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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Hematologic Neoplasms
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Accession:DOID:9006532 term browser browse the term
Definition:Neoplasms located in the blood and blood-forming tissue (the bone marrow and lymphatic tissue). The commonest forms are the various types of LEUKEMIA, of LYMPHOMA, and of the progressive, life-threatening forms of the MYELODYSPLASTIC SYNDROMES.
Synonyms:exact_synonym: Hematological Neoplasms;   Hematopoietic Malignancies;   Hematopoietic Malignancy;   hematologic neoplasm;   hematological neoplasm;   hematopoietic neoplasm;   hematopoietic neoplasms
 primary_id: MESH:D019337
 alt_id: RDO:0007251
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
 
Hematologic Neoplasms term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22311042 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
Ensembl chr 7:87,503,017...87,713,323
JBrowse link
G ABO ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase susceptibility IDA RGD PMID:19274076 RGD:11100003 NCBI chr 9:133,250,401...133,275,201
Ensembl chr 9:133,250,401...133,276,024
Ensembl chr 9:133,250,401...133,276,024
JBrowse link
G CBL Cbl proto-oncogene IAGP ClinVar Annotator: match by term: Hematologic neoplasm ClinVar PMID:19571318 PMID:20543203 PMID:20694012 PMID:23696637 PMID:25283271 PMID:25952305 PMID:28414188 PMID:28492532 NCBI chr11:119,206,339...119,308,149
Ensembl chr11:119,206,298...119,313,926
Ensembl chr11:119,206,298...119,313,926
JBrowse link
G CSF1R colony stimulating factor 1 receptor IAGP ClinVar Annotator: match by term: Hematologic neoplasm ClinVar PMID:2406720 PMID:18971950 PMID:25157968 NCBI chr 5:150,053,295...150,113,365
Ensembl chr 5:150,053,291...150,113,372
JBrowse link
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 treatment IAGP DNA:polymorphism: : RGD PMID:21108329 RGD:11352750 NCBI chr10:94,762,681...94,855,547
Ensembl chr10:94,762,681...94,855,547
JBrowse link
G ETV6 ETS variant transcription factor 6 IAGP
EXP
DNA:translocation: :
ClinVar Annotator: match by term: Hematologic neoplasm
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
PMID:25581430 PMID:25807284 PMID:31248877, PMID:11319801 RGD:10450600 NCBI chr12:11,649,601...11,895,386
Ensembl chr12:11,649,674...11,895,377
Ensembl chr12:11,649,674...11,895,377
JBrowse link
G GSTM1 glutathione S-transferase mu 1 susceptibility
no_association
IAGP associated with Breast Neoplasms; RGD PMID:11792413, PMID:10383893 RGD:10450857, RGD:10755329 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039
JBrowse link
G GSTT1 glutathione S-transferase theta 1 susceptibility IAGP associated with Breast Neoplasms; RGD PMID:11792413 RGD:10450857
G HSPA5 heat shock protein family A (Hsp70) member 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23777986 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,343
JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase IAGP ClinVar Annotator: match by term: Hematologic neoplasm
ClinVar Annotator: match by term: Hematological neoplasm
ClinVar PMID:7479840 PMID:7513208 PMID:7530509 PMID:7691885 PMID:8589724 PMID:9438854 PMID:9657776 PMID:9827716 PMID:9990072 PMID:10362788 PMID:11073817 PMID:11276010 PMID:11380399 PMID:11493470 PMID:11526490 PMID:15790786 PMID:15972446 PMID:16352739 PMID:16384925 PMID:16731599 PMID:16741525 PMID:16908931 PMID:16912224 PMID:17259998 PMID:17372901 PMID:17824795 PMID:18024392 PMID:18510589 PMID:18955458 PMID:18980976 PMID:18986703 PMID:19164557 PMID:19262599 PMID:19865100 PMID:20147452 PMID:20545949 PMID:21642685 PMID:21689725 PMID:21690468 PMID:22504184 PMID:23582185 PMID:23714533 PMID:24045550 PMID:25157968 PMID:25741868 PMID:26158763 PMID:26619011 PMID:26822237 PMID:27777718 PMID:28492532 NCBI chr 4:54,657,957...54,740,715
Ensembl chr 4:54,657,918...54,740,715
JBrowse link
G MEFV MEFV innate immuity regulator, pyrin susceptibility IAGP DNA:mutations:cds:p.M694V,E148Q,M680I(human) RGD PMID:20518828 RGD:11531118 NCBI chr16:3,242,027...3,256,776
Ensembl chr16:3,242,027...3,256,633
Ensembl chr16:3,242,027...3,256,633
JBrowse link
G MPL MPL proto-oncogene, thrombopoietin receptor IAGP ClinVar Annotator: match by term: Hematologic neoplasm ClinVar PMID:16834459 PMID:16868251 PMID:25741868 NCBI chr 1:43,336,875...43,354,466
Ensembl chr 1:43,337,818...43,354,466
Ensembl chr 1:43,337,818...43,354,466
JBrowse link
G MTHFR methylenetetrahydrofolate reductase treatment
no_association
IAGP DNA:SNP: :1298A>C (human)
DNA:SNP: :677C>T (human)
RGD PMID:21984221, PMID:21984221 RGD:10449413, RGD:10449413 NCBI chr 1:11,785,723...11,806,103
Ensembl chr 1:11,785,723...11,806,455
Ensembl chr 1:11,785,723...11,806,455
JBrowse link
G MUC1 mucin 1, cell surface associated IEP associated with Pneumonia, Pneumocystis; protein:increased expression:serum RGD PMID:12186700 RGD:5131276 NCBI chr 1:155,185,824...155,192,915
Ensembl chr 1:155,185,824...155,192,916
JBrowse link
G PON1 paraoxonase 1 susceptibility IAGP
EXP
DNA:missense mutation:cds:p.Q192R (human)
CTD Direct Evidence: marker/mechanism
CTD PMID:22800774, PMID:22800774 RGD:11552572 NCBI chr 7:95,297,676...95,324,532
Ensembl chr 7:95,297,676...95,324,532
JBrowse link
Acute Erythroleukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DDX41 DEAD-box helicase 41 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30926971 NCBI chr 5:177,511,577...177,516,961
Ensembl chr 5:177,511,577...177,516,961
JBrowse link
G ERBB3 erb-b2 receptor tyrosine kinase 3 IAGP ClinVar Annotator: match by term: Acute erythroleukemia ClinVar PMID:27416908 NCBI chr12:56,080,108...56,103,505
Ensembl chr12:56,076,799...56,103,505
JBrowse link
G FLT3 fms related receptor tyrosine kinase 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30926971 NCBI chr13:28,003,274...28,100,587
Ensembl chr13:28,003,274...28,100,592
JBrowse link
G GFI1B growth factor independent 1B transcriptional repressor IEP mRNA:increased expression:bone marrow cell: RGD PMID:17156408 RGD:11040507 NCBI chr 9:132,945,531...132,991,697
Ensembl chr 9:132,944,000...132,991,687
JBrowse link
G HOXB9 homeobox B9 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30926971 NCBI chr17:48,621,156...48,626,358
Ensembl chr17:48,621,156...48,626,358
JBrowse link
G KMT2A lysine methyltransferase 2A EXP CTD Direct Evidence: marker/mechanism CTD PMID:30926971 NCBI chr11:118,436,492...118,526,832
Ensembl chr11:118,436,490...118,526,832
JBrowse link
G NPM1 nucleophosmin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30926971 NCBI chr 5:171,387,116...171,410,900
Ensembl chr 5:171,387,116...171,411,137
Ensembl chr 5:171,387,116...171,411,137
JBrowse link
G NUP98 nucleoporin 98 and 96 precursor EXP CTD Direct Evidence: marker/mechanism CTD PMID:30926971 NCBI chr11:3,675,010...3,797,554
Ensembl chr11:3,671,083...3,797,792
JBrowse link
G RB1 RB transcriptional corepressor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30926971 NCBI chr13:48,303,751...48,481,890
Ensembl chr13:48,303,744...48,599,436
Ensembl chr13:48,303,744...48,599,436
JBrowse link
G TP53 tumor protein p53 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30926971 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
Ensembl chr17:7,661,779...7,687,538
JBrowse link
acute leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit IAGP ClinVar Annotator: match by term: Mixed Phenotype Acute Leukemia, T/Myeloid, Not Otherwise Specified ClinVar PMID:7585650 PMID:9195225 PMID:22234153 PMID:23221806 PMID:23232694 PMID:24728327 PMID:25716912 PMID:25741868 NCBI chr19:45,349,837...45,370,647
Ensembl chr19:45,349,837...45,370,918
JBrowse link
acute lymphoblastic leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 susceptibility IAGP
EXP
DNA:snps, haplotype:multiple (human)
CTD Direct Evidence: marker/mechanism
CTD PMID:22674224, PMID:22674224 RGD:8657089 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
Ensembl chr 7:87,503,017...87,713,323
JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 treatment IAGP DNA:SNP:5'UTR:rs717620(human)
DNA:SNPs: :rs717620(human)
RGD PMID:24404132, PMID:25007187 RGD:11080959, RGD:11080979 NCBI chr10:99,782,602...99,853,741
Ensembl chr10:99,782,640...99,852,594
JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 (Junior blood group) disease_progression IEP mRNA:increased expression:mononuclear cell: RGD PMID:15521915, PMID:12100141 RGD:11081076, RGD:11081143 NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628
JBrowse link
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase EXP CTD Direct Evidence: marker/mechanism CTD PMID:11984797 PMID:21898527 NCBI chr 9:130,713,043...130,887,675
Ensembl chr 9:130,713,016...130,887,675
JBrowse link
G ABO ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase susceptibility IAGP RGD PMID:17065136 RGD:11100012 NCBI chr 9:133,250,401...133,275,201
Ensembl chr 9:133,250,401...133,276,024
Ensembl chr 9:133,250,401...133,276,024
JBrowse link
G AICDA activation induced cytidine deaminase treatment IEP RGD PMID:19759560 RGD:11039451 NCBI chr12:8,602,170...8,612,970
Ensembl chr12:8,602,170...8,612,867
JBrowse link
G ARID5B AT-rich interaction domain 5B EXP CTD Direct Evidence: marker/mechanism CTD PMID:19684603 PMID:19684604 NCBI chr10:61,901,254...62,096,944
Ensembl chr10:61,901,684...62,096,944
JBrowse link
G ARNT aryl hydrocarbon receptor nuclear translocator EXP CTD Direct Evidence: marker/mechanism CTD PMID:22674224 NCBI chr 1:150,809,713...150,876,737
Ensembl chr 1:150,809,713...150,876,708
JBrowse link
G BAX BCL2 associated X, apoptosis regulator susceptibility IAGP
EXP
CTD Direct Evidence: marker/mechanism OMIM
CTD
NCBI chr19:48,954,825...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BCL2 BCL2 apoptosis regulator severity IEP mRNA:increased expression:bone marrow (human) RGD PMID:25982455 RGD:11076595 NCBI chr18:63,123,346...63,320,280
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BCL2L1 BCL2 like 1 treatment IDA
IEP
mRNA:increased expression:blood, mononuclear cell (human) RGD PMID:12469194, PMID:19020783 RGD:11353852, RGD:11353866 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989
JBrowse link
G BCR BCR activator of RhoGEF and GTPase susceptibility IAGP
EXP
CTD Direct Evidence: marker/mechanism OMIM
CTD
NCBI chr22:23,180,509...23,318,037
Ensembl chr22:23,179,704...23,318,037
JBrowse link
G CASP8 caspase 8 EXP CTD Direct Evidence: therapeutic CTD PMID:22010212 NCBI chr 2:201,233,443...201,287,711
Ensembl chr 2:201,233,443...201,287,711
JBrowse link
G CAST calpastatin IEP protein:increased expresssion:B cell RGD PMID:11264179 RGD:5509822 NCBI chr 5:96,662,037...96,774,683
Ensembl chr 5:96,525,267...96,779,595
JBrowse link
G CCND1 cyclin D1 IEP mRNA:increased expression:bone marrow (human) RGD PMID:22391157 RGD:11352824 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
JBrowse link
G CD40LG CD40 ligand ISO RGD PMID:9292526 RGD:11352271 NCBI chr  X:136,648,158...136,660,390
Ensembl chr  X:136,648,158...136,660,390
Ensembl chr  X:136,648,158...136,660,390
JBrowse link
G CD46 CD46 molecule IEP protein:increased expression:peripheral blood mononuclear cell (human) RGD PMID:16353080 RGD:11352810 NCBI chr 1:207,752,038...207,795,516
Ensembl chr 1:207,752,057...207,795,513
Ensembl chr 1:207,752,057...207,795,513
JBrowse link
G CD79B CD79b molecule IEP protein:decreased expression:bone marrow, mononuclear cell (human) RGD PMID:21487112 RGD:11250414 NCBI chr17:63,928,740...63,932,331
Ensembl chr17:63,928,740...63,932,354
Ensembl chr17:63,928,740...63,932,354
JBrowse link
G CD86 CD86 molecule severity IEP protein:increased expression:peripheral blood, bone marrow, mononuclear cell (human) RGD PMID:24283754 RGD:11354967 NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139
JBrowse link
G CDK6 cyclin dependent kinase 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24736461 NCBI chr 7:92,604,921...92,836,573
Ensembl chr 7:92,604,921...92,836,594
Ensembl chr 7:92,604,921...92,836,594
JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A disease_progression
susceptibility
no_association
IAGP
EXP
IEP
DNA:deletion: :
CTD Direct Evidence: marker/mechanism
DNA:missense mutations:cds:
CTD PMID:20453839, PMID:10090949, PMID:26104880, PMID:25675863, PMID:9204978 RGD:11251764, RGD:11057958, RGD:11252082, RGD:11252081 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,753...21,995,301
Ensembl chr 9:21,967,753...21,995,301
JBrowse link
G CEBPE CCAAT enhancer binding protein epsilon EXP CTD Direct Evidence: marker/mechanism CTD PMID:19684604 NCBI chr14:23,117,306...23,119,255
Ensembl chr14:23,117,304...23,119,616
Ensembl chr14:23,117,304...23,119,616
JBrowse link
G CFB complement factor B IAGP DNA:missense mutation:p.R32Q b(human) RGD PMID:6958349 RGD:11041155 NCBI chr 6:31,946,095...31,952,084
Ensembl chr 6:31,945,650...31,952,084
JBrowse link
G CREBBP CREB binding protein disease_progression IAGP DNA:mutations:multiple RGD PMID:25917266 RGD:11060149 NCBI chr16:3,725,054...3,880,727
Ensembl chr16:3,725,054...3,880,713
Ensembl chr16:3,725,054...3,880,713
JBrowse link
G CRLF2 cytokine receptor like factor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19838194 NCBI chr  Y:1,190,437...1,212,762
NCBI chr  X:1,190,437...1,212,762
Ensembl chr  X:1,187,549...1,212,723
JBrowse link
G CSF3 colony stimulating factor 3 treatment IDA RGD PMID:9250830 RGD:11039038 NCBI chr17:40,015,440...40,017,813
Ensembl chr17:40,015,361...40,017,813
JBrowse link
G CSPG4 chondroitin sulfate proteoglycan 4 severity IEP RGD PMID:8562939 RGD:734840 NCBI chr15:75,674,322...75,712,848
Ensembl chr15:75,674,322...75,712,848
JBrowse link
G CYBA cytochrome b-245 alpha chain IEP mRNA:increased expression:peripheral blood mononuclear cell: RGD PMID:19222940 RGD:11040545 NCBI chr16:88,643,289...88,651,079
Ensembl chr16:88,643,289...88,651,054
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 susceptibility
no_association
IAGP DNA:polymorphism:3"UTR:rs4646903(human)
DNA:polymorphism:3'UTR:3801T>C(human)
DNA:polymorphism:cds:2452C>A(p.T461N)(human)
RGD PMID:22964275, PMID:16676594, PMID:23725389 RGD:11352714, RGD:11352728, RGD:11352725 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22674224 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607
JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22674224 NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902
JBrowse link
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22674224 NCBI chr10:95,036,772...95,069,497
Ensembl chr10:95,036,772...95,069,497
JBrowse link
G CYP2D6 cytochrome P450 family 2 subfamily D member 6 susceptibility IAGP DNA:polymorphisms: :
DNA:SNP,deletion:splice junction,exon:1934G>A(human)
RGD PMID:11037802, PMID:19593802 RGD:11352820, RGD:11252111 NCBI chr22:42,126,499...42,130,810
Ensembl chr22:42,126,499...42,130,881
Ensembl chr22:42,126,499...42,130,881
JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:11774269 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220
JBrowse link
G CYP3A5 cytochrome P450 family 3 subfamily A member 5 disease_progression
susceptibility
IEP
IAGP
DNA:polymorphism: : RGD PMID:19650988, PMID:22215203 RGD:11353796, RGD:11353805 NCBI chr 7:99,648,194...99,679,996
Ensembl chr 7:99,648,194...99,679,998
JBrowse link
G DHFR dihydrofolate reductase disease_progression IAGP
IEP
DNA:polymorphisms, haplotype:promoter:
DNA:polymorphisms: :-317A>G, 829C>T (human)
RGD PMID:19861437, PMID:12972803, PMID:22969948, PMID:9226157 RGD:11039542, RGD:11039545, RGD:11039544, RGD:11039543 NCBI chr 5:80,626,226...80,654,983
Ensembl chr 5:80,626,226...80,654,983
JBrowse link
G DNMT3A DNA methyltransferase 3 alpha treatment IAGP DNA:mutations:exon, intron:p.R882(human) RGD PMID:25242092 RGD:11041125 NCBI chr 2:25,227,874...25,342,590
Ensembl chr 2:25,227,855...25,342,590
JBrowse link
G DNTT DNA nucleotidylexotransferase IEP protein:increased activity:peripheral blood,bone marrow: RGD PMID:7020399 RGD:8694149 NCBI chr10:96,304,434...96,338,564
Ensembl chr10:96,304,409...96,338,564
JBrowse link
G DPYD dihydropyrimidine dehydrogenase no_association
disease_progression
IAGP DNA:SNP: :85T>C (human)
DNA:SNPs: :2194G>A, 1156G>T (human)
DNA:splice-site mutation:intron:IVS14+1G>A (human)
RGD PMID:26846104, PMID:26846104, PMID:26846104 RGD:11098453, RGD:11098453, RGD:11098453 NCBI chr 1:97,077,743...97,921,059
Ensembl chr 1:97,077,743...97,995,000
JBrowse link
G DUX4 double homeobox 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27776115 NCBI chr 4:190,173,774...190,185,911
Ensembl chr 4:190,173,774...190,185,942
JBrowse link
G ENG endoglin disease_progression IEP RGD PMID:17572488 RGD:11041565 NCBI chr 9:127,815,012...127,854,773
Ensembl chr 9:127,815,013...127,854,658
Ensembl chr 9:127,815,013...127,854,658
JBrowse link
G EPHX1 epoxide hydrolase 1 susceptibility
no_association
IAGP
EXP
DNA:missense mutation, haplotype:exon:p.Y113H (human)
CTD Direct Evidence: marker/mechanism
DNA:SNPs:exon:rs1051740, rs2234922 (human)
DNA:polymorphisms:exon
DNA:missense mutation, haplotype:exon:p.H139R (human)
CTD PMID:21983886, PMID:21983886, PMID:22200898, PMID:22930568, PMID:19593802, PMID:21983886 RGD:11252110, RGD:11252114, RGD:11252113, RGD:11252111, RGD:11252110 NCBI chr 1:225,810,124...225,845,563
Ensembl chr 1:225,810,092...225,845,563
Ensembl chr 1:225,810,092...225,845,563
JBrowse link
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit susceptibility IAGP DNA:SNPs: :8092C>A, 19007G>A (human)
DNA:SNPs, haplotypes: :p.R194W, p.R280H, p.R399Q (human)
RGD PMID:16723154, PMID:16435384 RGD:11252160, RGD:11340204 NCBI chr19:45,407,334...45,451,547
Ensembl chr19:45,407,333...45,478,828
Ensembl chr19:45,407,333...45,478,828
JBrowse link
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit no_association IAGP DNA:missense mutations: :p.D312N, p.K751Q (human)
DNA:haplotype
RGD PMID:19101034, PMID:21987080 RGD:11252192, RGD:11340201 NCBI chr19:45,349,837...45,370,647
Ensembl chr19:45,349,837...45,370,918
JBrowse link
G ERG ETS transcription factor ERG EXP CTD Direct Evidence: marker/mechanism CTD PMID:27776115 NCBI chr21:38,367,261...38,661,783
Ensembl chr21:38,380,027...38,661,780
JBrowse link
G ETV6 ETS variant transcription factor 6 IAGP
EXP
ClinVar Annotator: match by term: Acute lymphoid leukemia
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
PMID:17255265 NCBI chr12:11,649,601...11,895,386
Ensembl chr12:11,649,674...11,895,377
Ensembl chr12:11,649,674...11,895,377
JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit ISS OMIM:247640 | OMIM:613065 | OMIM:613067 | OMIM:615545 MouseDO NCBI chr 7:148,807,374...148,884,344
Ensembl chr 7:148,807,383...148,884,321
Ensembl chr 7:148,807,383...148,884,321
JBrowse link
G F3 coagulation factor III, tissue factor IEP RGD PMID:8429686 RGD:11340211 NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759
JBrowse link
G FAS Fas cell surface death receptor disease_progression IEP protein:increased expression:CD34+ bone marrow cell RGD PMID:10500800, PMID:9711907 RGD:11049148, RGD:11049157 NCBI chr10:88,968,429...89,017,059
