RGD DISEASE ONTOLOGY - ANNOTATIONS
RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term: Somatosensory Disorders
Accession: DOID:9008625
browse the term
Definition: Disorders of sensory information received from superficial and deep regions of the body. The somatosensory system conveys neural impulses which pertain to proprioception, tactile sensation, thermal sensation, pressure sensation, and pain. PERIPHERAL NERVOUS SYSTEM DISEASES; SPINAL CORD DISEASES; and BRAIN DISEASES may be associated with impaired or abnormal somatic sensation.
Synonyms: exact_synonym: Light Touch Sensation Impairment; Pain Sensation Diminished; Pain Sensation Diminisheds; Pinprick Sensation Diminished; Pinprick Sensation Diminisheds; Position Sense Disorder; Position Sense Disorders; Proprioceptive Disorder; Proprioceptive Disorders; Somatic Sensation Disorder; Somatic Sensation Disorders; Somatosensory Disorder; Thermal Sensation Disorder; Thermal Sensation Disorders
primary_id: MESH:D020886
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Csf3
colony stimulating factor 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:7543699
NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
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Ttpa
alpha tocopherol transfer protein
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:10896705
NCBI chr 5:33,497,537...33,518,936
Ensembl chr 5:33,497,137...33,518,073
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Acod1
aconitate decarboxylase 1
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:79,871,819...79,881,101
Ensembl chr15:79,871,827...79,880,529
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Alg11
ALG11, alpha-1,2-mannosyltransferase
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr16:69,940,540...69,951,617
Ensembl chr16:69,944,349...69,951,601
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Arl11
ADP-ribosylation factor like GTPase 11
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:35,483,330...35,485,579
Ensembl chr15:35,480,018...35,496,596
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Atp7b
ATPase copper transporting beta
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636
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Bora
bora, aurora kinase A activator
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:75,797,624...75,835,599
Ensembl chr15:75,797,891...75,821,322
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C15h13orf42
similar to human chromosome 13 open reading frame 42
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:36,674,840...36,701,304
Ensembl chr15:36,677,527...36,701,211
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Cab39l
calcium binding protein 39-like
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:33,606,588...33,710,518
Ensembl chr15:33,606,694...33,743,545
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Ccdc70
coiled-coil domain containing 70
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr16:70,037,309...70,042,401
Ensembl chr16:70,037,309...70,042,339
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Cdadc1
cytidine and dCMP deaminase domain containing 1
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:33,726,590...33,755,611
Ensembl chr15:33,723,435...33,755,576
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Ckap2
cytoskeleton associated protein 2
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr16:69,839,668...69,864,852
Ensembl chr16:69,839,630...69,864,913
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Cln5
CLN5, intracellular trafficking protein
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:79,893,573...79,903,438
Ensembl chr15:79,893,548...79,903,438
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Cnmd
chondromodulin
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:55,041,548...55,066,297
Ensembl chr15:55,041,561...55,066,297
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Commd6
COMM domain containing 6
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:78,467,333...78,474,382
Ensembl chr15:78,467,804...78,474,382
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Cysltr2
cysteinyl leukotriene receptor 2
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:48,189,476...48,228,750
Ensembl chr15:48,189,073...48,304,136
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Dach1
dachshund family transcription factor 1
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:74,528,122...74,909,811
Ensembl chr15:74,529,208...74,909,922
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Diaph3
diaphanous-related formin 3
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:62,543,375...63,013,060
Ensembl chr15:62,543,375...63,012,975
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Dis3
DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:75,820,040...75,850,450
Ensembl chr15:75,823,436...75,850,642
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Dleu7
deleted in lymphocytic leukemia, 7
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:36,479,533...36,495,730
Ensembl chr15:36,479,534...36,495,697
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Ebpl
EBP like
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:35,508,074...35,531,472
Ensembl chr15:35,508,074...35,531,472
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Ednrb
endothelin receptor type B
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115
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Fam124a
family with sequence similarity 124 member A
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:36,799,836...36,855,062
Ensembl chr15:36,799,877...36,853,683
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Fbxl3
F-box and leucine-rich repeat protein 3
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:79,906,795...79,926,678
Ensembl chr15:79,906,795...79,927,867
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Fndc3a
fibronectin type III domain containing 3a
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:47,689,909...47,867,354
Ensembl chr15:47,689,919...47,866,784
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Ints6
integrator complex subunit 6
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:36,908,966...37,048,043
Ensembl chr15:36,933,724...37,021,527
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Itm2b
integral membrane protein 2B
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:48,545,998...48,568,904
Ensembl chr15:48,546,001...48,568,917
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Kcnrg
potassium channel regulator
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:35,774,456...35,779,409
Ensembl chr15:35,774,326...35,779,415
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Kctd12
potassium channel tetramerization domain containing 12
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:79,800,078...79,806,017
Ensembl chr15:79,801,191...79,806,282
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Klf12
KLF transcription factor 12
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:76,628,778...77,062,000
Ensembl chr15:76,637,654...77,062,056
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Klf5
KLF transcription factor 5
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:76,060,320...76,079,445
Ensembl chr15:76,064,258...76,079,445
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Klhl1
kelch-like family member 1
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:72,698,191...73,142,726
Ensembl chr15:72,699,094...73,142,594
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Kpna3
karyopherin subunit alpha 3
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:35,536,310...35,610,066
Ensembl chr15:35,536,316...35,610,419
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Lmo7
LIM domain 7
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:78,566,999...78,769,833
Ensembl chr15:78,567,023...78,769,783
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Lpar6
lysophosphatidic acid receptor 6
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:48,416,548...48,418,357
Ensembl chr15:48,416,544...48,422,331
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Med4
mediator complex subunit 4
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:48,696,542...48,706,818
Ensembl chr15:48,696,511...48,706,820
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Mycbp2
MYC binding protein 2
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:79,937,354...80,175,432
Ensembl chr15:79,937,354...80,175,498
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Mzt1
mitotic spindle organizing protein 1
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:75,787,281...75,797,589
Ensembl chr15:75,786,994...75,797,589
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Ndfip2
Nedd4 family interacting protein 2
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:82,032,366...82,087,043
Ensembl chr15:82,032,366...82,086,317
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Nek3
NIMA-related kinase 3
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr16:69,867,020...69,892,477
Ensembl chr16:69,867,047...69,892,508
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Nek5
NIMA-related kinase 5
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr16:69,895,414...69,938,668
Ensembl chr16:69,895,422...69,939,429
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Nudt15
nudix hydrolase 15
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:48,707,776...48,713,847
Ensembl chr15:48,709,700...48,747,363
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Obi1
ORC ubiquitin ligase 1
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:81,269,413...81,308,734
Ensembl chr15:81,269,416...81,308,734
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Olfm4
olfactomedin 4
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:55,385,100...55,429,687
Ensembl chr15:55,407,148...55,429,681
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Pcdh17
protocadherin 17
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:60,222,088...60,316,172
Ensembl chr15:60,222,004...60,313,999
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Pcdh20
protocadherin 20
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:64,425,534...64,431,790
Ensembl chr15:64,425,534...64,431,790
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Pcdh8
protocadherin 8
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:55,198,470...55,203,039
Ensembl chr15:55,198,459...55,205,872
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Pcdh9
protocadherin 9
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:69,340,108...70,237,531
Ensembl chr15:69,340,645...70,237,538
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Phf11
PHD finger protein 11
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:33,390,290...33,414,647
Ensembl chr15:33,390,292...33,413,009
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Pibf1
progesterone immunomodulatory binding factor 1
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:75,850,389...76,019,711
Ensembl chr15:75,850,624...76,019,712
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Pou4f1
POU class 4 homeobox 1
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:81,253,714...81,260,057
Ensembl chr15:81,257,781...81,259,728
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Prr20e
proline rich 20E
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr 4:121,566,632...121,574,734
Ensembl chr 4:121,571,797...121,573,140
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Rb1
RB transcriptional corepressor 1
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
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Rbm26
RNA binding motif protein 26
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:81,884,783...81,964,245
Ensembl chr15:81,887,219...81,964,118
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Rcbtb1
RCC1 and BTB domain containing protein 1
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:33,319,586...33,362,421
Ensembl chr15:33,319,586...33,365,302
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Rcbtb2
RCC1 and BTB domain containing protein 2
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:48,319,809...48,364,441
Ensembl chr15:48,323,866...48,383,750
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Rnaseh2b
ribonuclease H2, subunit B
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:36,541,200...36,592,016
Ensembl chr15:36,541,218...36,584,118
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Scel
sciellin
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:80,339,661...80,456,546
Ensembl chr15:80,339,951...80,456,372
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Serpine3
serpin family E member 3
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:36,908,816...36,931,825
Ensembl chr15:36,907,131...36,933,150
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Setdb2
SET domain bifurcated histone lysine methyltransferase 2
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:33,553,657...33,606,586
Ensembl chr15:33,453,952...33,606,470
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Slain1
SLAIN motif family, member 1
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:80,482,818...80,542,461
Ensembl chr15:80,482,367...80,542,350
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Slitrk1
SLIT and NTRK-like family, member 1
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:85,723,252...85,727,290
Ensembl chr15:85,724,475...85,727,509
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Slitrk6
SLIT and NTRK-like family, member 6
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:87,563,506...87,570,125
Ensembl chr15:87,563,322...87,570,393
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Spry2
sprouty RTK signaling antagonist 2
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:82,692,291...82,697,408
Ensembl chr15:82,692,143...82,698,009
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Spryd7
SPRY domain containing 7
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:35,707,185...35,727,704
Ensembl chr15:35,707,060...35,727,509
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Sucla2
succinate-CoA ligase ADP-forming subunit beta
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:48,752,356...48,805,495
Ensembl chr15:48,752,312...48,805,138
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Sugt1
SGT1 homolog, MIS12 kinetochore complex assembly cochaperone
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:54,991,419...55,032,244
Ensembl chr15:54,990,672...55,069,150
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Tbc1d4
TBC1 domain family, member 4
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:78,256,030...78,434,168
Ensembl chr15:78,257,121...78,434,265
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Tdrd3
tudor domain containing 3
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:63,340,531...63,497,208
Ensembl chr15:63,341,235...63,476,110
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Thsd1
thrombospondin type 1 domain containing 1
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr16:69,771,408...69,804,844
Ensembl chr16:69,771,408...69,801,504
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Trim13
tripartite motif-containing 13
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:35,733,548...35,772,676
Ensembl chr15:35,734,107...35,772,677
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Uchl3
ubiquitin C-terminal hydrolase L3
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:78,485,304...78,527,355
Ensembl chr15:78,485,315...78,527,355 Ensembl chr 3:78,485,315...78,527,355
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Vps36
vacuolar protein sorting 36 homolog
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr16:69,810,404...69,834,789
Ensembl chr16:69,808,193...69,834,810
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Wdfy2
WD repeat and FYVE domain containing 2
ISO
ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome
ClinVar
NCBI chr15:37,083,842...37,209,559
Ensembl chr15:37,042,987...37,209,304
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Adam3a
ADAM metallopeptidase domain 3A
ISO
DNA, mRNA:amplification, increase expression
RGD
PMID:25491297
RGD:13831354
NCBI chr16:67,299,949...67,349,970
Ensembl chr16:67,299,949...67,349,968
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Piezo2
piezo-type mechanosensitive ion channel component 2
ISO
CTD Direct Evidence: marker/mechanism ClinVar Annotator: match by term: Arthrogryposis, distal, with impaired proprioception and touch
OMIM CTD ClinVar
PMID:8423615 PMID:11152147 PMID:24726473 PMID:25741868 PMID:27607563 PMID:27653382 PMID:27714920 PMID:27843126 PMID:27974811 PMID:28492532 PMID:31680123 More...
