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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Hematologic Neoplasms
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Accession:DOID:9006532 term browser browse the term
Definition:Neoplasms located in the blood and blood-forming tissue (the bone marrow and lymphatic tissue). The commonest forms are the various types of LEUKEMIA, of LYMPHOMA, and of the progressive, life-threatening forms of the MYELODYSPLASTIC SYNDROMES.
Synonyms:exact_synonym: Hematological Neoplasms;   Hematopoietic Malignancies;   Hematopoietic Malignancy;   hematologic neoplasm;   hematological neoplasm;   hematopoietic neoplasm;   hematopoietic neoplasms
 primary_id: MESH:D019337
 alt_id: RDO:0007251
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
 
Hematologic Neoplasms term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22311042 NCBI chr14:13,644,891...13,852,829
Ensembl chr14:13,542,647...13,742,727
JBrowse link
G ABO ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase susceptibility ISO RGD PMID:19274076 RGD:11100003 NCBI chr 9:49,746,749...49,758,317
Ensembl chr 9:49,748,693...49,758,479
JBrowse link
G CBL Cbl proto-oncogene ISO ClinVar Annotator: match by term: Hematologic neoplasm ClinVar PMID:19571318 PMID:20543203 PMID:20694012 PMID:23696637 PMID:25283271 PMID:25952305 PMID:28414188 PMID:28492532 NCBI chr 5:14,600,409...14,676,974
Ensembl chr 5:14,607,013...14,676,956
JBrowse link
G CSF1R colony stimulating factor 1 receptor ISO ClinVar Annotator: match by term: Hematologic neoplasm ClinVar PMID:2406720 PMID:18971950 PMID:25157968 NCBI chr 4:58,980,699...59,010,683
Ensembl chr 4:58,980,788...59,010,510
JBrowse link
G ETV6 ETS variant transcription factor 6 ISO DNA:translocation: :
ClinVar Annotator: match by term: Hematologic neoplasm
CTD Direct Evidence: marker/mechanism
RGD
ClinVar
CTD
PMID:11319801 PMID:25581430 PMID:25807284 PMID:31248877 RGD:10450600 NCBI chr27:34,351,206...34,587,060
Ensembl chr27:34,343,390...34,587,060
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23777986 NCBI chr 9:57,850,870...57,855,607
Ensembl chr 9:57,850,922...57,855,257
JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase ISO ClinVar Annotator: match by term: Hematological neoplasm
ClinVar Annotator: match by term: Hematologic neoplasm
ClinVar PMID:7479840 PMID:7513208 PMID:7530509 PMID:7691885 PMID:8589724 PMID:9438854 PMID:9657776 PMID:9827716 PMID:9990072 PMID:10362788 PMID:11073817 PMID:11276010 PMID:11380399 PMID:11493470 PMID:11526490 PMID:15790786 PMID:15972446 PMID:16352739 PMID:16384925 PMID:16731599 PMID:16741525 PMID:16908931 PMID:16912224 PMID:17259998 PMID:17372901 PMID:17824795 PMID:18024392 PMID:18510589 PMID:18955458 PMID:18980976 PMID:18986703 PMID:19164557 PMID:19262599 PMID:19865100 PMID:20147452 PMID:20545949 PMID:21642685 PMID:21689725 PMID:21690468 PMID:22504184 PMID:23582185 PMID:23714533 PMID:24045550 PMID:25157968 PMID:25741868 PMID:26158763 PMID:26619011 PMID:26822237 PMID:27777718 PMID:28492532 NCBI chr13:47,108,442...47,190,935
Ensembl chr13:47,108,504...47,190,029
JBrowse link
G MEFV MEFV innate immuity regulator, pyrin susceptibility ISO DNA:mutations:cds:p.M694V,E148Q,M680I(human) RGD PMID:20518828 RGD:11531118 NCBI chr 6:37,964,776...37,984,830
Ensembl chr 6:37,970,608...37,983,737
JBrowse link
G MPL MPL proto-oncogene, thrombopoietin receptor ISO ClinVar Annotator: match by term: Hematologic neoplasm ClinVar PMID:16834459 PMID:16868251 PMID:25741868 NCBI chr15:16,815,102...16,825,321
Ensembl chr15:16,815,294...16,825,350
JBrowse link
G MTHFR methylenetetrahydrofolate reductase no_association
treatment
ISO DNA:SNP: :677C>T (human)
DNA:SNP: :1298A>C (human)
RGD PMID:21984221 RGD:10449413 NCBI chr 2:84,445,526...84,457,435
Ensembl chr 2:84,380,919...84,536,818
JBrowse link
G MUC1 mucin 1, cell surface associated ISO associated with Pneumonia, Pneumocystis; protein:increased expression:serum RGD PMID:12186700 RGD:5131276 NCBI chr 7:42,338,939...42,344,690
Ensembl chr 7:42,340,375...42,344,690
JBrowse link
G PON1 paraoxonase 1 susceptibility ISO CTD Direct Evidence: marker/mechanism
DNA:missense mutation:cds:p.Q192R (human)
CTD
RGD
PMID:22800774 RGD:11552572 NCBI chr14:20,565,620...20,600,774
Ensembl chr14:20,565,641...20,642,985
JBrowse link
Acute Erythroleukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DDX41 DEAD-box helicase 41 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30926971 NCBI chr 4:35,854,382...35,859,853
Ensembl chr 4:35,854,597...35,859,852
JBrowse link
G ERBB3 erb-b2 receptor tyrosine kinase 3 ISO ClinVar Annotator: match by term: Acute erythroleukemia ClinVar PMID:27416908 NCBI chr10:406,856...424,746
Ensembl chr10:406,633...424,264
JBrowse link
G FLT3 fms related receptor tyrosine kinase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30926971 NCBI chr25:11,551,372...11,670,891
Ensembl chr25:11,581,206...11,692,284
JBrowse link
G GFI1B growth factor independent 1B transcriptional repressor ISO mRNA:increased expression:bone marrow cell: RGD PMID:17156408 RGD:11040507 NCBI chr 9:51,380,697...51,394,679
Ensembl chr 9:51,380,696...51,392,812
JBrowse link
G HOXB9 homeobox B9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30926971 NCBI chr 9:24,884,101...24,889,904
Ensembl chr 9:24,872,950...24,889,376
JBrowse link
G KMT2A lysine methyltransferase 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:30926971 NCBI chr 5:15,212,559...15,302,825
Ensembl chr 5:15,217,348...15,270,971
JBrowse link
G NPM1 nucleophosmin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30926971 NCBI chr 4:40,756,464...40,770,174
Ensembl chr 4:40,756,465...40,770,175
JBrowse link
G NUP98 nucleoporin 98 and 96 precursor ISO CTD Direct Evidence: marker/mechanism CTD PMID:30926971 NCBI chr21:26,231,585...26,348,019
Ensembl chr21:26,220,963...26,336,020
JBrowse link
G RB1 RB transcriptional corepressor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30926971 NCBI chr22:3,061,621...3,204,625
Ensembl chr22:3,063,239...3,257,726
JBrowse link
G TP53 tumor protein p53 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30926971 NCBI chr 5:32,561,406...32,565,149
Ensembl chr 5:32,560,598...32,574,109
JBrowse link
acute leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit ISO ClinVar Annotator: match by term: Mixed Phenotype Acute Leukemia, T/Myeloid, Not Otherwise Specified ClinVar PMID:7585650 PMID:9195225 PMID:22234153 PMID:23221806 PMID:23232694 PMID:24728327 PMID:25716912 PMID:25741868 NCBI chr 1:110,173,781...110,191,612
Ensembl chr 1:110,173,715...110,190,125
JBrowse link
acute lymphoblastic leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 susceptibility ISO CTD Direct Evidence: marker/mechanism
DNA:snps, haplotype:multiple (human)
CTD
RGD
PMID:22674224 RGD:8657089 NCBI chr14:13,644,891...13,852,829
Ensembl chr14:13,542,647...13,742,727
JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 treatment ISO DNA:SNPs: :rs717620(human)
DNA:SNP:5'UTR:rs717620(human)
RGD PMID:24404132 PMID:25007187 RGD:11080959 RGD:11080979 NCBI chr28:12,670,885...12,740,124
Ensembl chr28:12,670,885...12,740,740
JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 disease_progression ISO mRNA:increased expression:mononuclear cell: RGD PMID:12100141 PMID:15521915 RGD:11081076 RGD:11081143 NCBI chr32:11,443,778...11,517,674
Ensembl chr32:11,443,780...11,517,674
JBrowse link
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:11984797 PMID:21898527 NCBI chr 9:53,118,462...53,262,092
Ensembl chr 9:53,119,641...53,261,307
JBrowse link
G ABO ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase susceptibility ISO RGD PMID:17065136 RGD:11100012 NCBI chr 9:49,746,749...49,758,317
Ensembl chr 9:49,748,693...49,758,479
JBrowse link
G AICDA activation induced cytidine deaminase treatment ISO RGD PMID:19759560 RGD:11039451 NCBI chr27:37,064,107...37,073,791
Ensembl chr27:37,064,080...37,073,789
JBrowse link
G ARID5B AT-rich interaction domain 5B ISO CTD Direct Evidence: marker/mechanism CTD PMID:19684603 PMID:19684604 NCBI chr 4:13,926,759...14,105,069
Ensembl chr 4:13,927,217...14,101,364
JBrowse link
G ARNT aryl hydrocarbon receptor nuclear translocator ISO CTD Direct Evidence: marker/mechanism CTD PMID:22674224 Ensembl chr17:59,941,353...60,010,867 JBrowse link
G BAX BCL2 associated X, apoptosis regulator susceptibility ISO CTD Direct Evidence: marker/mechanism OMIM
CTD
NCBI chr 1:107,423,388...107,426,464
Ensembl chr 1:107,422,424...107,426,464
JBrowse link
G BCL2 BCL2 apoptosis regulator severity ISO mRNA:increased expression:bone marrow (human) RGD PMID:25982455 RGD:11076595 NCBI chr 1:13,733,849...13,900,653
Ensembl chr 1:13,731,406...13,900,658
JBrowse link
G BCL2L1 BCL2 like 1 treatment ISO mRNA:increased expression:blood, mononuclear cell (human) RGD PMID:12469194 PMID:19020783 RGD:11353852 RGD:11353866 NCBI chr24:21,145,214...21,209,425
Ensembl chr24:21,145,215...21,196,355
JBrowse link
G BCR BCR activator of RhoGEF and GTPase susceptibility ISO CTD Direct Evidence: marker/mechanism OMIM
CTD
NCBI chr26:27,856,280...27,980,923
Ensembl chr26:27,856,082...27,978,318
JBrowse link
G CASP8 caspase 8 ISO CTD Direct Evidence: therapeutic CTD PMID:22010212 NCBI chr37:10,362,071...10,402,108
Ensembl chr37:10,391,048...10,401,822
JBrowse link
G CAST calpastatin ISO protein:increased expresssion:B cell RGD PMID:11264179 RGD:5509822 NCBI chr 3:12,920,514...13,031,974
Ensembl chr 3:12,922,453...13,031,959
JBrowse link
G CCND1 cyclin D1 ISO mRNA:increased expression:bone marrow (human) RGD PMID:22391157 RGD:11352824 NCBI chr18:48,501,905...48,509,684
Ensembl chr18:48,501,899...48,516,005
JBrowse link
G CD40LG CD40 ligand ISO RGD PMID:9292526 RGD:11352271 NCBI chr  X:107,001,421...107,023,007
Ensembl chr  X:107,010,890...107,023,006
JBrowse link
G CD79B CD79b molecule ISO protein:decreased expression:bone marrow, mononuclear cell (human) RGD PMID:21487112 RGD:11250414 NCBI chr 9:11,834,230...11,844,946
Ensembl chr 9:11,842,190...11,844,843
JBrowse link
G CD86 CD86 molecule severity ISO protein:increased expression:peripheral blood, bone marrow, mononuclear cell (human) RGD PMID:24283754 RGD:11354967 NCBI chr33:25,256,267...25,318,855
Ensembl chr33:25,256,267...25,318,087
JBrowse link
G CDK6 cyclin dependent kinase 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24736461 NCBI chr14:18,178,352...18,413,869
Ensembl chr14:18,188,429...18,419,869
JBrowse link
G CEBPE CCAAT enhancer binding protein epsilon ISO CTD Direct Evidence: marker/mechanism CTD PMID:19684604 NCBI chr 8:3,423,046...3,425,595
Ensembl chr 8:3,423,040...3,425,217
JBrowse link
G CFB complement factor B ISO DNA:missense mutation:p.R32Q b(human) RGD PMID:6958349 RGD:11041155 NCBI chr12:1,400,143...1,406,267 JBrowse link
G CREBBP CREB binding protein disease_progression ISO DNA:mutations:multiple RGD PMID:25917266 RGD:11060149 NCBI chr 6:37,410,201...37,536,688
Ensembl chr 6:37,409,930...37,534,176
JBrowse link
G CRLF2 cytokine receptor like factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19838194 NCBI chr  X:780,924...801,961
Ensembl chr  X:780,711...802,836
JBrowse link
G CSF3 colony stimulating factor 3 treatment ISO RGD PMID:9250830 RGD:11039038 NCBI chr 9:22,529,643...22,532,326
Ensembl chr 9:22,530,698...22,533,108
JBrowse link
G CSPG4 chondroitin sulfate proteoglycan 4 severity ISO RGD PMID:8562939 RGD:734840 NCBI chr30:38,465,486...38,498,365
Ensembl chr30:38,465,241...38,497,971
JBrowse link
G CYBA cytochrome b-245 alpha chain ISO mRNA:increased expression:peripheral blood mononuclear cell: RGD PMID:19222940 RGD:11040545 NCBI chr 5:64,692,865...64,701,056
Ensembl chr 5:64,692,123...64,704,893
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 no_association
susceptibility
ISO DNA:polymorphism:3'UTR:3801T>C(human)
DNA:polymorphism:cds:2452C>A(p.T461N)(human)
DNA:polymorphism:3"UTR:rs4646903(human)
RGD PMID:16676594 PMID:22964275 PMID:23725389 RGD:11352714 RGD:11352725 RGD:11352728 NCBI chr30:37,793,277...37,799,535
Ensembl chr30:37,793,508...37,796,866
JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22674224 NCBI chr30:37,818,400...37,824,192
Ensembl chr30:37,799,140...37,824,135
JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22674224 NCBI chr17:30,273,281...30,278,554
Ensembl chr17:30,272,749...30,278,554
JBrowse link
G CYP2D15 cytochrome P450 family 2 subfamily D member 15 susceptibility ISO DNA:polymorphisms: :
DNA:SNP,deletion:splice junction,exon:1934G>A(human)
RGD PMID:11037802 PMID:19593802 RGD:11252111 RGD:11352820 NCBI chr10:23,255,259...23,259,380
Ensembl chr10:23,255,249...23,259,298
JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11774269 NCBI chr28:41,079,164...41,089,188
Ensembl chr28:41,035,025...41,122,754
JBrowse link
G DNMT3A DNA methyltransferase 3 alpha treatment ISO DNA:mutations:exon, intron:p.R882(human) RGD PMID:25242092 RGD:11041125 NCBI chr17:19,489,524...19,563,074
Ensembl chr17:19,492,193...19,563,902
JBrowse link
G DNTT DNA nucleotidylexotransferase ISO protein:increased activity:peripheral blood,bone marrow: RGD PMID:7020399 RGD:8694149 NCBI chr28:9,729,812...9,759,019
Ensembl chr28:9,729,814...9,759,008
JBrowse link
G DPYD dihydropyrimidine dehydrogenase disease_progression
no_association
ISO DNA:splice-site mutation:intron:IVS14+1G>A (human)
DNA:SNPs: :2194G>A, 1156G>T (human)
DNA:SNP: :85T>C (human)
RGD PMID:26846104 RGD:11098453 NCBI chr 6:51,789,786...52,564,802
Ensembl chr 6:51,814,573...52,580,923
JBrowse link
G ENG endoglin disease_progression ISO RGD PMID:17572488 RGD:11041565 NCBI chr 9:55,558,246...55,590,081
Ensembl chr 9:55,558,305...55,589,064
JBrowse link
G EPHX1 epoxide hydrolase 1 susceptibility
no_association
ISO DNA:polymorphisms:exon
DNA:SNPs:exon:rs1051740, rs2234922 (human)
DNA:missense mutation, haplotype:exon:p.H139R (human)
CTD Direct Evidence: marker/mechanism
DNA:missense mutation, haplotype:exon:p.Y113H (human)
RGD
CTD
PMID:19593802 PMID:21983886 PMID:22200898 PMID:22930568 RGD:11252110 RGD:11252111 RGD:11252113 RGD:11252114 NCBI chr 7:38,964,319...39,004,902
Ensembl chr 7:38,964,338...38,999,238
JBrowse link
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit susceptibility ISO DNA:SNPs, haplotypes: :p.R194W, p.R280H, p.R399Q (human)
DNA:SNPs: :8092C>A, 19007G>A (human)
RGD PMID:16435384 PMID:16723154 RGD:11252160 RGD:11340204 NCBI chr 1:110,130,353...110,146,660
Ensembl chr 1:110,130,481...110,146,602
JBrowse link
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit no_association ISO DNA:missense mutations: :p.D312N, p.K751Q (human)
DNA:haplotype
RGD PMID:19101034 PMID:21987080 RGD:11252192 RGD:11340201 NCBI chr 1:110,173,781...110,191,612
Ensembl chr 1:110,173,715...110,190,125
JBrowse link
G ERG ETS transcription factor ERG ISO CTD Direct Evidence: marker/mechanism CTD PMID:27776115 NCBI chr31:33,456,902...33,562,704
Ensembl chr31:33,497,209...33,515,272
JBrowse link
G ETV6 ETS variant transcription factor 6 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Acute lymphoid leukemia
CTD
ClinVar
PMID:17255265 NCBI chr27:34,351,206...34,587,060
Ensembl chr27:34,343,390...34,587,060
JBrowse link
G F3 coagulation factor III, tissue factor ISO RGD PMID:8429686 RGD:11340211 NCBI chr 6:54,709,581...54,720,603
Ensembl chr 6:54,708,471...54,720,607
JBrowse link
G FAS Fas cell surface death receptor disease_progression ISO protein:increased expression:CD34+ bone marrow cell RGD PMID:9711907 PMID:10500800 RGD:11049148 RGD:11049157 NCBI chr26:38,738,811...38,763,298
Ensembl chr26:38,737,611...38,763,321
JBrowse link
G FGA fibrinogen alpha chain ISO protein:increased expression:serum (human) RGD PMID:25317080 RGD:11040558 NCBI chr15:52,238,305...52,247,017
Ensembl chr15:52,236,198...52,246,975
JBrowse link
G FLT3 fms related receptor tyrosine kinase 3 susceptibility ISO ClinVar Annotator: match by term: Acute lymphocytic leukemia
CTD Direct Evidence: marker/mechanism
OMIM
ClinVar
CTD
PMID:11290608 PMID:11442493 PMID:14604974 PMID:14670924 PMID:15256420 PMID:16857985 PMID:17606455 PMID:17889720 PMID:19657110 PMID:20733134 PMID:22368270 PMID:22504183 PMID:22504184 PMID:23261068 PMID:23321257 PMID:23430109 PMID:23714533 PMID:23783394 PMID:24046014 PMID:25157968 NCBI chr25:11,551,372...11,670,891
Ensembl chr25:11,581,206...11,692,284
JBrowse link
G FPGS folylpolyglutamate synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25013492 NCBI chr 9:55,590,092...55,612,639
Ensembl chr 9:55,585,970...55,599,028
JBrowse link
G GFI1B growth factor independent 1B transcriptional repressor ISO mRNA:increased expression:blood: RGD PMID:19360458 RGD:11040460 NCBI chr 9:51,380,697...51,394,679
Ensembl chr 9:51,380,696...51,392,812
JBrowse link
G GNB1 G protein subunit beta 1 susceptibility ISO ClinVar Annotator: match by term: Acute lymphoid leukemia
CTD Direct Evidence: marker/mechanism
OMIM
ClinVar
CTD
PMID:25485910 PMID:27108799 NCBI chr 5:56,777,854...56,879,619
Ensembl chr 5:56,779,354...56,817,295
JBrowse link
G GPI glucose-6-phosphate isomerase ISO RGD PMID:6589021 RGD:11051848 NCBI chr 1:117,922,380...117,948,325
Ensembl chr 1:117,922,635...117,948,316
JBrowse link
G GPX1 glutathione peroxidase 1 treatment ISO RGD PMID:17317918 PMID:24698347 RGD:11352774 RGD:11352812 NCBI chr20:39,889,165...39,890,253
Ensembl chr20:39,889,174...39,890,260
JBrowse link
G GSR glutathione-disulfide reductase ISO RGD PMID:24191316 RGD:11059506 NCBI chr16:33,633,949...33,680,411
Ensembl chr16:33,633,968...33,679,752
JBrowse link
G GSTP1 glutathione S-transferase pi 1 disease_progression
susceptibility
no_association
ISO DNA:haplotype:cds:
DNA:transition mutation:exon:
DNA:polymorphism: :1578 a>G(human)
RGD PMID:10666194 PMID:15738600 PMID:23979883 RGD:10450829 RGD:10755321 RGD:10755417 NCBI chr18:49,905,161...49,908,182
