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RGD uses the Human Disease Ontology (DO, for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Drug Hypersensitivity Syndrome
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Accession:DOID:9007806 term browser browse the term
Definition:Severe drug eruption characterized by high fever, erythematous rash and inflammation of internal organ(s).
Synonyms:exact_synonym: DRESS Syndrome;   DRESS Syndromes;   Drug Hypersensitivity Syndromes;   Drug Reaction with Eosinophilia and Systemic Symptoms;   Drug Reaction with Eosinophilia and Systemic Symptoms Syndrome
 primary_id: MESH:D063926;   RDO:0015829
For additional species annotation, visit the Alliance of Genome Resources.

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Drug Hypersensitivity Syndrome term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hspa1l heat shock protein family A (Hsp70) member 1 like ISO DNA:polymorphism, haplotype: :p.M493T (human) RGD PMID:15024131 RGD:8662461 NCBI chr20:4,879,998...4,965,191
Ensembl chr20:4,959,294...4,964,963
JBrowse link
G Il1b interleukin 1 beta ISO DNA:SNP:promoter:-511C>T (rs 16944) (human) RGD PMID:23461376 RGD:11051970 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO DNA:SNP:intron:rs2234663 (human) RGD PMID:23461376 RGD:11051970 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16085
    syndrome 7041
      Drug Hypersensitivity Syndrome 3
Path 2
Term Annotations click to browse term
  disease 16085
    disease of anatomical entity 15340
      Immune & Inflammatory Diseases 3590
        immune system disease 2960
          allergic disease 574
            drug allergy 103
              Drug Eruptions 61
                Drug Hypersensitivity Syndrome 3
paths to the root