NCBI chr18:56,468,449...56,844,984
Ensembl chr18:56,469,680...56,844,216
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Stk11
serine/threonine kinase 11
ISO
ClinVar Annotator: match by term: Arthrogryposis, distal, with impaired proprioception and touch
ClinVar
PMID:25741868 PMID:28492532
NCBI chr 7:9,574,553...9,591,315
Ensembl chr 7:9,575,269...9,591,315
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Rb1
RB transcriptional corepressor 1
ISO
DNA:mutations:promoter, intron, exon:multiple ClinVar Annotator: match by term: Hereditary retinoblastoma
ClinVar RGD
PMID:7881418 PMID:8346255 PMID:8605116 PMID:8651278 PMID:9536098 PMID:9671401 PMID:10486322 PMID:10617920 PMID:10671068 PMID:11668642 PMID:12541220 PMID:15884040 PMID:16269091 PMID:17576681 PMID:18449911 PMID:18677112 PMID:22084214 PMID:25741868 PMID:25754945 PMID:28492532 PMID:17096365 More...
RGD:8547984
NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
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Abat
4-aminobutyrate aminotransferase
treatment
IMP
RGD
PMID:24890317
RGD:9588557
NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835
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Adk
adenosine kinase
IMP
associated with diabetic neuropathies;
RGD
PMID:11423084 PMID:9932716
RGD:6482662 , RGD:6482666
NCBI chr15:2,863,241...3,246,453
Ensembl chr15:2,863,244...3,246,510
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Adm
adrenomedullin
IDA ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:17043245 PMID:17043245
RGD:1625316
NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
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Adora1
adenosine A1 receptor
IDA
associated with Spinal Cord Injuries
RGD
PMID:20065990
RGD:5129094
NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801
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Adra1a
adrenoceptor alpha 1A
IEP
associated with Diabetes Mellitus, Experimental; mRNA:increased expression:dorsal root ganglion
RGD
PMID:10841349
RGD:5688377
NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500
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Adra2a
adrenoceptor alpha 2A
IMP
RGD
PMID:17959985
RGD:6480488
NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365
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Adra2c
adrenoceptor alpha 2C
IMP
RGD
PMID:20007733
RGD:6893568
NCBI chr14:75,470,884...75,472,846
Ensembl chr14:75,471,143...75,472,846
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Adrb1
adrenoceptor beta 1
IMP
RGD
PMID:19283893
RGD:5129125
NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259
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Ager
advanced glycosylation end product-specific receptor
treatment
IMP ISO IEP
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:25014009 PMID:25014009 PMID:24077211
RGD:8695980 , RGD:7364865
NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
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Agt
angiotensinogen
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:9613798
NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
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Aif1
allograft inflammatory factor 1
IEP ISO
associated with Alcohol-Induced Disorders, Nervous System; protein:increased expression:spinal cord (rat) CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:27093858 PMID:17284346
RGD:2313035
NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668
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Akr1b1
aldo-keto reductase family 1 member B1
IDA
associated with Hyperglycemia
RGD
PMID:12505670
RGD:1626082
NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
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Alox12
arachidonate 12-lipoxygenase, 12S type
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12582831
NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542
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Alox5
arachidonate 5-lipoxygenase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12582831
NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
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Ano3
anoctamin 3
IMP
RGD
PMID:23872594
RGD:9681745
NCBI chr 3:97,235,671...97,550,090
Ensembl chr 3:97,238,354...97,550,154
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Anxa1
annexin A1
IMP IEP
protein:increased expression:dorsal root ganglion
RGD
PMID:9222544 PMID:21990306
RGD:2306950 , RGD:7421656
NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
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Aqp4
aquaporin 4
IEP
associated with Spinal Cord Injuries;mRNA,protein:increased expression:brain,spinal cord:
RGD
PMID:16219025
RGD:8695957
NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856
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Avp
arginine vasopressin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:9613798
NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425
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Bace1
beta-secretase 1
IMP
RGD
PMID:28012171
RGD:13782150
NCBI chr 8:46,142,060...46,166,268
Ensembl chr 8:46,142,116...46,165,876
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Bdkrb1
bradykinin receptor B1
IDA ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:17989505 PMID:19300402 PMID:19815945 PMID:12927641 PMID:12637034
RGD:1579989 , RGD:7241581
NCBI chr 6:124,510,827...124,514,475
Ensembl chr 6:124,510,870...124,513,747
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Bdkrb2
bradykinin receptor B2
IMP ISO
CTD Direct Evidence: marker/mechanism associated with Diabetic Neuropathy
CTD RGD
PMID:17989505 PMID:19300402 PMID:19815945 PMID:10188975 PMID:19300402
RGD:4891040 , RGD:2313332
NCBI chr 6:124,472,317...124,502,497
Ensembl chr 6:124,472,566...124,502,497
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Bdnf
brain-derived neurotrophic factor
IMP IEP IDA ISO
associated with Peripheral Nerve Injuries; associated with inflammation;protein:increased expression:dorsal root ganglion: associated with Sciatic Neuropathy; associated with Pancreatitis, Chronic;
RGD
PMID:11425916 PMID:21958434 PMID:10779676 PMID:12435470 PMID:21864655 PMID:21499209 PMID:12470870 More...