Ensembl chr10:88,990,531...89,017,059
JBrowse link
G FGA fibrinogen alpha chain IEP protein:increased expression:serum (human) RGD PMID:25317080 RGD:11040558 NCBI chr 4:154,583,126...154,590,742
Ensembl chr 4:154,583,128...154,590,745
JBrowse link
G FLT3 fms related receptor tyrosine kinase 3 susceptibility IAGP
EXP
ClinVar Annotator: match by term: Acute lymphocytic leukemia
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
OMIM
PMID:11290608 PMID:11442493 PMID:14604974 PMID:14670924 PMID:15256420 PMID:16857985 PMID:17606455 PMID:17889720 PMID:19657110 PMID:20733134 PMID:22368270 PMID:22504183 PMID:22504184 PMID:23261068 PMID:23321257 PMID:23430109 PMID:23714533 PMID:23783394 PMID:24046014 PMID:25157968 NCBI chr13:28,003,274...28,100,587
Ensembl chr13:28,003,274...28,100,592
JBrowse link
G FPGS folylpolyglutamate synthase EXP CTD Direct Evidence: marker/mechanism CTD PMID:25013492 NCBI chr 9:127,802,858...127,814,520
Ensembl chr 9:127,794,597...127,814,327
JBrowse link
G GFI1B growth factor independent 1B transcriptional repressor IEP mRNA:increased expression:blood: RGD PMID:19360458 RGD:11040460 NCBI chr 9:132,945,531...132,991,697
Ensembl chr 9:132,944,000...132,991,687
JBrowse link
G GH1 growth hormone 1 treatment IDA RGD PMID:2494952 RGD:11352727 NCBI chr17:63,917,203...63,918,839
Ensembl chr17:63,917,200...63,918,839
JBrowse link
G GNB1 G protein subunit beta 1 susceptibility IAGP
EXP
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Acute lymphoid leukemia
OMIM
CTD
ClinVar
PMID:25485910 PMID:27108799 NCBI chr 1:1,785,286...1,891,087
Ensembl chr 1:1,785,285...1,891,117
JBrowse link
G GPI glucose-6-phosphate isomerase IEP RGD PMID:6589021 RGD:11051848 NCBI chr19:34,353,330...34,402,413
Ensembl chr19:34,359,480...34,402,413
JBrowse link
G GPX1 glutathione peroxidase 1 treatment IDA RGD PMID:17317918, PMID:24698347 RGD:11352774, RGD:11352812 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,176...49,358,358
Ensembl chr 3:49,357,176...49,358,358
JBrowse link
G GSR glutathione-disulfide reductase IEP RGD PMID:24191316 RGD:11059506 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
JBrowse link
G GSTM1 glutathione S-transferase mu 1 disease_progression
susceptibility
no_association
IAGP RGD PMID:10666194, PMID:14607752, PMID:12827651, PMID:15738600 RGD:10450829, RGD:10755410, RGD:10755409, RGD:10755321 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039
JBrowse link
G GSTP1 glutathione S-transferase pi 1 disease_progression
no_association
susceptibility
IAGP DNA:haplotype:cds:
DNA:polymorphism: :1578 a>G(human)
DNA:transition mutation:exon:
RGD PMID:10666194, PMID:23979883, PMID:15738600 RGD:10450829, RGD:10755417, RGD:10755321 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656
Ensembl chr11:67,583,742...67,586,656
JBrowse link
G GSTT1 glutathione S-transferase theta 1 disease_progression
susceptibility
IAGP RGD PMID:10666194, PMID:14607752 RGD:10450829, RGD:10755410
G H1-2 H1.2 linker histone, cluster member susceptibility IAGP DNA:SNP, haplotype:enhancer: (rs807212) (human) RGD PMID:19806355 RGD:10755490 NCBI chr 6:26,055,740...26,056,470
Ensembl chr 6:26,055,787...26,056,428
Ensembl chr 6:26,055,787...26,056,428
JBrowse link
G HCK HCK proto-oncogene, Src family tyrosine kinase EXP CTD Direct Evidence: marker/mechanism CTD PMID:17344919 NCBI chr20:32,052,242...32,101,856
Ensembl chr20:32,052,197...32,101,856
Ensembl chr20:32,052,197...32,101,856
JBrowse link
G HDAC1 histone deacetylase 1 disease_progression IEP mRNA:increased expression:bone marrow,blood: RGD PMID:23948281 RGD:9681454 NCBI chr 1:32,292,083...32,333,628
Ensembl chr 1:32,292,083...32,333,635
JBrowse link
G HDAC2 histone deacetylase 2 disease_progression IEP mRNA:increased expression:bone marrow,blood: RGD PMID:23948281 RGD:9681454 NCBI chr 6:113,933,028...113,971,148
Ensembl chr 6:113,933,028...114,011,308
JBrowse link
G HDAC4 histone deacetylase 4 treatment IEP RGD PMID:23948281 RGD:9681454 NCBI chr 2:239,048,168...239,401,649
Ensembl chr 2:239,048,168...239,401,654
JBrowse link
G HFE homeostatic iron regulator no_association IAGP DNA:missense mutation:cds:p.H63D (human)
DNA:missense mutation: :p.H63D (human)
DNA:missense mutation:cds:p.C282Y (human)
RGD PMID:10627122, PMID:17107905, PMID:10627122 RGD:10755557, RGD:10755558, RGD:10755557 NCBI chr 6:26,087,347...26,098,343
Ensembl chr 6:26,087,281...26,098,343
JBrowse link
G HK1 hexokinase 1 IDA protein:decreased activity:platelet RGD PMID:21921332 RGD:11353881 NCBI chr10:69,269,991...69,401,882
Ensembl chr10:69,269,984...69,401,884
JBrowse link
G HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 IAGP DNA:polymorphisms, haplotype:cds:HLA-DQA1*01 (human) RGD PMID:9744491 RGD:11041762 NCBI chr 6:32,637,406...32,654,846
Ensembl chr 6:32,628,179...32,647,062
JBrowse link
G HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 IAGP DNA:polymorphisms, haplotypes:cds:multiple
DNA:polymorphisms, haplotype:cds:HLA-DQB1*0501 (human)
RGD PMID:22434102, PMID:9744491 RGD:11041749, RGD:11041762 NCBI chr 6:32,659,467...32,666,657
Ensembl chr 6:32,659,467...32,668,383
JBrowse link
G HLF HLF transcription factor, PAR bZIP family member EXP CTD Direct Evidence: marker/mechanism CTD PMID:26214592 NCBI chr17:55,264,960...55,325,187
Ensembl chr17:55,264,960...55,325,187
JBrowse link
G HOXD4 homeobox D4 IAGP
EXP
ClinVar Annotator: match by term: Leukemia, acute lymphoblastic, susceptibility to
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
PMID:15776434 NCBI chr 2:176,150,394...176,156,078
Ensembl chr 2:176,151,550...176,153,226
JBrowse link
G IDH1 isocitrate dehydrogenase (NADP(+)) 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22674224 NCBI chr 2:208,236,227...208,255,071
Ensembl chr 2:208,236,229...208,266,074
Ensembl chr 2:208,236,229...208,266,074
JBrowse link
G IFNG interferon gamma susceptibility IAGP DNA:SNP: :rs2069727(human) RGD PMID:21067287 RGD:10755691 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G IKZF1 IKAROS family zinc finger 1 IAGP
EXP
ClinVar Annotator: match by term: LEUKEMIA, ACUTE LYMPHOCYTIC, SUSCEPTIBILITY TO, 2
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
PMID:19684604 NCBI chr 7:50,303,453...50,405,101
Ensembl chr 7:50,304,068...50,405,101
JBrowse link
G IKZF2 IKAROS family zinc finger 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23334668 NCBI chr 2:212,999,692...213,155,297
Ensembl chr 2:212,999,691...213,152,427
JBrowse link
G IKZF3 IKAROS family zinc finger 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23334668 NCBI chr17:39,757,715...39,864,312
Ensembl chr17:39,757,718...39,864,312
JBrowse link
G IL10 interleukin 10 treatment IEP protein:decreased expression:blood RGD PMID:21653647, PMID:15860861 RGD:11049158, RGD:11049169 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G IRF4 interferon regulatory factor 4 IAGP DNA:SNP:intron:rs12203592 (human) RGD PMID:19897031 RGD:11526162 NCBI chr 6:391,752...411,443
Ensembl chr 6:391,752...411,443
JBrowse link
G ITPA inosine triphosphatase treatment
no_association
IAGP DNA:SNPs:exon:94C>A, 138G>A (human)
DNA:SNP:intron
RGD PMID:22009189, PMID:22009189 RGD:10766474, RGD:10766474 NCBI chr20:3,208,676...3,227,449
Ensembl chr20:3,208,868...3,223,870
JBrowse link
G KDM2B lysine demethylase 2B IEP mRNA:increased expression:bone marrow (human) RGD PMID:21310926 RGD:9588255 NCBI chr12:121,402,288...121,582,268
Ensembl chr12:121,429,096...121,581,023
JBrowse link
G KDM3B lysine demethylase 3B IEP protein:increased expression:bone marrow, mononuclear cell (human) RGD PMID:22615488 RGD:9586728 NCBI chr 5:138,352,685...138,437,027
Ensembl chr 5:138,352,685...138,437,028
JBrowse link
G KDM6A lysine demethylase 6A severity IAGP DNA:mutations:cds:multiple (human) RGD PMID:22377896 RGD:9684944 NCBI chr  X:44,873,182...45,112,779
Ensembl chr  X:44,873,188...45,112,779
Ensembl chr  X:44,873,188...45,112,779
Ensembl chr  X:44,873,188...45,112,779
JBrowse link
G KMT2A lysine methyltransferase 2A EXP CTD Direct Evidence: marker/mechanism CTD PMID:24736461 PMID:25730765 NCBI chr11:118,436,492...118,526,832
Ensembl chr11:118,436,490...118,526,832
JBrowse link
G KRAS KRAS proto-oncogene, GTPase disease_progression IAGP RGD PMID:17910045, PMID:25917266 RGD:11060148, RGD:11060149 NCBI chr12:25,205,246...25,250,929
Ensembl chr12:25,205,246...25,250,936
JBrowse link
G LMO2 LIM domain only 2 ISS OMIM:247640 | OMIM:613065 | OMIM:613067 | OMIM:615545 MouseDO NCBI chr11:33,858,576...33,892,076
Ensembl chr11:33,858,576...33,892,076
JBrowse link
G MEFV MEFV innate immuity regulator, pyrin susceptibility IAGP DNA:polymorphisms:cds:p.E148Q,M680I(human) RGD PMID:22942567 RGD:11531121 NCBI chr16:3,242,027...3,256,776
Ensembl chr16:3,242,027...3,256,633
Ensembl chr16:3,242,027...3,256,633
JBrowse link
G MTHFR methylenetetrahydrofolate reductase disease_progression
treatment
IAGP
EXP
DNA:missense mutation:cds:677C>T (p.A222V) (rs1801133) (human)
CTD Direct Evidence: marker/mechanism
DNA:missense mutation:cds:677C>T (human)
CTD PMID:16706930, PMID:19923983, PMID:21644011 RGD:10449398, RGD:10449407 NCBI chr 1:11,785,723...11,806,103
Ensembl chr 1:11,785,723...11,806,455
Ensembl chr 1:11,785,723...11,806,455
JBrowse link
G MTR 5-methyltetrahydrofolate-homocysteine methyltransferase disease_progression
susceptibility
no_association
IAGP DNA:SNP::rs10925235(human)
DNA:polymorphism: :66A>G(human)
DNA:polymorphism: :2756A>G(human)
RGD PMID:26605150, PMID:21618417, PMID:15159311, PMID:22453148 RGD:11531136, RGD:11531141, RGD:11531140, RGD:11531137 NCBI chr 1:236,794,304...236,903,981
Ensembl chr 1:236,795,292...236,921,278
Ensembl chr 1:236,795,292...236,921,278
JBrowse link
G MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase susceptibility IAGP
EXP
DNA:haplotype:cds:
CTD Direct Evidence: marker/mechanism
DNA:SNP: :rs3776455(human)
CTD PMID:17136115, PMID:17136115, PMID:23940529 RGD:11531133, RGD:11531135 NCBI chr 5:7,851,186...7,901,124
Ensembl chr 5:7,851,186...7,906,025
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor disease_progression IEP RGD PMID:25784651 RGD:11532748 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
JBrowse link
G NAT2 N-acetyltransferase 2 susceptibility
no_association
IAGP
EXP
DNA:polymorphisms: :
CTD Direct Evidence: marker/mechanism
DNA:polymorphisms,haplotype: :
CTD PMID:22200898, PMID:25804798, PMID:22215203, PMID:21888617 RGD:11532767, RGD:11353805, RGD:11532769 NCBI chr 8:18,386,585...18,401,219
Ensembl chr 8:18,391,282...18,401,218
JBrowse link
G NBN nibrin susceptibility IAGP
EXP
ClinVar Annotator: match by term: Leukemia, acute lymphoblastic, susceptibility to
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Acute lymphoid leukemia
OMIM
ClinVar
CTD
PMID:11325820 PMID:14559852 PMID:15338273 PMID:16474176 PMID:16810201 PMID:17695489 PMID:17894553 PMID:17899368 PMID:18049891 PMID:18280732 PMID:19393249 PMID:19452044 PMID:19523210 PMID:19813148 PMID:19908051 PMID:21212067 PMID:21698754 PMID:22131123 PMID:22373003 PMID:23317186 PMID:23555315 PMID:24093751 PMID:24113799 PMID:24549055 PMID:24728327 PMID:24830725 PMID:25619955 PMID:25712764 PMID:25741868 PMID:26083025 PMID:26315354 PMID:26467025 PMID:26722329 PMID:27153395 PMID:27616075 PMID:27621404 PMID:28076423 PMID:28261280 PMID:28376765 PMID:28492532 PMID:28591191 PMID:29335925 PMID:29678143 PMID:29785153 PMID:30287823 PMID:30441849 PMID:30590007 PMID:30651582 PMID:31159747 PMID:32566746 NCBI chr 8:89,933,331...89,984,698
Ensembl chr 8:89,933,336...90,003,228
Ensembl chr 8:89,933,336...90,003,228
JBrowse link
G NOS3 nitric oxide synthase 3 susceptibility
disease_progression
IAGP DNA:SNP: :rs3918186(human)
DNA:polymorphism, haplotype:cds,intron:P.E298D,-786T>C(human)
RGD PMID:23922896, PMID:20510681 RGD:11533639, RGD:11533646 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588
JBrowse link
G NOTCH3 notch receptor 3 ISS OMIM:247640 | OMIM:613065 | OMIM:613067 | OMIM:615545 MouseDO NCBI chr19:15,159,038...15,200,995
Ensembl chr19:15,159,038...15,200,995
JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 IAGP
EXP
DNA:mutation: :609C>T (human)
CTD Direct Evidence: marker/mechanism
DNA:missense mutations: :p.R139W (465C>T), p.P187S (609C>T) (human)
CTD PMID:11774269 PMID:17332311, PMID:18444911, PMID:11774269 RGD:10769347, RGD:10769359 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668
JBrowse link
G NRAS NRAS proto-oncogene, GTPase disease_progression IAGP DNA:missense mutation:cds: RGD PMID:25204082 RGD:11535045 NCBI chr 1:114,704,469...114,716,771
Ensembl chr 1:114,704,469...114,716,771
JBrowse link
G NSD2 nuclear receptor binding SET domain protein 2 EXP CTD Direct Evidence: therapeutic CTD PMID:24076604 NCBI chr 4:1,871,393...1,982,207
Ensembl chr 4:1,871,393...1,982,207
JBrowse link
G NT5C2 5'-nucleotidase, cytosolic II EXP CTD Direct Evidence: marker/mechanism CTD PMID:23377183 NCBI chr10:103,088,017...103,193,301
Ensembl chr10:103,087,185...103,277,605
Ensembl chr10:103,087,185...103,277,605
JBrowse link
G NUP214 nucleoporin 214 susceptibility IAGP
EXP
CTD Direct Evidence: marker/mechanism OMIM
CTD
NCBI chr 9:131,125,586...131,234,663
Ensembl chr 9:131,125,586...131,234,663
JBrowse link
G P2RY8 P2Y receptor family member 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19838194 NCBI chr  X:1,462,576...1,537,488
NCBI chr  Y:1,462,576...1,537,488
Ensembl chr  X:1,462,581...1,537,185
JBrowse link
G PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23334668 NCBI chr 8:80,967,810...81,112,068
Ensembl chr 8:80,967,810...81,112,068
JBrowse link
G PAX5 paired box 5 susceptibility IAGP
EXP
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Leukemia, acute lymphoblastic, susceptibility to, 3
ClinVar Annotator: match by term: Acute lymphoid leukemia
OMIM
CTD
ClinVar
PMID:24013638 PMID:25741868 PMID:26214592 NCBI chr 9:36,833,269...37,034,268
Ensembl chr 9:36,833,269...37,034,268
JBrowse link
G PON1 paraoxonase 1 susceptibility IAGP DNA:missense mutations:cds:p.L55M (rs854560), p.Q192R (rs662) (human) RGD PMID:22976839 RGD:11552580 NCBI chr 7:95,297,676...95,324,532
Ensembl chr 7:95,297,676...95,324,532
JBrowse link
G PRAME PRAME nuclear receptor transcriptional regulator severity IEP mRNA:increased expression:blood (human) RGD PMID:27275197 RGD:11535025 NCBI chr22:22,547,701...22,559,294
Ensembl chr22:22,547,701...22,559,361
JBrowse link
G PRDM14 PR/SET domain 14 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19043588 NCBI chr 8:70,051,613...70,071,252
Ensembl chr 8:70,051,651...70,071,693
JBrowse link
G PTEN phosphatase and tensin homolog ISS OMIM:247640 | OMIM:613065 | OMIM:613067 | OMIM:615545 MouseDO NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,863,625...87,971,930
JBrowse link
G RB1 RB transcriptional corepressor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23334668 NCBI chr13:48,303,751...48,481,890
Ensembl chr13:48,303,744...48,599,436
Ensembl chr13:48,303,744...48,599,436
JBrowse link
G RUNX1 RUNX family transcription factor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17255265 NCBI chr21:34,787,801...35,049,334
Ensembl chr21:34,787,801...36,004,667
JBrowse link
G SLC19A1 solute carrier family 19 member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17255265 NCBI chr21:45,502,517...45,563,140
Ensembl chr21:45,493,572...45,573,365
JBrowse link
G SNRPE small nuclear ribonucleoprotein polypeptide E severity IEP mRNA:decreased expression:bone marrow, blood, mononuclear cell (human) RGD PMID:23915977 RGD:10768836 NCBI chr 1:203,861,599...203,871,152
Ensembl chr 1:203,861,599...203,871,152
JBrowse link
G TAL1 TAL bHLH transcription factor 1, erythroid differentiation factor susceptibility IAGP
EXP
CTD Direct Evidence: marker/mechanism OMIM
CTD
NCBI chr 1:47,216,290...47,232,389
Ensembl chr 1:47,216,290...47,232,220
JBrowse link
G TAL2 TAL bHLH transcription factor 2 susceptibility IAGP
EXP
CTD Direct Evidence: marker/mechanism OMIM
CTD
NCBI chr 9:105,662,457...105,663,124
Ensembl chr 9:105,662,457...105,663,124
JBrowse link
G TCF3 transcription factor 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26214592 NCBI chr19:1,609,292...1,652,615
Ensembl chr19:1,609,290...1,652,615
JBrowse link
G TCN2 transcobalamin 2 IEP protein:altered activity:plasma: RGD PMID:8754152 RGD:11059889 NCBI chr22:30,607,174...30,627,271
Ensembl chr22:30,607,003...30,627,271
JBrowse link
G TERT telomerase reverse transcriptase IAGP
IEP
DNA:SNPs:promoter, introns:g.1296486C>T, g.12866516A>C, g.1279790G>A (rs2735940, rs2736100, rs10069690) (human) RGD PMID:23066086, PMID:15621763 RGD:11038654, RGD:11038667 NCBI chr 5:1,253,167...1,295,068
Ensembl chr 5:1,253,147...1,295,068
Ensembl chr 5:1,253,147...1,295,068
JBrowse link
G TM9SF2 transmembrane 9 superfamily member 2 IEP mRNA:increased expression:bone marrow, mononuclear cells (human) RGD PMID:12730115 RGD:2317244 NCBI chr13:99,501,472...99,564,048
Ensembl chr13:99,446,311...99,564,048
JBrowse link
G TP53 tumor protein p53 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23334668 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
Ensembl chr17:7,661,779...7,687,538
JBrowse link
G TPMT thiopurine S-methyltransferase treatment
no_association
IAGP DNA:SNPs:multiple
DNA:SNPs:introns:12356C>T, 16638C>T, 26354G>T (rs4449636, rs2518463, rs2842949) (human)
DNA:SNPs:exon:374C>T, 719A>G (rs2842934, rs1142345) (human)
DNA:SNPs: :multiple
RGD PMID:17164697, PMID:22009189, PMID:22009189, PMID:24499706 RGD:11038720, RGD:10766474, RGD:10766474, RGD:11038723 NCBI chr 6:18,128,311...18,155,169
Ensembl chr 6:18,128,311...18,155,077
JBrowse link
G TYMS thymidylate synthetase treatment IAGP DNA:repeats: : rs347430033(human) RGD PMID:25007187 RGD:11080979 NCBI chr18:657,653...673,578
Ensembl chr18:657,653...673,578
JBrowse link
G VPREB1 V-set pre-B cell surrogate light chain 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26214592 NCBI chr22:22,244,786...22,245,515
Ensembl chr22:22,244,780...22,245,515
JBrowse link
G XRCC1 X-ray repair cross complementing 1 susceptibility
no_association
IAGP
EXP
DNA:missense mutation, haplotype: :p.R399Q (human)
CTD Direct Evidence: marker/mechanism
DNA:missense mutation: :p.R399Q (human)
DNA:missense mutation: :p.R194W (human)
CTD PMID:21983886, PMID:21983886, PMID:19101034, PMID:19101034 RGD:11252110, RGD:11252192, RGD:11252192 NCBI chr19:43,543,311...43,575,527
Ensembl chr19:43,543,040...43,580,473
Ensembl chr19:43,543,040...43,580,473
JBrowse link
Acute Lymphoblastic Leukemia, with Lymphomatous Features term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase IAGP ClinVar Annotator: match by term: Lymphoblastic leukemia, acute, with lymphomatous features ClinVar PMID:10988075 PMID:11423618 PMID:11853795 PMID:11861307 PMID:11964322 PMID:12130516 PMID:12399961 PMID:12623848 PMID:14559829 PMID:14745431 PMID:15194504 PMID:15256422 PMID:15381060 PMID:18615627 PMID:19466505 PMID:19652056 PMID:20367437 PMID:20512393 PMID:20537386 PMID:20697894 PMID:20963643 PMID:21505103 PMID:21562040 PMID:21762985 PMID:21872826 PMID:21895409 PMID:22306673 PMID:22772060 PMID:22870928 PMID:23355941 PMID:23540562 PMID:23676790 PMID:24236021 PMID:24456693 PMID:25157968 PMID:25686603 NCBI chr 9:130,713,043...130,887,675
