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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Drug-Related Side Effects and Adverse Reactions
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Accession:DOID:9006810 term browser browse the term
Definition:Disorders that result from the intended use of PHARMACEUTICAL PREPARATIONS. Included in this heading are a broad variety of chemically-induced adverse conditions due to toxicity, DRUG INTERACTIONS, and metabolic effects of pharmaceuticals.
Synonyms:exact_synonym: Adverse Drug Reaction;   Adverse Drug Reactions;   Drug Side Effect;   Drug Side Effects;   Drug Toxicities;   adverse drug event;   adverse drug events;   drug toxicity;   side effects of drugs
 related_synonym: Brain pseudoatrophy, reversible, valproate-induced, susceptibility to
 primary_id: MESH:D064420
For additional species annotation, visit the Alliance of Genome Resources.


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Drug-Related Side Effects and Adverse Reactions term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1 ATP binding cassette subfamily B member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18381794 PMID:20563569 PMID:21064136 PMID:24502637 PMID:25007187 More... NCBI chrNW_004936763:1,225,355...1,308,257 JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18256692 NCBI chrNW_004936501:3,400,971...3,467,061 JBrowse link
G Abcc12 ATP binding cassette subfamily C member 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18466103 NCBI chrNW_004936475:1,331,887...1,391,535 JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20216337 PMID:23222202 PMID:25007187 PMID:32387182 NCBI chrNW_004936636:292,631...341,999 JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23222202 NCBI chrNW_004936472:14,396,986...14,624,597 JBrowse link
G Ache acetylcholinesterase (Cartwright blood group) ISO CTD Direct Evidence: therapeutic CTD PMID:27083141 NCBI chrNW_004936543:856,678...862,080 JBrowse link
G Adora1 adenosine A1 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:15641640 NCBI chrNW_004936567:1,430,128...1,508,626 JBrowse link
G Adora2a adenosine A2a receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:15641640 NCBI chrNW_004936619:597,970...618,564 JBrowse link
G Ahsg alpha 2-HS glycoprotein ISO CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chrNW_004936578:3,332,934...3,339,903 JBrowse link
G Apob apolipoprotein B ISO CTD Direct Evidence: marker/mechanism CTD PMID:31186542 NCBI chrNW_004936493:10,509,118...10,549,144 JBrowse link
G Arid5b AT-rich interaction domain 5B ISO CTD Direct Evidence: marker/mechanism CTD PMID:24712521 NCBI chrNW_004936614:1,072,263...1,252,573 JBrowse link
G Ass1 argininosuccinate synthase 1 ISO protein:increased expression:plasma (rat) RGD PMID:20544730 RGD:4140449 NCBI chrNW_004936487:17,482,307...17,527,407 JBrowse link
G Atic 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16947783 NCBI chrNW_004936586:1,782,581...1,809,458 JBrowse link
G B2m beta-2-microglobulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chrNW_004936471:7,646,504...7,655,656 JBrowse link
G Bche butyrylcholinesterase ISO CTD Direct Evidence: marker/mechanism CTD PMID:3111302 NCBI chrNW_004936707:1,784,338...1,913,401 JBrowse link
G C3 complement C3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chrNW_004936588:3,985,732...4,023,221 JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H ISO CTD Direct Evidence: marker/mechanism CTD PMID:30552955 NCBI chrNW_004936694:2,702,224...2,724,574 JBrowse link
G Camk2n1 calcium/calmodulin dependent protein kinase II inhibitor 1 ISO associated with colon cancer RGD PMID:22020760 RGD:15097511 NCBI chrNW_004936474:6,463,691...6,466,641 JBrowse link
G Cda cytidine deaminase ISO DNA:SNP:cds:rs1048977|rs12726436|rs2072671 (human) RGD PMID:28347776 RGD:152995291 NCBI chrNW_004936474:6,543,295...6,564,575 JBrowse link
G Ces2 carboxylesterase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19931604 NCBI chrNW_004936475:17,452,749...17,460,880 JBrowse link
G Clu clusterin ISO CTD Direct Evidence: marker/mechanism CTD PMID:24361871 PMID:28885000 NCBI chrNW_004936675:499,745...513,515 JBrowse link
G Commd1 copper metabolism domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23583003 NCBI chrNW_004936491:7,247,160...7,421,039 JBrowse link
G Csf2 colony stimulating factor 2 ISO CTD Direct Evidence: therapeutic CTD PMID:7960606 NCBI chrNW_004936647:3,081,896...3,083,864 JBrowse link
G Csf3 colony stimulating factor 3 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:7692001 PMID:27737899 PMID:31557154 NCBI chrNW_004936490:15,142,526...15,146,375 JBrowse link
G Dhfr dihydrofolate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21064136 NCBI chrNW_004936469:67,962...83,116 JBrowse link
G Dip2b disco interacting protein 2 homolog B ISO CTD Direct Evidence: marker/mechanism CTD PMID:31557154 NCBI chrNW_004936512:8,131,304...8,370,519 JBrowse link
G Dpyd dihydropyrimidine dehydrogenase ISO DNA:SNP:cds:rs12119882 (human) RGD PMID:28347776 RGD:152995291 NCBI chrNW_004936537:1,660,461...2,439,305 JBrowse link
G Enosf1 enolase superfamily member 1 ISO DNA:SNP:cds:rs699517 (human) RGD PMID:28347776 RGD:152995291 NCBI chrNW_004936550:12,899...31,390 JBrowse link
G Epha7 EPH receptor A7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30357299 NCBI chrNW_004936812:698,548...865,589 JBrowse link
G Ephx2 epoxide hydrolase 2 ISO CTD Direct Evidence: therapeutic CTD PMID:26165641 NCBI chrNW_004936675:350,357...392,919 JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit treatment ISO associated with Leukemia, Myeloid, Acute
associated with Breast Neoplasms;DNA:SNP: :p.Q504K (human)
RGD PMID:17197435 PMID:25495407 RGD:11252168 RGD:11252178 NCBI chrNW_004936706:1,854,938...1,867,521 JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit treatment ISO DNA:SNP: :p.K751Q (rs13181) (human)
associated with Leukemia, Myeloid, Acute;DNA:SNPs, haplotypes: :p.D312N, p.K751Q (human)
RGD PMID:15339847 PMID:17197435 RGD:11252178 RGD:11252202 NCBI chrNW_004936706:1,816,561...1,829,638 JBrowse link
G Fga fibrinogen alpha chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:15805072 NCBI chrNW_004936576:1,322,406...1,329,743 JBrowse link
G Fndc3b fibronectin type III domain containing 3B ISO CTD Direct Evidence: marker/mechanism CTD PMID:31557154 NCBI chrNW_004936593:311,245...638,625 JBrowse link
G Gata4 GATA binding protein 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31190750 NCBI chrNW_004936675:3,408,549...3,420,828 JBrowse link
G Gata6 GATA binding protein 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31190750 NCBI chrNW_004936550:1,814,336...1,844,399 JBrowse link
G Gc GC vitamin D binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chrNW_004936598:3,220,029...3,256,091 JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15805072 PMID:24361871 PMID:28885000 NCBI chrNW_004936515:6,030,402...6,051,161 JBrowse link
G Hmgb1 high mobility group box 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27474498 NCBI chrNW_004936472:25,236,728...25,246,585 JBrowse link
G Hmox1 heme oxygenase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18227147 NCBI chrNW_004936492:5,042,353...5,049,216 JBrowse link
G Homer1 homer scaffold protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24126708 NCBI chrNW_004936549:7,189,588...7,320,117 JBrowse link
G Hpx hemopexin ISO CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chrNW_004936842:485,515...495,684 JBrowse link
G Hspb6 heat shock protein family B (small) member 6 ISO CTD Direct Evidence: therapeutic CTD PMID:18948619 NCBI chrNW_004936570:568,708...571,099 JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B ISO CTD Direct Evidence: marker/mechanism CTD PMID:16863450 NCBI chrNW_004936525:5,711,894...5,729,074 JBrowse link
G Ifng interferon gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:31557154 NCBI chrNW_004936545:6,139,130...6,144,543 JBrowse link
G Igf1 insulin like growth factor 1 ISO CTD Direct Evidence: therapeutic CTD PMID:20064577 NCBI chrNW_004936492:11,709,623...11,784,028 JBrowse link
G Igfbp1 insulin like growth factor binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15805072 NCBI chrNW_004936478:20,494,190...20,499,001 JBrowse link
G Il10 interleukin 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31557154 NCBI chrNW_004936557:5,834,874...5,838,502 JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO CTD Direct Evidence: marker/mechanism CTD PMID:31557154 NCBI chrNW_004936783:1,447,158...1,466,331 JBrowse link
G Il3 interleukin 3 ISO CTD Direct Evidence: therapeutic CTD PMID:8202718 NCBI chrNW_004936647:3,102,922...3,104,758 JBrowse link
G Il6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31557154 NCBI chrNW_004936549:7,015,595...7,016,246 JBrowse link
G Kitlg KIT ligand ISO CTD Direct Evidence: therapeutic CTD PMID:1720698 NCBI chrNW_004936507:5,566,144...5,650,412 JBrowse link
G Lcn2 lipocalin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chrNW_004936487:15,721,752...15,725,396 JBrowse link
G LOC101961588 cytochrome P450 2D17 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23609392 NCBI chrNW_004936718:153,340...157,966 JBrowse link
G LOC101962856 ceruloplasmin ISO CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chrNW_004936519:6,431,156...6,473,183 JBrowse link
G LOC101964975 interleukin-8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31557154 NCBI chrNW_004936598:1,779,471...1,781,353 JBrowse link
G LOC101969421 cytochrome P450 1A2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10445756 NCBI chrNW_004936471:33,704,616...33,709,455 JBrowse link
G LOC101970831 serotransferrin ISO CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chrNW_004936529:6,917,762...6,947,512 JBrowse link
G LOC101973029 cytochrome P450 2E1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18990727 NCBI chrNW_004936486:19,691,822...19,702,684 JBrowse link
G LOC101976131 alpha-1-microglobulin/bikunin precursor ISO CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chrNW_004936487:3,399,792...3,412,088 JBrowse link
G LOC101976500 haptoglobin ISO CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chrNW_004936475:21,841,054...21,845,821 JBrowse link
G Ltbr lymphotoxin beta receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:31557154 NCBI chrNW_004936709:1,362,846...1,369,287 JBrowse link
G Mapk14 mitogen-activated protein kinase 14 susceptibility ISO associated with lung non-small cell carcinoma;DNA:SNP:3' utr, intron: (rs3804451) (human) RGD PMID:26993769 RGD:151665351 NCBI chrNW_004936476:23,237,762...23,310,211 JBrowse link
G Mocos molybdenum cofactor sulfurase ISO CTD Direct Evidence: marker/mechanism CTD PMID:29935280 NCBI chrNW_004936517:9,059,042...9,105,304 JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:15753437 PMID:16166815 PMID:17387702 PMID:17502830 PMID:18551038 More... NCBI chrNW_004936474:623,438...637,849 JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:15753437 PMID:19159907 NCBI chrNW_004936484:16,087,924...16,180,089 JBrowse link
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21064136 NCBI chrNW_004936643:379,790...410,034 JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 ISO CTD Direct Evidence: therapeutic CTD PMID:20605904 NCBI chrNW_004936509:6,589,967...6,621,171 JBrowse link
G Nr3c1 nuclear receptor subfamily 3 group C member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29802709 NCBI chrNW_004936504:10,960,069...11,056,834 JBrowse link
G Nt5c2 5'-nucleotidase, cytosolic II ISO CTD Direct Evidence: marker/mechanism CTD PMID:31557154 NCBI chrNW_004936600:2,828,277...2,892,795 JBrowse link