RGD:8657088 , RGD:8657122 , RGD:8657114 , RGD:8657101 , RGD:8657099 , RGD:8657093 , RGD:8657091
NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
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Becn1
beclin 1
IEP
RGD
PMID:23665054
RGD:11560531
NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
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C3
complement C3
IEP
associated with Sciatic Neuropathy;mRNA, protein:increased expression:spinal cord
RGD
PMID:23588254
RGD:7401259
NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
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Cacna1b
calcium voltage-gated channel subunit alpha1 B
IDA
RGD
PMID:17567797
RGD:1626313
NCBI chr 3:7,380,892...7,546,104
Ensembl chr 3:7,380,922...7,546,091
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Cacna1h
calcium voltage-gated channel subunit alpha1 H
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19577366 PMID:30552955 PMID:34286406
NCBI chr10:14,390,104...14,448,204
Ensembl chr10:14,390,113...14,448,376
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Cacna1i
calcium voltage-gated channel subunit alpha1 I
IMP
RGD
PMID:17112407
RGD:15003199
NCBI chr 7:111,835,996...111,947,418
Ensembl chr 7:111,836,012...111,944,688
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Cacna2d1
calcium voltage-gated channel auxiliary subunit alpha2delta 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:11245671 PMID:17881535 PMID:24133248
NCBI chr 4:18,950,611...19,374,969
Ensembl chr 4:18,951,002...19,374,969
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Calca
calcitonin-related polypeptide alpha
IEP ISO
associated with inflammation;protein:increased expression:dorsal root ganglion: CTD Direct Evidence: marker/mechanism|therapeutic
CTD RGD
PMID:12787826 PMID:12855330 PMID:15265675 PMID:27093858 PMID:21958434
RGD:8657122
NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
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Camk2a
calcium/calmodulin-dependent protein kinase II alpha
ISO IMP
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:20053885 PMID:18042863
RGD:7240711
NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994
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Capn2
calpain 2
treatment
IMP
associated with Peripheral Nerve Injuries
RGD
PMID:25150005
RGD:13792585
NCBI chr13:94,150,244...94,200,969
Ensembl chr13:94,150,240...94,200,969
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Cartpt
CART prepropeptide
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:21167239
NCBI chr 2:31,255,098...31,257,452
Ensembl chr 2:31,255,098...31,290,713
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Cat
catalase
treatment
IEP IMP
RGD
PMID:23952340 PMID:23658840
RGD:9479063 , RGD:9479069
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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Cck
cholecystokinin
IDA
RGD
PMID:15647484
RGD:1626108
NCBI chr 8:121,153,499...121,160,194
Ensembl chr 8:121,153,500...121,160,084
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Cckbr
cholecystokinin B receptor
IMP ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:11880531 PMID:15647484
RGD:1626108
NCBI chr 1:159,771,733...159,781,738
Ensembl chr 1:159,771,733...159,814,881
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Ccl2
C-C motif chemokine ligand 2
IDA ISO IEP IMP
CTD Direct Evidence: marker/mechanism protein:increased expression:dorsal root ganglion, spinal cord (rat)
CTD RGD
PMID:17881535 PMID:18419759 PMID:21712071 PMID:20737477 PMID:22531750
RGD:2307043 , RGD:8548873 , RGD:8548848 , RGD:8548845
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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Ccl5
C-C motif chemokine ligand 5
IEP IDA
mRNA:increased expression:dorsal root ganglion (rat)
RGD
PMID:18076762 PMID:18656466
RGD:4890034 , RGD:2303121
NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
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Ccr2
C-C motif chemokine receptor 2
IMP ISO IEP
associated with Intervertebral disc disease; associated with Demyelinating Diseases; associated with Sciatic Neuropathy; protein:increased expression:dorsal horn of spinal cord: associated with Bone Neoplasms;protein:increased expression:spinal cord:
RGD
PMID:18419759 PMID:24462503 PMID:18076762 PMID:24907405 PMID:22721162 PMID:23511129 More...
RGD:2307043 , RGD:8661788 , RGD:4890034 , RGD:8661781 , RGD:8548831 , RGD:8661772
NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
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Ccr5
C-C motif chemokine receptor 5
IEP ISO IMP
mRNA:increased expression:dorsal root ganglion (rat) associated with Spinal Cord Injuries
RGD
PMID:18076762 PMID:22033364 PMID:23147416 PMID:24589480
RGD:4890034 , RGD:8551820 , RGD:8551809 , RGD:8551795
NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260
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Cfl1
cofilin 1
IEP
protein:increased phosphorylation:dorsal root ganglion (rat)
RGD
PMID:24962708
RGD:11570412
NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587
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Chrna5
cholinergic receptor nicotinic alpha 5 subunit
ameliorates
IMP
RGD
PMID:15652389
RGD:150530460
NCBI chr 8:55,369,794...55,398,526
Ensembl chr 8:55,369,794...55,398,146
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Chrna7
cholinergic receptor nicotinic alpha 7 subunit
ameliorates
IDA
associated with sciatic neuropathy;
RGD
PMID:20619541
RGD:151708701
NCBI chr 1:116,711,559...116,837,269
Ensembl chr 1:116,714,711...116,837,240
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Cnr1
cannabinoid receptor 1
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:17572696
NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
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Cnr2
cannabinoid receptor 2
ISO
CTD Direct Evidence: marker/mechanism|therapeutic
CTD
PMID:17572696 PMID:18664590
NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548
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Comt
catechol-O-methyltransferase
ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:28195063 PMID:20726980
RGD:8662326
NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
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Crcp
CGRP receptor component
IEP
RGD
PMID:12895509
RGD:727768
NCBI chr12:26,623,968...26,659,756
Ensembl chr12:26,623,976...26,768,225
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Crhr1
corticotropin releasing hormone receptor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28434951
NCBI chr10:89,040,186...89,083,481
Ensembl chr10:89,040,203...89,083,481
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Csf3
colony stimulating factor 3
treatment
ISO
associated with Sciatic Neuropathy;
RGD
PMID:24253780
RGD:11039470
NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
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Csk
C-terminal Src kinase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16769263
NCBI chr 8:58,029,748...58,048,742
Ensembl chr 8:58,029,749...58,048,292
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Ctss
cathepsin S
IMP ISO
associated with Arthritis, Experimental associated with Colitis
RGD
PMID:22213084 PMID:21802389
RGD:5686870 , RGD:5686873
NCBI chr 2:183,086,437...183,114,483
Ensembl chr 2:183,086,437...183,114,483
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Cx3cl1
C-X3-C motif chemokine ligand 1
treatment
IDA IEP
associated with Arthritis, Experimental
RGD
PMID:19249394 PMID:22647647
RGD:2304251 , RGD:9491779
NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833
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Cx3cr1
C-X3-C motif chemokine receptor 1
ISO IEP IMP
associated with Arthritis, Experimental;protein:increased expression:lumbar spinal cord associated with Inflammation associated with Sciatic Neuropathy associated with Bone Neoplasms
RGD
PMID:20609517 PMID:22647647 PMID:16324111 PMID:20524966 PMID:19959384 PMID:20736819 More...
RGD:4891885 , RGD:9491779 , RGD:9387859 , RGD:9354422 , RGD:4891942 , RGD:4892020
NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014
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Cxcl12
C-X-C motif chemokine ligand 12
IDA
RGD
PMID:28638088
RGD:13838657
NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
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Cxcr2
C-X-C motif chemokine receptor 2
IMP
RGD
PMID:19283893
RGD:5129125
NCBI chr 9:75,729,493...75,735,868
Ensembl chr 9:75,729,115...75,739,425
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Cxcr4
C-X-C motif chemokine receptor 4
treatment
IMP
RGD
PMID:28638088 PMID:30142543
RGD:13838657 , RGD:13838658
NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
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Cybb
cytochrome b-245 beta chain
ISO
associated with Spinal Cord Injuries;
RGD
PMID:20679217
RGD:11040629
NCBI chr X:13,358,101...13,392,570
Ensembl chr X:13,359,430...13,392,586
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Dlg4
discs large MAGUK scaffold protein 4
IDA
associated with Diabetic neuropathies;
RGD
PMID:20531396
RGD:7257680
NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153
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Drd3
dopamine receptor D3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20433900
NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596
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Dusp1
dual specificity phosphatase 1
treatment
IEP IDA
associated with Sciatic Neuropathy
RGD
PMID:22901764 PMID:22540262
RGD:7771531 , RGD:7771574
NCBI chr10:16,680,478...16,683,275
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Dusp6
dual specificity phosphatase 6
treatment
IEP
associated with Sciatic Neuropathy
RGD
PMID:22901764
RGD:7771531
NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185
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Edn1
endothelin 1
susceptibility
ISO
mRNA:increased expression:paw skin (mouse) CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:19429182 PMID:23347081 PMID:15664691
RGD:8661716 , RGD:8661735
NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
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Enpp2
ectonucleotide pyrophosphatase/phosphodiesterase 2
treatment
IMP
RGD
PMID:20392816
RGD:9685429
NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827
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Ep300
E1A binding protein p300
IMP
RGD
PMID:25263804
RGD:9588307
NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088 Ensembl chr 7:113,106,247...113,136,088
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Epha4
Eph receptor A4
IMP
associated with spinal cord injuries;
RGD
PMID:16959251
RGD:5688783
NCBI chr 9:78,815,460...78,958,139
Ensembl chr 9:78,815,460...78,958,139
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Ephx2
epoxide hydrolase 2
IMP
RGD
PMID:16962614
RGD:5688387
NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615
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Esr1
estrogen receptor 1
ISO
RGD
PMID:19285805
RGD:8553066
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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Esr2
estrogen receptor 2
IDA ISO
RGD
PMID:17056036 PMID:19285805
RGD:5508846 , RGD:8553066
NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
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F2
coagulation factor II, thrombin
ISO
associated with Sciatic Neuropathy
RGD
PMID:16251448
RGD:7387272
NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
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F2r
coagulation factor II (thrombin) receptor
severity
ISO IDA
RGD
PMID:19674841 PMID:11877315 PMID:12717003
RGD:7387269 , RGD:7387271 , RGD:7387270
NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870
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Fcgr1a
Fc gamma receptor 1A
ameliorates