Ensembl chr 9:130,713,016...130,887,675
JBrowse link
G CRLF2 cytokine receptor like factor 2 IAGP ClinVar Annotator: match by term: Lymphoblastic leukemia, acute, with lymphomatous features ClinVar PMID:19907440 PMID:19965641 PMID:20018760 PMID:22368272 NCBI chr  Y:1,190,437...1,212,762
NCBI chr  X:1,190,437...1,212,762
Ensembl chr  X:1,187,549...1,212,723
JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 susceptibility IAGP DNA:polymorphism:G15631T RGD PMID:19144407 RGD:6480472 NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398
JBrowse link
G FGFR1 fibroblast growth factor receptor 1 IAGP ClinVar Annotator: match by term: Lymphoblastic leukemia, acute, with lymphomatous features ClinVar PMID:25705862 PMID:26619011 PMID:26942290 NCBI chr 8:38,411,143...38,468,635
Ensembl chr 8:38,400,215...38,468,834
JBrowse link
G IL7R interleukin 7 receptor IAGP ClinVar Annotator: match by term: Lymphoblastic leukemia, acute, with lymphomatous features ClinVar PMID:22897847 PMID:22955920 NCBI chr 5:35,856,891...35,879,603
Ensembl chr 5:35,852,695...35,879,603
JBrowse link
G INSL6 insulin like 6 IAGP ClinVar Annotator: match by term: Lymphoblastic leukemia, acute, with lymphomatous features ClinVar PMID:18805579 PMID:19470474 PMID:20585391 PMID:22368270 PMID:22955920 NCBI chr 9:4,992,409...5,185,707
Ensembl chr 9:5,123,880...5,185,647
JBrowse link
G JAK1 Janus kinase 1 IAGP ClinVar Annotator: match by term: Lymphoblastic leukemia, acute, with lymphomatous features ClinVar PMID:16239216 PMID:19139102 PMID:19470474 PMID:19838194 PMID:20167706 PMID:21436584 PMID:21680795 PMID:22955920 PMID:25356970 PMID:28111307 NCBI chr 1:64,833,229...65,067,746
Ensembl chr 1:64,833,229...65,067,754
JBrowse link
G JAK2 Janus kinase 2 IAGP ClinVar Annotator: match by term: Lymphoblastic leukemia, acute, with lymphomatous features ClinVar PMID:18805579 PMID:19470474 PMID:20585391 PMID:22368270 PMID:22955920 NCBI chr 9:4,984,390...5,129,948
Ensembl chr 9:4,984,390...5,128,183
Ensembl chr 9:4,984,390...5,128,183
JBrowse link
G JAK3 Janus kinase 3 IAGP ClinVar Annotator: match by term: Lymphoblastic leukemia, acute, with lymphomatous features ClinVar PMID:10982185 PMID:16843266 PMID:18270328 PMID:20132407 PMID:20372971 PMID:21599579 PMID:21821710 PMID:24728327 PMID:25157968 PMID:28492532 NCBI chr19:17,824,782...17,848,071
Ensembl chr19:17,824,780...17,848,071
JBrowse link
acute megakaryocytic leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCG2 ATP binding cassette subfamily G member 2 (Junior blood group) IEP RGD PMID:21640380 RGD:11081147 NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628
JBrowse link
G APC APC regulator of WNT signaling pathway IAGP ClinVar Annotator: match by term: Acute megakaryoblastic leukemia ClinVar PMID:25741868 PMID:28492532 NCBI chr 5:112,707,498...112,846,239
Ensembl chr 5:112,707,498...112,846,239
JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 EXP CTD Direct Evidence: therapeutic CTD PMID:16166298 NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636
JBrowse link
G CORO7 coronin 7 IAGP ClinVar Annotator: match by term: Acute megakaryoblastic leukemia ClinVar NCBI chr16:4,354,542...4,416,596
Ensembl chr16:4,354,542...4,425,705
JBrowse link
G CORO7-PAM16 CORO7-PAM16 readthrough IAGP ClinVar Annotator: match by term: Acute megakaryoblastic leukemia ClinVar NCBI chr16:4,340,251...4,416,596
Ensembl chr16:4,340,251...4,420,494
JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit IAGP associated with Down Syndrome;DNA:mutations:multiple (human) RGD PMID:24056718 RGD:10450890 NCBI chr 7:148,807,374...148,884,344
Ensembl chr 7:148,807,383...148,884,321
Ensembl chr 7:148,807,383...148,884,321
JBrowse link
G GATA1 GATA binding protein 1 IAGP ClinVar Annotator: match by term: Acute megakaryoblastic leukemia ClinVar PMID:15070711 NCBI chr  X:48,786,590...48,794,311
Ensembl chr  X:48,786,562...48,794,311
Ensembl chr  X:48,786,562...48,794,311
JBrowse link
G GFI1B growth factor independent 1B transcriptional repressor IEP mRNA:increased expression:bone marrow cell: RGD PMID:17156408 RGD:11040507 NCBI chr 9:132,945,531...132,991,697
Ensembl chr 9:132,944,000...132,991,687
JBrowse link
G JAK3 Janus kinase 3 IMP
IAGP
ClinVar Annotator: match by term: Acute megakaryoblastic leukemia ClinVar PMID:10982185 PMID:16843266 PMID:18270328 PMID:18397343 PMID:20132407 PMID:20372971 PMID:20385788 PMID:20400977 PMID:21599579 PMID:21821710 PMID:22271575 PMID:24728327 PMID:25157968 PMID:28492532, PMID:16843266 RGD:11531113 NCBI chr19:17,824,782...17,848,071
Ensembl chr19:17,824,780...17,848,071
JBrowse link
G MDGA1 MAM domain containing glycosylphosphatidylinositol anchor 1 IAGP ClinVar Annotator: match by term: Acute megakaryoblastic leukemia ClinVar NCBI chr 6:37,630,679...37,697,883
Ensembl chr 6:37,630,679...37,699,306
JBrowse link
G MRTFA myocardin related transcription factor A IAGP RGD PMID:11431691 RGD:1599948 NCBI chr22:40,410,289...40,636,719
Ensembl chr22:40,410,281...40,636,719
JBrowse link
G MT-ND6 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 IAGP ClinVar Annotator: match by term: Acute megakaryoblastic leukemia ClinVar NCBI chr MT:14,149...14,673
Ensembl chr MT:14,149...14,673
JBrowse link
G PCF11 PCF11 cleavage and polyadenylation factor subunit IAGP ClinVar Annotator: match by term: Acute megakaryoblastic leukemia ClinVar NCBI chr11:83,157,095...83,187,451
Ensembl chr11:83,156,988...83,187,451
JBrowse link
G PRAME PRAME nuclear receptor transcriptional regulator IEP associated with Down Syndrome;mRNA:increased expression:mononuclear cell (human) RGD PMID:15180862 RGD:11535064 NCBI chr22:22,547,701...22,559,294
Ensembl chr22:22,547,701...22,559,361
JBrowse link
G PTEN phosphatase and tensin homolog IAGP ClinVar Annotator: match by term: Acute megakaryoblastic leukemia ClinVar PMID:10848731 PMID:17941496 PMID:20600018 PMID:21194675 PMID:21343951 PMID:21659347 PMID:22281088 PMID:22520842 PMID:23335809 PMID:23475934 PMID:23886400 PMID:24778394 PMID:26376867 PMID:28492532 PMID:29663862 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,863,625...87,971,930
JBrowse link
G RASAL3 RAS protein activator like 3 IAGP ClinVar Annotator: match by term: Acute megakaryoblastic leukemia ClinVar NCBI chr19:15,451,624...15,464,571
Ensembl chr19:15,451,624...15,464,544
JBrowse link
G RUNX1 RUNX family transcription factor 1 onset ISO RGD PMID:15856017 RGD:11251701 NCBI chr21:35,372,507...35,580,764
Ensembl chr21:34,787,801...36,004,667
JBrowse link
G RUNX1 RUNX family transcription factor 1 onset ISO RGD PMID:15856017 RGD:11251701 NCBI chr21:34,787,801...35,049,334
Ensembl chr21:34,787,801...36,004,667
JBrowse link
G SLC9A2 solute carrier family 9 member A2 IAGP ClinVar Annotator: match by term: Acute megakaryoblastic leukemia ClinVar NCBI chr 2:102,619,553...102,711,355
Ensembl chr 2:102,619,553...102,711,355
JBrowse link
G SNCB synuclein beta IEP RGD PMID:21264917 RGD:6478703 NCBI chr 5:176,620,082...176,630,556
Ensembl chr 5:176,620,082...176,630,556
JBrowse link
G TP53 tumor protein p53 IAGP ClinVar Annotator: match by term: Acute megakaryoblastic leukemia ClinVar NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
Ensembl chr17:7,661,779...7,687,538
JBrowse link
acute monocytic leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNMT3A DNA methyltransferase 3 alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:21399634 NCBI chr 2:25,227,874...25,342,590
Ensembl chr 2:25,227,855...25,342,590
JBrowse link
G KMT2A lysine methyltransferase 2A EXP CTD Direct Evidence: marker/mechanism CTD PMID:8282816 NCBI chr11:118,436,492...118,526,832
Ensembl chr11:118,436,490...118,526,832
JBrowse link
G MLLT10 MLLT10 histone lysine methyltransferase DOT1L cofactor IAGP RGD PMID:7662954 RGD:1598771 NCBI chr10:21,524,616...21,743,630
Ensembl chr10:21,524,646...21,743,630
JBrowse link
G NF1 neurofibromin 1 IAGP ClinVar Annotator: match by term: Acute monocytic leukemia ClinVar PMID:23407919 PMID:25741868 PMID:28492532 NCBI chr17:31,094,927...31,377,677
Ensembl chr17:31,094,927...31,382,116
JBrowse link
G STK11 serine/threonine kinase 11 IAGP ClinVar Annotator: match by term: Acute monocytic leukemia ClinVar PMID:25117502 PMID:25741868 PMID:25980754 PMID:26467025 PMID:28492532 NCBI chr19:1,205,778...1,228,431
Ensembl chr19:1,177,558...1,228,431
Ensembl chr19:1,177,558...1,228,431
JBrowse link
acute myeloid leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC3 ATP binding cassette subfamily C member 3 disease_progression IEP RGD PMID:26512967 RGD:11081145 NCBI chr17:50,634,881...50,692,253
Ensembl chr17:50,634,777...50,692,253
JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 (Junior blood group) disease_progression
treatment
IEP RGD PMID:26512967, PMID:12145683 RGD:11081145, RGD:11099971 NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628
JBrowse link
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase IAGP DNA:translocation: : RGD PMID:12161353 RGD:10450603 NCBI chr 9:130,713,043...130,887,675
Ensembl chr 9:130,713,016...130,887,675
JBrowse link
G ACSL6 acyl-CoA synthetase long chain family member 6 IAGP DNA:translocation: :t(5;12)(q31;p13) (human) RGD PMID:10502316 RGD:1599805 NCBI chr 5:131,949,973...132,012,068
Ensembl chr 5:131,949,973...132,012,243
JBrowse link
G ADCY7 adenylate cyclase 7 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18206229 NCBI chr16:50,246,138...50,318,135
Ensembl chr16:50,246,137...50,318,135
JBrowse link
G AGRN agrin EXP CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 1:1,020,102...1,056,119
Ensembl chr 1:1,020,120...1,056,118
JBrowse link
G ALK ALK receptor tyrosine kinase IAGP ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:25741868 PMID:28492532 NCBI chr 2:29,190,992...29,921,589
Ensembl chr 2:29,192,774...29,921,586
JBrowse link
G ANAPC2 anaphase promoting complex subunit 2 IEP mRNA:increased expression:blood (human) RGD PMID:26046517 RGD:11067888 NCBI chr 9:137,174,784...137,188,585
Ensembl chr 9:137,174,784...137,188,560
JBrowse link
G ANXA2 annexin A2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr15:60,347,151...60,398,025
Ensembl chr15:60,347,134...60,402,883
JBrowse link
G ANXA4 annexin A4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 2:69,643,808...69,827,112
Ensembl chr 2:69,644,425...69,827,112
JBrowse link
G ANXA5 annexin A5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 4:121,667,946...121,696,994
Ensembl chr 4:121,667,946...121,696,995
JBrowse link
G ANXA6 annexin A6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 5:151,100,706...151,157,779
Ensembl chr 5:151,100,706...151,157,785
JBrowse link
G AQP9 aquaporin 9 EXP CTD Direct Evidence: therapeutic CTD PMID:16968895 NCBI chr15:58,138,169...58,185,911
Ensembl chr15:58,138,169...58,185,911
JBrowse link
G ARID4A AT-rich interaction domain 4A ISS OMIM:601626 MouseDO NCBI chr14:58,298,385...58,373,876
Ensembl chr14:58,298,504...58,373,887
JBrowse link
G ASMTL acetylserotonin O-methyltransferase like EXP CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr  X:1,403,139...1,453,794
NCBI chr  Y:1,403,139...1,453,794
Ensembl chr  X:1,403,139...1,453,762
JBrowse link
G ASXL1 ASXL transcriptional regulator 1 disease_progression IAGP
ISS
DNA:mutations:exon:
OMIM:601626
MouseDO PMID:20693432 RGD:11038706 NCBI chr20:32,358,062...32,439,319
Ensembl chr20:32,358,330...32,439,319
JBrowse link
G ASXL2 ASXL transcriptional regulator 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27798625 NCBI chr 2:25,733,753...25,878,487
Ensembl chr 2:25,733,753...25,878,487
JBrowse link
G ATG2B autophagy related 2B IAGP ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar NCBI chr14:96,279,195...96,363,341
Ensembl chr14:96,279,195...96,363,341
JBrowse link
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 1:169,106,690...169,132,719
Ensembl chr 1:169,105,697...169,132,722
JBrowse link
G BAALC BAALC binder of MAP3K1 and KLF4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19822134 NCBI chr 8:103,140,725...103,230,305
Ensembl chr 8:103,140,713...103,230,305
JBrowse link
G BACH2 BTB domain and CNC homolog 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21441929 NCBI chr 6:89,926,528...90,296,843
Ensembl chr 6:89,926,528...90,296,908
JBrowse link
G BCL2 BCL2 apoptosis regulator susceptibility
severity
IAGP
EXP
IEP
DNA:snp:promoter:g.-938C>A (human)
CTD Direct Evidence: marker/mechanism
DNA:snp:exon:c.+21A>G (rs1801018) (human)
ratio with Flt3, Kit;mRNA:decreased expression:mononuclear cell (human)
CTD PMID:23906301, PMID:25957891, PMID:19520430, PMID:25216797 RGD:11526107, RGD:11526111, RGD:11526109 NCBI chr18:63,123,346...63,320,280
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BCL2L1 BCL2 like 1 severity IEP mRNA:increased expression:peripheral blood, bone marrow, blast cell (human) RGD PMID:11410409 RGD:11353851 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989
JBrowse link
G BDKRB1 bradykinin receptor B1 IAGP ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar NCBI chr14:96,256,210...96,264,763
Ensembl chr14:96,256,210...96,268,967
JBrowse link
G BDKRB2 bradykinin receptor B2 IAGP ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar NCBI chr14:96,204,839...96,244,164
Ensembl chr14:96,204,679...96,244,166
JBrowse link
G BMI1 BMI1 proto-oncogene, polycomb ring finger IDA RGD PMID:16105758 RGD:1580059 NCBI chr10:22,321,099...22,331,484
Ensembl chr10:22,321,099...22,331,484
JBrowse link
G BRCA2 BRCA2 DNA repair associated IAGP ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:15766593 PMID:25741868 PMID:26467025 PMID:28492532 PMID:29021639 NCBI chr13:32,315,508...32,400,268
Ensembl chr13:32,315,086...32,400,268
Ensembl chr13:32,315,086...32,400,268
JBrowse link
G BRD4 bromodomain containing 4 ISO RGD PMID:21814200 RGD:9586350 NCBI chr19:15,235,519...15,332,539
Ensembl chr19:15,235,519...15,332,545
JBrowse link
G BRD7 bromodomain containing 7 susceptibility IEP
IAGP
mRNA:increased expression:bone marrow:
DNA:haplotype:cds:737A>G,495C>T(human)
RGD PMID:18772500, PMID:18772500 RGD:9586443, RGD:9586443 NCBI chr16:50,315,957...50,368,988
Ensembl chr16:50,313,487...50,368,988
Ensembl chr16:50,313,487...50,368,988
JBrowse link
G BTG1 BTG anti-proliferation factor 1 disease_progression IEP RGD PMID:15449376 RGD:1549463 NCBI chr12:92,140,278...92,145,846
Ensembl chr12:92,140,278...92,145,846
JBrowse link
G C14orf132 chromosome 14 open reading frame 132 IAGP ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar NCBI chr14:96,039,362...96,093,971
Ensembl chr14:96,039,324...96,093,889
Ensembl chr14:96,039,324...96,093,889
JBrowse link
G CALR calreticulin IEP mRNA:increased expression:peripheral blood (human) RGD PMID:26640226 RGD:11076986 NCBI chr19:12,938,609...12,944,489
Ensembl chr19:12,938,578...12,944,489
JBrowse link
G CAPG capping actin protein, gelsolin like EXP CTD Direct Evidence: marker/mechanism CTD PMID:18206229 NCBI chr 2:85,394,753...85,418,467
Ensembl chr 2:85,394,753...85,418,432
JBrowse link
G CAPN2 calpain 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 1:223,701,597...223,776,018
Ensembl chr 1:223,701,593...223,776,018
JBrowse link
G CASP7 caspase 7 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr10:113,679,194...113,730,909
Ensembl chr10:113,679,162...113,730,907
JBrowse link
G CBFB core-binding factor subunit beta IAGP
EXP
ClinVar Annotator: match by term: Acute myeloid leukemia
CTD Direct Evidence: marker/mechanism
OMIM
ClinVar
CTD
PMID:18206229 PMID:25741868 PMID:27798625 NCBI chr16:67,029,149...67,101,058
Ensembl chr16:67,028,984...67,101,058
JBrowse link
G CBL Cbl proto-oncogene disease_progression IAGP associated with Myelodysplastic Syndromes;DNA:mutations:exons: RGD PMID:22131879 RGD:11038796 NCBI chr11:119,206,339...119,308,149
Ensembl chr11:119,206,298...119,313,926
Ensembl chr11:119,206,298...119,313,926
JBrowse link
G CCL2 C-C motif chemokine ligand 2 treatment ISO
IEP
protein:increased expression:plasma (human) RGD PMID:25382729, PMID:17822317 RGD:11528532, RGD:11528537 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,218...34,257,203
JBrowse link
G CCNA1 cyclin A1 IEP protein:increased expression:leukocyte (human) RGD PMID:10068680 RGD:2316304 NCBI chr13:36,430,488...36,442,870
Ensembl chr13:36,431,520...36,442,870
JBrowse link
G CCND1 cyclin D1 treatment IEP
IDA
mRNA:increased expression:bone marrow (human)
human tumor in a mouse model
RGD PMID:22391157, PMID:21928377 RGD:11352824, RGD:11353789 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
JBrowse link
G CCND2 cyclin D2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27798625 NCBI chr12:4,273,762...4,305,353
Ensembl chr12:4,269,771...4,305,353
Ensembl chr12:4,269,771...4,305,353
JBrowse link
G CD33 CD33 molecule EXP CTD Direct Evidence: marker/mechanism CTD PMID:12921496 NCBI chr19:51,211,054...51,240,016
Ensembl chr19:51,225,064...51,243,860
JBrowse link
G CD44 CD44 molecule (Indian blood group) EXP CTD Direct Evidence: marker/mechanism CTD PMID:23098472 NCBI chr11:35,139,168...35,232,402
Ensembl chr11:35,138,882...35,232,402
Ensembl chr11:35,138,882...35,232,402
JBrowse link
G CD86 CD86 molecule severity ISO
IEP
protein:increased expression:mononuclear cell of bone marrow (human) RGD PMID:19197726, PMID:16115907 RGD:4892295, RGD:11354960 NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139
JBrowse link
G CD9 CD9 molecule EXP CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr12:6,199,946...6,238,266
Ensembl chr12:6,199,715...6,238,271
JBrowse link
G CDH1 cadherin 1 disease_progression IAGP DNA:hypermethylation:promoter: RGD PMID:15863205 RGD:11252161 NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,541
Ensembl chr16:68,737,292...68,835,541
JBrowse link
G CDK6 cyclin dependent kinase 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18206229 NCBI chr 7:92,604,921...92,836,573
Ensembl chr 7:92,604,921...92,836,594
Ensembl chr 7:92,604,921...92,836,594
JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B IAGP DNA:deletion: : RGD PMID:9171997 RGD:10450601 NCBI chr12:12,717,368...12,722,369
Ensembl chr12:12,715,058...12,722,369
Ensembl chr12:12,715,058...12,722,369
JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A disease_progression IAGP
IEP
DNA:deletion: :
mRNA,protein:altered expression:bone marrow:
RGD PMID:11064355, PMID:11697625 RGD:11251749, RGD:11252080 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,753...21,995,301
Ensembl chr 9:21,967,753...21,995,301
JBrowse link
G CDKN2B cyclin dependent kinase inhibitor 2B susceptibility
treatment
disease_progression
IAGP
IEP
ISO
IDA
DNA:hypermethylation: :
mRNA:decreased expression:granulocyte,monocyte:
DNA:hypermethylation:promoter:
DNA:deletion: :
RGD PMID:25616284, PMID:9001419, PMID:14681685, PMID:27168825, PMID:15863205, PMID:11064355 RGD:11251739, RGD:11252196, RGD:11252167, RGD:11252164, RGD:11252161, RGD:11251749 NCBI chr 9:22,002,903...22,009,313
Ensembl chr 9:22,002,903...22,009,305
JBrowse link
G CEBPA CCAAT enhancer binding protein alpha IAGP
EXP
