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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Sepsis-Associated Encephalopathy
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Accession:DOID:9007842 term browser browse the term
Definition:Acute neurological dysfunction during severe SEPSIS in the absence of direct brain infection characterized by systemic inflammation and BLOOD BRAIN BARRIER perturbation.
Synonyms:exact_synonym: Sepsis Associated Delirium;   Sepsis Associated Deliriums;   Sepsis Associated Encephalopathies
 primary_id: MESH:D065166;   RDO:0015962
For additional species annotation, visit the Alliance of Genome Resources.


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Sepsis-Associated Encephalopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jak2 Janus kinase 2 treatment IDA RGD PMID:23236988 RGD:10403076 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509
JBrowse link
G Nefh neurofilament heavy severity ISO RGD PMID:30677080 RGD:27226881 NCBI chr14:85,181,572...85,191,557
Ensembl chr14:85,181,572...85,191,557
JBrowse link
G Nefl neurofilament light disease_progression ISO RGD PMID:30677080 RGD:27226881 NCBI chr15:44,799,378...44,803,251
Ensembl chr15:44,799,334...44,804,574
JBrowse link
G Stat3 signal transducer and activator of transcription 3 treatment IDA RGD PMID:23236988 RGD:10403076 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16023
    disease of anatomical entity 15278
      nervous system disease 10897
        central nervous system disease 9045
          brain disease 8370
            Sepsis-Associated Encephalopathy 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.