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RGD uses the Human Disease Ontology (DO, for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Cardio-Renal Syndrome
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Accession:DOID:9007325 term browser browse the term
Definition:Condition where a primary dysfunction of either heart or kidney results in failure of the other organ (e.g., HEART FAILURE with worsening RENAL INSUFFICIENCY).
Synonyms:exact_synonym: Cardio-Renal Syndromes;   Cardiorenal Syndrome;   Cardiorenal Syndromes;   Reno Cardiac Syndrome;   Reno-Cardiac Syndromes;   Renocardiac Syndrome;   Renocardiac Syndromes
 primary_id: MESH:D059347

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Cardio-Renal Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Havcr1 hepatitis A virus cellular receptor 1 susceptibility ISO
protein:increased expression:kidney tubule: RGD PMID:23220287 PMID:22367506 RGD:7245477, RGD:7245950 NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
JBrowse link
G Mir21 microRNA 21 ameliorates IMP RGD PMID:28760335 RGD:41410821 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
JBrowse link
G Myocd myocardin ameliorates ISO
mRNA,protein:increased expression:left ventricle RGD PMID:30971740 PMID:30971740 RGD:401793740, RGD:401793740 NCBI chr10:49,833,219...49,928,806
Ensembl chr10:49,836,641...49,927,627
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 21121
    syndrome 10792
      Cardio-Renal Syndrome 3
Path 2
Term Annotations click to browse term
  disease 21121
    disease of anatomical entity 18204
      Urogenital Diseases 5211
        urinary system disease 2819
          kidney disease 2575
            kidney failure 568
              Cardio-Renal Syndrome 3
paths to the root