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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:End Stage Liver Disease
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Accession:DOID:9007996 term browser browse the term
Definition:Final stage of a liver disease when the liver failure is irreversible and LIVER TRANSPLANTATION is needed.
Synonyms:exact_synonym: Chronic Liver Failure;   Chronic Liver Failures
 primary_id: MESH:D058625;   RDO:0007844
 xref: EFO:1001311


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End Stage Liver Disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb4 ATP-binding cassette, sub-family B member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22022477 NCBI chr 5:8,943,614...9,009,226
Ensembl chr 5:8,943,717...9,009,231 		JBrowse link
G H2-Ab1 histocompatibility 2, class II antigen A, beta 1 susceptibility ISO associated with hepatitis C;DNA:polymorphism: :HLA-DQB1*03(human) RGD PMID:11302974 RGD:36174014 NCBI chr17:34,482,201...34,488,392
Ensembl chr17:34,476,663...34,488,393 		JBrowse link
G H2-Eb1 histocompatibility 2, class II antigen E beta susceptibility ISO associated with hepatitis C;DNA:polymorphism: : HLA-DRB1*11(human) RGD PMID:11302974 RGD:36174014 NCBI chr17:34,524,841...34,535,648
Ensembl chr17:34,524,841...34,535,648 		JBrowse link
G Ifnl2 interferon lambda 2 treatment ISO DNA:SNPs:5'utr: (rs12979860, rs8099917) (human) RGD PMID:25130512 RGD:40400912 NCBI chr 7:28,208,209...28,209,957
Ensembl chr 7:28,208,261...28,209,880 		JBrowse link
G Lep leptin IEP protein:decreased expression:serum (human) RGD PMID:9640405 RGD:25330350 NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876 		JBrowse link
G Maoa monoamine oxidase A ISO CTD Direct Evidence: marker/mechanism CTD PMID:15025246 NCBI chr  X:16,485,937...16,554,051
Ensembl chr  X:16,485,937...16,554,057 		JBrowse link
G Nos1 nitric oxide synthase 1, neuronal ISO CTD Direct Evidence: marker/mechanism CTD PMID:15025246 NCBI chr 5:118,004,904...118,096,905
Ensembl chr 5:117,919,097...118,096,905 		JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a treatment ISO RGD PMID:23874752 RGD:8661754 NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447 		JBrowse link
G Tspo translocator protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:15025246 NCBI chr15:83,447,774...83,458,404
Ensembl chr15:83,447,793...83,458,404 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 18301
    disease of anatomical entity 15631
      endocrine system disease 6290
        liver disease 2939
          Hepatic Insufficiency 160
            Liver Failure 152
              End Stage Liver Disease 9
Path 2
Term Annotations click to browse term
  disease 18301
    disease of anatomical entity 15631
      gastrointestinal system disease 6748
        hepatobiliary disease 3053
          liver disease 2939
            Hepatic Insufficiency 160
              Liver Failure 152
                End Stage Liver Disease 9
paths to the root