RGD DISEASE ONTOLOGY - ANNOTATIONS
RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term: Chemical and Drug Induced Liver Injury
Accession: DOID:9007383
browse the term
Definition: A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.
Synonyms: exact_synonym: Chemically Induced Liver Toxicity; Drug Induced Acute Liver Injury; Drug Induced Liver Disease; Drug Induced Liver Injury; Drug-Induced Liver Diseases; Drug-Induced Liver Injuries; Toxic Hepatitis; chemically-induced liver toxicities; hepatotoxicity; toxic hepatitides
narrow_synonym: Drug-induced liver injury due to flucloxacillin
primary_id: MESH:D056486
alt_id: RDO:0007742
xref: EFO:0004228 ; EFO:0011052 ; NCI:C84427
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AASS
aminoadipate-semialdehyde synthase
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 7:122,073,549...122,144,249
Ensembl chr 7:122,064,583...122,144,308
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ABCB1
ATP binding cassette subfamily B member 1
severity susceptibility
ISO IAGP EXP
DNA:SNP::2677G>T/A(rs2032582)(human) CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:20623750 PMID:26134275 PMID:26134275 PMID:27296832
RGD:11041130 , RGD:14700895
NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
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ABCB11
ATP binding cassette subfamily B member 11
severity
IAGP
DNA:SNP: :rs2287616(human)
RGD
PMID:27293027
RGD:14402413
NCBI chr 2:168,915,390...169,031,324
Ensembl chr 2:168,915,498...169,031,324
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ABCC1
ATP binding cassette subfamily C member 1 (ABCC1 blood group)
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:18466103
NCBI chr16:15,949,143...16,143,053
Ensembl chr16:15,949,138...16,143,257
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ABCC2
ATP binding cassette subfamily C member 2
susceptibility
EXP IAGP IEP
CTD Direct Evidence: marker/mechanism DNA:polymorphism:promoter:-24C>T(human)
CTD RGD
PMID:18381794 PMID:18466103 PMID:17241877 PMID:25196354
RGD:14700814 , RGD:14700812
NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594
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ABI1
abl interactor 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr10:26,746,596...26,860,958
Ensembl chr10:26,746,593...26,861,087
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ACE
angiotensin I converting enzyme
ISO
mRNA:increased expression:liver (rat)
RGD
PMID:25143335
RGD:25671447
NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380
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ACOX3
acyl-CoA oxidase 3, pristanoyl
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 4:8,355,305...8,440,723
Ensembl chr 4:8,366,282...8,440,723
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ACSL1
acyl-CoA synthetase long chain family member 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 4:184,755,595...184,826,594
Ensembl chr 4:184,755,595...184,826,818
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ACTB
actin beta
ISO EXP
mRNA:increased expression:liver CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:25231249 PMID:22563491
RGD:9587759
NCBI chr 7:5,527,148...5,530,601
Ensembl chr 7:5,526,409...5,563,902
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ACTN4
actinin alpha 4
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr19:38,647,649...38,731,589
Ensembl chr19:38,647,649...38,731,589
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ACTR3
actin related protein 3
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 2:113,889,934...113,962,596
Ensembl chr 2:113,890,063...113,962,596
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ADA
adenosine deaminase
ISO
protein:increased expression:liver
RGD
PMID:21161045
RGD:5128859
NCBI chr20:44,619,522...44,651,699
Ensembl chr20:44,584,896...44,652,252
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ADAM8
ADAM metallopeptidase domain 8
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:24646716
NCBI chr10:133,262,423...133,276,868
Ensembl chr10:133,262,420...133,276,868
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ADIPOQ
adiponectin, C1Q and collagen domain containing
EXP
CTD Direct Evidence: therapeutic
CTD
PMID:20709802
NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463
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ADIPOR2
adiponectin receptor 2
severity
ISO
associated with obesity, LPS;mRNA:decreased expression:liver (rat)
RGD
PMID:23838384
RGD:8695926
NCBI chr12:1,691,070...1,788,674
Ensembl chr12:1,688,574...1,788,674
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ADORA2B
adenosine A2b receptor
EXP
CTD Direct Evidence: therapeutic
CTD
PMID:35292334
NCBI chr17:15,850,362...15,975,746
Ensembl chr17:15,945,130...15,975,746
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AGT
angiotensinogen
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:29499335
NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576
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AHR
aryl hydrocarbon receptor
EXP ISO
CTD Direct Evidence: marker/mechanism|therapeutic mRNA:decreased expression:liver (rat)
CTD RGD
PMID:21890736 PMID:34848246 PMID:28959666
RGD:401794432
NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152
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AIFM1
apoptosis inducing factor mitochondria associated 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25743375
NCBI chr X:130,129,362...130,165,841
Ensembl chr X:130,124,666...130,165,879
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AK4
adenylate kinase 4
ISO
protein:increased expression:liver (rat)
RGD
PMID:16538043
RGD:2301096
NCBI chr 1:65,147,552...65,232,145
Ensembl chr 1:65,147,549...65,232,145
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AKR1A1
aldo-keto reductase family 1 member A1
ISO EXP
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:32805337 PMID:29763686
RGD:27226688
NCBI chr 1:45,550,826...45,570,049
Ensembl chr 1:45,550,543...45,570,049
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ALB
albumin
treatment
EXP ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:18779383 PMID:22310181 PMID:27567545
RGD:14694844
NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482
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ALDH1L2
aldehyde dehydrogenase 1 family member L2
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr12:105,019,790...105,084,458
Ensembl chr12:105,019,784...105,107,643
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ALDH2
aldehyde dehydrogenase 2 family member
severity susceptibility
ISO
protein:increased expression:liver DNA:deletion:exon 3 (mouse)
RGD
PMID:21138988 PMID:30121625 PMID:24492981
RGD:7241599 , RGD:15036810 , RGD:14975148
NCBI chr12:111,766,933...111,817,532
Ensembl chr12:111,766,887...111,817,532
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ALDH9A1
aldehyde dehydrogenase 9 family member A1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 1:165,662,216...165,698,562
Ensembl chr 1:165,662,216...165,698,562
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ALDOB
aldolase, fructose-bisphosphate B
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:16115720
NCBI chr 9:101,420,560...101,435,774
Ensembl chr 9:101,420,560...101,449,664
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AMBP
alpha-1-microglobulin/bikunin precursor
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:18779383
NCBI chr 9:114,060,127...114,078,300
Ensembl chr 9:114,060,127...114,078,328
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ANXA2
annexin A2
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr15:60,347,151...60,397,986
Ensembl chr15:60,347,134...60,402,883
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ANXA6
annexin A6
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 5:151,100,706...151,157,779
Ensembl chr 5:151,100,706...151,157,815
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APOA1
apolipoprotein A1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:16099942
NCBI chr11:116,835,751...116,837,622
Ensembl chr11:116,835,751...116,837,622
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APOE
apolipoprotein E
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:16099942
NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393
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APOH
apolipoprotein H
ISO EXP
mRNA:increased expression:plasma: CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:16099942 PMID:23288050
RGD:10054107
NCBI chr17:66,212,033...66,229,415
Ensembl chr17:66,212,033...66,256,525
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ARG1
arginase 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:22872058
NCBI chr 6:131,573,226...131,584,329
Ensembl chr 6:131,470,832...131,584,332
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ARNT
aryl hydrocarbon receptor nuclear translocator
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:20935161
NCBI chr 1:150,809,713...150,876,599
Ensembl chr 1:150,809,713...150,876,708
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ATG5
autophagy related 5
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:22491424
NCBI chr 6:106,184,476...106,325,760
Ensembl chr 6:106,045,423...106,325,791
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ATOH8
atonal bHLH transcription factor 8
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 2:85,753,991...85,791,383
Ensembl chr 2:85,751,344...85,791,383
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ATP6V1D
ATPase H+ transporting V1 subunit D
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr14:67,337,872...67,359,804
Ensembl chr14:67,294,371...67,360,265
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BAD
BCL2 associated agonist of cell death
treatment
ISO
RGD
PMID:25447754
RGD:10053709
NCBI chr11:64,269,828...64,284,704
Ensembl chr11:64,269,830...64,284,704
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BAX
BCL2 associated X, apoptosis regulator
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:17906064
NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
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BDH1
3-hydroxybutyrate dehydrogenase 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 3:197,509,783...197,573,343
Ensembl chr 3:197,509,783...197,573,323
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BDKRB2
bradykinin receptor B2
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:30685357
NCBI chr14:96,204,839...96,244,164
Ensembl chr14:96,204,679...96,244,166
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BLVRB
biliverdin reductase B
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr19:40,447,768...40,465,745
Ensembl chr19:40,447,765...40,465,764
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BMAL1
basic helix-loop-helix ARNT like 1
EXP
CTD Direct Evidence: therapeutic
CTD
PMID:36602574
NCBI chr11:13,276,652...13,387,266
Ensembl chr11:13,276,652...13,387,266
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BPNT1
3'(2'), 5'-bisphosphate nucleotidase 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 1:220,057,482...220,089,788
Ensembl chr 1:220,057,482...220,090,462
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BRD4
bromodomain containing 4
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr19:15,235,519...15,332,539
Ensembl chr19:15,235,519...15,332,545
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BTD
biotinidase
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:15469856
NCBI chr 3:15,601,361...15,722,516
Ensembl chr 3:15,601,341...15,722,311
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C3
complement C3
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:16099942
NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562
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CA3
carbonic anhydrase 3
ISO EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513 PMID:25231249
NCBI chr 8:85,438,859...85,449,040
Ensembl chr 8:85,373,436...85,449,040
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CABP1
calcium binding protein 1
ISO
protein:increased expression:liver
RGD
PMID:21138988
RGD:7241599
NCBI chr12:120,640,626...120,680,866
Ensembl chr12:120,640,626...120,667,324
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CADPS2
