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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Subretinal Fibrosis
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Accession:DOID:9008523 term browser browse the term
Definition:Fibrosis of the subretinal space resulting from hemorrhage of abnormal blood vessels, which are created by macular degeneration-associated choroidal neovascularization.


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Subretinal Fibrosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il6 interleukin 6 ISO RGD PMID:24790857 RGD:10402815 NCBI chrNW_004936549:7,015,595...7,016,246 JBrowse link
G Il6r interleukin 6 receptor treatment ISO RGD PMID:24790857 RGD:10402815 NCBI chrNW_004936580:4,055,438...4,081,876
Ensembl chrNW_004936580:4,057,771...4,081,885
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16465
    Diseases of the Aged 1178
      macular degeneration 141
        Kuhnt-Junius degeneration 28
          Subretinal Fibrosis 2
Path 2
Term Annotations click to browse term
  disease 16465
    Pathological Conditions, Signs and Symptoms 11257
      Signs and Symptoms 9333
        Neurologic Manifestations 9024
          sensory system disease 6272
            eye disease 3199
              eye degenerative disease 783
                retinal degeneration 782
                  macular degeneration 141
                    degeneration of macula and posterior pole 67
                      Kuhnt-Junius degeneration 28
                        Subretinal Fibrosis 2
paths to the root