Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Fatigue
go back to main search page
Accession:DOID:9006617 term browser browse the term
Definition:The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli.
Synonyms:exact_synonym: Lassitude
 primary_id: MESH:D005221

GViewer not supported for the selected species.

show annotations for term's descendants           Sort by:
Fatigue term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALAD aminolevulinate dehydratase ISO mRNA, protein:decreased expression:liver (rat) RGD PMID:17204241 RGD:1599013 NCBI chr12:26,173,063...26,185,456
Ensembl chr12:26,173,096...26,189,845 		JBrowse link
G COMT catechol-O-methyltransferase severity ISO associated with breast cancer;DNA:missense mutation:cds:p.V158M (human) RGD PMID:21898113 RGD:8662332 NCBI chr19:5,775,829...5,803,260
Ensembl chr19:5,773,225...5,785,422 		JBrowse link
G EPO erythropoietin ISO CTD Direct Evidence: therapeutic CTD PMID:18695134 NCBI chr28:12,487,222...12,491,986
Ensembl chr28:12,489,766...12,491,908 		JBrowse link
G IFNA2 interferon alpha 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8759893 NCBI chr12:58,468,018...58,469,825 JBrowse link
G SOD1 superoxide dismutase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28123103 NCBI chr 2:60,461,219...60,472,999 JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16885183 NCBI chr15:75,112,903...75,200,263
Ensembl chr15:75,112,561...75,197,711 		JBrowse link
G TNFRSF10A TNF receptor superfamily member 10a ISO CTD Direct Evidence: marker/mechanism CTD PMID:19652058 NCBI chr 8:21,318,987...21,351,641
Ensembl chr 8:21,315,149...21,351,673 		JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B ISO protein:increased expression:serum RGD PMID:12140350 RGD:8661748 NCBI chr20:119,590,621...119,633,562
Ensembl chr20:119,590,325...119,633,497 		JBrowse link
corticosteroid-binding globulin deficiency term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SERPINA6 serpin family A member 6 ISO ClinVar Annotator: match by term: Corticosteroid-binding globulin deficiency | ClinVar Annotator: match by term: SERPINA6-related condition | ClinVar Annotator: match by term: TRANSCORTIN DEFICIENCY OMIM
ClinVar		 PMID:1504007 PMID:7061486 PMID:8212073 PMID:10634411 PMID:11502797 More... NCBI chr24:72,079,084...72,098,549
Ensembl chr24:72,077,274...72,098,154 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15416
    Pathological Conditions, Signs and Symptoms 12061
      Signs and Symptoms 10141
        Fatigue 9
          Mental Fatigue + 0
          corticosteroid-binding globulin deficiency 1
paths to the root