G Peli1 pellino E3 ubiquitin protein ligase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31557154 NCBI chrNW_004936491:8,985,074...9,040,863 JBrowse link
G Plg plasminogen ISO CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chrNW_004936489:11,775,243...11,808,482 JBrowse link
G Plk2 polo like kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12897130 NCBI chrNW_004936480:9,680,461...9,686,593 JBrowse link
G Ppara peroxisome proliferator activated receptor alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:19683050 NCBI chrNW_004936629:3,672,445...3,725,645 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10698006 NCBI chrNW_004936481:3,821,564...3,828,086 JBrowse link
G Ren renin ISO CTD Direct Evidence: marker/mechanism CTD PMID:8723173 NCBI chrNW_004936567:598,044...607,628 JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21064136 NCBI chrNW_004936741:1,849,239...1,877,724 JBrowse link
G Slc19a1 solute carrier family 19 member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21064136 NCBI chrNW_004936778:823,376...846,843 JBrowse link
G Slc22a7 solute carrier family 22 member 7 ISO DNA:SNP:cds:rs2270860|rs4149178 (human) RGD PMID:28347776 RGD:152995291 NCBI chrNW_004936476:16,675,377...16,680,209 JBrowse link
G Slc34a2 solute carrier family 34 member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15805072 NCBI chrNW_004936477:3,954,377...3,975,259 JBrowse link
G Slco2a1 solute carrier organic anion transporter family member 2A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15805072 NCBI chrNW_004936529:7,069,003...7,155,229 JBrowse link
G Sod1 superoxide dismutase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chrNW_004936500:10,345,154...10,352,873 JBrowse link
G Spp1 secreted phosphoprotein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15805072 NCBI chrNW_004936905:148,956...156,023 JBrowse link
G Tcn2 transcobalamin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15753437 NCBI chrNW_004936904:97,535...113,886 JBrowse link
G Thbd thrombomodulin ISO CTD Direct Evidence: therapeutic CTD PMID:27474498 NCBI chrNW_004936620:2,563,900...2,568,117 JBrowse link
G Tlr1 toll like receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18466103 NCBI chrNW_004936482:6,582,430...6,591,128 JBrowse link
G Tlr2 toll like receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18466103 PMID:31557154 NCBI chrNW_004936576:522,234...531,660 JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:31557154 NCBI chrNW_004936727:1,936,066...1,937,766 JBrowse link
G Top1 DNA topoisomerase I ISO CTD Direct Evidence: marker/mechanism CTD PMID:19931604 NCBI chrNW_004936561:641,451...723,323 JBrowse link
G Tp53 tumor protein p53 ISO CTD Direct Evidence: marker/mechanism CTD PMID:9369336 NCBI chrNW_004936595:919,807...935,367 JBrowse link
G Ttr transthyretin ISO CTD Direct Evidence: marker/mechanism CTD PMID:28885000 NCBI chrNW_004936682:1,628,489...1,635,495 JBrowse link
G Txn thioredoxin ISO CTD Direct Evidence: therapeutic CTD PMID:11462148 NCBI chrNW_004936559:2,811,786...2,822,528 JBrowse link
G Tyms thymidylate synthetase ISO CTD Direct Evidence: marker/mechanism
DNA:SNP:cds:rs2853741 (human)
CTD
RGD
PMID:19648163 PMID:21064136 PMID:25007187 PMID:26077125 PMID:28347776 RGD:152995291 NCBI chrNW_004936550:33,797...42,233 JBrowse link
G Umps uridine monophosphate synthetase ISO DNA:SNP:cds:rs2279199|rs4678145 (human) RGD PMID:28347776 RGD:152995291 NCBI chrNW_004936725:553,278...564,846 JBrowse link
G Vegfa vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism CTD PMID:31068094 NCBI chrNW_004936476:16,245,134...16,261,180 JBrowse link
G Vkorc1 vitamin K epoxide reductase complex subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26445138 NCBI chrNW_004936501:13,459,400...13,461,864 JBrowse link
Anthracycline-induced Cardiotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1 ATP binding cassette subfamily B member 1 susceptibility ISO DNA:missense mutation:cds:p.G671V (human) RGD PMID:16330681 RGD:11041175 NCBI chrNW_004936763:1,225,355...1,308,257 JBrowse link
G Capn2 calpain 2 treatment ISO RGD PMID:25634181 RGD:13792617 NCBI chrNW_004936526:879,765...932,682 JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit ISO associated with Leukemia, Myeloid, Acute;DNA:SNP:exon:p.K751Q (rs13181) (human) RGD PMID:24284041 RGD:11252190 NCBI chrNW_004936706:1,816,561...1,829,638 JBrowse link
aspirin-induced respiratory disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacng6 calcium voltage-gated channel auxiliary subunit gamma 6 susceptibility ISO DNA:SNP,haplotype:rs192808(human) RGD PMID:20860846 RGD:13524562 NCBI chrNW_004936994:158,621...171,597 JBrowse link
G Ccr3 C-C motif chemokine receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:20022477 PMID:20485159 RGD:4145619 NCBI chrNW_004936596:223,660...224,739 JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16502481 PMID:17641958 PMID:20485159 NCBI chrNW_004936547:479,261...504,757 JBrowse link
G Cysltr2 cysteinyl leukotriene receptor 2 ISO CTD Direct Evidence: marker/mechanism
DNA:SNPs: :-819T>G, 2078C>T, 2534A>G (human)
CTD
RGD
PMID:15970796 PMID:16502481 PMID:20485159 RGD:5144000 NCBI chrNW_004936565:1,917,970...1,919,027 JBrowse link
G Fancc FA complementation group C ISO DNA:haplotype::rs4647416(human) RGD PMID:21670957 RGD:11045795 NCBI chrNW_004936626:3,980,311...4,147,042 JBrowse link
G LOC101963197 HLA class II histocompatibility antigen, DP beta 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:16502481 NCBI chrNW_004936476:25,730,800...25,741,089 JBrowse link
G Ltc4s leukotriene C4 synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:9393345 PMID:9466979 PMID:10970818 PMID:20485159 NCBI chrNW_004936739:975,494...978,426 JBrowse link
G Ms4a2 membrane spanning 4-domains A2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16502481 NCBI chrNW_004936581:2,743,133...2,751,925 JBrowse link
G Postn periostin ISO CTD Direct Evidence: marker/mechanism CTD PMID:18391768 NCBI chrNW_004936472:31,644,778...31,677,572 JBrowse link
G Ptgdr2 prostaglandin D2 receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20485159 NCBI chrNW_004936581:2,069,355...2,072,535 JBrowse link
G Ptger2 prostaglandin E receptor 2 ISO ClinVar Annotator: match by term: Asthma, aspirin-induced, susceptibility to ClinVar PMID:15496426 NCBI chrNW_004936697:2,440,943...2,453,897 JBrowse link
G Ptgir prostaglandin I2 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:20485159 NCBI chrNW_004936664:487,069...489,328 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:mast cell
CTD
RGD
PMID:9487340 PMID:16502481 PMID:20485159 RGD:5143936 NCBI chrNW_004936481:3,821,564...3,828,086 JBrowse link
G Tap2 transporter 2, ATP binding cassette subfamily B member ISO RGD PMID:21796142 RGD:5147839 NCBI chrNW_004936476:25,913,699...25,923,419 JBrowse link
G Tbx21 T-box transcription factor 21 ISO ClinVar Annotator: match by term: Asthma, aspirin-induced, susceptibility to ClinVar PMID:15806396 NCBI chrNW_004936490:13,546,405...13,558,635 JBrowse link
G Tbxa2r thromboxane A2 receptor susceptibility ISO CTD Direct Evidence: marker/mechanism
DNA:polymorphism: :795T>C (human)
CTD
RGD
PMID:15898979 PMID:16502481 PMID:20485159 RGD:11059537 NCBI chrNW_004936588:2,040,712...2,044,635 JBrowse link
asthma, nasal polyps, and aspirin intolerance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox15 arachidonate 15-lipoxygenase ISO ClinVar Annotator: match by term: Asthma, nasal polyps, and aspirin intolerance ClinVar PMID:17959182 PMID:21558275 PMID:30643255 NCBI chrNW_004936677:3,232,183...3,241,307 JBrowse link
G Ptger2 prostaglandin E receptor 2 ISO OMIM NCBI chrNW_004936697:2,440,943...2,453,897 JBrowse link
G Tbx21 T-box transcription factor 21 ISO ClinVar Annotator: match by term: Asthma, nasal polyps, and aspirin intolerance OMIM
ClinVar
PMID:25741868 NCBI chrNW_004936490:13,546,405...13,558,635 JBrowse link
Cardiotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen ISO CTD Direct Evidence: marker/mechanism CTD PMID:33676887 NCBI chrNW_004936484:19,713,299...19,721,144 JBrowse link
G Bche butyrylcholinesterase ISO CTD Direct Evidence: therapeutic CTD PMID:26145887 NCBI chrNW_004936707:1,784,338...1,913,401 JBrowse link
G Bmp2 bone morphogenetic protein 2 ISO CTD Direct Evidence: therapeutic CTD PMID:29800642 NCBI chrNW_004936485:12,428,765...12,439,570 JBrowse link
G Csf1 colony stimulating factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:32068018 NCBI chrNW_004936704:1,372,137...1,393,355 JBrowse link
G Fas Fas cell surface death receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:34713381 NCBI chrNW_004936735:209,369...234,582 JBrowse link
G Faslg Fas ligand ISO CTD Direct Evidence: marker/mechanism CTD PMID:34713381 NCBI chrNW_004936481:14,789,547...14,795,780 JBrowse link
G Hbegf heparin binding EGF like growth factor ISO CTD Direct Evidence: therapeutic CTD PMID:29305325 NCBI chrNW_004936531:9,332,939...9,345,039 JBrowse link
G Il1b interleukin 1 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:32068018 NCBI chrNW_004936783:1,251,678...1,256,807 JBrowse link
G LOC101964975 interleukin-8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29959987 NCBI chrNW_004936598:1,779,471...1,781,353 JBrowse link
G Mettl14 methyltransferase 14, N6-adenosine-methyltransferase subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:34648132 NCBI chrNW_004936869:568,324...589,972 JBrowse link
G Nos3 nitric oxide synthase 3 treatment ISO associated with Precursor Cell Lymphoblastic Leukemia-Lymphoma;DNA:polymorphism: :894G>T(human) RGD PMID:26345518 RGD:11533645 NCBI chrNW_004936527:6,427,147...6,445,770 JBrowse link
G Nppb natriuretic peptide B ISO CTD Direct Evidence: marker/mechanism CTD PMID:29959987 NCBI chrNW_004936474:683,325...684,662 JBrowse link
G Nrg1 neuregulin 1 ISO CTD Direct Evidence: therapeutic CTD PMID:29305325 NCBI chrNW_004936766:1,104,841...1,306,368 JBrowse link
G Rac1 Rac family small GTPase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28710503 NCBI chrNW_004936750:107,689...122,679 JBrowse link
G Rarg retinoic acid receptor gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:26237429 NCBI chrNW_004936512:10,502,954...10,524,796 JBrowse link
G Sirt6 sirtuin 6 ISO CTD Direct Evidence: therapeutic CTD PMID:34713381 NCBI chrNW_004936588:2,387,162...2,394,066 JBrowse link
G Tlr2 toll like receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29959987 NCBI chrNW_004936576:522,234...531,660 JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:29959987 PMID:32068018 NCBI chrNW_004936727:1,936,066...1,937,766 JBrowse link
G Tp53 tumor protein p53 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30009776 PMID:34713381 NCBI chrNW_004936595:919,807...935,367 JBrowse link
Chemical and Drug Induced Liver Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aass aminoadipate-semialdehyde synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936605:3,135,977...3,190,956 JBrowse link
G Abcb1 ATP binding cassette subfamily B member 1 severity
susceptibility
ISO CTD Direct Evidence: marker/mechanism
DNA:SNP::2677G>T/A(rs2032582)(human)
CTD
RGD
PMID:20623750 PMID:26134275 PMID:27296832 RGD:11041130 RGD:14700895 NCBI chrNW_004936763:1,225,355...1,308,257 JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 severity ISO DNA:SNP: :rs2287616(human) RGD PMID:27293027 RGD:14402413 NCBI chrNW_004936469:10,521,576...10,599,005 JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18466103 NCBI chrNW_004936501:3,400,971...3,467,061 JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 susceptibility ISO DNA:polymorphism:promoter:-24C>T(human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:17241877 PMID:18381794 PMID:18466103 PMID:25196354 RGD:14700812 RGD:14700814 NCBI chrNW_004936636:292,631...341,999 JBrowse link