Ensembl chr18:49,905,161...49,908,182
JBrowse link
G H1-2 H1.2 linker histone, cluster member susceptibility ISO DNA:SNP, haplotype:enhancer: (rs807212) (human) RGD PMID:19806355 RGD:10755490 NCBI chr35:24,009,304...24,011,602 JBrowse link
G HCK HCK proto-oncogene, Src family tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:17344919 NCBI chr24:21,473,424...21,513,673
Ensembl chr24:21,473,305...21,513,564
JBrowse link
G HDAC1 histone deacetylase 1 disease_progression ISO mRNA:increased expression:bone marrow,blood: RGD PMID:23948281 RGD:9681454 NCBI chr 2:68,901,339...68,936,473
Ensembl chr 2:68,901,651...68,936,186
JBrowse link
G HDAC2 histone deacetylase 2 disease_progression ISO mRNA:increased expression:bone marrow,blood: RGD PMID:23948281 RGD:9681454 NCBI chr12:70,053,822...70,083,491
Ensembl chr12:70,053,297...70,103,578
JBrowse link
G HDAC4 histone deacetylase 4 treatment ISO RGD PMID:23948281 RGD:9681454 NCBI chr25:49,318,621...49,545,314
Ensembl chr25:49,317,349...49,453,478
JBrowse link
G HFE homeostatic iron regulator no_association ISO DNA:missense mutation:cds:p.C282Y (human)
DNA:missense mutation: :p.H63D (human)
DNA:missense mutation:cds:p.H63D (human)
RGD PMID:10627122 PMID:17107905 RGD:10755557 RGD:10755558 NCBI chr35:24,031,479...24,038,922
Ensembl chr35:24,031,387...24,042,413
JBrowse link
G HK1 hexokinase 1 ISO protein:decreased activity:platelet RGD PMID:21921332 RGD:11353881 NCBI chr 4:20,396,761...20,516,889
Ensembl chr 4:20,421,526...20,518,211
JBrowse link
G HLF HLF transcription factor, PAR bZIP family member ISO CTD Direct Evidence: marker/mechanism CTD PMID:26214592 NCBI chr 9:30,321,090...30,380,480
Ensembl chr 9:30,327,495...30,377,175
JBrowse link
G HOXD4 homeobox D4 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Leukemia, acute lymphoblastic, susceptibility to
CTD
ClinVar
PMID:15776434
G IDH1 isocitrate dehydrogenase (NADP(+)) 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22674224 NCBI chr37:16,512,027...16,531,269
Ensembl chr37:16,512,770...16,531,219
JBrowse link
G IFNG interferon gamma susceptibility ISO DNA:SNP: :rs2069727(human) RGD PMID:21067287 RGD:10755691 NCBI chr10:10,406,866...10,411,698
Ensembl chr10:10,406,867...10,411,698
JBrowse link
G IKZF1 IKAROS family zinc finger 1 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: LEUKEMIA, ACUTE LYMPHOCYTIC, SUSCEPTIBILITY TO, 2
CTD
ClinVar
PMID:19684604 NCBI chr18:1,661,851...1,750,987
Ensembl chr18:1,661,690...1,770,768
JBrowse link
G IKZF2 IKAROS family zinc finger 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23334668 NCBI chr37:20,508,647...20,662,549
Ensembl chr37:20,516,239...20,661,298
JBrowse link
G IKZF3 IKAROS family zinc finger 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23334668 NCBI chr 9:22,643,482...22,733,988
Ensembl chr 9:22,643,640...22,728,385
JBrowse link
G IL10 interleukin 10 treatment ISO protein:decreased expression:blood RGD PMID:15860861 PMID:21653647 RGD:11049158 RGD:11049169 NCBI chr 7:5,933,285...5,937,057
Ensembl chr 7:5,933,285...5,937,057
JBrowse link
G IRF4 interferon regulatory factor 4 ISO DNA:SNP:intron:rs12203592 (human) RGD PMID:19897031 RGD:11526162 NCBI chr35:760,367...782,314
Ensembl chr35:767,011...781,339
JBrowse link
G ITPA inosine triphosphatase treatment
no_association
ISO DNA:SNPs:exon:94C>A, 138G>A (human)
DNA:SNP:intron
RGD PMID:22009189 RGD:10766474 NCBI chr24:18,070,980...18,081,815
Ensembl chr24:18,064,983...18,082,163
JBrowse link
G KDM2B lysine demethylase 2B ISO mRNA:increased expression:bone marrow (human) RGD PMID:21310926 RGD:9588255 NCBI chr26:7,625,857...7,746,049
Ensembl chr26:7,598,931...7,745,113
JBrowse link
G KDM3B lysine demethylase 3B ISO protein:increased expression:bone marrow, mononuclear cell (human) RGD PMID:22615488 RGD:9586728 NCBI chr11:25,954,352...26,024,919
Ensembl chr11:25,943,864...26,023,866
JBrowse link
G KDM6A lysine demethylase 6A severity ISO DNA:mutations:cds:multiple (human) RGD PMID:22377896 RGD:9684944 NCBI chr  X:38,745,854...38,964,029
Ensembl chr  X:38,745,854...38,959,842
JBrowse link
G KMT2A lysine methyltransferase 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:24736461 PMID:25730765 NCBI chr 5:15,212,559...15,302,825
Ensembl chr 5:15,217,348...15,270,971
JBrowse link
G KRAS KRAS proto-oncogene, GTPase disease_progression ISO RGD PMID:17910045 PMID:25917266 RGD:11060148 RGD:11060149 NCBI chr27:22,261,753...22,296,704
Ensembl chr27:22,257,941...22,293,369
JBrowse link
G LOC100683783 double homeobox protein 4C-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:27776115 NCBI chr17:64,277,421...64,282,701 JBrowse link
G LOC486411 immunoglobulin iota chain-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:26214592 NCBI chr26:28,833,763...28,834,870
Ensembl chr26:28,833,136...28,834,679
JBrowse link
G LOC609365 CD46 molecule, complement regulatory protein-like ISO protein:increased expression:peripheral blood mononuclear cell (human) RGD PMID:16353080 RGD:11352810 NCBI chr 7:6,602,762...6,646,561 JBrowse link
G MEFV MEFV innate immuity regulator, pyrin susceptibility ISO DNA:polymorphisms:cds:p.E148Q,M680I(human) RGD PMID:22942567 RGD:11531121 NCBI chr 6:37,964,776...37,984,830
Ensembl chr 6:37,970,608...37,983,737
JBrowse link
G MTHFR methylenetetrahydrofolate reductase treatment
disease_progression
ISO CTD Direct Evidence: marker/mechanism
DNA:missense mutation:cds:677C>T (human)
DNA:missense mutation:cds:677C>T (p.A222V) (rs1801133) (human)
CTD
RGD
PMID:16706930 PMID:19923983 PMID:21644011 RGD:10449398 RGD:10449407 NCBI chr 2:84,445,526...84,457,435
Ensembl chr 2:84,380,919...84,536,818
JBrowse link
G MTR 5-methyltetrahydrofolate-homocysteine methyltransferase no_association
disease_progression
susceptibility
ISO DNA:polymorphism: :2756A>G(human)
DNA:SNP::rs10925235(human)
DNA:polymorphism: :66A>G(human)
RGD PMID:15159311 PMID:21618417 PMID:22453148 PMID:26605150 RGD:11531136 RGD:11531137 RGD:11531140 RGD:11531141 NCBI chr 4:3,219,851...3,328,000
Ensembl chr 4:3,215,090...3,328,115
JBrowse link
G MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase susceptibility ISO DNA:SNP: :rs3776455(human)
CTD Direct Evidence: marker/mechanism
DNA:haplotype:cds:
RGD
CTD
PMID:17136115 PMID:23940529 RGD:11531133 RGD:11531135 NCBI chr34:6,068,572...6,119,580
Ensembl chr34:6,070,046...6,098,312
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor disease_progression ISO RGD PMID:25784651 RGD:11532748 NCBI chr13:25,200,772...25,205,309
Ensembl chr13:25,200,577...25,205,309
JBrowse link
G NBN nibrin susceptibility ISO ClinVar Annotator: match by term: Leukemia, acute lymphoblastic, susceptibility to
ClinVar Annotator: match by term: Acute lymphoid leukemia
CTD Direct Evidence: marker/mechanism
OMIM
ClinVar
CTD
PMID:11325820 PMID:14559852 PMID:15338273 PMID:16474176 PMID:16810201 PMID:17695489 PMID:17894553 PMID:17899368 PMID:18049891 PMID:18280732 PMID:19393249 PMID:19452044 PMID:19523210 PMID:19813148 PMID:19908051 PMID:21212067 PMID:21698754 PMID:22131123 PMID:22373003 PMID:23317186 PMID:23555315 PMID:24093751 PMID:24113799 PMID:24549055 PMID:24728327 PMID:24830725 PMID:25619955 PMID:25712764 PMID:25741868 PMID:26083025 PMID:26315354 PMID:26467025 PMID:26722329 PMID:27153395 PMID:27616075 PMID:27621404 PMID:28076423 PMID:28261280 PMID:28376765 PMID:28492532 PMID:28591191 PMID:29335925 PMID:29678143 PMID:29785153 PMID:30287823 PMID:30441849 PMID:30590007 PMID:30651582 PMID:31159747 PMID:32566746 NCBI chr29:35,416,093...35,477,569
Ensembl chr29:35,416,093...35,477,563
JBrowse link
G NOS3 nitric oxide synthase 3 susceptibility
disease_progression
ISO DNA:SNP: :rs3918186(human)
DNA:polymorphism, haplotype:cds,intron:P.E298D,-786T>C(human)
RGD PMID:20510681 PMID:23922896 RGD:11533639 RGD:11533646 NCBI chr16:15,054,196...15,072,454
Ensembl chr16:15,011,344...15,072,277
JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 ISO DNA:missense mutations: :p.R139W (465C>T), p.P187S (609C>T) (human)
DNA:mutation: :609C>T (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:11774269 PMID:17332311 PMID:18444911 RGD:10769347 RGD:10769359 NCBI chr 5:79,979,593...79,990,875
Ensembl chr 5:79,978,865...79,989,860
JBrowse link
G NRAS NRAS proto-oncogene, GTPase disease_progression ISO DNA:missense mutation:cds: RGD PMID:25204082 RGD:11535045 NCBI chr17:52,411,733...52,418,788
Ensembl chr17:52,411,733...52,418,788
JBrowse link
G NSD2 nuclear receptor binding SET domain protein 2 ISO CTD Direct Evidence: therapeutic CTD PMID:24076604 NCBI chr 3:62,164,888...62,228,006
Ensembl chr 3:62,167,939...62,228,035
JBrowse link
G NT5C2 5'-nucleotidase, cytosolic II ISO CTD Direct Evidence: marker/mechanism CTD PMID:23377183 NCBI chr28:15,525,581...15,621,287
Ensembl chr28:15,526,790...15,621,235
JBrowse link
G NUP214 nucleoporin 214 susceptibility ISO CTD Direct Evidence: marker/mechanism OMIM
CTD
NCBI chr 9:52,840,300...52,943,785
Ensembl chr 9:52,841,096...52,947,770
JBrowse link
G P2RY8 P2Y receptor family member 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19838194 NCBI chr  X:1,060,204...1,097,471 JBrowse link
G PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23334668 NCBI chr29:28,207,445...28,340,812
Ensembl chr29:28,211,031...28,263,322
JBrowse link
G PAX5 paired box 5 susceptibility ISO ClinVar Annotator: match by term: Leukemia, acute lymphoblastic, susceptibility to, 3
ClinVar Annotator: match by term: Acute lymphoid leukemia
CTD Direct Evidence: marker/mechanism
OMIM
ClinVar
CTD
PMID:24013638 PMID:25741868 PMID:26214592 NCBI chr11:53,194,905...53,390,204
Ensembl chr11:53,201,344...53,390,974
JBrowse link
G PON1 paraoxonase 1 susceptibility ISO DNA:missense mutations:cds:p.L55M (rs854560), p.Q192R (rs662) (human) RGD PMID:22976839 RGD:11552580 NCBI chr14:20,565,620...20,600,774
Ensembl chr14:20,565,641...20,642,985
JBrowse link
G PRAME PRAME nuclear receptor transcriptional regulator severity ISO mRNA:increased expression:blood (human) RGD PMID:27275197 RGD:11535025 NCBI chr26:27,124,901...27,137,772
Ensembl chr26:27,124,902...27,136,112
JBrowse link
G PRDM14 PR/SET domain 14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19043588 NCBI chr29:19,203,798...19,220,149
Ensembl chr29:19,203,807...19,220,518
JBrowse link
G RB1 RB transcriptional corepressor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23334668 NCBI chr22:3,061,621...3,204,625
Ensembl chr22:3,063,239...3,257,726
JBrowse link
G RUNX1 RUNX family transcription factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17255265 NCBI chr31:30,170,859...30,420,344
Ensembl chr31:30,170,605...30,420,839
JBrowse link
G SLC19A1 solute carrier family 19 member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17255265 NCBI chr31:38,958,332...38,971,091
Ensembl chr31:38,967,013...38,971,094
JBrowse link
G SNRPE small nuclear ribonucleoprotein polypeptide E severity ISO mRNA:decreased expression:bone marrow, blood, mononuclear cell (human) RGD PMID:23915977 RGD:10768836 NCBI chr38:515,808...521,536
Ensembl chr38:515,860...521,535
JBrowse link
G TAL1 TAL bHLH transcription factor 1, erythroid differentiation factor susceptibility ISO CTD Direct Evidence: marker/mechanism OMIM
CTD
NCBI chr15:13,446,752...13,462,038
Ensembl chr15:13,449,481...13,462,047
JBrowse link
G TAL2 TAL bHLH transcription factor 2 susceptibility ISO CTD Direct Evidence: marker/mechanism OMIM
CTD
NCBI chr11:61,425,927...61,484,525
Ensembl chr11:61,456,727...61,482,348
JBrowse link
G TCF3 transcription factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26214592 NCBI chr20:57,255,091...57,284,223
Ensembl chr20:57,254,384...57,283,981
JBrowse link
G TCN2 transcobalamin 2 ISO protein:altered activity:plasma: RGD PMID:8754152 RGD:11059889 NCBI chr26:23,693,664...23,710,342
Ensembl chr26:23,693,773...23,709,832
JBrowse link
G TERT telomerase reverse transcriptase ISO DNA:SNPs:promoter, introns:g.1296486C>T, g.12866516A>C, g.1279790G>A (rs2735940, rs2736100, rs10069690) (human) RGD PMID:15621763 PMID:23066086 RGD:11038654 RGD:11038667 NCBI chr34:11,288,622...11,307,790
Ensembl chr34:11,288,622...11,307,951
JBrowse link
G TM9SF2 transmembrane 9 superfamily member 2 ISO mRNA:increased expression:bone marrow, mononuclear cells (human) RGD PMID:12730115 RGD:2317244 NCBI chr22:49,515,350...49,578,519
Ensembl chr22:49,515,382...49,577,905
JBrowse link
G TP53 tumor protein p53 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23334668 NCBI chr 5:32,561,406...32,565,149
Ensembl chr 5:32,560,598...32,574,109
JBrowse link
G TPMT thiopurine S-methyltransferase treatment
no_association
ISO DNA:SNPs:multiple
DNA:SNPs:introns:12356C>T, 16638C>T, 26354G>T (rs4449636, rs2518463, rs2842949) (human)
DNA:SNPs: :multiple
DNA:SNPs:exon:374C>T, 719A>G (rs2842934, rs1142345) (human)
RGD PMID:17164697 PMID:22009189 PMID:24499706 RGD:10766474 RGD:11038720 RGD:11038723 NCBI chr35:16,928,991...16,953,891
Ensembl chr35:16,929,240...16,953,229
JBrowse link
G TYMS thymidylate synthetase treatment ISO DNA:repeats: : rs347430033(human) RGD PMID:25007187 RGD:11080979 NCBI chr 7:67,487,927...67,497,747
Ensembl chr 7:67,487,927...67,497,747
JBrowse link
G XRCC1 X-ray repair cross complementing 1 susceptibility
no_association
ISO DNA:missense mutation: :p.R194W (human)
DNA:missense mutation, haplotype: :p.R399Q (human)
DNA:missense mutation: :p.R399Q (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:19101034 PMID:21983886 RGD:11252110 RGD:11252192 NCBI chr 1:111,548,719...111,571,816
Ensembl chr 1:111,548,719...111,571,816
JBrowse link
Acute Lymphoblastic Leukemia, with Lymphomatous Features term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase ISO ClinVar Annotator: match by term: Lymphoblastic leukemia, acute, with lymphomatous features ClinVar PMID:10988075 PMID:11423618 PMID:11853795 PMID:11861307 PMID:11964322 PMID:12130516 PMID:12399961 PMID:12623848 PMID:14559829 PMID:14745431 PMID:15194504 PMID:15256422 PMID:15381060 PMID:18615627 PMID:19466505 PMID:19652056 PMID:20367437 PMID:20512393 PMID:20537386 PMID:20697894 PMID:20963643 PMID:21505103 PMID:21562040 PMID:21762985 PMID:21872826 PMID:21895409 PMID:22306673 PMID:22772060 PMID:22870928 PMID:23355941 PMID:23540562 PMID:23676790 PMID:24236021 PMID:24456693 PMID:25157968 PMID:25686603 NCBI chr 9:53,118,462...53,262,092
Ensembl chr 9:53,119,641...53,261,307
JBrowse link
G CRLF2 cytokine receptor like factor 2 ISO ClinVar Annotator: match by term: Lymphoblastic leukemia, acute, with lymphomatous features ClinVar PMID:19907440 PMID:19965641 PMID:20018760 PMID:22368272 NCBI chr  X:780,924...801,961
Ensembl chr  X:780,711...802,836
JBrowse link
G CYP2B6 cytochrome P450 2B11 susceptibility ISO DNA:polymorphism:G15631T RGD PMID:19144407 RGD:6480472 NCBI chr 1:112,817,561...112,833,294
Ensembl chr 1:112,816,502...112,833,293
JBrowse link
G FGFR1 fibroblast growth factor receptor 1 ISO ClinVar Annotator: match by term: Lymphoblastic leukemia, acute, with lymphomatous features ClinVar PMID:25705862 PMID:26619011 PMID:26942290 NCBI chr16:27,029,902...27,080,514
Ensembl chr16:27,031,588...27,078,261
JBrowse link
G IL7R interleukin 7 receptor ISO ClinVar Annotator: match by term: Lymphoblastic leukemia, acute, with lymphomatous features ClinVar PMID:22897847 PMID:22955920 NCBI chr 4:72,633,528...72,668,242
Ensembl chr 4:72,636,325...72,668,300
JBrowse link
G INSL6 insulin like 6 ISO ClinVar Annotator: match by term: Lymphoblastic leukemia, acute, with lymphomatous features ClinVar PMID:18805579 PMID:19470474 PMID:20585391 PMID:22368270 PMID:22955920 NCBI chr 1:93,457,854...93,474,777
Ensembl chr 1:93,459,945...93,474,793
JBrowse link
G JAK1 Janus kinase 1 ISO ClinVar Annotator: match by term: Lymphoblastic leukemia, acute, with lymphomatous features ClinVar PMID:16239216 PMID:19139102 PMID:19470474 PMID:19838194 PMID:20167706 PMID:21436584 PMID:21680795 PMID:22955920 PMID:25356970 PMID:28111307 NCBI chr 5:45,251,653...45,408,571
Ensembl chr 5:45,251,653...45,408,571
JBrowse link
G JAK2 Janus kinase 2 ISO ClinVar Annotator: match by term: Lymphoblastic leukemia, acute, with lymphomatous features ClinVar PMID:18805579 PMID:19470474 PMID:20585391 PMID:22368270 PMID:22955920 NCBI chr 1:93,321,055...93,438,898
Ensembl chr 1:93,142,635...93,435,997
JBrowse link
G JAK3 Janus kinase 3 ISO ClinVar Annotator: match by term: Lymphoblastic leukemia, acute, with lymphomatous features ClinVar PMID:10982185 PMID:16843266 PMID:18270328 PMID:20132407 PMID:20372971 PMID:21599579 PMID:21821710 PMID:24728327 PMID:25157968 PMID:28492532 NCBI chr20:45,051,135...45,068,445
Ensembl chr20:45,050,526...45,072,805
JBrowse link
acute megakaryocytic leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCG2 ATP binding cassette subfamily G member 2 ISO RGD PMID:21640380 RGD:11081147 NCBI chr32:11,443,778...11,517,674
Ensembl chr32:11,443,780...11,517,674
JBrowse link
G APC APC regulator of WNT signaling pathway ISO ClinVar Annotator: match by term: Acute megakaryoblastic leukemia ClinVar PMID:25741868 PMID:28492532 NCBI chr 3:252,052...380,506
Ensembl chr 3:253,081...322,993
JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 ISO CTD Direct Evidence: therapeutic CTD PMID:16166298 NCBI chr 9:2,930,308...2,959,307 JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit ISO associated with Down Syndrome;DNA:mutations:multiple (human) RGD PMID:24056718 RGD:10450890 NCBI chr16:1,926,443...1,991,995
Ensembl chr16:1,925,956...1,991,838
JBrowse link
G GATA1 GATA binding protein 1 ISO ClinVar Annotator: match by term: Acute megakaryoblastic leukemia ClinVar PMID:15070711 NCBI chr  X:41,991,321...41,998,319
Ensembl chr  X:41,971,582...41,998,303
JBrowse link
