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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Subretinal Fibrosis
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Accession:DOID:9008523 term browser browse the term
Definition:Fibrosis of the subretinal space resulting from hemorrhage of abnormal blood vessels, which are created by macular degeneration-associated choroidal neovascularization.



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Subretinal Fibrosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il6 interleukin 6 ISO RGD PMID:24790857 RGD:10402815 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Il6r interleukin 6 receptor treatment ISO RGD PMID:24790857 RGD:10402815 NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 21128
    Diseases of the Aged 1465
      macular degeneration 156
        Kuhnt-Junius degeneration 32
          Subretinal Fibrosis 2
Path 2
Term Annotations click to browse term
  disease 21128
    Pathological Conditions, Signs and Symptoms 13332
      Signs and Symptoms 10808
        Neurologic Manifestations 10040
          sensory system disease 6939
            eye disease 3475
              eye degenerative disease 848
                retinal degeneration 846
                  macular degeneration 156
                    degeneration of macula and posterior pole 73
                      Kuhnt-Junius degeneration 32
                        Subretinal Fibrosis 2
paths to the root