G Abi1 abl interactor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936484:2,090,605...2,194,109 JBrowse link
G Acox3 acyl-CoA oxidase 3, pristanoyl ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936477:19,696,274...19,731,338 JBrowse link
G Acsl1 acyl-CoA synthetase long chain family member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936554:4,425,518...4,484,853 JBrowse link
G Actb actin beta ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:liver
CTD
RGD
PMID:22563491 PMID:25231249 RGD:9587759 NCBI chrNW_004936765:667,107...670,627 JBrowse link
G Actn4 actinin alpha 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936801:1,333,077...1,402,885 JBrowse link
G Actr3 actin related protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936469:55,639,345...55,699,330 JBrowse link
G Ada adenosine deaminase ISO protein:increased expression:liver RGD PMID:21161045 RGD:5128859 NCBI chrNW_004936530:2,217,713...2,224,070 JBrowse link
G Adam8 ADAM metallopeptidase domain 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24646716 NCBI chrNW_004936486:19,389,925...19,403,577 JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO CTD Direct Evidence: therapeutic CTD PMID:20709802 NCBI chrNW_004936578:3,168,599...3,179,369 JBrowse link
G Adipor2 adiponectin receptor 2 severity ISO associated with obesity, LPS;mRNA:decreased expression:liver (rat) RGD PMID:23838384 RGD:8695926 NCBI chrNW_004936606:1,911,104...2,007,109 JBrowse link
G Agt angiotensinogen ISO CTD Direct Evidence: marker/mechanism CTD PMID:29499335 NCBI chrNW_004936484:19,713,299...19,721,144 JBrowse link
G Ahr aryl hydrocarbon receptor ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:21890736 PMID:34848246 NCBI chrNW_004936546:3,737,908...3,783,492 JBrowse link
G Aifm1 apoptosis inducing factor mitochondria associated 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25743375 NCBI chrNW_004936479:1,441,508...1,477,133 JBrowse link
G Ak4 adenylate kinase 4 ISO protein:increased expression:liver (rat) RGD PMID:16538043 RGD:2301096 NCBI chrNW_004936692:2,593,409...2,654,583 JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:29763686 PMID:32805337 RGD:27226688 NCBI chrNW_004936474:26,680,736...26,696,996 JBrowse link
G Aldh1l2 aldehyde dehydrogenase 1 family member L2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936492:9,605,611...9,657,717 JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member severity
susceptibility
ISO DNA:deletion:exon 3 (mouse)
protein:increased expression:liver
RGD PMID:21138988 PMID:24492981 PMID:30121625 RGD:14975148 RGD:15036810 RGD:7241599 NCBI chrNW_004936558:4,362,693...4,387,705 JBrowse link
G Aldh9a1 aldehyde dehydrogenase 9 family member A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936481:19,630,045...19,650,009 JBrowse link
G Aldob aldolase, fructose-bisphosphate B ISO CTD Direct Evidence: marker/mechanism CTD PMID:16115720 NCBI chrNW_004936524:9,584,302...9,592,961 JBrowse link
G Anxa2 annexin A2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004936471:21,274,112...21,329,286 JBrowse link
G Anxa6 annexin A6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936647:3,978,047...4,029,485 JBrowse link
G Apoa1 apolipoprotein A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chrNW_004936542:2,111,055...2,112,626 JBrowse link
G Apoe apolipoprotein E ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chrNW_004936706:1,512,438...1,516,805 JBrowse link
G Apoh apolipoprotein H ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:plasma:
CTD
RGD
PMID:16099942 PMID:23288050 RGD:10054107 NCBI chrNW_004936541:6,683,483...6,695,094 JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator ISO CTD Direct Evidence: marker/mechanism CTD PMID:20935161 NCBI chrNW_004936580:1,038,420...1,093,319 JBrowse link
G Atg5 autophagy related 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22491424 NCBI chrNW_004936564:2,759,085...2,885,394 JBrowse link
G Atoh8 atonal bHLH transcription factor 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004936712:1,529,508...1,552,148 JBrowse link
G Atp6v1d ATPase H+ transporting V1 subunit D ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513
G Bad BCL2 associated agonist of cell death treatment ISO RGD PMID:25447754 RGD:10053709 NCBI chrNW_004936599:4,924,349...4,933,683 JBrowse link
G Bax BCL2 associated X, apoptosis regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:17906064 NCBI chrNW_004936664:2,968,103...2,973,652 JBrowse link
G Bdh1 3-hydroxybutyrate dehydrogenase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004936833:367,790...409,966 JBrowse link
G Bdkrb2 bradykinin receptor B2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30685357 NCBI chrNW_004936604:548,844...551,031 JBrowse link
G Blvrb biliverdin reductase B ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936661:2,808,998...2,818,123 JBrowse link
G Bpnt1 3'(2'), 5'-bisphosphate nucleotidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936650:2,113,933...2,138,487 JBrowse link
G Brd4 bromodomain containing 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936596:5,176,682...5,246,102 JBrowse link
G C3 complement C3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chrNW_004936588:3,985,732...4,023,221 JBrowse link
G Ca3 carbonic anhydrase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 PMID:25231249 NCBI chrNW_004936544:337,437...347,760 JBrowse link
G Cabp1 calcium binding protein 1 ISO protein:increased expression:liver RGD PMID:21138988 RGD:7241599 NCBI chrNW_004936668:324,299...339,334 JBrowse link
G Cadps2 calcium dependent secretion activator 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chrNW_004936605:2,505,064...3,012,322 JBrowse link
G Canx calnexin ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936739:1,051,853...1,085,658 JBrowse link
G Cap1 cyclase associated actin cytoskeleton regulatory protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936474:21,854,454...21,881,622 JBrowse link
G Casp8 caspase 8 treatment ISO RGD PMID:25447754 RGD:10053709 NCBI chrNW_004936726:554,627...596,334 JBrowse link
G Cast calpastatin ISO RGD PMID:16871587 RGD:5683869 NCBI chrNW_004936523:6,688,153...6,798,184 JBrowse link
G Cat catalase ISO protein:decreased expression:liver
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:20623750 PMID:21138988 PMID:25231249 RGD:7241599 NCBI chrNW_004936533:3,601,270...3,637,128 JBrowse link
G Ccdc80 coiled-coil domain containing 80 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004936536:294,650...330,875 JBrowse link
G Cct3 chaperonin containing TCP1 subunit 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936580:5,537,338...5,554,384 JBrowse link
G Cct5 chaperonin containing TCP1 subunit 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936643:2,354,799...2,368,048 JBrowse link
G Cdc25b cell division cycle 25B ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004936485:14,897,050...14,914,034 JBrowse link
G Cds1 CDP-diacylglycerol synthase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004936738:160,346...227,687 JBrowse link
G Cela1 chymotrypsin like elastase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004936512:8,901,674...8,919,819 JBrowse link
G Cfap20 cilia and flagella associated protein 20 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936475:10,011,671...10,023,643 JBrowse link
G Chrm3 cholinergic receptor muscarinic 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20197374 NCBI chrNW_004936484:13,953,141...14,373,174 JBrowse link
G Ckb creatine kinase B ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936621:1,612,398...1,615,821 JBrowse link
G Clu clusterin ISO CTD Direct Evidence: marker/mechanism CTD PMID:20623750 NCBI chrNW_004936675:499,745...513,515 JBrowse link
G Col14a1 collagen type XIV alpha 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004936470:26,440,606...26,643,015 JBrowse link
G Col3a1 collagen type III alpha 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:16679477 NCBI chrNW_004936506:8,886,494...8,923,921 JBrowse link
G Comt catechol-O-methyltransferase ISO protein:decreased expression:liver RGD PMID:21138988 RGD:7241599 NCBI chrNW_004936619:3,847,059...3,883,866 JBrowse link
G Coq9 coenzyme Q9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936475:9,502,638...9,517,601 JBrowse link
G Cpb2 carboxypeptidase B2 ISO mRNA,protein:increased expression,increased activity:liver,plasma RGD PMID:19386599 RGD:7243112 NCBI chrNW_004936857:577,067...609,855 JBrowse link
G Cps1 carbamoyl-phosphate synthase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936586:5,739,038...5,850,317 JBrowse link
G Csf3 colony stimulating factor 3 ISO CTD Direct Evidence: therapeutic CTD PMID:20005281 NCBI chrNW_004936490:15,142,526...15,146,375 JBrowse link
G Ctnnb1 catenin beta 1 ISO CTD Direct Evidence: therapeutic CTD PMID:19679878 NCBI chrNW_004936473:29,999,542...30,034,610 JBrowse link
G Ctse cathepsin E ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004936557:6,485,783...6,498,805 JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 ISO CTD Direct Evidence: therapeutic CTD PMID:11739529 NCBI chrNW_004936676:60,869...63,028 JBrowse link
G Dbt dihydrolipoamide branched chain transacylase E2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936748:342,655...386,017 JBrowse link
G Ddb1 damage specific DNA binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936581:1,710,382...1,742,598 JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17984051 NCBI chrNW_004936498:4,514,212...4,544,523 JBrowse link
G Dhfr dihydrofolate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19648163 NCBI chrNW_004936469:67,962...83,116 JBrowse link
G Dlat dihydrolipoamide S-acetyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936612:2,395,452...2,437,592 JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chrNW_004936653:1,554,534...1,558,832 JBrowse link
G Dnajc12 DnaJ heat shock protein family (Hsp40) member C12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chrNW_004936521:10,360,775...10,403,201 JBrowse link
G Dsc2 desmocollin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004936682:2,057,331...2,091,034 JBrowse link
G E2f1 E2F transcription factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30515189 NCBI chrNW_004936561:6,894,827...6,901,058 JBrowse link
G Echdc1 ethylmalonyl-CoA decarboxylase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004936639:2,351,777...2,394,539 JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936486:19,488,619...19,496,583 JBrowse link
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004936577:4,486,617...4,516,379 JBrowse link
G Eif2ak1 eukaryotic translation initiation factor 2 alpha kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25411909 NCBI chrNW_004936750:389,913...430,783 JBrowse link
G Eif4ebp2 eukaryotic translation initiation factor 4E binding protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936521:8,182,740...8,207,466 JBrowse link
G Endog endonuclease G ISO protein:decreased expression:mitochondrion: RGD PMID:22509279 RGD:9685364 NCBI chrNW_004936487:16,282,115...16,285,486 JBrowse link
G Eng endoglin ISO protein:increased expression:liver (rat) RGD PMID:21146604 RGD:7257529 NCBI chrNW_004936487:15,467,165...15,499,180 JBrowse link
G Eno1 enolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 PMID:25231249 NCBI chrNW_004936623:3,115,357...3,130,289 JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 ISO protein:increased activity:serum: RGD PMID:17850827 RGD:9685426 NCBI chrNW_004936470:26,994,549...27,099,758 JBrowse link
