Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Hemorrhage
go back to main search page
Accession:DOID:9008217 term browser browse the term
Definition:Bleeding or escape of blood from a vessel.
Synonyms:exact_synonym: Bleeding;   Hemorrhages
 primary_id: MESH:D006470;   RDO:0004420


show annotations for term's descendants           Sort by:
Hemorrhage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen ISO associated with Premature Birth;DNA:polymorphism:promoter:-6G>A (human) RGD PMID:19733287 RGD:11039046 NCBI chr 8:125,283,326...125,296,445
Ensembl chr 8:125,283,273...125,296,445 		JBrowse link
G Apob apolipoprotein B ISO CTD Direct Evidence: marker/mechanism CTD PMID:31186542 NCBI chr12:8,027,629...8,066,839
Ensembl chr12:8,027,648...8,066,835 		JBrowse link
G Avpr1a arginine vasopressin receptor 1A ISO associated with Hypertension, Portal RGD PMID:14647048 RGD:2300333 NCBI chr10:122,284,404...122,289,358
Ensembl chr10:122,284,404...122,289,357 		JBrowse link
G Bdkrb2 bradykinin receptor, beta 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16514058 NCBI chr12:105,529,431...105,561,503
Ensembl chr12:105,529,485...105,561,496 		JBrowse link
G Bnip3 BCL2/adenovirus E1B interacting protein 3 ISO protein:increased expression:heart left ventricle RGD PMID:21193900 RGD:11564331 NCBI chr 7:138,492,565...138,511,235
Ensembl chr 7:138,492,565...138,511,248 		JBrowse link
G Cav1 caveolin 1, caveolae protein ISO protein:decreased expression:myocardium RGD PMID:22954805 RGD:8661809 NCBI chr 6:17,306,387...17,341,323
Ensembl chr 6:17,306,334...17,341,451 		JBrowse link
G Cryab crystallin, alpha B ISO associated with Wounds and Injuries;protein:decreased phosphorylation:heart RGD PMID:17293487 RGD:2303639 NCBI chr 9:50,657,251...50,667,936
Ensembl chr 9:50,662,625...50,667,936 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 ISO associated with Wounds, Penetrating RGD PMID:20117814 RGD:5135001 NCBI chr 5:91,039,104...91,040,980
Ensembl chr 5:91,039,100...91,040,974 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 ISO associated with Wounds, Penetrating RGD PMID:18434445 RGD:5135230 NCBI chr 5:91,051,758...91,053,797
Ensembl chr 5:91,051,730...91,053,797 		JBrowse link
G Cyp2c65 cytochrome P450, family 2, subfamily c, polypeptide 65 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18429757 PMID:18756910 PMID:20597268 PMID:25521356 PMID:27581200 NCBI chr19:39,049,450...39,082,392
Ensembl chr19:39,049,459...39,082,388 		JBrowse link
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 IMP RGD PMID:10470077 RGD:735004 NCBI chr19:40,600,810...40,730,046
Ensembl chr19:40,600,810...40,730,046 		JBrowse link
G Epha7 Eph receptor A7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30357299 NCBI chr 4:28,811,840...28,969,391
Ensembl chr 4:28,813,131...28,967,499 		JBrowse link
G F10 coagulation factor X ISO RGD PMID:8073392 RGD:11041766 NCBI chr 8:13,087,308...13,106,676
Ensembl chr 8:13,087,308...13,106,676 		JBrowse link
G F13a1 coagulation factor XIII, A1 subunit IMP RGD PMID:12529747 RGD:11041809 NCBI chr13:37,051,150...37,234,220
Ensembl chr13:37,051,152...37,234,220 		JBrowse link
G F2 coagulation factor II IMP
ISO		 CTD Direct Evidence: marker/mechanism
associated with Wounds and Injuries		 CTD
RGD		 PMID:7740448 PMID:9636195 PMID:23481505 PMID:20664909 RGD:734956, RGD:10449433, RGD:10449431 NCBI chr 2:91,442,742...91,466,799
Ensembl chr 2:91,455,665...91,466,759 		JBrowse link
G F3 coagulation factor III IMP RGD PMID:8692802 RGD:11341698 NCBI chr 3:121,517,186...121,528,701
Ensembl chr 3:121,517,186...121,528,697 		JBrowse link
G F5 coagulation factor V ISO ClinVar Annotator: match by term: Hemorrhage ClinVar PMID:25741868 PMID:28492532 PMID:34355501 NCBI chr 1:163,979,396...164,048,539
Ensembl chr 1:163,979,407...164,047,846 		JBrowse link
G F7 coagulation factor VII ISO CTD Direct Evidence: therapeutic CTD PMID:12707733 PMID:12851533 PMID:16553518 NCBI chr 8:13,075,499...13,085,809
Ensembl chr 8:13,076,034...13,085,809 		JBrowse link
G F8 coagulation factor VIII treatment ISO ClinVar Annotator: match by term: Hemorrhage ClinVar
RGD		 PMID:6438527 PMID:7728145 PMID:7984443 PMID:11442643 PMID:15921397 More... RGD:11530071 NCBI chr  X:74,213,950...74,426,342
Ensembl chr  X:74,216,321...74,426,221 		JBrowse link
G Fermt3 fermitin family member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18278053 NCBI chr19:6,976,326...6,996,837
Ensembl chr19:6,976,326...6,996,837 		JBrowse link
G Fgg fibrinogen gamma chain ISO ClinVar Annotator: match by term: Hemorrhage ClinVar PMID:25741868 NCBI chr 3:82,915,031...82,922,363
Ensembl chr 3:82,915,031...82,922,356 		JBrowse link
G Fos FBJ osteosarcoma oncogene ISO CTD Direct Evidence: marker/mechanism CTD PMID:7844257 NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047 		JBrowse link
G Gata2 GATA binding protein 2 IMP RGD PMID:22996665 RGD:11049511 NCBI chr 6:88,170,873...88,184,014
Ensembl chr 6:88,170,873...88,184,014 		JBrowse link
G Gata4 GATA binding protein 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31190750 NCBI chr14:63,436,363...63,509,161
Ensembl chr14:63,436,371...63,509,141 		JBrowse link
G Gata6 GATA binding protein 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31190750 NCBI chr18:11,052,510...11,085,636
Ensembl chr18:11,052,064...11,085,635 		JBrowse link
G Hspd1 heat shock protein 1 (chaperonin) ISO associated with Wounds and Injuries;mRNA, protein:decreased expression:heart RGD PMID:16288780 RGD:1624234 NCBI chr 1:55,116,992...55,127,402
Ensembl chr 1:55,116,994...55,127,402 		JBrowse link
G Il11 interleukin 11 ISO CTD Direct Evidence: therapeutic CTD PMID:17980069 NCBI chr 7:4,775,372...4,785,877
Ensembl chr 7:4,775,372...4,785,858 		JBrowse link
G Il1a interleukin 1 alpha ISO RGD PMID:9326742 RGD:11059516 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892 		JBrowse link
G Itgb3 integrin beta 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16153930 NCBI chr11:104,498,826...104,561,302
Ensembl chr11:104,498,826...104,561,302 		JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27581200 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838 		JBrowse link
G P2ry12 purinergic receptor P2Y, G-protein coupled 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11196645 NCBI chr 3:59,123,692...59,170,408
Ensembl chr 3:59,123,693...59,170,292 		JBrowse link
G Pi4ka phosphatidylinositol 4-kinase alpha ISO ClinVar Annotator: match by term: Hemorrhage ClinVar PMID:25741868 NCBI chr16:17,098,215...17,224,178
Ensembl chr16:17,098,215...17,224,178 		JBrowse link
G Plat plasminogen activator, tissue ISO CTD Direct Evidence: marker/mechanism CTD PMID:2514002 PMID:8082347 PMID:8427107 PMID:9199818 PMID:9266785 More... NCBI chr 8:23,247,655...23,272,864
Ensembl chr 8:23,247,743...23,272,860 		JBrowse link
G Plau plasminogen activator, urokinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:8225663 PMID:9266785 PMID:15502123 PMID:15557913 NCBI chr14:20,886,730...20,893,456
Ensembl chr14:20,886,728...20,893,453 		JBrowse link
G Podxl podocalyxin-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:22016802 NCBI chr 6:31,496,428...31,540,872
Ensembl chr 6:31,496,423...31,540,916 		JBrowse link
G Pomc pro-opiomelanocortin-alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:1267567 PMID:3014908 NCBI chr12:4,004,945...4,010,643
Ensembl chr12:4,004,951...4,010,642 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 ISO ClinVar Annotator: match by term: Hemorrhage ClinVar PMID:25741868 NCBI chr 2:36,106,758...36,142,287
Ensembl chr 2:36,120,438...36,142,284 		JBrowse link
G Ren1 renin 1 structural ISO CTD Direct Evidence: marker/mechanism CTD PMID:6991409 NCBI chr 1:133,278,412...133,288,058
Ensembl chr 1:133,278,248...133,288,063 		JBrowse link
G Serpind1 serine (or cysteine) peptidase inhibitor, clade D, member 1 ISO ClinVar Annotator: match by term: Hemorrhage ClinVar PMID:25741868 NCBI chr16:17,149,235...17,161,438
Ensembl chr16:17,149,235...17,161,439 		JBrowse link
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 treatment ISO protein:increased expression:plasma (rat)
ClinVar Annotator: match by term: Hemorrhage		 ClinVar
RGD		 PMID:25741868 PMID:26970714 PMID:9263399 RGD:11073619, RGD:11080960 NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122 		JBrowse link
G Serpinf2 serine (or cysteine) peptidase inhibitor, clade F, member 2 ISO DNA:missense mutation:cds:p.V384M (human) RGD PMID:10583218 RGD:1580303 NCBI chr11:75,322,562...75,330,327
Ensembl chr11:75,322,558...75,330,417 		JBrowse link
G Stxbp2 syntaxin binding protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30696774 NCBI chr 8:3,680,960...3,693,998
Ensembl chr 8:3,680,955...3,693,644 		JBrowse link
G Tnfrsf8 tumor necrosis factor receptor superfamily, member 8 ISO CTD Direct Evidence: therapeutic CTD PMID:29984229 NCBI chr 4:144,993,702...145,041,734
Ensembl chr 4:144,993,707...145,041,734 		JBrowse link
G Vegfa vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism CTD PMID:31068094 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295 		JBrowse link
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20597268 PMID:26445138 NCBI chr 7:127,492,235...127,494,833
Ensembl chr 7:127,485,399...127,494,626
Ensembl chr 7:127,485,399...127,494,626 		JBrowse link
G Vwf Von Willebrand factor ISO ClinVar Annotator: match by term: Hemorrhage ClinVar PMID:16985174 PMID:18230755 PMID:18344424 PMID:19506353 PMID:22995991 More... NCBI chr 6:125,529,911...125,663,642
Ensembl chr 6:125,523,737...125,663,642 		JBrowse link
Acute Subdural Hematoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epo erythropoietin treatment ISO RGD PMID:23415790 RGD:10401075 NCBI chr 5:137,481,282...137,484,078
Ensembl chr 5:137,481,282...137,531,504 		JBrowse link
G F7 coagulation factor VII ISO CTD Direct Evidence: therapeutic CTD PMID:12503044 NCBI chr 8:13,075,499...13,085,809
Ensembl chr 8:13,076,034...13,085,809 		JBrowse link
G Kcnn4 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 treatment ISO RGD PMID:15379997 RGD:329969897 NCBI chr 7:24,069,750...24,084,635
Ensembl chr 7:24,069,688...24,086,115 		JBrowse link
APP-related cerebral amyloid angiopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: AMYLOIDOSIS, CEREBROARTERIAL, APP-RELATED | ClinVar Annotator: match by term: CEREBRAL AMYLOID ANGIOPATHY, APP-RELATED, ARCTIC VARIANT | ClinVar Annotator: match by term: CEREBRAL AMYLOID ANGIOPATHY, APP-RELATED, FLEMISH VARIANT | ClinVar Annotator: match by term: CEREBRAL AMYLOID ANGIOPATHY, APP-RELATED, IOWA VARIANT | ClinVar Annotator: match by term: CEREBRAL AMYLOID ANGIOPATHY, APP-RELATED, ITALIAN VARIANT | ClinVar Annotator: match by term: Cerebral amyloid angiopathy, APP-related		 CTD
ClinVar
OMIM		 PMID:1303172 PMID:1303239 PMID:1303275 PMID:1415269 PMID:1520398 More... NCBI chr16:84,751,236...84,972,187
Ensembl chr16:84,746,573...84,970,654 		JBrowse link
autoimmune thrombocytopenic purpura term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts13 ADAM metallopeptidase with thrombospondin type 1 motif 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19260037 NCBI chr 2:26,863,363...26,899,638
Ensembl chr 2:26,863,428...26,899,640 		JBrowse link
G Alb albumin ISO RGD PMID:6683982 RGD:11036083 NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461 		JBrowse link
G Cd40 CD40 antigen ISO protein:increased expression:peripheral blood, B lymphocyte (human) RGD PMID:17654056 RGD:11344977 NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868 		JBrowse link
G Cd40lg CD40 ligand treatment ISO
IEP		 protein:increased expression:peripheral blood, T lymphocyte (human)
protein:decreased expression:serum (mouse)		 RGD PMID:17654056 PMID:22537155 PMID:18341638 PMID:16188945 RGD:11344977, RGD:11352267, RGD:11352237, RGD:11344980 NCBI chr  X:56,257,448...56,269,402
Ensembl chr  X:56,257,503...56,269,402 		JBrowse link