ClinVar Annotator: match by term: Acute myeloid leukemia
ClinVar Annotator: match by term: Acute myelogenous leukemia
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: AML - Acute myeloid leukemia
ClinVar Annotator: match by term: Leukemia, acute myelogenous
ClinVar
CTD
OMIM
PMID:11242107 PMID:12661007 PMID:12692518 PMID:14726504 PMID:15575056 PMID:18768433 PMID:18987666 PMID:19731081 PMID:19822134 PMID:23926458 PMID:24220272 PMID:24728327 PMID:25741868 PMID:26162409 PMID:26721895 PMID:27005833 PMID:28250006 PMID:28492532 PMID:29296967 PMID:30420649 NCBI chr19:33,299,934...33,302,564
Ensembl chr19:33,299,934...33,302,534
JBrowse link
G CEBPD CCAAT enhancer binding protein delta EXP CTD Direct Evidence: marker/mechanism CTD PMID:17234736 NCBI chr 8:47,736,913...47,738,164
Ensembl chr 8:47,736,913...47,738,164
JBrowse link
G CFHR1 complement factor H related 1 susceptibility IAGP DNA:deletion: : RGD PMID:26317246 RGD:11341662 NCBI chr 1:196,819,731...196,832,189
Ensembl chr 1:196,819,757...196,832,189
Ensembl chr 1:196,819,757...196,832,189
JBrowse link
G CFLAR CASP8 and FADD like apoptosis regulator disease_progression IEP RGD PMID:23167276 RGD:11341679 NCBI chr 2:201,116,164...201,176,687
Ensembl chr 2:201,116,154...201,176,687
JBrowse link
G CHI3L1 chitinase 3 like 1 severity IEP protein:increased secretion:serum (human) RGD PMID:16361549 RGD:4892644 NCBI chr 1:203,178,931...203,186,704
Ensembl chr 1:203,178,931...203,186,704
JBrowse link
G CHIC2 cysteine rich hydrophobic domain 2 IAGP OMIM NCBI chr 4:53,996,335...54,064,690
Ensembl chr 4:54,009,789...54,064,605
JBrowse link
G CHMP5 charged multivesicular body protein 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17708794 NCBI chr 9:33,265,049...33,282,070
Ensembl chr 9:33,264,879...33,282,070
JBrowse link
G CNR2 cannabinoid receptor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15039279 NCBI chr 1:23,870,515...23,913,362
Ensembl chr 1:23,870,515...23,913,362
JBrowse link
G CREBBP CREB binding protein IAGP
ISS
DNA:translocations:intron:IVS2 (human)
OMIM:601626
MouseDO PMID:12461753 RGD:734819 NCBI chr16:3,725,054...3,880,727
Ensembl chr16:3,725,054...3,880,713
Ensembl chr16:3,725,054...3,880,713
JBrowse link
G CSF1R colony stimulating factor 1 receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:1390197 NCBI chr 5:150,053,295...150,113,365
Ensembl chr 5:150,053,291...150,113,372
JBrowse link
G CSF2 colony stimulating factor 2 treatment IDA
EXP
CTD Direct Evidence: marker/mechanism CTD PMID:21441929, PMID:1826536 RGD:10449528 NCBI chr 5:132,073,789...132,076,170
Ensembl chr 5:132,073,789...132,076,170
JBrowse link
G CSF3 colony stimulating factor 3 treatment IDA
EXP
CTD Direct Evidence: therapeutic CTD PMID:7528855, PMID:10673519 RGD:11039033 NCBI chr17:40,015,440...40,017,813
Ensembl chr17:40,015,361...40,017,813
JBrowse link
G CSF3R colony stimulating factor 3 receptor disease_progression
susceptibility
IAGP
ISO
ClinVar Annotator: match by term: Acute myelocytic leukemia
associated with Severe Congenital Neutropenia;DNA:nonsense mutation:cds:
ClinVar PMID:23604229 PMID:23634996 PMID:23656643 PMID:24081659 PMID:24403076 PMID:24614839 PMID:24854193 PMID:25491280 PMID:25741868 PMID:25932451 PMID:26875968 PMID:27148573 PMID:27581359 PMID:28209919 PMID:28219221 PMID:28492532 PMID:28762112 PMID:30967555, PMID:24746896, PMID:9001427, PMID:21911095 RGD:10450468, RGD:10450487, RGD:10450470 NCBI chr 1:36,466,043...36,483,314
Ensembl chr 1:36,466,043...36,483,278
JBrowse link
G CST3 cystatin C EXP CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr20:23,626,706...23,637,955
Ensembl chr20:23,626,706...23,638,473
JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 IAGP DNA:SNP:3'UTR:rs3087243(human) RGD PMID:19092854 RGD:11344911 NCBI chr 2:203,867,771...203,873,965
Ensembl chr 2:203,867,771...203,873,965
JBrowse link
G CTNNA1 catenin alpha 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 5:138,753,425...138,935,034
Ensembl chr 5:138,610,967...138,935,034
JBrowse link
G CTSH cathepsin H EXP CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr15:78,921,058...78,945,089
Ensembl chr15:78,921,058...78,949,574
JBrowse link
G CTSZ cathepsin Z EXP CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr20:58,995,185...59,007,254
Ensembl chr20:58,995,185...59,007,254
Ensembl chr20:58,995,185...59,007,254
JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 treatment
disease_progression
IMP
IEP
RGD PMID:26031918, PMID:24035716 RGD:11352265, RGD:11352273 NCBI chr 2:136,114,349...136,118,149
Ensembl chr 2:136,114,349...136,118,149
Ensembl chr 2:136,114,349...136,118,149
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 disease_progression
no_association
IAGP DNA:SNP: :6235T>C (human)
DNA:polymorphism: :6235T>C (human)
DNA:SNP: :4889A>G (human)
RGD PMID:19456854, PMID:15996939, PMID:19456854 RGD:10769358, RGD:11352736, RGD:10769358 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 susceptibility IAGP DNA:polymorphism:G15631T RGD PMID:19144407 RGD:6480472 NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398
JBrowse link
G CYP2D6 cytochrome P450 family 2 subfamily D member 6 susceptibility
treatment
IAGP DNA:polymorphisms: :
DNA:SNP: :(rs16947)(human)
RGD PMID:11037802, PMID:21518482 RGD:11352820, RGD:11352828 NCBI chr22:42,126,499...42,130,810
Ensembl chr22:42,126,499...42,130,881
Ensembl chr22:42,126,499...42,130,881
JBrowse link
G DAPK1 death associated protein kinase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19874806 NCBI chr 9:87,497,228...87,708,634
Ensembl chr 9:87,497,228...87,708,634
JBrowse link
G DDX41 DEAD-box helicase 41 IAGP ClinVar Annotator: match by term: Leukemia, acute myelogenous
ClinVar Annotator: match by term: Acute myeloid leukemia
ClinVar PMID:25741868 PMID:25920683 PMID:26712909 NCBI chr 5:177,511,577...177,516,961
Ensembl chr 5:177,511,577...177,516,961
JBrowse link
G DHX15 DEAH-box helicase 15 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27798625 PMID:29163777 NCBI chr 4:24,527,475...24,584,554
Ensembl chr 4:24,517,441...24,584,554
JBrowse link
G DLEC1 DLEC1 cilia and flagella associated protein treatment IDA DNA:hypermethylation:promoter: RGD PMID:27168825 RGD:11252164 NCBI chr 3:38,038,595...38,124,025
Ensembl chr 3:38,039,205...38,124,025
JBrowse link
G DLEU2 deleted in lymphocytic leukemia 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21441929 NCBI chr13:49,982,549...50,125,541
Ensembl chr13:49,956,670...50,125,720
JBrowse link
G DNMT1 DNA methyltransferase 1 IEP mRNA:increased expression:CD34+ bone marrow cells RGD PMID:11222358 RGD:9588667 NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,345...10,231,286
Ensembl chr19:10,133,345...10,231,286
JBrowse link
G DNMT3A DNA methyltransferase 3 alpha disease_progression
susceptibility
treatment
IEP
IAGP
IDA
mRNA:increased expression:CD34+ bone marrow cells
ClinVar Annotator: match by term: Acute myeloid leukemia
DNA:missense mutation:exon:p.R882 (human)
associated with Myelodysplastic Syndromes; DNA:mutations:cds:
DNA:hypomethylation: :
DNA:mutation::
ClinVar
OMIM
PMID:21067377 PMID:21518476 PMID:22160010 PMID:22722925 PMID:22744846 PMID:22898539 PMID:22898540 PMID:22898541 PMID:24606448 PMID:24622842 PMID:24656771 PMID:25741868 PMID:26619011 PMID:26876596 PMID:27991732 PMID:28432085 PMID:28492532 PMID:28941052 PMID:32581362, PMID:11222358, PMID:24512939, PMID:21415852, PMID:26242829, PMID:25609058, PMID:22291079 RGD:9588667, RGD:11041123, RGD:11041122, RGD:11041121, RGD:11041120, RGD:9589067 NCBI chr 2:25,227,874...25,342,590
Ensembl chr 2:25,227,855...25,342,590
JBrowse link
G DNMT3B DNA methyltransferase 3 beta susceptibility
disease_progression
IEP
IAGP
mRNA:increased expression:CD34+ bone marrow cells
DNA:SNP:promoter: C>T46359(human)
DNA:SNPs,haplotype: :rs1569686,rs2424908, rs6087990, rs6119954(human)
RGD PMID:11222358, PMID:16194411, PMID:24069326, PMID:23251566 RGD:9588667, RGD:9589108, RGD:9589103, RGD:9589071 NCBI chr20:32,762,385...32,809,356
Ensembl chr20:32,762,385...32,809,356
JBrowse link
G EHD3 EH domain containing 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 2:31,234,152...31,269,451
Ensembl chr 2:31,234,152...31,269,451
JBrowse link
G EHMT2 euchromatic histone lysine methyltransferase 2 disease_progression ISO
EXP
CTD Direct Evidence: marker/mechanism CTD PMID:24532712, PMID:24532712 RGD:9589168 NCBI chr 6:31,879,759...31,897,698
Ensembl chr 6:31,879,759...31,897,687
JBrowse link
G EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19458359 NCBI chr 8:38,030,534...38,060,365
Ensembl chr 8:38,030,534...38,060,365
JBrowse link
G ENAH ENAH actin regulator EXP CTD Direct Evidence: marker/mechanism CTD PMID:26237430 NCBI chr 1:225,486,829...225,660,046
Ensembl chr 1:225,486,835...225,653,142
JBrowse link
G ENO2 enolase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr12:6,914,580...6,923,697
Ensembl chr12:6,913,745...6,923,698
JBrowse link
G EPHX1 epoxide hydrolase 1 no_association IAGP
EXP
DNA:SNPs:exon:rs1051740, rs2234922 (human)
CTD Direct Evidence: marker/mechanism
DNA:missense mutations:exon:p.Y113H, p.H139R (human)
DNA:polymorphism
CTD PMID:29605894, PMID:22200898, PMID:11849215, PMID:20731606 RGD:11252114, RGD:11252119, RGD:11252115 NCBI chr 1:225,810,124...225,845,563
Ensembl chr 1:225,810,092...225,845,563
Ensembl chr 1:225,810,092...225,845,563
JBrowse link
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit treatment
no_association
IEP
IAGP
DNA:polymorphism: :p.R399Q (human)
DNA:SNP: :p.Q504K (human)
RGD PMID:18604718, PMID:23397959, PMID:16507781, PMID:20141440, PMID:21942242 RGD:11252170, RGD:11252193, RGD:11252179, RGD:11252173, RGD:11252171 NCBI chr19:45,407,334...45,451,547
Ensembl chr19:45,407,333...45,478,828
Ensembl chr19:45,407,333...45,478,828
JBrowse link
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit disease_progression
no_association
IAGP DNA:polymorphism: :p.K751Q (rs13181) (human)
DNA:SNPs, haplotypes: :p.D312N, p.K751Q (human)
associated with Myeloproliferative Disorders;DNA:polymorphism: :p.K751Q (rs13181) (human)
RGD PMID:20141440, PMID:21394217, PMID:22496165, PMID:23397959 RGD:11252173, RGD:11252209, RGD:11252198, RGD:11252193 NCBI chr19:45,349,837...45,370,647
Ensembl chr19:45,349,837...45,370,918
JBrowse link
G ERG ETS transcription factor ERG EXP CTD Direct Evidence: marker/mechanism CTD PMID:19822134 NCBI chr21:38,367,261...38,661,783
Ensembl chr21:38,380,027...38,661,780
JBrowse link
G ETV6 ETS variant transcription factor 6 IAGP DNA:translocation: :t(5;12)(q31;p13) (human)
ClinVar Annotator: match by term: Acute myeloid leukemia
ClinVar Annotator: match by term: Leukemia, acute myelogenous
DNA:deletion: :
ClinVar
OMIM
PMID:15806161 PMID:25581430 PMID:25807284 PMID:31248877, PMID:10502316, PMID:12161353, PMID:9171997 RGD:1599805, RGD:10450603, RGD:10450601 NCBI chr12:11,649,601...11,895,386
Ensembl chr12:11,649,674...11,895,377
Ensembl chr12:11,649,674...11,895,377
JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit disease_progression
susceptibility
ISO
IEP
IAGP
mRNA:increased expression:bone marrow, mononuclear cell (human)
DNA:mutations:cds:multiple (human)
RGD PMID:22677129, PMID:21125401, PMID:23099237 RGD:10450874, RGD:10450887, RGD:10450876 NCBI chr 7:148,807,374...148,884,344
Ensembl chr 7:148,807,383...148,884,321
Ensembl chr 7:148,807,383...148,884,321
JBrowse link
G F3 coagulation factor III, tissue factor IEP RGD PMID:2617479 RGD:11340207 NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759
JBrowse link
G FADD Fas associated via death domain disease_progression IEP RGD PMID:15520222 RGD:11341799 NCBI chr11:70,203,296...70,207,390
Ensembl chr11:70,203,163...70,207,390
Ensembl chr11:70,203,163...70,207,390
JBrowse link
G FANCA FA complementation group A IAGP DNA, mRNA:deletions, decreased expression: :multiple RGD PMID:14749703 RGD:11344889 NCBI chr16:89,737,549...89,816,647
Ensembl chr16:89,737,549...89,816,657
JBrowse link
G FANCC FA complementation group C susceptibility IAGP DNA:polymorphism:cds:p.S26F (human) RGD PMID:12670332 RGD:11046259 NCBI chr 9:95,099,054...95,317,730
Ensembl chr 9:95,099,054...95,426,796
JBrowse link
G FAS Fas cell surface death receptor susceptibility IAGP
EXP
IEP
DNA:polymorphism, haplotype:promoter:-1377 G>A, -670 G>A (human)
CTD Direct Evidence: marker/mechanism
CTD PMID:7579353, PMID:12907599, PMID:8870373 RGD:11049150, RGD:11049452 NCBI chr10:88,968,429...89,017,059
Ensembl chr10:88,990,531...89,017,059
JBrowse link
G FERMT2 FERM domain containing kindlin 2 disease_progression IEP RGD PMID:22391155 RGD:11352307 NCBI chr14:52,857,271...52,951,050
Ensembl chr14:52,857,268...52,952,435
JBrowse link
G FERMT3 FERM domain containing kindlin 3 disease_progression IEP RGD PMID:22391155 RGD:11352307 NCBI chr11:64,205,920...64,223,891
Ensembl chr11:64,206,678...64,223,886
Ensembl chr11:64,206,678...64,223,886
JBrowse link
G FGFR1 fibroblast growth factor receptor 1 treatment IMP RGD PMID:27005999, PMID:23777766, PMID:22683780 RGD:11352310, RGD:11352670, RGD:11352665 NCBI chr 8:38,411,143...38,468,635
Ensembl chr 8:38,400,215...38,468,834
JBrowse link
G FHL2 four and a half LIM domains 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 2:105,357,712...105,438,529
Ensembl chr 2:105,357,712...105,438,513
JBrowse link
G FLT3 fms related receptor tyrosine kinase 3 treatment
disease_progression
IAGP
EXP
ISO
IEP
ClinVar Annotator: match by term: Leukemia, acute myeloid, reduced survival in, somatic
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Acute myeloid leukemia
ClinVar Annotator: match by term: Leukemia, acute myelogenous
DNA:missense mutation:exon:p.D835Y,D835H(human)
DNA:mutations:cds:
DNA:duplication mutation:cds:
mRNA,protein:increased expression:bone marrow:
ClinVar
CTD
OMIM
PMID:11091200 PMID:11290608 PMID:11442493 PMID:12384447 PMID:14604974 PMID:14670924 PMID:14737077 PMID:15256420 PMID:15374878 PMID:15625552 PMID:15667533 PMID:15863200 PMID:16091740 PMID:16371029 PMID:16410449 PMID:16573742 PMID:16857985 PMID:16990784 PMID:17047150 PMID:17050201 PMID:17184839 PMID:17387224 PMID:17606455 PMID:17889720 PMID:17942876 PMID:19602710 PMID:19657110 PMID:19822134 PMID:19840437 PMID:20733134 PMID:21441929 PMID:21482694 PMID:21928377 PMID:22368270 PMID:22409268 PMID:22504183 PMID:22504184 PMID:22504185 PMID:22504186 PMID:23036488 PMID:23261068 PMID:23321257 PMID:23430109 PMID:23714533 PMID:23783394 PMID:23878140 PMID:23906301 PMID:24046014 PMID:24526162 PMID:24619500 PMID:25053825 PMID:25157968 PMID:27099147 PMID:27992414, PMID:11290608, PMID:11442493, PMID:23969938, PMID:24184354, PMID:16642044, PMID:8562934 RGD:1598955, RGD:11049497, RGD:11049482, RGD:11049471, RGD:11049467, RGD:11049466 NCBI chr13:28,003,274...28,100,587
Ensembl chr13:28,003,274...28,100,592
JBrowse link
G FOXO1 forkhead box O1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr13:40,555,667...40,666,641
Ensembl chr13:40,555,667...40,666,641
Ensembl chr13:40,555,667...40,666,641
JBrowse link
G FXYD6 FXYD domain containing ion transport regulator 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr11:117,836,981...117,877,430
Ensembl chr11:117,836,976...117,877,486
JBrowse link
G GAS2L1 growth arrest specific 2 like 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr22:29,306,650...29,312,787
Ensembl chr22:29,306,582...29,312,785
JBrowse link
G GATA1 GATA binding protein 1 disease_progression IEP RGD PMID:7579412 RGD:10450754 NCBI chr  X:48,786,590...48,794,311
Ensembl chr  X:48,786,562...48,794,311
Ensembl chr  X:48,786,562...48,794,311
JBrowse link
G GATA2 GATA binding protein 2 disease_progression IAGP
EXP
IEP
ClinVar Annotator: match by term: Acute myeloid leukemia
ClinVar Annotator: match by term: Leukemia, acute myeloid, susceptibility to
CTD Direct Evidence: marker/mechanism
mRNA:decreased expression:CD34+ bone marrow cell:
ClinVar
CTD
OMIM
PMID:20040766 PMID:21242295 PMID:21670465 PMID:21765025 PMID:21892158 PMID:21892162 PMID:22147895 PMID:23365458 PMID:25676417 PMID:25741868 PMID:28166811 PMID:28492532, PMID:25241285, PMID:22786876, PMID:24514424 RGD:11049510, RGD:11049515, RGD:11049514 NCBI chr 3:128,479,422...128,493,201
Ensembl chr 3:128,479,427...128,493,201
Ensembl chr 3:128,479,427...128,493,201
JBrowse link
G GFI1 growth factor independent 1 transcriptional repressor susceptibility IAGP
EXP
DNA:SNP:cds:c.107G>A(rs34631763)(human)
CTD Direct Evidence: marker/mechanism
CTD PMID:17330099, PMID:20075157 RGD:11040450 NCBI chr 1:92,473,043...92,486,925
Ensembl chr 1:92,473,043...92,486,925
JBrowse link
G GFI1B growth factor independent 1B transcriptional repressor IEP mRNA:increased expression:bone marrow cell: RGD PMID:17156408 RGD:11040507 NCBI chr 9:132,945,531...132,991,697
Ensembl chr 9:132,944,000...132,991,687
JBrowse link
G GPATCH1 G-patch domain containing 1 IAGP ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:28492532 NCBI chr19:33,081,168...33,130,542
Ensembl chr19:33,080,899...33,130,542
JBrowse link
G GPI glucose-6-phosphate isomerase IEP protein:increased expression:plasma: RGD PMID:6589021 RGD:11051848 NCBI chr19:34,353,330...34,402,413
Ensembl chr19:34,359,480...34,402,413
JBrowse link
G GPX1 glutathione peroxidase 1 disease_progression
treatment
susceptibility
IAGP
IDA
DNA:SNP: :c.599C>T (rs1050450) (human)
DNA:polymorphism: :p.P198L (human)
RGD PMID:26950655, PMID:22930375, PMID:26823947 RGD:11061784, RGD:11352817, RGD:11061561 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,176...49,358,358
Ensembl chr 3:49,357,176...49,358,358
JBrowse link
G GSKIP GSK3B interacting protein IAGP ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar NCBI chr14:96,363,526...96,387,290
Ensembl chr14:96,363,452...96,387,288
JBrowse link
G GSR glutathione-disulfide reductase IEP RGD PMID:24191316 RGD:11059506 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
JBrowse link
G GSTM1 glutathione S-transferase mu 1 susceptibility
disease_progression
IAGP DNA:methylation: :
DNA:deletion: : (human)
RGD PMID:11488937, PMID:22924777, PMID:18035413 RGD:10450822, RGD:10755405, RGD:10755318 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039
JBrowse link
G GSTP1 glutathione S-transferase pi 1 susceptibility IAGP chemotherapy-induced;
DNA:polymorphism:cds:p.I105V(human)
RGD PMID:11553769, PMID:11906705, PMID:21729529 RGD:10755420, RGD:10755328, RGD:10755422 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656
Ensembl chr11:67,583,742...67,586,656
JBrowse link
G GSTT1 glutathione S-transferase theta 1 no_association
disease_progression
susceptibility
IAGP DNA:deletion: : (human) RGD PMID:9164324, PMID:18035413, PMID:11488937 RGD:10450779, RGD:10755318, RGD:10450822
G GTF2I general transcription factor IIi EXP CTD Direct Evidence: marker/mechanism CTD PMID:18206229 NCBI chr 7:74,657,718...74,760,692
Ensembl chr 7:74,650,231...74,760,692
JBrowse link
G H1-0 H1.0 linker histone EXP CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr22:37,805,229...37,807,432
Ensembl chr22:37,805,093...37,807,436
Ensembl chr22:37,805,093...37,807,436
JBrowse link
G H1-2 H1.2 linker histone, cluster member EXP CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 6:26,055,740...26,056,470