G Ephx1 epoxide hydrolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004936526:2,589,254...2,652,831 JBrowse link
G Erlec1 endoplasmic reticulum lectin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chrNW_004936491:351,813...377,978 JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30538632 NCBI chrNW_004936541:4,613,197...4,705,911 JBrowse link
G F13a1 coagulation factor XIII A chain ISO RGD PMID:22019897 RGD:11041813 NCBI chrNW_004936534:6,199,066...6,360,374 JBrowse link
G F3 coagulation factor III, tissue factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:22407844 NCBI chrNW_004936537:4,637,028...4,647,915 JBrowse link
G Fadd Fas associated via death domain treatment ISO RGD PMID:25447754 PMID:26062544 RGD:10053709 RGD:11341803 NCBI chrNW_004936599:633,501...639,412 JBrowse link
G Fads1 fatty acid desaturase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004936581:1,312,199...1,327,046 JBrowse link
G Fads2 fatty acid desaturase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004936581:1,203,410...1,233,330 JBrowse link
G Fas Fas cell surface death receptor ISO protein:increased expression:liver (rat) RGD PMID:16831245 RGD:8662853 NCBI chrNW_004936735:209,369...234,582 JBrowse link
G Fasn fatty acid synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004936594:5,591,785...5,609,886 JBrowse link
G Fcmr Fc fragment of IgM receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004936557:5,707,138...5,718,192 JBrowse link
G Fga fibrinogen alpha chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:20974703 NCBI chrNW_004936576:1,322,406...1,329,743 JBrowse link
G Fgf21 fibroblast growth factor 21 severity ISO mRNA:increased expression:liver (rat) RGD PMID:29883717 RGD:15045603 NCBI chrNW_004936664:2,826,823...2,828,330 JBrowse link
G Flt1 fms related receptor tyrosine kinase 1 ISO CTD Direct Evidence: therapeutic CTD PMID:21135413 NCBI chrNW_004936472:23,442,946...23,617,523 JBrowse link
G Ftl ferritin light chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936664:2,976,325...2,977,878 JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 ISO mRNA:decreased expression:liver (mouse) RGD PMID:28189721 RGD:14695531 NCBI chrNW_004936490:17,605,865...17,614,754 JBrowse link
G G6pd glucose-6-phosphate dehydrogenase treatment ISO RGD PMID:21864513 RGD:10449168 NCBI chrNW_004936809:1,269,900...1,285,853 JBrowse link
G Gadd45a growth arrest and DNA damage inducible alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:20623750 NCBI chrNW_004936591:3,998,359...4,001,491 JBrowse link
G Ganab glucosidase II alpha subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936581:613,292...633,075 JBrowse link
G Gc GC vitamin D binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chrNW_004936598:3,220,029...3,256,091 JBrowse link
G Gclc glutamate-cysteine ligase catalytic subunit ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:17573345 PMID:19481141 RGD:10402383 NCBI chrNW_004936476:7,371,270...7,418,756 JBrowse link
G Gda guanine deaminase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936503:8,191,925...8,279,806 JBrowse link
G Gdi1 GDP dissociation inhibitor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936809:1,188,793...1,194,816 JBrowse link
G Gfer growth factor, augmenter of liver regeneration treatment ISO RGD PMID:15968720 PMID:22033404 RGD:9685722 RGD:9685727 NCBI chrNW_004936694:2,051,362...2,053,812 JBrowse link
G Ggh gamma-glutamyl hydrolase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21219404 NCBI chrNW_004936496:10,485,528...10,505,506 JBrowse link
G Ggt1 gamma-glutamyltransferase 1 ISO RGD PMID:10934156 RGD:14701049 NCBI chrNW_004936619:762,278...791,610 JBrowse link
G Glud1 glutamate dehydrogenase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:33483742 NCBI chrNW_004936601:5,415,857...5,435,964 JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004936636:617,376...640,424 JBrowse link
G Gpd1 glycerol-3-phosphate dehydrogenase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936512:7,762,325...7,770,007 JBrowse link
G Gpt glutamic--pyruvic transaminase treatment ISO CTD Direct Evidence: marker/mechanism
protein:increased expression, activity:serum:
CTD
RGD
PMID:145039 PMID:19085960 PMID:19481104 PMID:21772750 PMID:27293452 More... RGD:14975162 RGD:14975166 RGD:14975168 RGD:14975249 NCBI chrNW_004936470:7,765,810...7,770,837 JBrowse link
G Gpt2 glutamic--pyruvic transaminase 2 ISO protein:increased expression, activity:serum: RGD PMID:19085960 RGD:14975249 NCBI chrNW_004936475:262,558...299,766 JBrowse link
G Gsn gelsolin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chrNW_004936487:9,749,755...9,802,787 JBrowse link
G Gsr glutathione-disulfide reductase treatment ISO CTD Direct Evidence: marker/mechanism
mRNA, protein:increased expression:liver
RGD
CTD
PMID:23554813 PMID:24154663 PMID:25226513 PMID:28069987 RGD:10401878 RGD:7257532 NCBI chrNW_004936792:531,076...579,083 JBrowse link
G Gstm3 glutathione S-transferase mu 3 ISO CTD Direct Evidence: therapeutic CTD PMID:25743375 NCBI chrNW_004936704:1,233,909...1,236,864 JBrowse link
G Gsto1 glutathione S-transferase omega 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936600:1,932,152...1,943,342 JBrowse link
G Gstp1 glutathione S-transferase pi 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20623750 PMID:25226513 NCBI chrNW_004936599:2,197,681...2,200,642 JBrowse link
G Hacl1 2-hydroxyacyl-CoA lyase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chrNW_004936473:2,823,183...2,856,077 JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004936493:6,182,786...6,224,601 JBrowse link
G Hao2 hydroxyacid oxidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004936627:4,167,501...4,179,596 JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20623750 NCBI chrNW_004936515:6,030,402...6,051,161 JBrowse link
G Hmgb1 high mobility group box 1 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:19783637 PMID:29091898 RGD:15090820 NCBI chrNW_004936472:25,236,728...25,246,585 JBrowse link
G Hmox1 heme oxygenase 1 treatment ISO CTD Direct Evidence: marker/mechanism|therapeutic RGD
CTD
PMID:18227147 PMID:22688006 PMID:22886620 PMID:29091898 RGD:10762620 RGD:15090820 NCBI chrNW_004936492:5,042,353...5,049,216 JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936691:650,753...694,362 JBrowse link
G Hpx hemopexin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chrNW_004936842:485,515...495,684 JBrowse link
G Hrh2 histamine receptor H2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22926047 NCBI chrNW_004936609:624,446...664,049 JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936487:13,348,465...13,352,717 JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 ISO protein:altered localization:liver (rat) RGD PMID:12376827 RGD:10059389 NCBI chrNW_004936542:7,577,192...7,581,598 JBrowse link
G Icam1 intercellular adhesion molecule 1 treatment ISO RGD PMID:29091898 RGD:15090820 NCBI chrNW_004936659:616,570...627,172 JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 severity ISO RGD PMID:31121248 RGD:14985250 NCBI chrNW_004936483:15,845,777...15,864,341 JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:32289347 NCBI chrNW_004936843:595,237...649,390 JBrowse link
G Ifng interferon gamma ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:12153990 PMID:21245496 PMID:30013034 RGD:14975100 NCBI chrNW_004936545:6,139,130...6,144,543 JBrowse link
G Igf1 insulin like growth factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23639586 PMID:25226513 NCBI chrNW_004936492:11,709,623...11,784,028 JBrowse link
G Il11 interleukin 11 ISO CTD Direct Evidence: therapeutic CTD PMID:11421492 NCBI chrNW_004936886:617,531...620,661 JBrowse link
G Il17a interleukin 17A ISO CTD Direct Evidence: marker/mechanism CTD PMID:19633216 PMID:24949944 NCBI chrNW_004936476:8,621,860...8,625,008 JBrowse link
G Il18 interleukin 18 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19164858 NCBI chrNW_004936612:2,306,963...2,325,086 JBrowse link
G Il1a interleukin 1 alpha ISO CTD Direct Evidence: therapeutic CTD PMID:8218930 NCBI chrNW_004936783:1,210,715...1,218,315 JBrowse link
G Il1b interleukin 1 beta treatment ISO CTD Direct Evidence: marker/mechanism|therapeutic RGD
CTD
PMID:19164858 PMID:23102243 PMID:28138970 PMID:29091898 PMID:29278859 More... RGD:13793380 RGD:14975281 RGD:15036799 RGD:15090820 RGD:7204421 NCBI chrNW_004936783:1,251,678...1,256,807 JBrowse link
G Il1r2 interleukin 1 receptor type 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17984051 NCBI chrNW_004936713:679,680...716,801 JBrowse link
G Il22 interleukin 22 ISO CTD Direct Evidence: therapeutic CTD PMID:15122762 PMID:16212920 PMID:23375450 NCBI chrNW_004936545:6,227,118...6,231,745 JBrowse link
G Il6 interleukin 6 treatment ISO CTD Direct Evidence: therapeutic RGD
CTD
PMID:7532385 PMID:15763341 PMID:29091898 RGD:15090820 NCBI chrNW_004936549:7,015,595...7,016,246 JBrowse link
G Immt inner membrane mitochondrial protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936712:1,257,427...1,301,045 JBrowse link
G Irak1 interleukin 1 receptor associated kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936809:891,407...900,311 JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor type 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004936577:3,896,455...4,198,396 JBrowse link
G Keap1 kelch like ECH associated protein 1 ISO RGD PMID:18417483 RGD:6893370 NCBI chrNW_004936659:785,059...793,775 JBrowse link
G Kitlg KIT ligand ISO CTD Direct Evidence: therapeutic CTD PMID:12594235 NCBI chrNW_004936507:5,566,144...5,650,412 JBrowse link
G Kng1 kininogen 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20362651 PMID:30685357 NCBI chrNW_004936578:3,255,335...3,281,296 JBrowse link
G Krt18 keratin 18 ISO mRNA, protein:increased expression:liver (mouse)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:17340120 PMID:19783637 PMID:33483742 RGD:18337498 NCBI chrNW_004936512:10,290,706...10,294,647 JBrowse link
G Krt8 keratin 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936512:10,247,049...10,254,748 JBrowse link
G Lap3 leucine aminopeptidase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936477:10,596,610...10,627,149 JBrowse link
G Lcn2 lipocalin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20362651 PMID:20623750 NCBI chrNW_004936487:15,721,752...15,725,396 JBrowse link
G Lgals3 galectin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22461450 NCBI chrNW_004936697:20,861...38,568 JBrowse link
G LOC101956757 neuronal regeneration related protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004936531:6,077,691...6,105,517 JBrowse link
G LOC101958062 glutathione S-transferase A4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936476:7,873,218...7,888,301 JBrowse link
G LOC101958900 glutathione S-transferase Mu 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004936704:1,142,990...1,150,491 JBrowse link
G LOC101958966 lipopolysaccharide binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004936561:3,017,471...3,035,481 JBrowse link
G LOC101959495 PZP alpha-2-macroglobulin like ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chrNW_004936870:497,071...542,364 JBrowse link
G LOC101960095 antileukoproteinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:17984051 NCBI chrNW_004936514:7,618,382...7,620,790 JBrowse link
G LOC101961588 cytochrome P450 2D17 ISO DNA:hypermethylation:promoter RGD PMID:27490558 RGD:14700879 NCBI chrNW_004936718:153,340...157,966 JBrowse link