G GFI1B growth factor independent 1B transcriptional repressor ISO mRNA:increased expression:bone marrow cell: RGD PMID:17156408 RGD:11040507 NCBI chr 9:51,380,697...51,394,679
Ensembl chr 9:51,380,696...51,392,812
JBrowse link
G JAK3 Janus kinase 3 ISO ClinVar Annotator: match by term: Acute megakaryoblastic leukemia RGD
ClinVar
PMID:10982185 PMID:16843266 PMID:18270328 PMID:18397343 PMID:20132407 PMID:20372971 PMID:20385788 PMID:20400977 PMID:21599579 PMID:21821710 PMID:22271575 PMID:24728327 PMID:25157968 PMID:28492532 RGD:11531113 NCBI chr20:45,051,135...45,068,445
Ensembl chr20:45,050,526...45,072,805
JBrowse link
G LOC102152446 coronin-7 ISO ClinVar Annotator: match by term: Acute megakaryoblastic leukemia ClinVar NCBI chr 6:36,980,302...37,038,210 JBrowse link
G MDGA1 MAM domain containing glycosylphosphatidylinositol anchor 1 ISO ClinVar Annotator: match by term: Acute megakaryoblastic leukemia ClinVar NCBI chr12:6,655,586...6,716,619
Ensembl chr12:6,659,910...6,686,760
JBrowse link
G MRTFA myocardin related transcription factor A ISO RGD PMID:11431691 RGD:1599948 NCBI chr10:24,561,161...24,759,586
Ensembl chr10:24,561,161...24,759,081
JBrowse link
G MT-ND6 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 ISO ClinVar Annotator: match by term: Acute megakaryoblastic leukemia ClinVar NCBI chr MT:13,582...14,109
Ensembl chr MT:13,582...14,109
JBrowse link
G PCF11 PCF11 cleavage and polyadenylation factor subunit ISO ClinVar Annotator: match by term: Acute megakaryoblastic leukemia ClinVar NCBI chr21:16,006,022...16,028,369
Ensembl chr21:16,006,749...16,028,021
JBrowse link
G PRAME PRAME nuclear receptor transcriptional regulator ISO associated with Down Syndrome;mRNA:increased expression:mononuclear cell (human) RGD PMID:15180862 RGD:11535064 NCBI chr26:27,124,901...27,137,772
Ensembl chr26:27,124,902...27,136,112
JBrowse link
G PTEN phosphatase and tensin homolog ISO ClinVar Annotator: match by term: Acute megakaryoblastic leukemia ClinVar PMID:10848731 PMID:17941496 PMID:20600018 PMID:21194675 PMID:21343951 PMID:21659347 PMID:22281088 PMID:22520842 PMID:23335809 PMID:23475934 PMID:23886400 PMID:24778394 PMID:26376867 PMID:28492532 PMID:29663862 NCBI chr26:37,853,148...37,913,176
Ensembl chr26:37,835,661...37,913,176
JBrowse link
G RASAL3 RAS protein activator like 3 ISO ClinVar Annotator: match by term: Acute megakaryoblastic leukemia ClinVar NCBI chr20:46,733,072...46,743,657
Ensembl chr20:46,732,952...46,743,924
JBrowse link
G RUNX1 RUNX family transcription factor 1 onset ISO RGD PMID:15856017 RGD:11251701 NCBI chr31:30,170,859...30,420,344
Ensembl chr31:30,170,605...30,420,839
JBrowse link
G SLC9A2 solute carrier family 9 member A2 ISO ClinVar Annotator: match by term: Acute megakaryoblastic leukemia ClinVar NCBI chr10:40,334,417...40,394,438
Ensembl chr10:40,338,284...40,394,470
JBrowse link
G SNCB synuclein beta ISO RGD PMID:21264917 RGD:6478703 NCBI chr 4:36,710,236...36,719,455
Ensembl chr 4:36,616,039...36,764,501
JBrowse link
G TP53 tumor protein p53 ISO ClinVar Annotator: match by term: Acute megakaryoblastic leukemia ClinVar NCBI chr 5:32,561,406...32,565,149
Ensembl chr 5:32,560,598...32,574,109
JBrowse link
acute monocytic leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNMT3A DNA methyltransferase 3 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:21399634 NCBI chr17:19,489,524...19,563,074
Ensembl chr17:19,492,193...19,563,902
JBrowse link
G KMT2A lysine methyltransferase 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:8282816 NCBI chr 5:15,212,559...15,302,825
Ensembl chr 5:15,217,348...15,270,971
JBrowse link
G MLLT10 MLLT10 histone lysine methyltransferase DOT1L cofactor ISO RGD PMID:7662954 RGD:1598771 NCBI chr 2:11,349,864...11,607,194
Ensembl chr 2:11,349,856...11,596,398
JBrowse link
G NF1 neurofibromin 1 ISO ClinVar Annotator: match by term: Acute monocytic leukemia ClinVar PMID:23407919 PMID:25741868 PMID:28492532 NCBI chr 9:41,467,460...41,679,388
Ensembl chr 9:41,469,416...41,679,382
JBrowse link
G STK11 serine/threonine kinase 11 ISO ClinVar Annotator: match by term: Acute monocytic leukemia ClinVar PMID:25117502 PMID:25741868 PMID:25980754 PMID:26467025 PMID:28492532 NCBI chr20:57,558,966...57,579,163
Ensembl chr20:57,559,424...57,579,118
JBrowse link
acute myeloid leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC3 ATP binding cassette subfamily C member 3 disease_progression ISO RGD PMID:26512967 RGD:11081145 NCBI chr 9:26,551,953...26,596,330
Ensembl chr 9:26,551,268...26,595,646
JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 treatment
disease_progression
ISO RGD PMID:12145683 PMID:26512967 RGD:11081145 RGD:11099971 NCBI chr32:11,443,778...11,517,674
Ensembl chr32:11,443,780...11,517,674
JBrowse link
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase ISO DNA:translocation: : RGD PMID:12161353 RGD:10450603 NCBI chr 9:53,118,462...53,262,092
Ensembl chr 9:53,119,641...53,261,307
JBrowse link
G ACSL6 acyl-CoA synthetase long chain family member 6 ISO DNA:translocation: :t(5;12)(q31;p13) (human) RGD PMID:10502316 RGD:1599805 NCBI chr11:20,226,877...20,284,919
Ensembl chr11:20,227,268...20,285,631
JBrowse link
G ADCY7 adenylate cyclase 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18206229 NCBI chr 2:65,003,891...65,034,812
Ensembl chr 2:65,006,038...65,034,777
JBrowse link
G AGRN agrin ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 5:56,239,621...56,273,679
Ensembl chr 5:56,239,701...56,272,745
JBrowse link
G ALK ALK receptor tyrosine kinase ISO ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:25741868 PMID:28492532 NCBI chr17:23,010,308...23,688,841
Ensembl chr17:23,010,308...23,688,841
JBrowse link
G ANAPC2 anaphase promoting complex subunit 2 ISO mRNA:increased expression:blood (human) RGD PMID:26046517 RGD:11067888 NCBI chr 9:48,475,777...48,486,715
Ensembl chr 9:48,471,584...48,609,303
JBrowse link
G ANXA2 annexin A2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr30:25,176,845...25,210,244
Ensembl chr30:25,115,842...25,218,281
JBrowse link
G ANXA4 annexin A4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr10:68,418,678...68,466,181
Ensembl chr10:68,431,056...68,466,174
JBrowse link
G ANXA5 annexin A5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr19:18,419,936...18,450,088
Ensembl chr19:18,407,587...18,570,378
JBrowse link
G ANXA6 annexin A6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 4:58,091,186...58,140,102
Ensembl chr 4:58,091,251...58,139,372
JBrowse link
G AQP9 aquaporin 9 ISO CTD Direct Evidence: therapeutic CTD PMID:16968895 NCBI chr30:23,223,413...23,271,893
Ensembl chr30:23,225,331...23,269,076
JBrowse link
G ASMTL acetylserotonin O-methyltransferase like ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr  X:1,102,094...1,118,791
Ensembl chr  X:1,100,747...1,118,791
JBrowse link
G ASXL1 ASXL transcriptional regulator 1 disease_progression ISO DNA:mutations:exon: RGD PMID:20693432 RGD:11038706 NCBI chr24:21,725,126...21,804,745
Ensembl chr24:21,661,059...21,802,815
JBrowse link
G ASXL2 ASXL transcriptional regulator 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27798625 NCBI chr17:19,914,026...20,065,141
Ensembl chr17:19,895,568...20,044,691
JBrowse link
G ATG2B autophagy related 2B ISO ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar NCBI chr 8:65,039,960...65,110,811
Ensembl chr 8:65,044,194...65,110,796
JBrowse link
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 7:29,464,132...29,487,124
Ensembl chr 7:29,464,132...29,487,947
JBrowse link
G BAALC BAALC binder of MAP3K1 and KLF4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19822134 NCBI chr13:4,602,688...4,684,138
Ensembl chr13:4,603,020...4,682,189
JBrowse link
G BACH2 BTB domain and CNC homolog 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21441929 NCBI chr12:49,101,621...49,375,415
Ensembl chr12:49,106,523...49,460,286
JBrowse link
G BCL2 BCL2 apoptosis regulator severity
susceptibility
ISO CTD Direct Evidence: marker/mechanism
ratio with Flt3, Kit;mRNA:decreased expression:mononuclear cell (human)
DNA:snp:exon:c.+21A>G (rs1801018) (human)
DNA:snp:promoter:g.-938C>A (human)
CTD
RGD
PMID:19520430 PMID:23906301 PMID:25216797 PMID:25957891 RGD:11526107 RGD:11526109 RGD:11526111 NCBI chr 1:13,733,849...13,900,653
Ensembl chr 1:13,731,406...13,900,658
JBrowse link
G BCL2L1 BCL2 like 1 severity ISO mRNA:increased expression:peripheral blood, bone marrow, blast cell (human) RGD PMID:11410409 RGD:11353851 NCBI chr24:21,145,214...21,209,425
Ensembl chr24:21,145,215...21,196,355
JBrowse link
G BDKRB1 bradykinin receptor B1 ISO ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar NCBI chr 8:65,017,655...65,028,899 JBrowse link
G BDKRB2 bradykinin receptor B2 ISO ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar NCBI chr 8:64,974,588...65,005,682
Ensembl chr 8:64,974,997...65,003,407
JBrowse link
G BMI1 BMI1 proto-oncogene, polycomb ring finger ISO RGD PMID:16105758 RGD:1580059 NCBI chr 2:10,818,232...10,828,473
Ensembl chr 2:10,818,232...10,833,613
JBrowse link
G BRCA2 BRCA2 DNA repair associated ISO ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:15766593 PMID:25741868 PMID:26467025 PMID:28492532 PMID:29021639 NCBI chr25:7,734,450...7,797,851
Ensembl chr25:7,734,453...7,797,815
JBrowse link
G BRD4 bromodomain containing 4 ISO RGD PMID:21814200 RGD:9586350 NCBI chr20:46,844,795...46,927,620
Ensembl chr20:46,891,514...46,927,608
JBrowse link
G BRD7 bromodomain containing 7 susceptibility ISO DNA:haplotype:cds:737A>G,495C>T(human)
mRNA:increased expression:bone marrow:
RGD PMID:18772500 RGD:9586443 NCBI chr 2:64,966,636...65,002,800
Ensembl chr 2:64,966,392...65,002,799
JBrowse link
G BTG1 BTG anti-proliferation factor 1 disease_progression ISO RGD PMID:15449376 RGD:1549463 NCBI chr15:32,646,520...32,648,222
Ensembl chr15:32,647,472...32,647,762
JBrowse link
G C8H14orf132 chromosome 8 C14orf132 homolog ISO ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar NCBI chr 8:64,813,713...64,861,449
Ensembl chr 8:64,813,303...64,855,348
JBrowse link
G CALR calreticulin ISO mRNA:increased expression:peripheral blood (human) RGD PMID:26640226 RGD:11076986 NCBI chr20:49,251,390...49,255,291
Ensembl chr20:49,251,777...49,255,245
JBrowse link
G CAPG capping actin protein, gelsolin like ISO CTD Direct Evidence: marker/mechanism CTD PMID:18206229 NCBI chr17:39,619,429...39,640,944
Ensembl chr17:39,619,248...39,640,942
JBrowse link
G CAPN2 calpain 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 7:40,333,379...40,367,158
Ensembl chr 7:40,334,012...40,377,037
JBrowse link
G CASP7 caspase 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr28:24,599,866...24,630,018
Ensembl chr28:24,599,493...24,628,668
JBrowse link
G CBFB core-binding factor subunit beta ISO OMIM NCBI chr 5:82,253,496...82,313,765
Ensembl chr 5:82,255,617...82,313,168
JBrowse link
G CBL Cbl proto-oncogene disease_progression ISO associated with Myelodysplastic Syndromes;DNA:mutations:exons: RGD PMID:22131879 RGD:11038796 NCBI chr 5:14,600,409...14,676,974
Ensembl chr 5:14,607,013...14,676,956
JBrowse link
G CCL2 C-C motif chemokine ligand 2 treatment ISO protein:increased expression:plasma (human) RGD PMID:17822317 PMID:25382729 RGD:11528532 RGD:11528537 NCBI chr 9:39,008,187...39,009,932 JBrowse link
G CCNA1 cyclin A1 ISO protein:increased expression:leukocyte (human) RGD PMID:10068680 RGD:2316304 NCBI chr25:4,189,457...4,198,170
Ensembl chr25:4,189,457...4,198,373
JBrowse link
G CCND1 cyclin D1 treatment ISO human tumor in a mouse model
mRNA:increased expression:bone marrow (human)
RGD PMID:21928377 PMID:22391157 RGD:11352824 RGD:11353789 NCBI chr18:48,501,905...48,509,684
Ensembl chr18:48,501,899...48,516,005
JBrowse link
G CCND2 cyclin D2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27798625 NCBI chr27:40,563,306...40,593,362
Ensembl chr27:40,564,921...40,594,255
JBrowse link
G CD44 CD44 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:23098472 NCBI chr18:32,735,493...32,826,483
Ensembl chr18:32,737,907...32,827,107
JBrowse link
G CD86 CD86 molecule severity ISO protein:increased expression:mononuclear cell of bone marrow (human) RGD PMID:16115907 PMID:19197726 RGD:11354960 RGD:4892295 NCBI chr33:25,256,267...25,318,855
Ensembl chr33:25,256,267...25,318,087
JBrowse link
G CD9 CD9 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr27:38,742,539...38,754,984
Ensembl chr27:38,742,963...38,774,576
JBrowse link
G CDH1 cadherin 1 disease_progression ISO DNA:hypermethylation:promoter: RGD PMID:15863205 RGD:11252161 NCBI chr 5:80,757,508...80,834,878
Ensembl chr 5:80,757,508...80,834,878
JBrowse link
G CDK6 cyclin dependent kinase 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18206229 NCBI chr14:18,178,352...18,413,869
Ensembl chr14:18,188,429...18,419,869
JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B ISO DNA:deletion: : RGD PMID:9171997 RGD:10450601 NCBI chr27:33,609,154...33,613,558
Ensembl chr27:33,611,760...33,612,906
JBrowse link
G CDKN2B cyclin dependent kinase inhibitor 2B susceptibility
disease_progression
treatment
ISO DNA:hypermethylation: :
DNA:deletion: :
DNA:hypermethylation:promoter:
mRNA:decreased expression:granulocyte,monocyte:
RGD PMID:9001419 PMID:11064355 PMID:14681685 PMID:15863205 PMID:25616284 PMID:27168825 RGD:11251739 RGD:11251749 RGD:11252161 RGD:11252164 RGD:11252167 RGD:11252196 NCBI chr11:41,259,627...41,264,832 JBrowse link
G CEBPA CCAAT enhancer binding protein alpha ISO OMIM NCBI chr 1:118,846,252...118,851,045 JBrowse link
G CEBPD CCAAT enhancer binding protein delta ISO CTD Direct Evidence: marker/mechanism CTD PMID:17234736 NCBI chr35:74,994...77,816 JBrowse link
G CFLAR CASP8 and FADD like apoptosis regulator disease_progression ISO RGD PMID:23167276 RGD:11341679 NCBI chr37:10,268,407...10,307,803
Ensembl chr37:10,268,582...10,345,095
JBrowse link
G CHI3L1 chitinase 3 like 1 severity ISO protein:increased secretion:serum (human) RGD PMID:16361549 RGD:4892644 NCBI chr 7:25,620...32,954
Ensembl chr 7:26,316...33,427
JBrowse link
G CHIC2 cysteine rich hydrophobic domain 2 ISO OMIM NCBI chr13:46,558,657...46,606,226
Ensembl chr13:46,560,009...46,607,959
JBrowse link
G CHMP5 charged multivesicular body protein 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17708794 NCBI chr11:50,363,488...50,376,081 JBrowse link
G CNR2 cannabinoid receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15039279 NCBI chr 2:75,640,636...75,662,000
Ensembl chr 2:75,658,999...75,660,126
JBrowse link
G CREBBP CREB binding protein ISO DNA:translocations:intron:IVS2 (human) RGD PMID:12461753 RGD:734819 NCBI chr 6:37,410,201...37,536,688
Ensembl chr 6:37,409,930...37,534,176
JBrowse link
G CSF1R colony stimulating factor 1 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:1390197 NCBI chr 4:58,980,699...59,010,683
Ensembl chr 4:58,980,788...59,010,510
JBrowse link
G CSF2 colony stimulating factor 2 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:1826536 PMID:21441929 RGD:10449528 NCBI chr11:20,342,880...20,346,959
Ensembl chr11:20,344,648...20,346,959
JBrowse link
G CSF3 colony stimulating factor 3 treatment ISO CTD Direct Evidence: therapeutic RGD
CTD
PMID:7528855 PMID:10673519 RGD:11039033 NCBI chr 9:22,529,643...22,532,326
Ensembl chr 9:22,530,698...22,533,108
JBrowse link
G CSF3R colony stimulating factor 3 receptor susceptibility
disease_progression
ISO associated with Severe Congenital Neutropenia;DNA:nonsense mutation:cds:
ClinVar Annotator: match by term: Acute myelocytic leukemia
RGD
ClinVar
PMID:9001427 PMID:21911095 PMID:23604229 PMID:23634996 PMID:23656643 PMID:24081659 PMID:24403076 PMID:24614839 PMID:24746896 PMID:24854193 PMID:25491280 PMID:25741868 PMID:25932451 PMID:26875968 PMID:27148573 PMID:27581359 PMID:28209919 PMID:28219221 PMID:28492532 PMID:28762112 PMID:30967555 RGD:10450468 RGD:10450470 RGD:10450487 NCBI chr15:5,818,985...5,832,455
Ensembl chr15:5,822,025...5,831,882
JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 ISO DNA:SNP:3'UTR:rs3087243(human) RGD PMID:19092854 RGD:11344911 NCBI chr37:12,647,712...12,653,874
Ensembl chr37:12,634,563...12,653,874
JBrowse link
G CTNNA1 catenin alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr11:26,273,322...26,459,497
Ensembl chr11:26,143,013...26,459,091
JBrowse link
G CTSH cathepsin H ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 3:58,103,284...58,113,958
Ensembl chr 3:58,103,291...58,113,718
JBrowse link
G CTSZ cathepsin Z ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr24:43,743,291...43,750,154
Ensembl chr24:43,743,294...43,754,424
JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 treatment
disease_progression
ISO RGD PMID:24035716 PMID:26031918 RGD:11352265 RGD:11352273 NCBI chr19:38,874,650...38,877,740
Ensembl chr19:38,874,145...38,877,740
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 no_association
disease_progression
ISO DNA:SNP: :4889A>G (human)
DNA:polymorphism: :6235T>C (human)
DNA:SNP: :6235T>C (human)
RGD PMID:15996939 PMID:19456854 RGD:10769358 RGD:11352736 NCBI chr30:37,793,277...37,799,535
Ensembl chr30:37,793,508...37,796,866
JBrowse link
G CYP2B6 cytochrome P450 2B11 susceptibility ISO DNA:polymorphism:G15631T RGD PMID:19144407 RGD:6480472 NCBI chr 1:112,817,561...112,833,294
Ensembl chr 1:112,816,502...112,833,293
JBrowse link
G CYP2D15 cytochrome P450 family 2 subfamily D member 15 susceptibility
treatment
ISO DNA:polymorphisms: :
DNA:SNP: :(rs16947)(human)
RGD PMID:11037802 PMID:21518482 RGD:11352820 RGD:11352828 NCBI chr10:23,255,259...23,259,380
Ensembl chr10:23,255,249...23,259,298
JBrowse link
G DAPK1 death associated protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19874806 NCBI chr 1:72,278,939...72,448,907
Ensembl chr 1:72,280,103...72,447,822
JBrowse link