Ensembl chr 6:26,055,787...26,056,428
Ensembl chr 6:26,055,787...26,056,428
JBrowse link
G HGF hepatocyte growth factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:22683780 NCBI chr 7:81,699,006...81,770,438
Ensembl chr 7:81,699,010...81,770,438
JBrowse link
G HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 IAGP RGD PMID:20051322, PMID:17237562 RGD:11041763, RGD:11041776 NCBI chr 6:32,659,467...32,666,657
Ensembl chr 6:32,659,467...32,668,383
JBrowse link
G HMOX1 heme oxygenase 1 ISO mRNA:increased expression:brain, spleen RGD PMID:19268504 RGD:10755700 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,207
Ensembl chr22:35,380,361...35,394,207
JBrowse link
G HOXA9 homeobox A9 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22541086 NCBI chr 7:27,162,438...27,165,537
Ensembl chr 7:27,162,438...27,175,180
JBrowse link
G HRAS HRas proto-oncogene, GTPase IAGP ClinVar Annotator: match by term: Leukemia, acute myelogenous
ClinVar Annotator: match by term: Acute myelogenous leukemia
ClinVar Annotator: match by term: Acute myelocytic leukemia
ClinVar Annotator: match by term: Acute myeloid leukemia
ClinVar PMID:11150980 PMID:12835555 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 PMID:16443854 PMID:16835863 PMID:16881968 PMID:16969868 PMID:17054105 PMID:17211612 PMID:17384584 PMID:17412879 PMID:17979197 PMID:18039947 PMID:18042262 PMID:18247425 PMID:18978862 PMID:19206176 PMID:19213030 PMID:19255327 PMID:19371735 PMID:19382114 PMID:19669404 PMID:19773371 PMID:20660566 PMID:20859122 PMID:20979192 PMID:21438134 PMID:21495179 PMID:21686750 PMID:21834037 PMID:21850009 PMID:22087699 PMID:22256804 PMID:22317973 PMID:22495892 PMID:22499344 PMID:22683711 PMID:22726224 PMID:22926243 PMID:23093928 PMID:23096712 PMID:23406027 PMID:23429430 PMID:23751039 PMID:23884457 PMID:24006476 PMID:24033266 PMID:24129065 PMID:24169525 PMID:24224811 PMID:24390138 PMID:24803665 PMID:25157968 PMID:25326635 PMID:25741868 PMID:25914166 PMID:26619011 PMID:27195699 PMID:27589201 PMID:28027064 PMID:28139825 PMID:28492532 PMID:29493581 PMID:31394527 PMID:31775759 PMID:168335863 NCBI chr11:532,242...535,576
Ensembl chr11:532,242...537,287
Ensembl chr11:532,242...537,287
JBrowse link
G HSPB1 heat shock protein family B (small) member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 7:76,302,673...76,304,292
Ensembl chr 7:76,302,673...76,304,295
JBrowse link
G ID2 inhibitor of DNA binding 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 2:8,682,056...8,684,461
Ensembl chr 2:8,678,845...8,684,461
JBrowse link
G IDH1 isocitrate dehydrogenase (NADP(+)) 1 disease_progression IAGP
EXP
DNA:mutation:cds:p.R132(human)
ClinVar Annotator: match by term: Acute myeloid leukemia
ClinVar Annotator: match by term: Acute myelogenous leukemia
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Leukemia, acute myelogenous
DNA:SNP::105C>T (rs11554137)(human)
ClinVar
CTD
PMID:18772396 PMID:19657110 PMID:19798509 PMID:19818334 PMID:20946881 PMID:21352804 PMID:21446021 PMID:22160010 PMID:22397365 PMID:22417203 PMID:22898539 PMID:23558169 PMID:24606448 PMID:25043048 PMID:25157968 PMID:25324972 PMID:25741868 PMID:26619011 PMID:27992414 PMID:27993330 PMID:29950729, PMID:20368543, PMID:25324972 RGD:11522718, RGD:11522721 NCBI chr 2:208,236,227...208,255,071
Ensembl chr 2:208,236,229...208,266,074
Ensembl chr 2:208,236,229...208,266,074
JBrowse link
G IDH2 isocitrate dehydrogenase (NADP(+)) 2 disease_progression IAGP
EXP
DNA:mutation:cds:p.R172(human)
ClinVar Annotator: match by term: Acute myelogenous leukemia
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Acute myeloid leukemia
DNA:mutation:cds:p.R140 (human)
ClinVar
CTD
PMID:20171147 PMID:20847235 PMID:20946881 PMID:21250968 PMID:21596855 PMID:21889589 PMID:21997850 PMID:22160010 PMID:22397365 PMID:22417203 PMID:22616558 PMID:22898539 PMID:23558173 PMID:23815907 PMID:23949315 PMID:24049096 PMID:24606448 PMID:25157968 PMID:25324972 PMID:25326635 PMID:25398939 PMID:25741868 PMID:26619011 PMID:27992414 PMID:28492532, PMID:20368543, PMID:25324972 RGD:11522718, RGD:11522721 NCBI chr15:90,083,045...90,102,468
Ensembl chr15:90,083,045...90,102,504
Ensembl chr15:90,083,045...90,102,504
JBrowse link
G IFI30 IFI30 lysosomal thiol reductase EXP CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr19:18,173,813...18,178,117
Ensembl chr19:18,173,162...18,178,117
JBrowse link
G IL10 interleukin 10 disease_progression IEP RGD PMID:23357299 RGD:11046264 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G IL1A interleukin 1 alpha treatment IDA RGD PMID:2460157 RGD:11051965 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
JBrowse link
G IL4R interleukin 4 receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:11918534 NCBI chr16:27,313,668...27,364,778
Ensembl chr16:27,313,668...27,364,778
JBrowse link
G IL6 interleukin 6 disease_progression
treatment
IEP
IMP
human protein in a rat model RGD PMID:23357299, PMID:8892684 RGD:11046264, RGD:11062010 NCBI chr 7:22,725,889...22,732,002
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G INPP4B inositol polyphosphate-4-phosphatase type II B EXP CTD Direct Evidence: marker/mechanism CTD PMID:29415082 NCBI chr 4:142,023,160...142,846,535
Ensembl chr 4:142,023,160...142,847,432
JBrowse link
G INSL6 insulin like 6 IAGP ClinVar Annotator: match by term: Leukemia, acute myelogenous
ClinVar Annotator: match by term: Acute myelogenous leukemia
ClinVar PMID:15781101 PMID:15793561 PMID:15858187 PMID:16081687 PMID:16247455 PMID:16293597 PMID:16325696 PMID:16603627 PMID:16707754 PMID:16709929 PMID:16762626 PMID:17989398 PMID:18256599 PMID:18394554 PMID:19036091 PMID:19287384 PMID:19293426 PMID:20339092 PMID:20631743 PMID:20703299 PMID:21120162 PMID:21689158 PMID:22041374 PMID:22422826 PMID:22571758 PMID:22818858 PMID:22829971 PMID:23115274 PMID:24404189 PMID:24986690 PMID:25043017 PMID:25157968 PMID:25671252 PMID:25741868 PMID:32581362 NCBI chr 9:4,992,409...5,185,707
Ensembl chr 9:5,123,880...5,185,647
JBrowse link
G ITGAV integrin subunit alpha V treatment IMP RGD PMID:23770013 RGD:10755448 NCBI chr 2:186,590,056...186,680,901
Ensembl chr 2:186,590,056...186,680,901
JBrowse link
G ITGB3 integrin subunit beta 3 treatment IMP
ISO
RGD PMID:23770013, PMID:23770013 RGD:10755448, RGD:10755448 NCBI chr17:47,253,827...47,313,743
Ensembl chr17:47,253,846...47,313,735
Ensembl chr17:47,253,846...47,313,735
Ensembl chr17:47,253,846...47,313,735
JBrowse link
G JAK1 Janus kinase 1 IAGP ClinVar Annotator: match by term: Leukemia, acute myelogenous ClinVar PMID:16239216 PMID:19139102 PMID:19470474 PMID:19838194 PMID:21436584 PMID:21680795 NCBI chr 1:64,833,229...65,067,746
Ensembl chr 1:64,833,229...65,067,754
JBrowse link
G JAK2 Janus kinase 2 IAGP
EXP
ClinVar Annotator: match by term: Leukemia, acute myelogenous
ClinVar Annotator: match by term: Acute myelogenous leukemia
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
OMIM
PMID:15781101 PMID:15793561 PMID:15858187 PMID:16081687 PMID:16247455 PMID:16293597 PMID:16325696 PMID:16603627 PMID:16707754 PMID:16709929 PMID:16762626 PMID:17989398 PMID:18256599 PMID:18394554 PMID:19036091 PMID:19287384 PMID:19293426 PMID:20339092 PMID:20631743 PMID:20703299 PMID:21120162 PMID:21689158 PMID:22041374 PMID:22422826 PMID:22571758 PMID:22818858 PMID:22829971 PMID:23115274 PMID:24404189 PMID:24986690 PMID:25043017 PMID:25157968 PMID:25671252 PMID:25741868 PMID:32581362 NCBI chr 9:4,984,390...5,129,948
Ensembl chr 9:4,984,390...5,128,183
Ensembl chr 9:4,984,390...5,128,183
JBrowse link
G KAT6A lysine acetyltransferase 6A IAGP human gene in a mouse model;DNA:translocation:exon RGD PMID:12676584 RGD:9590334 NCBI chr 8:41,929,479...42,051,988
Ensembl chr 8:41,929,479...42,051,994
JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase IAGP ClinVar Annotator: match by term: Acute myelocytic leukemia
ClinVar Annotator: match by term: Acute myeloid leukemia
OMIM
ClinVar
PMID:7479840 PMID:7513208 PMID:7691885 PMID:8589724 PMID:9657776 PMID:9827716 PMID:9990072 PMID:11380399 PMID:11493470 PMID:15685537 PMID:15790786 PMID:15972446 PMID:16352739 PMID:16384925 PMID:16731599 PMID:16741525 PMID:16912224 PMID:17259998 PMID:17699867 PMID:18024392 PMID:18986703 PMID:19164557 PMID:19262599 PMID:19865100 PMID:21642685 PMID:21689725 PMID:22504184 PMID:22932406 PMID:23149070 PMID:23582185 PMID:23714533 PMID:24045550 PMID:25157968 PMID:25741868 PMID:26158763 PMID:26822237 PMID:27777718 PMID:28492532 NCBI chr 4:54,657,957...54,740,715
Ensembl chr 4:54,657,918...54,740,715
JBrowse link
G KLF1 Kruppel like factor 1 disease_progression IEP RGD PMID:19097174 RGD:10769344 NCBI chr19:12,884,422...12,887,201
Ensembl chr19:12,884,422...12,887,201
Ensembl chr19:12,884,422...12,887,201
JBrowse link
G KMT2A lysine methyltransferase 2A IAGP
EXP
DNA:rearrangements
CTD Direct Evidence: marker/mechanism
CTD PMID:10339604 PMID:26237430, PMID:8361504 RGD:1625285 NCBI chr11:118,436,492...118,526,832
Ensembl chr11:118,436,490...118,526,832
JBrowse link
G KMT2B lysine methyltransferase 2B susceptibility ISO RGD PMID:25079327 RGD:9588599 NCBI chr19:35,717,818...35,738,878
Ensembl chr19:35,717,973...35,738,878
Ensembl chr19:35,717,973...35,738,878
JBrowse link
G KMT2C lysine methyltransferase 2C EXP CTD Direct Evidence: marker/mechanism CTD PMID:24794707 NCBI chr 7:152,134,925...152,436,642
Ensembl chr 7:152,134,922...152,436,003
Ensembl chr 7:152,134,922...152,436,003
Ensembl chr 7:152,134,922...152,436,003
Ensembl chr 7:152,134,922...152,436,003
JBrowse link
G KRAS KRAS proto-oncogene, GTPase IAGP OMIM:601626 DNA:insertion:CDS:amino acid Gly11ins
ClinVar Annotator: match by term: Acute myeloblastic leukemia
ClinVar Annotator: match by term: Acute myelogenous leukemia
ClinVar Annotator: match by term: Leukemia, acute myelogenous
ClinVar
OMIM
PMID:2278970 PMID:2547513 PMID:3122217 PMID:3627975 PMID:7773929 PMID:8439212 PMID:8955068 PMID:12460918 PMID:15696205 PMID:15842656 PMID:16361624 PMID:16434492 PMID:16618717 PMID:17332249 PMID:17384584 PMID:17704260 PMID:17910045 PMID:18316791 PMID:18794081 PMID:19018267 PMID:19029981 PMID:19047918 PMID:19075190 PMID:19114683 PMID:19255327 PMID:19358724 PMID:19679400 PMID:19773371 PMID:19881948 PMID:20609353 PMID:20805368 PMID:20921462 PMID:20921465 PMID:20949522 PMID:20978259 PMID:21063026 PMID:21079152 PMID:21169357 PMID:21228335 PMID:21398618 PMID:21975775 PMID:22025163 PMID:22235099 PMID:22392911 PMID:22407852 PMID:22499344 PMID:22571758 PMID:22683711 PMID:22722830 PMID:22734028 PMID:22897852 PMID:23014527 PMID:23096712 PMID:23182985 PMID:23325582 PMID:23406027 PMID:24033266 PMID:24558511 PMID:24720724 PMID:25044103 PMID:25157968 PMID:25695684 PMID:25705018 PMID:25741868 PMID:25808193 PMID:26372703 PMID:26619011 PMID:26623049 PMID:28492532 PMID:29298116 PMID:31891627 PMID:32581362, PMID:8955068, PMID:21283084 RGD:1600469, RGD:11060151 NCBI chr12:25,205,246...25,250,929
Ensembl chr12:25,205,246...25,250,936
JBrowse link
G LOC100507346 uncharacterized LOC100507346 IAGP ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:25741868 PMID:28492532 PMID:28873162 NCBI chr 9:95,463,609...95,470,019 JBrowse link
G LOC107984703 uncharacterized LOC107984703 IAGP ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar NCBI chr14:95,715,483...95,756,779 JBrowse link
G LOC112272571 Sharpr-MPRA regulatory region 11883 IAGP ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar NCBI chr14:96,363,212...96,363,506 JBrowse link
G LPAR1 lysophosphatidic acid receptor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 9:110,873,252...111,038,998
Ensembl chr 9:110,873,263...111,038,458
Ensembl chr 9:110,873,263...111,038,458
JBrowse link
G LPP LIM domain containing preferred translocation partner in lipoma IAGP ClinVar Annotator: match by term: Acute myeloid leukemia OMIM
ClinVar
PMID:25741868 NCBI chr 3:188,152,152...188,890,671
Ensembl chr 3:188,153,284...188,890,671
JBrowse link
G LRP3 LDL receptor related protein 3 IAGP ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:28492532 NCBI chr19:33,194,330...33,208,864
Ensembl chr19:33,177,603...33,208,864
JBrowse link
G LRRC56 leucine rich repeat containing 56 IAGP ClinVar Annotator: match by term: Leukemia, acute myelogenous
ClinVar Annotator: match by term: Acute myelogenous leukemia
ClinVar Annotator: match by term: Acute myelocytic leukemia
ClinVar Annotator: match by term: Acute myeloid leukemia
ClinVar PMID:11150980 PMID:12835555 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 PMID:16443854 PMID:16835863 PMID:16881968 PMID:16969868 PMID:17054105 PMID:17211612 PMID:17384584 PMID:17412879 PMID:17979197 PMID:18039947 PMID:18042262 PMID:18247425 PMID:18978862 PMID:19206176 PMID:19213030 PMID:19255327 PMID:19371735 PMID:19382114 PMID:19669404 PMID:19773371 PMID:20660566 PMID:20859122 PMID:20979192 PMID:21438134 PMID:21495179 PMID:21686750 PMID:21834037 PMID:21850009 PMID:22087699 PMID:22256804 PMID:22317973 PMID:22495892 PMID:22499344 PMID:22683711 PMID:22726224 PMID:22926243 PMID:23093928 PMID:23096712 PMID:23406027 PMID:23429430 PMID:23751039 PMID:23884457 PMID:24006476 PMID:24033266 PMID:24129065 PMID:24169525 PMID:24224811 PMID:24390138 PMID:24803665 PMID:25157968 PMID:25326635 PMID:25741868 PMID:25914166 PMID:26619011 PMID:27195699 PMID:27589201 PMID:28027064 PMID:28139825 PMID:28492532 PMID:29493581 PMID:31394527 PMID:31775759 PMID:168335863 NCBI chr11:518,967...554,916
Ensembl chr11:537,527...554,912
JBrowse link
G LYL1 LYL1 basic helix-loop-helix family member EXP CTD Direct Evidence: marker/mechanism CTD PMID:16094422 NCBI chr19:13,099,033...13,102,858
Ensembl chr19:13,099,033...13,103,161
JBrowse link
G MALAT1 metastasis associated lung adenocarcinoma transcript 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:29119387 NCBI chr11:65,497,738...65,506,516
Ensembl chr11:65,497,688...65,506,516
JBrowse link
G MDM2 MDM2 proto-oncogene disease_progression IEP RGD PMID:11064355 RGD:11251749 NCBI chr12:68,808,149...68,850,686
Ensembl chr12:68,808,177...68,850,686
Ensembl chr12:68,808,177...68,850,686
JBrowse link
G MECOM MDS1 and EVI1 complex locus EXP CTD Direct Evidence: marker/mechanism CTD PMID:30472098 NCBI chr 3:169,083,506...169,663,781
Ensembl chr 3:169,083,499...169,663,775
JBrowse link
G MEFV MEFV innate immuity regulator, pyrin susceptibility IAGP DNA:polymorphisms:cds:p.M694V,E148Q(human) RGD PMID:22351163 RGD:11531114 NCBI chr16:3,242,027...3,256,776
Ensembl chr16:3,242,027...3,256,633
Ensembl chr16:3,242,027...3,256,633
JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase EXP CTD Direct Evidence: marker/mechanism CTD PMID:22683780 NCBI chr 7:116,672,196...116,798,386
Ensembl chr 7:116,672,196...116,798,386
Ensembl chr 7:116,672,196...116,798,386
JBrowse link
G MIR155 microRNA 155 IEP miRNA:increased expression:blood
miRNA:decreased expression:peripheral blood mononuclear cell
RGD PMID:28989535, PMID:26923190 RGD:24922214, RGD:25671477 NCBI chr21:25,573,980...25,574,044
Ensembl chr21:25,573,980...25,574,044
JBrowse link
G MIR181A1HG MIR181A1 host gene IAGP ClinVar Annotator: match by term: Acute myeloid leukemia with maturation ClinVar PMID:29254171 NCBI chr 1:198,808,003...198,937,429
Ensembl chr 1:198,777,861...198,937,471
JBrowse link
G MLF1 myeloid leukemia factor 1 TAS
IAGP
DNA:translocation:fusion_protein
ClinVar Annotator: match by term: Acute myeloid leukemia
ClinVar PMID:25741868, PMID:15659732 RGD:1600902 NCBI chr 3:158,571,194...158,606,456
Ensembl chr 3:158,571,163...158,607,252
JBrowse link
G MLLT10 MLLT10 histone lysine methyltransferase DOT1L cofactor IAGP ClinVar Annotator: match by term: Acute myeloid leukemia OMIM
ClinVar
PMID:25741868 NCBI chr10:21,524,616...21,743,630
Ensembl chr10:21,524,646...21,743,630
JBrowse link
G MN1 MN1 proto-oncogene, transcriptional regulator EXP CTD Direct Evidence: marker/mechanism CTD PMID:19822134 NCBI chr22:27,748,277...27,801,756
Ensembl chr22:27,748,277...27,801,756
JBrowse link
G MTHFR methylenetetrahydrofolate reductase IAGP DNA:SNPs: :677C>T, 1298A>C(human) RGD PMID:17156840 RGD:10449408 NCBI chr 1:11,785,723...11,806,103
Ensembl chr 1:11,785,723...11,806,455
Ensembl chr 1:11,785,723...11,806,455
JBrowse link
G MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase susceptibility IAGP DNA:polymorphism: :66A>G(human) RGD PMID:18774170 RGD:11075096 NCBI chr 5:7,851,186...7,901,124
Ensembl chr 5:7,851,186...7,906,025
JBrowse link
G MX1 MX dynamin like GTPase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr21:41,420,329...41,459,214
Ensembl chr21:41,420,304...41,459,214
Ensembl chr21:41,420,304...41,459,214
JBrowse link
G MYBL2 MYB proto-oncogene like 2 ISS OMIM:601626 MouseDO NCBI chr20:43,667,114...43,716,482
Ensembl chr20:43,667,019...43,716,495
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:25956709 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
JBrowse link
G MYH11 myosin heavy chain 11 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18206229 PMID:27798625 NCBI chr16:15,703,135...15,857,032
Ensembl chr16:15,703,135...15,857,028
JBrowse link
G NAT2 N-acetyltransferase 2 susceptibility
no_association
IAGP DNA:polymorphisms,haplotype: :
DNA:polymorphism: :
RGD PMID:21888617, PMID:11352872 RGD:11532769, RGD:11532773 NCBI chr 8:18,386,585...18,401,219
Ensembl chr 8:18,391,282...18,401,218
JBrowse link
G NCOA2 nuclear receptor coactivator 2 IAGP human gene in a mouse model;DNA:translocation:exon RGD PMID:12676584 RGD:9590334 NCBI chr 8:70,109,770...70,405,390
Ensembl chr 8:70,109,782...70,403,808
JBrowse link
G NECTIN2 nectin cell adhesion molecule 2 EXP CTD Direct Evidence: therapeutic CTD PMID:29855615 NCBI chr19:44,846,297...44,889,223
Ensembl chr19:44,846,175...44,889,223
JBrowse link
G NF1 neurofibromin 1 disease_progression
severity
IEP
EXP
IAGP
CTD Direct Evidence: marker/mechanism
DNA:deletion: :
CTD PMID:21441929 PMID:25822087, PMID:12518368, PMID:23460398 RGD:12754447, RGD:12789444 NCBI chr17:31,094,927...31,377,677
Ensembl chr17:31,094,927...31,382,116
JBrowse link
G NOS3 nitric oxide synthase 3 disease_progression IAGP DNA:polymorphgism: : 894 G>T(human) RGD PMID:24684492 RGD:11533640 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588
JBrowse link
G NPM1 nucleophosmin 1 onset
disease_progression
IAGP
EXP
ISO
IDA
IMP
TAS
DNA:tandem_duplication:cytoplasmic_localization
ClinVar Annotator: match by term: Acute myeloid leukemia
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Leukemia, acute myelogenous
DNA:mutation:exon:
DNA:translocation:fusion_protein
ClinVar
CTD
OMIM
PMID:15659725 PMID:19657110 PMID:19822134 PMID:20026798 PMID:21441929 PMID:23877794 PMID:27992414 PMID:30420649 PMID:32581362, PMID:15659725, PMID:21441929, PMID:25992555, PMID:17957027, PMID:24184354, PMID:15659732 RGD:1600907, RGD:11534990, RGD:11070453, RGD:11049474, RGD:11049471, RGD:1600902 NCBI chr 5:171,387,116...171,410,900
Ensembl chr 5:171,387,116...171,411,137
Ensembl chr 5:171,387,116...171,411,137
JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 IAGP DNA:SNP: :609C>T (human) RGD PMID:19456854 RGD:10769358 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668
