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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Brain Abscess
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Accession:DOID:9008595 term browser browse the term
Definition:A circumscribed collection of purulent exudate in the brain, due to bacterial and other infections. The majority are caused by spread of infected material from a focus of suppuration elsewhere in the body, notably the PARANASAL SINUSES, middle ear (see EAR, MIDDLE); HEART (see also ENDOCARDITIS, BACTERIAL), and LUNG. Penetrating CRANIOCEREBRAL TRAUMA and NEUROSURGICAL PROCEDURES may also be associated with this condition. Clinical manifestations include HEADACHE; SEIZURES; focal neurologic deficits; and alterations of consciousness. (Adams et al., Principles of Neurology, 6th ed, pp712-6)
Synonyms:exact_synonym: Brain Abscesses;   Cerebral Abscess;   Cerebral Abscesses;   Child Brain Abscess;   Multiple Brain Abscess;   Multiple Brain Abscesses;   Pyogenic Brain Abscess;   Pyogenic Brain Abscesses;   Sterile Brain Abscess;   Sterile Brain Abscesses
 primary_id: MESH:D001922
For additional species annotation, visit the Alliance of Genome Resources.



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Brain Abscess term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TLR2 toll like receptor 2 ISO RGD PMID:16239543 RGD:8552881 NCBI chr15:51,454,557...51,465,429
Ensembl chr15:51,454,695...51,465,241
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Cerebral Toxoplasmosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NFKB1 nuclear factor kappa B subunit 1 severity ISO RGD PMID:20156658 RGD:40902838 NCBI chr32:23,948,598...24,040,704
Ensembl chr32:23,942,954...24,040,703
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14734
    disease by infectious agent 2040
      Bacterial Infections and Mycoses 925
        Central Nervous System Infections 254
          Brain Abscess 2
            Cerebral Toxoplasmosis 1
Path 2
Term Annotations click to browse term
  disease 14734
    disease of anatomical entity 14414
      Immune & Inflammatory Diseases 4562
        Inflammation 2413
          Suppuration 102
            Abscess 10
              Brain Abscess 2
                Cerebral Toxoplasmosis 1
paths to the root