calcium dependent secretion activator 2
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:26881866
NCBI chr 7:122,318,411...122,886,460
Ensembl chr 7:122,318,411...122,886,759
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CANX
calnexin
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 5:179,678,656...179,731,641
Ensembl chr 5:179,678,628...179,731,641
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CAP1
cyclase associated actin cytoskeleton regulatory protein 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 1:40,040,240...40,072,648
Ensembl chr 1:40,040,233...40,072,649
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CASP8
caspase 8
treatment
ISO
RGD
PMID:25447754
RGD:10053709
NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836
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CAST
calpastatin
ISO
RGD
PMID:16871587
RGD:5683869
NCBI chr 5:95,961,429...96,774,683
Ensembl chr 5:96,525,267...96,779,595 Ensembl chr 5:96,525,267...96,779,595
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CAT
catalase
EXP ISO
CTD Direct Evidence: marker/mechanism protein:decreased expression:liver
CTD RGD
PMID:20623750 PMID:25231249 PMID:21138988
RGD:7241599
NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
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CCDC80
coiled-coil domain containing 80
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 3:112,596,797...112,641,143
Ensembl chr 3:112,596,797...112,649,530
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CCL2
C-C motif chemokine ligand 2
treatment
EXP ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:20623750 PMID:21813474 PMID:30663942
RGD:14995466 , RGD:14995458
NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208
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CCR2
C-C motif chemokine receptor 2
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:20623750
NCBI chr 3:46,354,111...46,360,940
Ensembl chr 3:46,353,864...46,360,940
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CCR5
C-C motif chemokine receptor 5
susceptibility
ISO
acetaminophen
RGD
PMID:24770590
RGD:14401733
NCBI chr 3:46,370,142...46,376,206
Ensembl chr 3:46,370,946...46,376,206
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CCT3
chaperonin containing TCP1 subunit 3
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 1:156,308,968...156,338,292
Ensembl chr 1:156,308,968...156,367,873
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CCT5
chaperonin containing TCP1 subunit 5
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 5:10,249,921...10,266,412
Ensembl chr 5:10,249,929...10,266,389
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CDC25B
cell division cycle 25B
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr20:3,786,951...3,806,115
Ensembl chr20:3,786,772...3,806,121
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CDS1
CDP-diacylglycerol synthase 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 4:84,583,127...84,651,334
Ensembl chr 4:84,583,127...84,651,334
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CELA1
chymotrypsin like elastase 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr12:51,328,442...51,346,679
Ensembl chr12:51,328,442...51,346,679
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CFAP20
cilia and flagella associated protein 20
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr16:58,113,592...58,129,381
Ensembl chr16:58,113,592...58,129,381
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CFH
complement factor H
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 1:196,652,043...196,747,504
Ensembl chr 1:196,651,754...196,752,476
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CHRM3
cholinergic receptor muscarinic 3
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:20197374
NCBI chr 1:239,386,568...239,915,450
Ensembl chr 1:239,386,565...239,915,452
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CKB
creatine kinase B
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr14:103,519,667...103,522,830
Ensembl chr14:103,519,667...103,522,833
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CLU
clusterin
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:20623750
NCBI chr 8:27,596,917...27,614,700
Ensembl chr 8:27,596,917...27,614,700
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COL14A1
collagen type XIV alpha 1 chain
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 8:120,124,454...120,373,573
Ensembl chr 8:120,059,780...120,373,573
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COL3A1
collagen type III alpha 1 chain
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:16679477
NCBI chr 2:188,974,373...189,012,746
Ensembl chr 2:188,974,373...189,012,746
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COMT
catechol-O-methyltransferase
ISO
protein:decreased expression:liver
RGD
PMID:21138988
RGD:7241599
NCBI chr22:19,941,772...19,969,975
Ensembl chr22:19,941,371...19,969,975
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COQ9
coenzyme Q9
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr16:57,447,479...57,461,270
Ensembl chr16:57,447,425...57,461,270
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CP
ceruloplasmin
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 3:149,162,414...149,221,829
Ensembl chr 3:149,162,410...149,221,829
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CPB2
carboxypeptidase B2
ISO
mRNA,protein:increased expression,increased activity:liver,plasma
RGD
PMID:19386599
RGD:7243112
NCBI chr13:46,053,186...46,105,033
Ensembl chr13:46,053,186...46,105,033
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CPS1
carbamoyl-phosphate synthase 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 2:210,477,685...210,679,107
Ensembl chr 2:210,477,682...210,679,107
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CPT1A
carnitine palmitoyltransferase 1A
ISO
mRNA:decreased expression:liver (rat)
RGD
PMID:28959666
RGD:401794432
NCBI chr11:68,754,620...68,844,277
Ensembl chr11:68,754,620...68,844,410
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CRP
C-reactive protein
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589
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CSF3
colony stimulating factor 3
EXP
CTD Direct Evidence: therapeutic
CTD
PMID:20005281 PMID:33882750
NCBI chr17:40,015,440...40,017,813
Ensembl chr17:40,015,361...40,017,813
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CTNNB1
catenin beta 1
EXP
CTD Direct Evidence: therapeutic
CTD
PMID:19679878
NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096
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CTSE
cathepsin E
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 1:206,009,264...206,023,895
Ensembl chr 1:206,008,535...206,023,909
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CXCL1
C-X-C motif chemokine ligand 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:16118408
NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308
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CXCL10
C-X-C motif chemokine ligand 10
EXP
CTD Direct Evidence: therapeutic
CTD
PMID:11739529
NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497
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CXCL14
C-X-C motif chemokine ligand 14
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:38614205
NCBI chr 5:135,570,679...135,578,991
Ensembl chr 5:135,570,679...135,579,279
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CYP1A1
cytochrome P450 family 1 subfamily A member 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:33814510
NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
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CYP1A2
cytochrome P450 family 1 subfamily A member 2
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28762043
NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607
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CYP1B1
cytochrome P450 family 1 subfamily B member 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:33814510
NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902
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CYP27B1
cytochrome P450 family 27 subfamily B member 1
ISO
mRNA, protein:decreased expression:kidney (mouse)
RGD
PMID:26476181
RGD:25671412
NCBI chr12:57,762,334...57,767,078
Ensembl chr12:57,762,334...57,768,986
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CYP2A6
cytochrome P450 family 2 subfamily A member 6
EXP ISO
CTD Direct Evidence: marker/mechanism CTD Direct Evidence: therapeutic
CTD
PMID:21741958 PMID:23628428
NCBI chr19:40,843,541...40,850,447
Ensembl chr19:40,843,541...40,850,447
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CYP2B6
cytochrome P450 family 2 subfamily B member 6
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28762043 PMID:33814510
NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398
G
CYP2C18
cytochrome P450 family 2 subfamily C member 18
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr10:94,683,729...94,736,190
Ensembl chr10:94,683,729...94,736,190
G
CYP2C19
cytochrome P450 family 2 subfamily C member 19
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:12963435 PMID:28762043
NCBI chr10:94,762,681...94,855,547
Ensembl chr10:94,762,681...94,855,547
G
CYP2C9
cytochrome P450 family 2 subfamily C member 9
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:14971821 PMID:21741958 PMID:28762043 PMID:33814510
NCBI chr10:94,938,658...94,990,091
Ensembl chr10:94,938,658...94,990,091
G
CYP2D6
cytochrome P450 family 2 subfamily D member 6
IAGP
DNA:hypermethylation:promoter
RGD
PMID:27490558
RGD:14700879
NCBI chr22:42,126,499...42,130,810
Ensembl chr22:42,126,499...42,130,865
G
CYP2E1
cytochrome P450 family 2 subfamily E member 1
treatment
EXP ISO IAGP IMP
CTD Direct Evidence: marker/mechanism DNA:hypermethylation:promoter associated with Endotoxemia
CTD RGD
PMID:12668988 PMID:16770646 PMID:21741958 PMID:28762043 PMID:27960551 PMID:27490558 PMID:27324775 PMID:29404441 PMID:25681370 More...
RGD:14700901 , RGD:14700879 , RGD:14700878 , RGD:14700873 , RGD:14700872
NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220
G
CYP3A4
cytochrome P450 family 3 subfamily A member 4
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28762043
NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248
G
CYP8B1
cytochrome P450 family 8 subfamily B member 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25448281
NCBI chr 3:42,872,192...42,875,879
Ensembl chr 3:42,856,005...42,875,898
G
DBT
dihydrolipoamide branched chain transacylase E2
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 1:100,186,919...100,249,834
Ensembl chr 1:100,186,919...100,249,834
G
DDB1
damage specific DNA binding protein 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr11:61,299,451...61,333,105
Ensembl chr11:61,299,451...61,342,596
G
DGAT2
diacylglycerol O-acyltransferase 2
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:17984051
NCBI chr11:75,768,778...75,801,534
Ensembl chr11:75,759,512...75,801,535
G
DHFR
dihydrofolate reductase
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:19648163
NCBI chr 5:80,626,226...80,654,983
Ensembl chr 5:80,626,226...80,654,983
G
DHRS7
dehydrogenase/reductase 7
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr14:60,144,119...60,169,889
Ensembl chr14:60,144,119...60,169,856
G
DLAT
dihydrolipoamide S-acetyltransferase
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr11:112,025,408...112,064,404
Ensembl chr11:112,025,033...112,064,404
G
DNAJB9
DnaJ heat shock protein family (Hsp40) member B9
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:26881866
NCBI chr 7:108,569,874...108,574,850
Ensembl chr 7:108,569,867...108,574,850
G
DNAJC12
DnaJ heat shock protein family (Hsp40) member C12
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:26881866
NCBI chr10:67,796,669...67,838,188
Ensembl chr10:67,796,669...67,838,188
G
DSC2
desmocollin 2
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr18:31,058,840...31,102,421
Ensembl chr18:31,058,545...31,102,600
G
E2F1
E2F transcription factor 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:30515189
NCBI chr20:33,675,477...33,686,385
Ensembl chr20:33,675,477...33,686,385
G
ECHDC1
ethylmalonyl-CoA decarboxylase 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 6:127,288,712...127,343,609