G Cd86 CD86 antigen treatment ISO protein:increased expression:peripheral blood mononuclear cell (human) RGD PMID:19379594 PMID:20581660 RGD:11354966, RGD:11520785 NCBI chr16:36,389,318...36,486,439
Ensembl chr16:36,424,231...36,486,443 		JBrowse link
G Dnmt3a DNA methyltransferase 3A ISO mRNA:decreased expression:mononuclear cell RGD PMID:18683034 RGD:9588662 NCBI chr12:3,851,559...3,964,442
Ensembl chr12:3,856,007...3,964,443 		JBrowse link
G Dnmt3b DNA methyltransferase 3B susceptibility ISO mRNA:decreased expression:mononuclear cell
DNA:SNP:promoter: -579G>T(human)		 RGD PMID:18683034 PMID:23000068 RGD:9588662, RGD:9589094 NCBI chr 2:153,491,332...153,529,650
Ensembl chr 2:153,491,370...153,529,650 		JBrowse link
G Fas Fas cell surface death receptor ISO protein:increased expression:serum: RGD PMID:10776692 RGD:11049162 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172 		JBrowse link
G Fcgr2b Fc receptor, IgG, low affinity IIb treatment
disease_progression		 ISO
IMP
IDA		 DNA:SNP: :p.I232T (human) RGD PMID:21131591 PMID:21045192 PMID:22257295 PMID:15566359 PMID:19549396 RGD:11040933, RGD:11344955, RGD:11344931, RGD:11344928, RGD:11344927 NCBI chr 1:170,786,186...170,804,141
Ensembl chr 1:170,786,186...170,804,116 		JBrowse link
G Fcgr3 Fc receptor, IgG, low affinity III no_association
susceptibility
treatment		 IMP
ISO		 DNA:SNP:cds:p.R131H (human) RGD PMID:20699442 PMID:23249566 PMID:22123287 PMID:21131591 RGD:11040883, RGD:11040990, RGD:11040989, RGD:11040933 NCBI chr 1:170,878,738...170,893,477
Ensembl chr 1:170,878,743...170,892,504 		JBrowse link
G Fcgr4 Fc receptor, IgG, low affinity IV treatment
susceptibility		 ISO
IGI		 DNA:SNP:cds:p.V158F(human)
DNA:SNP:exon:p.F158V (rs396991) (human)		 RGD PMID:11380443 PMID:23484707 PMID:22123287 PMID:15479722 RGD:11040776, RGD:11352255, RGD:11040989, RGD:11344926 NCBI chr 1:170,846,495...170,857,330
Ensembl chr 1:170,846,489...170,857,330 		JBrowse link
G Gp1ba glycoprotein 1b, alpha polypeptide IMP RGD PMID:16861348 RGD:10450841 NCBI chr11:70,529,928...70,534,812
Ensembl chr11:70,529,948...70,532,862 		JBrowse link
G H2-Ab1 histocompatibility 2, class II antigen A, beta 1 treatment ISO DNA:polymorphisms:cds:HLA-DQB1*0401 (human) RGD PMID:10435723 RGD:11041758 NCBI chr17:34,482,201...34,488,392
Ensembl chr17:34,476,663...34,488,393 		JBrowse link
G H2-Eb1 histocompatibility 2, class II antigen E beta treatment ISO DNA:polymorphisms:cds:HLA-DRB1*0901, HLA-DRB1*0410 (human) RGD PMID:10435723 RGD:11041758 NCBI chr17:34,524,841...34,535,648
Ensembl chr17:34,524,841...34,535,648 		JBrowse link
G Il10 interleukin 10 disease_progression ISO DNA:SNP:promoter:-627C>A (human)
DNA:SNPs, haplotypes:promoter:-1082A>G, -819C>T, -592C>A (human)		 RGD PMID:25051072 PMID:22677268 RGD:11041894, RGD:11046267 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711 		JBrowse link
G Il18 interleukin 18 ISO protein:increased expression:plasma: RGD PMID:24801815 RGD:11073600 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140 		JBrowse link
G Il1a interleukin 1 alpha ISO DNA:SNP:promoter:-899C>T (human) RGD PMID:21591983 RGD:11051966 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892 		JBrowse link
G Il1rn interleukin 1 receptor antagonist susceptibility ISO DNA:repeats:: RGD PMID:20626741 RGD:11528541 NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506 		JBrowse link
G Il2 interleukin 2 susceptibility ISO DNA:polymorphism::-330T>G(human) RGD PMID:20626741 RGD:11528541 NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108 		JBrowse link
G Il4 interleukin 4 disease_progression ISO DNA:repeat:intron RGD PMID:25051072 RGD:11041894 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496 		JBrowse link
G Itgb3 integrin beta 3 ISO
IMP		 RGD PMID:10936026 PMID:24258817 RGD:10755473, RGD:10755475 NCBI chr11:104,498,826...104,561,302
Ensembl chr11:104,498,826...104,561,302 		JBrowse link
G Mir130a microRNA 130a ISO RNA:decreased expression:PBMC RGD PMID:24801815 RGD:11073600 NCBI chr 2:84,571,459...84,571,522
Ensembl chr 2:84,571,459...84,571,522 		JBrowse link
G Mir409 microRNA 409 treatment ISO RGD PMID:23360331 RGD:10755694 NCBI chr12:109,709,592...109,709,670
Ensembl chr12:109,709,592...109,709,670 		JBrowse link
G Plat plasminogen activator, tissue ISO protein:increased expression:plasma (human) RGD PMID:2129164 RGD:11541072 NCBI chr 8:23,247,655...23,272,864
Ensembl chr 8:23,247,743...23,272,860 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) no_association ISO DNA: snp: cds: C1858T
DNA:snp:cds:c.1858C>T (rs2476601) (human)		 RGD PMID:21597364 PMID:27309885 RGD:6484673, RGD:11535019 NCBI chr 3:103,763,891...103,819,568
Ensembl chr 3:103,767,111...103,819,563 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 ISO ClinVar Annotator: match by term: Autoimmune thrombocytopenia | ClinVar Annotator: match by term: Autoimmune thrombocytopenic purpura ClinVar PMID:32853638 PMID:33087723 NCBI chr16:10,601,672...10,603,400
Ensembl chr16:10,600,104...10,603,400 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 disease_progression ISO mRNA:increased expression: :
protein:decreased expression:plasma:		 RGD PMID:11886393 PMID:24763013 PMID:24801815 RGD:11073598, RGD:11073603, RGD:11073600 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502 		JBrowse link
Basal Ganglia Hemorrhage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsn gelsolin severity ISO protein:decreased expression:blood plasma (human) RGD PMID:23142649 RGD:329333032 NCBI chr 2:35,146,371...35,197,914
Ensembl chr 2:35,146,392...35,197,904 		JBrowse link
benign familial hematuria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col4a3 collagen, type IV, alpha 3 ISO ClinVar Annotator: match by term: Benign familial hematuria | ClinVar Annotator: match by term: Microscopic hematuria ClinVar
RGD		 PMID:2557550 PMID:9536098 PMID:11134255 PMID:11961012 PMID:12028435 More... RGD:7242047 NCBI chr 1:82,564,647...82,699,778
Ensembl chr 1:82,564,642...82,699,780 		JBrowse link
G Col4a4 collagen, type IV, alpha 4 ISO ClinVar Annotator: match by term: Benign familial hematuria | ClinVar Annotator: match by term: Microscopic hematuria
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
RGD		 PMID:8787673 PMID:9536098 PMID:9792860 PMID:11961012 PMID:12325029 More... RGD:7242047 NCBI chr 1:82,426,140...82,564,570
Ensembl chr 1:82,426,144...82,564,570 		JBrowse link
G Col4a5 collagen, type IV, alpha 5 ISO ClinVar Annotator: match by term: Familial hematuria | ClinVar Annotator: match by term: Microscopic hematuria ClinVar PMID:25741868 NCBI chr  X:140,258,367...140,472,232
Ensembl chr  X:140,258,381...140,472,230 		JBrowse link
G Lama5 laminin, alpha 5 ISO ClinVar Annotator: match by term: Familial hematuria ClinVar PMID:25741868 PMID:28492532 PMID:29764427 NCBI chr 2:179,818,166...179,867,652
Ensembl chr 2:179,818,166...179,867,652 		JBrowse link
G Myo1e myosin IE ISO ClinVar Annotator: match by term: Microscopic hematuria ClinVar PMID:24033266 PMID:25741868 PMID:28492532 NCBI chr 9:70,114,632...70,307,349
Ensembl chr 9:70,114,632...70,307,048 		JBrowse link
G Plce1 phospholipase C, epsilon 1 ISO ClinVar Annotator: match by term: Microscopic hematuria ClinVar PMID:25741868 NCBI chr19:38,469,438...38,773,549
Ensembl chr19:38,469,557...38,773,474 		JBrowse link
G Wt1 WT1 transcription factor ISO ClinVar Annotator: match by term: Microscopic hematuria ClinVar PMID:9108089 PMID:24033266 PMID:24728327 PMID:25741868 PMID:28492532 NCBI chr 2:104,956,874...105,003,959
Ensembl chr 2:104,956,874...105,003,961 		JBrowse link
Benign Familial Hematuria 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col4a4 collagen, type IV, alpha 4 ISO ClinVar Annotator: match by term: COL4A4-related condition OMIM
ClinVar		 PMID:9536098 PMID:9792860 PMID:12325029 PMID:12631110 PMID:14871398 More... NCBI chr 1:82,426,140...82,564,570
Ensembl chr 1:82,426,144...82,564,570 		JBrowse link
Benign Familial Hematuria 2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col4a3 collagen, type IV, alpha 3 ISO OMIM NCBI chr 1:82,564,647...82,699,778
Ensembl chr 1:82,564,642...82,699,780 		JBrowse link
brain small vessel disease 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col4a1 collagen, type IV, alpha 1 IAGP
ISO		 OMIM:607595
ClinVar Annotator: match by term: BRAIN SMALL VESSEL DISEASE 1 WITH OR WITHOUT OCULAR ANOMALIES | ClinVar Annotator: match by term: Brain small vessel disease 1 with or without ocular anomalies | ClinVar Annotator: match by term: Brain small vessel disease with hemorrhage
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Brain small vessel disease 1 with or without ocular anomalies | ClinVar Annotator: match by term: GOULD SYNDROME 1 | ClinVar Annotator: match by term: RETINAL ARTERIOLAR TORTUOSITY, INFANTILE HEMIPARESIS, AND LEUKOENCEPHALOPATHY, AUTOSOMAL DOMINANT		 MouseDO
ClinVar
OMIM
CTD		 PMID:906807 PMID:2211826 PMID:3691802 PMID:6428250 PMID:7257746 More... NCBI chr 8:11,248,423...11,362,889
Ensembl chr 8:11,248,423...11,362,826 		JBrowse link
G Col4a2 collagen, type IV, alpha 2 ISO ClinVar Annotator: match by term: Brain small vessel disease with hemorrhage ClinVar PMID:25741868 PMID:26467025 PMID:28492532 NCBI chr 8:11,362,878...11,499,287
Ensembl chr 8:11,362,805...11,499,287 		JBrowse link
G Kat6b K(lysine) acetyltransferase 6B ISO ClinVar Annotator: match by term: Brain small vessel disease with hemorrhage ClinVar PMID:25741868 NCBI chr14:21,549,284...21,722,546
Ensembl chr14:21,531,502...21,722,546 		JBrowse link
Cerebral Hemorrhage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Hemorrhage, intracerebral, susceptibility to | ClinVar Annotator: match by term: Stroke, hemorrhagic, susceptibility to		 CTD
ClinVar		 PMID:1313972 PMID:1319114 PMID:1328889 PMID:1386652 PMID:1976655 More... NCBI chr11:105,858,774...105,880,790
Ensembl chr11:105,858,771...105,880,790 		JBrowse link
G Anxa1 annexin A1 ISO mRNA:increased expression:brain RGD PMID:16034371 RGD:2306905 NCBI chr19:20,350,798...20,368,035
Ensembl chr19:20,350,792...20,368,308 		JBrowse link
G Apex1 apurinic/apyrimidinic endonuclease 1 ISO RGD PMID:15344903 RGD:2315676 NCBI chr14:51,162,406...51,164,645
Ensembl chr14:51,162,425...51,164,596 		JBrowse link
G Apoe apolipoprotein E ISO DNA:missense mutations, haplotype:cds:p.C112R (rs7412) (human) RGD PMID:19251191 RGD:6904207 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113 		JBrowse link
G Aqp4 aquaporin 4 ISO RGD PMID:25545558 RGD:11541062 NCBI chr18:15,522,451...15,544,039
Ensembl chr18:15,522,553...15,544,039 		JBrowse link
G Bax BCL2-associated X protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:12721362 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322 		JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12721362 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004 		JBrowse link
G Bcl2l1 BCL2-like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12721362 NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648 		JBrowse link
G Bdnf brain derived neurotrophic factor ISO RGD PMID:20818776 RGD:4891129 NCBI chr 2:109,505,045...109,557,388
Ensembl chr 2:109,505,045...109,557,352 		JBrowse link
G Becn1 beclin 1, autophagy related ISO protein:increased expression:basal ganglion RGD PMID:23884876 RGD:11561935 NCBI chr11:101,179,084...101,193,112
Ensembl chr11:101,176,778...101,193,112 		JBrowse link
G Bnip3l BCL2/adenovirus E1B interacting protein 3-like ISO RGD PMID:23771482 RGD:7483577 NCBI chr14:67,222,688...67,246,580
Ensembl chr14:67,222,688...67,246,326 		JBrowse link
G C3 complement component 3 ISO RGD PMID:17114852 RGD:5129540 NCBI chr17:57,510,967...57,535,136
Ensembl chr17:57,510,970...57,535,136 		JBrowse link
G Casp12 caspase 12 treatment ISO RGD PMID:28544790 RGD:13782167 NCBI chr 9:5,345,419...5,373,034
Ensembl chr 9:5,345,430...5,373,032 		JBrowse link
G Casp3 caspase 3 ameliorates
