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ONTOLOGY REPORT - ANNOTATIONS


Term:Lyme Neuroborreliosis
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Accession:DOID:9006939 term browser browse the term
Definition:Nervous system infections caused by tick-borne spirochetes of the BORRELIA BURGDORFERI GROUP. The disease may affect elements of the central or peripheral nervous system in isolation or in combination. Common clinical manifestations include a lymphocytic meningitis, cranial neuropathy (most often a facial neuropathy), POLYRADICULOPATHY, and a mild loss of memory and other cognitive functions. Less often more extensive inflammation involving the central nervous system (encephalomyelitis) may occur. In the peripheral nervous system, B. burgdorferi infection is associated with mononeuritis multiplex and polyradiculoneuritis. (From J Neurol Sci 1998 Jan 8;153(2):182-91)
Synonyms:exact_synonym: Borrelia burgdorferi Neuroborreliosis;   Central Nervous System Lyme Disease;   Lyme Disease Encephalopathies;   Lyme Disease Encephalopathy;   Lyme Disease Mononeuritis Multiplex;   Lyme Meningoencephalitis;   Lyme Meningoradiculitis;   Lyme Polyradiculitides;   Lyme Polyradiculitis;   Lyme Polyradiculopathies;   Lyme Polyradiculopathy;   Nervous System Lyme Borreliosis;   Nervous System Lyme Disease;   Neuroborrelioses, Borrelia burgdorferi;   Peripheral Nervous System Lyme Disease
 primary_id: MESH:D020852
 alt_id: RDO:0007439
For additional species annotation, visit the Alliance of Genome Resources.


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Lyme Neuroborreliosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:11528571
G Cd40 CD40 molecule JBrowse link 3 161,519,789 161,534,943 RGD:11352252
G Cd40lg CD40 ligand JBrowse link X 159,703,703 159,714,886 RGD:11352252
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:7193053

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Path 1
Term Annotations click to browse term
  disease 15609
    disease by infectious agent 835
      Bacterial Infections and Mycoses 576
        bacterial infectious disease 488
          Central Nervous System Bacterial Infections 37
            Lyme Neuroborreliosis 4
Path 2
Term Annotations click to browse term
  disease 15609
    disease by infectious agent 835
      Bacterial Infections and Mycoses 576
        bacterial infectious disease 488
          Spirochaetales Infections 15
            Borrelia Infections 8
              Lyme disease 8
                Lyme Neuroborreliosis 4
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.