Ensembl chr 6:127,288,712...127,343,609
G
ECHS1
enoyl-CoA hydratase, short chain 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr10:133,362,485...133,373,354
Ensembl chr10:133,362,485...133,373,354
G
EDEM1
ER degradation enhancing alpha-mannosidase like protein 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 3:5,187,707...5,219,958
Ensembl chr 3:5,187,646...5,219,958
G
EIF2AK1
eukaryotic translation initiation factor 2 alpha kinase 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25411909
NCBI chr 7:6,022,247...6,059,175
Ensembl chr 7:6,022,247...6,059,175
G
EIF4EBP2
eukaryotic translation initiation factor 4E binding protein 2
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr10:70,404,145...70,428,618
Ensembl chr10:70,404,145...70,428,618
G
ENDOG
endonuclease G
ISO
protein:decreased expression:mitochondrion:
RGD
PMID:22509279
RGD:9685364
NCBI chr 9:128,818,500...128,822,676
Ensembl chr 9:128,818,500...128,822,676
G
ENG
endoglin
ISO
protein:increased expression:liver (rat)
RGD
PMID:21146604
RGD:7257529
NCBI chr 9:127,815,016...127,854,658
Ensembl chr 9:127,811,130...127,854,773
G
ENO1
enolase 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:16099942 PMID:25231249
NCBI chr 1:8,861,000...8,878,686
Ensembl chr 1:8,861,000...8,879,190
G
ENPP2
ectonucleotide pyrophosphatase/phosphodiesterase 2
ISO
protein:increased activity:serum:
RGD
PMID:17850827
RGD:9685426
NCBI chr 8:119,557,086...119,673,390
Ensembl chr 8:119,557,086...119,673,453
G
EPHX1
epoxide hydrolase 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 1:225,810,124...225,845,563
Ensembl chr 1:225,810,124...225,845,563
G
ERLEC1
endoplasmic reticulum lectin 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:26881866
NCBI chr 2:53,787,044...53,818,796
Ensembl chr 2:53,787,009...53,833,038
G
ERN1
endoplasmic reticulum to nucleus signaling 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:30538632
NCBI chr17:64,039,142...64,130,144
Ensembl chr17:64,039,080...64,130,819
G
F13A1
coagulation factor XIII A chain
ISO
RGD
PMID:22019897
RGD:11041813
NCBI chr 6:6,144,084...6,320,662
Ensembl chr 6:6,144,084...6,321,013
G
F2RL3
F2R like thrombin or trypsin receptor 3
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:20974703
NCBI chr19:16,888,999...16,892,606
Ensembl chr19:16,888,999...16,892,606
G
F3
coagulation factor III, tissue factor
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:22407844
NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759
G
FADD
Fas associated via death domain
treatment
ISO
RGD
PMID:26062544 PMID:25447754
RGD:11341803 , RGD:10053709
NCBI chr11:70,203,296...70,207,390
Ensembl chr11:70,203,296...70,207,390
G
FADS1
fatty acid desaturase 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr11:61,799,627...61,817,003
Ensembl chr11:61,799,627...61,829,318
G
FADS2
fatty acid desaturase 2
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr11:61,816,203...61,867,354
Ensembl chr11:61,792,980...61,867,354
G
FAS
Fas cell surface death receptor
ISO
protein:increased expression:liver (rat)
RGD
PMID:16831245
RGD:8662853
NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605
G
FASN
fatty acid synthase
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr17:82,078,338...82,098,236
Ensembl chr17:82,078,338...82,098,294
G
FCMR
Fc mu receptor
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 1:206,903,317...206,923,196
Ensembl chr 1:206,903,317...206,923,247
G
FGA
fibrinogen alpha chain
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:20974703
NCBI chr 4:154,583,126...154,590,742
Ensembl chr 4:154,583,126...154,590,742
G
FGF21
fibroblast growth factor 21
severity
ISO
mRNA:increased expression:liver (rat)
RGD
PMID:29883717
RGD:15045603
NCBI chr19:48,755,524...48,758,330
Ensembl chr19:48,755,524...48,758,333
G
FLT1
fms related receptor tyrosine kinase 1
EXP
CTD Direct Evidence: therapeutic
CTD
PMID:21135413
NCBI chr13:28,300,346...28,495,128
Ensembl chr13:28,300,346...28,495,145
G
FMO3
flavin containing dimethylaniline monoxygenase 3
EXP
CTD Direct Evidence: therapeutic
CTD
PMID:24973094
NCBI chr 1:171,090,905...171,117,819
Ensembl chr 1:171,090,901...171,117,819
G
FTL
ferritin light chain
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr19:48,965,309...48,966,879
Ensembl chr19:48,965,309...48,966,879
G
G6PC1
glucose-6-phosphatase catalytic subunit 1
ISO
mRNA:decreased expression:liver (mouse)
RGD
PMID:28189721
RGD:14695531
NCBI chr17:42,900,799...42,914,438
Ensembl chr17:42,900,797...42,914,438
G
G6PD
glucose-6-phosphate dehydrogenase
treatment
ISO
RGD
PMID:21864513
RGD:10449168
NCBI chr X:154,531,390...154,547,569
Ensembl chr X:154,517,825...154,547,572
G
GADD45A
growth arrest and DNA damage inducible alpha
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:20623750
NCBI chr 1:67,685,201...67,688,334
Ensembl chr 1:67,685,201...67,688,334
G
GANAB
glucosidase II alpha subunit
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr11:62,624,829...62,646,613
Ensembl chr11:62,624,826...62,646,726
G
GC
GC vitamin D binding protein
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:16099942
NCBI chr 4:71,741,693...71,805,520
Ensembl chr 4:71,741,696...71,804,041
G
GCLC
glutamate-cysteine ligase catalytic subunit
ISO EXP
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:19481141 PMID:17573345
RGD:10402383
NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970
G
GCLM
glutamate-cysteine ligase modifier subunit
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 1:93,885,199...93,909,430
Ensembl chr 1:93,885,199...93,909,456
G
GDA
guanine deaminase
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 9:72,114,608...72,259,869
Ensembl chr 9:72,114,595...72,257,193
G
GDI1
GDP dissociation inhibitor 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr X:154,437,154...154,443,467
Ensembl chr X:154,436,913...154,443,467
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GFER
growth factor, augmenter of liver regeneration
treatment
IDA ISO
RGD
PMID:22033404 PMID:15968720
RGD:9685722 , RGD:9685727
NCBI chr16:1,984,193...1,987,749
Ensembl chr16:1,984,193...1,987,749
G
GGH
gamma-glutamyl hydrolase
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:21219404
NCBI chr 8:63,015,079...63,038,806
Ensembl chr 8:63,014,881...63,039,407
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GGT1
gamma-glutamyltransferase 1
ISO
RGD
PMID:10934156
RGD:14701049
NCBI chr22:24,583,750...24,628,996
Ensembl chr22:24,594,811...24,629,005
G
GHRL
ghrelin and obestatin prepropeptide
EXP
CTD Direct Evidence: therapeutic
CTD
PMID:34151639
NCBI chr 3:10,285,666...10,292,947
Ensembl chr 3:10,285,666...10,292,947
G
GLUD1
glutamate dehydrogenase 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:33483742
NCBI chr10:87,050,202...87,094,843
Ensembl chr10:87,050,202...87,094,843
G
GOT1
glutamic-oxaloacetic transaminase 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr10:99,396,870...99,430,624
Ensembl chr10:99,396,870...99,430,624
G
GPD1
glycerol-3-phosphate dehydrogenase 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr12:50,104,008...50,111,313
Ensembl chr12:50,103,982...50,111,313
G
GPT
glutamic--pyruvic transaminase
treatment
EXP ISO
CTD Direct Evidence: marker/mechanism protein:increased expression, activity:serum:
CTD RGD
PMID:145039 PMID:19481104 PMID:19085960 PMID:19085960 PMID:27293452 PMID:21772750 PMID:28487901 More...
RGD:14975249 , RGD:14975249 , RGD:14975168 , RGD:14975166 , RGD:14975162
NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174
G
GPT2
glutamic--pyruvic transaminase 2
ISO
protein:increased expression, activity:serum:
RGD
PMID:19085960 PMID:19085960
RGD:14975249 , RGD:14975249
NCBI chr16:46,884,362...46,931,289
Ensembl chr16:46,884,362...46,931,289
G
GRK4
G protein-coupled receptor kinase 4
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 4:2,963,571...3,040,760
Ensembl chr 4:2,963,571...3,040,760
G
GSN
gelsolin
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:16099942
NCBI chr 9:121,201,483...121,332,842
Ensembl chr 9:121,207,794...121,332,843
G
GSR
glutathione-disulfide reductase
treatment
ISO EXP
mRNA, protein:increased expression:liver CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:25226513 PMID:28069987 PMID:23554813 PMID:24154663
RGD:7257532 , RGD:10401878
NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
G
GSTA1
glutathione S-transferase alpha 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28412881
NCBI chr 6:52,791,371...52,803,816
Ensembl chr 6:52,791,371...52,803,860
G
GSTA4
glutathione S-transferase alpha 4
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 6:52,977,953...52,995,284
Ensembl chr 6:52,977,948...52,995,304
G
GSTM1
glutathione S-transferase mu 1
no_association
EXP IAGP ISO
CTD Direct Evidence: marker/mechanism protein:increased expression:liver
CTD RGD
PMID:17465707 PMID:18666253 PMID:25501156 PMID:24465778 PMID:24903797 PMID:29523098 PMID:21138988 More...
RGD:14700970 , RGD:14700959 , RGD:14700941 , RGD:14700937 , RGD:7241599
NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039
G
GSTM2
glutathione S-transferase mu 2
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:20623750
NCBI chr 1:109,668,057...109,683,997
Ensembl chr 1:109,668,022...109,709,551
G
GSTM3
glutathione S-transferase mu 3
EXP
CTD Direct Evidence: therapeutic
CTD
PMID:25743375
NCBI chr 1:109,733,937...109,741,038
Ensembl chr 1:109,733,932...109,741,038
G
GSTM4
glutathione S-transferase mu 4
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 1:109,656,099...109,667,727
Ensembl chr 1:109,656,099...109,665,496
G
GSTO1
glutathione S-transferase omega 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr10:104,254,173...104,267,455
Ensembl chr10:104,235,356...104,267,459
G
GSTP1
glutathione S-transferase pi 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:20623750 PMID:25226513
NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656
G
GSTT1
glutathione S-transferase theta 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:18397238 PMID:18666253 PMID:25226513
G
GULOP
gulonolactone (L-) oxidase, pseudogene
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 8:27,577,611...27,589,073
Ensembl chr 8:27,560,274...27,589,073
G
H19
H19 imprinted maternally expressed transcript
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:30515189
NCBI chr11:1,995,176...2,001,266
Ensembl chr11:1,995,166...2,004,552
G
H2AX
H2A.X variant histone
treatment
ISO
RGD
PMID:23265463
RGD:8693741
NCBI chr11:119,093,874...119,095,465
Ensembl chr11:119,093,874...119,095,465
G
HACL1
2-hydroxyacyl-CoA lyase 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:26881866
NCBI chr 3:15,560,699...15,601,569
Ensembl chr 3:15,560,699...15,601,852
G
HADHA
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 2:26,190,635...26,244,632
Ensembl chr 2:26,190,635...26,244,672
G
HAMP
hepcidin antimicrobial peptide
ISO
mRNA:increased expression:hepatocyte
RGD
PMID:24373749
RGD:11041724
NCBI chr19:35,282,528...35,285,143
Ensembl chr19:35,280,716...35,285,143
G
HAO2
hydroxyacid oxidase 2
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 1:119,368,785...119,394,130
Ensembl chr 1:119,368,779...119,394,130
G
HAVCR1
hepatitis A virus cellular receptor 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:20623750
NCBI chr 5:157,029,413...157,069,407
Ensembl chr 5:157,026,742...157,069,396
G
HBA1
hemoglobin subunit alpha 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr16:176,680...177,522
Ensembl chr16:176,680...177,522
G
HCP5
HLA complex P5
IAGP
ClinVar Annotator: match by term: Drug-induced liver injury due to flucloxacillin
ClinVar
PMID:11888582 PMID:11943262 PMID:12462283 PMID:15024131 PMID:15247624 PMID:15247625 PMID:18256392 PMID:19483685 More...
NCBI chr 6:31,463,180...31,465,809
Ensembl chr 6:31,463,170...31,478,936
G
HLA-A
major histocompatibility complex, class I, A
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:21570397 PMID:28043905
NCBI chr 6:29,942,532...29,945,870
Ensembl chr 6:29,941,260...29,949,572
G
HLA-B
major histocompatibility complex, class I, B
IAGP EXP
ClinVar Annotator: match by term: Drug-induced liver injury due to flucloxacillin CTD Direct Evidence: marker/mechanism
ClinVar CTD
PMID:11888582 PMID:11943262 PMID:12462283 PMID:15024131 PMID:15247624 PMID:15247625 PMID:18256392 PMID:19483685 More...