treatment		 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:17971790 PMID:31376096 PMID:28096675 RGD:329337378, RGD:13782306 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724 		JBrowse link
G Casp8 caspase 8 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:17971790 PMID:28096675 RGD:13782306 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662 		JBrowse link
G Casp9 caspase 9 treatment ISO RGD PMID:28096675 RGD:13782306 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287 		JBrowse link
G Cd14 CD14 antigen ISO mRNA:increased expression:lung, intestine: RGD PMID:19534684 RGD:7185660 NCBI chr18:36,858,117...36,859,868
Ensembl chr18:36,858,120...36,859,851 		JBrowse link
G Cd36 CD36 molecule IDA RGD PMID:19064796 RGD:6893504 NCBI chr 5:17,986,680...18,093,828
Ensembl chr 5:17,986,688...18,093,799 		JBrowse link
G Cfh complement component factor h severity ISO RGD PMID:21871809 RGD:5684553 NCBI chr 1:140,013,593...140,111,149
Ensembl chr 1:140,012,446...140,111,502 		JBrowse link
G Cntf ciliary neurotrophic factor ISO CTD Direct Evidence: therapeutic CTD PMID:11701153 NCBI chr19:12,740,892...12,742,996
Ensembl chr19:12,741,024...12,742,996 		JBrowse link
G Col4a1 collagen, type IV, alpha 1 IAGP
ISO		 ClinVar Annotator: match by term: Hemorrhage, intracerebral, susceptibility to | ClinVar Annotator: match by term: Stroke, hemorrhagic, susceptibility to
CTD Direct Evidence: marker/mechanism		 ClinVar
OMIM
CTD
RGD		 PMID:3691802 PMID:7695699 PMID:8218237 PMID:9016532 PMID:9536098 More... RGD:1581204 NCBI chr 8:11,248,423...11,362,889
Ensembl chr 8:11,248,423...11,362,826 		JBrowse link
G Col4a2 collagen, type IV, alpha 2 susceptibility ISO DNA:SNPs::
ClinVar Annotator: match by term: COL4A2-Related Disorder | ClinVar Annotator: match by term: Hemorrhage, intracerebral, susceptibility to
CTD Direct Evidence: marker/mechanism		 ClinVar
OMIM
CTD
RGD		 PMID:22209247 PMID:22914737 PMID:24390199 PMID:24646874 PMID:25653287 More... RGD:13450933 NCBI chr 8:11,362,878...11,499,287
Ensembl chr 8:11,362,805...11,499,287 		JBrowse link
G Csf3 colony stimulating factor 3 (granulocyte) treatment ISO RGD PMID:19169816 RGD:11039433 NCBI chr11:98,591,287...98,594,457
Ensembl chr11:98,592,089...98,594,455 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 treatment ISO RGD PMID:24955809 RGD:11352686 NCBI chr 1:128,515,936...128,520,036
Ensembl chr 1:128,515,936...128,520,030 		JBrowse link
G Dag1 dystroglycan 1 ISO RGD PMID:25545558 RGD:11541062 NCBI chr 9:108,082,060...108,141,176
Ensembl chr 9:108,081,833...108,141,157 		JBrowse link
G Dcx doublecortin ISO protein:increased expression:dentate gyrus RGD PMID:24144742 RGD:12904766 NCBI chr  X:142,638,838...142,716,392
Ensembl chr  X:142,638,838...142,716,307 		JBrowse link
G F11 coagulation factor XI ISO ClinVar Annotator: match by term: Cerebral hemorrhage ClinVar PMID:23929304 PMID:27067486 PMID:28492532 PMID:34776502 NCBI chr 8:45,693,696...45,715,092
Ensembl chr 8:45,694,211...45,715,068 		JBrowse link
G F13a1 coagulation factor XIII, A1 subunit ISO RGD PMID:9550516 RGD:1581027 NCBI chr13:37,051,150...37,234,220
Ensembl chr13:37,051,152...37,234,220 		JBrowse link
G F2 coagulation factor II severity ISO protein:increased expression:plasma RGD PMID:21244583 RGD:5147770 NCBI chr 2:91,442,742...91,466,799
Ensembl chr 2:91,455,665...91,466,759 		JBrowse link
G F7 coagulation factor VII treatment ISO human protein in a rat model
CTD Direct Evidence: therapeutic		 CTD
RGD		 PMID:16671457 PMID:21127298 PMID:16671457 RGD:11049545 NCBI chr 8:13,075,499...13,085,809
Ensembl chr 8:13,076,034...13,085,809 		JBrowse link
G Flt1 FMS-like tyrosine kinase 1 ISO mRNA:increased expression:brain:
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:17888890 PMID:17888890 RGD:10402152 NCBI chr 5:147,498,414...147,663,419
Ensembl chr 5:147,498,414...147,662,821 		JBrowse link
G Fto FTO alpha-ketoglutarate dependent dioxygenase IEP protein:increased expression:thalamic complex RGD PMID:34102854 RGD:329812008 NCBI chr 8:92,039,995...92,395,061
Ensembl chr 8:92,040,153...92,395,067 		JBrowse link
G Gm32234 predicted gene, 32234 ISO ClinVar Annotator: match by term: Hemorrhage, intracerebral, susceptibility to ClinVar PMID:28492532 NCBI chr10:40,330,078...40,342,623 JBrowse link
G Gp6 glycoprotein 6 platelet ameliorates IMP associated with hypertension RGD PMID:33556561 RGD:401794565 NCBI chr 7:4,365,852...4,400,849
Ensembl chr 7:4,366,964...4,400,743 		JBrowse link
G Hmox1 heme oxygenase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12401953 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217 		JBrowse link
G Hmox2 heme oxygenase 2 ISO CTD Direct Evidence: therapeutic CTD PMID:16459095 NCBI chr16:4,544,225...4,584,606
Ensembl chr16:4,544,225...4,584,606 		JBrowse link
G Hp haptoglobin treatment IMP
ISO		 RGD PMID:20016097 PMID:20016097 RGD:11041810, RGD:11041810 NCBI chr 8:110,301,760...110,305,804
Ensembl chr 8:110,301,760...110,305,804 		JBrowse link
G Ifnb1 interferon beta 1, fibroblast exacerbates IMP RGD PMID:29301581 RGD:401854231 NCBI chr 4:88,440,253...88,441,083
Ensembl chr 4:88,440,262...88,441,011 		JBrowse link
G Il1b interleukin 1 beta ameliorates ISO RGD PMID:31376096 RGD:329337378 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059 		JBrowse link
G Il1rn interleukin 1 receptor antagonist treatment ISO mRNA:increased expression:striatum (rat)
human gene in a rat model		 RGD PMID:22707991 PMID:14753487 RGD:6997504, RGD:8551833 NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506 		JBrowse link
G Il6 interleukin 6 ameliorates ISO RGD PMID:31376096 RGD:329337378 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Itga2b integrin alpha 2b ISO CTD Direct Evidence: marker/mechanism CTD PMID:9445356 NCBI chr11:102,344,134...102,360,570
Ensembl chr11:102,344,123...102,360,948 		JBrowse link
G Itgav integrin alpha V ISO CTD Direct Evidence: marker/mechanism CTD PMID:9445356 NCBI chr 2:83,554,796...83,637,261
Ensembl chr 2:83,554,741...83,637,260 		JBrowse link
G Itgb2 integrin beta 2 IMP RGD PMID:18615643 RGD:6482197 NCBI chr10:77,366,164...77,401,542
Ensembl chr10:77,366,086...77,401,542 		JBrowse link
G Itgb3 integrin beta 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:9445356 NCBI chr11:104,498,826...104,561,302
Ensembl chr11:104,498,826...104,561,302 		JBrowse link
G Kat6b K(lysine) acetyltransferase 6B ISO ClinVar Annotator: match by term: Stroke, hemorrhagic, susceptibility to ClinVar PMID:25741868 NCBI chr14:21,549,284...21,722,546
Ensembl chr14:21,531,502...21,722,546 		JBrowse link
G Kdr kinase insert domain protein receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:17888890 NCBI chr 5:76,093,487...76,139,880
Ensembl chr 5:76,093,487...76,139,118 		JBrowse link
G Lcn2 lipocalin 2 ISO RGD PMID:23416150 RGD:126790480 NCBI chr 2:32,274,649...32,277,751
Ensembl chr 2:32,274,645...32,278,264 		JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha ISO RGD PMID:23884876 RGD:11561935 NCBI chr 2:155,118,284...155,119,993
Ensembl chr 2:155,118,217...155,119,993 		JBrowse link
G Mir126a microRNA 126a ameliorates ISO RGD PMID:32160957 RGD:401851064 NCBI chr 2:26,481,369...26,481,441
Ensembl chr 2:26,481,369...26,481,441 		JBrowse link
G Mir140 microRNA 140 ameliorates ISO RGD PMID:31376096 RGD:329337378 NCBI chr 8:108,277,876...108,277,945
Ensembl chr 8:108,277,876...108,277,945 		JBrowse link
G Mir152 microRNA 152 treatment ISO RGD PMID:31982825 RGD:21066340 NCBI chr11:96,741,219...96,741,291
Ensembl chr11:96,741,219...96,741,291 		JBrowse link
G Mir23a microRNA 23a ameliorates ISO RNA:increased expression:serum RGD PMID:33403590 PMID:29771433 RGD:155882539, RGD:155882557 NCBI chr 8:84,935,147...84,935,221
Ensembl chr 8:84,935,147...84,935,221 		JBrowse link
G Mmp12 matrix metallopeptidase 12 IAGP RGD PMID:15654856 RGD:1582358 NCBI chr 9:7,344,397...7,360,461
Ensembl chr 9:7,344,381...7,369,499 		JBrowse link
G Mmp2 matrix metallopeptidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10698078 NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048 		JBrowse link
G Mmp3 matrix metallopeptidase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17971790 NCBI chr 9:7,445,845...7,455,975
Ensembl chr 9:7,445,822...7,455,975 		JBrowse link
G Mmp9 matrix metallopeptidase 9 IAGP
ISO		 CTD Direct Evidence: marker/mechanism|therapeutic CTD
RGD		 PMID:14630814 PMID:15488484 PMID:15529013 PMID:16190367 PMID:19095969 More... RGD:1582637 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770 		JBrowse link
G Mt1 metallothionein 1 ISO mRNA:increased expression:cerebral cortex, striatum (rat) RGD PMID:16034371 RGD:2306905 NCBI chr 8:94,905,214...94,906,955
Ensembl chr 8:94,905,710...94,906,955 		JBrowse link
G Mt2 metallothionein 2 ISO mRNA:increased expression:cerebral cortex, striatum (rat) RGD PMID:16034371 RGD:2306905 NCBI chr 8:94,899,246...94,900,195
Ensembl chr 8:94,899,292...94,900,196 		JBrowse link
G Mtor mechanistic target of rapamycin kinase treatment ISO RGD PMID:24602288 RGD:10041041 NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140 		JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 ISO protein:increased activity:striatum RGD PMID:17250675 RGD:2302394 NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308 		JBrowse link
G Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100 ISO protein:increased activity:striatum RGD PMID:17250675 RGD:2302394 NCBI chr19:46,285,478...46,300,839
Ensembl chr19:46,292,759...46,300,824 		JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha ISO protein:increased phosphorylation:brain RGD PMID:20150961 RGD:10413872 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432 		JBrowse link
G Nppb natriuretic peptide type B ISO CTD Direct Evidence: therapeutic CTD PMID:19803787 NCBI chr 4:148,070,264...148,071,662
Ensembl chr 4:148,070,245...148,071,662 		JBrowse link
G Npy neuropeptide Y ISO protein:increased expression:plasma (rat) RGD PMID:15068713 RGD:1580182 NCBI chr 6:49,799,690...49,806,487
Ensembl chr 6:49,799,690...49,806,487 		JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 treatment ISO RGD PMID:29050310 RGD:13442476 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838 		JBrowse link
G Plat plasminogen activator, tissue treatment
severity		 ISO
IMP		 human protein in a rat model
CTD Direct Evidence: marker/mechanism
associated with Brain Injuries		 CTD
RGD		 PMID:1430592 PMID:1579960 PMID:1899364 PMID:7477192 PMID:7723950 More... RGD:11537477, RGD:11541064 NCBI chr 8:23,247,655...23,272,864
Ensembl chr 8:23,247,743...23,272,860 		JBrowse link
G Plau plasminogen activator, urokinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:1265806 PMID:8025938 PMID:9731615 PMID:15181847 PMID:17702958 NCBI chr14:20,886,730...20,893,456
Ensembl chr14:20,886,728...20,893,453 		JBrowse link
G Plod3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 ISO ClinVar Annotator: match by term: Hemorrhage, intracerebral, susceptibility to ClinVar PMID:25741868 PMID:28492532 NCBI chr 5:137,015,873...137,025,500
Ensembl chr 5:137,015,873...137,025,502 		JBrowse link
G Pomc pro-opiomelanocortin-alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:6254450 NCBI chr12:4,004,945...4,010,643
Ensembl chr12:4,004,951...4,010,642 		JBrowse link
G Psen1 presenilin 1 IAGP RGD PMID:16079160 RGD:1580694 NCBI chr12:83,734,926...83,781,869
Ensembl chr12:83,734,926...83,781,973 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO
IEP		 protein:increased expression:neuron, astrocyte, blood vessel RGD PMID:21385433 PMID:21385433 RGD:5508223, RGD:5508223 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978 		JBrowse link
G Rad21 RAD21 cohesin complex component severity ISO RGD PMID:36538854 RGD:243065265 NCBI chr15:51,826,000...51,856,934