G DDX41 DEAD-box helicase 41 ISO ClinVar Annotator: match by term: Leukemia, acute myelogenous
ClinVar Annotator: match by term: Acute myeloid leukemia
ClinVar PMID:25741868 PMID:25920683 PMID:26712909 NCBI chr 4:35,854,382...35,859,853
Ensembl chr 4:35,854,597...35,859,852
JBrowse link
G DHX15 DEAH-box helicase 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27798625 PMID:29163777 NCBI chr 3:85,549,946...85,609,598
Ensembl chr 3:85,549,981...85,609,612
JBrowse link
G DLEC1 DLEC1 cilia and flagella associated protein treatment ISO DNA:hypermethylation:promoter: RGD PMID:27168825 RGD:11252164 NCBI chr23:7,813,305...7,889,322
Ensembl chr23:7,813,546...7,889,324
JBrowse link
G DNMT1 DNA methyltransferase 1 ISO mRNA:increased expression:CD34+ bone marrow cells RGD PMID:11222358 RGD:9588667 NCBI chr20:50,872,213...50,928,352
Ensembl chr20:50,879,527...50,928,029
JBrowse link
G DNMT3A DNA methyltransferase 3 alpha disease_progression
treatment
susceptibility
ISO DNA:missense mutation:exon:p.R882 (human)
DNA:mutation::
DNA:hypomethylation: :
associated with Myelodysplastic Syndromes; DNA:mutations:cds:
OMIM
RGD
PMID:21415852 PMID:24512939 PMID:25609058 PMID:26242829 RGD:11041120 RGD:11041121 RGD:11041122 RGD:11041123 NCBI chr17:19,489,524...19,563,074
Ensembl chr17:19,492,193...19,563,902
JBrowse link
G DNMT3B DNA methyltransferase 3 beta disease_progression
susceptibility
ISO DNA:SNP:promoter: C>T46359(human)
mRNA:increased expression:CD34+ bone marrow cells
DNA:SNPs,haplotype: :rs1569686,rs2424908, rs6087990, rs6119954(human)
RGD PMID:11222358 PMID:16194411 PMID:23251566 PMID:24069326 RGD:9588667 RGD:9589071 RGD:9589103 RGD:9589108 NCBI chr24:22,096,386...22,123,378
Ensembl chr24:22,096,349...22,122,900
JBrowse link
G EHD3 EH domain containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr17:24,828,289...24,854,990
Ensembl chr17:24,828,372...24,853,400
JBrowse link
G EHMT2 euchromatic histone lysine methyltransferase 2 disease_progression ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:24532712 RGD:9589168 NCBI chr12:1,341,202...1,354,602
Ensembl chr12:1,341,191...1,354,584
JBrowse link
G EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19458359 NCBI chr16:27,389,850...27,410,154
Ensembl chr16:27,390,181...27,410,110
JBrowse link
G ENAH ENAH actin regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:26237430 NCBI chr 7:39,105,024...39,250,126
Ensembl chr 7:39,105,039...39,247,595
JBrowse link
G ENO2 enolase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr27:38,120,404...38,128,543
Ensembl chr27:38,119,413...38,129,182
JBrowse link
G EPHX1 epoxide hydrolase 1 no_association ISO DNA:SNPs:exon:rs1051740, rs2234922 (human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphism
DNA:missense mutations:exon:p.Y113H, p.H139R (human)
RGD
CTD
PMID:11849215 PMID:20731606 PMID:22200898 PMID:29605894 RGD:11252114 RGD:11252115 RGD:11252119 NCBI chr 7:38,964,319...39,004,902
Ensembl chr 7:38,964,338...38,999,238
JBrowse link
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit no_association
treatment
ISO DNA:SNP: :p.Q504K (human)
DNA:polymorphism: :p.R399Q (human)
RGD PMID:16507781 PMID:18604718 PMID:20141440 PMID:21942242 PMID:23397959 RGD:11252170 RGD:11252171 RGD:11252173 RGD:11252179 RGD:11252193 NCBI chr 1:110,130,353...110,146,660
Ensembl chr 1:110,130,481...110,146,602
JBrowse link
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit no_association
disease_progression
ISO associated with Myeloproliferative Disorders;DNA:polymorphism: :p.K751Q (rs13181) (human)
DNA:SNPs, haplotypes: :p.D312N, p.K751Q (human)
RGD PMID:20141440 PMID:21394217 PMID:22496165 PMID:23397959 RGD:11252173 RGD:11252193 RGD:11252198 RGD:11252209 NCBI chr 1:110,173,781...110,191,612
Ensembl chr 1:110,173,715...110,190,125
JBrowse link
G ERG ETS transcription factor ERG ISO CTD Direct Evidence: marker/mechanism CTD PMID:19822134 NCBI chr31:33,456,902...33,562,704
Ensembl chr31:33,497,209...33,515,272
JBrowse link
G ETV6 ETS variant transcription factor 6 ISO OMIM NCBI chr27:34,351,206...34,587,060
Ensembl chr27:34,343,390...34,587,060
JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit susceptibility
disease_progression
ISO DNA:mutations:cds:multiple (human)
mRNA:increased expression:bone marrow, mononuclear cell (human)
RGD PMID:21125401 PMID:22677129 PMID:23099237 RGD:10450874 RGD:10450876 RGD:10450887 NCBI chr16:1,926,443...1,991,995
Ensembl chr16:1,925,956...1,991,838
JBrowse link
G F3 coagulation factor III, tissue factor ISO RGD PMID:2617479 RGD:11340207 NCBI chr 6:54,709,581...54,720,603
Ensembl chr 6:54,708,471...54,720,607
JBrowse link
G FADD Fas associated via death domain disease_progression ISO RGD PMID:15520222 RGD:11341799 NCBI chr18:48,087,447...48,094,497 JBrowse link
G FANCA FA complementation group A ISO DNA, mRNA:deletions, decreased expression: :multiple RGD PMID:14749703 RGD:11344889 NCBI chr 5:63,778,149...63,838,869
Ensembl chr 5:63,778,212...63,838,823
JBrowse link
G FANCC FA complementation group C susceptibility ISO DNA:polymorphism:cds:p.S26F (human) RGD PMID:12670332 RGD:11046259 NCBI chr 1:71,388,931...71,678,019
Ensembl chr 1:71,487,601...71,678,506
JBrowse link
G FAS Fas cell surface death receptor susceptibility ISO DNA:polymorphism, haplotype:promoter:-1377 G>A, -670 G>A (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:7579353 PMID:8870373 PMID:12907599 RGD:11049150 RGD:11049452 NCBI chr26:38,738,811...38,763,298
Ensembl chr26:38,737,611...38,763,321
JBrowse link
G FERMT2 FERM domain containing kindlin 2 disease_progression ISO RGD PMID:22391155 RGD:11352307 NCBI chr 8:29,083,538...29,135,915
Ensembl chr 8:29,084,531...29,133,391
JBrowse link
G FERMT3 FERM domain containing kindlin 3 disease_progression ISO RGD PMID:22391155 RGD:11352307 NCBI chr18:52,833,954...52,851,775
Ensembl chr18:52,834,001...52,851,667
JBrowse link
G FGFR1 fibroblast growth factor receptor 1 treatment ISO RGD PMID:22683780 PMID:23777766 PMID:27005999 RGD:11352310 RGD:11352665 RGD:11352670 NCBI chr16:27,029,902...27,080,514
Ensembl chr16:27,031,588...27,078,261
JBrowse link
G FHL2 four and a half LIM domains 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr10:37,997,912...38,065,633
Ensembl chr10:37,997,942...38,065,330
JBrowse link
G FLT3 fms related receptor tyrosine kinase 3 treatment
disease_progression
ISO DNA:mutations:cds:
DNA:duplication mutation:cds:
OMIM
RGD
PMID:16642044 PMID:23969938 RGD:11049467 RGD:11049482 NCBI chr25:11,551,372...11,670,891
Ensembl chr25:11,581,206...11,692,284
JBrowse link
G FOXO1 forkhead box O1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr25:603,433...706,961
Ensembl chr25:603,543...702,825
JBrowse link
G FXYD6 FXYD domain containing ion transport regulator 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 5:15,801,790...15,807,601
Ensembl chr 5:15,771,390...15,807,601
JBrowse link
G GAS2L1 growth arrest specific 2 like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr26:22,615,531...22,620,605
Ensembl chr26:22,615,319...22,621,311
JBrowse link
G GATA1 GATA binding protein 1 disease_progression ISO RGD PMID:7579412 RGD:10450754 NCBI chr  X:41,991,321...41,998,319
Ensembl chr  X:41,971,582...41,998,303
JBrowse link
G GATA2 GATA binding protein 2 disease_progression ISO OMIM
RGD
PMID:22786876 PMID:25241285 RGD:11049510 RGD:11049515 NCBI chr20:2,472,251...2,488,380
Ensembl chr20:2,473,912...2,480,991
JBrowse link
G GFI1 growth factor independent 1 transcriptional repressor susceptibility ISO CTD Direct Evidence: marker/mechanism
DNA:SNP:cds:c.107G>A(rs34631763)(human)
CTD
RGD
PMID:17330099 PMID:20075157 RGD:11040450 NCBI chr 6:56,473,032...56,484,422
Ensembl chr 6:56,256,305...56,484,422
JBrowse link
G GFI1B growth factor independent 1B transcriptional repressor ISO mRNA:increased expression:bone marrow cell: RGD PMID:17156408 RGD:11040507 NCBI chr 9:51,380,697...51,394,679
Ensembl chr 9:51,380,696...51,392,812
JBrowse link
G GPATCH1 G-patch domain containing 1 ISO ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:28492532 NCBI chr 1:119,009,605...119,052,676
Ensembl chr 1:119,009,609...119,053,140
JBrowse link
G GPI glucose-6-phosphate isomerase ISO protein:increased expression:plasma: RGD PMID:6589021 RGD:11051848 NCBI chr 1:117,922,380...117,948,325
Ensembl chr 1:117,922,635...117,948,316
JBrowse link
G GPX1 glutathione peroxidase 1 susceptibility
disease_progression
treatment
ISO DNA:polymorphism: :p.P198L (human)
DNA:SNP: :c.599C>T (rs1050450) (human)
RGD PMID:22930375 PMID:26823947 PMID:26950655 RGD:11061561 RGD:11061784 RGD:11352817 NCBI chr20:39,889,165...39,890,253
Ensembl chr20:39,889,174...39,890,260
JBrowse link
G GSKIP GSK3B interacting protein ISO ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar NCBI chr 8:65,110,659...65,131,205
Ensembl chr 8:65,111,414...65,129,622
JBrowse link
G GSR glutathione-disulfide reductase ISO RGD PMID:24191316 RGD:11059506 NCBI chr16:33,633,949...33,680,411
Ensembl chr16:33,633,968...33,679,752
JBrowse link
G GSTP1 glutathione S-transferase pi 1 susceptibility ISO DNA:polymorphism:cds:p.I105V(human)
chemotherapy-induced;
RGD PMID:11553769 PMID:11906705 PMID:21729529 RGD:10755328 RGD:10755420 RGD:10755422 NCBI chr18:49,905,161...49,908,182
Ensembl chr18:49,905,161...49,908,182
JBrowse link
G GTF2I general transcription factor IIi ISO CTD Direct Evidence: marker/mechanism CTD PMID:18206229 NCBI chr 6:5,726,652...5,840,740
Ensembl chr 6:5,727,665...5,811,965
JBrowse link
G H1-0 H1.0 linker histone ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr10:26,827,748...26,829,909
Ensembl chr10:26,829,089...26,829,673
JBrowse link
G H1-2 H1.2 linker histone, cluster member ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr35:24,009,304...24,011,602 JBrowse link
G HGF hepatocyte growth factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:22683780 NCBI chr18:21,329,688...21,410,257
Ensembl chr18:21,332,817...21,410,263
JBrowse link
G HMOX1 heme oxygenase 1 ISO mRNA:increased expression:brain, spleen RGD PMID:19268504 RGD:10755700 NCBI chr10:28,744,404...28,751,544
Ensembl chr10:28,743,795...28,751,773
JBrowse link
G HOXA9 homeobox A9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22541086 NCBI chr14:40,336,829...40,340,533
Ensembl chr14:40,337,999...40,339,923
JBrowse link
G HRAS HRas proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Leukemia, acute myelogenous
ClinVar Annotator: match by term: Acute myelogenous leukemia
ClinVar Annotator: match by term: Acute myelocytic leukemia
ClinVar Annotator: match by term: Acute myeloid leukemia
ClinVar PMID:11150980 PMID:12835555 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 PMID:16443854 PMID:16835863 PMID:16881968 PMID:16969868 PMID:17054105 PMID:17211612 PMID:17384584 PMID:17412879 PMID:17979197 PMID:18039947 PMID:18042262 PMID:18247425 PMID:18978862 PMID:19206176 PMID:19213030 PMID:19255327 PMID:19371735 PMID:19382114 PMID:19669404 PMID:19773371 PMID:20660566 PMID:20859122 PMID:20979192 PMID:21438134 PMID:21495179 PMID:21686750 PMID:21834037 PMID:21850009 PMID:22087699 PMID:22256804 PMID:22317973 PMID:22495892 PMID:22499344 PMID:22683711 PMID:22726224 PMID:22926243 PMID:23093928 PMID:23096712 PMID:23406027 PMID:23429430 PMID:23751039 PMID:23884457 PMID:24006476 PMID:24033266 PMID:24129065 PMID:24169525 PMID:24224811 PMID:24390138 PMID:24803665 PMID:25157968 PMID:25326635 PMID:25741868 PMID:25914166 PMID:26619011 PMID:27195699 PMID:27589201 PMID:28027064 PMID:28139825 PMID:28492532 PMID:29493581 PMID:31394527 PMID:31775759 PMID:168335863 NCBI chr18:25,642,844...25,644,717
Ensembl chr18:25,642,844...25,644,717
JBrowse link
G HSPB1 heat shock protein family B (small) member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 6:7,487,164...7,488,576
Ensembl chr 6:7,487,250...7,488,576
JBrowse link
G ID2 inhibitor of DNA binding 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr17:5,956,924...5,958,833 JBrowse link
G IDH1 isocitrate dehydrogenase (NADP(+)) 1 disease_progression ISO DNA:mutation:cds:p.R132(human)
ClinVar Annotator: match by term: Acute myeloid leukemia
ClinVar Annotator: match by term: Leukemia, acute myelogenous
ClinVar Annotator: match by term: Acute myelogenous leukemia
CTD Direct Evidence: marker/mechanism
DNA:SNP::105C>T (rs11554137)(human)
RGD
ClinVar
CTD
PMID:18772396 PMID:19657110 PMID:19798509 PMID:19818334 PMID:20368543 PMID:20946881 PMID:21352804 PMID:21446021 PMID:22160010 PMID:22397365 PMID:22417203 PMID:22898539 PMID:23558169 PMID:24606448 PMID:25043048 PMID:25157968 PMID:25324972 PMID:25741868 PMID:26619011 PMID:27992414 PMID:27993330 PMID:29950729 RGD:11522718 RGD:11522721 NCBI chr37:16,512,027...16,531,269
Ensembl chr37:16,512,770...16,531,219
JBrowse link
G IDH2 isocitrate dehydrogenase (NADP(+)) 2 disease_progression ISO DNA:mutation:cds:p.R172(human)
ClinVar Annotator: match by term: Acute myeloid leukemia
ClinVar Annotator: match by term: Acute myelogenous leukemia
DNA:mutation:cds:p.R140 (human)
CTD Direct Evidence: marker/mechanism
RGD
ClinVar
CTD
PMID:20171147 PMID:20368543 PMID:20847235 PMID:20946881 PMID:21250968 PMID:21596855 PMID:21889589 PMID:21997850 PMID:22160010 PMID:22397365 PMID:22417203 PMID:22616558 PMID:22898539 PMID:23558173 PMID:23815907 PMID:23949315 PMID:24049096 PMID:24606448 PMID:25157968 PMID:25324972 PMID:25326635 PMID:25398939 PMID:25741868 PMID:26619011 PMID:27992414 PMID:28492532 RGD:11522718 RGD:11522721 NCBI chr 3:53,070,462...53,077,566
Ensembl chr 3:53,070,695...53,087,496
JBrowse link
G IFI30 IFI30 lysosomal thiol reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr20:44,819,862...44,823,261
Ensembl chr20:44,819,893...44,823,342
JBrowse link
G IL10 interleukin 10 disease_progression ISO RGD PMID:23357299 RGD:11046264 NCBI chr 7:5,933,285...5,937,057
Ensembl chr 7:5,933,285...5,937,057
JBrowse link
G IL1A interleukin 1 alpha treatment ISO RGD PMID:2460157 RGD:11051965 NCBI chr17:36,969,581...36,979,445
Ensembl chr17:36,970,573...36,979,435
JBrowse link
G IL4R interleukin 4 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:11918534 NCBI chr 6:19,254,183...19,280,973
Ensembl chr 6:19,254,487...19,389,291
JBrowse link
G IL6 interleukin 6 treatment
disease_progression
ISO human protein in a rat model RGD PMID:8892684 PMID:23357299 RGD:11046264 RGD:11062010 NCBI chr14:36,474,268...36,478,519
Ensembl chr14:36,473,394...36,478,519
JBrowse link
G INPP4B inositol polyphosphate-4-phosphatase type II B ISO CTD Direct Evidence: marker/mechanism CTD PMID:29415082 NCBI chr19:826,711...1,192,340
Ensembl chr19:850,784...1,186,498
JBrowse link
G INSL6 insulin like 6 ISO ClinVar Annotator: match by term: Leukemia, acute myelogenous
ClinVar Annotator: match by term: Acute myelogenous leukemia
ClinVar PMID:15781101 PMID:15793561 PMID:15858187 PMID:16081687 PMID:16247455 PMID:16293597 PMID:16325696 PMID:16603627 PMID:16707754 PMID:16709929 PMID:16762626 PMID:17989398 PMID:18256599 PMID:18394554 PMID:19036091 PMID:19287384 PMID:19293426 PMID:20339092 PMID:20631743 PMID:20703299 PMID:21120162 PMID:21689158 PMID:22041374 PMID:22422826 PMID:22571758 PMID:22818858 PMID:22829971 PMID:23115274 PMID:24404189 PMID:24986690 PMID:25043017 PMID:25157968 PMID:25671252 PMID:25741868 PMID:32581362 NCBI chr 1:93,457,854...93,474,777
Ensembl chr 1:93,459,945...93,474,793
JBrowse link
G ITGAV integrin subunit alpha V treatment ISO RGD PMID:23770013 RGD:10755448 NCBI chr36:28,815,215...28,890,569
Ensembl chr36:28,804,013...28,887,430
JBrowse link
G ITGB3 integrin subunit beta 3 treatment ISO RGD PMID:23770013 RGD:10755448 NCBI chr 9:9,179,667...9,231,061
Ensembl chr 9:9,182,562...9,231,451
JBrowse link
G JAK1 Janus kinase 1 ISO ClinVar Annotator: match by term: Leukemia, acute myelogenous ClinVar PMID:16239216 PMID:19139102 PMID:19470474 PMID:19838194 PMID:21436584 PMID:21680795 NCBI chr 5:45,251,653...45,408,571
Ensembl chr 5:45,251,653...45,408,571
JBrowse link
G JAK2 Janus kinase 2 ISO OMIM NCBI chr 1:93,321,055...93,438,898
Ensembl chr 1:93,142,635...93,435,997
JBrowse link
G KAT6A lysine acetyltransferase 6A ISO human gene in a mouse model;DNA:translocation:exon RGD PMID:12676584 RGD:9590334 NCBI chr16:23,604,629...23,717,047
Ensembl chr16:23,604,200...23,724,252
JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase ISO OMIM NCBI chr13:47,108,442...47,190,935
Ensembl chr13:47,108,504...47,190,029
JBrowse link
G KLF1 Kruppel like factor 1 disease_progression ISO RGD PMID:19097174 RGD:10769344 NCBI chr20:49,295,097...49,298,668
Ensembl chr20:49,295,195...49,298,602
JBrowse link
G KMT2A lysine methyltransferase 2A ISO DNA:rearrangements
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:8361504 PMID:10339604 PMID:26237430 RGD:1625285 NCBI chr 5:15,212,559...15,302,825
Ensembl chr 5:15,217,348...15,270,971
JBrowse link
G KMT2B lysine methyltransferase 2B susceptibility ISO RGD PMID:25079327 RGD:9588599 NCBI chr 1:116,894,024...116,913,464
Ensembl chr 1:116,893,074...116,913,472
JBrowse link
G KMT2C lysine methyltransferase 2C ISO CTD Direct Evidence: marker/mechanism CTD PMID:24794707 NCBI chr16:15,962,045...16,117,601
Ensembl chr16:15,963,901...16,158,408
JBrowse link
G KRAS KRAS proto-oncogene, GTPase ISO OMIM NCBI chr27:22,261,753...22,296,704
Ensembl chr27:22,257,941...22,293,369
JBrowse link
G LOC100686511 myeloid cell surface antigen CD33 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12921496 NCBI chr 1:105,722,187...105,731,616 JBrowse link
G LOC478670 LIM domain containing preferred translocation partner in lipoma ISO OMIM NCBI chr34:20,538,580...21,157,978
Ensembl chr34:20,632,193...21,142,914
JBrowse link
G LOC607874 cystatin-C-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr23:49,562...53,618 JBrowse link
