Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Enterovirus Infections
go back to main search page
Accession:DOID:9006549 term browser browse the term
Definition:Diseases caused by ENTEROVIRUS.
Synonyms:exact_synonym: Enterovirus Infection
 primary_id: MESH:D004769;   RDO:0001633
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
 
Enterovirus Infections term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BTK Bruton tyrosine kinase treatment ISO Associated with X-linked agammaglobulinemia RGD PMID:10508272 RGD:124715472 NCBI chr  X:82,981,512...83,014,475
Ensembl chr  X:82,981,515...83,014,573
JBrowse link
G COG1 component of oligomeric golgi complex 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28446605 NCBI chr12:7,745,928...7,760,539
Ensembl chr12:7,743,060...7,760,504
JBrowse link
G COG5 component of oligomeric golgi complex 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28446605 NCBI chr 9:106,993,771...107,273,889
Ensembl chr 9:106,990,573...107,273,607
JBrowse link
G IL10 interleukin 10 severity ISO DNA:SNP:promoter:-592A>C (rs1800872) (human) RGD PMID:28843383 RGD:14975146 NCBI chr 9:67,400,727...67,405,941
Ensembl chr 9:67,400,727...67,405,711
JBrowse link
G MGAT5 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:28446605 NCBI chr15:17,544,806...17,919,273
Ensembl chr15:17,544,806...17,918,944
JBrowse link
G MX1 MX dynamin like GTPase 1 susceptibility ISO DNA:SNPs:promoter:g.-123C>A, g.-88G>T (rs17000900, rs2071430) (human) RGD PMID:24085612 RGD:126777678 NCBI chr13:204,843,049...204,868,927
Ensembl chr13:204,843,754...204,868,922
JBrowse link
G SLC22A4 solute carrier family 22 member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21641380 NCBI chr 2:134,594,843...134,641,403
Ensembl chr 2:134,595,536...134,640,723
JBrowse link
G ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28446605 NCBI chr 4:7,814,492...7,911,053
Ensembl chr 4:7,814,694...7,909,528
JBrowse link
G ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28446605 NCBI chr 9:53,442,795...53,491,847
Ensembl chr 9:53,445,591...53,486,010
JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A ISO Rhinovirus Infections RGD PMID:19864593 RGD:5131210 NCBI chr 5:64,319,349...64,331,876
Ensembl chr 5:64,319,073...64,331,909
JBrowse link
anogenital venereal wart term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL20 C-C motif chemokine ligand 20 ISO protein:decreased expression:skin RGD PMID:17545018 RGD:7483603 NCBI chr15:129,172,743...129,176,069 JBrowse link
G CD8A CD8a molecule ISO mRNA:decreased expression:zone of skin (human) RGD PMID:25774455 RGD:36174028 NCBI chr 3:57,999,228...58,029,768
Ensembl chr 3:57,998,891...58,037,130
JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 ISO mRNA,protein:increased expression:multiple (human) RGD PMID:23754510 RGD:40400714 NCBI chr15:107,283,081...107,288,041
Ensembl chr15:107,282,926...107,289,103
JBrowse link
G FOXP3 forkhead box P3 ISO mRNA,protein:increased expression:multiple (human) RGD PMID:23754510 RGD:40400714 NCBI chr  X:43,303,777...43,328,164
Ensembl chr  X:43,303,782...43,328,735
JBrowse link
G IL10 interleukin 10 ISO mRNA,protein:increased expression:multiple (human) RGD PMID:23754510 RGD:40400714 NCBI chr 9:67,400,727...67,405,941
Ensembl chr 9:67,400,727...67,405,711
JBrowse link
G IL12B interleukin 12B treatment ISO protein:decreased expression:peripheral blood mononuclear cells (human) RGD PMID:16114559 PMID:23754510 RGD:40400714 RGD:7829774 NCBI chr16:64,143,268...64,158,929
Ensembl chr16:64,147,247...64,158,952
JBrowse link
G IL2 interleukin 2 ISO protein:decreased expression:peripheral blood mononuclear cells (human) RGD PMID:23754510 RGD:40400714 NCBI chr 8:101,640,938...101,645,683
Ensembl chr 8:101,640,944...101,645,609
JBrowse link
G IL21 interleukin 21 ISO protein:decreased expression:blood serum (human) RGD PMID:31414711 RGD:127285371 NCBI chr 8:101,532,742...101,540,712
Ensembl chr 8:101,530,949...101,540,738
JBrowse link
G IL4 interleukin 4 treatment ISO protein:increased expression:peripheral blood mononuclear cells (human) RGD PMID:16114559 PMID:23754510 RGD:40400714 RGD:7829774 NCBI chr 2:134,986,817...134,994,365
