 severity HEP mRNA:increased expression:peripheral blood mononuclear cell (human) RGD PMID:26541527 RGD:40902860 NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302 		JBrowse link
G NFKBIA NFKB inhibitor alpha susceptibility IAGP associated with respiratory syncytial virus infectious disease;DNA:SNP:promoter: (rs2233406) (human) RGD PMID:23487427 RGD:40902982 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NOS2 nitric oxide synthase 2 susceptibility IAGP DNA:SNP: :rs1060826(human) RGD PMID:17703412 RGD:4889847 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G PDCD1 programmed cell death 1 ISO protein:increased expression:CD8 T cell RGD PMID:22797302 RGD:40818270 NCBI chr 2:241,849,884...241,858,894
Ensembl chr 2:241,849,884...241,858,894 		JBrowse link
G POSTN periostin IEP mRNA,protein:increased expression:nasal mucus RGD PMID:28471975 RGD:38596342 NCBI chr13:37,562,585...37,598,768
Ensembl chr13:37,562,583...37,598,844 		JBrowse link
G STAT5A signal transducer and activator of transcription 5A severity HEP mRNA:increased expression:peripheral blood mononuclear cell (human) RGD PMID:26541527 RGD:40902860 NCBI chr17:42,287,439...42,311,943
Ensembl chr17:42,287,547...42,311,943 		JBrowse link
G TLR4 toll like receptor 4 IEP protein:decreased expression:neutrophil
protein:increased expression:monocyte		 RGD PMID:19497921 PMID:14738455 RGD:4144183, RGD:4144819 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G TLR5 toll like receptor 5 susceptibility IAGP DNA:snp:cds:p.F616L rs5744174 (human) RGD PMID:19258923 RGD:4142862 NCBI chr 1:223,109,404...223,143,248
Ensembl chr 1:223,109,404...223,143,248 		JBrowse link
G TNF tumor necrosis factor susceptibility IAGP
IEP		 DNA:SNP: :rs1799724(human)
protein:increased expression:nasal lavage fluid
DNA:polymorphism:promoter: c. -308A>G (human)		 RGD PMID:17703412 PMID:20088864 PMID:19849941 RGD:4889847, RGD:4143440, RGD:4143441 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFRSF10A TNF receptor superfamily member 10a severity HEP mRNA:increased expression:peripheral blood mononuclear cell (human) RGD PMID:26541527 RGD:40902860 NCBI chr 8:23,190,452...23,225,102
Ensembl chr 8:23,190,452...23,225,102 		JBrowse link
G TSLP thymic stromal lymphopoietin severity IEP mRNA, protein:increased expression:nasal mucus (human) RGD PMID:28471975 RGD:38596342 NCBI chr 5:111,070,062...111,078,026
Ensembl chr 5:111,070,062...111,078,026 		JBrowse link
G VDR vitamin D receptor susceptibility IAGP DNA:SNP: :rs10735810 (human)
DNA:SNP (human)		 RGD PMID:17703412 PMID:18266602 RGD:4889847, RGD:4889843 NCBI chr12:47,841,537...47,904,994
Ensembl chr12:47,841,537...47,943,048 		JBrowse link
viral pneumonia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme EXP CTD Direct Evidence: marker/mechanism CTD PMID:15381116 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380 		JBrowse link
G CCL11 C-C motif chemokine ligand 11 IEP RGD PMID:20644177 RGD:4140459 NCBI chr17:34,285,742...34,288,334
Ensembl chr17:34,285,742...34,288,334 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 ISO RGD PMID:19617401 RGD:4891451 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CCL3 C-C motif chemokine ligand 3 HEP mRNA:increased expression:bronchoalveolar lavage (human) RGD PMID:32407669 RGD:30296672 NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169 		JBrowse link
G CCL4 C-C motif chemokine ligand 4 IEP
HEP		 mRNA:increased expression:bronchoalveolar lavage (human) RGD PMID:20957032 PMID:32407669 RGD:5130904, RGD:30296672 NCBI chr17:36,103,827...36,105,614
Ensembl chr17:36,103,827...36,105,621 		JBrowse link
G CCR1 C-C motif chemokine receptor 1 ISO RGD PMID:15254170 RGD:5688163 NCBI chr 3:46,201,711...46,208,313
Ensembl chr 3:46,201,711...46,208,313 		JBrowse link
G CD68 CD68 molecule ISO mRNA:increased expression:lung,trachea (mouse) RGD PMID:12581500 RGD:40925942 NCBI chr17:7,579,638...7,582,111
Ensembl chr17:7,579,491...7,582,111 		JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 ISO protein:increased expression:respiratory system fluid/secretion RGD PMID:19671179 RGD:5134975 NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308 		JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 ISO RGD PMID:17655904 RGD:5135437 NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497 		JBrowse link
G CXCL16 C-X-C motif chemokine ligand 16 HEP mRNA:decreased expression:bronchoalveolar lavage (human) RGD PMID:32407669 RGD:30296672 NCBI chr17:4,733,533...4,739,928
Ensembl chr17:4,733,533...4,739,928 		JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 ISO protein:increased expression:respiratory system fluid/secretion RGD PMID:19671179 RGD:5134975 NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 HEP mRNA:increased expression:bronchoalveolar lavage (human) RGD PMID:32407669 RGD:30296672 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CXCL9 C-X-C motif chemokine ligand 9 ISO RGD PMID:17655904 RGD:5135437 NCBI chr 4:76,001,275...76,007,509