Ensembl chr15:51,825,636...51,855,143 		JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) ISO protein:increased activity:striatum RGD PMID:17250675 RGD:2302394 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158 		JBrowse link
G Relb avian reticuloendotheliosis viral (v-rel) oncogene related B ISO mRNA, protein:increased expression, increased activity:striatum RGD PMID:17250675 RGD:2302394 NCBI chr 7:19,340,142...19,363,352
Ensembl chr 7:19,340,142...19,363,363 		JBrowse link
G S100b S100 protein, beta polypeptide, neural disease_progression ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:19027832 PMID:19505208 RGD:5508801 NCBI chr10:76,089,670...76,097,153
Ensembl chr10:76,089,687...76,096,993 		JBrowse link
G Serpina3b serine (or cysteine) peptidase inhibitor, clade A, member 3B ISO RGD PMID:12126519 RGD:1580109 NCBI chr12:104,094,245...104,105,805
Ensembl chr12:104,094,255...104,105,804 		JBrowse link
G Serpinc1 serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:6636041 NCBI chr 1:160,806,153...160,830,113
Ensembl chr 1:160,806,155...160,833,433 		JBrowse link
G Slc24a1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 ISO mRNA, protein:decreased expression:cerebrum RGD PMID:23564126 RGD:9685494 NCBI chr 9:64,830,143...64,858,902
Ensembl chr 9:64,830,143...64,858,889 		JBrowse link
G Slc8b1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 ISO RGD PMID:23564126 RGD:9685494 NCBI chr 5:120,649,233...120,672,089
Ensembl chr 5:120,649,233...120,672,089 		JBrowse link
G Spp1 secreted phosphoprotein 1 ISO CTD Direct Evidence: therapeutic CTD PMID:20440599 NCBI chr 5:104,582,977...104,588,919
Ensembl chr 5:104,582,984...104,588,916 		JBrowse link
G Sqstm1 sequestosome 1 ISO protein:decreased expression:basal ganglion RGD PMID:23884876 RGD:11561935 NCBI chr11:50,090,979...50,105,303
Ensembl chr11:50,090,193...50,101,654 		JBrowse link
G Thbs1 thrombospondin 1 ISO RGD PMID:20136391 RGD:2317938 NCBI chr 2:117,942,357...117,957,614
Ensembl chr 2:117,942,357...117,957,614 		JBrowse link
G Thbs2 thrombospondin 2 ISO RGD PMID:20136391 RGD:2317938 NCBI chr17:14,885,762...14,914,524
Ensembl chr17:14,885,762...14,914,497 		JBrowse link
G Tnf tumor necrosis factor ameliorates ISO RGD PMID:31376096 RGD:329337378 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
G Vegfa vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism CTD PMID:17888890 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295 		JBrowse link
Drug-Induced Immune Thrombocytopenia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP-binding cassette, sub-family member 2 susceptibility ISO associated with Carcinoma, Non-Small-Cell Lung;DNA:SNP, haplotype:promoter,cds: 3972C>T, -24C>T(human) RGD PMID:20943283 RGD:11080978 NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179 		JBrowse link
G Dpyd dihydropyrimidine dehydrogenase treatment ISO associated with Neoplasms;DNA:SNP:intron:IVS14+1G>A (human)
associated with Stomach Neoplasms		 RGD PMID:19473056 PMID:23064955 RGD:11098817, RGD:11251740 NCBI chr 3:118,355,758...119,226,573
Ensembl chr 3:118,355,778...119,226,573 		JBrowse link
G Gstm1 glutathione S-transferase, mu 1 susceptibility
treatment		 ISO associated with Ovarian Neoplasms;DNA:deletion: : (human)
associated with diffuse large B-cell lymphoma; DNA:deletion:cds:		 RGD PMID:19786980 PMID:20303013 RGD:5688741, RGD:10450835 NCBI chr 3:107,919,566...107,925,289
Ensembl chr 3:107,919,571...107,925,289 		JBrowse link
G Gstt1 glutathione S-transferase, theta 1 treatment ISO associated with diffuse large B-cell lymphoma; DNA:deletion:cds: RGD PMID:20303013 RGD:10450835 NCBI chr10:75,619,647...75,634,418
Ensembl chr10:75,619,647...75,634,418 		JBrowse link
G Il1a interleukin 1 alpha treatment ISO associated with Carcinoma, Non-Small-Cell Lung
associated with Ovarian Neoplasms		 RGD PMID:7666093 PMID:8151314 RGD:11051963, RGD:11051964 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892 		JBrowse link
G Il1b interleukin 1 beta treatment ISO associated with Glioblastoma; RGD PMID:1331350 RGD:10450883 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059 		JBrowse link
G Pecam1 platelet/endothelial cell adhesion molecule 1 severity ISO
IMP		 RGD PMID:10942385 PMID:17234740 RGD:11541093, RGD:11541120 NCBI chr11:106,545,039...106,606,107
Ensembl chr11:106,545,043...106,641,454 		JBrowse link
G Pf4 platelet factor 4 treatment ISO RGD PMID:31863655 RGD:329901923 NCBI chr 5:90,920,362...90,921,242
Ensembl chr 5:90,920,294...90,921,242 		JBrowse link
Epistaxis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvrl1 activin A receptor, type II-like 1 ISO ClinVar Annotator: match by term: Epistaxis ClinVar PMID:11484689 PMID:15687131 PMID:16540754 PMID:17786384 PMID:18159113 More... NCBI chr15:101,026,403...101,043,217
Ensembl chr15:101,026,403...101,043,217 		JBrowse link
G Eng endoglin IMP
ISO		 ClinVar Annotator: match by term: Spontaneous, recurrent epistaxis ClinVar
RGD		 PMID:15879500 PMID:16542389 PMID:28492532 PMID:30251589 PMID:10562296 RGD:11041563 NCBI chr 2:32,536,607...32,572,681
Ensembl chr 2:32,536,607...32,572,681 		JBrowse link
G Gstt1 glutathione S-transferase, theta 1 susceptibility ISO DNA:deletion:cds (human) RGD PMID:18066575 RGD:7794809 NCBI chr10:75,619,647...75,634,418
Ensembl chr10:75,619,647...75,634,418 		JBrowse link
Gastrointestinal Hemorrhage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC, WNT signaling pathway regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:24430131 NCBI chr18:34,353,350...34,455,243
Ensembl chr18:34,353,977...34,455,605 		JBrowse link
G Avp arginine vasopressin ISO CTD Direct Evidence: therapeutic CTD PMID:6983645 NCBI chr 2:130,422,540...130,424,508
Ensembl chr 2:130,422,540...130,424,474 		JBrowse link
G Bax BCL2-associated X protein treatment ISO RGD PMID:24058648 RGD:10058975 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322 		JBrowse link
G Chek2 checkpoint kinase 2 ISO ClinVar Annotator: match by term: Hematochezia ClinVar PMID:10617473 PMID:11053450 PMID:11479205 PMID:11719428 PMID:11967536 More... NCBI chr 5:110,987,668...111,022,006
Ensembl chr 5:110,987,845...111,022,011 		JBrowse link
G Csf2 colony stimulating factor 2 (granulocyte-macrophage) ISO CTD Direct Evidence: marker/mechanism CTD PMID:11732872 NCBI chr11:54,138,096...54,140,725
Ensembl chr11:54,138,097...54,140,493 		JBrowse link
G Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 susceptibility ISO associated with Gastrointestinal Diseases; DNA:polymorphisms: : RGD PMID:25605208 RGD:124713539 NCBI chr19:39,379,109...39,451,519
Ensembl chr19:39,378,000...39,451,519 		JBrowse link
G Flna filamin, alpha ISO ClinVar Annotator: match by term: Hematochezia ClinVar PMID:25741868 PMID:28492532 PMID:30755392 NCBI chr  X:73,267,067...73,293,787
Ensembl chr  X:73,267,067...73,293,426 		JBrowse link
G Ltf lactotransferrin ISO CTD Direct Evidence: therapeutic CTD PMID:15651117 NCBI chr 9:110,848,360...110,871,834
Ensembl chr 9:110,848,339...110,871,835 		JBrowse link
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 ISO ClinVar Annotator: match by term: Gastrointestinal hemorrhage ClinVar PMID:25741868 NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122 		JBrowse link
G Vwf Von Willebrand factor ISO protein:increased expression: : RGD PMID:9790822 RGD:11080743 NCBI chr 6:125,529,911...125,663,642
Ensembl chr 6:125,523,737...125,663,642 		JBrowse link
hemarthrosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl2 C-C motif chemokine ligand 2 IEP associated with Hemophilia A;protein:increased expression:synovial fluid (mouse) RGD PMID:19444976 RGD:11528538 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279 		JBrowse link
G F8 coagulation factor VIII treatment ISO RGD PMID:31899798 RGD:150520060 NCBI chr  X:74,213,950...74,426,342
Ensembl chr  X:74,216,321...74,426,221 		JBrowse link
G Il6 interleukin 6 treatment IDA associated with Hemophilia A RGD PMID:23413986 RGD:11060150 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
Hematoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd36 CD36 molecule treatment ISO
IEP		 associated with Cerebral Hemorrhage RGD PMID:24808360 PMID:24808360 RGD:11040930, RGD:11040930 NCBI chr 5:17,986,680...18,093,828
Ensembl chr 5:17,986,688...18,093,799 		JBrowse link
G S100b S100 protein, beta polypeptide, neural ISO associated with Stroke;protein:increased expression:serum
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:19027832 PMID:19147496 RGD:5508832 NCBI chr10:76,089,670...76,097,153
Ensembl chr10:76,089,687...76,096,993 		JBrowse link
Hematuria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aspg asparaginase ISO CTD Direct Evidence: marker/mechanism CTD PMID:2187653 NCBI chr12:112,073,117...112,094,007
Ensembl chr12:112,073,113...112,093,993 		JBrowse link
G C3 complement component 3 ISO protein:increased expression:renal arteriole: RGD PMID:10955930 RGD:7183083 NCBI chr17:57,510,967...57,535,136
Ensembl chr17:57,510,970...57,535,136 		JBrowse link
G Col4a3 collagen, type IV, alpha 3 ISO ClinVar Annotator: match by term: Hematuria | ClinVar Annotator: match by term: Macroscopic hematuria ClinVar
RGD		 PMID:8956999 PMID:16199547 PMID:24052634 PMID:24854265 PMID:25307543 More... RGD:7242047 NCBI chr 1:82,564,647...82,699,778
Ensembl chr 1:82,564,642...82,699,780 		JBrowse link
G Col4a4 collagen, type IV, alpha 4 ISO ClinVar Annotator: match by term: Hematuria ClinVar
RGD		 PMID:24052634 PMID:24854265 PMID:25741868 PMID:26809805 PMID:28492532 More... RGD:7242047 NCBI chr 1:82,426,140...82,564,570
Ensembl chr 1:82,426,144...82,564,570 		JBrowse link
G Col4a5 collagen, type IV, alpha 5 onset ISO ClinVar Annotator: match by term: Hematuria ClinVar
RGD		 PMID:9150741 PMID:11223851 PMID:12028435 PMID:12796257 PMID:14514738 More... RGD:329845598 NCBI chr  X:140,258,367...140,472,232
Ensembl chr  X:140,258,381...140,472,230 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29027484 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107 		JBrowse link
G F7 coagulation factor VII ISO CTD Direct Evidence: therapeutic CTD PMID:17133240 NCBI chr 8:13,075,499...13,085,809
Ensembl chr 8:13,076,034...13,085,809 		JBrowse link
G Fos FBJ osteosarcoma oncogene treatment ISO RGD PMID:22634839 RGD:7242178 NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047 		JBrowse link
G Lama5 laminin, alpha 5 ISO ClinVar Annotator: match by term: Macroscopic hematuria ClinVar PMID:25741868 NCBI chr 2:179,818,166...179,867,652
Ensembl chr 2:179,818,166...179,867,652 		JBrowse link
G Lmx1b LIM homeobox transcription factor 1 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:19147669 NCBI chr 2:33,450,977...33,531,219
Ensembl chr 2:33,450,977...33,530,620 		JBrowse link
G Plau plasminogen activator, urokinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:8225663 NCBI chr14:20,886,730...20,893,456
Ensembl chr14:20,886,728...20,893,453 		JBrowse link
G Pomc pro-opiomelanocortin-alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:1267567 PMID:1324751 NCBI chr12:4,004,945...4,010,643
Ensembl chr12:4,004,951...4,010,642 		JBrowse link
Hemophilic Arthropathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F8 coagulation factor VIII treatment ISO RGD PMID:27060449 RGD:150520059 NCBI chr  X:74,213,950...74,426,342
Ensembl chr  X:74,216,321...74,426,221 		JBrowse link
Hemorrhagic Shock term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adm adrenomedullin treatment ISO RGD PMID:18403050 PMID:15973109 RGD:7364987, RGD:7364990 NCBI chr 7:110,226,864...110,229,027
Ensembl chr 7:110,226,868...110,229,027 		JBrowse link
G Aldh1a7 aldehyde dehydrogenase family 1, subfamily A7 severity ISO RGD PMID:23810746 PMID:21643955 RGD:14367884, RGD:14367885 NCBI chr19:20,670,318...20,704,920
Ensembl chr19:20,670,317...20,704,926 		JBrowse link
G Angpt1 angiopoietin 1 ISO RGD PMID:18344375 RGD:2316067 NCBI chr15:42,288,063...42,540,373
Ensembl chr15:42,288,119...42,540,373 		JBrowse link