JBrowse link
G NRAS NRAS proto-oncogene, GTPase disease_progression IAGP
EXP
ISO
ClinVar Annotator: match by term: Acute myelogenous leukemia
ClinVar Annotator: match by term: Acute myelocytic leukemia
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Leukemia, acute myelogenous
ClinVar Annotator: match by term: Acute myeloid leukemia
DNA:missense mutation:cds:
ClinVar
CTD
PMID:1654209 PMID:2278970 PMID:2407301 PMID:2674680 PMID:2989702 PMID:3102434 PMID:3122217 PMID:6587382 PMID:8120410 PMID:10598665 PMID:10821536 PMID:12460918 PMID:12727991 PMID:14508525 PMID:14982869 PMID:15046639 PMID:15831708 PMID:15899789 PMID:15951308 PMID:16273091 PMID:16291983 PMID:16434492 PMID:16518851 PMID:17332249 PMID:17384584 PMID:17517660 PMID:17699718 PMID:18375819 PMID:18390968 PMID:18633438 PMID:18668139 PMID:18794081 PMID:18948947 PMID:18952898 PMID:19047918 PMID:19075190 PMID:19657110 PMID:19775298 PMID:19880792 PMID:19966803 PMID:20130576 PMID:20149136 PMID:20179705 PMID:20406486 PMID:20619739 PMID:20736745 PMID:21079152 PMID:21107323 PMID:21263000 PMID:21305640 PMID:21576590 PMID:21729679 PMID:21829508 PMID:22144181 PMID:22407852 PMID:22499344 PMID:22718121 PMID:22761467 PMID:22773810 PMID:22962325 PMID:23076151 PMID:23134356 PMID:23392294 PMID:23400451 PMID:23414587 PMID:23431193 PMID:23515407 PMID:23538902 PMID:23569304 PMID:23614898 PMID:24006476 PMID:24033266 PMID:24148783 PMID:24284627 PMID:24370118 PMID:24671188 PMID:25157968 PMID:25348872 PMID:25695684 PMID:26619011 PMID:26821351 PMID:27050078 PMID:27992414 PMID:27993330 PMID:28098151 PMID:28492532 PMID:28594414 PMID:28780248, PMID:21283084, PMID:18952898, PMID:25204082 RGD:11060151, RGD:11070616, RGD:11535045 NCBI chr 1:114,704,469...114,716,771
Ensembl chr 1:114,704,469...114,716,771
JBrowse link
G NSD1 nuclear receptor binding SET domain protein 1 severity IAGP DNA:translocations:multiple (human)
ClinVar Annotator: match by term: Acute myeloid leukemia
ClinVar PMID:15942875 PMID:25741868 PMID:28492532, PMID:23630019 RGD:9590149 NCBI chr 5:177,131,835...177,300,213
Ensembl chr 5:177,133,025...177,300,213
Ensembl chr 5:177,133,025...177,300,213
JBrowse link
G NTRK3 neurotrophic receptor tyrosine kinase 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:29119387 NCBI chr15:87,859,749...88,256,796
Ensembl chr15:87,859,751...88,256,768
JBrowse link
G NUP214 nucleoporin 214 IAGP OMIM NCBI chr 9:131,125,586...131,234,663
Ensembl chr 9:131,125,586...131,234,663
JBrowse link
G NUP98 nucleoporin 98 and 96 precursor EXP CTD Direct Evidence: marker/mechanism CTD PMID:21441929 NCBI chr11:3,675,010...3,797,554
Ensembl chr11:3,671,083...3,797,792
JBrowse link
G PAX5 paired box 5 IAGP ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:25741868 NCBI chr 9:36,833,269...37,034,268
Ensembl chr 9:36,833,269...37,034,268
JBrowse link
G PDCD1 programmed cell death 1 treatment ISO RGD PMID:26712908 RGD:41410789 NCBI chr 2:241,849,881...241,858,908
Ensembl chr 2:241,849,884...241,858,894
JBrowse link
G PDE4B phosphodiesterase 4B EXP CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 1:65,792,510...66,374,579
Ensembl chr 1:65,792,514...66,374,579
JBrowse link
G PICALM phosphatidylinositol binding clathrin assembly protein susceptibility IAGP DNA:inversion: :inv(11)(q14q23) OMIM PMID:12461747 RGD:1600760 NCBI chr11:85,957,175...86,069,860
Ensembl chr11:85,957,175...86,069,882
JBrowse link
G PIM2 Pim-2 proto-oncogene, serine/threonine kinase EXP CTD Direct Evidence: marker/mechanism CTD PMID:19458359 NCBI chr  X:48,913,182...48,919,024
Ensembl chr  X:48,913,182...48,919,024
JBrowse link
G PLCB1 phospholipase C beta 1 severity IEP mRNA:increased expression:blood (human) RGD PMID:20516454 RGD:11535940 NCBI chr20:8,132,266...8,884,900
Ensembl chr20:8,077,251...8,968,360
JBrowse link
G POU4F1 POU class 4 homeobox 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18206229 NCBI chr13:78,598,362...78,603,552
Ensembl chr13:78,598,362...78,603,552
JBrowse link
G PRAME PRAME nuclear receptor transcriptional regulator IEP mRNA:increased expression:bone marrow, mononuclear cell (human) RGD PMID:20376794 RGD:11535023 NCBI chr22:22,547,701...22,559,294
Ensembl chr22:22,547,701...22,559,361
JBrowse link
G PSIP1 PC4 and SFRS1 interacting protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 9:15,464,066...15,511,004
Ensembl chr 9:15,464,066...15,510,995
JBrowse link
G PTCH1 patched 1 IAGP ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:25741868 PMID:28492532 PMID:28873162 NCBI chr 9:95,442,980...95,516,971
Ensembl chr 9:95,442,980...95,517,057
JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 IAGP
EXP
ClinVar Annotator: match by term: Acute myeloid leukemia
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
PMID:12717436 PMID:14644997 PMID:15385933 PMID:15710330 PMID:15928039 PMID:16358218 PMID:17972951 PMID:19047918 PMID:19179468 PMID:24033266 PMID:25097206 PMID:25395418 PMID:26619011 PMID:27069254 PMID:27992414 PMID:28098151 PMID:30868567 NCBI chr12:112,418,915...112,509,918
Ensembl chr12:112,418,351...112,509,913
Ensembl chr12:112,418,351...112,509,913
JBrowse link
G PVR PVR cell adhesion molecule EXP CTD Direct Evidence: therapeutic CTD PMID:29855615 NCBI chr19:44,643,910...44,666,162
Ensembl chr19:44,643,798...44,666,162
JBrowse link
G PXDN peroxidasin EXP CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 2:1,631,887...1,744,852
Ensembl chr 2:1,631,887...1,744,852
JBrowse link
G RASGRP1 RAS guanyl releasing protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21441929 NCBI chr15:38,488,097...38,564,814
Ensembl chr15:38,488,103...38,565,575
JBrowse link
G RGS2 regulator of G protein signaling 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 1:192,809,039...192,812,275
Ensembl chr 1:192,809,039...192,812,275
JBrowse link
G RHPN2 rhophilin Rho GTPase binding protein 2 IAGP ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:28492532 NCBI chr19:32,978,592...33,064,888
Ensembl chr19:32,978,592...33,064,888
JBrowse link
G RTEL1 regulator of telomere elongation helicase 1 IAGP ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:25741868 NCBI chr20:63,657,810...63,696,253
Ensembl chr20:63,657,810...63,696,253
JBrowse link
G RTEL1-TNFRSF6B RTEL1-TNFRSF6B readthrough (NMD candidate) IAGP ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:25741868 NCBI chr20:63,657,810...63,698,698
Ensembl chr20:63,659,300...63,698,684
JBrowse link
G RUNX1 RUNX family transcription factor 1 disease_progression IAGP DNA:translocation
DNA:frameshift mutations, missense mutations, nonsense mutations: :multiple
RGD PMID:12760263, PMID:19808697, PMID:11023523 RGD:6482833, RGD:11251704, RGD:11251692 NCBI chr21:35,372,507...35,580,764
Ensembl chr21:34,787,801...36,004,667
JBrowse link
G RUNX1 RUNX family transcription factor 1 IAGP
EXP
ClinVar Annotator: match by term: Acute myeloid leukemia
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Leukemia, acute myeloid, m0 subtype
OMIM
ClinVar
CTD
PMID:10068652 PMID:10508512 PMID:11276260 PMID:12200707 PMID:12377125 PMID:12393679 PMID:12807882 PMID:15156185 PMID:17234761 PMID:18206229 PMID:19357396 PMID:19387465 PMID:19808697 PMID:20549580 PMID:20722699 PMID:22012064 PMID:23817177 PMID:24374719 PMID:24523240 PMID:24616160 PMID:24659740 PMID:25741868 PMID:25840971 PMID:27294619 PMID:27798625 PMID:28231333 PMID:28492532 PMID:28513614 PMID:30420649 PMID:31064749 PMID:32098966 NCBI chr21:34,787,801...35,049,334
Ensembl chr21:34,787,801...36,004,667
JBrowse link
G RUNX1T1 RUNX1 partner transcriptional co-repressor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18206229 PMID:27798625 NCBI chr 8:91,954,967...92,103,451
Ensembl chr 8:91,954,967...92,103,286
JBrowse link
G RUNX3 RUNX family transcription factor 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18206229 NCBI chr 1:24,899,511...24,965,158
Ensembl chr 1:24,899,511...24,965,121
JBrowse link
G S100A10 S100 calcium binding protein A10 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 1:151,982,915...151,993,859
Ensembl chr 1:151,982,915...151,993,859
JBrowse link
G S100A8 S100 calcium binding protein A8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21971985 NCBI chr 1:153,390,032...153,422,583
Ensembl chr 1:153,390,032...153,391,073
JBrowse link
G SEPTIN9 septin 9 EXP CTD Direct Evidence: marker/mechanism CTD PMID:10339604 NCBI chr17:77,281,499...77,500,596
Ensembl chr17:77,280,569...77,500,596
JBrowse link
G SF3B1 splicing factor 3b subunit 1 IAGP ClinVar Annotator: match by term: Acute myeloid leukemia
ClinVar Annotator: match by term: Leukemia, acute myelogenous
ClinVar PMID:21909114 PMID:21995386 PMID:23395771 PMID:23634996 PMID:26619011 NCBI chr 2:197,389,784...197,435,093
Ensembl chr 2:197,388,515...197,435,091
Ensembl chr 2:197,388,515...197,435,091
JBrowse link
G SF3B2 splicing factor 3b subunit 2 IAGP ClinVar Annotator: match by term: Leukemia, acute myelogenous ClinVar PMID:26619011 NCBI chr11:66,052,361...66,069,308
Ensembl chr11:66,050,729...66,069,308
JBrowse link
G SGK1 serum/glucocorticoid regulated kinase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 6:134,169,248...134,318,112
Ensembl chr 6:134,169,246...134,318,112
Ensembl chr 6:134,169,246...134,318,112
JBrowse link
G SH3GL1 SH3 domain containing GRB2 like 1, endophilin A2 IAGP ClinVar Annotator: match by term: Acute myeloid leukemia OMIM
ClinVar
PMID:25741868 NCBI chr19:4,360,369...4,400,547
Ensembl chr19:4,360,370...4,400,547
JBrowse link
G SLC7A10 solute carrier family 7 member 10 IAGP ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:28492532 NCBI chr19:33,208,664...33,225,850
Ensembl chr19:33,208,664...33,225,850
JBrowse link
G SOD2 superoxide dismutase 2 disease_progression IEP
IAGP
protein:increased expression:serum RGD PMID:1596865, PMID:16769586 RGD:11035286, RGD:11035289 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
Ensembl chr 6:159,669,069...159,762,529
Ensembl chr 6:159,669,069...159,762,529
JBrowse link
G SPARC secreted protein acidic and cysteine rich EXP CTD Direct Evidence: marker/mechanism CTD PMID:18206229 NCBI chr 5:151,661,096...151,686,915
Ensembl chr 5:151,661,096...151,686,975
JBrowse link
G SPI1 Spi-1 proto-oncogene EXP CTD Direct Evidence: marker/mechanism CTD PMID:26237430 NCBI chr11:47,354,859...47,395,640
Ensembl chr11:47,354,860...47,378,576
Ensembl chr11:47,354,860...47,378,576
JBrowse link
G SPRY4 sprouty RTK signaling antagonist 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25822087 NCBI chr 5:142,310,430...142,325,021
Ensembl chr 5:142,310,427...142,326,455
JBrowse link
G SRSF2 serine and arginine rich splicing factor 2 severity IAGP DNA:mutations:multiple (human) RGD PMID:22431577 RGD:11039017 NCBI chr17:76,734,115...76,737,411
Ensembl chr17:76,734,115...76,737,374
Ensembl chr17:76,734,115...76,737,374
JBrowse link
G SRSF4 serine and arginine rich splicing factor 4 IEP mRNA:decreased expression: (human) RGD PMID:22722453 RGD:11039059 NCBI chr 1:29,147,743...29,181,900
Ensembl chr 1:29,147,743...29,181,900
JBrowse link
G STAT3 signal transducer and activator of transcription 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19796711 NCBI chr17:42,313,324...42,388,502
Ensembl chr17:42,313,324...42,388,482
Ensembl chr17:42,313,324...42,388,482
Ensembl chr17:42,313,324...42,388,482
JBrowse link
G SVIL supervillin EXP CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr10:29,457,338...29,736,936
Ensembl chr10:29,457,338...29,736,781
Ensembl chr10:29,457,338...29,736,781
JBrowse link
G SYNGR1 synaptogyrin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr22:39,349,991...39,385,575
Ensembl chr22:39,349,925...39,385,575
JBrowse link
G TCEA2 transcription elongation factor A2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr20:64,042,350...64,072,347
Ensembl chr20:64,049,836...64,072,347
JBrowse link
G TCL1A TCL1 family AKT coactivator A IAGP ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar NCBI chr14:95,694,160...95,714,155
Ensembl chr14:95,709,947...95,714,196
JBrowse link
G TCN2 transcobalamin 2 IEP protein:increased expression:: RGD PMID:1059479 RGD:11060122 NCBI chr22:30,607,174...30,627,271
Ensembl chr22:30,607,003...30,627,271
JBrowse link
G TEK TEK receptor tyrosine kinase IAGP ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:19340004 NCBI chr 9:27,109,141...27,230,178
Ensembl chr 9:27,109,141...27,230,174
JBrowse link
G TERT telomerase reverse transcriptase disease_progression IEP
IAGP
ClinVar Annotator: match by term: Acute myeloid leukemia
ClinVar Annotator: match by term: Leukemia, acute myeloid, susceptibility to
ClinVar Annotator: match by term: Acute myelocytic leukemia
ClinVar Annotator: match by term: Leukemia, acute myelogenous
ClinVar
OMIM
PMID:15814878 PMID:17460043 PMID:18460650 PMID:18753630 PMID:18931339 PMID:19147845 PMID:19760749 PMID:19796246 PMID:20966039 PMID:21520173 PMID:21635204 PMID:22476886 PMID:23538340 PMID:23901009 PMID:24033266 PMID:24983628 PMID:25108601 PMID:25741868 PMID:26859482 PMID:28154186 PMID:28492532, PMID:23826993 RGD:11038655 NCBI chr 5:1,253,167...1,295,068
Ensembl chr 5:1,253,147...1,295,068
Ensembl chr 5:1,253,147...1,295,068
JBrowse link
G TET2 tet methylcytosine dioxygenase 2 disease_progression IAGP
IEP
DNA:deletions RGD PMID:23389918, PMID:25200248 RGD:11038681, RGD:11038682 NCBI chr 4:105,145,875...105,279,803
Ensembl chr 4:105,145,875...105,279,816
JBrowse link
G TFPI2 tissue factor pathway inhibitor 2 IAGP DNA:hypermethylation:promoter: RGD PMID:22052167 RGD:11060127 NCBI chr 7:93,885,396...93,890,753
Ensembl chr 7:93,885,396...93,890,753
JBrowse link
G TFR2 transferrin receptor 2 disease_progression IEP RGD PMID:15015967 RGD:11062090 NCBI chr 7:100,620,420...100,641,552
Ensembl chr 7:100,620,416...100,642,779
JBrowse link
G TGM6 transglutaminase 6 IAGP ClinVar Annotator: match by term: Leukemia, acute myelogenous ClinVar PMID:21106500 NCBI chr20:2,380,901...2,432,753
Ensembl chr20:2,380,901...2,432,753
JBrowse link
G TMEM127 transmembrane protein 127 IAGP ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:20923864 PMID:25741868 PMID:28492532 NCBI chr 2:96,248,514...96,265,997
Ensembl chr 2:96,248,516...96,265,994
Ensembl chr 2:96,248,516...96,265,994
JBrowse link
G TNFSF10 TNF superfamily member 10 EXP CTD Direct Evidence: therapeutic CTD PMID:12780785 NCBI chr 3:172,505,508...172,523,430
Ensembl chr 3:172,505,508...172,523,475
JBrowse link
G TNFSF8 TNF superfamily member 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:9058727 PMID:10512160 PMID:11918534 NCBI chr 9:114,893,343...114,930,674
Ensembl chr 9:114,893,343...114,930,595
JBrowse link
G TNFSF9 TNF superfamily member 9 IEP protein:increased expression:serum (human) RGD PMID:11564827 RGD:2317350 NCBI chr19:6,531,026...6,535,924
Ensembl chr19:6,531,026...6,535,924
JBrowse link
G TP53 tumor protein p53 disease_progression
treatment
IAGP
ISO
IEP
DNA:mutation: :
ClinVar Annotator: match by term: Acute myelogenous leukemia
ClinVar Annotator: match by term: Acute myeloid leukemia
ClinVar Annotator: match by term: Acute myelocytic leukemia
ClinVar Annotator: match by term: Leukemia, acute myelogenous
CTD Direct Evidence: marker/mechanism
DNA:mutations: :
ClinVar
CTD
PMID:1359493 PMID:1565143 PMID:1565144 PMID:1569604 PMID:1631137 PMID:1631151 PMID:1683921 PMID:1978757 PMID:2046748 PMID:2113594 PMID:2826609 PMID:7732013 PMID:7887414 PMID:7969167 PMID:8023157 PMID:8062826 PMID:8099841 PMID:8118819 PMID:8164043 PMID:8242631 PMID:8423216 PMID:8425176 PMID:8479749 PMID:8527048 PMID:8633021 PMID:9047394 PMID:9049183 PMID:9242456 PMID:9290701 PMID:9407971 PMID:9546439 PMID:9569050 PMID:9572492 PMID:9598730 PMID:9627118 PMID:9662334 PMID:9825943 PMID:10411893 PMID:10432928 PMID:10589545 PMID:10616528 PMID:10797439 PMID:10864200 PMID:10914716 PMID:10922393 PMID:11051239 PMID:11139324 PMID:11180592 PMID:11315715 PMID:11370630 PMID:11429705 PMID:11479205 PMID:11494139 PMID:11782540 PMID:11793474 PMID:11896595 PMID:11920959 PMID:12124823 PMID:12509279 PMID:12672316 PMID:12700230 PMID:12726864 PMID:12792784 PMID:12826609 PMID:12917626 PMID:14559903 PMID:15004724 PMID:15017592 PMID:15037740 PMID:15381368 PMID:15390294 PMID:15580553 PMID:15607980 PMID:15722483 PMID:15781620 PMID:15825182 PMID:15951970 PMID:15977174 PMID:16209708 PMID:16288208 PMID:16337994 PMID:16401470 PMID:16489069 PMID:16494995 PMID:16508005 PMID:16633321 PMID:16682957 PMID:16778209 PMID:16818505 PMID:16861262 PMID:17015838 PMID:17311302 PMID:17390010 PMID:17401428 PMID:17417627 PMID:17427234 PMID:17530187 PMID:17540308 PMID:17567834 PMID:17606709 PMID:17636407 PMID:17724467 PMID:17875924 PMID:18307025 PMID:18511570 PMID:18555592 PMID:18685109 PMID:19101993 PMID:19336573 PMID:19367569 PMID:19378321 PMID:19405127 PMID:19462533 PMID:19556618 PMID:19681600 PMID:19834951 PMID:19930417 PMID:20013323 PMID:20028212 PMID:20113312 PMID:20127978 PMID:20128691 PMID:20308654 PMID:20407015 PMID:20506564 PMID:20516128 PMID:20522432 PMID:20693561 PMID:20805372 PMID:21056685 PMID:21187651 PMID:21232794 PMID:21305319 PMID:21343334 PMID:21356188 PMID:21483000 PMID:21484931 PMID:21514416 PMID:21519010 PMID:21535297 PMID:21552135 PMID:21601526 PMID:21761402 PMID:22090360 PMID:22110706 PMID:22114072 PMID:22186996 PMID:22265402 PMID:22427690 PMID:22540896 PMID:22713868 PMID:22811390 PMID:22862161 PMID:22899716 PMID:22915647 PMID:22919068 PMID:22923379 PMID:22999923 PMID:23161690 PMID:23172776 PMID:23246812 PMID:23265383 PMID:23315175 PMID:23334668 PMID:23538418 PMID:23630318 PMID:23667202 PMID:23713777 PMID:23950206 PMID:23967324 PMID:24033266 PMID:24038938 PMID:24256616 PMID:24381225 PMID:24395441 PMID:24487413 PMID:24501221 PMID:24573247 PMID:24603336 PMID:24641375 PMID:24651012 PMID:24651015 PMID:24677579 PMID:24702488 PMID:24744791 PMID:24810334 PMID:25157968 PMID:25339994 PMID:25433984 PMID:25503501 PMID:25525159 PMID:25584008 PMID:25587027 PMID:25741868 PMID:25787918 PMID:25822087 PMID:25896519 PMID:25925845 PMID:25927356 PMID:25945745 PMID:25952993 PMID:26014290 PMID:26230955 PMID:26425688 PMID:26467025 PMID:26497680 PMID:26534844 PMID:26554828 PMID:26585234 PMID:26619011 PMID:26659639 PMID:26681312 PMID:26787237 PMID:26822237 PMID:26845104 PMID:27022024 PMID:27276561 PMID:27374712 PMID:27463065 PMID:27501770 PMID:27533082 PMID:27622479 PMID:27680515 PMID:27683180 PMID:27714481 PMID:27724982 PMID:27873457 PMID:27895058 PMID:27959731 PMID:28135145 PMID:28152038 PMID:28369373 PMID:28453743 PMID:28472496 PMID:28476805 PMID:28477316 PMID:28492532 PMID:28724667 PMID:28861920 PMID:28975465 PMID:29025599 PMID:29070607 PMID:29324801 PMID:29478780 PMID:29489754 PMID:29752822 PMID:29753700 PMID:29979965 PMID:30076369 PMID:30128536 PMID:30216591 PMID:30224644 PMID:30311369 PMID:30327374 PMID:30352134 PMID:30720243 PMID:30816478 PMID:30840781 PMID:31016814 PMID:31206626 PMID:31300551 PMID:31775759 PMID:32000721 PMID:32295079, PMID:24836762, PMID:25412846, PMID:25573287 RGD:11073714, RGD:11057925, RGD:11075071 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
Ensembl chr17:7,661,779...7,687,538
JBrowse link
