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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Experimental Autoimmune Uveoretinitis
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Accession:DOID:9006642 term browser browse the term
Definition:An experimental animal model use for the study of retinitis combined with uveitis. It is commonly induced with interphotoreceptor retinoid-binding protein (IRBP) (relapsing EAU) or retinal S-Antigen (monophasic EAU).
Synonyms:exact_synonym: EAU
 primary_id: RDO:9000024
For additional species annotation, visit the Alliance of Genome Resources.



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Experimental Autoimmune Uveoretinitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace2 angiotensin I converting enzyme 2 treatment ISO human gene in a mouse model RGD PMID:25228068 RGD:40818264 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977
JBrowse link
G C3 complement C3 ISO RGD PMID:16143328 RGD:7401262 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 ISO mRNA:increased expression:eye: RGD PMID:12605265 RGD:8661671 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 ISO mRNA:increased expression:eye: RGD PMID:12605265 RGD:8661671 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
JBrowse link
G Cd40lg CD40 ligand treatment ISO RGD PMID:15972638 RGD:8547777 NCBI chr  X:135,127,119...135,138,302
Ensembl chr  X:135,126,969...135,138,306
JBrowse link
G Cfb complement factor B treatment ISO
IMP
RGD PMID:20806290 PMID:21216963 RGD:7411717, RGD:7411732 NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505
JBrowse link
G Icam1 intercellular adhesion molecule 1 treatment IMP RGD PMID:7909311 RGD:8547706 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Ifng interferon gamma IEP mRNA,protein:increased expression:eye: RGD PMID:1572694 RGD:8142388 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il10 interleukin 10 treatment ISO
IDA
RGD PMID:22629453 PMID:21296818 PMID:15240742 PMID:11359436 RGD:7364830, RGD:7364849, RGD:7365075, RGD:7365084 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il2 interleukin 2 disease_progression ISO
IEP
mRNA:increased expression:uvea: RGD PMID:7929845 PMID:7803357 RGD:8662951, RGD:8662946 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il4 interleukin 4 disease_progression IEP mRNA:increased expression:uvea: RGD PMID:7803357 RGD:8662946 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO RGD PMID:18424728 RGD:8694299 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A ISO RGD PMID:19635911 RGD:8661744 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 18133
    Animal Diseases 1692
      Animal Disease Models 1640
        Experimental Autoimmune Uveitis 35
          Experimental Autoimmune Uveoretinitis 14
Path 2
Term Annotations click to browse term
  disease 18133
    disease of anatomical entity 17503
      nervous system disease 13174
        sensory system disease 6388
          eye disease 2927
            uveal disease 232
              uveitis 142
                Experimental Autoimmune Uveitis 35
                  Experimental Autoimmune Uveoretinitis 14
paths to the root