Ensembl chr 4:76,001,275...76,007,509 		JBrowse link
G FGF10 fibroblast growth factor 10 treatment ISO protein:increased expression:epithelial stem/progenitor cells (mouse) RGD PMID:27322618 PMID:27322618 RGD:127284849, RGD:127284849 NCBI chr 5:44,300,247...44,389,420
Ensembl chr 5:44,300,247...44,389,706 		JBrowse link
G FGFR2 fibroblast growth factor receptor 2 ISO protein:increased expression:epithelial stem/progenitor cells (mouse) RGD PMID:27322618 RGD:127284849 NCBI chr10:121,478,330...121,598,458
Ensembl chr10:121,478,332...121,598,458 		JBrowse link
G HMOX1 heme oxygenase 1 ISO mRNA:increased expression:lung RGD PMID:8843786 RGD:4145417 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G IFNAR1 interferon alpha and beta receptor subunit 1 disease_progression ISO H1N1 virus susceptibility RGD PMID:21383977 PMID:21383977 RGD:5490272, RGD:5490272 NCBI chr21:33,324,395...33,359,864
Ensembl chr21:33,324,387...33,359,864 		JBrowse link
G IL10 interleukin 10 treatment ISO RGD PMID:25219125 RGD:10450576 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL15 interleukin 15 ISO RGD PMID:20335267 RGD:4892670 NCBI chr 4:141,636,583...141,733,987
Ensembl chr 4:141,636,583...141,733,987 		JBrowse link
G IL17RA interleukin 17 receptor A HEP mRNA:decreased expression:bronchoalveolar lavage (human) RGD PMID:32407669 RGD:30296672 NCBI chr22:17,085,000...17,115,693
Ensembl chr22:17,084,954...17,115,693 		JBrowse link
G IL1B interleukin 1 beta HEP mRNA:increased expression:bronchoalveolar lavage (human) RGD PMID:32407669 RGD:30296672 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL1RN interleukin 1 receptor antagonist HEP mRNA:increased expression:bronchoalveolar lavage (human) RGD PMID:32407669 RGD:30296672 NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016 		JBrowse link
G IL4R interleukin 4 receptor HEP mRNA:decreased expression:bronchoalveolar lavage (human) RGD PMID:32407669 RGD:30296672 NCBI chr16:27,313,756...27,364,778
Ensembl chr16:27,313,668...27,364,778 		JBrowse link
G MIF macrophage migration inhibitory factor ISO RGD PMID:19941385 RGD:4891005 NCBI chr22:23,894,383...23,895,223
Ensembl chr22:23,894,383...23,895,227 		JBrowse link
G TLR9 toll like receptor 9 IAGP DNA:SNP:promoter:g.-1237T>C rs5743836 (human) RGD PMID:19539691 RGD:5130766 NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,225,645 		JBrowse link
G TNF tumor necrosis factor treatment ISO RGD PMID:25219125 RGD:10450576 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
X-linked retinitis pigmentosa and sinorespiratory infections term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RPGR retinitis pigmentosa GTPase regulator IAGP
EXP		 ClinVar Annotator: match by term: Retinitis pigmentosa, X-linked, and sinorespiratory infections, with or without deafness
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: RETINITIS PIGMENTOSA, SINORESPIRATORY INFECTIONS, AND DEAFNESS		 ClinVar
CTD
OMIM		 PMID:1733835 PMID:8673101 PMID:10094550 PMID:14627685 PMID:16055928 More... NCBI chr  X:38,269,163...38,327,509
Ensembl chr  X:38,269,163...38,327,544 		JBrowse link
Young Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PGK1 phosphoglycerate kinase 1 IAGP ClinVar Annotator: match by term: Male infertility due to obstructive azoospermia ClinVar NCBI chr  X:78,104,248...78,129,295
Ensembl chr  X:77,910,739...78,129,295 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 41189
    disease of anatomical entity 32344
      respiratory system disease 4136
        Respiratory Tract Infections 571
          Bacterial Lung Diseases + 150
          Bovine Respiratory Disease Complex + 0
          Fungal Lung Diseases + 55
          Human Influenza + 123
          Parasitic Lung Diseases + 2
          RESPIRATORY INFECTIONS, RECURRENT, AND FAILURE TO THRIVE WITH OR WITHOUT DIARRHEA 1
          Recurrent Respiratory Papillomatosis 11
          Supraglottitis + 0
          X-linked retinitis pigmentosa and sinorespiratory infections 1
          Young Syndrome 1
          bronchitis + 92
          common cold 18
          laryngeal tuberculosis 0
          laryngitis + 0
          legionellosis + 16
          lung abscess 0
          pertussis + 0
          pharyngitis + 2
          pleural empyema + 3
          pleural tuberculosis + 13
          pleurisy + 36
          pneumonia + 303
          pulmonary tuberculosis + 92
          rhinitis + 154
          rhinoscleroma 2
          severe acute respiratory syndrome 91
          sinusitis + 45
          tracheitis 0
paths to the root