G TRH thyrotropin releasing hormone EXP CTD Direct Evidence: marker/mechanism CTD PMID:18206229 NCBI chr 3:129,974,720...129,977,935
Ensembl chr 3:129,974,688...129,977,935
JBrowse link
G TRIO trio Rho guanine nucleotide exchange factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:18206229 NCBI chr 5:14,143,342...14,510,204
Ensembl chr 5:14,143,342...14,532,128
JBrowse link
G TSC1 TSC complex subunit 1 IAGP ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:25741868 PMID:28492532 NCBI chr 9:132,891,349...132,945,269
Ensembl chr 9:132,891,348...132,946,874
JBrowse link
G TSC2 TSC complex subunit 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19250671 NCBI chr16:2,047,804...2,089,491
Ensembl chr16:2,047,967...2,089,491
JBrowse link
G TUBB2A tubulin beta 2A class IIa EXP CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 6:3,153,666...3,157,544
Ensembl chr 6:3,153,666...3,157,544
Ensembl chr 6:3,153,666...3,157,544
JBrowse link
G TUNAR TCL1 upstream neural differentiation-associated RNA IAGP ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar NCBI chr14:95,876,392...95,925,571
Ensembl chr14:95,876,392...95,925,571
Ensembl chr14:95,876,392...95,925,571
JBrowse link
G TYMS thymidylate synthetase susceptibility IAGP DNA:repeats,insertion/deletion:5'UTR, 3'UTR: RGD PMID:18774170 RGD:11075096 NCBI chr18:657,653...673,578
Ensembl chr18:657,653...673,578
JBrowse link
G U2AF1 U2 small nuclear RNA auxiliary factor 1 IAGP ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:22158538 PMID:23029227 PMID:23861105 PMID:24498085 PMID:26619011 NCBI chr21:43,092,956...43,108,291
Ensembl chr21:43,092,956...43,107,570
Ensembl chr21:43,092,956...43,107,570
JBrowse link
G VEGFA vascular endothelial growth factor A disease_progression IAGP DNA:SNP,haplotype: :(rs3025039),(rs699947),(rs833061)(human) RGD PMID:17983459 RGD:13432134 NCBI chr 6:43,770,209...43,786,487
Ensembl chr 6:43,770,184...43,786,487
JBrowse link
G VOPP1 VOPP1 WW domain binding protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:18206229 NCBI chr 7:55,434,406...55,572,502
Ensembl chr 7:55,436,056...55,572,988
JBrowse link
G VSIG4 V-set and immunoglobulin domain containing 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18206229 NCBI chr  X:66,021,738...66,040,092
Ensembl chr  X:66,021,738...66,040,125
JBrowse link
G WDR88 WD repeat domain 88 IAGP ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:28492532 NCBI chr19:33,132,098...33,175,799
Ensembl chr19:33,132,090...33,175,799
JBrowse link
G WT1 WT1 transcription factor IAGP
EXP
ClinVar Annotator: match by term: Acute myeloid leukemia
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
PMID:19822134 PMID:24374862 PMID:24422723 PMID:24521058 PMID:24659740 PMID:24667279 PMID:24671364 PMID:25741868 PMID:27992414 NCBI chr11:32,387,775...32,435,539
Ensembl chr11:32,387,775...32,435,564
Ensembl chr11:32,387,775...32,435,564
JBrowse link
G ZBTB7A zinc finger and BTB domain containing 7A EXP CTD Direct Evidence: marker/mechanism CTD PMID:27798625 NCBI chr19:4,043,303...4,066,899
Ensembl chr19:4,043,303...4,066,899
JBrowse link
G ZFP91 ZFP91 zinc finger protein, atypical E3 ubiquitin ligase ISO RGD PMID:12738986 RGD:727221 NCBI chr11:58,579,063...58,621,550
Ensembl chr11:58,579,063...58,621,550
JBrowse link
Acute Myelomonocytic Leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARHGAP26 Rho GTPase activating protein 26 IAGP juvenile myelomonocytic leukemia, OMIM:607785 translocation t(5;11)(q31;q23) fusing ARHGAP26 to MLL in one allele and point mutation A1255G/Asn417Ser or one of two insertions in second allele RGD PMID:10908648 RGD:1599311 NCBI chr 5:142,770,370...143,229,011
Ensembl chr 5:142,770,377...143,229,011
JBrowse link
G CBFB core-binding factor subunit beta susceptibility IAGP
EXP
DNA:inversion: :inv(16)(p13q22)
CTD Direct Evidence: marker/mechanism
CTD PMID:10958941, PMID:8351518 RGD:1599543 NCBI chr16:67,029,149...67,101,058
Ensembl chr16:67,028,984...67,101,058
JBrowse link
G CDKN2B cyclin dependent kinase inhibitor 2B ISO RGD PMID:14681685 RGD:11252167 NCBI chr 9:22,002,903...22,009,313
Ensembl chr 9:22,002,903...22,009,305
JBrowse link
G FLT3 fms related receptor tyrosine kinase 3 treatment IMP RGD PMID:22187040 RGD:11049503 NCBI chr13:28,003,274...28,100,587
Ensembl chr13:28,003,274...28,100,592
JBrowse link
G GMPS guanine monophosphate synthase IAGP treatment-related acute type M4 myeloid leukemia; chromosomal translocation resulted in a fusion of MLL and GMPS genes RGD PMID:11110714 RGD:1598998 NCBI chr 3:155,869,430...155,944,020
Ensembl chr 3:155,870,650...155,944,020
JBrowse link
G KMT2A lysine methyltransferase 2A EXP CTD Direct Evidence: marker/mechanism CTD PMID:8282816 NCBI chr11:118,436,492...118,526,832
Ensembl chr11:118,436,490...118,526,832
JBrowse link
G MYH11 myosin heavy chain 11 EXP CTD Direct Evidence: marker/mechanism CTD PMID:10958941 NCBI chr16:15,703,135...15,857,032
Ensembl chr16:15,703,135...15,857,028
JBrowse link
acute promyelocytic leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:12556562 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751
JBrowse link
G AQP9 aquaporin 9 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23563754 NCBI chr15:58,138,169...58,185,911
Ensembl chr15:58,138,169...58,185,911
JBrowse link
G ASXL1 ASXL transcriptional regulator 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26285909 NCBI chr20:32,358,062...32,439,319
Ensembl chr20:32,358,330...32,439,319
JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27770503 NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636
JBrowse link
G CCL7 C-C motif chemokine ligand 7 IEP RGD PMID:19828696 RGD:5130982 NCBI chr17:34,270,221...34,272,242
Ensembl chr17:34,270,221...34,272,242
JBrowse link
G CD44 CD44 molecule (Indian blood group) EXP CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:16208414 PMID:17349212 NCBI chr11:35,139,168...35,232,402
Ensembl chr11:35,138,882...35,232,402
Ensembl chr11:35,138,882...35,232,402
JBrowse link
G CDKN2B cyclin dependent kinase inhibitor 2B disease_progression IDA DNA:hyprmethylation:promoter: RGD PMID:12750706 RGD:11252187 NCBI chr 9:22,002,903...22,009,313
Ensembl chr 9:22,002,903...22,009,305
JBrowse link
G CEBPA CCAAT enhancer binding protein alpha EXP CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:16788101 PMID:26285909 NCBI chr19:33,299,934...33,302,564
Ensembl chr19:33,299,934...33,302,534
JBrowse link
G CEBPE CCAAT enhancer binding protein epsilon EXP CTD Direct Evidence: therapeutic CTD PMID:16788101 NCBI chr14:23,117,306...23,119,255
Ensembl chr14:23,117,304...23,119,616
Ensembl chr14:23,117,304...23,119,616
JBrowse link
G DAPK2 death associated protein kinase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28978663 NCBI chr15:63,907,036...64,046,485
Ensembl chr15:63,907,036...64,072,033
JBrowse link
G DEFA3 defensin alpha 3 EXP CTD Direct Evidence: therapeutic CTD PMID:16019513 NCBI chr 8:7,015,869...7,018,336
Ensembl chr 8:7,015,869...7,018,297
JBrowse link
G DNMT3A DNA methyltransferase 3 alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:26285909 NCBI chr 2:25,227,874...25,342,590
Ensembl chr 2:25,227,855...25,342,590
JBrowse link
G F3 coagulation factor III, tissue factor IEP
EXP
CTD Direct Evidence: marker/mechanism CTD PMID:16206674, PMID:10726043 RGD:11340216 NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759
JBrowse link
G FLT3 fms related receptor tyrosine kinase 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17454189 PMID:24160850 PMID:26285909 NCBI chr13:28,003,274...28,100,587
Ensembl chr13:28,003,274...28,100,592
JBrowse link
G FNDC3B fibronectin type III domain containing 3B EXP CTD Direct Evidence: marker/mechanism CTD PMID:28314734 NCBI chr 3:172,039,578...172,401,669
Ensembl chr 3:172,039,578...172,401,669
JBrowse link
G GLI1 GLI family zinc finger 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23867347 NCBI chr12:57,459,785...57,472,451
Ensembl chr12:57,459,785...57,472,268
JBrowse link
G GLI2 GLI family zinc finger 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23867347 NCBI chr 2:120,735,868...120,992,653
Ensembl chr 2:120,735,623...120,992,653
JBrowse link
G GSTT1 glutathione S-transferase theta 1 susceptibility IAGP RGD PMID:21875282 RGD:10755406
G IDH1 isocitrate dehydrogenase (NADP(+)) 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26285909 NCBI chr 2:208,236,227...208,255,071
Ensembl chr 2:208,236,229...208,266,074
Ensembl chr 2:208,236,229...208,266,074
JBrowse link
G IDH2 isocitrate dehydrogenase (NADP(+)) 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26285909 NCBI chr15:90,083,045...90,102,468
Ensembl chr15:90,083,045...90,102,504
Ensembl chr15:90,083,045...90,102,504
JBrowse link
G IFNG interferon gamma EXP CTD Direct Evidence: marker/mechanism CTD PMID:22617429 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G IL17A interleukin 17A EXP CTD Direct Evidence: marker/mechanism CTD PMID:22617429 NCBI chr 6:52,186,375...52,190,638
Ensembl chr 6:52,186,375...52,190,638
JBrowse link
G IRF2BP2 interferon regulatory factor 2 binding protein 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25583766 NCBI chr 1:234,604,269...234,610,178
Ensembl chr 1:234,604,269...234,609,525
Ensembl chr 1:234,604,269...234,609,525
JBrowse link
G ITGAL integrin subunit alpha L EXP CTD Direct Evidence: marker/mechanism CTD PMID:16764927 NCBI chr16:30,472,683...30,523,185
Ensembl chr16:30,472,719...30,523,185
Ensembl chr16:30,472,719...30,523,185
JBrowse link
G ITGAM integrin subunit alpha M EXP CTD Direct Evidence: marker/mechanism CTD PMID:16764927 NCBI chr16:31,259,975...31,332,877
Ensembl chr16:31,259,967...31,332,892
JBrowse link
G ITGAX integrin subunit alpha X EXP CTD Direct Evidence: marker/mechanism CTD PMID:16764927 NCBI chr16:31,355,167...31,382,999
Ensembl chr16:31,355,134...31,382,997
Ensembl chr16:31,355,134...31,382,997
JBrowse link
G ITGB2 integrin subunit beta 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16764927 NCBI chr21:44,885,949...44,928,815
Ensembl chr21:44,885,953...44,931,989
JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase EXP CTD Direct Evidence: marker/mechanism CTD PMID:26285909 NCBI chr 4:54,657,957...54,740,715
Ensembl chr 4:54,657,918...54,740,715
JBrowse link
G KMT2E lysine methyltransferase 2E (inactive) severity IEP mRNA:decreased expression:peripheral blood, bone marrow, mononuclear cells (human) RGD PMID:24796963 RGD:9588539 NCBI chr 7:104,940,949...105,115,019
Ensembl chr 7:105,014,190...105,115,019
JBrowse link
G MIR15A microRNA 15a EXP CTD Direct Evidence: therapeutic CTD PMID:21056550 NCBI chr13:50,049,119...50,049,201
Ensembl chr13:50,049,119...50,049,201
JBrowse link
G MIR16-1 microRNA 16-1 EXP CTD Direct Evidence: therapeutic CTD PMID:21056550 NCBI chr13:50,048,973...50,049,061
Ensembl chr13:50,048,973...50,049,061
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor onset IMP
IEP
mRNA:increased expression:promyelocyte: RGD PMID:21059853, PMID:21059853 RGD:11532756, RGD:11532756 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
JBrowse link
G NCAM1 neural cell adhesion molecule 1 disease_progression IEP RGD PMID:24296270 RGD:40907062 NCBI chr11:112,961,420...113,278,436
Ensembl chr11:112,961,247...113,278,436
JBrowse link
G NPM1 nucleophosmin 1 TAS
EXP
DNA:translocation:fusion_protein
CTD Direct Evidence: marker/mechanism
CTD PMID:14508522 PMID:26285909, PMID:15659732 RGD:1600902 NCBI chr 5:171,387,116...171,410,900
Ensembl chr 5:171,387,116...171,411,137
Ensembl chr 5:171,387,116...171,411,137
JBrowse link
G NRAS NRAS proto-oncogene, GTPase EXP CTD Direct Evidence: marker/mechanism CTD PMID:26285909 NCBI chr 1:114,704,469...114,716,771
Ensembl chr 1:114,704,469...114,716,771
JBrowse link
G NUMA1 nuclear mitotic apparatus protein 1 IAGP OMIM NCBI chr11:72,002,864...72,080,686
Ensembl chr11:72,002,864...72,080,693
JBrowse link
G PLAT plasminogen activator, tissue type IEP protein:increased expression:leukocyte (human) RGD PMID:10861807 RGD:11541060 NCBI chr 8:42,174,718...42,207,565
Ensembl chr 8:42,174,718...42,207,676
Ensembl chr 8:42,174,718...42,207,676
JBrowse link
G PML PML nuclear body scaffold EXP
IMP
CTD Direct Evidence: marker/mechanism
human PML/RARA gene fusion in a mouse model
CTD PMID:8616088 PMID:10742073 PMID:14706140 PMID:16788101 PMID:16835227 PMID:16891316 PMID:16935935 PMID:17294898 PMID:17649720 PMID:19029980 PMID:19035177 PMID:19884644 PMID:19887701 PMID:21345080 PMID:21613260 PMID:22213200 PMID:23208507 PMID:23734343 PMID:26285909 PMID:26728337, PMID:9122233 RGD:41404695 NCBI chr15:73,994,716...74,047,827
Ensembl chr15:73,994,673...74,047,827
JBrowse link
G PRAME PRAME nuclear receptor transcriptional regulator severity IEP mRNA:increased expression:bone marrow (human) RGD PMID:18815192 RGD:11535037 NCBI chr22:22,547,701...22,559,294
Ensembl chr22:22,547,701...22,559,361
JBrowse link
G PRKAR1A protein kinase cAMP-dependent type I regulatory subunit alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:17712046 NCBI chr17:68,413,623...68,551,316
Ensembl chr17:68,511,780...68,551,319
JBrowse link
G RAP1GAP RAP1 GTPase activating protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:22614916 NCBI chr 1:21,596,221...21,669,413
Ensembl chr 1:21,596,215...21,669,363
JBrowse link
G RARA retinoic acid receptor alpha TAS
EXP
IAGP
DNA:translocation:fusion_protein
CTD Direct Evidence: marker/mechanism
CTD
OMIM
PMID:8616088 PMID:10742073 PMID:14508522 PMID:14706140 PMID:16239915 PMID:16788101 PMID:16835227 PMID:16891316 PMID:16935935 PMID:17294898 PMID:17649720 PMID:17712046 PMID:19029980 PMID:19035177 PMID:19884644 PMID:19887701 PMID:21613260 PMID:22213200 PMID:23208507 PMID:25583766 PMID:26285909 PMID:26728337 PMID:28314734, PMID:15659732 RGD:1600902 NCBI chr17:40,309,180...40,357,643
Ensembl chr17:40,309,180...40,357,643
JBrowse link
G SMO smoothened, frizzled class receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:23867347 NCBI chr 7:129,188,633...129,213,548
Ensembl chr 7:129,188,633...129,213,545
JBrowse link
G TET2 tet methylcytosine dioxygenase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26285909 NCBI chr 4:105,145,875...105,279,803
Ensembl chr 4:105,145,875...105,279,816
JBrowse link
G THBD thrombomodulin EXP CTD Direct Evidence: marker/mechanism CTD PMID:16206674 NCBI chr20:23,045,633...23,049,672
Ensembl chr20:23,045,633...23,049,672
Ensembl chr20:23,045,633...23,049,672
JBrowse link
G TMEM127 transmembrane protein 127 IAGP ClinVar Annotator: match by term: Acute promyelocytic leukemia ClinVar PMID:25741868 PMID:28492532 NCBI chr 2:96,248,514...96,265,997
Ensembl chr 2:96,248,516...96,265,994
Ensembl chr 2:96,248,516...96,265,994
JBrowse link
G TOP2A DNA topoisomerase II alpha IAGP ClinVar Annotator: match by term: Dna topoisomerase II, resistance to inhibition of, by amsacrine ClinVar PMID:1651812 NCBI chr17:40,388,525...40,417,902
Ensembl chr17:40,388,525...40,417,896
JBrowse link
G WT1 WT1 transcription factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:26285909 NCBI chr11:32,387,775...32,435,539
Ensembl chr11:32,387,775...32,435,564
Ensembl chr11:32,387,775...32,435,564
JBrowse link
G ZBTB16 zinc finger and BTB domain containing 16 IAGP
EXP
CTD Direct Evidence: marker/mechanism CTD PMID:23208507, PMID:8387545 RGD:1599922 NCBI chr11:114,059,576...114,256,770
Ensembl chr11:114,059,711...114,256,765
Ensembl chr11:114,059,711...114,256,765
JBrowse link
adult T-cell leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BIRC5 baculoviral IAP repeat containing 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16497974 NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636
JBrowse link
G BMP6 bone morphogenetic protein 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18688853 NCBI chr 6:7,726,099...7,881,728
Ensembl chr 6:7,726,099...7,881,728
JBrowse link
G CARD11 caspase recruitment domain family member 11 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr 7:2,906,142...3,043,867
Ensembl chr 7:2,906,141...3,043,945
Ensembl chr 7:2,906,141...3,043,945
JBrowse link
G CCR4 C-C motif chemokine receptor 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr 3:32,951,555...32,956,349
Ensembl chr 3:32,951,644...32,956,349
JBrowse link
G CCR7 C-C motif chemokine receptor 7 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr17:40,553,769...40,565,472
Ensembl chr17:40,553,769...40,565,472
JBrowse link
G CD163 CD163 molecule disease_progression IEP protein:increased expression:lymph node tumor (human) RGD PMID:23557330 RGD:42721976 NCBI chr12:7,470,811...7,503,808
Ensembl chr12:7,470,813...7,503,893
Ensembl chr12:7,470,813...7,503,893
JBrowse link
G CD274 CD274 molecule disease_progression IEP RGD PMID:27418641 RGD:41412177 NCBI chr 9:5,450,542...5,470,554
Ensembl chr 9:5,450,503...5,470,566
JBrowse link
G CD28 CD28 molecule EXP CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr 2:203,706,509...203,739,756
Ensembl chr 2:203,706,475...203,738,912
JBrowse link
G CD68 CD68 molecule disease_progression IEP protein:increased expression:lymph node tumor (human) RGD PMID:23557330 RGD:42721976 NCBI chr17:7,579,638...7,582,111
Ensembl chr17:7,579,491...7,582,111
JBrowse link
G CD80 CD80 molecule ISO RGD PMID:10590132 RGD:6902938 NCBI chr 3:119,524,293...119,559,614
Ensembl chr 3:119,524,293...119,559,614
JBrowse link
G CD86 CD86 molecule ISO RGD PMID:10590132 RGD:6902938 NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139
JBrowse link
G CSNK1A1 casein kinase 1 alpha 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr 5:149,492,982...149,551,439
Ensembl chr 5:149,492,982...149,551,471
JBrowse link
G CSNK2A1 casein kinase 2 alpha 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr20:472,498...543,790
Ensembl chr20:472,498...543,835
JBrowse link
G CSNK2B casein kinase 2 beta EXP CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr 6:31,666,080...31,670,067
Ensembl chr 6:31,665,236...31,670,343
Ensembl chr 6:31,665,236...31,670,343
Ensembl chr 6:31,665,236...31,670,343
JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr 2:203,867,771...203,873,965
Ensembl chr 2:203,867,771...203,873,965
JBrowse link
G FAS Fas cell surface death receptor susceptibility IAGP
IEP
DNA:polymorphism:promoter: -670 G>A(human)
protein:increased expression:peripheral blood mononuclear cell:
RGD PMID:17962369, PMID:7513372 RGD:11049147, RGD:11049453 NCBI chr10:88,968,429...89,017,059
Ensembl chr10:88,990,531...89,017,059
JBrowse link
G FOXP3 forkhead box P3 disease_progression EXP
IEP
CTD Direct Evidence: marker/mechanism CTD PMID:23962110, PMID:23797717 RGD:38456007 NCBI chr  X:49,250,436...49,264,932
Ensembl chr  X:49,250,438...49,270,477
Ensembl chr  X:49,250,438...49,270,477
JBrowse link
G FYN FYN proto-oncogene, Src family tyrosine kinase EXP CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr 6:111,660,332...111,873,452
Ensembl chr 6:111,660,332...111,873,452
JBrowse link
G GATA3 GATA binding protein 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr10:8,045,420...8,075,198
Ensembl chr10:8,045,378...8,075,198
JBrowse link