IMP
RGD
PMID:32510872
RGD:127338469
NCBI chr 2:183,851,075...183,860,077
Ensembl chr 2:183,851,077...183,859,994
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Fos
Fos proto-oncogene, AP-1 transcription factor subunit
IEP ISO
protein:increased expression:dorsal horn of spinal cord, neuron CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:27093858 PMID:22160634
RGD:9999169
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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Fto
FTO, alpha-ketoglutarate dependent dioxygenase
treatment
ISO
associated with Cerebral Hemorrhage
RGD
PMID:34102854
RGD:329812008
NCBI chr19:15,284,898...15,692,142
Ensembl chr19:15,349,696...15,692,083
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Gal
galanin and GMAP prepropeptide
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12787826
NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959
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Gdnf
glial cell derived neurotrophic factor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20457222
NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209
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Gfap
glial fibrillary acidic protein
IEP ISO
associated with Spinal Cord Injuries;mRNA,protein:increased expression:brain,spinal cord: CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:27093858 PMID:16219025
RGD:8695957
NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
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Gfra1
GDNF family receptor alpha 1
IDA
RGD
PMID:16464682
RGD:6218969
NCBI chr 1:257,315,682...257,552,004
Ensembl chr 1:257,321,742...257,551,473
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Gja1
gap junction protein, alpha 1
treatment
IMP ISO IEP
associated with Sciatic Neuropathy CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:34286406 PMID:24631560 PMID:23374942
RGD:8662447 , RGD:8662456
NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
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Gper1
G protein-coupled estrogen receptor 1
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:25280432
NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889
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Grin1
glutamate ionotropic receptor NMDA type subunit 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:27093858
NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603
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Grin2a
glutamate ionotropic receptor NMDA type subunit 2A
IDA
RGD
PMID:29758384
RGD:13792698
NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637
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Grin2b
glutamate ionotropic receptor NMDA type subunit 2B
treatment
ISO IMP
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:20042082 PMID:24204988
RGD:13210755
NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279
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Grk2
G protein-coupled receptor kinase 2
treatment severity
IDA IMP IEP
associated with bone cancer associated with Complex Regional Pain Syndromes
RGD
PMID:26935064 PMID:26064176 PMID:25466829 PMID:22796071
RGD:13513996 , RGD:13514046 , RGD:13514049 , RGD:13792780
NCBI chr 1:201,580,823...201,601,580
Ensembl chr 1:201,581,480...201,601,582
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Grm8
glutamate metabotropic receptor 8
ISO
RGD
PMID:17113112
RGD:6771186
NCBI chr 4:55,805,762...56,731,690
Ensembl chr 4:55,805,955...56,730,831
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Hif1a
hypoxia inducible factor 1 subunit alpha
IEP
associated with Limb Ischemia;protein:increased expression:foot muscle, plantar
RGD
PMID:18691814
RGD:9068903
NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
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Hmgb1
high mobility group box 1
treatment
IEP IMP ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:27474498 PMID:24077211 PMID:30142543
RGD:7364865 , RGD:13838658
NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565 Ensembl chr16:5,901,586...5,978,565
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Hoxd1
homeo box D1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21151121
NCBI chr 3:59,665,629...59,667,769
Ensembl chr 3:59,665,629...59,667,769
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Htr2a
5-hydroxytryptamine receptor 2A
IDA ISO
associated with Diabetic neuropathies; CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:17888573 PMID:18930597 PMID:20531396
RGD:7257680
NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928
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Htr7
5-hydroxytryptamine receptor 7
IMP IDA
RGD
PMID:21693130 PMID:21843960
RGD:6480665 , RGD:6482179
NCBI chr 1:233,636,442...233,761,063
Ensembl chr 1:233,636,452...233,760,626
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Igf1
insulin-like growth factor 1
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:9452187
NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
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Il10
interleukin 10
treatment
IEP ISO IDA
associated with Sciatic Neuropathy CTD Direct Evidence: marker/mechanism|therapeutic
CTD RGD
PMID:7582491 PMID:17174526 PMID:23957449 PMID:24077211 PMID:22820166
RGD:7364792 , RGD:7364865 , RGD:7364827
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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Il13
interleukin 13
treatment
ISO
RGD
PMID:11399514
RGD:8549555
NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
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Il17a
interleukin 17A
treatment
IDA IMP
RGD
PMID:23192794 PMID:23246025
RGD:9068942 , RGD:9222699
NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
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Il18
interleukin 18
treatment
IMP
associated with Peripheral Nerve Injuries
RGD
PMID:19036970
RGD:8655929
NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
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Il1a
interleukin 1 alpha
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12727271
NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
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Il1b
interleukin 1 beta
IDA ISO
CTD Direct Evidence: marker/mechanism associated with Peripheral Nerve Injuries
CTD RGD
PMID:7582491 PMID:10401557 PMID:12727271 PMID:17320857 PMID:20937348 PMID:27093858 PMID:15317861 PMID:8741165 PMID:23159984 PMID:22265659 More...
RGD:1626676 , RGD:7401209 , RGD:7175548 , RGD:6482671
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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Il1r1
interleukin 1 receptor type 1
IMP ISO
RGD
PMID:19022353 PMID:11585580
RGD:8662898 , RGD:8662903
NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937
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Il1rn
interleukin 1 receptor antagonist
severity treatment
IDA ISO IMP
CTD Direct Evidence: marker/mechanism|therapeutic associated with Arthritis, Experimental; rat model treated with human protein
CTD RGD
PMID:8864563 PMID:15317861 PMID:17174526 PMID:20937348 PMID:23092240 PMID:10903985 PMID:17959986 PMID:22933159 More...
RGD:6909165 , RGD:8549800 , RGD:7401210 , RGD:6909175
NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
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Il2
interleukin 2
treatment
IMP IDA IEP
associated with Sciatic Neuropathy; mRNA,protein:increased expression:spinal cord:
RGD
PMID:12755376 PMID:18423867 PMID:22189457
RGD:8662973 , RGD:8662980 , RGD:8662977
NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
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Il33
interleukin 33
IMP
RGD
PMID:29329586
RGD:40400909
NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373
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Il6
interleukin 6
IEP ISO
associated with Foot Injuries; protein:increased expression:serum: CTD Direct Evidence: marker/mechanism mRNA:increased expression:dorsal root ganglion
CTD RGD
PMID:7582491 PMID:10401557 PMID:18652822 PMID:18988309 PMID:23953943
RGD:8662979 , RGD:10402830
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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Il6r
interleukin 6 receptor
IEP
mRNA:increased expression:dorsal root ganglion
RGD
PMID:23953943
RGD:10402830
NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536
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Insr
insulin receptor
treatment
ISO
associated with Diabetic Neuropathies CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:18331706 PMID:23511693
RGD:10403050
NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883
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Itga1
integrin subunit alpha 1
IMP
knock-down using a specific monoclonal antibody or RNAi PGE2-induced
RGD
PMID:15836982 PMID:14984413
RGD:2302139 , RGD:2302389
NCBI chr 2:46,646,125...46,812,237
Ensembl chr 2:46,653,193...46,812,238
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Itga2
integrin subunit alpha 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:18234883
NCBI chr 2:46,520,345...46,621,487
Ensembl chr 2:46,523,948...46,621,481
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Itga3
integrin subunit alpha 3
IMP
knock-down using a specific monoclonal antibody or RNAi
RGD
PMID:14984413 PMID:15836982
RGD:2302389 , RGD:2302139
NCBI chr10:79,990,160...80,022,206
Ensembl chr10:79,990,161...80,022,118
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Itga5
integrin subunit alpha 5
IMP
epinephrine-induced knock-down using a specific monoclonal antibody or RNAi
RGD
PMID:14984413 PMID:15836982
RGD:2302389 , RGD:2302139
NCBI chr 7:134,478,963...134,502,837
Ensembl chr 7:134,478,968...134,502,837
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Itgb1
integrin subunit beta 1
IMP
knock-down using a specific monoclonal antibody or RNAi
RGD
PMID:14984413 PMID:15836982
RGD:2302389 , RGD:2302139
NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
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Itpr1
inositol 1,4,5-trisphosphate receptor, type 1
IEP
RGD
PMID:25972297
RGD:13793383
NCBI chr 4:141,187,377...141,554,240
Ensembl chr 4:141,187,418...141,510,491
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Jak2
Janus kinase 2
treatment
IMP ISO
associated with Diabetic Neuropathies
RGD
PMID:18636982 PMID:23511693
RGD:6483031 , RGD:10403050
NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
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Jak3
Janus kinase 3
treatment
IEP
RGD
PMID:21434883
RGD:11533942
NCBI chr16:18,386,330...18,398,542
Ensembl chr16:18,386,405...18,398,536
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Kcnc4
potassium voltage-gated channel subfamily C member 4
IMP
RGD
PMID:17855600
RGD:10411908
NCBI chr 2:195,063,967...195,100,244
Ensembl chr 2:195,071,769...195,099,233
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Kcnk2
potassium two pore domain channel subfamily K member 2
ISO
RGD
PMID:16675954
RGD:9831112
NCBI chr13:100,766,101...100,963,435
Ensembl chr13:100,766,113...100,963,435
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Kcnq3
potassium voltage-gated channel subfamily Q member 3
IEP
associated with Bone Neoplasms;protein:decreased expression:dorsal root ganglia (rat)
RGD
PMID:23352759
RGD:9686417
NCBI chr 7:97,730,219...98,025,652
Ensembl chr 7:97,730,465...98,025,653
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Kmo
kynurenine 3-monooxygenase
treatment
IMP
RGD
PMID:26524415
RGD:13703043
NCBI chr13:87,557,080...87,589,334
Ensembl chr13:87,557,286...87,588,881
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Kng1
kininogen 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:2010815 PMID:2128375 PMID:3061568 PMID:7493622 PMID:7582491 PMID:7881729 PMID:9714424 PMID:9720808 PMID:10401557 PMID:10499367 PMID:10543429 PMID:15626726 PMID:16259764 PMID:16793879 PMID:18234883 PMID:21521205 More...