G LOC101961662 biotinidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:15469856 NCBI chrNW_004936473:2,787,386...2,823,014 JBrowse link
G LOC101962856 ceruloplasmin ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004936519:6,431,156...6,473,183 JBrowse link
G LOC101966596 dehydrogenase/reductase SDR family member 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004936495:4,341,261...4,358,279 JBrowse link
G LOC101966907 histone H2AX treatment ISO RGD PMID:23265463 RGD:8693741 NCBI chrNW_004936542:4,046,930...4,049,017 JBrowse link
G LOC101968921 angiotensin-converting enzyme ISO mRNA:increased expression:liver (rat) RGD PMID:25143335 RGD:25671447 NCBI chrNW_004936541:4,157,847...4,178,156 JBrowse link
G LOC101969148 cytochrome P450 1A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:33814510 NCBI chrNW_004936471:33,682,730...33,688,332 JBrowse link
G LOC101969421 cytochrome P450 1A2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28762043 NCBI chrNW_004936471:33,704,616...33,709,455 JBrowse link
G LOC101969640 C-reactive protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936740:885,855...888,854 JBrowse link
G LOC101970101 cytochrome P450 1B1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:33814510 NCBI chrNW_004936663:345,021...355,188 JBrowse link
G LOC101970144 purine nucleoside phosphorylase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chrNW_004936877:686,539...692,832 JBrowse link
G LOC101970597 sulfotransferase 1C1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004936729:1,783,124...1,796,723 JBrowse link
G LOC101970831 serotransferrin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chrNW_004936529:6,917,762...6,947,512 JBrowse link
G LOC101972117 hepcidin antimicrobial peptide ISO mRNA:increased expression:hepatocyte RGD PMID:24373749 RGD:11041724 NCBI chrNW_004936570:1,009,344...1,010,654 JBrowse link
G LOC101972766 tubulin alpha-1A chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936512:6,959,656...6,964,299 JBrowse link
G LOC101973017 corticosteroid-binding globulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004936733:2,141,484...2,148,129 JBrowse link
G LOC101973029 cytochrome P450 2E1 treatment ISO DNA:hypermethylation:promoter
CTD Direct Evidence: marker/mechanism
associated with Endotoxemia
RGD
CTD
PMID:12668988 PMID:16770646 PMID:21741958 PMID:25681370 PMID:27324775 More... RGD:14700872 RGD:14700873 RGD:14700878 RGD:14700879 RGD:14700901 NCBI chrNW_004936486:19,691,822...19,702,684 JBrowse link
G LOC101976131 alpha-1-microglobulin/bikunin precursor ISO CTD Direct Evidence: marker/mechanism CTD PMID:18779383 NCBI chrNW_004936487:3,399,792...3,412,088 JBrowse link
G LOC101977223 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25448281 NCBI chrNW_004936695:2,263,868...2,265,373 JBrowse link
G LOC101977655 glutamate--cysteine ligase regulatory subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936537:5,356,914...5,378,998 JBrowse link
G LOC101978323 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial ISO mRNA, protein:decreased expression:kidney (mouse) RGD PMID:26476181 RGD:25671412 NCBI chrNW_004936646:1,899,686...1,904,104 JBrowse link
G Lpl lipoprotein lipase treatment ISO RGD PMID:27071702 RGD:13794380 NCBI chrNW_004936555:4,084,099...4,108,219 JBrowse link
G Lrat lecithin retinol acyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004936576:1,491,480...1,498,568 JBrowse link
G Ltb4r leukotriene B4 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:28487374 NCBI chrNW_004936722:232,320...233,802 JBrowse link
G Ltf lactotransferrin ISO CTD Direct Evidence: therapeutic CTD PMID:16141546 NCBI chrNW_004936596:344,287...373,788 JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18700144 NCBI chrNW_004936560:3,988,696...4,197,953 JBrowse link
G Mat1a methionine adenosyltransferase 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936716:126,628...142,986 JBrowse link
G Mccc1 methylcrotonyl-CoA carboxylase subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936566:409,558...468,898 JBrowse link
G Mdh1 malate dehydrogenase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chrNW_004936491:8,570,472...8,586,914 JBrowse link
G Me1 malic enzyme 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936510:7,425,983...7,571,090 JBrowse link
G Med1 mediator complex subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16109766 NCBI chrNW_004936490:14,625,201...14,663,184 JBrowse link
G Mmp2 matrix metallopeptidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15763341 NCBI chrNW_004936475:7,801,356...7,825,831 JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22507835 NCBI chrNW_004936514:7,038,240...7,045,873 JBrowse link
G Mst1 macrophage stimulating 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936529:1,298,853...1,306,088 JBrowse link
G Mst1r macrophage stimulating 1 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:22575169 NCBI chrNW_004936529:1,494,748...1,509,925 JBrowse link
G Mthfr methylenetetrahydrofolate reductase treatment ISO associated with precursor lymphoblastic lymphoma/leukemia; DNA:SNP: :677C>T(human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:18551038 PMID:19648163 PMID:30545275 RGD:14696733 NCBI chrNW_004936474:623,438...637,849 JBrowse link
G Mtpn myotrophin ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936592:644,618...679,615 JBrowse link
G Myd88 MYD88 innate immune signal transduction adaptor ameliorates ISO RGD PMID:17615358 RGD:150521532 NCBI chrNW_004936473:27,672,237...27,676,339 JBrowse link
G Ndufs3 NADH:ubiquinone oxidoreductase core subunit S3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936562:1,667,780...1,674,670 JBrowse link
G Nfatc4 nuclear factor of activated T cells 4 ISO CTD Direct Evidence: therapeutic CTD PMID:34192554 NCBI chrNW_004936722:178,866...187,847 JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 treatment ISO CTD Direct Evidence: therapeutic
induced by methotrexate (CHEBI:44185), treated by ferulic acid (CHEBI:17620)
RGD
CTD
PMID:18417483 PMID:22491424 PMID:22627062 PMID:24813929 PMID:26958860 More... RGD:15090820 RGD:21201280 RGD:21201283 RGD:21201305 RGD:21201308 RGD:6893370 NCBI chrNW_004936509:6,589,967...6,621,171 JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 treatment
susceptibility
ISO associated with tuberculosis ;DNA:SNPs,haplotypes: 3'utr,5'utr: (rs78872571,rs4647992) (human) RGD PMID:29091898 PMID:31490979 RGD:15090820 RGD:40902984 NCBI chrNW_004936520:733,760...850,563 JBrowse link
G Nfxl1 nuclear transcription factor, X-box binding like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chrNW_004936482:14,008,825...14,062,654 JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936490:10,634,788...10,640,182 JBrowse link
G Notch1 notch receptor 1 ISO CTD Direct Evidence: therapeutic CTD PMID:30394310 NCBI chrNW_004936669:1,292,016...1,334,061 JBrowse link
G Nox4 NADPH oxidase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004936736:230,465...394,859 JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 treatment ISO RGD PMID:28472605 PMID:28522909 PMID:29091898 RGD:13439737 RGD:13439739 RGD:15090820 NCBI chrNW_004936475:19,771,384...19,785,034 JBrowse link
G Nr0b2 nuclear receptor subfamily 0 group B member 2 ISO CTD Direct Evidence: therapeutic CTD PMID:29943110 NCBI chrNW_004936474:11,316,857...11,319,669 JBrowse link
G Nr1d1 nuclear receptor subfamily 1 group D member 1 treatment ISO RGD PMID:24497272 RGD:10448995 NCBI chrNW_004936490:15,206,194...15,213,858 JBrowse link
G Nr1h3 nuclear receptor subfamily 1 group H member 3 ISO CTD Direct Evidence: therapeutic CTD PMID:17256725 NCBI chrNW_004936562:1,937,665...1,946,680 JBrowse link
G Nr1h4 nuclear receptor subfamily 1 group H member 4 severity
treatment
ISO mRNA:decreased expression:liver (rat)
CTD Direct Evidence: marker/mechanism
protein:decreased expression:liver (rat)
RGD
CTD
PMID:12875239 PMID:20573685 PMID:22711662 PMID:28827769 PMID:29091898 More... RGD:14701035 RGD:14701036 RGD:15042870 RGD:15045609 RGD:15090820 NCBI chrNW_004936492:13,315,265...13,365,186 JBrowse link
G Nr1i2 nuclear receptor subfamily 1 group I member 2 susceptibility ISO CTD Direct Evidence: marker/mechanism|therapeutic
associated with tuberculosis ;DNA:SNP,haplotypes:promoter: (rs3814055) (human)
CTD
RGD
PMID:19797606 PMID:28058446 PMID:31490979 RGD:40902984 NCBI chrNW_004936536:6,691,590...6,726,421 JBrowse link
G Nr1i3 nuclear receptor subfamily 1 group I member 3 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:14742670 PMID:25656644 PMID:28058446 NCBI chrNW_004936903:527,838...533,930 JBrowse link
G Nr2f2 nuclear receptor subfamily 2 group F member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936483:6,886,447...6,900,986 JBrowse link
G Nr5a2 nuclear receptor subfamily 5 group A member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29515023 NCBI chrNW_004936567:4,084,161...4,194,858 JBrowse link
G Nus1 NUS1 dehydrodolichyl diphosphate synthase subunit ISO CTD Direct Evidence: therapeutic CTD PMID:33812996 NCBI chrNW_004936658:695,431...718,891 JBrowse link
G Ociad1 OCIA domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936482:14,780,284...14,805,718 JBrowse link
G Ogdh oxoglutarate dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936478:19,506,845...19,584,411 JBrowse link
G P4hb prolyl 4-hydroxylase subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936594:5,368,199...5,379,215 JBrowse link
G Pah phenylalanine hydroxylase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936492:11,342,566...11,412,323 JBrowse link
G Pan2 poly(A) specific ribonuclease subunit PAN2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chrNW_004936646:719,821...737,284 JBrowse link
G Panx1 pannexin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29246445 NCBI chrNW_004936674:736,911...773,406 JBrowse link
G Park7 Parkinsonism associated deglycase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936623:2,422,780...2,436,817 JBrowse link
G Pc pyruvate carboxylase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936599:2,677,770...2,793,033 JBrowse link
G Pcolce procollagen C-endopeptidase enhancer ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004936543:653,844...659,905 JBrowse link
G Pcyt1a phosphate cytidylyltransferase 1A, choline ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004936784:884,751...938,901 JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:21182459 PMID:31809757 NCBI chrNW_004936585:4,701,012...4,713,421 JBrowse link
G Pdlim5 PDZ and LIM domain 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936687:1,944,095...2,152,501 JBrowse link
G Pex11a peroxisomal biogenesis factor 11 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004936483:15,474,484...15,480,527 JBrowse link
G Pgm1 phosphoglucomutase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936692:1,160,836...1,221,270 JBrowse link
G Plat plasminogen activator, tissue type ISO CTD Direct Evidence: marker/mechanism CTD PMID:22507835 NCBI chrNW_004936785:476,200...503,371 JBrowse link
G Plg plasminogen ISO CTD Direct Evidence: marker/mechanism CTD PMID:22507835 NCBI chrNW_004936489:11,775,243...11,808,482 JBrowse link
G Pls3 plastin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936499:246,042...335,440 JBrowse link
G Pnrc1 proline rich nuclear receptor coactivator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936510:3,109,114...3,112,616 JBrowse link
G Polg DNA polymerase gamma, catalytic subunit no_association
susceptibility
ISO DNA:missense mutations:cds:p.Q1236H, p.E1143G (33708G>T, 3428A>G) (human)
CTD Direct Evidence: marker/mechanism
DNA:missense mutation:cds:p.W748S, p.E1143G (2243G>C, 3428A>G) (human)