NCBI chr 6:31,353,875...31,357,179
Ensembl chr 6:31,353,872...31,367,067
G
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
susceptibility
IAGP
DNA:polymorphism: :HLA-DQA1*0102(human) associated with tuberculosis;DNA:polymorphism: :HLA-DQA1*0102(human)
RGD
PMID:20639878 PMID:12359646
RGD:14398844 , RGD:14401573
NCBI chr 6:32,637,406...32,655,272
Ensembl chr 6:32,628,179...32,647,062
G
HLA-DQB1
major histocompatibility complex, class II, DQ beta 1
susceptibility
EXP IAGP
CTD Direct Evidence: marker/mechanism DNA:polymorphism: :HLA-DQB1*05(human) DNA:polymorphism, haplotype
CTD RGD
PMID:21570397 PMID:25250564 PMID:26959717
RGD:36174016 , RGD:11573514
NCBI chr 6:32,659,467...32,666,657
Ensembl chr 6:32,659,467...32,668,383
G
HLA-DRB1
major histocompatibility complex, class II, DR beta 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:21570397
NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,577,902...32,589,848
G
HMGB1
high mobility group box 1
treatment
EXP ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:19783637 PMID:29091898
RGD:15090820
NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597
G
HMOX1
heme oxygenase 1
treatment
ISO EXP
CTD Direct Evidence: marker/mechanism|therapeutic
CTD RGD
PMID:18227147 PMID:22688006 PMID:22886620 PMID:29091898
RGD:10762620 , RGD:15090820
NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
G
HPD
4-hydroxyphenylpyruvate dioxygenase
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:16099942 PMID:22872058
NCBI chr12:121,839,527...121,888,611
Ensembl chr12:121,839,527...121,863,596
G
HPRT1
hypoxanthine phosphoribosyltransferase 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr X:134,460,165...134,500,668
Ensembl chr X:134,460,165...134,520,513
G
HPX
hemopexin
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:16099942
NCBI chr11:6,431,049...6,440,987
Ensembl chr11:6,431,049...6,442,617
G
HRH2
histamine receptor H2
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:22926047
NCBI chr 5:175,658,071...175,710,756
Ensembl chr 5:175,658,030...175,710,756
G
HSPA5
heat shock protein family A (Hsp70) member 5
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382
G
HSPA8
heat shock protein family A (Hsp70) member 8
ISO
protein:altered localization:liver (rat)
RGD
PMID:12376827
RGD:10059389
NCBI chr11:123,057,489...123,062,462
Ensembl chr11:123,057,489...123,063,230
G
ICAM1
intercellular adhesion molecule 1
treatment
ISO
RGD
PMID:29091898
RGD:15090820
NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
G
IDH2
isocitrate dehydrogenase (NADP(+)) 2
severity
ISO
RGD
PMID:31121248
RGD:14985250
NCBI chr15:90,083,045...90,102,468
Ensembl chr15:90,083,045...90,102,477
G
IDO2
indoleamine 2,3-dioxygenase 2
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:32289347
NCBI chr 8:39,934,651...40,016,392
Ensembl chr 8:39,934,614...40,016,392
G
IFNA2
interferon alpha 2
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:1670585
NCBI chr 9:21,384,255...21,385,398
Ensembl chr 9:21,384,255...21,385,398
G
IFNG
interferon gamma
EXP ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:12153990 PMID:21245496 PMID:30013034
RGD:14975100
NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
G
IGF1
insulin like growth factor 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:23639586 PMID:25226513
NCBI chr12:102,395,874...102,481,839
Ensembl chr12:102,395,874...102,481,744
G
IL11
interleukin 11
EXP
CTD Direct Evidence: therapeutic
CTD
PMID:11421492
NCBI chr19:55,364,382...55,370,463
Ensembl chr19:55,364,382...55,370,463
G
IL12B
interleukin 12B
EXP
CTD Direct Evidence: therapeutic
CTD
PMID:36520315
NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,863
G
IL17A
interleukin 17A
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:19633216 PMID:24949944
NCBI chr 6:52,186,375...52,190,638
Ensembl chr 6:52,186,375...52,190,638
G
IL18
interleukin 18
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:19164858
NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096
G
IL1A
interleukin 1 alpha
EXP
CTD Direct Evidence: therapeutic
CTD
PMID:8218930
NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
G
IL1B
interleukin 1 beta
treatment
ISO EXP
CTD Direct Evidence: marker/mechanism|therapeutic
CTD RGD
PMID:19164858 PMID:28138970 PMID:23102243 PMID:29091898 PMID:31342809 PMID:31077717 PMID:29278859 More...
RGD:7204421 , RGD:15090820 , RGD:15036799 , RGD:14975281 , RGD:13793380
NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
G
IL1R2
interleukin 1 receptor type 2
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:17984051
NCBI chr 2:101,991,960...102,028,544
Ensembl chr 2:101,991,960...102,028,544
G
IL22
interleukin 22
EXP
CTD Direct Evidence: therapeutic
CTD
PMID:15122762 PMID:16212920 PMID:23375450
NCBI chr12:68,248,242...68,253,604
Ensembl chr12:68,248,242...68,253,604
G
IL4
interleukin 4
EXP
CTD Direct Evidence: marker/mechanism|therapeutic
CTD
PMID:21094227 PMID:21735453 PMID:22107450
NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678
G
IL6
interleukin 6
treatment
EXP ISO
CTD Direct Evidence: therapeutic
CTD RGD
PMID:7532385 PMID:15763341 PMID:29091898
RGD:15090820
NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
G
IMMT
inner membrane mitochondrial protein
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 2:86,143,936...86,195,462
Ensembl chr 2:86,143,932...86,195,472
G
IRAK1
interleukin 1 receptor associated kinase 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr X:154,010,507...154,019,902
Ensembl chr X:154,010,506...154,019,902
G
ITPR1
inositol 1,4,5-trisphosphate receptor type 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 3:4,493,348...4,847,506
Ensembl chr 3:4,493,345...4,847,506
G
JUND
JunD proto-oncogene, AP-1 transcription factor subunit
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:30515189
NCBI chr19:18,279,694...18,281,622
Ensembl chr19:18,279,694...18,281,622
G
KEAP1
kelch like ECH associated protein 1
ISO
RGD
PMID:18417483
RGD:6893370
NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558
G
KITLG
KIT ligand
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:12594235
NCBI chr12:88,492,793...88,580,471
Ensembl chr12:88,492,793...88,580,851
G
KNG1
kininogen 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:20362651 PMID:30685357
NCBI chr 3:186,717,359...186,744,410
Ensembl chr 3:186,717,348...186,744,410
G
KRT18
keratin 18
ISO EXP
mRNA, protein:increased expression:liver (mouse) CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:19783637 PMID:33483742 PMID:38521541 PMID:17340120
RGD:18337498
NCBI chr12:52,948,855...52,952,906
Ensembl chr12:52,948,871...52,952,906
G
KRT8
keratin 8
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr12:52,897,191...52,949,860
Ensembl chr12:52,897,187...52,949,954
G
LAP3
leucine aminopeptidase 3
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 4:17,577,198...17,607,970
Ensembl chr 4:17,577,198...17,607,972
G
LBP
lipopolysaccharide binding protein
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr20:38,346,482...38,377,013
Ensembl chr20:38,346,482...38,377,013
G
LCAT
lecithin-cholesterol acyltransferase
ISO
mRNA:decreased expression:liver (rat)
RGD
PMID:28959666
RGD:401794432
NCBI chr16:67,939,750...67,944,120
Ensembl chr16:67,939,750...67,944,131
G
LCN2
lipocalin 2
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:20362651 PMID:20623750
NCBI chr 9:128,149,453...128,153,453
Ensembl chr 9:128,149,071...128,153,453
G
LDLR
low density lipoprotein receptor
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:36108984
NCBI chr19:11,089,463...11,133,820
Ensembl chr19:11,089,418...11,133,820
G
LGALS3
galectin 3
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:22461450
NCBI chr14:55,129,252...55,145,430
Ensembl chr14:55,124,110...55,145,423
G
LIPC
lipase C, hepatic type
ISO
mRNA:decreased expression:liver (rat)
RGD
PMID:28959666
RGD:401794432
NCBI chr15:58,431,991...58,569,844
Ensembl chr15:58,410,569...58,569,844
G
LPL
lipoprotein lipase
treatment
ISO
RGD
PMID:27071702
RGD:13794380
NCBI chr 8:19,939,253...19,967,259
Ensembl chr 8:19,901,717...19,967,259
G
LRAT
lecithin retinol acyltransferase
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 4:154,740,838...154,753,120
Ensembl chr 4:154,626,945...154,753,120
G
LTB4R
leukotriene B4 receptor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28487374
NCBI chr14:24,311,502...24,318,036
Ensembl chr14:24,311,450...24,318,036
G
LTF
lactotransferrin
EXP
CTD Direct Evidence: therapeutic
CTD
PMID:16141546
NCBI chr 3:46,435,645...46,485,234
Ensembl chr 3:46,435,645...46,485,234
G
MALAT1
metastasis associated lung adenocarcinoma transcript 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:30515189
NCBI chr11:65,497,738...65,506,516
Ensembl chr11:65,497,640...65,508,073
G
MAP1LC3B
microtubule associated protein 1 light chain 3 beta
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr16:87,392,336...87,404,774
Ensembl chr16:87,383,953...87,404,779
G
MAP3K5
mitogen-activated protein kinase kinase kinase 5
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:18700144
NCBI chr 6:136,557,046...136,793,091
Ensembl chr 6:136,557,046...136,793,097
G
MAT1A
methionine adenosyltransferase 1A
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr10:80,271,820...80,289,658
Ensembl chr10:80,271,820...80,289,658
G
MCCC1
methylcrotonyl-CoA carboxylase subunit 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 3:183,015,218...183,116,196
Ensembl chr 3:183,015,218...183,116,075
G
MDH1
malate dehydrogenase 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:16099942
NCBI chr 2:63,588,963...63,607,197
Ensembl chr 2:63,588,609...63,607,197
G
ME1
malic enzyme 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 6:83,210,402...83,431,051
Ensembl chr 6:83,210,402...83,431,051
G
MED1
mediator complex subunit 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:16109766
NCBI chr17:39,404,285...39,451,263
Ensembl chr17:39,404,285...39,451,272
G
MIR1-1
microRNA 1-1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:30125006
NCBI chr20:62,554,306...62,554,376
Ensembl chr20:62,554,306...62,554,376
G
MIR100
microRNA 100
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr11:122,152,229...122,152,308
Ensembl chr11:122,152,229...122,152,308
G
MIR103A1
microRNA 103a-1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22363424
NCBI chr 5:168,560,896...168,560,973
Ensembl chr 5:168,560,896...168,560,973
G
MIR106B
microRNA 106b
IEP IDA
miRNA:decreased expression:liver (rat) DNA:hypermethylation:promoter
RGD
PMID:29554950 PMID:29554950
RGD:15042854 , RGD:15042854
NCBI chr 7:100,093,993...100,094,074
Ensembl chr 7:100,093,993...100,094,074
G
MIR107
microRNA 107
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25359176 PMID:28545106
NCBI chr10:89,592,747...89,592,827
Ensembl chr10:89,592,747...89,592,827
G
MIR10A
microRNA 10a
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:22363424
NCBI chr17:48,579,838...48,579,947
Ensembl chr17:48,579,838...48,579,947
G
MIR10B
microRNA 10b
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:22363424
NCBI chr 2:176,150,303...176,150,412
Ensembl chr 2:176,150,303...176,150,412
G
MIR122
microRNA 122
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:22045675 PMID:22363424 PMID:25359176 PMID:25527335 PMID:26489516 PMID:28545106 PMID:28844483 PMID:33483742 More...