NCBI chr11:77,812,757...77,835,555
Ensembl chr11:77,812,752...77,835,555
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Kng2
kininogen 2
IDA
RGD
PMID:20868656
RGD:11059894
NCBI chr11:77,913,876...77,936,247
Ensembl chr11:77,909,612...78,002,971
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Lepr
leptin receptor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:29143802
NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
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Map1lc3a
microtubule-associated protein 1 light chain 3 alpha
IEP
RGD
PMID:23665054
RGD:11560531
NCBI chr 3:143,783,024...143,784,670
Ensembl chr 3:143,783,024...143,784,670
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Map2k3
mitogen activated protein kinase kinase 3
onset
ISO
RGD
PMID:19427893
RGD:7495807
NCBI chr10:45,608,145...45,629,492
Ensembl chr10:45,607,163...45,629,492
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Mapk1
mitogen activated protein kinase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12941468 PMID:27093858
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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Mapk3
mitogen activated protein kinase 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12941468 PMID:27093858
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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Mapk7
mitogen-activated protein kinase 7
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17237256
NCBI chr10:46,170,264...46,176,262
Ensembl chr10:46,170,167...46,176,267
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Mapk8
mitogen-activated protein kinase 8
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:27093858
NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
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Mapk9
mitogen-activated protein kinase 9
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:27093858
NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
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Mc1r
melanocortin 1 receptor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19996949
NCBI chr19:51,452,448...51,455,375
Ensembl chr19:51,453,239...51,454,192
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Mc4r
melanocortin 4 receptor
IEP
protein:increased expression:dorsal root ganglia (rat)
RGD
PMID:20081244
RGD:6484233
NCBI chr18:60,419,832...60,421,719
Ensembl chr18:60,419,832...60,421,719
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Mecp2
methyl CpG binding protein 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:33010341
NCBI chr X:151,781,177...151,844,687
Ensembl chr X:151,789,930...151,844,689
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Men1
menin 1
IEP
associated with Sciatic Neuropathy;protein:increased expression:spinal cord dorsal horn (rat)
RGD
PMID:20369282
RGD:9589142
NCBI chr 1:203,638,905...203,644,871
Ensembl chr 1:203,639,000...203,644,871
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Mfn2
mitofusin 2
IEP ISO
mRNA:decreased expression:spinal cord (rat) CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:28587902 PMID:28587902
RGD:12910704
NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
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Mir15b
microRNA 15b
IDA
RGD
PMID:28012171
RGD:13782150
NCBI chr 2:153,245,200...153,245,297
Ensembl chr 2:153,245,200...153,245,297
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Mir17
microRNA 17
severity
IMP
RGD
PMID:26222740
RGD:11074685
NCBI chr15:92,180,629...92,180,712
Ensembl chr15:92,180,629...92,180,712
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Mir381
microRNA 381
treatment
IDA
RGD
PMID:30142543
RGD:13838658
NCBI chr 6:128,740,976...128,741,036
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Mir96
microRNA 96
treatment
IDA
associated with Sciatic Neuropathy
RGD
PMID:24234845
RGD:11553932
NCBI chr 4:58,788,411...58,788,516
Ensembl chr 4:58,788,411...58,788,516
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Mmp3
matrix metallopeptidase 3
IMP ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:18754875 PMID:22056600
RGD:8693664
NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
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Mpz
myelin protein zero
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16676325
NCBI chr13:83,570,811...83,576,680
Ensembl chr13:83,570,811...83,576,679
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Mtor
mechanistic target of rapamycin kinase
IMP
RGD
PMID:24382350
RGD:10040983
NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
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Nefh
neurofilament heavy chain
treatment
IEP
RGD
PMID:21071147
RGD:27226885
NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351
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Ngf
nerve growth factor
treatment
ISO IMP IDA
associated with Cystitis CTD Direct Evidence: marker/mechanism associated with Peripheral Nerve Injuries;
CTD RGD
PMID:20457222 PMID:16203088 PMID:11425916 PMID:22839415 PMID:18448607
RGD:7242799 , RGD:8657088 , RGD:7242849 , RGD:7242803
NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
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Ngfr
nerve growth factor receptor
treatment
IMP
associated with Brachial Plexus Neuropathies
RGD
PMID:23324933
RGD:10413898
NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518
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Nlgn2
neuroligin 2
IMP
RGD
PMID:23891900
RGD:9831150
NCBI chr10:54,544,461...54,557,854
Ensembl chr10:54,544,588...54,558,434
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Nos1
nitric oxide synthase 1
IEP ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:19300402 PMID:23909597
RGD:7257597
NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
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Nos2
nitric oxide synthase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17989504 PMID:19300402
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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Npy
neuropeptide Y
treatment
IEP
associated with Sciatic Neuropathy
RGD
PMID:19556004
RGD:10448929
NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495
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Nrg1
neuregulin 1
IEP
associated with Sciatic Neuropathy
RGD
PMID:22212401
RGD:10449019
NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884
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Ntf3
neurotrophin 3
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:15659614
NCBI chr 4:158,914,984...158,984,453
Ensembl chr 4:158,914,957...158,984,596
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Ntrk1
neurotrophic receptor tyrosine kinase 1
IMP
RGD
PMID:17667845 PMID:20351485
RGD:5144120 , RGD:5684352
NCBI chr 2:173,236,961...173,253,806
Ensembl chr 2:173,236,963...173,253,770
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Ntrk2
neurotrophic receptor tyrosine kinase 2
ISO IEP
associated with inflammation;protein:increased expression:dorsal root ganglion:
RGD
PMID:12470870 PMID:21958434
RGD:8657091 , RGD:8657122
NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136
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Ntsr1
neurotensin receptor 1
IDA
RGD
PMID:22396077
RGD:9743902
NCBI chr 3:167,606,215...167,656,371
Ensembl chr 3:167,606,215...167,656,377
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Oprk1
opioid receptor, kappa 1
treatment
IMP
associated with Diabetes Mellitus, Experimental;
RGD
PMID:16924480
RGD:9834947
NCBI chr 5:13,860,016...13,877,823
Ensembl chr 5:13,860,021...13,877,823
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Oprl1
opioid related nociceptin receptor 1
IEP
associated with Sciatic Neuropathy;mRNA:increased expression:spinal cord lumbar segment,dorsal root ganglion:
RGD
PMID:12106803
RGD:9835017
NCBI chr 3:168,831,934...168,839,920
Ensembl chr 3:168,834,003...168,839,920
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Oprm1
opioid receptor, mu 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17996026
NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409
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P2rx2
purinergic receptor P2X 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19383439
NCBI chr12:46,338,979...46,342,891
Ensembl chr12:46,339,549...46,342,891
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P2rx3
purinergic receptor P2X 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19383439
NCBI chr 3:70,080,850...70,124,664
Ensembl chr 3:70,080,851...70,125,178
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P2rx4
purinergic receptor P2X 4
treatment
IMP
associated with Peripheral Nerve Injuries;
RGD
PMID:29927790
RGD:40924654
NCBI chr12:33,844,609...33,862,265
Ensembl chr12:33,844,396...33,862,253
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P2ry12
purinergic receptor P2Y12
ISO IMP
RGD
PMID:20398327 PMID:20136836
RGD:6480525 , RGD:6480526
NCBI chr 2:143,481,468...143,523,340
Ensembl chr 2:143,481,430...143,523,361
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Pawr
pro-apoptotic WT1 regulator
treatment
IDA
RGD
PMID:17179954
RGD:9835416
NCBI chr 7:43,645,028...43,725,033
Ensembl chr 7:43,645,084...43,725,028
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Pdyn
prodynorphin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17670969
NCBI chr 3:116,900,990...116,913,334
Ensembl chr 3:116,900,992...116,913,334
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Penk
proenkephalin
treatment
ISO
associated with Diabetes Mellitus, Experimental;
RGD
PMID:23235561
RGD:10003116
NCBI chr 5:17,183,799...17,189,160
Ensembl chr 5:17,183,806...17,189,129
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Pla2g4a
phospholipase A2 group IVA
IMP
RGD
PMID:16203828
RGD:1642461
NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266
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Pnoc
prepronociceptin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12665541 PMID:19231294
NCBI chr15:39,624,635...39,652,463
Ensembl chr15:39,624,641...39,651,867
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Ppp2ca
protein phosphatase 2 catalytic subunit alpha
IMP
RGD
PMID:26732138
RGD:11572421
NCBI chr10:36,358,110...36,377,864
Ensembl chr10:36,358,101...36,377,862
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Prkcb
protein kinase C, beta
IDA
associated with inflammation;protein:increased activity:spinal cord
RGD
PMID:16360284
RGD:1625519
NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536
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Prkce
protein kinase C, epsilon
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:11738263 PMID:12582831 PMID:20457222
NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719
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Prkcg
protein kinase C, gamma
treatment
ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:19955894 PMID:27093858 PMID:12560106
RGD:28867224
NCBI chr 1:65,832,851...65,860,676
Ensembl chr 1:65,832,855...65,859,384
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Prkcz
protein kinase C, zeta
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:27899695
NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367
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Prkg1
protein kinase cGMP-dependent 1
treatment
ISO
RGD
PMID:14973199
RGD:7775058
NCBI chr 1:228,409,605...229,638,794
Ensembl chr 1:228,408,947...229,639,080