G LPAR1 lysophosphatidic acid receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr11:65,690,806...65,822,166
Ensembl chr11:65,692,973...65,822,312
JBrowse link
G LRP3 LDL receptor related protein 3 ISO ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:28492532 NCBI chr 1:118,924,195...118,934,687
Ensembl chr 1:118,926,861...118,929,769
JBrowse link
G LRRC56 leucine rich repeat containing 56 ISO ClinVar Annotator: match by term: Acute myeloid leukemia
ClinVar Annotator: match by term: Acute myelogenous leukemia
ClinVar Annotator: match by term: Acute myelocytic leukemia
ClinVar Annotator: match by term: Leukemia, acute myelogenous
ClinVar PMID:11150980 PMID:12835555 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 PMID:16443854 PMID:16835863 PMID:16881968 PMID:16969868 PMID:17054105 PMID:17211612 PMID:17384584 PMID:17412879 PMID:17979197 PMID:18039947 PMID:18042262 PMID:18247425 PMID:18978862 PMID:19206176 PMID:19213030 PMID:19255327 PMID:19371735 PMID:19382114 PMID:19669404 PMID:19773371 PMID:20660566 PMID:20859122 PMID:20979192 PMID:21438134 PMID:21495179 PMID:21686750 PMID:21834037 PMID:21850009 PMID:22087699 PMID:22256804 PMID:22317973 PMID:22495892 PMID:22499344 PMID:22683711 PMID:22726224 PMID:22926243 PMID:23093928 PMID:23096712 PMID:23406027 PMID:23429430 PMID:23751039 PMID:23884457 PMID:24006476 PMID:24033266 PMID:24129065 PMID:24169525 PMID:24224811 PMID:24390138 PMID:24803665 PMID:25157968 PMID:25326635 PMID:25741868 PMID:25914166 PMID:26619011 PMID:27195699 PMID:27589201 PMID:28027064 PMID:28139825 PMID:28492532 PMID:29493581 PMID:31394527 PMID:31775759 PMID:168335863 NCBI chr18:25,647,024...25,662,646
Ensembl chr18:25,647,882...25,664,220
JBrowse link
G LYL1 LYL1 basic helix-loop-helix family member ISO CTD Direct Evidence: marker/mechanism CTD PMID:16094422 NCBI chr20:49,109,358...49,113,911 JBrowse link
G MDM2 MDM2 proto-oncogene disease_progression ISO RGD PMID:11064355 RGD:11251749 NCBI chr10:10,936,288...10,963,118
Ensembl chr10:10,893,719...10,962,596
JBrowse link
G MECOM MDS1 and EVI1 complex locus ISO CTD Direct Evidence: marker/mechanism CTD PMID:30472098 NCBI chr34:33,747,495...34,299,389
Ensembl chr34:33,748,843...34,299,276
JBrowse link
G MEFV MEFV innate immuity regulator, pyrin susceptibility ISO DNA:polymorphisms:cds:p.M694V,E148Q(human) RGD PMID:22351163 RGD:11531114 NCBI chr 6:37,964,776...37,984,830
Ensembl chr 6:37,970,608...37,983,737
JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:22683780 NCBI chr14:55,599,047...55,711,626
Ensembl chr14:55,598,337...55,724,027
JBrowse link
G MIR155 microRNA mir-155 ISO miRNA:increased expression:blood
miRNA:decreased expression:peripheral blood mononuclear cell
RGD PMID:26923190 PMID:28989535 RGD:24922214 RGD:25671477 NCBI chr31:21,078,768...21,078,828
Ensembl chr31:21,078,758...21,078,833
JBrowse link
G MLF1 myeloid leukemia factor 1 ISO ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:25741868 NCBI chr23:51,918,504...51,935,164
Ensembl chr23:51,901,983...51,933,796
JBrowse link
G MLLT10 MLLT10 histone lysine methyltransferase DOT1L cofactor ISO OMIM NCBI chr 2:11,349,864...11,607,194
Ensembl chr 2:11,349,856...11,596,398
JBrowse link
G MN1 MN1 proto-oncogene, transcriptional regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:19822134 NCBI chr26:21,216,912...21,261,518
Ensembl chr26:21,216,837...21,261,031
JBrowse link
G MTHFR methylenetetrahydrofolate reductase ISO DNA:SNPs: :677C>T, 1298A>C(human) RGD PMID:17156840 RGD:10449408 NCBI chr 2:84,445,526...84,457,435
Ensembl chr 2:84,380,919...84,536,818
JBrowse link
G MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase susceptibility ISO DNA:polymorphism: :66A>G(human) RGD PMID:18774170 RGD:11075096 NCBI chr34:6,068,572...6,119,580
Ensembl chr34:6,070,046...6,098,312
JBrowse link
G MX1 MX dynamin like GTPase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr31:35,898,206...35,929,802
Ensembl chr31:35,860,590...35,951,350
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:25956709 NCBI chr13:25,200,772...25,205,309
Ensembl chr13:25,200,577...25,205,309
JBrowse link
G MYH11 myosin heavy chain 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18206229 PMID:27798625 NCBI chr 6:28,041,330...28,157,277
Ensembl chr 6:28,041,318...28,262,184
JBrowse link
G NCOA2 nuclear receptor coactivator 2 ISO human gene in a mouse model;DNA:translocation:exon RGD PMID:12676584 RGD:9590334 NCBI chr29:19,253,849...19,471,640
Ensembl chr29:19,222,842...19,545,371
JBrowse link
G NECTIN2 nectin cell adhesion molecule 2 ISO CTD Direct Evidence: therapeutic CTD PMID:29855615 NCBI chr 1:110,543,140...110,569,168
Ensembl chr 1:110,543,247...110,569,143
JBrowse link
G NF1 neurofibromin 1 disease_progression
severity
ISO CTD Direct Evidence: marker/mechanism
DNA:deletion: :
CTD
RGD
PMID:12518368 PMID:21441929 PMID:23460398 PMID:25822087 RGD:12754447 RGD:12789444 NCBI chr 9:41,467,460...41,679,388
Ensembl chr 9:41,469,416...41,679,382
JBrowse link
G NOS3 nitric oxide synthase 3 disease_progression ISO DNA:polymorphgism: : 894 G>T(human) RGD PMID:24684492 RGD:11533640 NCBI chr16:15,054,196...15,072,454
Ensembl chr16:15,011,344...15,072,277
JBrowse link
G NPM1 nucleophosmin 1 disease_progression
onset
ISO DNA:mutation:exon: OMIM
RGD
PMID:17957027 PMID:21441929 PMID:25992555 RGD:11049474 RGD:11070453 RGD:11534990 NCBI chr 4:40,756,464...40,770,174
Ensembl chr 4:40,756,465...40,770,175
JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 ISO DNA:SNP: :609C>T (human) RGD PMID:19456854 RGD:10769358 NCBI chr 5:79,979,593...79,990,875
Ensembl chr 5:79,978,865...79,989,860
JBrowse link
G NRAS NRAS proto-oncogene, GTPase disease_progression ISO DNA:missense mutation:cds:
ClinVar Annotator: match by term: Acute myelogenous leukemia
ClinVar Annotator: match by term: Acute myelocytic leukemia
ClinVar Annotator: match by term: Acute myeloid leukemia
ClinVar Annotator: match by term: Leukemia, acute myelogenous
CTD Direct Evidence: marker/mechanism
RGD
ClinVar
CTD
PMID:1654209 PMID:2278970 PMID:2407301 PMID:2674680 PMID:2989702 PMID:3102434 PMID:3122217 PMID:6587382 PMID:8120410 PMID:10598665 PMID:10821536 PMID:12460918 PMID:12727991 PMID:14508525 PMID:14982869 PMID:15046639 PMID:15831708 PMID:15899789 PMID:15951308 PMID:16273091 PMID:16291983 PMID:16434492 PMID:16518851 PMID:17332249 PMID:17384584 PMID:17517660 PMID:17699718 PMID:18375819 PMID:18390968 PMID:18633438 PMID:18668139 PMID:18794081 PMID:18948947 PMID:18952898 PMID:19047918 PMID:19075190 PMID:19657110 PMID:19775298 PMID:19880792 PMID:19966803 PMID:20130576 PMID:20149136 PMID:20179705 PMID:20406486 PMID:20619739 PMID:20736745 PMID:21079152 PMID:21107323 PMID:21263000 PMID:21283084 PMID:21305640 PMID:21576590 PMID:21729679 PMID:21829508 PMID:22144181 PMID:22407852 PMID:22499344 PMID:22718121 PMID:22761467 PMID:22773810 PMID:22962325 PMID:23076151 PMID:23134356 PMID:23392294 PMID:23400451 PMID:23414587 PMID:23431193 PMID:23515407 PMID:23538902 PMID:23569304 PMID:23614898 PMID:24006476 PMID:24033266 PMID:24148783 PMID:24284627 PMID:24370118 PMID:24671188 PMID:25157968 PMID:25204082 PMID:25348872 PMID:25695684 PMID:26619011 PMID:26821351 PMID:27050078 PMID:27992414 PMID:27993330 PMID:28098151 PMID:28492532 PMID:28594414 PMID:28780248 RGD:11060151 RGD:11070616 RGD:11535045 NCBI chr17:52,411,733...52,418,788
Ensembl chr17:52,411,733...52,418,788
JBrowse link
G NSD1 nuclear receptor binding SET domain protein 1 severity ISO DNA:translocations:multiple (human)
ClinVar Annotator: match by term: Acute myeloid leukemia
RGD
ClinVar
PMID:15942875 PMID:23630019 PMID:25741868 PMID:28492532 RGD:9590149 NCBI chr 4:36,058,351...36,214,254
Ensembl chr 4:36,063,134...36,210,999
JBrowse link
G NTRK3 neurotrophic receptor tyrosine kinase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29119387 NCBI chr 3:51,131,470...51,491,112
Ensembl chr 3:51,138,751...51,513,024
JBrowse link
G NUP214 nucleoporin 214 ISO OMIM NCBI chr 9:52,840,300...52,943,785
Ensembl chr 9:52,841,096...52,947,770
JBrowse link
G NUP98 nucleoporin 98 and 96 precursor ISO CTD Direct Evidence: marker/mechanism CTD PMID:21441929 NCBI chr21:26,231,585...26,348,019
Ensembl chr21:26,220,963...26,336,020
JBrowse link
G PAX5 paired box 5 ISO ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:25741868 NCBI chr11:53,194,905...53,390,204
Ensembl chr11:53,201,344...53,390,974
JBrowse link
G PDCD1 programmed cell death 1 treatment ISO RGD PMID:26712908 RGD:41410789 NCBI chr25:51,606,559...51,618,903
Ensembl chr25:51,608,173...51,618,723
JBrowse link
G PDE4B phosphodiesterase 4B ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 5:44,063,145...44,606,070
Ensembl chr 5:44,065,106...44,500,999
JBrowse link
G PICALM phosphatidylinositol binding clathrin assembly protein susceptibility ISO DNA:inversion: :inv(11)(q14q23) OMIM
RGD
PMID:12461747 RGD:1600760 NCBI chr21:13,437,819...13,540,167
Ensembl chr21:13,437,925...13,539,616
JBrowse link
G PIM2 Pim-2 proto-oncogene, serine/threonine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19458359 NCBI chr  X:42,072,495...42,077,741
Ensembl chr  X:42,073,457...42,077,543
JBrowse link
G PLCB1 phospholipase C beta 1 severity ISO mRNA:increased expression:blood (human) RGD PMID:20516454 RGD:11535940 NCBI chr24:13,337,285...13,996,218
Ensembl chr24:13,322,296...13,995,539
JBrowse link
G POU4F1 POU class 4 homeobox 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18206229 NCBI chr22:31,992,657...31,997,066 JBrowse link
G PRAME PRAME nuclear receptor transcriptional regulator ISO mRNA:increased expression:bone marrow, mononuclear cell (human) RGD PMID:20376794 RGD:11535023 NCBI chr26:27,124,901...27,137,772
Ensembl chr26:27,124,902...27,136,112
JBrowse link
G PSIP1 PC4 and SFRS1 interacting protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr11:35,746,064...35,788,473
Ensembl chr11:35,747,341...35,789,110
JBrowse link
G PTCH1 patched 1 ISO ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:25741868 PMID:28492532 PMID:28873162 NCBI chr 1:71,246,750...71,309,036
Ensembl chr 1:71,238,195...71,305,662
JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Acute myeloid leukemia
CTD
ClinVar
PMID:12717436 PMID:14644997 PMID:15385933 PMID:15710330 PMID:15928039 PMID:16358218 PMID:17972951 PMID:19047918 PMID:19179468 PMID:24033266 PMID:25097206 PMID:25395418 PMID:26619011 PMID:27069254 PMID:27992414 PMID:28098151 PMID:30868567 NCBI chr26:9,989,218...10,072,245
Ensembl chr26:9,989,425...10,067,481
JBrowse link
G PVR PVR cell adhesion molecule ISO CTD Direct Evidence: therapeutic CTD PMID:29855615 NCBI chr 1:110,692,906...110,713,209
Ensembl chr 1:110,697,911...110,754,296
JBrowse link
G PXDN peroxidasin ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr17:834,625...891,551
Ensembl chr17:836,434...875,117
JBrowse link
G RASGRP1 RAS guanyl releasing protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21441929 NCBI chr30:5,840,901...5,914,804
Ensembl chr30:5,841,738...5,914,810
JBrowse link
G RGS2 regulator of G protein signaling 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr38:6,200,237...6,203,491
Ensembl chr38:6,200,657...6,203,494
JBrowse link
G RHPN2 rhophilin Rho GTPase binding protein 2 ISO ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:28492532 NCBI chr 1:119,061,637...119,119,470
Ensembl chr 1:119,061,562...119,119,468
JBrowse link
G RTEL1 regulator of telomere elongation helicase 1 ISO ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:25741868 NCBI chr24:47,219,977...47,248,791 JBrowse link
G RUNX1 RUNX family transcription factor 1 ISO OMIM NCBI chr31:30,170,859...30,420,344
Ensembl chr31:30,170,605...30,420,839
JBrowse link
G RUNX1T1 RUNX1 partner transcriptional co-repressor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18206229 PMID:27798625 NCBI chr29:37,156,861...37,289,934
Ensembl chr29:37,158,659...37,297,879
JBrowse link
G RUNX3 RUNX family transcription factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18206229
G S100A10 S100 calcium binding protein A10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr17:60,984,138...60,994,915 JBrowse link
G S100A8 S100 calcium binding protein A8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21971985 NCBI chr 7:43,540,667...43,541,604
Ensembl chr 7:43,501,989...43,541,604
JBrowse link
G SEPTIN9 septin 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10339604 NCBI chr 9:3,495,764...3,571,755
Ensembl chr 9:3,448,793...3,616,732
JBrowse link
G SF3B1 splicing factor 3b subunit 1 ISO ClinVar Annotator: match by term: Leukemia, acute myelogenous
ClinVar Annotator: match by term: Acute myeloid leukemia
ClinVar PMID:21909114 PMID:21995386 PMID:23395771 PMID:23634996 PMID:26619011 NCBI chr37:6,922,150...6,962,474
Ensembl chr37:6,924,047...6,962,896
JBrowse link
G SF3B2 splicing factor 3b subunit 2 ISO ClinVar Annotator: match by term: Leukemia, acute myelogenous ClinVar PMID:26619011 NCBI chr18:51,197,924...51,212,397
Ensembl chr18:51,197,939...51,212,354
JBrowse link
G SGK1 serum/glucocorticoid regulated kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 1:27,086,431...27,196,601
Ensembl chr 1:27,087,361...27,196,521
JBrowse link
G SH3GL1 SH3 domain containing GRB2 like 1, endophilin A2 ISO OMIM NCBI chr20:55,279,622...55,311,579
Ensembl chr20:55,279,621...55,311,536
JBrowse link
G SLC7A10 solute carrier family 7 member 10 ISO ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:28492532 NCBI chr 1:118,908,087...118,923,034
Ensembl chr 1:118,907,184...118,923,215
JBrowse link
G SOD2 superoxide dismutase 2 disease_progression ISO protein:increased expression:serum RGD PMID:1596865 PMID:16769586 RGD:11035286 RGD:11035289 NCBI chr 1:48,943,472...48,955,158
Ensembl chr 1:48,836,262...48,955,706
JBrowse link
G SPARC secreted protein acidic and cysteine rich ISO CTD Direct Evidence: marker/mechanism CTD PMID:18206229 NCBI chr 4:57,659,541...57,682,147
Ensembl chr 4:57,659,650...57,681,711
JBrowse link
G SPI1 Spi-1 proto-oncogene ISO CTD Direct Evidence: marker/mechanism CTD PMID:26237430 NCBI chr18:42,253,849...42,269,497
Ensembl chr18:42,253,811...42,269,727
JBrowse link
G SPRY4 sprouty RTK signaling antagonist 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25822087 NCBI chr 2:37,199,890...37,213,710
Ensembl chr 2:37,203,609...37,208,858
JBrowse link
G SRSF2 serine and arginine rich splicing factor 2 severity ISO DNA:mutations:multiple (human) RGD PMID:22431577 RGD:11039017 NCBI chr 9:4,028,414...4,032,371
Ensembl chr 9:4,028,482...4,030,793
JBrowse link
G SRSF4 serine and arginine rich splicing factor 4 ISO mRNA:decreased expression: (human) RGD PMID:22722453 RGD:11039059 NCBI chr 2:71,418,626...71,434,140
Ensembl chr 2:71,394,037...71,471,997
JBrowse link
G STAT3 signal transducer and activator of transcription 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19796711 NCBI chr 9:20,539,660...20,614,631
Ensembl chr 9:20,539,697...20,612,672
JBrowse link
G SVIL supervillin ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr 2:16,004,160...16,234,434
Ensembl chr 2:16,004,951...16,174,218
JBrowse link
G SYNGR1 synaptogyrin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr10:25,685,079...25,735,940
Ensembl chr10:25,687,633...25,713,300
JBrowse link
G TCEA2 transcription elongation factor A2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr24:47,508,161...47,512,399
Ensembl chr24:47,508,136...47,537,250
JBrowse link
G TCL1A TCL1 family AKT coactivator A ISO ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar
G TCN2 transcobalamin 2 ISO protein:increased expression:: RGD PMID:1059479 RGD:11060122 NCBI chr26:23,693,664...23,710,342
Ensembl chr26:23,693,773...23,709,832
JBrowse link
G TEK TEK receptor tyrosine kinase ISO ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:19340004 NCBI chr11:45,278,375...45,377,300
Ensembl chr11:45,278,891...45,409,093
JBrowse link
G TERT telomerase reverse transcriptase disease_progression ISO OMIM
RGD
PMID:23826993 RGD:11038655 NCBI chr34:11,288,622...11,307,790
Ensembl chr34:11,288,622...11,307,951
JBrowse link
G TET2 tet methylcytosine dioxygenase 2 disease_progression ISO DNA:deletions RGD PMID:23389918 PMID:25200248 RGD:11038681 RGD:11038682 NCBI chr32:26,021,745...26,145,109
Ensembl chr32:26,059,693...26,143,536
JBrowse link
G TFPI2 tissue factor pathway inhibitor 2 ISO DNA:hypermethylation:promoter: RGD PMID:22052167 RGD:11060127 NCBI chr14:19,399,259...19,403,890
Ensembl chr14:19,399,720...19,403,708
JBrowse link
G TFR2 transferrin receptor 2 disease_progression ISO RGD PMID:15015967 RGD:11062090 NCBI chr 6:9,059,501...9,076,646
Ensembl chr 6:9,060,629...9,076,158
JBrowse link
G TGM6 transglutaminase 6 ISO ClinVar Annotator: match by term: Leukemia, acute myelogenous ClinVar PMID:21106500 NCBI chr24:18,698,016...18,721,975
Ensembl chr24:18,700,099...18,721,930
JBrowse link
G TMEM127 transmembrane protein 127 ISO ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:20923864 PMID:25741868 PMID:28492532 NCBI chr17:34,512,753...34,527,208
Ensembl chr17:34,512,792...34,523,692
JBrowse link
G TNFSF10 TNF superfamily member 10 ISO CTD Direct Evidence: therapeutic CTD PMID:12780785 NCBI chr34:36,719,249...36,734,989
Ensembl chr34:36,670,849...36,735,060
JBrowse link
G TNFSF8 TNF superfamily member 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:9058727 PMID:10512160 PMID:11918534 NCBI chr11:68,979,498...69,006,898
Ensembl chr11:68,982,360...69,007,355
JBrowse link
G TNFSF9 TNF superfamily member 9 ISO protein:increased expression:serum (human) RGD PMID:11564827 RGD:2317350 NCBI chr20:53,680,882...53,682,521
Ensembl chr20:53,679,880...53,682,706
JBrowse link
G TP53 tumor protein p53 treatment
disease_progression
ISO DNA:mutations: :
ClinVar Annotator: match by term: Acute myelogenous leukemia
