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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Brain Abscess
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Accession:DOID:9008595 term browser browse the term
Definition:A circumscribed collection of purulent exudate in the brain, due to bacterial and other infections. The majority are caused by spread of infected material from a focus of suppuration elsewhere in the body, notably the PARANASAL SINUSES, middle ear (see EAR, MIDDLE); HEART (see also ENDOCARDITIS, BACTERIAL), and LUNG. Penetrating CRANIOCEREBRAL TRAUMA and NEUROSURGICAL PROCEDURES may also be associated with this condition. Clinical manifestations include HEADACHE; SEIZURES; focal neurologic deficits; and alterations of consciousness. (Adams et al., Principles of Neurology, 6th ed, pp712-6)
Synonyms:exact_synonym: Brain Abscesses;   Cerebral Abscess;   Cerebral Abscesses;   Child Brain Abscess;   Multiple Brain Abscess;   Multiple Brain Abscesses;   Pyogenic Brain Abscess;   Pyogenic Brain Abscesses;   Sterile Brain Abscess;   Sterile Brain Abscesses
 primary_id: MESH:D001922;   RDO:0005049
For additional species annotation, visit the Alliance of Genome Resources.



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Brain Abscess term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tlr2 toll-like receptor 2 ISO RGD PMID:16239543 RGD:8552881 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630
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Cerebral Toxoplasmosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nfkb1 nuclear factor kappa B subunit 1 severity ISO RGD PMID:20156658 RGD:40902838 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 17289
    disease by infectious agent 1920
      Bacterial Infections and Mycoses 796
        Central Nervous System Infections 218
          Brain Abscess 2
            Cerebral Toxoplasmosis 1
Path 2
Term Annotations click to browse term
  disease 17289
    disease of anatomical entity 16625
      Immune & Inflammatory Diseases 4036
        Inflammation 2349
          Suppuration 68
            Abscess 11
              Brain Abscess 2
                Cerebral Toxoplasmosis 1
paths to the root