G GPR183 G protein-coupled receptor 183 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr13:99,294,273...99,307,399
Ensembl chr13:99,294,539...99,307,399
JBrowse link
G HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr 7:26,189,920...26,200,775
Ensembl chr 7:26,173,057...26,201,529
Ensembl chr 7:26,173,057...26,201,529
JBrowse link
G ICOS inducible T cell costimulator EXP CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr 2:203,936,763...203,961,577
Ensembl chr 2:203,936,763...203,961,577
Ensembl chr 2:203,936,763...203,961,577
JBrowse link
G IFNA1 interferon alpha 1 EXP CTD Direct Evidence: therapeutic CTD PMID:20370541 NCBI chr 9:21,440,439...21,441,316
Ensembl chr 9:21,440,439...21,441,316
JBrowse link
G IFNA2 interferon alpha 2 EXP CTD Direct Evidence: therapeutic CTD PMID:12560223 PMID:17077332 NCBI chr 9:21,384,255...21,385,398
Ensembl chr 9:21,384,255...21,385,398
JBrowse link
G IFNG interferon gamma treatment ISO
EXP
CTD Direct Evidence: marker/mechanism CTD PMID:23962110, PMID:8800741 RGD:10755707 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G IKZF2 IKAROS family zinc finger 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr 2:212,999,692...213,155,297
Ensembl chr 2:212,999,691...213,152,427
JBrowse link
G IL10 interleukin 10 IEP
EXP
CTD Direct Evidence: marker/mechanism CTD PMID:23962110, PMID:8704212 RGD:11049460 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G IL2 interleukin 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23962110 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725
JBrowse link
G IL4 interleukin 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23962110 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678
JBrowse link
G IL5 interleukin 5 disease_progression IEP protein:increased expression:serum RGD PMID:16425276 RGD:11354942 NCBI chr 5:132,539,194...132,556,864
Ensembl chr 5:132,541,445...132,556,838
JBrowse link
G IL6 interleukin 6 IEP protein:increased expression:serum (human) RGD PMID:10374863 RGD:11060275 NCBI chr 7:22,725,889...22,732,002
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G IRF4 interferon regulatory factor 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr 6:391,752...411,443
Ensembl chr 6:391,752...411,443
JBrowse link
G JAK3 Janus kinase 3 IAGP DNA:missense mutations: :p.L156P, p.R172Q, p.E183G (human) RGD PMID:21821710 RGD:11531131 NCBI chr19:17,824,782...17,848,071
Ensembl chr19:17,824,780...17,848,071
JBrowse link
G MYB MYB proto-oncogene, transcription factor disease_progression IEP mRNA:splice variants:CD4+ T cell: RGD PMID:27307595 RGD:11532670 NCBI chr 6:135,181,308...135,219,172
Ensembl chr 6:135,181,308...135,219,173
JBrowse link
G NOTCH1 notch receptor 1 IAGP DNA:mutations:multiple (human) RGD PMID:16707600 RGD:1580759 NCBI chr 9:136,494,433...136,546,048
Ensembl chr 9:136,494,433...136,546,048
JBrowse link
G NRAS NRAS proto-oncogene, GTPase disease_progression ISO RGD PMID:21586752 RGD:11535055 NCBI chr 1:114,704,469...114,716,771
Ensembl chr 1:114,704,469...114,716,771
JBrowse link
G PLCG1 phospholipase C gamma 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr20:41,137,519...41,177,626
Ensembl chr20:41,136,960...41,196,801
JBrowse link
G PRKCB protein kinase C beta EXP CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr16:23,835,983...24,220,611
Ensembl chr16:23,835,983...24,220,611
JBrowse link
G STAT3 signal transducer and activator of transcription 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24090995 NCBI chr17:42,313,324...42,388,502
Ensembl chr17:42,313,324...42,388,482
Ensembl chr17:42,313,324...42,388,482
Ensembl chr17:42,313,324...42,388,482
JBrowse link
G TAL2 TAL bHLH transcription factor 2 IAGP RGD PMID:1763056 RGD:1599285 NCBI chr 9:105,662,457...105,663,124
Ensembl chr 9:105,662,457...105,663,124
JBrowse link
G TERF2 telomeric repeat binding factor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17643074 NCBI chr16:69,355,567...69,386,007
Ensembl chr16:69,355,567...69,408,571
JBrowse link
G TLX1 T cell leukemia homeobox 1 IAGP
EXP
CTD Direct Evidence: marker/mechanism CTD PMID:1717256, PMID:1683261 RGD:1599439 NCBI chr10:101,130,773...101,137,789
Ensembl chr10:101,131,300...101,137,789
JBrowse link
G TNFSF8 TNF superfamily member 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:9058727 NCBI chr 9:114,893,343...114,930,674
Ensembl chr 9:114,893,343...114,930,595
JBrowse link
G TP53 tumor protein p53 IEA GAD PMID:15118671 RGD:1331525 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
Ensembl chr17:7,661,779...7,687,538
JBrowse link
G TP73 tumor protein p73 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr 1:3,652,516...3,736,201
Ensembl chr 1:3,652,516...3,736,201
JBrowse link
G VAV1 vav guanine nucleotide exchange factor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr19:6,772,708...6,857,366
Ensembl chr19:6,772,708...6,857,366
JBrowse link
alpha-thalassemia myelodysplasia syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATRX ATRX chromatin remodeler IAGP ClinVar Annotator: match by term: Acquired hemoglobin H disease
ClinVar Annotator: match by term: Alpha-thalassemia myelodysplasia syndrome
ClinVar
OMIM
PMID:9326931 PMID:10995512 PMID:12858175 PMID:16955409 PMID:20500465 PMID:24327140 PMID:25590979 PMID:25741868 PMID:28492532 PMID:31130284 NCBI chr  X:77,504,880...77,786,235
Ensembl chr  X:77,504,880...77,786,233
Ensembl chr  X:77,504,880...77,786,233
JBrowse link
AMED SYNDROME, DIGENIC term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide IAGP ClinVar Annotator: match by term: AMED SYNDROME, DIGENIC OMIM
ClinVar
PMID:33355142 NCBI chr 4:99,070,978...99,088,788
Ensembl chr 4:99,070,978...99,088,801
JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member IAGP ClinVar Annotator: match by term: BONE MARROW FAILURE SYNDROME 7, DIGENIC ClinVar PMID:2987944 PMID:4065146 PMID:6650498 PMID:7180842 PMID:7593603 PMID:8903321 PMID:10627091 PMID:10780266 PMID:15654505 PMID:16046871 PMID:16440063 PMID:17885622 PMID:18056758 PMID:20010786 PMID:33355142 NCBI chr12:111,766,933...111,817,532
Ensembl chr12:111,766,887...111,817,532
JBrowse link
anaplastic large cell lymphoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALK ALK receptor tyrosine kinase TAS
EXP
DNA:translocation:fusion_protein
CTD Direct Evidence: marker/mechanism
CTD PMID:16151469 PMID:19503098 PMID:21345110 PMID:22155737 PMID:22920921 PMID:22968692, PMID:15659732 RGD:1600902 NCBI chr 2:29,190,992...29,921,589
Ensembl chr 2:29,192,774...29,921,586
JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17157164 NCBI chr14:102,080,742...102,139,749
Ensembl chr14:102,080,738...102,139,699
Ensembl chr14:102,080,738...102,139,699
JBrowse link
G IRF4 interferon regulatory factor 4 IAGP DNA:translocation RGD PMID:18987657 RGD:11526155 NCBI chr 6:391,752...411,443
Ensembl chr 6:391,752...411,443
JBrowse link
G JUNB JunB proto-oncogene, AP-1 transcription factor subunit IEP RGD PMID:12145210 RGD:1549449 NCBI chr19:12,791,486...12,793,315
Ensembl chr19:12,791,486...12,793,315
JBrowse link
G NPM1 nucleophosmin 1 TAS DNA:translocation:fusion_protein RGD PMID:15659732 RGD:1600902 NCBI chr 5:171,387,116...171,410,900
Ensembl chr 5:171,387,116...171,411,137
Ensembl chr 5:171,387,116...171,411,137
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit EXP CTD Direct Evidence: marker/mechanism CTD PMID:17261581 NCBI chr11:65,653,601...65,662,946
Ensembl chr11:65,653,597...65,663,090
JBrowse link
G STAT3 signal transducer and activator of transcription 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22155737 NCBI chr17:42,313,324...42,388,502
Ensembl chr17:42,313,324...42,388,482
Ensembl chr17:42,313,324...42,388,482
Ensembl chr17:42,313,324...42,388,482
JBrowse link
G TNFRSF8 TNF receptor superfamily member 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:10908157 PMID:17261581 NCBI chr 1:12,063,303...12,144,213
Ensembl chr 1:12,063,303...12,144,207
JBrowse link
G TWIST1 twist family bHLH transcription factor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22155737 NCBI chr 7:19,113,047...19,117,636
Ensembl chr 7:19,020,991...19,117,636
JBrowse link
Anemia, Refractory, with Excess of Blasts term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BIRC5 baculoviral IAP repeat containing 5 IEP RGD PMID:18426652 RGD:11038658 NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636
JBrowse link
G C3 complement C3 disease_progression IEP RGD PMID:9741227 RGD:11041158 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562
JBrowse link
G CFB complement factor B disease_progression IEP RGD PMID:9741227 RGD:11041158 NCBI chr 6:31,946,095...31,952,084
Ensembl chr 6:31,945,650...31,952,084
JBrowse link
G TERT telomerase reverse transcriptase IEP RGD PMID:18426652 RGD:11038658 NCBI chr 5:1,253,167...1,295,068
Ensembl chr 5:1,253,147...1,295,068
Ensembl chr 5:1,253,147...1,295,068
JBrowse link
G TET2 tet methylcytosine dioxygenase 2 disease_progression IEP RGD PMID:25200248 RGD:11038682 NCBI chr 4:105,145,875...105,279,803
Ensembl chr 4:105,145,875...105,279,816
JBrowse link
atypical chronic myeloid leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FGFR1 fibroblast growth factor receptor 1 IMP RGD PMID:15050920 RGD:11352668 NCBI chr 8:38,411,143...38,468,635
Ensembl chr 8:38,400,215...38,468,834
JBrowse link
G SETBP1 SET binding protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23222956 NCBI chr18:44,680,072...45,068,510
Ensembl chr18:44,680,173...45,068,510
JBrowse link
autosomal dominant sideroblastic anemia 4 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSPA9 heat shock protein family A (Hsp70) member 9 IAGP ClinVar Annotator: match by term: Anemia, sideroblastic, autosomal dominant ClinVar
OMIM
PMID:3653362 PMID:26491070 NCBI chr 5:138,553,756...138,575,401
Ensembl chr 5:138,553,756...138,575,416
Ensembl chr 5:138,553,756...138,575,416
JBrowse link
autosomal recessive pyridoxine-refractory sideroblastic anemia 2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GLRX5 glutaredoxin 5 EXP CTD Direct Evidence: marker/mechanism CTD NCBI chr14:95,535,050...95,544,714
Ensembl chr14:95,533,503...95,544,724
JBrowse link
G SLC25A38 solute carrier family 25 member 38 IAGP ClinVar Annotator: match by term: Anemia, sideroblastic, pyridoxine-refractory, autosomal recessive
ClinVar Annotator: match by term: Anemia, sideroblastic, 2, pyridoxine-refractory
ClinVar Annotator: match by term: Sideroblastic anemia pyridoxine-refractory autosomal recessive
ClinVar
OMIM
PMID:19412178 PMID:21393332 PMID:25326635 PMID:25741868 PMID:25985931 PMID:28492532 NCBI chr 3:39,383,353...39,397,351
Ensembl chr 3:39,383,370...39,397,351
JBrowse link
autosomal recessive pyridoxine-refractory sideroblastic anemia 3 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GLRX5 glutaredoxin 5 IAGP ClinVar Annotator: match by term: Sideroblastic anemia 3, pyridoxine-refractory ClinVar
OMIM
PMID:17485548 PMID:20364084 PMID:25342667 PMID:25741868 PMID:26100117 PMID:30660387 NCBI chr14:95,535,050...95,544,714
Ensembl chr14:95,533,503...95,544,724
JBrowse link
Autosomal Sideroblastic Anemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARSA arylsulfatase A IAGP ClinVar Annotator: match by term: Autosomal recessive sideroblastic anemia ClinVar PMID:25741868 NCBI chr22:50,622,754...50,628,152
Ensembl chr22:50,622,754...50,628,173
JBrowse link
B-Cell Chronic Lymphocytic Leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCG2 ATP binding cassette subfamily G member 2 (Junior blood group) susceptibility IAGP DNA:SNPs,haplotype: :rs1481012,rs2231142(human) RGD PMID:21918980 RGD:11080977 NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628
JBrowse link
G ACOXL acyl-CoA oxidase like EXP CTD Direct Evidence: marker/mechanism CTD PMID:23770605 NCBI chr 2:110,732,539...111,120,610
Ensembl chr 2:110,732,573...111,118,548
Ensembl chr 2:110,732,573...111,118,548
Ensembl chr 2:110,732,573...111,118,548
JBrowse link
G AICDA activation induced cytidine deaminase disease_progression IEP RGD PMID:21133730 RGD:11039455 NCBI chr12:8,602,170...8,612,970
Ensembl chr12:8,602,170...8,612,867
JBrowse link
G APOE apolipoprotein E disease_progression IAGP RGD PMID:18784741 RGD:11040549 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393
JBrowse link
G ATM ATM serine/threonine kinase EXP CTD Direct Evidence: marker/mechanism CTD PMID:17968022 NCBI chr11:108,222,484...108,369,102
Ensembl chr11:108,222,832...108,369,102
Ensembl chr11:108,222,832...108,369,102
Ensembl chr11:108,222,832...108,369,102
JBrowse link
G BCL11A BAF chromatin remodeling complex subunit BCL11A IAGP DNA:translocation:5' utr: (human) RGD PMID:11719382 RGD:11100004 NCBI chr 2:60,450,520...60,553,654
Ensembl chr 2:60,450,520...60,554,467
JBrowse link
G BCL2 BCL2 apoptosis regulator treatment
severity
no_association
IMP
EXP
IEP
IAGP
CTD Direct Evidence: marker/mechanism
protein:increased expression:B cell (human)
DNA:snp:promoter:g.-938C>A (human)
CTD PMID:21750559 PMID:23770605, PMID:17296974, PMID:20001236, PMID:17959858, PMID:16960146 RGD:11522735, RGD:11526110, RGD:11526105, RGD:11526104 NCBI chr18:63,123,346...63,320,280
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BMF Bcl2 modifying factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:23770605 NCBI chr15:40,087,890...40,108,879
Ensembl chr15:40,087,890...40,108,892
JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase IAGP ClinVar Annotator: match by term: B-cell chronic lymphocytic leukemia
ClinVar Annotator: match by term: Leukemia, B-cell, chronic
ClinVar PMID:12068308 PMID:14612909 PMID:14679157 PMID:14688025 PMID:17096326 PMID:17119447 PMID:17311103 PMID:18368129 PMID:18794803 PMID:19383316 PMID:19537845 PMID:19913317 PMID:20350999 PMID:20619739 PMID:21129611 PMID:22310681 PMID:23352452 PMID:24033266 PMID:25157968 PMID:26619011 PMID:28492532 PMID:29595366 NCBI chr 7:140,713,328...140,924,929
Ensembl chr 7:140,719,327...140,924,929
Ensembl chr 7:140,719,327...140,924,929
JBrowse link
G BTK Bruton tyrosine kinase treatment IMP RGD PMID:23045577 RGD:11040699 NCBI chr  X:101,349,450...101,390,796
Ensembl chr  X:101,349,447...101,390,796
JBrowse link
G C11orf21 chromosome 11 open reading frame 21 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23770605 NCBI chr11:2,295,628...2,303,140
Ensembl chr11:2,295,645...2,303,049
Ensembl chr11:2,295,645...2,303,049
JBrowse link
G CBL Cbl proto-oncogene severity IEP
IDA
mRNA,protein:increased expression:CD5+ B cell:
DNA:hypophosphorylation:CD5+ B cell:
RGD PMID:17804547, PMID:17804547 RGD:11038803, RGD:11038803 NCBI chr11:119,206,339...119,308,149
Ensembl chr11:119,206,298...119,313,926
Ensembl chr11:119,206,298...119,313,926
JBrowse link
G CCDC50 coiled-coil domain containing 50 IDA RGD PMID:19641524 RGD:9685139 NCBI chr 3:191,329,082...191,398,659
Ensembl chr 3:191,329,085...191,398,659
JBrowse link
G CD40 CD40 molecule IMP RGD PMID:20616215 RGD:5490532 NCBI chr20:46,118,242...46,129,858
Ensembl chr20:46,118,278...46,129,863
JBrowse link
G CD40LG CD40 ligand IMP mouse-human chimeric gene in human RGD PMID:20882050 RGD:11352235 NCBI chr  X:136,648,158...136,660,390
Ensembl chr  X:136,648,158...136,660,390
Ensembl chr  X:136,648,158...136,660,390
JBrowse link
G CD5 CD5 molecule EXP CTD Direct Evidence: marker/mechanism CTD PMID:18006695 NCBI chr11:61,093,963...61,127,852
Ensembl chr11:61,102,489...61,127,852
JBrowse link
G CD79B CD79b molecule IEP protein:decreased expression:B lymphocyte, cell surface (human) RGD PMID:9269755 RGD:11250403 NCBI chr17:63,928,740...63,932,331
Ensembl chr17:63,928,740...63,932,354
Ensembl chr17:63,928,740...63,932,354
JBrowse link
G CD86 CD86 molecule severity IEP protein:increased expression:peripheral blood mononuclear cell (human) RGD PMID:25179679 RGD:11354969 NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139
JBrowse link
G CDKN2B-AS1 CDKN2B antisense RNA 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23770605 NCBI chr 9:21,994,791...22,121,097
Ensembl chr 9:21,994,139...22,128,103
JBrowse link
G CPEB1 cytoplasmic polyadenylation element binding protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20062064 NCBI chr15:82,543,201...82,648,795
Ensembl chr15:82,543,201...82,648,861
JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 IEP protein:increased expression:T cell RGD PMID:16094420, PMID:15914560 RGD:11344923, RGD:11352246 NCBI chr 2:203,867,771...203,873,965
Ensembl chr 2:203,867,771...203,873,965
JBrowse link
G DKC1 dyskerin pseudouridine synthase 1 IEP RGD PMID:18077792 RGD:11251735 NCBI chr  X:154,762,864...154,777,689
Ensembl chr  X:154,762,742...154,777,689
JBrowse link
G DNMT3B DNA methyltransferase 3 beta IEP mRNA:decreased expression: B cell RGD PMID:15467427 RGD:9589146 NCBI chr20:32,762,385...32,809,356
Ensembl chr20:32,762,385...32,809,356
JBrowse link
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit severity IAGP DNA:SNP: :p.K751Q (rs13181) (human) RGD PMID:22739018, PMID:19484764 RGD:11252203, RGD:11252204 NCBI chr19:45,349,837...45,370,647
Ensembl chr19:45,349,837...45,370,918
JBrowse link
G FARP2 FERM, ARH/RhoGEF and pleckstrin domain protein 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20062064 NCBI chr 2:241,356,285...241,494,841
Ensembl chr 2:241,356,285...241,494,841
JBrowse link
G FAS Fas cell surface death receptor disease_progression IEP RGD PMID:12901972 RGD:11049461 NCBI chr10:88,968,429...89,017,059
Ensembl chr10:88,990,531...89,017,059
JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 IAGP ClinVar Annotator: match by term: B-cell chronic lymphocytic leukemia ClinVar PMID:25741868 PMID:26619011 NCBI chr 4:152,320,544...152,536,873
Ensembl chr 4:152,320,544...152,536,092
JBrowse link
G FCGR3A Fc fragment of IgG receptor IIIa no_association IAGP DNA:SNP:exon:p.F158V (rs396991) (human) RGD PMID:14563637 RGD:11352260 NCBI chr 1:161,541,759...161,550,737
Ensembl chr 1:161,541,759...161,550,737
JBrowse link
G GNAS GNAS complex locus disease_progression IAGP DNA:polymorphism:393T>C (human) RGD PMID:17020971 RGD:1601379 NCBI chr20:58,839,681...58,911,192
Ensembl chr20:58,839,718...58,911,192
JBrowse link
G HRAS HRas proto-oncogene, GTPase IAGP ClinVar Annotator: match by term: B-cell chronic lymphocytic leukemia
ClinVar Annotator: match by term: Leukemia, B-cell, chronic
ClinVar PMID:12835555 PMID:16329078 PMID:16372351 PMID:16835863 PMID:17211612 PMID:17384584 PMID:18042262 PMID:19213030 PMID:19255327 PMID:19773371 PMID:20859122 PMID:21438134 PMID:21495179 PMID:21850009 PMID:22256804 PMID:22499344 PMID:22683711 PMID:22726224 PMID:23093928 PMID:23096712 PMID:23406027 PMID:23429430 PMID:23884457 PMID:24006476 PMID:24033266 PMID:24129065 PMID:24224811 PMID:24390138 PMID:25157968 PMID:25326635 PMID:25741868 PMID:26619011 PMID:28492532 PMID:29493581 PMID:31775759 PMID:168335863 NCBI chr11:532,242...535,576
Ensembl chr11:532,242...537,287
Ensembl chr11:532,242...537,287
JBrowse link
G ICAM1 intercellular adhesion molecule 1 severity IEP RGD PMID:7658704 RGD:11354983 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
JBrowse link
G IFNG interferon gamma susceptibility IAGP D