ClinVar Annotator: match by term: Acute myeloid leukemia
ClinVar Annotator: match by term: Acute myelocytic leukemia
ClinVar Annotator: match by term: Leukemia, acute myelogenous
DNA:mutation: :
CTD Direct Evidence: marker/mechanism
RGD
ClinVar
CTD
PMID:1359493 PMID:1565143 PMID:1565144 PMID:1569604 PMID:1631137 PMID:1631151 PMID:1683921 PMID:1978757 PMID:2046748 PMID:2113594 PMID:2826609 PMID:7732013 PMID:7887414 PMID:7969167 PMID:8023157 PMID:8062826 PMID:8099841 PMID:8118819 PMID:8164043 PMID:8242631 PMID:8423216 PMID:8425176 PMID:8479749 PMID:8527048 PMID:8633021 PMID:9047394 PMID:9049183 PMID:9242456 PMID:9290701 PMID:9407971 PMID:9546439 PMID:9569050 PMID:9572492 PMID:9598730 PMID:9627118 PMID:9662334 PMID:9825943 PMID:10411893 PMID:10432928 PMID:10589545 PMID:10616528 PMID:10797439 PMID:10864200 PMID:10914716 PMID:10922393 PMID:11051239 PMID:11139324 PMID:11180592 PMID:11315715 PMID:11370630 PMID:11429705 PMID:11479205 PMID:11494139 PMID:11782540 PMID:11793474 PMID:11896595 PMID:11920959 PMID:12124823 PMID:12509279 PMID:12672316 PMID:12700230 PMID:12726864 PMID:12792784 PMID:12826609 PMID:12917626 PMID:14559903 PMID:15004724 PMID:15017592 PMID:15037740 PMID:15381368 PMID:15390294 PMID:15580553 PMID:15607980 PMID:15722483 PMID:15781620 PMID:15825182 PMID:15951970 PMID:15977174 PMID:16209708 PMID:16288208 PMID:16337994 PMID:16401470 PMID:16489069 PMID:16494995 PMID:16508005 PMID:16633321 PMID:16682957 PMID:16778209 PMID:16818505 PMID:16861262 PMID:17015838 PMID:17311302 PMID:17390010 PMID:17401428 PMID:17417627 PMID:17427234 PMID:17530187 PMID:17540308 PMID:17567834 PMID:17606709 PMID:17636407 PMID:17724467 PMID:17875924 PMID:18307025 PMID:18511570 PMID:18555592 PMID:18685109 PMID:19101993 PMID:19336573 PMID:19367569 PMID:19378321 PMID:19405127 PMID:19462533 PMID:19556618 PMID:19681600 PMID:19834951 PMID:19930417 PMID:20013323 PMID:20028212 PMID:20113312 PMID:20127978 PMID:20128691 PMID:20308654 PMID:20407015 PMID:20506564 PMID:20516128 PMID:20522432 PMID:20693561 PMID:20805372 PMID:21056685 PMID:21187651 PMID:21232794 PMID:21305319 PMID:21343334 PMID:21356188 PMID:21483000 PMID:21484931 PMID:21514416 PMID:21519010 PMID:21535297 PMID:21552135 PMID:21601526 PMID:21761402 PMID:22090360 PMID:22110706 PMID:22114072 PMID:22186996 PMID:22265402 PMID:22427690 PMID:22540896 PMID:22713868 PMID:22811390 PMID:22862161 PMID:22899716 PMID:22915647 PMID:22919068 PMID:22923379 PMID:22999923 PMID:23161690 PMID:23172776 PMID:23246812 PMID:23265383 PMID:23315175 PMID:23334668 PMID:23538418 PMID:23630318 PMID:23667202 PMID:23713777 PMID:23950206 PMID:23967324 PMID:24033266 PMID:24038938 PMID:24256616 PMID:24381225 PMID:24395441 PMID:24487413 PMID:24501221 PMID:24573247 PMID:24603336 PMID:24641375 PMID:24651012 PMID:24651015 PMID:24677579 PMID:24702488 PMID:24744791 PMID:24810334 PMID:24836762 PMID:25157968 PMID:25339994 PMID:25412846 PMID:25433984 PMID:25503501 PMID:25525159 PMID:25573287 PMID:25584008 PMID:25587027 PMID:25741868 PMID:25787918 PMID:25822087 PMID:25896519 PMID:25925845 PMID:25927356 PMID:25945745 PMID:25952993 PMID:26014290 PMID:26230955 PMID:26425688 PMID:26467025 PMID:26497680 PMID:26534844 PMID:26554828 PMID:26585234 PMID:26619011 PMID:26659639 PMID:26681312 PMID:26787237 PMID:26822237 PMID:26845104 PMID:27022024 PMID:27276561 PMID:27374712 PMID:27463065 PMID:27501770 PMID:27533082 PMID:27622479 PMID:27680515 PMID:27683180 PMID:27714481 PMID:27724982 PMID:27873457 PMID:27895058 PMID:27959731 PMID:28135145 PMID:28152038 PMID:28369373 PMID:28453743 PMID:28472496 PMID:28476805 PMID:28477316 PMID:28492532 PMID:28724667 PMID:28861920 PMID:28975465 PMID:29025599 PMID:29070607 PMID:29324801 PMID:29478780 PMID:29489754 PMID:29752822 PMID:29753700 PMID:29979965 PMID:30076369 PMID:30128536 PMID:30216591 PMID:30224644 PMID:30311369 PMID:30327374 PMID:30352134 PMID:30720243 PMID:30816478 PMID:30840781 PMID:31016814 PMID:31206626 PMID:31300551 PMID:31775759 PMID:32000721 PMID:32295079 RGD:11057925 RGD:11073714 RGD:11075071 NCBI chr 5:32,561,406...32,565,149
Ensembl chr 5:32,560,598...32,574,109
JBrowse link
G TRH thyrotropin releasing hormone ISO CTD Direct Evidence: marker/mechanism CTD PMID:18206229 NCBI chr20:5,219,495...5,222,914
Ensembl chr20:5,219,594...5,222,866
JBrowse link
G TRIO trio Rho guanine nucleotide exchange factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:18206229 NCBI chr34:271,572...505,656
Ensembl chr34:272,290...505,636
JBrowse link
G TSC1 TSC complex subunit 1 ISO ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:25741868 PMID:28492532 NCBI chr 9:51,409,307...51,459,546
Ensembl chr 9:51,425,937...51,454,677
JBrowse link
G TSC2 TSC complex subunit 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19250671 NCBI chr 6:38,865,509...38,898,977
Ensembl chr 6:38,865,507...38,898,960
JBrowse link
G TUBB2A tubulin beta 2A class IIa ISO CTD Direct Evidence: marker/mechanism CTD PMID:17330099 NCBI chr35:3,448,402...3,450,783
Ensembl chr35:3,448,435...3,452,091
JBrowse link
G TYMS thymidylate synthetase susceptibility ISO DNA:repeats,insertion/deletion:5'UTR, 3'UTR: RGD PMID:18774170 RGD:11075096 NCBI chr 7:67,487,927...67,497,747
Ensembl chr 7:67,487,927...67,497,747
JBrowse link
G U2AF1 U2 small nuclear RNA auxiliary factor 1 ISO ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:22158538 PMID:23029227 PMID:23861105 PMID:24498085 PMID:26619011 NCBI chr31:37,263,265...37,276,710 JBrowse link
G VEGFA vascular endothelial growth factor A disease_progression ISO DNA:SNP,haplotype: :(rs3025039),(rs699947),(rs833061)(human) RGD PMID:17983459 RGD:13432134 NCBI chr12:12,209,032...12,224,978
Ensembl chr12:12,208,231...12,224,965
JBrowse link
G VOPP1 VOPP1 WW domain binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:18206229 NCBI chr18:6,282,050...6,387,687
Ensembl chr18:6,282,426...6,386,703
JBrowse link
G VSIG4 V-set and immunoglobulin domain containing 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18206229 NCBI chr  X:50,839,979...50,881,684
Ensembl chr  X:50,803,330...50,881,618
JBrowse link
G WDR88 WD repeat domain 88 ISO ClinVar Annotator: match by term: Acute myeloid leukemia ClinVar PMID:28492532 NCBI chr 1:118,962,602...119,007,836
Ensembl chr 1:118,962,605...119,007,759
JBrowse link
G WT1 WT1 transcription factor ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Acute myeloid leukemia
CTD
ClinVar
PMID:19822134 PMID:24374862 PMID:24422723 PMID:24521058 PMID:24659740 PMID:24667279 PMID:24671364 PMID:25741868 PMID:27992414 NCBI chr18:35,099,660...35,148,767
Ensembl chr18:35,103,934...35,148,000
JBrowse link
G ZBTB7A zinc finger and BTB domain containing 7A ISO CTD Direct Evidence: marker/mechanism CTD PMID:27798625 NCBI chr20:55,517,531...55,527,071
Ensembl chr20:55,505,916...55,523,736
JBrowse link
G ZFP91 ZFP91 zinc finger protein, atypical E3 ubiquitin ligase ISO RGD PMID:12738986 RGD:727221 NCBI chr18:37,762,200...37,809,070 JBrowse link
Acute Myelomonocytic Leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARHGAP26 Rho GTPase activating protein 26 ISO juvenile myelomonocytic leukemia, OMIM:607785 translocation t(5;11)(q31;q23) fusing ARHGAP26 to MLL in one allele and point mutation A1255G/Asn417Ser or one of two insertions in second allele RGD PMID:10908648 RGD:1599311 NCBI chr 2:37,627,448...38,045,589
Ensembl chr 2:37,626,698...38,040,079
JBrowse link
G CBFB core-binding factor subunit beta susceptibility ISO DNA:inversion: :inv(16)(p13q22)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:8351518 PMID:10958941 RGD:1599543 NCBI chr 5:82,253,496...82,313,765
Ensembl chr 5:82,255,617...82,313,168
JBrowse link
G CDKN2B cyclin dependent kinase inhibitor 2B ISO RGD PMID:14681685 RGD:11252167 NCBI chr11:41,259,627...41,264,832 JBrowse link
G FLT3 fms related receptor tyrosine kinase 3 treatment ISO RGD PMID:22187040 RGD:11049503 NCBI chr25:11,551,372...11,670,891
Ensembl chr25:11,581,206...11,692,284
JBrowse link
G GMPS guanine monophosphate synthase ISO treatment-related acute type M4 myeloid leukemia; chromosomal translocation resulted in a fusion of MLL and GMPS genes RGD PMID:11110714 RGD:1598998 NCBI chr23:49,569,571...49,645,999
Ensembl chr23:49,569,531...49,699,199
JBrowse link
G KMT2A lysine methyltransferase 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:8282816 NCBI chr 5:15,212,559...15,302,825
Ensembl chr 5:15,217,348...15,270,971
JBrowse link
G MYH11 myosin heavy chain 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10958941 NCBI chr 6:28,041,330...28,157,277
Ensembl chr 6:28,041,318...28,262,184
JBrowse link
acute promyelocytic leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12556562 NCBI chr 8:72,317,399...72,335,686
Ensembl chr 8:72,317,869...72,335,193
JBrowse link
G AQP9 aquaporin 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23563754 NCBI chr30:23,223,413...23,271,893
Ensembl chr30:23,225,331...23,269,076
JBrowse link
G ASXL1 ASXL transcriptional regulator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26285909 NCBI chr24:21,725,126...21,804,745
Ensembl chr24:21,661,059...21,802,815
JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27770503 NCBI chr 9:2,930,308...2,959,307 JBrowse link
G CCL7 C-C motif chemokine ligand 7 ISO RGD PMID:19828696 RGD:5130982 NCBI chr 9:38,994,638...38,996,103
Ensembl chr 9:38,993,911...39,010,483
JBrowse link
G CD44 CD44 molecule ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:16208414 PMID:17349212 NCBI chr18:32,735,493...32,826,483
Ensembl chr18:32,737,907...32,827,107
JBrowse link
G CDKN2B cyclin dependent kinase inhibitor 2B disease_progression ISO DNA:hyprmethylation:promoter: RGD PMID:12750706 RGD:11252187 NCBI chr11:41,259,627...41,264,832 JBrowse link
G CEBPA CCAAT enhancer binding protein alpha ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:16788101 PMID:26285909 NCBI chr 1:118,846,252...118,851,045 JBrowse link
G CEBPE CCAAT enhancer binding protein epsilon ISO CTD Direct Evidence: therapeutic CTD PMID:16788101 NCBI chr 8:3,423,046...3,425,595
Ensembl chr 8:3,423,040...3,425,217
JBrowse link
G DAPK2 death associated protein kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28978663 NCBI chr30:28,440,616...28,565,089
Ensembl chr30:28,441,161...28,565,566
JBrowse link
G DNMT3A DNA methyltransferase 3 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:26285909 NCBI chr17:19,489,524...19,563,074
Ensembl chr17:19,492,193...19,563,902
JBrowse link
G F3 coagulation factor III, tissue factor ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:10726043 PMID:16206674 RGD:11340216 NCBI chr 6:54,709,581...54,720,603
Ensembl chr 6:54,708,471...54,720,607
JBrowse link
G FLT3 fms related receptor tyrosine kinase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17454189 PMID:24160850 PMID:26285909 NCBI chr25:11,551,372...11,670,891
Ensembl chr25:11,581,206...11,692,284
JBrowse link
G FNDC3B fibronectin type III domain containing 3B ISO CTD Direct Evidence: marker/mechanism CTD PMID:28314734 NCBI chr34:36,373,966...36,640,851
Ensembl chr34:36,302,386...36,637,583
JBrowse link
G GLI1 GLI family zinc finger 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23867347 NCBI chr10:1,565,306...1,575,971
Ensembl chr10:1,565,244...1,575,982
JBrowse link
G GLI2 GLI family zinc finger 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23867347 NCBI chr19:29,128,401...29,383,324
Ensembl chr19:29,130,227...29,383,658
JBrowse link
G IDH1 isocitrate dehydrogenase (NADP(+)) 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26285909 NCBI chr37:16,512,027...16,531,269
Ensembl chr37:16,512,770...16,531,219
JBrowse link
G IDH2 isocitrate dehydrogenase (NADP(+)) 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26285909 NCBI chr 3:53,070,462...53,077,566
Ensembl chr 3:53,070,695...53,087,496
JBrowse link
G IFNG interferon gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:22617429 NCBI chr10:10,406,866...10,411,698
Ensembl chr10:10,406,867...10,411,698
JBrowse link
G IL17A interleukin 17A ISO CTD Direct Evidence: marker/mechanism CTD PMID:22617429 NCBI chr12:19,854,129...19,862,521
Ensembl chr12:19,854,129...19,862,513
JBrowse link
G IRF2BP2 interferon regulatory factor 2 binding protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25583766 NCBI chr 4:5,242,225...5,249,371
Ensembl chr 4:5,244,869...5,247,247
JBrowse link
G ITGAL integrin subunit alpha L ISO CTD Direct Evidence: marker/mechanism CTD PMID:16764927 NCBI chr 6:17,605,611...17,645,134
Ensembl chr 6:17,605,760...17,644,986
JBrowse link
G ITGAM integrin subunit alpha M ISO CTD Direct Evidence: marker/mechanism CTD PMID:16764927 NCBI chr 6:16,944,062...16,996,525
Ensembl chr 6:16,808,971...16,996,286
JBrowse link
G ITGAX integrin subunit alpha X ISO CTD Direct Evidence: marker/mechanism CTD PMID:16764927 NCBI chr 6:16,898,143...16,927,270
Ensembl chr 6:16,808,971...16,996,286
JBrowse link
G ITGB2 integrin subunit beta 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16764927 NCBI chr31:38,520,733...38,547,003
Ensembl chr31:38,521,103...38,547,018
JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:26285909 NCBI chr13:47,108,442...47,190,935
Ensembl chr13:47,108,504...47,190,029
JBrowse link
G KMT2E lysine methyltransferase 2E (inactive) severity ISO mRNA:decreased expression:peripheral blood, bone marrow, mononuclear cells (human) RGD PMID:24796963 RGD:9588539 NCBI chr18:15,240,631...15,332,850
Ensembl chr18:15,239,994...15,332,828
JBrowse link
G LOC487387 RAP1 GTPase activating protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:22614916 NCBI chr 2:77,509,592...77,554,620
Ensembl chr 2:77,527,914...77,544,205
JBrowse link
G MIR15A microRNA mir-15a ISO CTD Direct Evidence: therapeutic CTD PMID:21056550 NCBI chr22:1,846,880...1,846,938
Ensembl chr22:1,846,866...1,846,960
JBrowse link
G MIR16-1 microRNA mir-16-1 ISO CTD Direct Evidence: therapeutic CTD PMID:21056550 NCBI chr22:1,847,020...1,847,084
Ensembl chr22:1,847,007...1,847,093
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor onset ISO mRNA:increased expression:promyelocyte: RGD PMID:21059853 RGD:11532756 NCBI chr13:25,200,772...25,205,309
Ensembl chr13:25,200,577...25,205,309
JBrowse link
G NCAM1 neural cell adhesion molecule 1 disease_progression ISO RGD PMID:24296270 RGD:40907062 NCBI chr 5:19,895,587...20,192,334
Ensembl chr 5:19,895,613...20,191,995
JBrowse link
G NPM1 nucleophosmin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14508522 PMID:26285909 NCBI chr 4:40,756,464...40,770,174
Ensembl chr 4:40,756,465...40,770,175
JBrowse link
G NRAS NRAS proto-oncogene, GTPase ISO CTD Direct Evidence: marker/mechanism CTD PMID:26285909 NCBI chr17:52,411,733...52,418,788
Ensembl chr17:52,411,733...52,418,788
JBrowse link
G NUMA1 nuclear mitotic apparatus protein 1 ISO OMIM NCBI chr21:26,000,579...26,076,281
Ensembl chr21:26,037,095...26,075,549
JBrowse link
G PLAT plasminogen activator, tissue type ISO protein:increased expression:leukocyte (human) RGD PMID:10861807 RGD:11541060 NCBI chr16:23,469,590...23,496,013 JBrowse link
G PML PML nuclear body scaffold ISO CTD Direct Evidence: marker/mechanism
human PML/RARA gene fusion in a mouse model
CTD
RGD
PMID:8616088 PMID:9122233 PMID:10742073 PMID:14706140 PMID:16788101 PMID:16835227 PMID:16891316 PMID:16935935 PMID:17294898 PMID:17649720 PMID:19029980 PMID:19035177 PMID:19884644 PMID:19887701 PMID:21345080 PMID:21613260 PMID:22213200 PMID:23208507 PMID:23734343 PMID:26285909 PMID:26728337 RGD:41404695 NCBI chr30:37,232,337...37,278,434
Ensembl chr30:37,232,306...37,277,741
JBrowse link
G PRAME PRAME nuclear receptor transcriptional regulator severity ISO mRNA:increased expression:bone marrow (human) RGD PMID:18815192 RGD:11535037 NCBI chr26:27,124,901...27,137,772
Ensembl chr26:27,124,902...27,136,112
JBrowse link
G PRKAR1A protein kinase cAMP-dependent type I regulatory subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:17712046 NCBI chr 9:15,180,940...15,203,035
Ensembl chr 9:15,181,393...15,200,683
JBrowse link
G RARA retinoic acid receptor alpha ISO OMIM NCBI chr 9:22,254,803...22,298,614
Ensembl chr 9:22,254,806...22,289,459
JBrowse link
G SMO smoothened, frizzled class receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:23867347 NCBI chr14:7,518,871...7,527,703
Ensembl chr14:7,518,856...7,528,033
JBrowse link
G TET2 tet methylcytosine dioxygenase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26285909 NCBI chr32:26,021,745...26,145,109
Ensembl chr32:26,059,693...26,143,536
JBrowse link
G THBD thrombomodulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16206674 NCBI chr24:599,773...601,649
Ensembl chr24:599,773...601,649
JBrowse link
G TMEM127 transmembrane protein 127 ISO ClinVar Annotator: match by term: Acute promyelocytic leukemia ClinVar PMID:25741868 PMID:28492532 NCBI chr17:34,512,753...34,527,208
Ensembl chr17:34,512,792...34,523,692
JBrowse link
G TOP2A DNA topoisomerase II alpha ISO ClinVar Annotator: match by term: Dna topoisomerase II, resistance to inhibition of, by amsacrine ClinVar PMID:1651812 NCBI chr 9:22,207,501...22,237,497
Ensembl chr 9:22,207,638...22,237,496
JBrowse link
G WT1 WT1 transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:26285909 NCBI chr18:35,099,660...35,148,767
Ensembl chr18:35,103,934...35,148,000
JBrowse link
G ZBTB16 zinc finger and BTB domain containing 16 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:8387545 PMID:23208507 RGD:1599922 NCBI chr 5:19,082,594...19,284,360
Ensembl chr 5:19,087,154...19,267,628
JBrowse link
adult T-cell leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BIRC5 baculoviral IAP repeat containing 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16497974 NCBI chr 9:2,930,308...2,959,307 JBrowse link