NCBI chr18:58,451,074...58,451,158
Ensembl chr18:58,451,074...58,451,158
G
MIR1246
microRNA 1246
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr 2:176,600,980...176,601,052
Ensembl chr 2:176,600,980...176,601,052
G
MIR1247
microRNA 1247
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr14:101,560,287...101,560,422
Ensembl chr14:101,560,287...101,560,422
G
MIR1249
microRNA 1249
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr22:45,200,954...45,201,019
Ensembl chr22:45,200,954...45,201,019
G
MIR125B1
microRNA 125b-1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr11:122,099,757...122,099,844
Ensembl chr11:122,099,757...122,099,844
G
MIR125B2
microRNA 125b-2
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr21:16,590,237...16,590,325
Ensembl chr21:16,590,237...16,590,325
G
MIR1260A
microRNA 1260a
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr14:77,266,218...77,266,290
Ensembl chr14:77,266,218...77,266,290
G
MIR1260B
microRNA 1260b
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr11:96,341,438...96,341,526
Ensembl chr11:96,341,438...96,341,526
G
MIR1273H
microRNA 1273h
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr16:24,203,116...24,203,231
Ensembl chr16:24,203,116...24,203,231
G
MIR1285-1
microRNA 1285-1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr 7:92,204,015...92,204,098
Ensembl chr 7:92,204,015...92,204,098
G
MIR1290
microRNA 1290
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr 1:18,897,071...18,897,148
Ensembl chr 1:18,897,071...18,897,148
G
MIR1291
microRNA 1291
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr12:48,654,444...48,654,530
Ensembl chr12:48,654,444...48,654,530
G
MIR1303
microRNA 1303
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr 5:154,685,776...154,685,861
Ensembl chr 5:154,685,776...154,685,861
G
MIR1304
microRNA 1304
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr11:93,733,674...93,733,764
Ensembl chr11:93,733,674...93,733,764
G
MIR1306
microRNA 1306
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr22:20,086,058...20,086,142
Ensembl chr22:20,086,058...20,086,142
G
MIR1307
microRNA 1307
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr10:103,394,253...103,394,401
Ensembl chr10:103,394,253...103,394,401
G
MIR130A
microRNA 130a
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25359176 PMID:28545106
NCBI chr11:57,641,198...57,641,286
Ensembl chr11:57,641,198...57,641,286
G
MIR130B
microRNA 130b
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr22:21,653,304...21,653,385
Ensembl chr22:21,653,304...21,653,385
G
MIR132
microRNA 132
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:22363424
NCBI chr17:2,049,908...2,050,008
Ensembl chr17:2,049,908...2,050,008
G
MIR1343
microRNA 1343
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr11:34,941,837...34,941,920
Ensembl chr11:34,941,837...34,941,920
G
MIR141
microRNA 141
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:22363424 PMID:28545106
NCBI chr12:6,964,097...6,964,191
Ensembl chr12:6,964,097...6,964,191
G
MIR142
microRNA 142
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr17:58,331,232...58,331,318
Ensembl chr17:58,331,232...58,331,318
G
MIR143
microRNA 143
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:30125006
NCBI chr 5:149,428,918...149,429,023
Ensembl chr 5:149,428,918...149,429,023
G
MIR1468
microRNA 1468
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr X:63,786,002...63,786,087
Ensembl chr X:63,786,002...63,786,087
G
MIR148A
microRNA 148a
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25359176 PMID:28545106
NCBI chr 7:25,949,919...25,949,986
Ensembl chr 7:25,949,919...25,949,986
G
MIR149
microRNA 149
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:22363424
NCBI chr 2:240,456,001...240,456,089
Ensembl chr 2:240,456,001...240,456,089
G
MIR150
microRNA 150
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr19:49,500,785...49,500,868
Ensembl chr19:49,500,785...49,500,868
G
MIR151B
microRNA 151b
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr14:100,109,419...100,109,514
Ensembl chr14:100,109,419...100,109,514
G
MIR152
microRNA 152
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr17:48,037,161...48,037,247
Ensembl chr17:48,037,161...48,037,247
G
MIR155
microRNA 155
treatment
ISO
RGD
PMID:29420849 PMID:26867493 PMID:27673475
RGD:21409750 , RGD:25671474 , RGD:25671463
NCBI chr21:25,573,980...25,574,044
Ensembl chr21:25,573,980...25,574,044
G
MIR17
microRNA 17
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr13:91,350,605...91,350,688
Ensembl chr13:91,350,605...91,350,688
G
MIR181C
microRNA 181c
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:22363424
NCBI chr19:13,874,699...13,874,808
Ensembl chr19:13,874,699...13,874,808
G
MIR188
microRNA 188
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr X:50,003,503...50,003,588
Ensembl chr X:50,003,503...50,003,588
G
MIR18A
microRNA 18a
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr13:91,350,751...91,350,821
Ensembl chr13:91,350,751...91,350,821
G
MIR191
microRNA 191
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr 3:49,020,618...49,020,709
Ensembl chr 3:49,020,618...49,020,709
G
MIR192
microRNA 192
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:22045675 PMID:25359176 PMID:28483554 PMID:28545106
NCBI chr11:64,891,137...64,891,246
Ensembl chr11:64,891,137...64,891,246
G
MIR193A
microRNA 193a
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr17:31,559,996...31,560,083
Ensembl chr17:31,559,996...31,560,083
G
MIR193B
microRNA 193b
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr16:14,303,967...14,304,049
Ensembl chr16:14,303,967...14,304,049
G
MIR194-1
microRNA 194-1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28844483
NCBI chr 1:220,118,157...220,118,241
Ensembl chr 1:220,118,157...220,118,241
G
MIR19A
microRNA 19a
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:22363424
NCBI chr13:91,350,891...91,350,972
Ensembl chr13:91,350,891...91,350,972
G
MIR200C
microRNA 200c
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:22363424
NCBI chr12:6,963,699...6,963,766
Ensembl chr12:6,963,699...6,963,766
G
MIR203B
microRNA 203b
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:32659284
NCBI chr14:104,117,418...104,117,503
Ensembl chr14:104,117,418...104,117,503
G
MIR21
microRNA 21
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr17:59,841,266...59,841,337
Ensembl chr17:59,841,266...59,841,337
G
MIR210
microRNA 210
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr11:568,089...568,198
Ensembl chr11:568,089...568,198
G
MIR217
microRNA 217
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:22363424
NCBI chr 2:55,982,967...55,983,076
Ensembl chr 2:55,982,967...55,983,076
G
MIR218-1
microRNA 218-1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:22363424 PMID:30125006
NCBI chr 4:20,528,275...20,528,384
Ensembl chr 4:20,528,275...20,528,384
G
MIR22
microRNA 22
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25359176 PMID:28545106
NCBI chr17:1,713,903...1,713,987
Ensembl chr17:1,713,903...1,713,987
G
MIR221
microRNA 221
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr X:45,746,157...45,746,266
Ensembl chr X:45,746,157...45,746,266
G
MIR222
microRNA 222
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr X:45,747,015...45,747,124
Ensembl chr X:45,747,015...45,747,124
G
MIR223
microRNA 223
ISO
RNA:increased expression:serum,liver
RGD
PMID:28646120
RGD:21408574
NCBI chr X:66,018,870...66,018,979
Ensembl chr X:66,018,870...66,018,979
G
MIR23A
microRNA 23a
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr19:13,836,587...13,836,659
Ensembl chr19:13,836,587...13,836,659
G
MIR23B
microRNA 23b
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr 9:95,085,208...95,085,304
Ensembl chr 9:95,085,208...95,085,304
G
MIR27B
microRNA 27b
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25359176 PMID:28545106
NCBI chr 9:95,085,445...95,085,541
Ensembl chr 9:95,085,445...95,085,541
G
MIR29B2
microRNA 29b-2
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:22363424
NCBI chr 1:207,802,443...207,802,523
Ensembl chr 1:207,802,443...207,802,523
G
MIR29C
microRNA 29c
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106 PMID:30515189
NCBI chr 1:207,801,852...207,801,939
Ensembl chr 1:207,801,852...207,801,939
G
MIR301A
microRNA 301a
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr17:59,151,136...59,151,221
Ensembl chr17:59,151,136...59,151,221
G
MIR30A
microRNA 30a
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:22363424 PMID:25359176 PMID:28545106
NCBI chr 6:71,403,551...71,403,621
Ensembl chr 6:71,403,551...71,403,621
G
MIR30B
microRNA 30b
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr 8:134,800,520...134,800,607
Ensembl chr 8:134,800,520...134,800,607
G
MIR30C1
microRNA 30c-1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22363424
NCBI chr 1:40,757,284...40,757,372
Ensembl chr 1:40,757,284...40,757,372
G
MIR320A
microRNA 320a
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106 PMID:30125006
NCBI chr 8:22,244,966...22,245,037
Ensembl chr 8:22,244,962...22,245,043
G
MIR328
microRNA 328
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr16:67,202,321...67,202,395
Ensembl chr16:67,202,321...67,202,395
G
MIR335
microRNA 335
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr 7:130,496,111...130,496,204
Ensembl chr 7:130,496,111...130,496,204
G
MIR337
microRNA 337
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:22363424
NCBI chr14:100,874,493...100,874,585
Ensembl chr14:100,874,493...100,874,585
G
MIR338
microRNA 338
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr17:81,125,883...81,125,949
Ensembl chr17:81,125,883...81,125,949
G
MIR33B
microRNA 33b
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr17:17,813,836...17,813,931
Ensembl chr17:17,813,836...17,813,931
G
MIR342
microRNA 342
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr14:100,109,655...100,109,753
Ensembl chr14:100,109,655...100,109,753
G
MIR345
microRNA 345
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr14:100,307,859...100,307,956
Ensembl chr14:100,307,859...100,307,956
G
MIR34A
microRNA 34a
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr 1:9,151,668...9,151,777
Ensembl chr 1:9,151,668...9,151,777
G
MIR34C
microRNA 34c
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:22363424
NCBI chr11:111,513,439...111,513,515
Ensembl chr11:111,513,439...111,513,515
G
MIR3591
microRNA 3591
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr18:58,451,080...58,451,152
Ensembl chr18:58,451,080...58,451,152
G
MIR361
microRNA 361
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr X:85,903,636...85,903,707
Ensembl chr X:85,903,636...85,903,707
G
MIR3615
microRNA 3615
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr17:74,748,613...74,748,699
Ensembl chr17:74,748,613...74,748,699
G
MIR362
microRNA 362
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr X:50,008,964...50,009,028
Ensembl chr X:50,008,964...50,009,028
G
MIR367
microRNA 367
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:22363424
NCBI chr 4:112,647,874...112,647,941
Ensembl chr 4:112,647,874...112,647,941
G
MIR378A
microRNA 378a
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr 5:149,732,825...149,732,890
Ensembl chr 5:149,732,825...149,732,890
G
MIR378C
microRNA 378c