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Prok2
prokineticin 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16793879
NCBI chr 4:132,346,681...132,361,754
Ensembl chr 4:132,347,103...132,361,385
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Prokr1
prokineticin receptor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16793879
NCBI chr 4:120,022,301...120,033,367
Ensembl chr 4:120,021,747...120,033,379
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Ptafr
platelet-activating factor receptor
treatment
IMP
RGD
PMID:16925995
RGD:10041052
NCBI chr 5:144,765,770...144,795,057
Ensembl chr 5:144,765,976...144,795,251
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Ptger1
prostaglandin E receptor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:11375261
NCBI chr19:24,470,258...24,473,687
Ensembl chr19:24,467,532...24,473,559
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Ptger3
prostaglandin E receptor 3
IEP
protein:increased expression:lumbar spinal cord dorsal horn (rat)
RGD
PMID:17413918
RGD:5688169
NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434
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Ptger4
prostaglandin E receptor 4
treatment
IMP
RGD
PMID:20423341
RGD:10003041
NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670
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Ptges3
prostaglandin E synthase 3
IMP
RGD
PMID:16192391
RGD:5688057
NCBI chr 7:490,698...507,759
Ensembl chr 7:490,656...508,084
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Ptgs1
prostaglandin-endoperoxide synthase 1
IEP ISO
protein:increased expression:spinal cord CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:17989504 PMID:17413918
RGD:5688169
NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586
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Ptgs2
prostaglandin-endoperoxide synthase 2
IMP ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:17112505 PMID:17989504 PMID:15464832
RGD:5688224
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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Pthlh
parathyroid hormone-like hormone
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16769263
NCBI chr 4:180,188,792...180,199,847
Ensembl chr 4:180,188,792...180,199,847
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Raf1
Raf-1 proto-oncogene, serine/threonine kinase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:18976650
NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317
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Rgs4
regulator of G-protein signaling 4
treatment
IMP
associated with lesion of sciatic nerve
RGD
PMID:27641322
RGD:13524513
NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068
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Scn10a
sodium voltage-gated channel alpha subunit 10
IMP ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:16545521 PMID:19070548
RGD:6484253
NCBI chr 8:119,350,723...119,462,882
Ensembl chr 8:119,350,724...119,462,614
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Scn11a
sodium voltage-gated channel alpha subunit 11
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23264124
NCBI chr 8:119,495,550...119,567,044
Ensembl chr 8:119,496,769...119,567,044
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Sin3a
SIN3 transcription regulator family member A
IEP
associated with Arthritis, Experimental;mRNA:decreased expression:spinal cord, neuron
RGD
PMID:17553988
RGD:9495916
NCBI chr 8:57,481,539...57,536,195
Ensembl chr 8:57,481,573...57,536,192
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Slc12a5
solute carrier family 12 member 5
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20086212
NCBI chr 3:153,696,517...153,735,801
Ensembl chr 3:153,696,517...153,735,765
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Slc17a8
solute carrier family 17 member 8
IEP
protein:increased expression:dorsal horn of spinal cord, neuron
RGD
PMID:22160634
RGD:9999169
NCBI chr 7:23,994,212...24,049,498
Ensembl chr 7:23,994,217...24,048,079
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Sparc
secreted protein acidic and cysteine rich
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20714283
NCBI chr10:39,516,394...39,538,252
Ensembl chr10:39,516,406...39,538,396
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Stat3
signal transducer and activator of transcription 3
treatment
IMP
RGD
PMID:24098399
RGD:8694290
NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
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Syn2
synapsin II
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:18701217
NCBI chr 4:148,178,846...148,347,010
Ensembl chr 4:148,186,270...148,344,192
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Tac1
tachykinin, precursor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:8864563 PMID:9714424 PMID:10499367 PMID:12351280 PMID:12787826 PMID:15626726 PMID:16259764 PMID:18234883 PMID:19231294 More...
NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178
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Tacr1
tachykinin receptor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:15964684 PMID:17123731
NCBI chr 4:114,920,844...115,089,733
Ensembl chr 4:114,920,844...115,089,733
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Tcf7l2
transcription factor 7 like 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:33607128
NCBI chr 1:254,785,956...254,978,967
Ensembl chr 1:254,786,091...254,978,967
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Tgfbr1
transforming growth factor, beta receptor 1
IMP
associated with Experimental Pancreatitis, Chronic
RGD
PMID:26645248
RGD:14995470
NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777
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Thbd
thrombomodulin
treatment
ISO
associated with Inflammation CTD Direct Evidence: therapeutic
CTD RGD
PMID:27474498 PMID:24004409
RGD:11038687
NCBI chr 3:135,863,366...135,867,018
Ensembl chr 3:135,862,835...135,867,193
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Tlr2
toll-like receptor 2
ISO IDA
RGD
PMID:17355971 PMID:24204973
RGD:8553059 , RGD:8553185
NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630
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Tlr4
toll-like receptor 4
IMP ISO
RGD
PMID:20714435 PMID:24204973 PMID:15809417
RGD:4144070 , RGD:8553185 , RGD:7815040
NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
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Tnf
tumor necrosis factor
IMP ISO IDA IEP
CTD Direct Evidence: marker/mechanism associated with Diabetic Neuropathies; mRNA,protein:increased expression:spinal cord: protein:increased expression:lumbar vertebra:
CTD RGD
PMID:7582491 PMID:7881729 PMID:10401557 PMID:12727271 PMID:16472913 PMID:17320857 PMID:18463260 PMID:18582539 PMID:20383154 PMID:26141506 PMID:27093858 PMID:16675114 PMID:21104419 PMID:17304130 PMID:10825476 PMID:18790011 PMID:17459378 PMID:16675114 More...
RGD:7387300 , RGD:7401179 , RGD:7394757 , RGD:7394741 , RGD:7394737 , RGD:7387302 , RGD:7387300
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Tnfrsf11b
TNF receptor superfamily member 11B
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:16769263
NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538
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Tnfrsf1a
TNF receptor superfamily member 1A
treatment
IMP IEP ISO
associated with Sciatic Neuropathy
RGD
PMID:12752784 PMID:22652595 PMID:21712071 PMID:24257399 PMID:20417692 PMID:21145890 More...
RGD:5130913 , RGD:8661750 , RGD:8548873 , RGD:8661737 , RGD:8661726 , RGD:5130939
NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
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Tnfrsf1b
TNF receptor superfamily member 1B
ISO IMP
associated with Sciatic Neuropathy
RGD
PMID:18463260 PMID:22652595
RGD:5130960 , RGD:8661750
NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206
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Trpa1
transient receptor potential cation channel, subfamily A, member 1
IMP ISO
associated with Peripheral Nerve Injuries; CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:18234885 PMID:21481532 PMID:23523557 PMID:18954467
RGD:10043618
NCBI chr 5:4,379,862...4,434,133
Ensembl chr 5:4,379,999...4,433,570
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Trpc1
transient receptor potential cation channel, subfamily C, member 1
IMP
associated with Inflammation
RGD
PMID:19439599
RGD:7247605
NCBI chr 8:96,263,322...96,314,220
Ensembl chr 8:96,263,329...96,314,276
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Trpc6
transient receptor potential cation channel, subfamily C, member 6
IMP
RGD
PMID:19439599
RGD:7247605
NCBI chr 8:5,759,387...5,864,000
Ensembl chr 8:5,758,935...5,828,092
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Trpv1
transient receptor potential cation channel, subfamily V, member 1
IEP ISO
associated with inflammation;protein:increased expression:dorsal root ganglion: CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:12151517 PMID:18234885 PMID:18774343 PMID:23006841 PMID:21958434
RGD:8657122
NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
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Trpv4
transient receptor potential cation channel, subfamily V, member 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:18234883
NCBI chr12:41,938,533...41,977,517
Ensembl chr12:41,938,560...41,977,517
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Vip
vasoactive intestinal peptide
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12787826
NCBI chr 1:42,064,878...42,073,219
Ensembl chr 1:42,065,120...42,073,216
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Kng1
kininogen 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:8190269
NCBI chr11:77,812,757...77,835,555
Ensembl chr11:77,812,752...77,835,555
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Aqp4
aquaporin 4
ISO
RGD
PMID:20851747
RGD:8696005
NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856
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Hdac4
histone deacetylase 4
ISO
RGD
PMID:19672313
RGD:9681457
NCBI chr 9:92,503,467...92,750,164
Ensembl chr 9:92,507,611...92,750,164
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Eif1ax
eukaryotic translation initiation factor 1A, X-linked
ISO
ClinVar Annotator: match by term: Choroidal melanoma
ClinVar
PMID:25741868
NCBI chr X:35,498,698...35,513,402
Ensembl chr X:35,498,517...35,513,335
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Tmem127
transmembrane protein 127
ISO
ClinVar Annotator: match by term: Intraocular melanoma
ClinVar
PMID:25741868 PMID:28492532
NCBI chr 3:114,466,095...114,478,894
Ensembl chr 3:114,466,171...114,477,519
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Capn3
calpain 3
ISO
ClinVar Annotator: match by term: Paresthesia
ClinVar
PMID:7720071 PMID:9266733 PMID:10330340 PMID:10679950 PMID:14578192 PMID:14981715 PMID:15221789 PMID:15351423 PMID:15689361 PMID:15725583 PMID:16100770 PMID:16141003 PMID:16372320 PMID:16411092 PMID:16650086 PMID:17157502 PMID:17236769 PMID:17318636 PMID:17702496 PMID:17979987 PMID:18055493 PMID:20635405 PMID:21204801 PMID:21984748 PMID:24803842 PMID:25135358 PMID:25741868 PMID:26301378 PMID:26404900 PMID:26467025 PMID:26484845 PMID:27142102 PMID:27708273 PMID:27884173 PMID:28492532 PMID:28877744 PMID:28914264 PMID:30028523 PMID:30919934 PMID:31263448 PMID:31517061 PMID:31788660 More...