G BMP6 bone morphogenetic protein 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18688853 NCBI chr35:7,780,763...7,833,095
Ensembl chr35:7,804,231...7,831,845
JBrowse link
G CARD11 caspase recruitment domain family member 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr 6:14,273,115...14,331,029
Ensembl chr 6:14,210,114...14,332,094
JBrowse link
G CCR4 C-C motif chemokine receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr23:3,844,072...3,847,770
Ensembl chr23:3,844,173...3,845,255
JBrowse link
G CCR7 C-C motif chemokine receptor 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr 9:22,077,976...22,092,818
Ensembl chr 9:22,068,775...22,090,656
JBrowse link
G CD163 CD163 molecule disease_progression ISO protein:increased expression:lymph node tumor (human) RGD PMID:23557330 RGD:42721976 NCBI chr27:37,669,757...37,700,746
Ensembl chr27:37,669,827...37,753,106
JBrowse link
G CD274 CD274 molecule disease_progression ISO RGD PMID:27418641 RGD:41412177 NCBI chr 1:93,461,735...93,605,772
Ensembl chr 1:93,585,518...93,603,522
JBrowse link
G CD28 CD28 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr37:12,503,849...12,536,362
Ensembl chr37:12,503,811...12,532,854
JBrowse link
G CD68 CD68 molecule disease_progression ISO protein:increased expression:lymph node tumor (human) RGD PMID:23557330 RGD:42721976 NCBI chr 5:32,500,899...32,503,355
Ensembl chr 5:32,501,380...32,503,183
JBrowse link
G CD80 CD80 molecule ISO RGD PMID:10590132 RGD:6902938 NCBI chr33:23,177,136...23,208,421
Ensembl chr33:23,177,138...23,201,380
JBrowse link
G CD86 CD86 molecule ISO RGD PMID:10590132 RGD:6902938 NCBI chr33:25,256,267...25,318,855
Ensembl chr33:25,256,267...25,318,087
JBrowse link
G CSNK1A1 casein kinase 1 alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr 4:59,435,530...59,485,591
Ensembl chr 4:59,435,764...59,483,475
JBrowse link
G CSNK2A1 casein kinase 2 alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr24:20,333,593...20,390,341 JBrowse link
G CSNK2B casein kinase 2 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr12:1,149,467...1,154,417
Ensembl chr12:1,149,548...1,154,418
JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr37:12,647,712...12,653,874
Ensembl chr37:12,634,563...12,653,874
JBrowse link
G FAS Fas cell surface death receptor susceptibility ISO protein:increased expression:peripheral blood mononuclear cell:
DNA:polymorphism:promoter: -670 G>A(human)
RGD PMID:7513372 PMID:17962369 RGD:11049147 RGD:11049453 NCBI chr26:38,738,811...38,763,298
Ensembl chr26:38,737,611...38,763,321
JBrowse link
G FOXP3 forkhead box P3 disease_progression ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:23797717 PMID:23962110 RGD:38456007 NCBI chr  X:42,331,229...42,362,841
Ensembl chr  X:42,344,108...42,350,758
JBrowse link
G FYN FYN proto-oncogene, Src family tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr12:68,105,060...68,316,630
Ensembl chr12:68,075,184...68,316,541
JBrowse link
G GATA3 GATA binding protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr 2:28,068,143...28,098,445
Ensembl chr 2:28,069,051...28,087,760
JBrowse link
G GPR183 G protein-coupled receptor 183 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr22:49,332,665...49,347,721
Ensembl chr22:49,333,188...49,347,593
JBrowse link
G HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr14:39,498,805...39,509,034
Ensembl chr14:39,500,897...39,508,952
JBrowse link
G ICOS inducible T cell costimulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr37:12,663,839...12,735,266
Ensembl chr37:12,670,999...12,733,458
JBrowse link
G IFNG interferon gamma treatment ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:8800741 PMID:23962110 RGD:10755707 NCBI chr10:10,406,866...10,411,698
Ensembl chr10:10,406,867...10,411,698
JBrowse link
G IKZF2 IKAROS family zinc finger 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr37:20,508,647...20,662,549
Ensembl chr37:20,516,239...20,661,298
JBrowse link
G IL10 interleukin 10 ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:8704212 PMID:23962110 RGD:11049460 NCBI chr 7:5,933,285...5,937,057
Ensembl chr 7:5,933,285...5,937,057
JBrowse link
G IL2 interleukin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23962110 NCBI chr19:17,750,780...17,756,394
Ensembl chr19:17,750,780...17,756,394
JBrowse link
G IL4 interleukin 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23962110 NCBI chr11:20,972,693...20,981,539
Ensembl chr11:20,972,690...20,981,534
JBrowse link
G IL5 interleukin 5 disease_progression ISO protein:increased expression:serum RGD PMID:16425276 RGD:11354942 NCBI chr11:20,825,469...20,827,269
Ensembl chr11:20,825,469...20,827,269
JBrowse link
G IL6 interleukin 6 ISO protein:increased expression:serum (human) RGD PMID:10374863 RGD:11060275 NCBI chr14:36,474,268...36,478,519
Ensembl chr14:36,473,394...36,478,519
JBrowse link
G IRF4 interferon regulatory factor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr35:760,367...782,314
Ensembl chr35:767,011...781,339
JBrowse link
G JAK3 Janus kinase 3 ISO DNA:missense mutations: :p.L156P, p.R172Q, p.E183G (human) RGD PMID:21821710 RGD:11531131 NCBI chr20:45,051,135...45,068,445
Ensembl chr20:45,050,526...45,072,805
JBrowse link
G MYB MYB proto-oncogene, transcription factor disease_progression ISO mRNA:splice variants:CD4+ T cell: RGD PMID:27307595 RGD:11532670 NCBI chr 1:27,908,309...27,991,984
Ensembl chr 1:27,908,364...27,991,969
JBrowse link
G NOTCH1 notch receptor 1 ISO DNA:mutations:multiple (human) RGD PMID:16707600 RGD:1580759 NCBI chr 9:48,975,972...49,018,985
Ensembl chr 9:48,974,757...49,017,277
JBrowse link
G NRAS NRAS proto-oncogene, GTPase disease_progression ISO RGD PMID:21586752 RGD:11535055 NCBI chr17:52,411,733...52,418,788
Ensembl chr17:52,411,733...52,418,788
JBrowse link
G PLCG1 phospholipase C gamma 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr24:29,198,536...29,213,899
Ensembl chr24:29,198,556...29,214,714
JBrowse link
G PRKCB protein kinase C beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr 6:21,742,970...22,064,360
Ensembl chr 6:21,742,973...22,065,185
JBrowse link
G STAT3 signal transducer and activator of transcription 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24090995 NCBI chr 9:20,539,660...20,614,631
Ensembl chr 9:20,539,697...20,612,672
JBrowse link
G TAL2 TAL bHLH transcription factor 2 ISO RGD PMID:1763056 RGD:1599285 NCBI chr11:61,425,927...61,484,525
Ensembl chr11:61,456,727...61,482,348
JBrowse link
G TERF2 telomeric repeat binding factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17643074 NCBI chr 5:80,278,224...80,305,315
Ensembl chr 5:80,277,505...80,306,342
JBrowse link
G TLX1 T cell leukemia homeobox 1 ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:1683261 PMID:1717256 RGD:1599439 NCBI chr28:13,807,428...13,813,875
Ensembl chr28:13,807,720...13,813,849
JBrowse link
G TNFSF8 TNF superfamily member 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:9058727 NCBI chr11:68,979,498...69,006,898
Ensembl chr11:68,982,360...69,007,355
JBrowse link
G TP73 tumor protein p73 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr 5:58,194,385...58,241,159
Ensembl chr 5:58,187,826...58,240,839
JBrowse link
G VAV1 vav guanine nucleotide exchange factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr20:53,482,239...53,532,399
Ensembl chr20:53,482,498...53,531,296
JBrowse link
alpha-thalassemia myelodysplasia syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATRX ATRX chromatin remodeler ISO OMIM NCBI chr  X:59,772,067...60,107,016
Ensembl chr  X:59,774,585...60,106,980
JBrowse link
AMED SYNDROME, DIGENIC term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide ISO OMIM NCBI chr32:21,249,459...21,261,130
Ensembl chr32:21,249,739...21,265,048
JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member ISO ClinVar Annotator: match by term: BONE MARROW FAILURE SYNDROME 7, DIGENIC ClinVar PMID:2987944 PMID:4065146 PMID:6650498 PMID:7180842 PMID:7593603 PMID:8903321 PMID:10627091 PMID:10780266 PMID:15654505 PMID:16046871 PMID:16440063 PMID:17885622 PMID:18056758 PMID:20010786 PMID:33355142 NCBI chr26:9,319,109...9,361,021 JBrowse link
anaplastic large cell lymphoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALK ALK receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16151469 PMID:19503098 PMID:21345110 PMID:22155737 PMID:22920921 PMID:22968692 NCBI chr17:23,010,308...23,688,841
Ensembl chr17:23,010,308...23,688,841
JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17157164 NCBI chr 8:70,091,203...70,096,107
Ensembl chr 8:70,092,217...70,095,243
JBrowse link
G IRF4 interferon regulatory factor 4 ISO DNA:translocation RGD PMID:18987657 RGD:11526155 NCBI chr35:760,367...782,314
Ensembl chr35:767,011...781,339
JBrowse link
G JUNB JunB proto-oncogene, AP-1 transcription factor subunit ISO RGD PMID:12145210 RGD:1549449 NCBI chr20:49,358,904...49,360,746
Ensembl chr20:49,359,399...49,360,442
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:17261581 NCBI chr18:51,550,003...51,558,861
Ensembl chr18:51,550,040...51,558,875
JBrowse link
G STAT3 signal transducer and activator of transcription 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22155737 NCBI chr 9:20,539,660...20,614,631
Ensembl chr 9:20,539,697...20,612,672
JBrowse link
G TNFRSF8 TNF receptor superfamily member 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10908157 PMID:17261581 NCBI chr 2:84,185,445...84,225,986
Ensembl chr 2:84,186,961...84,232,675
JBrowse link
G TWIST1 twist family bHLH transcription factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22155737
Anemia, Refractory, with Excess of Blasts term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BIRC5 baculoviral IAP repeat containing 5 ISO RGD PMID:18426652 RGD:11038658 NCBI chr 9:2,930,308...2,959,307 JBrowse link
G C3 complement C3 disease_progression ISO RGD PMID:9741227 RGD:11041158 NCBI chr20:53,566,226...53,598,365
Ensembl chr20:53,566,261...53,598,761
JBrowse link
G CFB complement factor B disease_progression ISO RGD PMID:9741227 RGD:11041158 NCBI chr12:1,400,143...1,406,267 JBrowse link
G TERT telomerase reverse transcriptase ISO RGD PMID:18426652 RGD:11038658 NCBI chr34:11,288,622...11,307,790
Ensembl chr34:11,288,622...11,307,951
JBrowse link
G TET2 tet methylcytosine dioxygenase 2 disease_progression ISO RGD PMID:25200248 RGD:11038682 NCBI chr32:26,021,745...26,145,109
Ensembl chr32:26,059,693...26,143,536
JBrowse link
atypical chronic myeloid leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FGFR1 fibroblast growth factor receptor 1 ISO RGD PMID:15050920 RGD:11352668 NCBI chr16:27,029,902...27,080,514
Ensembl chr16:27,031,588...27,078,261
JBrowse link
G SETBP1 SET binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23222956 NCBI chr 7:46,020,892...46,378,867
Ensembl chr 7:46,020,889...46,378,005
JBrowse link
autosomal dominant sideroblastic anemia 4 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSPA9 heat shock protein family A (Hsp70) member 9 ISO OMIM NCBI chr11:26,122,917...26,142,458
Ensembl chr11:26,121,499...26,142,434
JBrowse link
autosomal recessive pyridoxine-refractory sideroblastic anemia 2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GLRX5 glutaredoxin 5 ISO CTD Direct Evidence: marker/mechanism CTD NCBI chr 8:64,383,203...64,392,886
Ensembl chr 8:64,383,227...64,383,841
JBrowse link
G SLC25A38 solute carrier family 25 member 38 ISO OMIM NCBI chr23:9,031,984...9,045,781
Ensembl chr23:9,032,000...9,045,788
JBrowse link
autosomal recessive pyridoxine-refractory sideroblastic anemia 3 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GLRX5 glutaredoxin 5 ISO OMIM NCBI chr 8:64,383,203...64,392,886
Ensembl chr 8:64,383,227...64,383,841
JBrowse link
Autosomal Sideroblastic Anemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARSA arylsulfatase A ISO ClinVar Annotator: match by term: Autosomal recessive sideroblastic anemia ClinVar PMID:25741868 NCBI chr10:16,691,927...16,694,346
Ensembl chr10:16,691,758...16,695,398
JBrowse link
B-Cell Chronic Lymphocytic Leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCG2 ATP binding cassette subfamily G member 2 susceptibility ISO DNA:SNPs,haplotype: :rs1481012,rs2231142(human) RGD PMID:21918980 RGD:11080977 NCBI chr32:11,443,778...11,517,674
Ensembl chr32:11,443,780...11,517,674
JBrowse link
G ACOXL acyl-CoA oxidase like ISO CTD Direct Evidence: marker/mechanism CTD PMID:23770605 NCBI chr17:35,269,824...35,617,068
Ensembl chr17:35,269,501...35,617,335
JBrowse link
G AICDA activation induced cytidine deaminase disease_progression ISO RGD PMID:21133730 RGD:11039455 NCBI chr27:37,064,107...37,073,791
Ensembl chr27:37,064,080...37,073,789
JBrowse link
G APOE apolipoprotein E disease_progression ISO RGD PMID:18784741 RGD:11040549 NCBI chr 1:110,525,717...110,528,534
Ensembl chr 1:110,525,722...110,528,440
JBrowse link
G ATM ATM serine/threonine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:17968022 NCBI chr 5:24,180,129...24,297,207
Ensembl chr 5:24,182,135...24,297,207
JBrowse link
G BCL11A BAF chromatin remodeling complex subunit BCL11A ISO DNA:translocation:5' utr: (human) RGD PMID:11719382 RGD:11100004 NCBI chr10:60,589,298...60,691,997
Ensembl chr10:60,589,708...60,689,073
JBrowse link
G BCL2 BCL2 apoptosis regulator severity
no_association
treatment
ISO protein:increased expression:B cell (human)
CTD Direct Evidence: marker/mechanism
DNA:snp:promoter:g.-938C>A (human)
RGD
CTD
PMID:16960146 PMID:17296974 PMID:17959858 PMID:20001236 PMID:21750559 PMID:23770605 RGD:11522735 RGD:11526104 RGD:11526105 RGD:11526110 NCBI chr 1:13,733,849...13,900,653
Ensembl chr 1:13,731,406...13,900,658
JBrowse link
G BMF Bcl2 modifying factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:23770605 NCBI chr30:7,301,000...7,321,949
Ensembl chr30:7,274,174...7,322,034
JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase ISO ClinVar Annotator: match by term: B-cell chronic lymphocytic leukemia
ClinVar Annotator: match by term: Leukemia, B-cell, chronic
ClinVar PMID:12068308 PMID:14612909 PMID:14679157 PMID:14688025 PMID:17096326 PMID:17119447 PMID:17311103 PMID:18368129 PMID:18794803 PMID:19383316 PMID:19537845 PMID:19913317 PMID:20350999 PMID:20619739 PMID:21129611 PMID:22310681 PMID:23352452 PMID:24033266 PMID:25157968 PMID:26619011 PMID:28492532 PMID:29595366 NCBI chr16:8,222,909...8,318,179
Ensembl chr16:8,222,907...8,317,906
JBrowse link
G BTK Bruton tyrosine kinase treatment ISO RGD PMID:23045577 RGD:11040699 NCBI chr  X:75,270,952...75,302,663
Ensembl chr  X:75,270,979...75,302,562
JBrowse link
G CBL Cbl proto-oncogene severity ISO mRNA,protein:increased expression:CD5+ B cell:
DNA:hypophosphorylation:CD5+ B cell:
RGD PMID:17804547 RGD:11038803 NCBI chr 5:14,600,409...14,676,974
Ensembl chr 5:14,607,013...14,676,956
JBrowse link
G CCDC50 coiled-coil domain containing 50 ISO RGD PMID:19641524 RGD:9685139 NCBI chr34:23,168,594...23,243,221
Ensembl chr34:23,168,525...23,258,497
JBrowse link
G CD40 CD40 molecule ISO RGD PMID:20616215 RGD:5490532 NCBI chr24:33,352,992...33,383,488
Ensembl chr24:33,372,930...33,383,301
JBrowse link
G CD40LG CD40 ligand ISO mouse-human chimeric gene in human RGD PMID:20882050 RGD:11352235 NCBI chr  X:107,001,421...107,023,007
Ensembl chr  X:107,010,890...107,023,006
JBrowse link
G CD5 CD5 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:18006695 NCBI chr18:55,216,415...55,235,567
Ensembl chr18:55,217,276...55,235,405
JBrowse link
G CD79B CD79b molecule ISO protein:decreased expression:B lymphocyte, cell surface (human) RGD PMID:9269755 RGD:11250403 NCBI chr 9:11,834,230...11,844,946
Ensembl chr 9:11,842,190...11,844,843
JBrowse link
G CD86 CD86 molecule severity ISO protein:increased expression:peripheral blood mononuclear cell (human) RGD PMID:25179679 RGD:11354969 NCBI chr33:25,256,267...25,318,855
Ensembl chr33:25,256,267...25,318,087
JBrowse link
G CPEB1 cytoplasmic polyadenylation element binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20062064 NCBI chr 3:54,405,140...54,499,614
Ensembl chr 3:54,405,717...54,500,221
JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 ISO protein:increased expression:T cell RGD PMID:15914560 PMID:16094420 RGD:11344923 RGD:11352246 NCBI chr37:12,647,712...12,653,874
Ensembl chr37:12,634,563...12,653,874
JBrowse link
G DKC1 dyskerin pseudouridine synthase 1 ISO RGD PMID:18077792 RGD:11251735 NCBI chr  X:122,838,787...122,850,870
Ensembl chr  X:122,838,645...122,850,884
JBrowse link
G DNMT3B DNA methyltransferase 3 beta ISO mRNA:decreased expression: B cell RGD PMID:15467427 RGD:9589146 NCBI chr24:22,096,386...22,123,378
Ensembl chr24:22,096,349...22,122,900
JBrowse link
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit severity ISO DNA:SNP: :p.K751Q (rs13181) (human) RGD PMID:19484764 PMID:22739018 RGD:11252203 RGD:11252204 NCBI chr 1:110,173,781...110,191,612
Ensembl chr 1:110,173,715...110,190,125
JBrowse link
G FARP2 FERM, ARH/RhoGEF and pleckstrin domain protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20062064 NCBI chr25:51,331,876...51,425,754
Ensembl chr25:51,332,409...51,425,449
JBrowse link
G FAS Fas cell surface death receptor disease_progression ISO RGD PMID:12901972 RGD:11049461 NCBI chr26:38,738,811...38,763,298
Ensembl chr26:38,737,611...38,763,321
JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 ISO ClinVar Annotator: match by term: B-cell chronic lymphocytic leukemia ClinVar PMID:25741868 PMID:26619011 NCBI chr15:50,187,579...50,417,188
Ensembl chr15:50,189,240...50,417,195
JBrowse link
G GNAS GNAS complex locus disease_progression ISO DNA:polymorphism:393T>C (human) RGD PMID:17020971 RGD:1601379 NCBI chr24:43,643,409...43,658,641
Ensembl chr24:43,643,405...43,658,657
JBrowse link