Ensembl chr 2:134,986,817...134,994,365
JBrowse link
G IL6 interleukin 6 ISO protein:decreased expression:peripheral blood mononuclear cells (human) RGD PMID:23754510 RGD:40400714 NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,340...91,511,263
JBrowse link
G KLRK1 killer cell lectin like receptor K1 ISO mRNA,protein:decreased expression:multiple (human) RGD PMID:23754510 RGD:40400714 NCBI chr 5:61,646,691...61,655,386
Ensembl chr 5:61,623,200...61,656,195
JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor ISO mRNA,protein:increased expression:multiple (human) RGD PMID:23754510 RGD:40400714 NCBI chr13:22,976,951...22,979,568
Ensembl chr13:22,964,071...22,983,109
JBrowse link
G NCR1 natural cytotoxicity triggering receptor 1 ISO mRNA,protein:decreased expression:multiple (human) RGD PMID:23754510 RGD:40400714 NCBI chr 6:59,092,258...59,099,992
Ensembl chr 6:59,092,655...59,099,992
JBrowse link
G PDCD1 programmed cell death 1 ISO mRNA,protein:increased expression:multiple (human) RGD PMID:23754510 RGD:40400714 NCBI chr15:140,337,353...140,347,493
Ensembl chr15:140,336,210...140,347,478
JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 ISO protein:increased expression:foreskin RGD PMID:18543080 RGD:39128248 NCBI chr14:39,202,165...39,292,041
Ensembl chr14:39,202,168...39,292,018
JBrowse link
G PTPN6 protein tyrosine phosphatase non-receptor type 6 ISO protein:increased expression:foreskin RGD PMID:18543080 RGD:39128248 NCBI chr 5:63,762,109...63,779,086
Ensembl chr 5:63,762,112...63,808,350
JBrowse link
G SERPINF1 serpin family F member 1 disease_progression ISO mRNA, protein:decreased expression:skin of body (human) RGD PMID:23569025 RGD:27226706 NCBI chr12:47,949,004...47,959,471
Ensembl chr12:47,943,051...47,959,472
JBrowse link
G TGFB1 transforming growth factor beta 1 ISO mRNA,protein:increased expression:multiple (human) RGD PMID:23754510 RGD:40400714 NCBI chr 6:49,332,169...49,348,642
Ensembl chr 6:49,332,169...49,349,048
JBrowse link
G TLR2 toll like receptor 2 ISO mRNA,protein:increased expression:multiple (human) RGD PMID:23754510 RGD:40400714 NCBI chr 8:75,416,257...75,428,370
Ensembl chr 8:75,411,991...75,446,850
JBrowse link
G TLR3 toll like receptor 3 ISO mRNA,protein:increased expression:multiple (human) RGD PMID:23754510 RGD:40400714 NCBI chr15:46,966,262...46,977,774
Ensembl chr15:46,966,040...47,058,734
JBrowse link
G TLR4 toll like receptor 4 ISO mRNA,protein:increased expression:multiple (human) RGD PMID:23754510 RGD:40400714 NCBI chr 1:258,044,610...258,054,641
Ensembl chr 1:258,044,610...258,059,004
JBrowse link
G TLR8 toll like receptor 8 ISO mRNA,protein:increased expression:multiple (human) RGD PMID:23754510 RGD:40400714 NCBI chr  X:9,551,284...9,616,762
Ensembl chr  X:9,549,552...9,616,759
JBrowse link
G TLR9 toll like receptor 9 ISO mRNA,protein:increased expression:multiple (human) RGD PMID:23754510 RGD:40400714 NCBI chr13:34,353,444...34,370,990 JBrowse link
G TNF tumor necrosis factor ISO protein:increased expression:peripheral blood mononuclear cells (human) RGD PMID:23754510 RGD:40400714 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,636...23,703,655
JBrowse link
G TNFRSF18 TNF receptor superfamily member 18 ISO mRNA,protein:increased expression:multiple (human) RGD PMID:23754510 RGD:40400714 NCBI chr 6:63,516,037...63,519,323 JBrowse link
Coxsackievirus Infections term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD274 CD274 molecule treatment ISO RGD PMID:30904424 RGD:40818421 NCBI chr 1:216,646,378...216,792,731
Ensembl chr 1:216,660,047...216,792,724
JBrowse link
G IL6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25396421 NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,340...91,511,263
JBrowse link
G PCD1B CD1B antigen ISO protein:increased expression:spleen, mononuclear cell (mouse) RGD PMID:16817758 RGD:127345109 NCBI chr 4:92,035,122...92,040,724 JBrowse link
G PDCD1LG2 programmed cell death 1 ligand 2 treatment ISO RGD PMID:30904424 RGD:40818421 NCBI chr 1:216,564,428...216,600,333
Ensembl chr 1:216,553,101...216,682,607
JBrowse link
G SIVA1 SIVA1 apoptosis inducing factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:16683188
