Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Heart Injuries
go back to main search page
Accession:DOID:9007588 term browser browse the term
Definition:General or unspecified injuries to the heart.
Synonyms:exact_synonym: Heart Injury;   Traumatic Cardiac Rupture;   Traumatic Cardiac Ruptures;   Traumatic Heart Rupture;   Traumatic Heart Ruptures
 primary_id: MESH:D006335
 xref: EFO:0009506


show annotations for term's descendants           Sort by:
Heart Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh2 aldehyde dehydrogenase 2 family member ISO CTD Direct Evidence: therapeutic CTD PMID:23500772 NCBI chr12:40,610,244...40,643,220
Ensembl chr12:40,610,224...40,643,219 		JBrowse link
G Fis1 fission, mitochondrial 1 IEP mRNA, protein:increased expression:heart (rat) RGD PMID:25677476 RGD:12437078 NCBI chr12:25,345,239...25,360,135
Ensembl chr12:25,345,239...25,349,335 		JBrowse link
G Il1b interleukin 1 beta ameliorates IEP
ISO 		protein:increased expression:spinal cord
associated with obesity 		RGD PMID:17719662 PMID:32084395 RGD:7401227, RGD:242905211 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il6 interleukin 6 ameliorates ISO associated with obesity RGD PMID:32084395 RGD:242905211 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Mirlet7f2 microRNA let-7f-2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31570982 NCBI chr  X:24,460,045...24,460,127
Ensembl chr  X:24,460,045...24,460,127 		JBrowse link
G Myl1 myosin, light chain 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19854236 Ensembl chr 9:75,887,227...75,907,971 JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase IEP mRNA, protein:increased expression:heart (rat) RGD PMID:25677476 RGD:12437078 NCBI chr11:84,612,943...84,690,025
Ensembl chr11:84,615,340...84,689,955 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 ameliorates ISO associated with obesity RGD PMID:32084395 RGD:242905211 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
G Tnf tumor necrosis factor ameliorates ISO associated with obesity RGD PMID:32084395 RGD:242905211 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tnnt2 troponin T2, cardiac type ISO CTD Direct Evidence: marker/mechanism CTD PMID:19854236 NCBI chr13:49,819,123...49,837,125
Ensembl chr13:49,822,304...49,837,125 		JBrowse link
Acute Heart Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccn1 cellular communication network factor 1 ameliorates ISO RGD PMID:23329650 RGD:329845572 NCBI chr 2:237,222,730...237,225,689
Ensembl chr 2:237,222,432...237,225,883 		JBrowse link
G Mfn1 mitofusin 1 IEP mRNA, protein:increased expression:heart (rat) RGD PMID:25677476 RGD:12437078 NCBI chr 2:117,240,525...117,288,017
Ensembl chr 2:117,241,759...117,290,190 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19167
    Wounds and Injuries 1005
      Thoracic Injuries 315
        Heart Injuries 12
          Acute Heart Injury 2
          Myocardial Contusions + 0
paths to the root