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr10:130,962,588...130,962,668
Ensembl chr10:130,962,588...130,962,668
G
MIR378I
microRNA 378i
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr22:41,923,222...41,923,297
Ensembl chr22:41,923,222...41,923,297
G
MIR410
microRNA 410
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:22363424
NCBI chr14:101,065,912...101,065,991
Ensembl chr14:101,065,912...101,065,991
G
MIR421
microRNA 421
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr X:74,218,377...74,218,461
Ensembl chr X:74,218,377...74,218,461
G
MIR423
microRNA 423
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr17:30,117,079...30,117,172
Ensembl chr17:30,117,079...30,117,172
G
MIR4433B
microRNA 4433b
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr 2:64,340,747...64,340,848
Ensembl chr 2:64,340,747...64,340,848
G
MIR4448
microRNA 4448
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr 3:183,886,800...183,886,885
Ensembl chr 3:183,886,800...183,886,885
G
MIR4492
microRNA 4492
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr11:118,910,708...118,910,787
Ensembl chr11:118,910,708...118,910,787
G
MIR4507
microRNA 4507
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr14:105,858,124...105,858,175
Ensembl chr14:105,858,124...105,858,175
G
MIR4516
microRNA 4516
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr16:2,133,119...2,133,204
Ensembl chr16:2,133,119...2,133,204
G
MIR452
microRNA 452
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr X:151,959,628...151,959,712
Ensembl chr X:151,959,628...151,959,712
G
MIR455
microRNA 455
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr 9:114,209,434...114,209,529
Ensembl chr 9:114,209,434...114,209,529
G
MIR483
microRNA 483
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr11:2,134,134...2,134,209
Ensembl chr11:2,134,134...2,134,209
G
MIR484
microRNA 484
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr16:15,643,294...15,643,372
Ensembl chr16:15,643,294...15,643,372
G
MIR497
microRNA 497
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr17:7,017,911...7,018,022
Ensembl chr17:7,017,911...7,018,022
G
MIR499A
microRNA 499a
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr20:34,990,376...34,990,497
Ensembl chr20:34,990,376...34,990,497
G
MIR503
microRNA 503
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:22363424
NCBI chr X:134,546,328...134,546,398
Ensembl chr X:134,546,328...134,546,398
G
MIR505
microRNA 505
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr X:139,924,148...139,924,231
Ensembl chr X:139,924,148...139,924,231
G
MIR5196
microRNA 5196
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr19:35,345,513...35,345,627
Ensembl chr19:35,345,513...35,345,627
G
MIR532
microRNA 532
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr X:50,003,148...50,003,238
Ensembl chr X:50,003,148...50,003,238
G
MIR5588
microRNA 5588
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr 3:185,253,210...185,253,272
Ensembl chr 3:185,253,210...185,253,272
G
MIR574
microRNA 574
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr 4:38,868,032...38,868,127
Ensembl chr 4:38,868,032...38,868,127
G
MIR589
microRNA 589
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr 7:5,495,819...5,495,917
Ensembl chr 7:5,495,819...5,495,917
G
MIR592
microRNA 592
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:22363424 PMID:28545106
NCBI chr 7:127,058,088...127,058,184
Ensembl chr 7:127,058,088...127,058,184
G
MIR625
microRNA 625
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr14:65,471,102...65,471,186
Ensembl chr14:65,471,102...65,471,186
G
MIR627
microRNA 627
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr15:42,199,570...42,199,666
Ensembl chr15:42,199,570...42,199,666
G
MIR629
microRNA 629
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr15:70,079,372...70,079,468
Ensembl chr15:70,079,372...70,079,468
G
MIR651
microRNA 651
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr X:8,126,965...8,127,061
Ensembl chr X:8,126,965...8,127,061
G
MIR660
microRNA 660
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr X:50,013,241...50,013,337
Ensembl chr X:50,013,241...50,013,337
G
MIR6741
microRNA 6741
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr 1:225,922,080...225,922,142
Ensembl chr 1:225,922,080...225,922,142
G
MIR6815
microRNA 6815
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr21:45,478,266...45,478,326
Ensembl chr21:45,478,266...45,478,326
G
MIR6852
microRNA 6852
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr 9:35,710,676...35,710,741
Ensembl chr 9:35,710,676...35,710,741
G
MIR744
microRNA 744
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:22363424 PMID:28545106
NCBI chr17:12,081,899...12,081,996
Ensembl chr17:12,081,899...12,081,996
G
MIR764
microRNA 764
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:22363424
NCBI chr X:114,639,435...114,639,519
Ensembl chr X:114,639,435...114,639,519
G
MIR766
microRNA 766
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr X:119,646,738...119,646,848
Ensembl chr X:119,646,738...119,646,848
G
MIR7704
microRNA 7704
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr 2:176,188,843...176,188,901
Ensembl chr 2:176,188,843...176,188,901
G
MIR7977
microRNA 7977
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr 3:176,515,103...176,515,151
Ensembl chr 3:176,515,103...176,515,151
G
MIR877
microRNA 877
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:27713024
NCBI chr 6:30,584,332...30,584,417
Ensembl chr 6:30,584,332...30,584,417
G
MIR885
microRNA 885
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr 3:10,394,489...10,394,562
Ensembl chr 3:10,394,489...10,394,562
G
MIR93
microRNA 93
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr 7:100,093,768...100,093,847
Ensembl chr 7:100,093,768...100,093,847
G
MIR99A
microRNA 99a
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr21:16,539,089...16,539,169
Ensembl chr21:16,539,089...16,539,169
G
MIRLET7B
microRNA let-7b
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106 PMID:30125006
NCBI chr22:46,113,686...46,113,768
Ensembl chr22:46,113,686...46,113,768
G
MIRLET7C
microRNA let-7c
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr21:16,539,828...16,539,911
Ensembl chr21:16,539,828...16,539,911
G
MIRLET7D
microRNA let-7d
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr 9:94,178,834...94,178,920
Ensembl chr 9:94,178,834...94,178,920
G
MIRLET7G
microRNA let-7g
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr 3:52,268,278...52,268,361
Ensembl chr 3:52,268,278...52,268,361
G
MIRLET7I
microRNA let-7i
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28545106
NCBI chr12:62,603,686...62,603,769
Ensembl chr12:62,603,686...62,603,769
G
MMP2
matrix metallopeptidase 2
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:15763341
NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691
G
MMP9
matrix metallopeptidase 9
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:22507835
NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561
G
MST1
macrophage stimulating 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 3:49,683,947...49,689,474
Ensembl chr 3:49,683,947...49,689,501
G
MST1R
macrophage stimulating 1 receptor
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:22575169
NCBI chr 3:49,887,002...49,903,873
Ensembl chr 3:49,886,902...49,903,873
G
MT-ND6
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6
ISO
mRNA:decreased expression:blood
RGD
PMID:20130021
RGD:8657129
NCBI chr MT:14,149...14,673
Ensembl chr MT:14,149...14,673
G
MTHFR
methylenetetrahydrofolate reductase
treatment
EXP IAGP
CTD Direct Evidence: marker/mechanism associated with precursor lymphoblastic lymphoma/leukemia; DNA:SNP: :677C>T(human)
CTD RGD
PMID:18551038 PMID:19648163 PMID:30545275
RGD:14696733
NCBI chr 1:11,785,723...11,805,964
Ensembl chr 1:11,785,723...11,806,455
G
MTPN
myotrophin
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 7:135,926,760...135,977,359
Ensembl chr 7:135,926,760...135,977,359
G
MYD88
MYD88 innate immune signal transduction adaptor
ameliorates
ISO
RGD
PMID:17615358
RGD:150521532
NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,552...38,143,024
G
NAT2
N-acetyltransferase 2
treatment
IAGP EXP
associated with Tuberculosis;DNA:haplotype: : CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:11915035 PMID:16799928 PMID:17950035 PMID:25693865 PMID:18023090
RGD:8552665
NCBI chr 8:18,386,301...18,401,218
Ensembl chr 8:18,391,282...18,401,218
G
NDUFS3
NADH:ubiquinone oxidoreductase core subunit S3
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr11:47,579,074...47,584,562
Ensembl chr11:47,565,336...47,584,562
G
NFATC4
nuclear factor of activated T cells 4
EXP
CTD Direct Evidence: therapeutic
CTD
PMID:34192554
NCBI chr14:24,366,911...24,379,604
Ensembl chr14:24,365,673...24,379,604
G
NFE2L2
NFE2 like bZIP transcription factor 2
treatment
ISO EXP
induced by methotrexate (CHEBI:44185), treated by ferulic acid (CHEBI:17620) CTD Direct Evidence: therapeutic
CTD RGD
PMID:22491424 PMID:22627062 PMID:24813929 PMID:26958860 PMID:30215777 PMID:18417483 PMID:31889292 PMID:31927046 PMID:32066295 PMID:31972209 PMID:29091898 More...
RGD:6893370 , RGD:21201308 , RGD:21201305 , RGD:21201283 , RGD:21201280 , RGD:15090820
NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756
G
NFKB1
nuclear factor kappa B subunit 1
treatment susceptibility
ISO IAGP
associated with tuberculosis ;DNA:SNPs,haplotypes: 3'utr,5'utr: (rs78872571,rs4647992) (human)
RGD
PMID:29091898 PMID:31490979
RGD:15090820 , RGD:40902984
NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302
G
NFXL1
nuclear transcription factor, X-box binding like 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:26881866
NCBI chr 4:47,847,233...47,914,667
Ensembl chr 4:47,847,233...47,914,667
G
NME2
NME/NM23 nucleoside diphosphate kinase 2
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr17:51,165,536...51,171,744
Ensembl chr17:51,165,435...51,171,744
G
NOTCH1
notch receptor 1
EXP
CTD Direct Evidence: therapeutic
CTD
PMID:30394310
NCBI chr 9:136,494,433...136,546,048
Ensembl chr 9:136,494,433...136,546,048
G
NOX4
NADPH oxidase 4
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr11:89,324,353...89,589,557
Ensembl chr11:89,324,353...89,498,187
G
NQO1
NAD(P)H quinone dehydrogenase 1
treatment
ISO
RGD
PMID:28522909 PMID:29091898 PMID:28472605
RGD:13439737 , RGD:15090820 , RGD:13439739
NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668
G
NR0B2
nuclear receptor subfamily 0 group B member 2
EXP
CTD Direct Evidence: therapeutic
CTD
PMID:29943110
NCBI chr 1:26,911,489...26,913,975
Ensembl chr 1:26,911,489...26,913,975
G
NR1D1
nuclear receptor subfamily 1 group D member 1
treatment
ISO
RGD
PMID:24497272
RGD:10448995
NCBI chr17:40,092,793...40,100,589
Ensembl chr17:40,092,793...40,100,589
G
NR1H3
nuclear receptor subfamily 1 group H member 3
EXP
CTD Direct Evidence: therapeutic
CTD
PMID:17256725
NCBI chr11:47,248,300...47,269,033
Ensembl chr11:47,248,300...47,269,033
G
NR1H4
nuclear receptor subfamily 1 group H member 4
treatment severity
EXP ISO
CTD Direct Evidence: marker/mechanism mRNA:decreased expression:liver (rat) protein:decreased expression:liver (rat)
CTD RGD
PMID:12875239 PMID:29091898 PMID:28827769 PMID:30068870 PMID:22711662 PMID:20573685 More...