G Arg2 arginase type II ISO protein:increased expression:aorta (rat) RGD PMID:20699748 RGD:4143274 NCBI chr12:79,177,562...79,203,075
Ensembl chr12:79,177,551...79,203,075 		JBrowse link
G Bad BCL2-associated agonist of cell death ISO protein:decreased serine phosphorylation:lung RGD PMID:15345971 RGD:2292699 NCBI chr19:6,919,229...6,929,273
Ensembl chr19:6,919,229...6,929,267 		JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 ISO mRNA:increased expression:intestine RGD PMID:17693937 RGD:2293072 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004 		JBrowse link
G Bcl2l1 BCL2-like 1 ISO protein:increased expression:liver, mitochondrion RGD PMID:17224795 RGD:1643525 NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648 		JBrowse link
G Casp3 caspase 3 ISO associated with Brain Injuries, Traumatic RGD PMID:29061477 RGD:13782298 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724 		JBrowse link
G Casp8 caspase 8 ISO associated with Brain Injuries, Traumatic RGD PMID:29061477 RGD:13782298 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662 		JBrowse link
G Cfh complement component factor h treatment ISO RGD PMID:18403050 PMID:18496585 PMID:15973109 RGD:7364987, RGD:11041173, RGD:7364990 NCBI chr 1:140,013,593...140,111,149
Ensembl chr 1:140,012,446...140,111,502 		JBrowse link
G Cnr1 cannabinoid receptor 1 ISO mRNA, protein:increased expression:aorta, mesenteric artery RGD PMID:19493421 RGD:2314664 NCBI chr 4:33,923,171...33,948,831
Ensembl chr 4:33,924,593...33,948,831 		JBrowse link
G Cul5 cullin 5 ISO mRNA:altered expression:brain RGD PMID:12635525 RGD:2301433 NCBI chr 9:53,525,881...53,578,807
Ensembl chr 9:53,525,882...53,581,314 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:21192278 PMID:21168948 RGD:5128673 NCBI chr 5:91,039,104...91,040,980
Ensembl chr 5:91,039,100...91,040,974 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21192278 NCBI chr 5:91,051,758...91,053,797
Ensembl chr 5:91,051,730...91,053,797 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21192278 NCBI chr 5:90,933,960...90,935,952
Ensembl chr 5:90,933,962...90,937,459 		JBrowse link
G Epo erythropoietin treatment ISO RGD PMID:20539178 RGD:10401059 NCBI chr 5:137,481,282...137,484,078
Ensembl chr 5:137,481,282...137,531,504 		JBrowse link
G Esr1 estrogen receptor 1 (alpha) severity ISO RGD PMID:20195535 RGD:4892252 NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614 		JBrowse link
G Esr2 estrogen receptor 2 (beta) ISO RGD PMID:16859701 RGD:8694176 NCBI chr12:76,167,193...76,224,033
Ensembl chr12:76,167,193...76,224,033 		JBrowse link
G F2 coagulation factor II ISO protein:decreased activity:blood (rat) RGD PMID:21550061 RGD:5132267 NCBI chr 2:91,442,742...91,466,799
Ensembl chr 2:91,455,665...91,466,759 		JBrowse link
G F8 coagulation factor VIII ISO protein:decreased expression:plasma RGD PMID:15748447 RGD:10450768 NCBI chr  X:74,213,950...74,426,342
Ensembl chr  X:74,216,321...74,426,221 		JBrowse link
G Gfer growth factor, augmenter of liver regeneration IEP RGD PMID:23073658 RGD:9685733 NCBI chr17:24,912,164...24,915,065
Ensembl chr17:24,912,161...24,915,130 		JBrowse link
G Gja1 gap junction protein, alpha 1 ISO RGD PMID:19077877 RGD:7207423 NCBI chr10:56,253,297...56,266,519
Ensembl chr10:56,253,426...56,278,609 		JBrowse link
G Gja5 gap junction protein, alpha 5 ISO RGD PMID:19077877 RGD:7207423 NCBI chr 3:96,939,718...96,960,950
Ensembl chr 3:96,812,009...96,984,732 		JBrowse link
G Glul glutamate-ammonia ligase treatment ISO RGD PMID:12766648 RGD:401794596 NCBI chr 1:153,775,692...153,785,469
Ensembl chr 1:153,775,690...153,785,469 		JBrowse link
G Gpt glutamic pyruvic transaminase, soluble treatment ISO RGD PMID:16141011 RGD:401717565 NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886 		JBrowse link
G Hmox1 heme oxygenase 1 severity ISO RGD PMID:20514418 PMID:20819606 RGD:10755719, RGD:10755727 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217 		JBrowse link
G Hp haptoglobin ISO RGD PMID:20016403 RGD:5147418 NCBI chr 8:110,301,760...110,305,804
Ensembl chr 8:110,301,760...110,305,804 		JBrowse link
G Hspa1a heat shock protein 1A ISO mRNA:increased expression:liver RGD PMID:22266570 RGD:7257601 NCBI chr17:35,188,335...35,191,132
Ensembl chr17:35,188,166...35,191,132 		JBrowse link
G Icam1 intercellular adhesion molecule 1 IEP
ISO		 mRNA, protein:increased expression:lung (mouse)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:21192278 PMID:19828841 RGD:4145497 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113 		JBrowse link
G Ifng interferon gamma ISO protein:increased expression:plasma RGD PMID:19439114 RGD:2311495 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797 		JBrowse link
G Il10 interleukin 10 ISO protein:increased expression:serum, lymph RGD PMID:19160132 RGD:2311060 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711 		JBrowse link
G Il18 interleukin 18 IEP protein:increased expression:plasma RGD PMID:23589298 RGD:14695541 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140 		JBrowse link
G Il1a interleukin 1 alpha ISO mRNA:increased expression:lung RGD PMID:15580020 RGD:2311100 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892 		JBrowse link
G Il1b interleukin 1 beta severity ISO mRNA:increased expression:lung
protein:increased expression:kidney, serum (rat)		 RGD PMID:17545943 PMID:21336199 PMID:15580020 RGD:1626655, RGD:7175325, RGD:2311100 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059 		JBrowse link
G Il4 interleukin 4 treatment ISO RGD PMID:24986445 RGD:10402801 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496 		JBrowse link
G Il6 interleukin 6 ISO protein:increased expression:plasma
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:21192278 PMID:21168948 RGD:5128673 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Mapk1 mitogen-activated protein kinase 1 ISO protein: increased expression: lung and liver RGD PMID:22392145 RGD:7244173 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317 		JBrowse link
G Mmp9 matrix metallopeptidase 9 treatment ISO RGD PMID:16141011 RGD:401717565 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770 		JBrowse link
G Mpo myeloperoxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21192278 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239 		JBrowse link
G Mtor mechanistic target of rapamycin kinase treatment ISO RGD PMID:24204984 RGD:10041042 NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140 		JBrowse link
G Myc myelocytomatosis oncogene treatment ISO RGD PMID:22113495 RGD:7240568 NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223 		JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha treatment ISO RGD PMID:11557243 RGD:127285020 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432 		JBrowse link
G Nos2 nitric oxide synthase 2, inducible ISO mRNA, protein:increased expression:multiple RGD PMID:15854664 RGD:1580937 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080 		JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell treatment ISO mRNA:increased expression: :multiple RGD PMID:15854664 PMID:29122552 RGD:1580937, RGD:13450929 NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472 		JBrowse link
G Otc ornithine transcarbamylase ISO protein:increased activity:serum (rat) RGD PMID:17224795 RGD:1643525 NCBI chr  X:10,118,584...10,187,275
Ensembl chr  X:10,118,544...10,187,263 		JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) ISO protein:increased phosphorylation:nucleus, liver
protein:increased phosphorylation, altered location:nucleus, endothelial cell, lung		 RGD PMID:17950078 PMID:18469645 PMID:17950083 RGD:2298842, RGD:2298781, RGD:2298841 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158 		JBrowse link
G Sirt1 sirtuin 1 treatment ISO protein:decreased expression:heart left ventricle RGD PMID:22113495 PMID:21554952 RGD:7240568, RGD:9585770 NCBI chr10:63,154,784...63,174,814
Ensembl chr10:63,154,784...63,217,483 		JBrowse link
G Slc9a1 solute carrier family 9 (sodium/hydrogen exchanger), member 1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:17724433 PMID:19384202 RGD:6771334 NCBI chr 4:133,097,022...133,151,013
Ensembl chr 4:133,097,017...133,151,013 		JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial treatment ISO RGD PMID:26073907 RGD:26923954 NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950 		JBrowse link
G Tfam transcription factor A, mitochondrial ISO RGD PMID:22469910 RGD:6767567 NCBI chr10:71,061,298...71,074,157
Ensembl chr10:71,061,294...71,074,110 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 treatment ISO RGD PMID:16141011 RGD:401717565 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502 		JBrowse link
G Timp1 tissue inhibitor of metalloproteinase 1 treatment ISO RGD PMID:16141011 RGD:401717565 NCBI chr  X:20,736,524...20,740,972
Ensembl chr  X:20,736,405...20,740,974 		JBrowse link
G Tlr4 toll-like receptor 4 severity IMP RGD PMID:25049041 RGD:14697700 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521 		JBrowse link
G Tnf tumor necrosis factor treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:21192278 PMID:24315526 RGD:10450602 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
G Trem1 triggering receptor expressed on myeloid cells 1 ameliorates ISO RGD PMID:19333144 RGD:127284838 NCBI chr17:48,539,763...48,553,955
Ensembl chr17:48,539,796...48,553,952 		JBrowse link
G Vwf Von Willebrand factor ISO protein:decreased expression:plasma RGD PMID:15748447 RGD:10450768 NCBI chr 6:125,529,911...125,663,642
Ensembl chr 6:125,523,737...125,663,642 		JBrowse link
Henoch-Schoenlein purpura term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme disease_progression ISO DNA:deletion:intron:IVS16+1464-1751del (human) RGD PMID:15315169 RGD:11038920 NCBI chr11:105,858,774...105,880,790
Ensembl chr11:105,858,771...105,880,790 		JBrowse link
G Agt angiotensinogen severity ISO DNA:missense mutation:cds:p.M235T (human)
DNA:missense mutation:cds:p.T174M (human)		 RGD PMID:16521052 PMID:20702504 RGD:11039045, RGD:11039055 NCBI chr 8:125,283,326...125,296,445
Ensembl chr 8:125,283,273...125,296,445 		JBrowse link
G C3 complement component 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:1353212 NCBI chr17:57,510,967...57,535,136
Ensembl chr17:57,510,970...57,535,136 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 susceptibility ISO DNA:snp:promoter:g.-2518C>T (human)
protein:increased expression:serum (human)		 RGD PMID:26234573 PMID:25839768 RGD:11522500, RGD:11528567 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279 		JBrowse link
G Cd86 CD86 antigen treatment ISO protein:increased expression:venous blood, B cell (human) RGD PMID:27030970 RGD:11354986 NCBI chr16:36,389,318...36,486,439
Ensembl chr16:36,424,231...36,486,443 		JBrowse link
G H2-Aa histocompatibility 2, class II antigen A, alpha susceptibility ISO DNA:polymorphisms:cds:HLA-DQA1*0301, HLA-DQA1*0302 (human) RGD PMID:11836690 RGD:5147830 NCBI chr17:34,501,718...34,506,797
Ensembl chr17:34,501,718...34,506,797 		JBrowse link
G Hmox1 heme oxygenase 1 ISO protein:increased expression:serum RGD PMID:20013271 RGD:10755701 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217 		JBrowse link
G Igf1 insulin-like growth factor 1 ISO protein:increased expression:serum RGD PMID:20013271 RGD:10755701 NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904 		JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO DNA:repeats:intron:IVS2+914_1000dup IL1RN*2 (human) RGD PMID:9186886 RGD:6909151 NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506 		JBrowse link
G Il27 interleukin 27 ISO mRNA,protein:decreased expression:peripheral blood mononuclear cell, blood serum (human)" RGD PMID:33280050 RGD:126790550 NCBI chr 7:126,188,181...126,194,197
Ensembl chr 7:126,188,182...126,194,113 		JBrowse link
G Il5 interleukin 5 ISO protein:increased expression:serum RGD PMID:16787590 RGD:11354946 NCBI chr11:53,611,621...53,615,930