NCBI chr 3:107,407,518...107,457,858
Ensembl chr 3:107,407,850...107,457,858
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Fkrp
fukutin related protein
ISO
ClinVar Annotator: match by term: Paresthesia
ClinVar
PMID:11741828 PMID:12666124 PMID:14647208 PMID:15060126 PMID:15574464 PMID:15580560 PMID:15833432 PMID:15883334 PMID:15886712 PMID:16344347 PMID:16634037 PMID:16786213 PMID:17554798 PMID:18060779 PMID:18593008 PMID:18639457 PMID:19705481 PMID:19820980 PMID:19835634 PMID:19900540 PMID:20961759 PMID:21220724 PMID:21228398 PMID:22264518 PMID:22981120 PMID:23576288 PMID:23591631 PMID:24033266 PMID:24447024 PMID:25048216 PMID:25560911 PMID:25741868 PMID:26363967 PMID:26467025 PMID:26574668 PMID:26833294 PMID:28112097 PMID:28479227 PMID:28492532 PMID:30232282 PMID:30417025 PMID:30564623 PMID:30919934 PMID:31268217 PMID:34008892 PMID:34653404 More...
NCBI chr 1:77,479,641...77,486,954
Ensembl chr 1:77,476,084...77,486,992
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Ins2
insulin 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:9861226
NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
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Pmp22
peripheral myelin protein 22
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12427913
NCBI chr10:47,795,709...47,825,715
Ensembl chr10:47,795,709...47,825,714
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Cadm2
cell adhesion molecule 2
ISO
mRNA, protein:decreased expression:retina
RGD
PMID:30320366
RGD:15092072
NCBI chr11:4,548,367...5,525,420
Ensembl chr11:4,555,159...5,525,400
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Cdkn2a
cyclin-dependent kinase inhibitor 2A
ISO
ClinVar Annotator: match by term: Retinoblastoma
ClinVar
PMID:25741868 PMID:28492532
NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
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Dicer1
dicer 1 ribonuclease III
exacerbates
ISO
DNA:deletion:haploinsufficiency
RGD
PMID:20019750
RGD:149735324
NCBI chr 6:123,627,529...123,692,278
Ensembl chr 6:123,631,250...123,693,965
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Fancm
FA complementation group M
ISO
ClinVar Annotator: match by term: Retinoblastoma
ClinVar
PMID:25741868
NCBI chr 6:83,126,903...83,180,455
Ensembl chr 6:83,127,093...83,180,028
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Fas
Fas cell surface death receptor
severity
ISO
protein:decreased expression:tumor (human)
RGD
PMID:14533029
RGD:8662811
NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
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Ifnb1
interferon beta 1
ameliorates
ISO
RGD
PMID:19306089
RGD:401854248
NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523
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Itm2b
integral membrane protein 2B
ISO
ClinVar Annotator: match by term: Eye cancer, retinoblastoma | ClinVar Annotator: match by term: Retinoblastoma
ClinVar
PMID:8099255 PMID:12541220 PMID:14722923 PMID:15877282 PMID:17096365 PMID:17301081 PMID:22180099 PMID:25741868 PMID:26475597 PMID:28492532 PMID:28575107 PMID:29568217 More...
NCBI chr15:48,545,998...48,568,904
Ensembl chr15:48,546,001...48,568,917
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Kdm1b
lysine demethylase 1B
ISO
mRNA:increased expression:retina (human)
RGD
PMID:16180235
RGD:9588276
NCBI chr17:17,602,961...17,643,865
Ensembl chr17:17,602,961...17,643,800
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Lpar6
lysophosphatidic acid receptor 6
ISO
ClinVar Annotator: match by term: Eye cancer, retinoblastoma | ClinVar Annotator: match by term: Retinoblastoma
ClinVar
PMID:8099255 PMID:12541220 PMID:15877282 PMID:17096365 PMID:17301081 PMID:21505449 PMID:22909775 PMID:23301675 PMID:25640679 PMID:25741868 PMID:26475597 PMID:28492532 PMID:28575107 PMID:29568217 More...
NCBI chr15:48,416,548...48,418,357
Ensembl chr15:48,416,544...48,422,331
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Max
MYC associated factor X
ISO
ClinVar Annotator: match by term: Retinoblastoma
ClinVar
PMID:25741868 PMID:28492532
NCBI chr 6:95,636,859...95,662,204
Ensembl chr 6:95,636,858...95,662,137
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Med4
mediator complex subunit 4
ISO
ClinVar Annotator: match by term: Eye cancer, retinoblastoma | ClinVar Annotator: match by term: Retinoblastoma
ClinVar
PMID:8099255 PMID:12541220 PMID:14722923 PMID:15877282 PMID:17096365 PMID:17301081 PMID:22180099 PMID:26475597 PMID:28492532 PMID:28575107 PMID:29568217 More...
NCBI chr15:48,696,542...48,706,818
Ensembl chr15:48,696,511...48,706,820
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Mgmt
O-6-methylguanine-DNA methyltransferase
disease_progression
ISO
DNA:hypermethylation:promoter (human)
RGD
PMID:15799820
RGD:2317684
NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
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Mir182
microRNA 182
treatment
IEP IMP
miRNA:increased expression:retina
RGD
PMID:30320366 PMID:30320366
RGD:15092072 , RGD:15092072
NCBI chr 4:58,784,818...58,784,879
Ensembl chr 4:58,784,818...58,784,879
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Mtr
5-methyltetrahydrofolate-homocysteine methyltransferase
susceptibility
ISO
DNA:SNP::2756A>G(human)
RGD
PMID:20310006
RGD:8694083
NCBI chr17:58,219,998...58,308,560
Ensembl chr17:58,220,071...58,304,822
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Mutyh
mutY DNA glycosylase
ISO
ClinVar Annotator: match by term: Retinoblastoma
ClinVar
PMID:25741868 PMID:26947005 PMID:28135145 PMID:28492532 PMID:30267214
NCBI chr 5:130,274,034...130,286,149
Ensembl chr 5:130,274,122...130,286,146
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Nf1
neurofibromin 1
ISO
ClinVar Annotator: match by term: Retinoblastoma
ClinVar
PMID:25741868 PMID:28492532
NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658
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Nudt15
nudix hydrolase 15
ISO
ClinVar Annotator: match by term: Retinoblastoma
ClinVar
PMID:8099255 PMID:12541220 PMID:14722923 PMID:17096365 PMID:22180099 PMID:28492532 PMID:28575107 PMID:29568217 More...
NCBI chr15:48,707,776...48,713,847
Ensembl chr15:48,709,700...48,747,363
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Palb2
partner and localizer of BRCA2
ISO
ClinVar Annotator: match by term: Retinoblastoma
ClinVar
PMID:23555315 PMID:25085752 PMID:25741868 PMID:26467025 PMID:28492532 PMID:28873162 PMID:32832836 PMID:32868316 More...
NCBI chr 1:176,665,076...176,689,053
Ensembl chr 1:176,665,076...176,688,990
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Ptch1
patched 1
ISO
ClinVar Annotator: match by term: Retinoblastoma
ClinVar
PMID:24728327 PMID:25741868 PMID:28492532
NCBI chr17:1,542,705...1,607,730
Ensembl chr17:1,542,877...1,607,333
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Rb1
RB transcriptional corepressor 1
ISO
ClinVar Annotator: match by term: Eye cancer, retinoblastoma | ClinVar Annotator: match by term: Retinoblastoma CTD Direct Evidence: marker/mechanism DNA:mutations:exon, intron:multiple
OMIM ClinVar CTD RGD
PMID:1298292 PMID:1352398 PMID:1352883 PMID:1534305 PMID:1577465 PMID:1662795 PMID:1881452 PMID:2181449 PMID:2594029 PMID:2601691 PMID:2673542 PMID:2748600 PMID:7704558 PMID:7795591 PMID:7881418 PMID:7927327 PMID:7981694 PMID:8099255 PMID:8118465 PMID:8346255 PMID:8364580 PMID:8605116 PMID:8651278 PMID:8756645 PMID:8776589 PMID:9311732 PMID:9341870 PMID:9400934 PMID:9495340 PMID:9536098 PMID:9632788 PMID:9639842 PMID:9671401 PMID:9973307 PMID:10023315 PMID:10486322 PMID:10617920 PMID:10671068 PMID:10673998 PMID:10882758 PMID:10966849 PMID:10991691 PMID:11189328 PMID:11317357 PMID:11317369 PMID:11333669 PMID:11480772 PMID:11668642 PMID:12016586 PMID:12173465 PMID:12402348 PMID:12502741 PMID:12541220 PMID:12955724 PMID:14516425 PMID:14722923 PMID:14769601 PMID:15166261 PMID:15591264 PMID:15605413 PMID:15643604 PMID:15776430 PMID:15877282 PMID:15884040 PMID:16127685 PMID:16199547 PMID:16269091 PMID:16343894 PMID:16449662 PMID:16463005 PMID:16595082 PMID:16988938 PMID:17096365 PMID:17299438 PMID:17301081 PMID:17576681 PMID:17960112 PMID:17996702 PMID:18000883 PMID:18181215 PMID:18449911 PMID:18503160 PMID:18677112 PMID:18682685 PMID:19280657 PMID:19339519 PMID:19390654 PMID:19491728 PMID:19763152 PMID:20041224 PMID:20059380 PMID:20090211 PMID:20307669 PMID:20447117 PMID:20594292 PMID:20596833 PMID:20808897 PMID:21402997 PMID:21505449 PMID:21520333 PMID:21538077 PMID:21615945 PMID:21654082 PMID:21763628 PMID:22084214 PMID:22180099 PMID:22205104 PMID:22219649 PMID:22328814 PMID:22406018 PMID:22703879 PMID:22744425 PMID:22909775 PMID:22963398 PMID:23301675 PMID:23474753 PMID:23532519 PMID:23595191 PMID:23820649 PMID:23981928 PMID:24033266 PMID:24078560 PMID:24082139 PMID:24225018 PMID:24336570 PMID:24347427 PMID:24448499 PMID:24509483 PMID:24688104 PMID:24728327 PMID:24791139 PMID:24810223 PMID:24888624 PMID:25157968 PMID:25424699 PMID:25525159 PMID:25602518 PMID:25640679 PMID:25712084 PMID:25741868 PMID:25754945 PMID:25758528 PMID:25928201 PMID:25999316 PMID:26084579 PMID:26332594 PMID:26396485 PMID:26475597 PMID:26530098 PMID:26539030 PMID:26580448 PMID:26747767 PMID:26764160 PMID:26787237 PMID:26925970 PMID:26934580 PMID:27021801 PMID:27153395 PMID:27155049 PMID:27283993 PMID:27582626 PMID:27854218 PMID:27879208 PMID:27906792 PMID:27983729 PMID:28193182 PMID:28301456 PMID:28401291 PMID:28492532 PMID:28575107 PMID:28580595 PMID:28606269 PMID:28724667 PMID:28803391 PMID:28873162 PMID:28875981 PMID:29192238 PMID:29261756 PMID:29316426 PMID:29453956 PMID:29568217 PMID:29607586 PMID:29625052 PMID:29641532 PMID:29662154 PMID:29684080 PMID:30031154 PMID:30181556 PMID:30192042 PMID:30636860 PMID:30773851 PMID:30842500 PMID:31106028 PMID:31568710 PMID:31645765 PMID:31772335 PMID:32091409 PMID:32218800 PMID:32974172 PMID:33225895 PMID:33456302 PMID:33493472 PMID:33606809 PMID:34190019 PMID:34294096 PMID:34308366 PMID:34680218 PMID:12402348 More...
