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RGD uses the Human Disease Ontology (DO, for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

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Accession:DOID:9007993 term browser browse the term
Definition:The condition that results from excessive loss of water from a living organism.
Synonyms:exact_synonym: Water Stress
 primary_id: MESH:D003681
 xref: EFO:0009385

show annotations for term's descendants           Sort by:
Dehydration term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Avp arginine vasopressin IEP
mRNA:increased expression:paraventricular hypothalamic nucleus, supraoptic nucleus
CTD Direct Evidence: therapeutic
PMID:2554359 PMID:17393298 RGD:2304139 NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425
JBrowse link
G Dmd dystrophin IEP protein:decreased expression:neurohypophysial lobe: RGD PMID:9858364 RGD:12880360 NCBI chr  X:47,272,324...49,504,219
Ensembl chr  X:47,272,331...49,504,207
JBrowse link
G Hap1 huntingtin-associated protein 1 ISO RGD PMID:11971876 RGD:1302538 NCBI chr10:85,277,890...85,286,126
Ensembl chr10:85,277,890...85,286,126
JBrowse link
G Nos1 nitric oxide synthase 1 IEP RGD PMID:16052497 RGD:13825136 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
JBrowse link
G Npy1r neuropeptide Y receptor Y1 IEP protein:increased expression:hypothalamus RGD PMID:16728491 RGD:1642311 NCBI chr16:23,037,788...23,047,330
Ensembl chr16:23,037,789...23,046,759
JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide IEP mRNA:increased expression:paraventricular hypothalamic nucleus, supraoptic nucleus RGD PMID:17393298 RGD:2304139 NCBI chr 3:117,782,650...117,783,490
Ensembl chr 3:117,782,650...117,783,490
JBrowse link
G P2ry2 purinergic receptor P2Y2 IEP mRNA, protein:decreased expression:inner renal medulla RGD PMID:15687250 RGD:2316687 NCBI chr 1:155,352,050...155,367,423
Ensembl chr 1:155,351,165...155,367,632
JBrowse link
G Pcsk1 proprotein convertase subtilisin/kexin type 1 IEP associated with Protein-Energy Malnutrition; protein:increased expression:pituitary (rat) RGD PMID:12411741 RGD:2308904 NCBI chr 2:4,395,543...4,442,434
Ensembl chr 2:4,395,543...4,442,434
JBrowse link
G Pcsk1n proprotein convertase subtilisin/kexin type 1 inhibitor IEP RGD PMID:17412804 RGD:1642352 NCBI chr  X:14,580,036...14,583,478
Ensembl chr  X:14,580,038...14,583,566
JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 IEP protein:increased expression:brain: RGD PMID:17412804 RGD:1642352 NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236
JBrowse link
G Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta IEP mRNA, protein:increased expression:supraoptic nucleus, pituitary RGD PMID:17927670 RGD:9587478 NCBI chr 7:67,941,353...67,963,651
Ensembl chr 7:67,940,017...67,963,668
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 21089
    Pathological Conditions, Signs and Symptoms 13265
      Pathologic Processes 7963
        Dehydration 11
Path 2
Term Annotations click to browse term
  disease 21089
    Nutritional and Metabolic Diseases 8105
      disease of metabolism 8105
        Water-Electrolyte Imbalance 104
          Dehydration 11
paths to the root