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RGD uses the Human Disease Ontology (DO, for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Propofol Infusion Syndrome
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Accession:DOID:9007655 term browser browse the term
Definition:Rare and often fatal drug complication which affects patients undergoing long-term treatment with high doses of PROPOFOL. It is characterized by METABOLIC ACIDOSIS; HYPERLIPIDEMIA; RHABDOMYOLYSIS; cardiovascular CIRCULATORY COLLAPSE; CARDIAC FAILURE; and KIDNEY FAILURE.
Synonyms:exact_synonym: Propofol Infusion Syndromes;   Propofol Related Infusion Syndrome;   Propofol Syndrome;   Propofol Syndromes;   Propofol-Related Infusion Syndromes
 primary_id: MESH:D000072736;   RDO:0016125

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Propofol Infusion Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
S SS/JrHsdMcwi induced IAGP RGD PMID:17589973 RGD:1626639

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 21128
    syndrome 10832
      Propofol Infusion Syndrome 1
Path 2
Term Annotations click to browse term
  disease 21128
    Chemically-Induced Disorders 1385
      Drug-Related Side Effects and Adverse Reactions 660
        Propofol Infusion Syndrome 1
paths to the root