RGD
CTD
PMID:18208989 PMID:20138553 PMID:25065347 PMID:30255931 RGD:15039297 RGD:15039302 NCBI chrNW_004936483:15,178,947...15,196,277 JBrowse link
G Polr2g RNA polymerase II subunit G ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936581:523,018...528,167 JBrowse link
G Pon1 paraoxonase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chrNW_004936585:4,954,871...4,979,560 JBrowse link
G Ppara peroxisome proliferator activated receptor alpha ISO LPS-induced acute liver damage
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:21262334 PMID:24385052 RGD:5509941 NCBI chrNW_004936629:3,672,445...3,725,645 JBrowse link
G Pparg peroxisome proliferator activated receptor gamma ISO mRNA, protein:decreased expression:liver RGD PMID:26599535 RGD:11554658 NCBI chrNW_004936602:1,230,907...1,368,588 JBrowse link
G Pptc7 protein phosphatase targeting COQ7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004936558:3,491,225...3,531,886 JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 treatment ISO RGD PMID:29091898 RGD:15090820 NCBI chrNW_004936518:1,817,051...1,843,376 JBrowse link
G Prkcd protein kinase C delta ISO CTD Direct Evidence: therapeutic CTD PMID:30393195 NCBI chrNW_004936473:3,892,625...3,923,467 JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:21224054 NCBI chrNW_004936590:4,722,914...4,887,615 JBrowse link
G Ptf1a pancreas associated transcription factor 1a ISO CTD Direct Evidence: therapeutic CTD PMID:21182459 NCBI chrNW_004936520:4,978,896...4,980,648 JBrowse link
G Ptges2 prostaglandin E synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31444509 NCBI chrNW_004936487:15,703,179...15,708,408 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 treatment ISO CTD Direct Evidence: therapeutic CTD
RGD
PMID:11743745 PMID:29091898 RGD:15090820 NCBI chrNW_004936481:3,821,564...3,828,086 JBrowse link
G Pum1 pumilio RNA binding family member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936474:14,243,325...14,363,461 JBrowse link
G Pygl glycogen phosphorylase L ISO protein:increased expression:serum (rat)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:25231249 PMID:25336395 RGD:21079733 NCBI chrNW_004936495:14,692,688...14,728,663 JBrowse link
G Rasa1 RAS p21 protein activator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936469:5,839,560...5,933,049 JBrowse link
G Rbp1 retinol binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chrNW_004936540:1,600,673...1,626,573 JBrowse link
G Rdh13 retinol dehydrogenase 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27865848 NCBI chrNW_004936886:356,068...368,525 JBrowse link
G Reep5 receptor accessory protein 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chrNW_004936531:7,055,841...7,103,810 JBrowse link
G Rgn regucalcin ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004936502:12,872,938...12,891,270 JBrowse link
G Ripk3 receptor interacting serine/threonine kinase 3 ISO CTD Direct Evidence: therapeutic
protein:increased expression:liver (mouse)
CTD
RGD
PMID:26769846 PMID:28205631 RGD:127229945 NCBI chrNW_004936722:209,019...212,817 JBrowse link
G Selenbp1 selenium binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20623750 NCBI chrNW_004936580:1,573,208...1,584,266 JBrowse link
G Sema4a semaphorin 4A ISO CTD Direct Evidence: marker/mechanism CTD PMID:33290778 NCBI chrNW_004936580:5,404,380...5,431,183 JBrowse link
G Senp2 SUMO specific peptidase 2 ISO CTD Direct Evidence: therapeutic CTD PMID:29535048 NCBI chrNW_004936578:4,252,718...4,290,452 JBrowse link
G Serpine1 serpin family E member 1 treatment ISO associated with precursor lymphoblastic lymphoma/leukemia;DNA:SNPs: :DNA:SNPs: :677C>T, 1298A>C(human) RGD PMID:23183238 RGD:14696750 NCBI chrNW_004936543:1,032,543...1,040,956 JBrowse link
G Serping1 serpin family G member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004936581:4,911,403...4,924,484 JBrowse link
G Sesn2 sestrin 2 ISO CTD Direct Evidence: therapeutic CTD PMID:28209544 NCBI chrNW_004936474:12,416,652...12,436,799 JBrowse link
G Sgf29 SAGA complex associated factor 29 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004936501:12,008,601...12,024,113 JBrowse link
G Shc1 SHC adaptor protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 PMID:32659284 NCBI chrNW_004936580:4,511,560...4,522,003 JBrowse link
G Slc10a1 solute carrier family 10 member 1 ISO mRNA:decreased expression:liver (rat) RGD PMID:28827769 RGD:15045609 NCBI chrNW_004936495:12,958,983...12,975,755 JBrowse link
G Slc10a7 solute carrier family 10 member 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chrNW_004936535:2,792,576...3,038,504 JBrowse link
G Slc13a4 solute carrier family 13 member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004936592:450,237...497,050 JBrowse link
G Slc22a8 solute carrier family 22 member 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004936581:319,372...343,171 JBrowse link
G Slc25a29 solute carrier family 25 member 29 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004936604:3,950,266...3,965,836 JBrowse link
G Slc7a5 solute carrier family 7 member 5 treatment ISO RGD PMID:9200186 RGD:151357001 NCBI chrNW_004936641:1,513,110...1,538,955 JBrowse link
G Snx18 sorting nexin 18 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17984051 NCBI chrNW_004936480:13,108,510...13,137,550 JBrowse link
G Sod1 superoxide dismutase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20623750 PMID:27349771 NCBI chrNW_004936500:10,345,154...10,352,873 JBrowse link
G Sod2 superoxide dismutase 2 severity
treatment
susceptibility
ISO associated with acute lymphoblastic leukemia;DNA:SNP: :(rs4880)(human)
DNA:SNP:cds:p.Val16Ala(human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:19332662 PMID:19647030 PMID:20578157 PMID:25226513 PMID:27019981 RGD:11060605 RGD:26923957 RGD:26923959 RGD:26923961 NCBI chrNW_004936489:11,178,338...11,191,601 JBrowse link
G Sord sorbitol dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:12763371 NCBI chrNW_004936471:7,760,097...7,805,475 JBrowse link
G Sorl1 sortilin related receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chrNW_004936542:6,192,407...6,352,835 JBrowse link
G Spp1 secreted phosphoprotein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20623750 NCBI chrNW_004936905:148,956...156,023 JBrowse link
G Srp72 signal recognition particle 72 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chrNW_004936482:18,687,088...18,721,734 JBrowse link
G Stat4 signal transducer and activator of transcription 4 severity ISO protein:increased phosphorylation:liver, inflammatory cell (mouse)
mRNA:increased expression:liver, macrophage (mouse)
RGD PMID:23876342 PMID:24731448 RGD:25671417 RGD:25671422 NCBI chrNW_004936506:7,091,982...7,185,938 JBrowse link
G Sult2b1 sulfotransferase family 2B member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27052460 NCBI chrNW_004936664:2,626,810...2,655,290 JBrowse link
G Suox sulfite oxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936646:411,543...415,709 JBrowse link
G Tagln2 transgelin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004936740:689,745...697,145 JBrowse link
G Taldo1 transaldolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19436114 NCBI chrNW_004936888:531,002...540,194 JBrowse link
G Tbxa2r thromboxane A2 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:22206755 NCBI chrNW_004936588:2,040,712...2,044,635 JBrowse link
G Tctn1 tectonic family member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17984051 NCBI chrNW_004936558:3,552,909...3,581,212 JBrowse link
G Tgfb1 transforming growth factor beta 1 treatment ISO RGD PMID:27516150 RGD:14995464 NCBI chrNW_004936661:3,742,080...3,758,266 JBrowse link
G Tgfbr1 transforming growth factor beta receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28560358 NCBI chrNW_004936524:7,656,523...7,680,043 JBrowse link
G Thpo thrombopoietin ISO CTD Direct Evidence: therapeutic CTD PMID:33122006 NCBI chrNW_004936578:5,508,669...5,515,984 JBrowse link
G Tlr4 toll like receptor 4 disease_progression ISO RGD PMID:17504260 RGD:14697733 NCBI chrNW_004936487:6,519,140...6,532,018 JBrowse link
G Tlr5 toll like receptor 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30508503 NCBI chrNW_004936526:383,490...387,007 JBrowse link
G Tmed7 transmembrane p24 trafficking protein 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chrNW_004936742:779,964...791,738 JBrowse link
G Tmem117 transmembrane protein 117 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chrNW_004936512:2,327,765...2,765,488 JBrowse link
G Tmem164 transmembrane protein 164 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004936499:5,042,638...5,199,433 JBrowse link
G Tmem38b transmembrane protein 38B ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004936559:6,501,890...6,553,446 JBrowse link
G Tnf tumor necrosis factor treatment
severity
ISO protein:increased expression:serum (rat)
CTD Direct Evidence: marker/mechanism|therapeutic
RGD
CTD
PMID:7532385 PMID:9309314 PMID:9696492 PMID:10801287 PMID:10801288 More... RGD:10450531 RGD:14696804 RGD:14975281 RGD:14995429 RGD:14995432 RGD:14995435 RGD:14995437 RGD:14995485 RGD:15036799 RGD:15090820 NCBI chrNW_004936727:1,936,066...1,937,766 JBrowse link
G Trpm2 transient receptor potential cation channel subfamily M member 2 ISO RGD PMID:24569808 RGD:9999438 NCBI chrNW_004936500:21,960...76,895 JBrowse link
G Ttr transthyretin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chrNW_004936682:1,628,489...1,635,495 JBrowse link
G Tubb4b tubulin beta 4B class IVb ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936669:749,203...751,622 JBrowse link
G Uba5 ubiquitin like modifier activating enzyme 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chrNW_004936529:5,997,459...6,010,776 JBrowse link
G Unc93b1 unc-93 homolog B1, TLR signaling regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004936599:2,109,292...2,146,006 JBrowse link
G Usp5 ubiquitin specific peptidase 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936709:952,225...966,429 JBrowse link
G Vegfa vascular endothelial growth factor A treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:17784864 PMID:25231249 RGD:15003197 NCBI chrNW_004936476:16,245,134...16,261,180 JBrowse link
G Vim vimentin ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004936520:10,051,692...10,059,324 JBrowse link
G Vwf von Willebrand factor ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:liver:
CTD
RGD
PMID:7531171 PMID:28527913 RGD:11079232 NCBI chrNW_004936709:1,578,137...1,741,877 JBrowse link
G Wasl WASP like actin nucleation promoting factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004936605:1,741,832...1,816,694 JBrowse link
G Xrcc1 X-ray repair cross complementing 1 susceptibility ISO DNA:haploinsufficiency: : (mouse) RGD PMID:21737425 RGD:15036796 NCBI chrNW_004936706:752,571...783,746 JBrowse link
G Xylb xylulokinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chrNW_004936473:27,725,955...27,767,319 JBrowse link
G Zdhhc23 zinc finger DHHC-type palmitoyltransferase 23 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chrNW_004936536:1,434,774...1,450,872 JBrowse link
drug allergy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20216337 NCBI chrNW_004936636:292,631...341,999 JBrowse link
G Adora1 adenosine A1 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19019667 NCBI chrNW_004936567:1,430,128...1,508,626 JBrowse link
G Adora2a adenosine A2a receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19019667 NCBI chrNW_004936619:597,970...618,564 JBrowse link