Ensembl chr11:53,611,621...53,615,933 		JBrowse link
G Kng1 kininogen 1 ISO protein:increased expression:serum RGD PMID:26098644 RGD:11059888 NCBI chr16:22,876,970...22,900,828
Ensembl chr16:22,876,615...22,900,828 		JBrowse link
G Kng2 kininogen 2 ISO protein:increased expression:serum RGD PMID:26098644 RGD:11059888 NCBI chr16:22,804,602...22,847,851
Ensembl chr16:22,804,604...22,848,232 		JBrowse link
G Mefv Mediterranean fever susceptibility ISO DNA:mutations:exons:
DNA:mutations:cds:
DNA:mutation:exon:p. E148Q (human)		 RGD PMID:22451026 PMID:25232290 PMID:20602240 RGD:7349346, RGD:11531116, RGD:7349347 NCBI chr16:3,524,838...3,536,073
Ensembl chr16:3,525,082...3,535,961 		JBrowse link
G Plat plasminogen activator, tissue ISO protein:increased expression:plasma (human) RGD PMID:9543574 RGD:11541055 NCBI chr 8:23,247,655...23,272,864
Ensembl chr 8:23,247,743...23,272,860 		JBrowse link
G Plau plasminogen activator, urokinase ISO CTD Direct Evidence: therapeutic CTD PMID:9002298 PMID:12671112 NCBI chr14:20,886,730...20,893,456
Ensembl chr14:20,886,728...20,893,453 		JBrowse link
G Pon1 paraoxonase 1 susceptibility ISO DNA:missense mutations:cds:p.L55M, p.Q192R (human) RGD PMID:19967651 RGD:11552576 NCBI chr 6:5,168,101...5,193,824
Ensembl chr 6:5,168,090...5,193,946 		JBrowse link
Heparin-induced Thrombocytopenia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcgr4 Fc receptor, IgG, low affinity IV susceptibility ISO DNA:SNP:cds:p.V158F(human) RGD PMID:15191947 RGD:11040991 NCBI chr 1:170,846,495...170,857,330
Ensembl chr 1:170,846,489...170,857,330 		JBrowse link
G Il10 interleukin 10 no_association ISO DNA:repeats, haplotype:promoter
DNA:SNPs:promoter:rs1800896 (-1082G/A), rs1800871 (-819C/T), rs1800872 (-592C/A) (human)		 RGD PMID:22239992 PMID:22239992 RGD:11049164, RGD:11049164 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711 		JBrowse link
Intracranial Hemorrhages term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col4a1 collagen, type IV, alpha 1 ISO ClinVar Annotator: match by term: Intracranial Hemorrhages ClinVar PMID:7695699 PMID:8218237 PMID:9016532 PMID:16598045 PMID:17078022 More... NCBI chr 8:11,248,423...11,362,889
Ensembl chr 8:11,248,423...11,362,826 		JBrowse link
G F7 coagulation factor VII ISO CTD Direct Evidence: therapeutic CTD PMID:15595332 PMID:16159073 PMID:18617125 PMID:20172985 PMID:20522813 NCBI chr 8:13,075,499...13,085,809
Ensembl chr 8:13,076,034...13,085,809 		JBrowse link
G Hbb-b1 hemoglobin, beta adult major chain ISO mRNA:increased expression:basal ganglion, neuron, glial cell RGD PMID:21725744 RGD:10449050
G Hspb1 heat shock protein 1 ISO protein:increased expression:brain: RGD PMID:15472083 RGD:10402769 NCBI chr 5:135,916,773...135,918,417
Ensembl chr 5:135,916,773...135,918,417 		JBrowse link
G Il6 interleukin 6 susceptibility ISO DNA:polymorphism:promoter -174G>C(human) RGD PMID:15331795 RGD:12792203 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell treatment ISO RGD PMID:29203281 RGD:13504724 NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472 		JBrowse link
G Nsd2 nuclear receptor binding SET domain protein 2 ISO ClinVar Annotator: match by term: Intracranial Hemorrhages ClinVar PMID:25741868 NCBI chr 5:33,974,286...34,055,310
Ensembl chr 5:33,978,069...34,055,319 		JBrowse link
G Plat plasminogen activator, tissue ISO CTD Direct Evidence: marker/mechanism CTD PMID:2104561 PMID:3168586 PMID:7902905 PMID:8961984 PMID:11320361 More... NCBI chr 8:23,247,655...23,272,864
Ensembl chr 8:23,247,743...23,272,860 		JBrowse link
G Plau plasminogen activator, urokinase ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:10392865 PMID:10472989 PMID:10512912 PMID:17308290 PMID:21779364 RGD:6484131 NCBI chr14:20,886,730...20,893,456
Ensembl chr14:20,886,728...20,893,453 		JBrowse link
G Ppp1r1b protein phosphatase 1, regulatory inhibitor subunit 1B ISO RGD PMID:23543809 RGD:13515075 NCBI chr11:98,239,232...98,248,622
Ensembl chr11:98,239,230...98,248,622 		JBrowse link
G Psen1 presenilin 1 IMP RGD PMID:9160754 RGD:1302520 NCBI chr12:83,734,926...83,781,869
Ensembl chr12:83,734,926...83,781,973 		JBrowse link
G Serping1 serine (or cysteine) peptidase inhibitor, clade G, member 1 treatment ISO associated with Stroke RGD PMID:21779364 RGD:6484131 NCBI chr 2:84,595,704...84,605,748
Ensembl chr 2:84,595,731...84,605,788 		JBrowse link
G Shoc2 Shoc2, leucine rich repeat scaffold protein ISO mRNA:decreased expression:brain: RGD PMID:34368865 RGD:155804268 NCBI chr19:53,932,018...54,021,711
Ensembl chr19:53,932,737...54,021,564 		JBrowse link
G Slc23a1 solute carrier family 23 (nucleobase transporters), member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11984597 NCBI chr18:35,747,657...35,762,900
Ensembl chr18:35,747,657...35,760,297 		JBrowse link
G Tnf tumor necrosis factor ISO RGD PMID:16322490 RGD:1580310 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
G Trf transferrin ISO associated with Iron-Deficiency Anemia;protein:increased expression:basal ganglia RGD PMID:16671451 RGD:1601537 NCBI chr 9:103,086,075...103,107,485
Ensembl chr 9:103,081,200...103,107,643 		JBrowse link
G Ubiad1 UbiA prenyltransferase domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23533172 NCBI chr 4:148,518,952...148,529,217
Ensembl chr 4:148,518,952...148,529,228 		JBrowse link
Intracranial Subdural Hematoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gp6 glycoprotein 6 platelet exacerbates IMP RGD PMID:21258336 RGD:401824683 NCBI chr 7:4,365,852...4,400,849
Ensembl chr 7:4,366,964...4,400,743 		JBrowse link
G Mdm2 transformed mouse 3T3 cell double minute 2 treatment ISO RGD PMID:34334113 RGD:155882538 NCBI chr10:117,524,780...117,546,663
Ensembl chr10:117,524,780...117,546,663 		JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 treatment ISO protein:increased expression:brain (rat) RGD PMID:34334113 PMID:34334113 RGD:155882538, RGD:155882538 NCBI chr 2:44,873,523...45,007,378
Ensembl chr 2:44,873,644...45,007,407 		JBrowse link
Intraventricular Hemorrhage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bace1 beta-site APP cleaving enzyme 1 ISO protein:increased expression:hippocampus RGD PMID:30028260 RGD:13782136 NCBI chr 9:45,749,878...45,775,694
Ensembl chr 9:45,749,878...45,775,697 		JBrowse link
G Col4a1 collagen, type IV, alpha 1 ISO ClinVar Annotator: match by term: Intraventricular hemorrhage ClinVar PMID:7695699 PMID:8218237 PMID:9016532 PMID:16598045 PMID:17078022 More... NCBI chr 8:11,248,423...11,362,889
Ensembl chr 8:11,248,423...11,362,826 		JBrowse link
G Col4a2 collagen, type IV, alpha 2 ISO ClinVar Annotator: match by term: Intraventricular hemorrhage ClinVar PMID:25741868 PMID:33527515 NCBI chr 8:11,362,878...11,499,287
Ensembl chr 8:11,362,805...11,499,287 		JBrowse link
G Il6 interleukin 6 ISO associated with Premature Birth;protein:increased expression:serum: RGD PMID:22906886 RGD:12792208 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
Peptic Ulcer Hemorrhage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen ISO CTD Direct Evidence: marker/mechanism CTD PMID:20824505 NCBI chr 8:125,283,326...125,296,445
Ensembl chr 8:125,283,273...125,296,445 		JBrowse link
G Cyp2c65 cytochrome P450, family 2, subfamily c, polypeptide 65 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17681167 NCBI chr19:39,049,450...39,082,392
Ensembl chr19:39,049,459...39,082,388 		JBrowse link
pituitary apoplexy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crh corticotropin releasing hormone ISO CTD Direct Evidence: marker/mechanism CTD PMID:12699433 PMID:12699434 NCBI chr 3:19,747,565...19,749,560
Ensembl chr 3:19,747,565...19,749,560 		JBrowse link
platelet-type bleeding disorder 11 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gp6 glycoprotein 6 platelet ISO DNA:insertion:exon 6:c.711_712insA (human)
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Platelet-type bleeding disorder 11		 OMIM
CTD
ClinVar
RGD		 PMID:19549989 PMID:19552682 PMID:23815599 PMID:25741868 PMID:28492532 More... RGD:401794132 NCBI chr 7:4,365,852...4,400,849
Ensembl chr 7:4,366,964...4,400,743 		JBrowse link
Platelet-Type Bleeding Disorder 13 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg5 ATP binding cassette subfamily G member 5 ISO ClinVar Annotator: match by term: Impaired thromboxane A2 agonist-induced platelet aggregation ClinVar PMID:32581362 NCBI chr17:84,965,602...84,990,439
Ensembl chr17:84,965,662...84,990,439 		JBrowse link
G Tbxa2r thromboxane A2 receptor susceptibility IMP
ISO		 ClinVar Annotator: match by term: BLEEDING DISORDER, SUSCEPTIBILITY TO, DUE TO DEFECTIVE PLATELET THROMBOXANE A2 RECEPTOR | ClinVar Annotator: match by term: Bleeding disorder, platelet-type, 13, susceptibility to | ClinVar Annotator: match by term: Impaired thromboxane A2 agonist-induced platelet aggregation
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
OMIM
RGD		 PMID:2955539 PMID:7929844 PMID:8428006 PMID:8613548 PMID:19828703 More... RGD:11059528 NCBI chr10:81,164,102...81,171,008
Ensembl chr10:81,164,565...81,171,006 		JBrowse link
platelet-type bleeding disorder 15 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn1 actinin, alpha 1 ISO ClinVar Annotator: match by term: ACTN1-related condition | ClinVar Annotator: match by term: Platelet-type bleeding disorder 15
CTD Direct Evidence: marker/mechanism		 OMIM
ClinVar
CTD		 PMID:9536098 PMID:17576681 PMID:23434115 PMID:24069336 PMID:25361813 More... NCBI chr12:80,214,316...80,307,165
Ensembl chr12:80,214,321...80,307,145 		JBrowse link
G Fli1 Friend leukemia integration 1 ISO ClinVar Annotator: match by term: Bleeding disorder platelet type macrothrombocytopenia ClinVar PMID:23809206 PMID:26316623 NCBI chr 9:32,333,500...32,454,292
Ensembl chr 9:32,333,500...32,454,157 		JBrowse link
platelet-type bleeding disorder 18 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rasgrp2 RAS, guanyl releasing protein 2 ISO ClinVar Annotator: match by term: Platelet-type bleeding disorder 18 | ClinVar Annotator: match by term: RASGRP2-related condition
CTD Direct Evidence: marker/mechanism		 OMIM
ClinVar
CTD		 PMID:24958846 PMID:25741868 PMID:27235135 PMID:27663674 PMID:28492532 More... NCBI chr19:6,449,038...6,465,243
Ensembl chr19:6,449,370...6,465,246 		JBrowse link
platelet-type bleeding disorder 20 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slfn14 schlafen 14 ISO ClinVar Annotator: match by term: Platelet-type bleeding disorder 20 | ClinVar Annotator: match by term: SLFN14-related condition
CTD Direct Evidence: marker/mechanism		 OMIM
ClinVar
CTD		 PMID:25741868 PMID:26280575 PMID:26769223 PMID:28492532 PMID:29678925 More... NCBI chr11:83,165,936...83,177,552
Ensembl chr11:83,165,936...83,177,552 		JBrowse link
Platelet-Type Bleeding Disorder 21 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fli1 Friend leukemia integration 1 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Bleeding disorder, platelet-type, 21		 OMIM
CTD
ClinVar		 PMID:23809206 PMID:24100448 PMID:25741868 PMID:26316623 PMID:28255014 More... NCBI chr 9:32,333,500...32,454,292
Ensembl chr 9:32,333,500...32,454,157 		JBrowse link
platelet-type bleeding disorder 8 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Med12l mediator complex subunit 12-like ISO ClinVar Annotator: match by term: Impaired ADP-induced platelet aggregation | ClinVar Annotator: match by term: Platelet-type bleeding disorder 8 ClinVar PMID:7706468 PMID:11196645 PMID:12578987 PMID:20966167 PMID:25741868 More... NCBI chr 3:58,912,820...59,225,867
Ensembl chr 3:58,913,246...59,226,103 		JBrowse link
G P2ry12 purinergic receptor P2Y, G-protein coupled 12 ISO
IAGP		 CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Impaired ADP-induced platelet aggregation | ClinVar Annotator: match by term: Platelet-type bleeding disorder 8
OMIM:609821		 OMIM
CTD
ClinVar
