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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Hantavirus Infections
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Accession:DOID:9007533 term browser browse the term
Definition:Infections with viruses of the genus HANTAVIRUS. This is associated with at least four clinical syndromes: HEMORRHAGIC FEVER WITH RENAL SYNDROME caused by viruses of the Hantaan group; a milder form of HFRS caused by SEOUL VIRUS; nephropathia epidemica caused by PUUMALA VIRUS; and HANTAVIRUS PULMONARY SYNDROME caused by SIN NOMBRE VIRUS.
Synonyms:exact_synonym: Hantavirus Infection
 primary_id: MESH:D018778;   RDO:0005767
For additional species annotation, visit the Alliance of Genome Resources.



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Hantavirus Infections term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itgb3 integrin subunit beta 3 ISO RGD PMID:15886525 RGD:6907410 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
JBrowse link
G Mki67 marker of proliferation Ki-67 ISO RGD PMID:21795350 RGD:6483519 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
Hantavirus hemorrhagic fever with renal syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin severity ISO RGD PMID:14555823 RGD:11035280 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Apoc3 apolipoprotein C3 disease_progression ISO RGD PMID:20797315 RGD:7207210 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583
JBrowse link
G Cd163 CD163 molecule exacerbates ISO protein:increased expression:blood plasma (human)
protein:increased expression:CD14-positive, CD16-positive monocyte, blood plasma (human)
protein:increased expression:CD14-positive monocyte (human)
RGD PMID:25789628 PMID:25392926 PMID:29857122 RGD:127285679, RGD:127345131, RGD:127285683 NCBI chr 4:157,085,080...157,118,470
Ensembl chr 4:157,085,093...157,117,878
JBrowse link
G Ifng interferon gamma severity ISO protein:increased expression:serum RGD PMID:22613426 RGD:6893374 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 severity ISO RGD PMID:25658420 RGD:40400702 NCBI chr 9:42,661,694...42,727,266
Ensembl chr 9:42,697,192...42,727,256
JBrowse link
G Il2ra interleukin 2 receptor subunit alpha ISO protein:increased expression:T cell RGD PMID:21436245 RGD:5147436 NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697
JBrowse link
G Il33 interleukin 33 severity ISO RGD PMID:25658420 RGD:40400702 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373
JBrowse link
G Itgb3 integrin subunit beta 3 severity ISO protein:increased expression:platelet RGD PMID:18419255 RGD:6907404 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
JBrowse link
G RT1-Db1 RT1 class II, locus Db1 susceptibility ISO DNA:polymorphism:cds:HLA-DRB1*0401-0411, HLA-DRB1*1001, HLA-DRB1*1101-1105, HLA-DRB1*1201-1202 and HLA-DRB1*1305 (human) RGD PMID:25169964 RGD:40818303 NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258
JBrowse link
Korean hemorrhagic fever term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp3 forkhead box P3 IEP mRNA:increased expression:lung RGD PMID:17878294 RGD:2325989 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838
JBrowse link
G Il2ra interleukin 2 receptor subunit alpha treatment IMP RGD PMID:17878294 RGD:2325989 NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 18109
    disease by infectious agent 2133
      viral infectious disease 1672
        RNA Virus Infections 1383
          Bunyaviridae Infections 14
            Hantavirus Infections 11
              Hantavirus hemorrhagic fever with renal syndrome + 10
              hantavirus pulmonary syndrome 0
paths to the root