RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Nervous system infections caused by tick-borne spirochetes of the BORRELIA BURGDORFERI GROUP. The disease may affect elements of the central or peripheral nervous system in isolation or in combination. Common clinical manifestations include a lymphocytic meningitis, cranial neuropathy (most often a facial neuropathy), POLYRADICULOPATHY, and a mild loss of memory and other cognitive functions. Less often more extensive inflammation involving the central nervous system (encephalomyelitis) may occur. In the peripheral nervous system, B. burgdorferi infection is associated with mononeuritis multiplex and polyradiculoneuritis. (From J Neurol Sci 1998 Jan 8;153(2):182-91)
Synonyms:
exact_synonym:
Borrelia burgdorferi Neuroborreliosis; Central Nervous System Lyme Disease; Lyme Disease Encephalopathies; Lyme Disease Encephalopathy; Lyme Disease Mononeuritis Multiplex; Lyme Meningoencephalitis; Lyme Meningoradiculitis; Lyme Polyradiculitides; Lyme Polyradiculitis; Lyme Polyradiculopathies; Lyme Polyradiculopathy; Nervous System Lyme Borreliosis; Nervous System Lyme Disease; Neuroborrelioses, Borrelia burgdorferi; Peripheral Nervous System Lyme Disease