MouseDO		 PMID:7706468 PMID:11196645 PMID:12578987 PMID:20966167 PMID:25741868 More... NCBI chr 3:59,123,692...59,170,408
Ensembl chr 3:59,123,693...59,170,292 		JBrowse link
platelet-type bleeding disorder 9 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itga2 integrin alpha 2 ISO ClinVar Annotator: match by term: COLLAGEN PLATELET RECEPTOR DEFICIENCY | ClinVar Annotator: match by term: Platelet-type bleeding disorder 9 ClinVar PMID:19500323 PMID:22862885 PMID:23368983 PMID:25741868 PMID:28492532 NCBI chr13:114,969,617...115,068,588
Ensembl chr13:114,969,617...115,068,636 		JBrowse link
G Mocs2 molybdenum cofactor synthesis 2 ISO ClinVar Annotator: match by term: COLLAGEN PLATELET RECEPTOR DEFICIENCY | ClinVar Annotator: match by term: Platelet-type bleeding disorder 9 ClinVar NCBI chr13:114,954,707...114,965,960
Ensembl chr13:114,954,772...114,968,811 		JBrowse link
Posttransfusion Purpura term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itgb3 integrin beta 3 ISO ClinVar Annotator: match by term: PEN(a)/PEN(b) ALLOANTIGEN POLYMORPHISM ClinVar
OMIM		 PMID:1430225 PMID:9787162 PMID:14516468 PMID:21658138 PMID:25741868 More... NCBI chr11:104,498,826...104,561,302
Ensembl chr11:104,498,826...104,561,302 		JBrowse link
Preterm Intraventricular Hemorrhage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cnot1 CCR4-NOT transcription complex, subunit 1 ISO ClinVar Annotator: match by term: Preterm intraventricular hemorrhage ClinVar PMID:25741868 NCBI chr 8:96,445,559...96,534,741
Ensembl chr 8:96,446,079...96,534,092 		JBrowse link
G Gsn gelsolin IEP protein:decreased expression:blood plasma (human) RGD PMID:28755273 RGD:329337382 NCBI chr 2:35,146,371...35,197,914
Ensembl chr 2:35,146,392...35,197,904 		JBrowse link
G Sema6b sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B ISO ClinVar Annotator: match by term: Grade I preterm intraventricular hemorrhage ClinVar PMID:31474318 NCBI chr17:56,430,085...56,447,343
Ensembl chr17:56,430,085...56,447,343 		JBrowse link
Pulmonary Hemorrhage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Elane elastase, neutrophil expressed ISO associated with Pancreatitis, Experimental, sepsis; RGD PMID:7587785 RGD:10450559 NCBI chr10:79,722,146...79,724,050
Ensembl chr10:79,722,081...79,724,049 		JBrowse link
G Psen2 presenilin 2 IMP RGD PMID:10518543 RGD:1302521 NCBI chr 1:180,054,569...180,091,030
Ensembl chr 1:180,054,569...180,091,003 		JBrowse link
purpura term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il13 interleukin 13 susceptibility ISO associated withe Sjogren's Syndrome;DNA:SNP:cds:2044 G>A(human) RGD PMID:16166103 RGD:11528572 NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529 		JBrowse link
purpura fulminans term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Proc protein C ISO CTD Direct Evidence: marker/mechanism CTD PMID:18376272 NCBI chr18:32,256,179...32,272,623
Ensembl chr18:32,256,179...32,272,623 		JBrowse link
retinal arterial tortuosity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col4a1 collagen, type IV, alpha 1 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Retinal arterial tortuosity | ClinVar Annotator: match by term: Retinal arteries, tortuosity of		 CTD
ClinVar
OMIM		 PMID:3691802 PMID:7695699 PMID:8218237 PMID:9016532 PMID:9536098 More... NCBI chr 8:11,248,423...11,362,889
Ensembl chr 8:11,248,423...11,362,826 		JBrowse link
G Kat6b K(lysine) acetyltransferase 6B ISO ClinVar Annotator: match by term: Retinal arterial tortuosity ClinVar PMID:25741868 NCBI chr14:21,549,284...21,722,546
Ensembl chr14:21,531,502...21,722,546 		JBrowse link
Spinal Epidural Hematoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plat plasminogen activator, tissue ISO CTD Direct Evidence: marker/mechanism CTD PMID:10914357 PMID:12227717 NCBI chr 8:23,247,655...23,272,864
Ensembl chr 8:23,247,743...23,272,860 		JBrowse link
Subarachnoid Hemorrhage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP-binding cassette, sub-family C member 8 treatment ISO RGD PMID:24114458 RGD:10003028 NCBI chr 7:45,753,952...45,829,441
Ensembl chr 7:45,753,947...45,829,457 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO protein:increased expression:cerebrospinal fluid RGD PMID:22230897 RGD:8695949 NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778 		JBrowse link
G Adora1 adenosine A1 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:18950269 NCBI chr 1:134,126,953...134,163,195
Ensembl chr 1:134,126,963...134,163,169 		JBrowse link
G Ager advanced glycosylation end product-specific receptor ISO mRNA, protein:increased expression:brain RGD PMID:24291745 RGD:8696000 NCBI chr17:34,816,545...34,819,911
Ensembl chr17:34,816,836...34,819,910 		JBrowse link
G Aif1 allograft inflammatory factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27157545 NCBI chr17:35,389,967...35,394,977
Ensembl chr17:35,389,967...35,395,044 		JBrowse link
G Apoe apolipoprotein E ISO GAD PMID:15118671 RGD:1331525 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113 		JBrowse link
G Aqp4 aquaporin 4 exacerbates ISO mRNA:increased expression:brain: RGD PMID:33574749 PMID:33574749 RGD:127284879, RGD:127284879 NCBI chr18:15,522,451...15,544,039
Ensembl chr18:15,522,553...15,544,039 		JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 treatment ISO RGD PMID:26163325 RGD:13782347 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004 		JBrowse link
G Becn1 beclin 1, autophagy related ISO protein:increased expression:brain RGD PMID:22521819 RGD:6483046 NCBI chr11:101,179,084...101,193,112
Ensembl chr11:101,176,778...101,193,112 		JBrowse link
G Bnip3 BCL2/adenovirus E1B interacting protein 3 treatment ISO RGD PMID:23850688 RGD:11561986 NCBI chr 7:138,492,565...138,511,235
Ensembl chr 7:138,492,565...138,511,248 		JBrowse link
G C3 complement component 3 treatment ISO RGD PMID:26518242 RGD:11040780 NCBI chr17:57,510,967...57,535,136
Ensembl chr17:57,510,970...57,535,136 		JBrowse link
G Casp3 caspase 3 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:24602480 PMID:26163325 RGD:13782347 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724 		JBrowse link
G Casp9 caspase 9 treatment ISO RGD PMID:26163325 RGD:13782347 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 ISO mRNA:increased expression:cerebral artery RGD PMID:17977275 RGD:7488893 NCBI chr 1:83,094,487...83,096,888
Ensembl chr 1:83,094,487...83,096,888 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 ISO mRNA:increased expression:lung RGD PMID:20731855 RGD:4145368 NCBI chr 5:91,039,104...91,040,980
Ensembl chr 5:91,039,100...91,040,974 		JBrowse link
G Cybb cytochrome b-245, beta polypeptide ISO Protein:increased expression:cerebral cortex
mRNA:increased expression:cerebral vessel:		 RGD PMID:16671452 PMID:12142572 RGD:1599680, RGD:11040582 NCBI chr  X:9,301,493...9,354,005
Ensembl chr  X:9,301,491...9,354,010 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 treatment ISO RGD PMID:30226536 RGD:35316073 NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157
Ensembl chr10:127,126,643...127,132,157 		JBrowse link
G Edn1 endothelin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8587695 NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466 		JBrowse link
G Ednrb endothelin receptor type B ISO CTD Direct Evidence: marker/mechanism CTD PMID:8587695 NCBI chr14:104,052,055...104,081,764
Ensembl chr14:104,052,061...104,081,838 		JBrowse link
G Epo erythropoietin treatment ISO RGD PMID:23907045 RGD:10400909 NCBI chr 5:137,481,282...137,484,078
Ensembl chr 5:137,481,282...137,531,504 		JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 treatment ISO RGD PMID:28756200 RGD:151893490 NCBI chr 1:68,071,063...69,147,756
Ensembl chr 1:68,071,345...69,147,218 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signalling 1 treatment ISO RGD PMID:29169414 PMID:30226536 RGD:34901873, RGD:35316073 NCBI chr11:106,285,474...106,378,701
Ensembl chr11:106,285,476...106,378,678 		JBrowse link
G Esr1 estrogen receptor 1 (alpha) ISO protein:increased expression:dentate gyrus RGD PMID:23465388 RGD:8553242 NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614 		JBrowse link
G Gli1 GLI-Kruppel family member GLI1 ISO mRNA, protein:increased expression:brain RGD PMID:23933201 RGD:12859044 NCBI chr10:127,165,751...127,177,448
Ensembl chr10:127,165,751...127,177,843 		JBrowse link
G Gpx3 glutathione peroxidase 3 ISO protein:increased expression:plasma RGD PMID:32326289 RGD:401827845 NCBI chr11:54,793,680...54,801,213
Ensembl chr11:54,793,279...54,801,203 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta treatment ISO RGD PMID:27026509 RGD:13792767 NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446 		JBrowse link
G Gsn gelsolin disease_progression
severity		 ISO mRNA, protein:altered expression:cerebral cortex (rat)
protein:decreased expression:blood plasma (human)		 RGD PMID:25744577 PMID:23880145 RGD:11055426, RGD:329333027 NCBI chr 2:35,146,371...35,197,914
Ensembl chr 2:35,146,392...35,197,904 		JBrowse link
G Hcn1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 ISO mRNA,protein:decreased expression:hippocampus: RGD PMID:22378889 RGD:9686397 NCBI chr13:117,738,856...118,117,564
Ensembl chr13:117,738,856...118,123,954 		JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit ISO protein:increased expression:brain RGD PMID:15703702 RGD:1626323 NCBI chr12:73,948,186...73,994,304
Ensembl chr12:73,948,149...73,994,304 		JBrowse link
G Hmox1 heme oxygenase 1 ISO mRNA:increased expression:subarachnoid space RGD PMID:16543643 PMID:14657544 PMID:19686725 RGD:1582702, RGD:1598406, RGD:4145300 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217 		JBrowse link
G Hspd1 heat shock protein 1 (chaperonin) ISO mRNA:increased expression:brain stem RGD PMID:14753490 RGD:1624246 NCBI chr 1:55,116,992...55,127,402
Ensembl chr 1:55,116,994...55,127,402 		JBrowse link
G Htr1b 5-hydroxytryptamine (serotonin) receptor 1B ISO RGD PMID:17542534 RGD:1626451 NCBI chr 9:81,510,344...81,515,885
Ensembl chr 9:81,510,344...81,515,881 		JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO mRNA:increased expression:lung (rat) RGD PMID:20731855 RGD:4145368 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113 		JBrowse link
G Il1b interleukin 1 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:27157545 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059 		JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO rat model treated with human protein RGD PMID:22679224 RGD:7051590 NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506 		JBrowse link
G Il6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27157545 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Irf9 interferon regulatory factor 9 ameliorates ISO RGD PMID:29480757 RGD:125093745 NCBI chr14:55,841,442...55,847,487
Ensembl chr14:55,841,028...55,847,487 		JBrowse link
G Kcnj10 potassium inwardly-rectifying channel, subfamily J, member 10 treatment ISO RGD PMID:22420318 RGD:8662908 NCBI chr 1:172,168,777...172,201,652
Ensembl chr 1:172,168,777...172,201,652 		JBrowse link
G Lcn2 lipocalin 2 ameliorates IMP RGD PMID:26463936 RGD:126781835 NCBI chr 2:32,274,649...32,277,751
Ensembl chr 2:32,274,645...32,278,264 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 treatment ISO RGD PMID:30226536 RGD:35316073 NCBI chr10:19,809,847...20,018,496
Ensembl chr10:19,810,218...20,018,499 		JBrowse link
G Map3k7 mitogen-activated protein kinase kinase kinase 7 treatment ISO RGD PMID:29273596 RGD:155804269 NCBI chr 4:31,963,659...32,023,470
Ensembl chr 4:31,964,097...32,023,467 		JBrowse link
G Mmp13 matrix metallopeptidase 13 ISO RGD PMID:16961140 RGD:1582545 NCBI chr 9:7,272,514...7,283,333
Ensembl chr 9:7,272,514...7,283,331 		JBrowse link
G Mmp1a matrix metallopeptidase 1a (interstitial collagenase) no_association ISO RGD PMID:11546917 RGD:1582365 NCBI chr 9:7,464,141...7,476,870