G Ccl24 C-C motif chemokine ligand 24 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14616128 NCBI chrNW_004936543:2,400,743...2,403,558 JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16630147 NCBI chrNW_004936547:479,261...504,757 JBrowse link
G Cysltr2 cysteinyl leukotriene receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15970796 NCBI chrNW_004936565:1,917,970...1,919,027 JBrowse link
G Faslg Fas ligand ISO CTD Direct Evidence: marker/mechanism CTD PMID:19706026 NCBI chrNW_004936481:14,789,547...14,795,780 JBrowse link
G Fcer1a Fc fragment of IgE receptor Ia ISO CTD Direct Evidence: marker/mechanism CTD PMID:17125826 PMID:20485159 NCBI chrNW_004936740:1,201,370...1,206,871 JBrowse link
G Fcer1g Fc fragment of IgE receptor Ig ISO CTD Direct Evidence: marker/mechanism CTD PMID:18534082 PMID:18595682 NCBI chrNW_004936903:514,278...517,975 JBrowse link
G Gstp1 glutathione S-transferase pi 1 susceptibility ISO CTD Direct Evidence: marker/mechanism
associated with Acquired Immunodeficiency Syndrome;DNA:polymorphism:exon:A>G313 (rs1695) (human)
CTD
RGD
PMID:16297214 PMID:20485159 RGD:5490995 NCBI chrNW_004936599:2,197,681...2,200,642 JBrowse link
G Hnmt histamine N-methyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:20485159 NCBI chrNW_004936469:38,125,877...38,166,429 JBrowse link
G Il10 interleukin 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19222424 PMID:20485159 NCBI chrNW_004936557:5,834,874...5,838,502 JBrowse link
G Il13 interleukin 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20485159 NCBI chrNW_004936647:2,529,933...2,532,503 JBrowse link
G Il2 interleukin 2 ISO RGD PMID:1549655 RGD:8662975 NCBI chrNW_004936662:1,594,953...1,599,625 JBrowse link
G Il4r interleukin 4 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:20485159 NCBI chrNW_004936501:11,025,590...11,058,807 JBrowse link
G LOC101956126 heat shock 70 kDa protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16538175 NCBI chrNW_004936727:1,732,323...1,735,128 JBrowse link
G LOC101956412 heat shock 70 kDa protein 1-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:16538175 NCBI chrNW_004936727:1,735,880...1,745,231 JBrowse link
G LOC101968920 eotaxin ISO CTD Direct Evidence: marker/mechanism CTD PMID:14616128 NCBI chrNW_004936538:835,436...848,907 JBrowse link
G LOC101968921 angiotensin-converting enzyme ISO CTD Direct Evidence: marker/mechanism CTD PMID:18727619 NCBI chrNW_004936541:4,157,847...4,178,156 JBrowse link
G Ltc4s leukotriene C4 synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16433794 NCBI chrNW_004936739:975,494...978,426 JBrowse link
G Mln motilin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16538176 NCBI chrNW_004936476:25,141,317...25,165,161 JBrowse link
G Ms4a2 membrane spanning 4-domains A2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16839402 PMID:18534082 PMID:20485159 NCBI chrNW_004936581:2,743,133...2,751,925 JBrowse link
G Nlrp3 NLR family pyrin domain containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19767079 NCBI chrNW_004936864:709,693...732,119 JBrowse link
G Postn periostin ISO CTD Direct Evidence: marker/mechanism CTD PMID:18391768 NCBI chrNW_004936472:31,644,778...31,677,572 JBrowse link
G Ptger3 prostaglandin E receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20587336 NCBI chrNW_004936591:1,174,364...1,250,233 JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17508966 NCBI chrNW_004936487:10,745,465...10,758,812 JBrowse link
G Tac1 tachykinin precursor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21233199 NCBI chrNW_004936585:2,932,783...2,941,141 JBrowse link
G Tbxas1 thromboxane A synthase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21449675 NCBI chrNW_004936592:4,038,163...4,192,772 JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:11294926 PMID:20485159 NCBI chrNW_004936727:1,936,066...1,937,766 JBrowse link
Drug Eruptions term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox5 arachidonate 5-lipoxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16502481 NCBI chrNW_004936554:7,807,914...7,848,691 JBrowse link
G Apoa1 apolipoprotein A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21055120 NCBI chrNW_004936542:2,111,055...2,112,626 JBrowse link
G Apoc2 apolipoprotein C2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21055120 NCBI chrNW_004936706:1,531,219...1,531,921 JBrowse link
G Apoc3 apolipoprotein C3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21055120 NCBI chrNW_004936542:2,106,927...2,108,412 JBrowse link
G Bdnf brain derived neurotrophic factor ISO mRNA:increased expression:lymph node, ear: RGD PMID:19904815 RGD:8657071 NCBI chrNW_004936540:5,530,081...5,582,765 JBrowse link
G Fcer1a Fc fragment of IgE receptor Ia ISO CTD Direct Evidence: marker/mechanism CTD PMID:16502481 NCBI chrNW_004936740:1,201,370...1,206,871 JBrowse link
G Ifng interferon gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:31150805 NCBI chrNW_004936545:6,139,130...6,144,543 JBrowse link
G Il17a interleukin 17A ISO CTD Direct Evidence: marker/mechanism CTD PMID:31150805 NCBI chrNW_004936476:8,621,860...8,625,008 JBrowse link
G Il18 interleukin 18 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18204966 NCBI chrNW_004936612:2,306,963...2,325,086 JBrowse link
G Il2 interleukin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31150805 NCBI chrNW_004936662:1,594,953...1,599,625 JBrowse link
G Kng1 kininogen 1 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:1371395 PMID:3034372 NCBI chrNW_004936578:3,255,335...3,281,296 JBrowse link
G LOC101963197 HLA class II histocompatibility antigen, DP beta 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:16502481 NCBI chrNW_004936476:25,730,800...25,741,089 JBrowse link
G LOC101969148 cytochrome P450 1A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19351467 NCBI chrNW_004936471:33,682,730...33,688,332 JBrowse link
G LOC101973029 cytochrome P450 2E1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19351467 NCBI chrNW_004936486:19,691,822...19,702,684 JBrowse link
G Mpo myeloperoxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:18204966 NCBI chrNW_004936490:4,809,773...4,819,070 JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:14723717 NCBI chrNW_004936474:623,438...637,849 JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:31150805 NCBI chrNW_004936599:3,800,142...3,810,583 JBrowse link
G Tac1 tachykinin precursor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:1371395 NCBI chrNW_004936585:2,932,783...2,941,141 JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:31150805 NCBI chrNW_004936727:1,936,066...1,937,766 JBrowse link
G Ttr transthyretin ISO CTD Direct Evidence: marker/mechanism CTD PMID:21055120 NCBI chrNW_004936682:1,628,489...1,635,495 JBrowse link
Drug Hypersensitivity Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1qa complement C1q A chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:34142820 NCBI chrNW_004936474:8,007,953...8,010,591 JBrowse link
G Il1b interleukin 1 beta ISO DNA:SNP:promoter:-511C>T (rs 16944) (human) RGD PMID:23461376 RGD:11051970 NCBI chrNW_004936783:1,251,678...1,256,807 JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO DNA:SNP:intron:rs2234663 (human) RGD PMID:23461376 RGD:11051970 NCBI chrNW_004936783:1,447,158...1,466,331 JBrowse link
G LOC101956412 heat shock 70 kDa protein 1-like ISO DNA:polymorphism, haplotype: :p.M493T (human) RGD PMID:15024131 RGD:8662461 NCBI chrNW_004936727:1,735,880...1,745,231 JBrowse link
G LOC101958966 lipopolysaccharide binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:34142820 NCBI chrNW_004936561:3,017,471...3,035,481 JBrowse link
G LOC101960229 complement C1q subcomponent subunit C ISO CTD Direct Evidence: marker/mechanism CTD PMID:34142820 NCBI chrNW_004936474:8,013,395...8,016,937 JBrowse link
G LOC101969640 C-reactive protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:34142820 NCBI chrNW_004936740:885,855...888,854 JBrowse link
G Lrg1 leucine rich alpha-2-glycoprotein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34142820 NCBI chrNW_004936588:2,638,597...2,640,856 JBrowse link
G Vwf von Willebrand factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:34142820 NCBI chrNW_004936709:1,578,137...1,741,877 JBrowse link
Drug-Induced Dyskinesia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase ISO RGD PMID:6445277 PMID:7740056 RGD:10047091 RGD:1598524 NCBI chrNW_004936530:7,543,743...7,621,392 JBrowse link
G Cacna1d calcium voltage-gated channel subunit alpha1 D ISO RGD PMID:18947822 RGD:6906919 NCBI chrNW_004936473:4,164,633...4,479,866 JBrowse link
G Cat catalase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19109989 NCBI chrNW_004936533:3,601,270...3,637,128 JBrowse link
G Cck cholecystokinin ISO CTD Direct Evidence: therapeutic CTD PMID:2320253 NCBI chrNW_004936695:2,776,705...2,782,280 JBrowse link
G Comt catechol-O-methyltransferase ISO RGD PMID:16437585 RGD:2289781 NCBI chrNW_004936619:3,847,059...3,883,866 JBrowse link
G Dbn1 drebrin 1 ISO levodopainduced; protein:increased expression:striatum: RGD PMID:23241013 RGD:10398811 NCBI chrNW_004936597:1,735,589...1,751,628 JBrowse link
G Ddc dopa decarboxylase ISO associated with Parkinson Disease; protein:decreased expression:striatum (rat) RGD PMID:20232137 RGD:5128860 NCBI chrNW_004936686:1,322,153...1,405,434 JBrowse link
G Drd1 dopamine receptor D1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:7845605 PMID:10858612 PMID:16982285 PMID:19520364 NCBI chrNW_004936609:790,647...795,187 JBrowse link
G Drd2 dopamine receptor D2 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:7845605 PMID:10534246 PMID:14629710 PMID:18707801 RGD:2311579 NCBI chrNW_004936612:1,094,686...1,154,149 JBrowse link
G Drd3 dopamine receptor D3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20945430 NCBI chrNW_004936536:1,580,732...1,616,726 JBrowse link
G Egr1 early growth response 1 ISO RGD PMID:22153973 RGD:10395307 NCBI chrNW_004936531:7,625,956...7,629,041 JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:17219962 NCBI chrNW_004936706:1,900,954...1,907,567 JBrowse link
G Gad1 glutamate decarboxylase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:9767399 NCBI chrNW_004936509:1,160,559...1,201,037 JBrowse link
G Gch1 GTP cyclohydrolase 1 ISO CTD Direct Evidence: therapeutic CTD PMID:15659429 NCBI chrNW_004936697:232,048...275,420 JBrowse link
G Gdnf glial cell derived neurotrophic factor ISO CTD Direct Evidence: therapeutic CTD PMID:11168568 NCBI chrNW_004936518:4,291,391...4,310,752 JBrowse link
G Glul glutamate-ammonia ligase ISO RGD PMID:6445277 RGD:10047091 NCBI chrNW_004936481:7,293,301...7,301,416 JBrowse link
G Grk6 G protein-coupled receptor kinase 6 ISO associated with Parkinson Disease RGD PMID:20410529 RGD:5684919 NCBI chrNW_004936597:1,706,671...1,722,370 JBrowse link
G Gsk3b glycogen synthase kinase 3 beta treatment ISO associated with Parkinsonian Disorders RGD PMID:26997328 RGD:13792768 NCBI chrNW_004936536:6,730,070...6,893,818 JBrowse link
G Homer1 homer scaffold protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24126708 NCBI chrNW_004936549:7,189,588...7,320,117 JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A ISO RGD PMID:21352823 RGD:5683628 NCBI chrNW_004936480:5,042,531...5,047,157 JBrowse link
G LOC101961588 cytochrome P450 2D17 ISO RGD PMID:12629505 RGD:1358549 NCBI chrNW_004936718:153,340...157,966 JBrowse link
G Mapt microtubule associated protein tau treatment ISO associated with Parkinsonian Disorders RGD PMID:25511986 RGD:13800920 NCBI chrNW_004936541:2,381,411...2,479,984 JBrowse link
G Mtor mechanistic target of rapamycin kinase treatment ISO associated with Parkinsonian Disorders RGD PMID:23938307 RGD:10040953 NCBI chrNW_004936474:158,376...282,310 JBrowse link
