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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Sepsis-Associated Encephalopathy
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Accession:DOID:9007842 term browser browse the term
Definition:Acute neurological dysfunction during severe SEPSIS in the absence of direct brain infection characterized by systemic inflammation and BLOOD BRAIN BARRIER perturbation.
Synonyms:exact_synonym: Sepsis Associated Delirium;   Sepsis Associated Deliriums;   Sepsis Associated Encephalopathies
 primary_id: MESH:D065166



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Sepsis-Associated Encephalopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jak2 Janus kinase 2 treatment IDA RGD PMID:23236988 RGD:10403076 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Nefh neurofilament heavy chain severity ISO RGD PMID:30677080 RGD:27226881 NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351
JBrowse link
G Nefl neurofilament light chain disease_progression ISO RGD PMID:30677080 RGD:27226881 NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793
JBrowse link
G Stat3 signal transducer and activator of transcription 3 treatment IDA RGD PMID:23236988 RGD:10403076 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19047
    disease of anatomical entity 18381
      nervous system disease 14255
        central nervous system disease 12587
          brain disease 11812
            Sepsis-Associated Encephalopathy 4
paths to the root