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RGD uses the Human Disease Ontology (DO, for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

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Accession:DOID:9007993 term browser browse the term
Definition:The condition that results from excessive loss of water from a living organism.
Synonyms:exact_synonym: Water Stress
 primary_id: MESH:D003681;   RDO:0005317
For additional species annotation, visit the Alliance of Genome Resources.

show annotations for term's descendants           Sort by:
Dehydration term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AVP arginine vasopressin ISO
mRNA:increased expression:paraventricular hypothalamic nucleus, supraoptic nucleus
CTD Direct Evidence: therapeutic
PMID:2554359 PMID:17393298 RGD:2304139 NCBI chr20:3,082,556...3,084,724
Ensembl chr20:3,082,556...3,084,724
JBrowse link
G DMD dystrophin ISO protein:decreased expression:neurohypophysial lobe: RGD PMID:9858364 RGD:12880360 NCBI chr  X:31,119,222...33,339,388
Ensembl chr  X:31,097,677...33,339,609
JBrowse link
G HAP1 huntingtin associated protein 1 ISO RGD PMID:11971876 RGD:1302538 NCBI chr17:41,717,739...41,734,646
Ensembl chr17:41,717,742...41,734,644
JBrowse link
G NOS1 nitric oxide synthase 1 ISO RGD PMID:16052497 RGD:13825136 NCBI chr12:117,208,142...117,361,626
Ensembl chr12:117,208,142...117,452,170
JBrowse link
G NPY1R neuropeptide Y receptor Y1 ISO protein:increased expression:hypothalamus RGD PMID:16728491 RGD:1642311 NCBI chr 4:163,323,962...163,344,689
Ensembl chr 4:163,323,962...163,344,832
JBrowse link
G OXT oxytocin/neurophysin I prepropeptide ISO mRNA:increased expression:paraventricular hypothalamic nucleus, supraoptic nucleus RGD PMID:17393298 RGD:2304139 NCBI chr20:3,071,620...3,072,517
Ensembl chr20:3,071,620...3,072,517
JBrowse link
G P2RY2 purinergic receptor P2Y2 ISO mRNA, protein:decreased expression:inner renal medulla RGD PMID:15687250 RGD:2316687 NCBI chr11:73,218,281...73,242,427
Ensembl chr11:73,218,281...73,242,427
JBrowse link
G PCSK1 proprotein convertase subtilisin/kexin type 1 ISO associated with Protein-Energy Malnutrition; protein:increased expression:pituitary (rat) RGD PMID:12411741 RGD:2308904 NCBI chr 5:96,390,333...96,433,248
Ensembl chr 5:96,390,333...96,434,143
JBrowse link
G PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor ISO RGD PMID:17412804 RGD:1642352 NCBI chr  X:48,831,096...48,835,610
Ensembl chr  X:48,831,096...48,835,610
JBrowse link
G PDIA3 protein disulfide isomerase family A member 3 ISO protein:increased expression:brain: RGD PMID:17412804 RGD:1642352 NCBI chr15:43,746,438...43,773,278
Ensembl chr15:43,746,394...43,773,279
JBrowse link
G YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta ISO mRNA, protein:increased expression:supraoptic nucleus, pituitary RGD PMID:17927670 RGD:9587478 NCBI chr 8:100,916,523...100,953,382
Ensembl chr 8:100,916,523...100,953,388
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 22067
    Pathological Conditions, Signs and Symptoms 13137
      Pathologic Processes 9099
        Dehydration 11
Path 2
Term Annotations click to browse term
  disease 22067
    Nutritional and Metabolic Diseases 7386
      disease of metabolism 7386
        Water-Electrolyte Imbalance 63
          Dehydration 11
paths to the root