RGD DISEASE ONTOLOGY - ANNOTATIONS
RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term: Cancer Pain
Accession: DOID:9008104
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Definition: Pain that may be caused by or related to cellular, tissue, and systemic changes that occur during NEOPLASM growth, tissue invasion, and METASTASIS.
Synonyms: exact_synonym: Cancer Associated Pain; Cancer Pains; Cancer Related Pain; Cancer-Associated Pains; Cancer-Related Pains; Neoplasm Associated Pain; Neoplasm Related Pain; Neoplasm-Associated Pains; Neoplasm-Related Pains; Oncological Pain; Oncological Pains; Oncology Pain; Oncology Pains; Tumor Associated Pain; Tumor Related Pain; Tumor-Associated Pains; Tumor-Related Pains
primary_id: MESH:D000072716
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Cxcr4
C-X-C motif chemokine receptor 4
IEP IMP
mRNA,protein:increased expression:spinal cord:
RGD
PMID:28108674 PMID:28638088
RGD:13463594 , RGD:13838657
NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
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Dlg4
discs large MAGUK scaffold protein 4
ameliorates
IMP
RGD
PMID:26738857
RGD:243048441
NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153
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Jak2
Janus kinase 2
treatment
IEP
RGD
PMID:30027795
RGD:149735350
NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
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Mir338
microRNA 338
IEP
RNA:decreased expression:spinal cord:
RGD
PMID:28108674
RGD:13463594
NCBI chr10:105,297,923...105,297,988
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Pik3cg
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
IEP
mRNA, protein:increased expression:spinal cord (rat)
RGD
PMID:25919859
RGD:152025537
NCBI chr 6:48,766,778...48,802,098
Ensembl chr 6:48,766,864...48,802,043
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Robo1
roundabout guidance receptor 1
exacerbates
IMP
RGD
PMID:26738857
RGD:243048441
NCBI chr11:10,580,863...11,621,675
Ensembl chr11:10,580,908...11,620,203
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Slit2
slit guidance ligand 2
ameliorates
IMP
RGD
PMID:26738857
RGD:243048441
NCBI chr14:62,616,337...62,955,934
Ensembl chr14:62,617,067...62,955,948
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all