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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Brain Abscess
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Accession:DOID:9008595 term browser browse the term
Definition:A circumscribed collection of purulent exudate in the brain, due to bacterial and other infections. The majority are caused by spread of infected material from a focus of suppuration elsewhere in the body, notably the PARANASAL SINUSES, middle ear (see EAR, MIDDLE); HEART (see also ENDOCARDITIS, BACTERIAL), and LUNG. Penetrating CRANIOCEREBRAL TRAUMA and NEUROSURGICAL PROCEDURES may also be associated with this condition. Clinical manifestations include HEADACHE; SEIZURES; focal neurologic deficits; and alterations of consciousness. (Adams et al., Principles of Neurology, 6th ed, pp712-6)
Synonyms:exact_synonym: Brain Abscesses;   Cerebral Abscess;   Cerebral Abscesses;   Child Brain Abscess;   Multiple Brain Abscess;   Multiple Brain Abscesses;   Pyogenic Brain Abscess;   Pyogenic Brain Abscesses;   Sterile Brain Abscess;   Sterile Brain Abscesses
 primary_id: MESH:D001922
For additional species annotation, visit the Alliance of Genome Resources.


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Brain Abscess term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tlr2 toll like receptor 2 ISO RGD PMID:16239543 RGD:8552881 NCBI chrNW_004955471:8,011,710...8,019,063
Ensembl chrNW_004955471:8,014,910...8,017,258
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Cerebral Toxoplasmosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nfkb1 nuclear factor kappa B subunit 1 severity ISO RGD PMID:20156658 RGD:40902838 NCBI chrNW_004955496:5,842,734...5,950,995
Ensembl chrNW_004955496:5,842,600...5,927,885
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 13423
    disease by infectious agent 1846
      Bacterial Infections and Mycoses 850
        Central Nervous System Infections 234
          Brain Abscess 2
            Cerebral Toxoplasmosis 1
Path 2
Term Annotations click to browse term
  disease 13423
    disease of anatomical entity 13153
      Immune & Inflammatory Diseases 4237
        Inflammation 2210
          Suppuration 93
            Abscess 6
              Brain Abscess 2
                Cerebral Toxoplasmosis 1
paths to the root