RGD:15090820 , RGD:15045609 , RGD:15042870 , RGD:14701036 , RGD:14701035
NCBI chr12:100,473,866...100,564,414
Ensembl chr12:100,473,708...100,564,414
G
NR1I2
nuclear receptor subfamily 1 group I member 2
susceptibility
EXP IAGP
CTD Direct Evidence: marker/mechanism|therapeutic associated with tuberculosis ;DNA:SNP,haplotypes:promoter: (rs3814055) (human)
CTD RGD
PMID:19797606 PMID:28058446 PMID:31490979
RGD:40902984
NCBI chr 3:119,782,101...119,818,487
Ensembl chr 3:119,780,484...119,818,487
G
NR1I3
nuclear receptor subfamily 1 group I member 3
EXP
CTD Direct Evidence: marker/mechanism|therapeutic
CTD
PMID:14742670 PMID:25656644 PMID:28058446
NCBI chr 1:161,229,669...161,238,203
Ensembl chr 1:161,229,666...161,238,244
G
NR2F2
nuclear receptor subfamily 2 group F member 2
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr15:96,326,046...96,340,263
Ensembl chr15:96,325,938...96,340,263
G
NR5A2
nuclear receptor subfamily 5 group A member 2
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:29515023
NCBI chr 1:200,027,710...200,177,415
Ensembl chr 1:200,027,614...200,177,420
G
NREP
neuronal regeneration related protein
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 5:111,728,802...111,976,932
Ensembl chr 5:111,662,621...111,997,464
G
NTN1
netrin 1
EXP
CTD Direct Evidence: therapeutic
CTD
PMID:35292334
NCBI chr17:9,003,087...9,244,000
Ensembl chr17:9,021,510...9,244,000
G
NUS1
NUS1 dehydrodolichyl diphosphate synthase subunit
EXP
CTD Direct Evidence: therapeutic
CTD
PMID:33812996
NCBI chr 6:117,675,469...117,710,727
Ensembl chr 6:117,675,469...117,710,727
G
OCIAD1
OCIA domain containing 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 4:48,805,156...48,861,815
Ensembl chr 4:48,805,212...48,861,817
G
OGDH
oxoglutarate dehydrogenase
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 7:44,606,627...44,709,066
Ensembl chr 7:44,606,572...44,709,066
G
OR51E2
olfactory receptor family 51 subfamily E member 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr11:4,680,171...4,697,853
Ensembl chr11:4,680,171...4,697,854
G
P4HB
prolyl 4-hydroxylase subunit beta
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr17:81,843,166...81,860,535
Ensembl chr17:81,843,159...81,860,856
G
PAH
phenylalanine hydroxylase
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr12:102,836,889...102,958,441
Ensembl chr12:102,836,889...102,958,410
G
PAN2
poly(A) specific ribonuclease subunit PAN2
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:26881866
NCBI chr12:56,316,936...56,334,000
Ensembl chr12:56,316,223...56,334,053
G
PANX1
pannexin 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:29246445
NCBI chr11:94,128,841...94,181,968
Ensembl chr11:94,128,841...94,181,968
G
PARK7
Parkinsonism associated deglycase
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 1:7,961,711...7,985,505
Ensembl chr 1:7,954,291...7,985,505
G
PC
pyruvate carboxylase
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr11:66,848,420...66,958,383
Ensembl chr11:66,848,417...66,958,386
G
PCOLCE
procollagen C-endopeptidase enhancer
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 7:100,602,363...100,608,175
Ensembl chr 7:100,602,363...100,608,175
G
PCYT1A
phosphate cytidylyltransferase 1A, choline
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 3:196,234,368...196,287,726
Ensembl chr 3:196,214,222...196,287,957
G
PDK4
pyruvate dehydrogenase kinase 4
EXP
CTD Direct Evidence: marker/mechanism|therapeutic
CTD
PMID:21182459 PMID:31809757
NCBI chr 7:95,583,499...95,596,516
Ensembl chr 7:95,583,499...95,596,516
G
PDLIM5
PDZ and LIM domain 5
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 4:94,451,942...94,668,223
Ensembl chr 4:94,451,857...94,668,227
G
PEX11A
peroxisomal biogenesis factor 11 alpha
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr15:89,681,535...89,690,754
Ensembl chr15:89,677,764...89,690,783
G
PGM1
phosphoglucomutase 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 1:63,593,411...63,660,245
Ensembl chr 1:63,593,411...63,660,245
G
PLAT
plasminogen activator, tissue type
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:22507835
NCBI chr 8:42,174,718...42,207,565
Ensembl chr 8:42,174,718...42,207,709
G
PLG
plasminogen
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:22507835
NCBI chr 6:160,702,193...160,754,097
Ensembl chr 6:160,702,194...160,754,097
G
PLS3
plastin 3
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr X:115,561,174...115,650,861
Ensembl chr X:115,561,174...115,650,861
G
PNP
purine nucleoside phosphorylase
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:16099942
NCBI chr14:20,469,406...20,477,089
Ensembl chr14:20,461,992...20,477,094
G
PNRC1
proline rich nuclear receptor coactivator 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 6:89,080,751...89,085,160
Ensembl chr 6:89,080,751...89,085,160
G
POLG
DNA polymerase gamma, catalytic subunit
susceptibility no_association
EXP IAGP
CTD Direct Evidence: marker/mechanism DNA:missense mutation:cds:p.W748S, p.E1143G (2243G>C, 3428A>G) (human) DNA:missense mutations:cds:p.Q1236H, p.E1143G (33708G>T, 3428A>G) (human)
CTD RGD
PMID:18208989 PMID:20138553 PMID:25065347 PMID:30255931
RGD:15039302 , RGD:15039297
NCBI chr15:89,316,320...89,334,824
Ensembl chr15:89,305,198...89,334,861
G
POLR2G
RNA polymerase II subunit G
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr11:62,761,580...62,766,710
Ensembl chr11:62,761,565...62,766,710
G
PON1
paraoxonase 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:16099942
NCBI chr 7:95,297,676...95,324,532
Ensembl chr 7:95,297,676...95,324,532
G
PPARA
peroxisome proliferator activated receptor alpha
ISO EXP
LPS-induced acute liver damage CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:24385052 PMID:38181850 PMID:21262334
RGD:5509941
NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755
G
PPARG
peroxisome proliferator activated receptor gamma
ISO
mRNA, protein:decreased expression:liver
RGD
PMID:26599535
RGD:11554658
NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
G
PPTC7
protein phosphatase targeting COQ7
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr12:110,533,245...110,583,318
Ensembl chr12:110,533,245...110,583,318
G
PRKAA1
protein kinase AMP-activated catalytic subunit alpha 1
treatment
ISO
RGD
PMID:29091898
RGD:15090820
NCBI chr 5:40,759,389...40,798,374
Ensembl chr 5:40,759,389...40,798,374
G
PRKCD
protein kinase C delta
EXP
CTD Direct Evidence: therapeutic
CTD
PMID:30393195
NCBI chr 3:53,161,209...53,192,717
Ensembl chr 3:53,156,009...53,192,717
G
PRKDC
protein kinase, DNA-activated, catalytic subunit
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:21224054
NCBI chr 8:47,773,111...47,960,136
Ensembl chr 8:47,773,111...47,960,178
G
PTF1A
pancreas associated transcription factor 1a
EXP
CTD Direct Evidence: therapeutic
CTD
PMID:21182459
NCBI chr10:23,192,312...23,194,245
Ensembl chr10:23,192,312...23,194,245
G
PTGES2
prostaglandin E synthase 2
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:31444509
NCBI chr 9:128,120,693...128,128,440
Ensembl chr 9:128,120,693...128,128,462
G
PTGS2
prostaglandin-endoperoxide synthase 2
treatment
EXP ISO
CTD Direct Evidence: therapeutic
CTD RGD
PMID:11743745 PMID:29091898
RGD:15090820
NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
G
PUM1
pumilio RNA binding family member 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 1:30,931,506...31,065,717
Ensembl chr 1:30,931,506...31,065,991
G
PYGL
glycogen phosphorylase L
EXP IEP
CTD Direct Evidence: marker/mechanism protein:increased expression:serum (rat)
CTD RGD
PMID:25231249 PMID:25336395
RGD:21079733
NCBI chr14:50,905,217...50,944,483
Ensembl chr14:50,857,891...50,944,483
G
PZP
PZP alpha-2-macroglobulin like
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:16099942
NCBI chr12:9,136,472...9,208,395
Ensembl chr12:9,148,840...9,208,395
G
RASA1
RAS p21 protein activator 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 5:87,267,883...87,391,916
Ensembl chr 5:87,267,883...87,391,931
G
RBP1
retinol binding protein 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:16099942
NCBI chr 3:139,517,438...139,539,742
Ensembl chr 3:139,517,434...139,539,829
G
RDH13
retinol dehydrogenase 13
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:27865848
NCBI chr19:55,039,103...55,069,520
Ensembl chr19:55,039,108...55,071,291
G
REEP5
receptor accessory protein 5
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:26881866
NCBI chr 5:112,876,385...112,922,227
Ensembl chr 5:112,876,385...112,922,289
G
RGN
regucalcin
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr X:47,078,443...47,093,313
Ensembl chr X:47,078,355...47,093,314
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RIPK3
receptor interacting serine/threonine kinase 3
EXP ISO
CTD Direct Evidence: therapeutic protein:increased expression:liver (mouse)
CTD RGD
PMID:26769846 PMID:28205631
RGD:127229945
NCBI chr14:24,336,025...24,339,991
Ensembl chr14:24,336,025...24,340,022
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S100A11
S100 calcium binding protein A11
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 1:152,032,506...152,037,004
Ensembl chr 1:152,032,506...152,047,907
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SCARB1
scavenger receptor class B member 1
ISO
mRNA:increased expression:liver (rat)
RGD
PMID:28959666
RGD:401794432
NCBI chr12:124,776,856...124,863,864
Ensembl chr12:124,776,856...124,882,668
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SELENBP1
selenium binding protein 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:20623750
NCBI chr 1:151,364,304...151,372,705
Ensembl chr 1:151,364,304...151,372,707
G
SEMA3A
semaphorin 3A
EXP
CTD Direct Evidence: therapeutic
CTD
PMID:33290778
NCBI chr 7:83,955,777...84,492,725
Ensembl chr 7:83,955,777...84,492,724
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SEMA4A
semaphorin 4A
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:33290778
NCBI chr 1:156,147,373...156,177,744
Ensembl chr 1:156,147,366...156,177,752
G
SENP2
SUMO specific peptidase 2
EXP
CTD Direct Evidence: therapeutic
CTD
PMID:29535048
NCBI chr 3:185,586,295...185,633,551
Ensembl chr 3:185,582,496...185,633,551
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SERPINA1
serpin family A member 1
susceptibility
ISO IAGP
protein:decreased expression:plasma DNA:missense mutation:cds:p.E264V(human)
RGD
PMID:11140575 PMID:20170533
RGD:1643168 , RGD:14695048
NCBI chr14:94,376,747...94,390,635
Ensembl chr14:94,376,747...94,390,693
G
SERPINA6
serpin family A member 6
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr14:94,304,248...94,323,336
Ensembl chr14:94,304,248...94,323,389
G
SERPINE1
serpin family E member 1
treatment
IAGP
associated with precursor lymphoblastic lymphoma/leukemia;DNA:SNPs: :DNA:SNPs: :677C>T, 1298A>C(human)
RGD
PMID:23183238
RGD:14696750
NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247
G
SERPING1
serpin family G member 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr11:57,597,685...57,614,848
Ensembl chr11:57,597,387...57,619,171
G
SESN2
sestrin 2
EXP
CTD Direct Evidence: therapeutic
CTD
PMID:28209544
NCBI chr 1:28,259,518...28,282,491
Ensembl chr 1:28,259,518...28,282,491
G
SGF29
SAGA complex associated factor 29
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr16:28,553,920...28,591,790
Ensembl chr16:28,553,915...28,591,790
G
SHC1
SHC adaptor protein 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249 PMID:32659284
NCBI chr 1:154,962,298...154,974,376
Ensembl chr 1:154,962,298...154,974,395
G
SLC10A1
solute carrier family 10 member 1
ISO
mRNA:decreased expression:liver (rat)
RGD
PMID:28827769
RGD:15045609
NCBI chr14:69,775,416...69,797,241
Ensembl chr14:69,775,416...69,797,241
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SLC10A7
solute carrier family 10 member 7
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:26881866
NCBI chr 4:146,253,981...146,521,940
Ensembl chr 4:146,253,975...146,522,372
G
SLC13A4
solute carrier family 13 member 4
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 7:135,681,231...135,728,186
Ensembl chr 7:135,681,231...135,729,258
G
SLC22A8
solute carrier family 22 member 8
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr11:62,992,824...63,015,841
Ensembl chr11:62,989,154...63,015,841
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SLC25A29
solute carrier family 25 member 29
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr14:100,278,567...100,306,444
Ensembl chr14:100,291,116...100,306,547
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SLC7A5
solute carrier family 7 member 5
treatment
ISO
RGD
PMID:9200186
RGD:151357001
NCBI chr16:87,830,023...87,869,507
Ensembl chr16:87,830,023...87,869,507
G
SLCO1B1
solute carrier organic anion transporter family member 1B1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:32259555