Ensembl chr 9:7,464,141...7,476,857 		JBrowse link
G Mmp1b matrix metallopeptidase 1b (interstitial collagenase) no_association ISO RGD PMID:11546917 RGD:1582365 NCBI chr 9:7,367,670...7,388,026
Ensembl chr 9:7,368,239...7,388,047 		JBrowse link
G Mmp2 matrix metallopeptidase 2 ISO RGD PMID:22475348 RGD:8657107 NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048 		JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:27157545 PMID:17410600 RGD:1642039 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770 		JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 treatment ISO RGD PMID:22304528 RGD:10412722 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985 		JBrowse link
G Ngb neuroglobin ISO protein:increased expression:cerebral cortex RGD PMID:24281943 RGD:9743950 NCBI chr12:87,144,305...87,149,313
Ensembl chr12:87,144,305...87,149,313 		JBrowse link
G Nlk nemo like kinase disease_progression ISO RGD PMID:23325309 RGD:12791279 NCBI chr11:78,457,994...78,588,848
Ensembl chr11:78,457,994...78,588,199 		JBrowse link
G Nos2 nitric oxide synthase 2, inducible IEP
ISO		 mRNA:increased expression:brainstem, basilar artery (mouse)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:17053178 PMID:21915076 RGD:5509046 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080 		JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell ISO mRNA:increased expression:parietal cortex, arteriole (rat) RGD PMID:11273938 RGD:7794687 NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472 		JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 ISO mRNA, protein:increased expression:brain RGD PMID:21259333 RGD:5133235 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838 		JBrowse link
G Nrg1 neuregulin 1 treatment ISO RGD PMID:28756200 RGD:151893490 NCBI chr 8:32,299,493...33,381,858
Ensembl chr 8:32,304,579...33,374,825
Ensembl chr 8:32,304,579...33,374,825 		JBrowse link
G Ntn1 netrin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29162556 NCBI chr11:68,100,190...68,277,652
Ensembl chr11:68,100,190...68,291,649 		JBrowse link
G Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 ISO RGD PMID:21193742 RGD:5684779 NCBI chr13:58,954,363...59,281,782
Ensembl chr13:58,954,383...59,281,784 		JBrowse link
G Pdcd10 programmed cell death 10 ISO protein:decreased expression:brain, microglial cell (rat) RGD PMID:32302649 RGD:401827168 NCBI chr 3:75,423,797...75,464,159
Ensembl chr 3:75,423,797...75,464,163 		JBrowse link
G Pdgfrb platelet derived growth factor receptor, beta polypeptide ameliorates ISO RGD PMID:29480757 RGD:125093745 NCBI chr18:61,178,194...61,218,139
Ensembl chr18:61,178,222...61,218,133 		JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta treatment ISO RGD PMID:28756200 RGD:151893490 NCBI chr 9:98,920,455...99,022,264
Ensembl chr 9:98,918,707...99,022,674 		JBrowse link
G Pkd1l1 polycystic kidney disease 1 like 1 susceptibility ISO DNA:polymorphism:cds:p.Gly243Asp(human) RGD PMID:16741147 RGD:155630602 NCBI chr11:8,782,025...8,924,365
Ensembl chr11:8,776,708...8,923,266 		JBrowse link
G Pparg peroxisome proliferator activated receptor gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:29162556 NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase treatment ISO RGD PMID:28546552 RGD:13432565 NCBI chr17:11,059,227...12,282,257
Ensembl chr17:11,059,271...12,282,248 		JBrowse link
G Ptch1 patched 1 ISO mRNA, protein:increased expression:brain RGD PMID:23933201 RGD:12859044 NCBI chr13:63,656,142...63,721,274
Ensembl chr13:63,656,142...63,721,412 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IMP RGD PMID:21725746 RGD:5508204 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978 		JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) ISO CTD Direct Evidence: marker/mechanism CTD PMID:27157545 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158 		JBrowse link
G Shh sonic hedgehog ISO mRNA, protein:increased expression:brain RGD PMID:23933201 RGD:12859044 NCBI chr 5:28,661,838...28,672,099
Ensembl chr 5:28,661,813...28,672,254 		JBrowse link
G Smo smoothened, frizzled class receptor treatment ISO RGD PMID:28149272 RGD:150521623 NCBI chr 6:29,735,480...29,761,359
Ensembl chr 6:29,735,502...29,761,364 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO mRNA, protein:increased expression, increased phosphorylation:cerebral artery RGD PMID:24517975 RGD:8694356 NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366 		JBrowse link
G Tacr1 tachykinin receptor 1 ISO RGD PMID:17542534 RGD:1626451 NCBI chr 6:82,378,990...82,537,085
Ensembl chr 6:82,379,315...82,537,085 		JBrowse link
G Tjp1 tight junction protein 1 ISO protein:altered localization RGD PMID:18854840 RGD:2325137 NCBI chr 7:64,945,913...65,177,629
Ensembl chr 7:64,945,913...65,177,529 		JBrowse link
G Tlr4 toll-like receptor 4 ISO mRNA, protein:increased expression:brain RGD PMID:19719951 RGD:4144093 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521 		JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 treatment ISO mRNA,protein:decreased expression:brain RGD PMID:30226536 PMID:30226536 RGD:35316073, RGD:35316073 NCBI chr15:99,290,828...99,307,930
Ensembl chr15:99,290,763...99,307,930 		JBrowse link
G Tnc tenascin C ISO protein:increased expression:basilar artery RGD PMID:19589197 RGD:4889600 NCBI chr 4:63,878,022...63,965,554
Ensembl chr 4:63,878,022...63,965,252 		JBrowse link
G Tnf tumor necrosis factor ISO protein:increased expression:brain
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:27157545 PMID:19719951 RGD:4144093 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
G Trem1 triggering receptor expressed on myeloid cells 1 treatment
severity		 ISO RGD PMID:30910643 PMID:33727099 RGD:127284863, RGD:127284864 NCBI chr17:48,539,763...48,553,955
Ensembl chr17:48,539,796...48,553,952 		JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 ISO protein:increased expression:entorhinal cortex RGD PMID:24114458 RGD:10003028 NCBI chr 7:44,952,579...44,983,495
Ensembl chr 7:44,952,056...44,983,204 		JBrowse link
G Unc5b unc-5 netrin receptor B ISO CTD Direct Evidence: marker/mechanism CTD PMID:29162556 NCBI chr10:60,598,373...60,667,360
Ensembl chr10:60,598,372...60,667,360 		JBrowse link
G Yap1 yes-associated protein 1 treatment ISO RGD PMID:28756200 RGD:151893490 NCBI chr 9:7,932,000...8,004,890
Ensembl chr 9:7,932,000...8,004,597 		JBrowse link
Subdural Hematoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plat plasminogen activator, tissue ISO CTD Direct Evidence: marker/mechanism CTD PMID:1899364 NCBI chr 8:23,247,655...23,272,864
Ensembl chr 8:23,247,743...23,272,860 		JBrowse link
Thrombocytopenic Purpura term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gp9 glycoprotein 9 platelet ISO RGD PMID:23103637 RGD:11040532 NCBI chr 6:87,753,115...87,756,768
Ensembl chr 6:87,755,054...87,756,750 		JBrowse link
G Itga2b integrin alpha 2b IDA RGD PMID:11493456 RGD:2316362 NCBI chr11:102,344,134...102,360,570
Ensembl chr11:102,344,123...102,360,948 		JBrowse link
G Itgb3 integrin beta 3 IMP
ISO		 associated with HIV Infections RGD PMID:11493456 PMID:8565280 RGD:2316362, RGD:10755471 NCBI chr11:104,498,826...104,561,302
Ensembl chr11:104,498,826...104,561,302 		JBrowse link
G Vwf Von Willebrand factor ISO RGD PMID:14727254 RGD:1580644 NCBI chr 6:125,529,911...125,663,642
Ensembl chr 6:125,523,737...125,663,642 		JBrowse link
thrombotic thrombocytopenic purpura term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts13 ADAM metallopeptidase with thrombospondin type 1 motif 13 ISO
IMP		 ClinVar Annotator: match by term: ADAMTS13-related condition | ClinVar Annotator: match by term: Thrombotic thrombocytopenic purpura | ClinVar Annotator: match by term: Upshaw-Schulman syndrome
CTD Direct Evidence: marker/mechanism
Adult Onset Purpura, Thrombotic Thrombocytopenic;DNA:missense mutation:cds:p.R1060W (human)
DNA:mutations:multiple (human)
protein:decreased activity:plasma (human)		 OMIM
ClinVar
CTD
RGD		 PMID:1787257 PMID:6433703 PMID:7094941 PMID:9536098 PMID:11563771 More... RGD:10449043, RGD:1598736, RGD:10449037, RGD:10449028 NCBI chr 2:26,863,363...26,899,638
Ensembl chr 2:26,863,428...26,899,640 		JBrowse link
G Cd36 CD36 molecule ISO RGD PMID:7529543 RGD:11041104 NCBI chr 5:17,986,680...18,093,828
Ensembl chr 5:17,986,688...18,093,799 		JBrowse link
G F3 coagulation factor III ISO CTD Direct Evidence: marker/mechanism CTD PMID:7740478 NCBI chr 3:121,517,186...121,528,701
Ensembl chr 3:121,517,186...121,528,697 		JBrowse link
G H2-Ab1 histocompatibility 2, class II antigen A, beta 1 ISO DNA:polymorphisms:cds:HLA-DQB1*0301 (human) RGD PMID:19922436 RGD:11041754 NCBI chr17:34,482,201...34,488,392
Ensembl chr17:34,476,663...34,488,393 		JBrowse link
G Proc protein C ISO RGD PMID:10936861 RGD:11100014 NCBI chr18:32,256,179...32,272,623
Ensembl chr18:32,256,179...32,272,623 		JBrowse link
G Tfpi tissue factor pathway inhibitor treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:7740478 PMID:7740478 RGD:11340214 NCBI chr 2:84,263,199...84,307,119
Ensembl chr 2:84,263,199...84,307,119 		JBrowse link
G Thbd thrombomodulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:7740478 NCBI chr 2:148,246,391...148,250,108
Ensembl chr 2:148,246,386...148,250,108 		JBrowse link
Thrombotic Thrombocytopenic Purpura, Acquired term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts13 ADAM metallopeptidase with thrombospondin type 1 motif 13 treatment ISO human protein in a rat model RGD PMID:9828246 PMID:26338302 RGD:10449039, RGD:10449097 NCBI chr 2:26,863,363...26,899,638
Ensembl chr 2:26,863,428...26,899,640 		JBrowse link
G Vwf Von Willebrand factor treatment ISO RGD PMID:26863353 RGD:11079195 NCBI chr 6:125,529,911...125,663,642
Ensembl chr 6:125,523,737...125,663,642 		JBrowse link
Traumatic Intracranial Hemorrhage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F7 coagulation factor VII ISO CTD Direct Evidence: therapeutic CTD PMID:20370756 NCBI chr 8:13,075,499...13,085,809
Ensembl chr 8:13,076,034...13,085,809 		JBrowse link
Traumatic Subarachnoid Hemorrhage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP-binding cassette, sub-family C member 8 treatment ISO RGD PMID:18854840 RGD:2325137 NCBI chr 7:45,753,952...45,829,441
Ensembl chr 7:45,753,947...45,829,457 		JBrowse link
Uterine Hemorrhage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F13a1 coagulation factor XIII, A1 subunit IMP RGD PMID:12933578 RGD:10450744 NCBI chr13:37,051,150...37,234,220
Ensembl chr13:37,051,152...37,234,220 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 18301
    Pathological Conditions, Signs and Symptoms 12359
      Pathologic Processes 7726
        Hemorrhage 294
          Bleeding Disorder Due To P2rx1 Defect 0
          Circumvallate Placenta Syndrome 0
          Ecchymosis 0
          Epistaxis + 3
          Exsanguination 0
          Eye Hemorrhage + 3
          Gastrointestinal Hemorrhage + 12
          Hematoma + 9
          Hematuria + 15
          Hemobilia 0
          Hemoperitoneum 0
          Hemoptysis 0
          Hemorrhagic Shock + 56
          Hemothorax + 0
          Intracranial Hemorrhages + 162
          Oral Hemorrhage + 0
          Platelet-Type Bleeding Disorder 13 2
          Platelet-Type Bleeding Disorder 21 1
          Postoperative Hemorrhage + 0
          Pulmonary Hemorrhage + 2
          Retrobulbar Hemorrhage 0
          Surgical Blood Loss 0
          Uterine Hemorrhage + 1
          hemarthrosis + 3
          hematocele of tunica vaginalis testis 0
          platelet-type bleeding disorder 11 1
          platelet-type bleeding disorder 15 2
          platelet-type bleeding disorder 18 1
          platelet-type bleeding disorder 19 0
          platelet-type bleeding disorder 20 1
          platelet-type bleeding disorder 8 2
          platelet-type bleeding disorder 9 2
          purpura + 57
paths to the root