G SLC22A3 solute carrier family 22 member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21641380 NCBI chr 1:7,105,486...7,207,395
Ensembl chr 1:7,110,072...7,207,402
JBrowse link
G SLC22A4 solute carrier family 22 member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21641380 NCBI chr 2:134,594,843...134,641,403
Ensembl chr 2:134,595,536...134,640,723
JBrowse link
G SLC22A5 solute carrier family 22 member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21641380 NCBI chr 2:134,660,741...134,847,575 JBrowse link
G TNF tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:25396421 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,636...23,703,655
JBrowse link
G TNFSF8 TNF superfamily member 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11745696 NCBI chr 1:255,436,206...255,459,020
Ensembl chr 1:255,432,969...255,459,073
JBrowse link
G TNFSF9 TNF superfamily member 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11745696 NCBI chr 2:72,578,811...72,582,834
Ensembl chr 2:72,578,821...72,582,745
JBrowse link
hand, foot and mouth disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTB actin beta ISO protein:increased expression:serum RGD PMID:30817906 RGD:36947391 NCBI chr 3:4,084,275...4,090,383
Ensembl chr 3:4,082,216...4,090,356
JBrowse link
G REN renin treatment ISO RGD PMID:31638922 RGD:127285374 NCBI chr 9:64,809,143...64,822,605
Ensembl chr 9:64,809,146...64,822,636
JBrowse link
hepatitis A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 ISO DNA:insertion/deletion:intron 16: RGD PMID:12458570 RGD:39939119 NCBI chr12:15,394,487...15,414,609
Ensembl chr12:15,394,487...15,414,639
JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 disease_progression ISO RGD PMID:26347518 RGD:40818419 NCBI chr15:107,283,081...107,288,041
Ensembl chr15:107,282,926...107,289,103
JBrowse link
G PDCD1 programmed cell death 1 disease_progression ISO RGD PMID:26347518 RGD:40818419 NCBI chr15:140,337,353...140,347,493
Ensembl chr15:140,336,210...140,347,478
JBrowse link
G TNF tumor necrosis factor ISO protein:increased expression:serum (human) RGD PMID:9047083 RGD:14995307 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,636...23,703,655
JBrowse link
G XRCC1 X-ray repair cross complementing 1 susceptibility ISO DNA:missense mutation:cds:p.R194W (rs1799782) (human)
DNA:SNP:intron: (rs1001581) (human)
RGD PMID:22135187 PMID:29558945 RGD:15014793 RGD:15036793 NCBI chr 6:50,403,691...50,425,730
Ensembl chr 6:50,403,686...50,425,710
JBrowse link
Keshan disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 ISO mRNA,protein:increased expression:blood cells, serum: RGD PMID:26893848 RGD:124713562 NCBI chr 7:58,802,887...58,809,155
Ensembl chr 7:58,780,105...58,809,755
JBrowse link
G CYP2C49 cytochrome P450 2C49 ISO mRNA,protein:increased expression:blood cells, serum: RGD PMID:26893848 RGD:124713562 NCBI chr14:106,571,803...106,612,082 JBrowse link
G GPX1 glutathione peroxidase 1 ISO DNA:polymorphism: :p.P198L (human) RGD PMID:21055077 RGD:11352821 NCBI chr13:31,916,269...31,917,337
Ensembl chr13:31,914,932...31,917,335
JBrowse link
poliomyelitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PVR PVR cell adhesion molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:3020560 PMID:28446605 NCBI chr 6:51,161,320...51,178,464 JBrowse link
vestibular neuronitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CRP C-reactive protein, pentraxin-related disease_progression ISO RGD PMID:14636287 RGD:9491594 NCBI chr 4:90,793,361...90,801,020
Ensembl chr 4:90,722,352...90,805,236
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 13552
    disease by infectious agent 1777
      viral infectious disease 1485
        RNA Virus Infections 1294
          Picornaviridae Infections 72
            Enterovirus Infections 51
              Coxsackievirus Infections + 36
              Echovirus Infections + 25
              Encephalomyelitis, Enzootic Porcine 0
              Keshan disease 3
              Swine Vesicular Disease 0
              acute hemorrhagic conjunctivitis 0
              hepatitis A 5
              poliomyelitis + 2
paths to the root