RGD:8547986
NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
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Serpinf1
serpin family F member 1
treatment
ISO
human protein and tumor xenograft in a mouse model
RGD
PMID:19832843
RGD:8554870
NCBI chr10:60,250,198...60,262,593
Ensembl chr10:60,249,708...60,262,646
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Sncg
synuclein, gamma
ISO
RGD
PMID:18728752
RGD:6218971
NCBI chr16:9,700,513...9,705,751
Ensembl chr16:9,700,514...9,705,368
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Rb1
RB transcriptional corepressor 1
ISO
ClinVar Annotator: match by term: Trilateral retinoblastoma
ClinVar
PMID:7704558 PMID:8346255 PMID:8605116 PMID:9400934 PMID:16463005 PMID:17096365 PMID:21763628 PMID:22963398 PMID:24688104 PMID:25157968 PMID:25602518 PMID:25741868 PMID:28492532 PMID:30031154 PMID:33456302 More...
NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
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Bap1
Brca1 associated protein 1
disease_progression
ISO
mRNA,protein:decreased expression: : ClinVar Annotator: match by term: Melanoma, uveal, susceptibility to, 2 | ClinVar Annotator: match by term: Uveal melanoma CTD Direct Evidence: marker/mechanism
OMIM ClinVar CTD RGD
PMID:16341802 PMID:19197335 PMID:21874000 PMID:23032617 PMID:23684012 PMID:24243779 PMID:24728327 PMID:25231345 PMID:25687217 PMID:25741868 PMID:25974357 PMID:26467025 PMID:26556299 PMID:26683624 PMID:26719535 PMID:28062663 PMID:28492532 PMID:28551647 PMID:28793149 PMID:30477459 PMID:30883995 PMID:31034483 PMID:31186267 PMID:32002398 PMID:25147369 More...
RGD:9586037
NCBI chr16:6,446,709...6,455,535
Ensembl chr16:6,446,709...6,455,535
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Birc7
baculoviral IAP repeat-containing 7
exacerbates
ISO
mRNA:increased expression:uvea (human)
RGD
PMID:31964418
RGD:153344516
NCBI chr 3:168,047,824...168,052,606
Ensembl chr 3:168,047,824...168,052,606
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Brca2
BRCA2, DNA repair associated
susceptibility
ISO
DNA:mutations: :
RGD
PMID:22187320
RGD:9068467
NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
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Crp
C-reactive protein
disease_progression
ISO
RGD
PMID:23057648
RGD:9491834
NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178
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Cysltr2
cysteinyl leukotriene receptor 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:27089179 PMID:33288675
NCBI chr15:48,189,476...48,228,750
Ensembl chr15:48,189,073...48,304,136
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Eif1ax
eukaryotic translation initiation factor 1A, X-linked
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23793026
NCBI chr X:35,498,698...35,513,402
Ensembl chr X:35,498,517...35,513,335
G
Gna11
G protein subunit alpha 11
ISO
CTD Direct Evidence: marker/mechanism ClinVar Annotator: match by term: Uveal melanoma
CTD ClinVar
PMID:1328859 PMID:2549426 PMID:21083380 PMID:21444680 PMID:22733540 PMID:22808163 PMID:24141786 PMID:25157968 PMID:25741868 PMID:26397223 PMID:26619011 PMID:27089179 More...
NCBI chr 7:8,163,520...8,177,863
Ensembl chr 7:8,162,750...8,179,812
G
Gnaq
G protein subunit alpha q
ISO
CTD Direct Evidence: marker/mechanism ClinVar Annotator: match by term: Uveal melanoma
CTD ClinVar
PMID:1328859 PMID:2549426 PMID:18719078 PMID:19078957 PMID:21083380 PMID:22253748 PMID:22653968 PMID:22733540 PMID:22808163 PMID:25157968 PMID:26397223 PMID:27089179 More...
NCBI chr 1:213,425,631...213,671,947
Ensembl chr 1:213,424,465...213,667,672
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Igf1
insulin-like growth factor 1
disease_progression
ISO
RGD
PMID:23197685
RGD:8548834
NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
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Jmjd6
jumonji domain containing 6, arginine demethylase and lysine hydroxylase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:30619488
NCBI chr10:102,041,131...102,047,182
Ensembl chr10:102,041,120...102,047,182
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Kdm5b
lysine demethylase 5B
severity
ISO
protein:increased expression:uvea (human)
RGD
PMID:22669717
RGD:9587775
NCBI chr13:46,001,589...46,073,868
Ensembl chr13:46,002,542...46,073,872
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Kdr
kinase insert domain receptor
disease_progression
ISO
RGD
PMID:21984395
RGD:8549718
NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
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Mbd4
methyl-CpG binding domain 4 DNA glycosylase
ISO
ClinVar Annotator: match by term: Melanoma, uveal, susceptibility to, 1 CTD Direct Evidence: marker/mechanism
ClinVar OMIM CTD
PMID:28492532 PMID:29760383 PMID:30049810 PMID:30714079 PMID:32239153 PMID:35460607 More...
NCBI chr 4:148,893,049...148,904,833
Ensembl chr 4:148,894,280...148,904,982
G
Mcam
melanoma cell adhesion molecule
disease_progression
ISO
RGD
PMID:19958117
RGD:7364775
NCBI chr 8:44,479,391...44,487,575
Ensembl chr 8:44,479,376...44,487,571
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Plcb4
phospholipase C, beta 4
ISO
CTD Direct Evidence: marker/mechanism ClinVar Annotator: match by term: Uveal melanoma
CTD ClinVar
PMID:27089179 PMID:31186267
NCBI chr 3:122,952,965...123,322,522
Ensembl chr 3:122,953,196...123,322,392
G
Pramex1
PRAME like, X-linked 1
severity
ISO
mRNA:increased expression:uvea (human)
RGD
PMID:27486988
RGD:11535039
NCBI chr X:98,567,994...98,574,654
Ensembl chr X:98,569,415...98,572,096
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RT1-CE13
RT1 class I, locus CE13
severity
ISO
protein:increased expression:tumor of uvea (human)
RGD
PMID:9286277
RGD:7364941
NCBI chr20:3,314,830...3,318,106
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Serpine1
serpin family E member 1
treatment
ISO
human gene in mouse model
RGD
PMID:9326241
RGD:8547806
NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
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Serpinf1
serpin family F member 1
severity
ISO
RGD
PMID:23793989
RGD:8554893
NCBI chr10:60,250,198...60,262,593
Ensembl chr10:60,249,708...60,262,646
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Sf3b1
splicing factor 3b, subunit 1
ISO
CTD Direct Evidence: marker/mechanism ClinVar Annotator: match by term: Uveal melanoma
CTD ClinVar
PMID:23313955 PMID:23793026 PMID:25741868 PMID:26619011
NCBI chr 9:56,492,403...56,532,300
Ensembl chr 9:56,492,403...56,532,300
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Tmem127
transmembrane protein 127
ISO
ClinVar Annotator: match by term: Uveal melanoma
ClinVar
PMID:25741868 PMID:28492532
NCBI chr 3:114,466,095...114,478,894
Ensembl chr 3:114,466,171...114,477,519
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Vegfa
vascular endothelial growth factor A
ISO
protein:increased expression:iris, ciliary body, vitreous body;
RGD
PMID:11914216
RGD:7483591
NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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