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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Acute Experimental Autoimmune Encephalomyelitis
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Accession:DOID:9006973 term browser browse the term
Definition:An acute version of EAE, an experimental animal model for central nervous system demyelinating disease, in which focal demyelination is mild.
Synonyms:exact_synonym: acute experimental allergic encephalomyelitis
 primary_id: RDO:9000097


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Acute Experimental Autoimmune Encephalomyelitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MAG myelin associated glycoprotein ISO protein:decreased expression:optic nerve RGD PMID:9820787 RGD:9685300 NCBI chr 6:44,794,197...44,809,933
Ensembl chr 6:44,794,204...44,809,926 		JBrowse link
G ZC3H12A zinc finger CCCH-type containing 12A disease_progression ISO RGD PMID:26320658 RGD:11534569 NCBI chr 6:93,541,334...93,551,200
Ensembl chr 6:93,541,334...93,551,193 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 17412
    Animal Diseases 1302
      Animal Disease Models 1255
        Experimental Nervous System Autoimmune Disease 184
          Experimental Autoimmune Encephalomyelitis 157
            Acute Experimental Autoimmune Encephalomyelitis 2
Path 2
Term Annotations click to browse term
  disease 17412
    disease of anatomical entity 14873
      Immune & Inflammatory Diseases 4952
        immune system disease 4289
          primary immunodeficiency disease 3701
            autoimmune disease 1973
              autoimmune disease of the nervous system 553
                autoimmune disease of central nervous system 296
                  Demyelinating Autoimmune Diseases, CNS 289
                    Experimental Autoimmune Encephalomyelitis 157
                      Acute Experimental Autoimmune Encephalomyelitis 2
paths to the root