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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Sepsis-Associated Encephalopathy
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Accession:DOID:9007842 term browser browse the term
Definition:Acute neurological dysfunction during severe SEPSIS in the absence of direct brain infection characterized by systemic inflammation and BLOOD BRAIN BARRIER perturbation.
Synonyms:exact_synonym: Sepsis Associated Delirium;   Sepsis Associated Deliriums;   Sepsis Associated Encephalopathies
 primary_id: MESH:D065166


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Sepsis-Associated Encephalopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G JAK2 Janus kinase 2 treatment ISO RGD PMID:23236988 RGD:10403076 NCBI chr 9:4,984,390...5,129,948
Ensembl chr 9:4,984,390...5,129,948 		JBrowse link
G NEFH neurofilament heavy chain severity IEP RGD PMID:30677080 RGD:27226881 NCBI chr22:29,480,218...29,491,390
Ensembl chr22:29,480,218...29,491,390 		JBrowse link
G NEFL neurofilament light chain disease_progression IEP RGD PMID:30677080 RGD:27226881 NCBI chr 8:24,950,955...24,956,612
Ensembl chr 8:24,950,955...24,956,721 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 treatment ISO RGD PMID:23236988 RGD:10403076 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 97386
    disease of anatomical entity 91015
      nervous system disease 53020
        central nervous system disease 38426
          brain disease 36131
            Sepsis-Associated Encephalopathy 4
paths to the root