G HRAS HRas proto-oncogene, GTPase ISO ClinVar Annotator: match by term: B-cell chronic lymphocytic leukemia
ClinVar Annotator: match by term: Leukemia, B-cell, chronic
ClinVar PMID:12835555 PMID:16329078 PMID:16372351 PMID:16835863 PMID:17211612 PMID:17384584 PMID:18042262 PMID:19213030 PMID:19255327 PMID:19773371 PMID:20859122 PMID:21438134 PMID:21495179 PMID:21850009 PMID:22256804 PMID:22499344 PMID:22683711 PMID:22726224 PMID:23093928 PMID:23096712 PMID:23406027 PMID:23429430 PMID:23884457 PMID:24006476 PMID:24033266 PMID:24129065 PMID:24224811 PMID:24390138 PMID:25157968 PMID:25326635 PMID:25741868 PMID:26619011 PMID:28492532 PMID:29493581 PMID:31775759 PMID:168335863 NCBI chr18:25,642,844...25,644,717
Ensembl chr18:25,642,844...25,644,717
JBrowse link
G ICAM1 intercellular adhesion molecule 1 severity ISO RGD PMID:7658704 RGD:11354983 NCBI chr20:50,818,715...50,827,914
Ensembl chr20:50,818,715...50,827,914
JBrowse link
G IFNG interferon gamma susceptibility ISO DNA:polymorphism: :847A>T(human) RGD PMID:19757192 RGD:10755703 NCBI chr10:10,406,866...10,411,698
Ensembl chr10:10,406,867...10,411,698
JBrowse link
G IL10 interleukin 10 disease_progression
no_association
ISO protein:increased expression:serum
DNA:SNPs: :rs1800890, rs4072227, rs17015865 (human)
DNA:SNPs: :multiple
RGD PMID:10638947 PMID:19573080 PMID:22945689 RGD:11041895 RGD:11049165 RGD:11049174 NCBI chr 7:5,933,285...5,937,057
Ensembl chr 7:5,933,285...5,937,057
JBrowse link
G IL19 interleukin 19 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18006695 NCBI chr 7:6,000,994...6,006,959
Ensembl chr 7:6,000,907...6,006,870
JBrowse link
G IL1A interleukin 1 alpha ISO RGD PMID:19074885 RGD:11051968 NCBI chr17:36,969,581...36,979,445
Ensembl chr17:36,970,573...36,979,435
JBrowse link
G IL1B interleukin 1 beta severity ISO DNA:SNP:promoter:-511C>T (human)
protein:decreased expression:plasma:
RGD PMID:10870116 PMID:18271063 RGD:11051967 RGD:11522755 NCBI chr17:37,019,329...37,033,388
Ensembl chr17:37,019,329...37,024,458
JBrowse link
G IL1RN interleukin 1 receptor antagonist ISO protein:decreased expression:plasma: RGD PMID:10870116 RGD:11522755 NCBI chr17:37,236,690...37,250,424
Ensembl chr17:37,212,751...37,249,329
JBrowse link
G IL6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:plasma:
CTD
RGD
PMID:10870116 PMID:18006695 RGD:11522755 NCBI chr14:36,474,268...36,478,519
Ensembl chr14:36,473,394...36,478,519
JBrowse link
G IRF4 interferon regulatory factor 4 disease_progression ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:12079517 PMID:12393648 PMID:18758461 RGD:11526160 RGD:11530024 NCBI chr35:760,367...782,314
Ensembl chr35:767,011...781,339
JBrowse link
G ITGA4 integrin subunit alpha 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21093051 NCBI chr36:24,670,464...24,686,719
Ensembl chr36:24,653,408...24,729,057
JBrowse link
G KRAS KRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: B-cell chronic lymphocytic leukemia ClinVar PMID:2278970 PMID:3122217 PMID:12460918 PMID:15696205 PMID:16361624 PMID:16434492 PMID:16618717 PMID:18316791 PMID:18794081 PMID:19075190 PMID:19114683 PMID:19679400 PMID:20921462 PMID:20921465 PMID:21228335 PMID:22407852 PMID:22722830 PMID:23325582 PMID:25157968 PMID:26619011 NCBI chr27:22,261,753...22,296,704
Ensembl chr27:22,257,941...22,293,369
JBrowse link
G LEF1 lymphoid enhancer binding factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23770605 NCBI chr32:28,516,002...28,633,759
Ensembl chr32:28,517,108...28,634,019
JBrowse link
G LOC100683403 NKG2-A/NKG2-B type II integral membrane protein-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:18006695 NCBI chr27:35,307,892...35,374,397 JBrowse link
G LOC478984 low affinity immunoglobulin gamma Fc region receptor III no_association ISO DNA:SNP:exon:p.F158V (rs396991) (human) RGD PMID:14563637 RGD:11352260 NCBI chr38:21,054,870...21,060,948 JBrowse link
G LRRC56 leucine rich repeat containing 56 ISO ClinVar Annotator: match by term: B-cell chronic lymphocytic leukemia
ClinVar Annotator: match by term: Leukemia, B-cell, chronic
ClinVar PMID:12835555 PMID:16329078 PMID:16372351 PMID:16835863 PMID:17211612 PMID:17384584 PMID:18042262 PMID:19213030 PMID:19255327 PMID:19773371 PMID:20859122 PMID:21438134 PMID:21495179 PMID:21850009 PMID:22256804 PMID:22499344 PMID:22683711 PMID:22726224 PMID:23093928 PMID:23096712 PMID:23406027 PMID:23429430 PMID:23884457 PMID:24006476 PMID:24033266 PMID:24129065 PMID:24224811 PMID:24390138 PMID:25157968 PMID:25326635 PMID:25741868 PMID:26619011 PMID:28492532 PMID:29493581 PMID:31775759 PMID:168335863 NCBI chr18:25,647,024...25,662,646
Ensembl chr18:25,647,882...25,664,220
JBrowse link
G MIR143 microRNA mir-143 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17892514 NCBI chr 4:59,534,535...59,534,589
Ensembl chr 4:59,534,535...59,534,594
JBrowse link
G MIR145 microRNA mir-145 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17892514 NCBI chr 4:59,533,128...59,533,210
Ensembl chr 4:59,533,128...59,533,210
JBrowse link
G MS4A1 membrane spanning 4-domains A1 ISO RGD PMID:19911856 RGD:2316994 NCBI chr21:50,722,142...50,734,934
Ensembl chr21:50,722,041...50,733,704
JBrowse link
G MTHFR methylenetetrahydrofolate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16706930 NCBI chr 2:84,445,526...84,457,435
Ensembl chr 2:84,380,919...84,536,818
JBrowse link
G NRAS NRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: B-cell chronic lymphocytic leukemia ClinVar PMID:1654209 PMID:2278970 PMID:2674680 PMID:3122217 PMID:6587382 PMID:8120410 PMID:10821536 PMID:12460918 PMID:12727991 PMID:14508525 PMID:15899789 PMID:16273091 PMID:16291983 PMID:16434492 PMID:17699718 PMID:18390968 PMID:18633438 PMID:18668139 PMID:18948947 PMID:19075190 PMID:19657110 PMID:19880792 PMID:20130576 PMID:20149136 PMID:20179705 PMID:20406486 PMID:20619739 PMID:20736745 PMID:21107323 PMID:21305640 PMID:21576590 PMID:21729679 PMID:21829508 PMID:22407852 PMID:22499344 PMID:22718121 PMID:22761467 PMID:22773810 PMID:23076151 PMID:23392294 PMID:23400451 PMID:23414587 PMID:23515407 PMID:23538902 PMID:23569304 PMID:23614898 PMID:24006476 PMID:24033266 PMID:24148783 PMID:24370118 PMID:24671188 PMID:25157968 PMID:25348872 PMID:25695684 PMID:26619011 PMID:26821351 PMID:27050078 PMID:28492532 PMID:28780248 NCBI chr17:52,411,733...52,418,788
Ensembl chr17:52,411,733...52,418,788
JBrowse link
G P2RX7 purinergic receptor P2X 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11003599 NCBI chr26:7,928,863...7,983,956
Ensembl chr26:7,940,985...7,983,740
JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 severity ISO protein:increased expression:B cell (human) RGD PMID:12673718 RGD:11541127 NCBI chr 9:12,166,124...12,219,553
Ensembl chr 9:12,166,775...12,219,778
JBrowse link
G PLCG2 phospholipase C gamma 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27542411 NCBI chr 5:70,054,683...70,233,459
Ensembl chr 5:70,059,255...70,207,049
JBrowse link
G PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23770605 NCBI chr 1:16,469,793...16,472,910
Ensembl chr 1:16,469,793...16,472,910
JBrowse link
G POLB DNA polymerase beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:18006695 NCBI chr16:23,306,359...23,335,352
Ensembl chr16:23,306,367...23,335,322
JBrowse link
G PPP2R5C protein phosphatase 2 regulatory subunit B'gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:16038780 NCBI chr 8:69,846,311...69,969,409
Ensembl chr 8:69,846,446...69,967,578
JBrowse link
G PRAME PRAME nuclear receptor transcriptional regulator ISO protein:increased expression:mononuclear cell (human) RGD PMID:16620968 RGD:11535021 NCBI chr26:27,124,901...27,137,772
Ensembl chr26:27,124,902...27,136,112
JBrowse link
G PRKD2 protein kinase D2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18758461 NCBI chr 1:109,206,400...109,241,529
Ensembl chr 1:109,207,067...109,330,007
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16314473 NCBI chr 7:19,668,079...19,674,903
Ensembl chr 7:19,668,082...19,674,903
JBrowse link
G QPCT glutaminyl-peptide cyclotransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23770605 NCBI chr17:29,700,422...29,741,652
Ensembl chr17:29,716,378...29,741,221
JBrowse link
G RBL2 RB transcriptional corepressor like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16038780 NCBI chr 2:62,263,974...62,315,371
Ensembl chr 2:62,265,293...62,315,425
JBrowse link
G SF3B1 splicing factor 3b subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22158541 NCBI chr37:6,922,150...6,962,474
Ensembl chr37:6,924,047...6,962,896
JBrowse link
G SP140 SP140 nuclear body protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:18758461 NCBI chr25:42,459,013...42,527,141
Ensembl chr25:42,459,084...42,527,093
JBrowse link
G TERT telomerase reverse transcriptase disease_progression ISO RGD PMID:17344921 RGD:11038662 NCBI chr34:11,288,622...11,307,790
Ensembl chr34:11,288,622...11,307,951
JBrowse link
G TFRC transferrin receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:16904380 NCBI chr33:29,206,024...29,237,221
Ensembl chr33:29,208,609...29,238,242
JBrowse link
G THBD thrombomodulin ISO RGD PMID:21812019 RGD:5685033 NCBI chr24:599,773...601,649
Ensembl chr24:599,773...601,649
JBrowse link
G TNF tumor necrosis factor disease_progression ISO protein:increased expression:bone marrow, blood, lymphocyte RGD PMID:12010662 PMID:22945689 RGD:10449463 RGD:11041895 NCBI chr12:1,074,561...1,076,425
Ensembl chr12:1,074,552...1,076,425
JBrowse link
G TNFRSF11A TNF receptor superfamily member 11a ISO CTD Direct Evidence: marker/mechanism CTD PMID:16270354 NCBI chr 1:14,504,595...14,555,956
Ensembl chr 1:14,503,033...14,556,041
JBrowse link
G TNFSF11 TNF superfamily member 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16270354 NCBI chr22:8,226,931...8,257,926
Ensembl chr22:8,227,555...8,258,645
JBrowse link
G TNFSF13 TNF superfamily member 13 ISO protein:increased expression:serum RGD PMID:15488762 RGD:1549466 NCBI chr 5:32,482,723...32,484,790
Ensembl chr 5:32,482,723...32,484,789
JBrowse link
G TNFSF8 TNF superfamily member 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:9058727 NCBI chr11:68,979,498...69,006,898
Ensembl chr11:68,982,360...69,007,355
JBrowse link
G TOPBP1 DNA topoisomerase II binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18006695 NCBI chr23:30,517,172...30,578,664
Ensembl chr23:30,516,125...30,578,108
JBrowse link
G TP53 tumor protein p53 disease_progression ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Leukemia, B-cell, chronic
ClinVar Annotator: match by term: B-cell chronic lymphocytic leukemia
ClinVar Annotator: match by term: Chronic lymphatic leukemia
DNA:deletion: :
CTD
ClinVar
RGD
PMID:1359493 PMID:1565143 PMID:1565144 PMID:1631137 PMID:1679237 PMID:1683921 PMID:1978757 PMID:2046748 PMID:2531845 PMID:2554494 PMID:2826609 PMID:7651740 PMID:7732013 PMID:7791795 PMID:7887414 PMID:8023157 PMID:8062826 PMID:8099841 PMID:8164043 PMID:8242631 PMID:8423216 PMID:8425176 PMID:8479749 PMID:8527048 PMID:8718514 PMID:8825920 PMID:9242456 PMID:9290701 PMID:9364015 PMID:9407971 PMID:9546439 PMID:9569050 PMID:9598730 PMID:9627118 PMID:9632751 PMID:9825943 PMID:9839505 PMID:10064694 PMID:10411893 PMID:10519380 PMID:10761705 PMID:10797439 PMID:10864200 PMID:10867151 PMID:11051239 PMID:11139324 PMID:11180592 PMID:11370630 PMID:11429705 PMID:11479205 PMID:11593407 PMID:11782540 PMID:11793474 PMID:11896595 PMID:11920959 PMID:12007217 PMID:12406399 PMID:12672316 PMID:12700230 PMID:12726864 PMID:12826609 PMID:12917626 PMID:14559903 PMID:14584079 PMID:14673037 PMID:15004724 PMID:15017592 PMID:15381368 PMID:15390294 PMID:15607980 PMID:15607981 PMID:15722483 PMID:15825182 PMID:15925506 PMID:15951970 PMID:16337994 PMID:16401470 PMID:16439677 PMID:16489069 PMID:16682957 PMID:16818505 PMID:16827139 PMID:16861262 PMID:17390010 PMID:17417627 PMID:17427234 PMID:17540308 PMID:17572079 PMID:17606709 PMID:17636407 PMID:17724467 PMID:18511570 PMID:18685109 PMID:19147582 PMID:19367569 PMID:19378321 PMID:19405127 PMID:19556618 PMID:19681600 PMID:19850740 PMID:19930417 PMID:20013323 PMID:20113312 PMID:20128691 PMID:20308654 PMID:20407015 PMID:20505364 PMID:20516128 PMID:20522432 PMID:20693561 PMID:20805372 PMID:20878954 PMID:21056685 PMID:21059199 PMID:21115975 PMID:21159183 PMID:21187651 PMID:21305319 PMID:21343334 PMID:21483000 PMID:21484931 PMID:21514416 PMID:21519010 PMID:21535297 PMID:21552135 PMID:21601526 PMID:21761402 PMID:22006311 PMID:22110706 PMID:22186996 PMID:22198284 PMID:22233476 PMID:22265402 PMID:22713868 PMID:22811390 PMID:22844452 PMID:22866089 PMID:22899716 PMID:22915647 PMID:22919068 PMID:23161690 PMID:23172776 PMID:23246812 PMID:23263379 PMID:23265383 PMID:23538418 PMID:23667202 PMID:23713777 PMID:23792586 PMID:23894400 PMID:23950206 PMID:24033266 PMID:24038938 PMID:24381225 PMID:24487413 PMID:24501221 PMID:24573247 PMID:24590827 PMID:24603336 PMID:24641375 PMID:24651012 PMID:24651015 PMID:24677579 PMID:24744791 PMID:24766216 PMID:24810334 PMID:25157968 PMID:25293557 PMID:25294809 PMID:25339994 PMID:25504633 PMID:25525159 PMID:25584008 PMID:25584637 PMID:25634208 PMID:25691460 PMID:25741868 PMID:25787918 PMID:25896519 PMID:25925845 PMID:25927356 PMID:25945745 PMID:25952993 PMID:26014290 PMID:26024390 PMID:26230955 PMID:26425688 PMID:26467025 PMID:26534844 PMID:26585234 PMID:26619011 PMID:26681312 PMID:26781615 PMID:26787237 PMID:26822237 PMID:26845104 PMID:27179933 PMID:27276561 PMID:27276934 PMID:27374712 PMID:27463065 PMID:27493922 PMID:27501770 PMID:27523101 PMID:27680515 PMID:27683180 PMID:27714481 PMID:27724982 PMID:27873457 PMID:27895058 PMID:27959731 PMID:28152038 PMID:28369373 PMID:28453743 PMID:28472496 PMID:28476805 PMID:28492532 PMID:28724667 PMID:28861920 PMID:29025599 PMID:29324801 PMID:29470806 PMID:29478780 PMID:29489754 PMID:29752822 PMID:29979965 PMID:30076369 PMID:30224644 PMID:30327374 PMID:30816478 PMID:30840781 PMID:31300551 PMID:31775759 PMID:32000721 PMID:32295079 RGD:11075074 NCBI chr 5:32,561,406...32,565,149
Ensembl chr 5:32,560,598...32,574,109
JBrowse link
G VDR vitamin D receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:12446453 NCBI chr27:6,852,915...6,909,466
Ensembl chr27:6,852,723...6,909,470
JBrowse link
G XPO1 exportin 1 ISO ClinVar Annotator: match by term: B-cell chronic lymphocytic leukemia ClinVar PMID:26619011 NCBI chr10:61,541,647...61,588,397
Ensembl chr10:61,542,211...61,585,054
JBrowse link
G XRCC1 X-ray repair cross complementing 1 no_association
severity
ISO DNA:SNP: :p.R194W (rs1799782), p.R280H (25489) (human)
DNA:SNP: :p.R399Q (rs25487) (human)
RGD PMID:19484764 RGD:11252204 NCBI chr 1:111,548,719...111,571,816
Ensembl chr 1:111,548,719...111,571,816
JBrowse link
B-Cell CLL/Lymphoma 2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL2 BCL2 apoptosis regulator ISO OMIM NCBI chr 1:13,733,849...13,900,653
Ensembl chr 1:13,731,406...13,900,658
JBrowse link
B-cell lymphoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCG2 ATP binding cassette subfamily G member 2 susceptibility ISO DNA:SNP: :rs6857600(human) RGD PMID:21918980 RGD:11080977 NCBI chr32:11,443,778...11,517,674
Ensembl chr32:11,443,780...11,517,674
JBrowse link
G AICDA activation induced cytidine deaminase ISO RGD PMID:17251349 RGD:11039449 NCBI chr27:37,064,107...37,073,791
Ensembl chr27:37,064,080...37,073,789
JBrowse link
G BCL2L2 BCL2 like 2 disease_progression ISO RGD PMID:28094768 RGD:14394511 NCBI chr 8:3,569,335...3,573,922
Ensembl chr 8:3,569,399...3,586,070
JBrowse link
G BCL6 BCL6 transcription repressor ISO diffuse large B-cell lymphoma DNA:translocation:promoter,CDS:t(3;16)(q27;p11) results in IL21R promoter fused to BCL6 coding region RGD PMID:11821949 RGD:1600111 NCBI chr34:20,112,302...20,135,705
Ensembl chr34:20,113,322...20,124,704
JBrowse link
G BRD2 bromodomain containing 2 ISO RGD PMID:14563639 RGD:9586345 NCBI chr12:2,534,034...2,546,029
Ensembl chr12:2,534,034...2,546,029
JBrowse link
G BTK Bruton tyrosine kinase treatment ISO human cell in a mouse model RGD PMID:25662332 PMID:28348046 RGD:11040764 RGD:124713554 NCBI chr  X:75,270,952...75,302,663
Ensembl chr  X:75,270,979...75,302,562
JBrowse link
G CBX7 chromobox 7 ISO RGD PMID:17374722 RGD:11352707 NCBI chr10:25,876,022...25,896,284
Ensembl chr10:25,876,016...25,893,501
JBrowse link
G CD40 CD40 molecule ISO RGD PMID:20616215 RGD:5490532 NCBI chr24:33,352,992...33,383,488
Ensembl chr24:33,372,930...33,383,301
JBrowse link
G CSF2 colony stimulating factor 2 treatment ISO RGD PMID:8469286 RGD:10450244 NCBI chr11:20,342,880...20,346,959
Ensembl chr11:20,344,648...20,346,959
JBrowse link
G CSF3 colony stimulating factor 3 ISO CTD Direct Evidence: therapeutic CTD PMID:11042651 NCBI chr 9:22,529,643...22,532,326
Ensembl chr 9:22,530,698...22,533,108
JBrowse link
G EAF2 ELL associated factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20564326 NCBI chr33:25,113,348...25,147,064
Ensembl chr33:25,112,570...25,146,692
JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit severity
treatment
ISO RGD PMID:23982173 PMID:29456795 RGD:10755356 RGD:126781726 NCBI chr16:1,926,443...1,991,995
Ensembl chr16:1,925,956...1,991,838
JBrowse link
G IL21R interleukin 21 receptor ISO diffuse large B-cell lymphoma DNA:translocation:promoter,CDS:t(3;16)(q27;p11) results in IL21R promoter fused to BCL6 coding region RGD PMID:11821949 RGD:1600111 NCBI chr 6:19,181,846...19,217,915
Ensembl chr 6:19,182,071...19,217,931
JBrowse link
G JAK3 Janus kinase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24837469 NCBI chr20:45,051,135...45,068,445
Ensembl chr20:45,050,526...45,072,805
JBrowse link
G KAT5 lysine acetyltransferase 5 severity ISO RGD PMID:17728759 RGD:9588481 NCBI chr18:51,499,615...51,507,434
Ensembl chr18:51,499,938...51,576,699