NCBI chr12:21,131,194...21,239,796
Ensembl chr12:21,131,194...21,239,796
G
SLPI
secretory leukocyte peptidase inhibitor
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:17984051
NCBI chr20:45,252,239...45,254,564
Ensembl chr20:45,252,239...45,254,564
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SNX18
sorting nexin 18
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:17984051
NCBI chr 5:54,517,759...54,648,005
Ensembl chr 5:54,517,759...54,546,586
G
SOD1
superoxide dismutase 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:20623750 PMID:27349771
NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931
G
SOD2
superoxide dismutase 2
treatment severity susceptibility
EXP IAGP ISO
CTD Direct Evidence: marker/mechanism associated with acute lymphoblastic leukemia;DNA:SNP: :(rs4880)(human) DNA:SNP:cds:p.Val16Ala(human)
CTD RGD
PMID:25226513 PMID:27019981 PMID:19647030 PMID:19332662 PMID:20578157
RGD:11060605 , RGD:26923961 , RGD:26923959 , RGD:26923957
NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
G
SOD3
superoxide dismutase 3
EXP
CTD Direct Evidence: therapeutic
CTD
PMID:11529661
NCBI chr 4:24,795,573...24,800,842
Ensembl chr 4:24,789,912...24,800,842
G
SORD
sorbitol dehydrogenase
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:12763371
NCBI chr15:45,023,195...45,077,185
Ensembl chr15:45,023,147...45,077,185
G
SORL1
sortilin related receptor 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:26881866
NCBI chr11:121,452,314...121,633,763
Ensembl chr11:121,452,314...121,633,763
G
SPIN2A
spindlin family member 2A
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:16099942
NCBI chr X:57,134,265...57,147,180
Ensembl chr X:57,134,530...57,137,523
G
SPP1
secreted phosphoprotein 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:20623750
NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532
G
SRP72
signal recognition particle 72
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:26881866
NCBI chr 4:56,467,617...56,503,681
Ensembl chr 4:56,467,617...56,503,681
G
STAT3
signal transducer and activator of transcription 3
EXP
CTD Direct Evidence: therapeutic
CTD
PMID:38460807
NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568
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STAT4
signal transducer and activator of transcription 4
severity
ISO
protein:increased phosphorylation:liver, inflammatory cell (mouse) mRNA:increased expression:liver, macrophage (mouse)
RGD
PMID:24731448 PMID:23876342
RGD:25671417 , RGD:25671422
NCBI chr 2:191,029,576...191,151,596
Ensembl chr 2:191,029,576...191,178,435
G
STING1
stimulator of interferon response cGAMP interactor 1
EXP
CTD Direct Evidence: therapeutic
CTD
PMID:36520315
NCBI chr 5:139,475,533...139,482,758
Ensembl chr 5:139,475,533...139,482,935
G
SULT1C3
sulfotransferase family 1C member 3
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 2:108,239,968...108,265,351
Ensembl chr 2:108,239,968...108,265,351
G
SULT1E1
sulfotransferase family 1E member 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 4:69,821,122...69,860,145
Ensembl chr 4:69,841,212...69,860,145
G
SULT2B1
sulfotransferase family 2B member 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:27052460
NCBI chr19:48,552,172...48,599,427
Ensembl chr19:48,552,172...48,599,425
G
SUOX
sulfite oxidase
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr12:55,997,276...56,005,525
Ensembl chr12:55,997,180...56,006,641
G
TAGLN2
transgelin 2
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 1:159,918,111...159,925,507
Ensembl chr 1:159,918,107...159,925,507
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TALDO1
transaldolase 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:19436114
NCBI chr11:747,464...765,012
Ensembl chr11:747,415...765,012
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TBXA2R
thromboxane A2 receptor
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:22206755
NCBI chr19:3,594,507...3,606,875
Ensembl chr19:3,594,507...3,606,875
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TCTN1
tectonic family member 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:17984051
NCBI chr12:110,614,129...110,649,430
Ensembl chr12:110,614,027...110,663,431
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TF
transferrin
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:16099942
NCBI chr 3:133,661,998...133,796,641
Ensembl chr 3:133,746,040...133,796,641
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TGFB1
transforming growth factor beta 1
treatment
ISO
RGD
PMID:27516150
RGD:14995464
NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
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TGFBR1
transforming growth factor beta receptor 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:28560358
NCBI chr 9:99,103,647...99,154,192
Ensembl chr 9:99,104,038...99,154,192
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THBS1
thrombospondin 1
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:35357534
NCBI chr15:39,581,079...39,599,466
Ensembl chr15:39,581,079...39,599,466
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THPO
thrombopoietin
EXP
CTD Direct Evidence: therapeutic
CTD
PMID:33122006
NCBI chr 3:184,371,935...184,379,688
Ensembl chr 3:184,371,935...184,381,968
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TLR4
toll like receptor 4
disease_progression
ISO
RGD
PMID:17504260
RGD:14697733
NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735
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TLR5
toll like receptor 5
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:30508503
NCBI chr 1:223,109,404...223,143,248
Ensembl chr 1:223,109,404...223,143,292
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TLR9
toll like receptor 9
severity treatment
IEP ISO
protein:increased expression: blood, neutrophil (human)
RGD
PMID:26457748 PMID:19164858 PMID:23509352
RGD:18337465 , RGD:18337476 , RGD:18337473
NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,225,645
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TMED7
transmembrane p24 trafficking protein 7
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:26881866
NCBI chr 5:115,613,210...115,626,036
Ensembl chr 5:115,613,210...115,632,992
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TMEM117
transmembrane protein 117
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:26881866
NCBI chr12:43,795,802...44,399,108
Ensembl chr12:43,835,967...44,389,762
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TMEM164
transmembrane protein 164
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr X:110,002,369...110,184,251
Ensembl chr X:110,002,631...110,182,734
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TMEM38B
transmembrane protein 38B
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 9:105,694,541...105,776,629
Ensembl chr 9:105,694,541...105,776,629
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TNF
tumor necrosis factor
treatment severity
ISO EXP
CTD Direct Evidence: marker/mechanism|therapeutic protein:increased expression:serum (rat)
CTD RGD
PMID:7532385 PMID:9696492 PMID:17709330 PMID:19638433 PMID:20623750 PMID:21984482 PMID:37866487 PMID:15830285 PMID:29091898 PMID:31342809 PMID:14686721 PMID:10801288 PMID:10801287 PMID:19189285 PMID:17070847 PMID:31077717 PMID:11124822 More...
RGD:10450531 , RGD:15090820 , RGD:15036799 , RGD:14995485 , RGD:14995437 , RGD:14995435 , RGD:14995430 , RGD:14995429 , RGD:14975281 , RGD:14696804
NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
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TRAJ18
T cell receptor alpha joining 18
EXP
CTD Direct Evidence: therapeutic
CTD
PMID:36520315
NCBI chr14:22,525,650...22,525,715
Ensembl chr14:22,525,650...22,525,715
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TRPM2
transient receptor potential cation channel subfamily M member 2
ISO
RGD
PMID:24569808
RGD:9999438
NCBI chr21:44,353,621...44,442,644
Ensembl chr21:44,350,163...44,443,081
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TTR
transthyretin
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:16099942
NCBI chr18:31,591,877...31,598,821
Ensembl chr18:31,557,009...31,598,833
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TUBA1A
tubulin alpha 1a
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr12:49,184,795...49,189,080
Ensembl chr12:49,184,686...49,189,324
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TUBB4B
tubulin beta 4B class IVb
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 9:137,241,287...137,243,707
Ensembl chr 9:137,241,287...137,243,707
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UBA5
ubiquitin like modifier activating enzyme 5
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:26881866
NCBI chr 3:132,654,430...132,679,794
Ensembl chr 3:132,654,446...132,679,794
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UGT1A1
UDP glucuronosyltransferase family 1 member A1
susceptibility
IAGP
DNA:SNP:exon (rs4148323)(human)
RGD
PMID:28900877
RGD:14694824
NCBI chr 2:233,760,270...233,773,300
Ensembl chr 2:233,760,270...233,773,300
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UGT1A9
UDP glucuronosyltransferase family 1 member A9
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:20623750
NCBI chr 2:233,671,898...233,773,300
Ensembl chr 2:233,671,898...233,773,300
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UNC93B1
unc-93 homolog B1, TLR signaling regulator
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr11:67,991,100...68,004,097
Ensembl chr11:67,991,100...68,004,982
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USP5
ubiquitin specific peptidase 5
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr12:6,852,150...6,866,632
Ensembl chr12:6,852,148...6,866,632
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VEGFA
vascular endothelial growth factor A
treatment
EXP IDA
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:25231249 PMID:17784864
RGD:15003197
NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487
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VIM
vimentin
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593
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VWF
von Willebrand factor
ISO EXP
protein:increased expression:liver: CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:28527913 PMID:7531171
RGD:11079232
NCBI chr12:5,948,877...6,124,670
Ensembl chr12:5,948,877...6,124,770
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WASL
WASP like actin nucleation promoting factor
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 7:123,681,943...123,749,003
Ensembl chr 7:123,681,943...123,749,003
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XRCC1
X-ray repair cross complementing 1
susceptibility
ISO
DNA:haploinsufficiency: : (mouse)
RGD
PMID:21737425
RGD:15036796
NCBI chr19:43,543,311...43,575,527
Ensembl chr19:43,543,311...43,580,473
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XYLB
xylulokinase
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25231249
NCBI chr 3:38,346,785...38,453,041
Ensembl chr 3:38,346,760...38,421,348
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ZDHHC23
zinc finger DHHC-type palmitoyltransferase 23
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chr 3:113,947,901...113,979,508
Ensembl chr 3:113,947,901...113,965,401
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ABCC2
ATP binding cassette subfamily C member 2
susceptibility no_association
IAGP
DNA:polymorphisms,haplotype:promoter:g.-1774delG,g.-1549G>A(human) DNA:SNPs:multiple:
RGD
PMID:17502832 PMID:22178260
RGD:14700816 , RGD:14700817
NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594
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CYP2E1
cytochrome P450 family 2 subfamily E member 1
ISO
DNA:hypermethylation:promoter
RGD
PMID:23619520
RGD:14700910
NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220
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HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase
ISO
RGD
PMID:16140414
RGD:2316848
NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001
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LPAR1
lysophosphatidic acid receptor 1
ISO
protein:increased expression:liver (mouse)
RGD
PMID:12201952
RGD:10054288
NCBI chr 9:110,873,263...111,038,998
Ensembl chr 9:110,873,263...111,038,470
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MIR22
microRNA 22
ISO
in male; RNA:increased expression:liver:
RGD
PMID:21750200
RGD:14700876
NCBI chr17:1,713,903...1,713,987
Ensembl chr17:1,713,903...1,713,987
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GPT
glutamic--pyruvic transaminase
treatment
ISO
RGD
PMID:28921207
RGD:14975164
NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174
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