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RGD uses the Human Disease Ontology (DO, for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Cardio-Renal Syndrome
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Accession:DOID:9007325 term browser browse the term
Definition:Condition where a primary dysfunction of either heart or kidney results in failure of the other organ (e.g., HEART FAILURE with worsening RENAL INSUFFICIENCY).
Synonyms:exact_synonym: Cardio-Renal Syndromes;   Cardiorenal Syndrome;   Cardiorenal Syndromes;   Reno Cardiac Syndrome;   Reno-Cardiac Syndromes;   Renocardiac Syndrome;   Renocardiac Syndromes
 primary_id: MESH:D059347;   RDO:0010008
For additional species annotation, visit the Alliance of Genome Resources.

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Cardio-Renal Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Havcr1 hepatitis A virus cellular receptor 1 susceptibility ISO
protein:increased expression:kidney tubule: RGD PMID:23220287, PMID:22367506 RGD:7245477, RGD:7245950 NCBI chr10:31,813,819...31,860,934
Ensembl chr10:31,813,814...31,848,379
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Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16035
    syndrome 7010
      Cardio-Renal Syndrome 1
Path 2
Term Annotations click to browse term
  disease 16035
    disease of anatomical entity 15289
      Urogenital Diseases 4157
        urinary system disease 2075
          kidney disease 1863
            kidney failure 493
              Cardio-Renal Syndrome 1
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.