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Pathways

RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:nephrotoxicity
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Accession:DOID:9006956 term browser browse the term
Definition:This is toxicity that causes injury to the kidney or damages its function. It is a poisonous effect of some substances, both toxic chemicals and medications.
Synonyms:exact_synonym: kidney toxicity;   renal toxicity
 xref: EFO:0011056



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nephrotoxicity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir494 microRNA 494 ISO RGD PMID:25854542 RGD:156420140 NCBI chr 6:128,728,710...128,728,792
Ensembl chr 6:128,728,709...128,728,793
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Term paths to the root
Path 1
Term Annotations click to browse term
  disease 21086
    Pathological Conditions, Signs and Symptoms 13268
      Pathologic Processes 7968
        nephrotoxicity 1
Path 2
Term Annotations click to browse term
  disease 21086
    disease of anatomical entity 18146
      Urogenital Diseases 4934
        urinary system disease 2545
          kidney disease 2304
            nephrotoxicity 1
paths to the root