G Pdyn prodynorphin ISO CTD Direct Evidence: marker/mechanism CTD PMID:9767399 PMID:21737418 NCBI chrNW_004936485:16,559,371...16,571,461 JBrowse link
G Penk proenkephalin ISO mRNA:increased expression:brain:striatum:
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:9767399 PMID:20456008 RGD:10003039 NCBI chrNW_004936496:3,016,247...3,021,726 JBrowse link
G Ppp1r1b protein phosphatase 1 regulatory inhibitor subunit 1B treatment ISO associated with Parkinsonian Disorders RGD PMID:27771532 RGD:13514053 NCBI chrNW_004936490:14,822,246...14,831,337 JBrowse link
G Rasgrf1 Ras protein specific guanine nucleotide releasing factor 1 ISO CTD Direct Evidence: therapeutic CTD PMID:21115823 NCBI chrNW_004936471:37,173,595...37,278,356 JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit ISO protein:increased expression:nucleus, brain RGD PMID:18590723 RGD:2298778 NCBI chrNW_004936599:3,800,142...3,810,583 JBrowse link
G Rgs4 regulator of G protein signaling 4 treatment ISO associated with Parkinsonian Disorders RGD PMID:24969021 RGD:13524515 NCBI chrNW_004937238:101,948...109,513 JBrowse link
G Rgs9 regulator of G protein signaling 9 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:18160641 PMID:24663062 NCBI chrNW_004936541:7,472,195...7,525,220 JBrowse link
G Th tyrosine hydroxylase ISO CTD Direct Evidence: therapeutic CTD PMID:15659429 NCBI chrNW_004936794:478,651...486,887 JBrowse link
Drug-Induced Enteropathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nos3 nitric oxide synthase 3 treatment ISO RGD PMID:29064425 RGD:13450913 NCBI chrNW_004936527:6,427,147...6,445,770 JBrowse link
drug-induced hepatitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 no_association
susceptibility
ISO DNA:SNPs:multiple:
DNA:polymorphisms,haplotype:promoter:g.-1774delG,g.-1549G>A(human)
RGD PMID:17502832 PMID:22178260 RGD:14700816 RGD:14700817 NCBI chrNW_004936636:292,631...341,999 JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase ISO RGD PMID:16140414 RGD:2316848 NCBI chrNW_004936549:1,378,536...1,400,501 JBrowse link
G LOC101973029 cytochrome P450 2E1 ISO DNA:hypermethylation:promoter RGD PMID:23619520 RGD:14700910 NCBI chrNW_004936486:19,691,822...19,702,684 JBrowse link
G Lpar1 lysophosphatidic acid receptor 1 ISO protein:increased expression:liver (mouse) RGD PMID:12201952 RGD:10054288 NCBI chrNW_004936559:2,187,791...2,331,587 JBrowse link
erythema nodosum term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 ISO associated with Leprosy RGD PMID:2783924 RGD:7421527 NCBI chrNW_004936588:3,985,732...4,023,221 JBrowse link
G Cfb complement factor B ISO associated with Leprosy RGD PMID:2783924 RGD:7421527 NCBI chrNW_004936727:1,595,872...1,602,274 JBrowse link
G Lta lymphotoxin alpha ISO associated with Sarcoidosis;DNA:polymorphism:intron RGD PMID:19225544 RGD:8548773 NCBI chrNW_004936727:1,940,081...1,941,022 JBrowse link
G Tnf tumor necrosis factor susceptibility ISO associated with Inflammatory Bowel Diseases;DNA:polymorphisms: :-1031T>C(human) RGD PMID:12198697 RGD:7364926 NCBI chrNW_004936727:1,936,066...1,937,766 JBrowse link
G Vdr vitamin D receptor susceptibility ISO associated with Behcet Syndrome;DNA:polymorphism: : rs7975232(human) RGD PMID:24880677 RGD:13217417 NCBI chrNW_004936512:5,741,836...5,800,999 JBrowse link
Halothane Hepatitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpt glutamic--pyruvic transaminase treatment ISO RGD PMID:28921207 RGD:14975164 NCBI chrNW_004936470:7,765,810...7,770,837 JBrowse link
Hand-Foot Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kdr kinase insert domain receptor treatment ISO DNA:polymorphism:cds:p.H472Q(human) RGD PMID:20630084 RGD:8552374 NCBI chrNW_004936482:17,537,697...17,581,320 JBrowse link
NSAID-Enteropathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp9 caspase 9 ISO RGD PMID:25014874 RGD:13782349 NCBI chrNW_004936474:3,178,097...3,196,130 JBrowse link
G Ptger3 prostaglandin E receptor 3 treatment ISO RGD PMID:11991626 RGD:10003093 NCBI chrNW_004936591:1,174,364...1,250,233 JBrowse link
G Ptger4 prostaglandin E receptor 4 treatment ISO RGD PMID:11991626 RGD:10003093 NCBI chrNW_004936518:1,903,636...1,916,746 JBrowse link
Poor Metabolism of Thiopurines, 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tpmt thiopurine S-methyltransferase ISO OMIM NCBI chrNW_004936552:3,899,445...3,917,774 JBrowse link
Poor Metabolism of Thiopurines, 2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nudt15 nudix hydrolase 15 ISO ClinVar Annotator: match by term: Thiopurines, poor metabolism of, 2 OMIM
ClinVar
PMID:22992668 PMID:25108385 PMID:25624441 PMID:26033531 PMID:26076924 More... NCBI chrNW_004936565:1,380,981...1,389,908 JBrowse link
Serotonin Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cabp1 calcium binding protein 1 ISO protein:altered expression:postsynaptic density RGD PMID:19224364 RGD:14399959 NCBI chrNW_004936668:324,299...339,334 JBrowse link
Stevens-Johnson syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apcs amyloid P component, serum ISO CTD Direct Evidence: marker/mechanism CTD PMID:34142820 NCBI chrNW_004936740:979,007...987,312 JBrowse link
G C1qa complement C1q A chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:34142820 NCBI chrNW_004936474:8,007,953...8,010,591 JBrowse link
G Cav1 caveolin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25811541 NCBI chrNW_004936589:2,504,235...2,536,778 JBrowse link
G Celf2 CUGBP Elav-like family member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25811541 NCBI chrNW_004936484:3,904,726...4,401,560 JBrowse link
G Clu clusterin ISO mRNA:decreased expression:conjunctiva RGD PMID:12036968 RGD:8699507 NCBI chrNW_004936675:499,745...513,515 JBrowse link
G Cops5 COP9 signalosome subunit 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25811541 NCBI chrNW_004936496:7,035,973...7,050,538 JBrowse link
G Csf3 colony stimulating factor 3 ISO CTD Direct Evidence: therapeutic CTD PMID:11321886 NCBI chrNW_004936490:15,142,526...15,146,375 JBrowse link
G Ctnnb1 catenin beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25811541 NCBI chrNW_004936473:29,999,542...30,034,610 JBrowse link
G Cul1 cullin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25811541 NCBI chrNW_004936527:4,971,002...5,019,465 JBrowse link
G Cul4a cullin 4A ISO CTD Direct Evidence: marker/mechanism CTD PMID:25811541 NCBI chrNW_004936472:409,083...432,442 JBrowse link
G Derl1 derlin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25811541 NCBI chrNW_004936470:24,262,401...24,286,713 JBrowse link
G Elmo1 engulfment and cell motility 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25811541 NCBI chrNW_004936478:12,308,255...12,754,957 JBrowse link
G Ep300 E1A binding protein p300 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25811541 NCBI chrNW_004936492:696,982...778,132 JBrowse link
G Fbxo6 F-box protein 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25811541 NCBI chrNW_004936474:531,873...538,596 JBrowse link
G Ifng interferon gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:25811541 NCBI chrNW_004936545:6,139,130...6,144,543 JBrowse link
G LOC101958966 lipopolysaccharide binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:34142820 NCBI chrNW_004936561:3,017,471...3,035,481 JBrowse link
G LOC101960229 complement C1q subcomponent subunit C ISO CTD Direct Evidence: marker/mechanism CTD PMID:34142820 NCBI chrNW_004936474:8,013,395...8,016,937 JBrowse link
G LOC101961626 complement factor properdin ISO CTD Direct Evidence: marker/mechanism CTD PMID:34142820 NCBI chrNW_004936502:13,391,613...13,398,723 JBrowse link
G LOC101969640 C-reactive protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:34142820 NCBI chrNW_004936740:885,855...888,854 JBrowse link
G LOC101972576 valosin containing protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:25811541 NCBI chrNW_004936524:3,085,959...3,102,461 JBrowse link
G Lrg1 leucine rich alpha-2-glycoprotein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34142820 NCBI chrNW_004936588:2,638,597...2,640,856 JBrowse link
G Mif macrophage migration inhibitory factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:9372356 NCBI chrNW_004936619:1,207,058...1,208,010 JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25811541 NCBI chrNW_004936471:17,254,777...17,374,725 JBrowse link
G Nos2 nitric oxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10620138 NCBI chrNW_004936538:4,052,277...4,097,051 JBrowse link
G Nucb1 nucleobindin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25811541 NCBI chrNW_004936664:2,924,186...2,946,035 JBrowse link
G Parp1 poly(ADP-ribose) polymerase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25811541 NCBI chrNW_004936526:3,102,468...3,147,601 JBrowse link
G Pml PML nuclear body scaffold ISO CTD Direct Evidence: marker/mechanism CTD PMID:25811541 NCBI chrNW_004936471:33,135,186...33,173,218 JBrowse link
G Pros1 protein S ISO CTD Direct Evidence: marker/mechanism CTD PMID:34142820 NCBI chrNW_004936666:18,303...110,357 JBrowse link
G Psmc5 proteasome 26S subunit, ATPase 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25811541 NCBI chrNW_004936541:4,470,210...4,475,233 JBrowse link
G Ptger3 prostaglandin E receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21966456 NCBI chrNW_004936591:1,174,364...1,250,233 JBrowse link
G Ptgis prostaglandin I2 synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25811541 NCBI chrNW_004936514:4,775,884...4,814,574 JBrowse link
G Rb1 RB transcriptional corepressor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25811541 NCBI chrNW_004936565:1,596,227...1,746,706 JBrowse link
G Rbx1 ring-box 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25811541 NCBI chrNW_004936492:872,316...890,860 JBrowse link
G Tnf tumor necrosis factor ISO protein:increased expression:blister: RGD PMID:9852250 RGD:7401184 NCBI chrNW_004936727:1,936,066...1,937,766 JBrowse link
G Vwf von Willebrand factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:34142820 NCBI chrNW_004936709:1,578,137...1,741,877 JBrowse link
Tardive Dyskinesia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd3 dopamine receptor D3 ISO associated with schizophrenia RGD PMID:12960753 RGD:1581250 NCBI chrNW_004936536:1,580,732...1,616,726 JBrowse link
G LOC101969421 cytochrome P450 1A2 treatment ISO associated with schizophrenia RGD PMID:10889552 RGD:1358545 NCBI chrNW_004936471:33,704,616...33,709,455 JBrowse link
G Sod2 superoxide dismutase 2 ISO associated with schizophrenia RGD PMID:12960753 RGD:1581250 NCBI chrNW_004936489:11,178,338...11,191,601 JBrowse link
thiopurine S-methyltransferase deficiency term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tpmt thiopurine S-methyltransferase ISO ClinVar Annotator: match by term: Thiopurine methyltransferase deficiency ClinVar PMID:1960624 PMID:7862671 PMID:8561894 PMID:8644731 PMID:9177237 More... NCBI chrNW_004936552:3,899,445...3,917,774 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 13689
    Chemically-Induced Disorders 961
      Drug-Related Side Effects and Adverse Reactions 482
        Akathisia, Drug-Induced 0
        Anticholinergic Syndrome 0
        Cardiotoxicity + 22
        Chemical and Drug Induced Liver Injury + 311
        Chemotherapy-Related Cognitive Impairment 0
        Chloramphenicol Toxicity 0
        Drug-Induced Dyskinesia + 33
        Drug-Induced Enteropathy + 4
        Efavirenz, Poor Metabolism of 0
        Metabolic Side Effects of Drugs and Substances 0
        Myotoxicity 0
        Propofol Infusion Syndrome 0
        Serotonin Syndrome 1
        drug allergy + 97
paths to the root