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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Experimental Seizures
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Accession:DOID:9007090 term browser browse the term
Definition:Seizures that are induced in experimental animals, often initiated by the injection of a drug, such as kainic acid, pilocarpine, or pentetrazole.
Synonyms:exact_synonym: experimental epilepsy
For additional species annotation, visit the Alliance of Genome Resources.


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Experimental Seizures term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agap2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 ISO RGD PMID:21925531 RGD:13838850 NCBI chr 7:62,897,282...62,914,295
Ensembl chr 7:62,897,282...62,914,295 		JBrowse link
G Becn1 beclin 1 treatment IEP RGD PMID:23994218 RGD:11561923 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Dmd dystrophin IEP RGD PMID:9539217 RGD:12880363 NCBI chr  X:47,272,324...49,504,219
Ensembl chr  X:47,272,331...49,504,207 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 treatment IEP RGD PMID:22038365 RGD:10401935 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Rasgrf1 RAS protein-specific guanine nucleotide-releasing factor 1 IEP protein:decreased expression:dentate gyrus, hippocampus CA1, cerebral cortex (rat) RGD PMID:23200899 RGD:10003135 NCBI chr 8:90,445,154...90,574,274
Ensembl chr 8:90,445,154...90,574,269 		JBrowse link
G Rgs10 regulator of G-protein signaling 10 IEP RGD PMID:12358788 RGD:13524540 NCBI chr 1:182,946,334...182,987,729
Ensembl chr 1:182,946,336...182,987,697 		JBrowse link
G Rgs4 regulator of G-protein signaling 4 IEP RGD PMID:12358788 RGD:13524540 NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068 		JBrowse link
G Rgs7 regulator of G-protein signaling 7 IEP RGD PMID:12358788 RGD:13524540 NCBI chr13:86,979,269...87,408,834
Ensembl chr13:86,979,279...87,408,888 		JBrowse link
G Rgs8 regulator of G-protein signaling 8 IEP RGD PMID:12358788 RGD:13524540 NCBI chr13:65,804,703...65,848,953
Ensembl chr13:65,804,797...65,846,807 		JBrowse link
G Sv2a synaptic vesicle glycoprotein 2a IMP DNA:mutation:cds:p.L174Q(rat) RGD PMID:27265781 RGD:12792961 NCBI chr 2:183,741,455...183,757,290
Ensembl chr 2:183,741,547...183,756,927 		JBrowse link
G Sv2am1Kyo synaptic vesicle glycoprotein 2a; ENU induced mutant 1, Kyo, IMP RGD PMID:27265781 RGD:12792961
G Uqcrfs1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 IEP protein:increased expression:hippocampus RGD PMID:15730530 RGD:2303356 NCBI chr17:33,977,908...33,982,478
Ensembl chr17:33,977,921...33,982,479 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 18133
    Animal Diseases 1692
      Animal Disease Models 1640
        Experimental Seizures 13
Path 2
Term Annotations click to browse term
  disease 18133
    disease of anatomical entity 17503
      nervous system disease 13174
        sensory system disease 6388
          eye disease 2927
            visual pathway disease 628
              visual cortex disease 625
                visual epilepsy 625
                  Experimental Seizures 13
paths to the root