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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Arterial Occlusive Diseases
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Accession:DOID:9006474 term browser browse the term
Definition:Pathological processes which result in the partial or complete obstruction of ARTERIES. They are characterized by greatly reduced or absence of blood flow through these vessels. They are also known as arterial insufficiency.
Synonyms:exact_synonym: Arterial Obstructive Diseases;   arterial obstructive disease;   arterial occlusive disease
 related_synonym: ANTICHYMOTRYPSIN ISEHARA 1
 primary_id: MESH:D001157
 alt_id: RDO:0004908
For additional species annotation, visit the Alliance of Genome Resources.

show annotations for term's descendants           Sort by:
 
Arterial Occlusive Diseases term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itgb3 integrin subunit beta 3 IMP neointima RGD PMID:16793666 RGD:4990460 NCBI chr10:92,667,869...92,783,413
Ensembl chr10:92,667,869...92,783,410 		JBrowse link
G LOC299277 similar to serine (or cysteine) peptidase inhibitor, clade A, member 3B ISO ClinVar Annotator: match by term: ANTICHYMOTRYPSIN ISEHARA 1 ClinVar PMID:1618300 PMID:9040504 PMID:11289720 PMID:25741868 NCBI chr 6:127,871,895...127,888,287
Ensembl chr 6:127,872,666...127,886,540 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO DNA:SNP: :677C>T (human) RGD PMID:10477457 RGD:10449401 NCBI chr 5:164,844,642...164,864,360
Ensembl chr 5:164,845,925...164,860,910 		JBrowse link
G Plat plasminogen activator, tissue type ISO CTD Direct Evidence: therapeutic CTD PMID:15557913 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889 		JBrowse link
G Plau plasminogen activator, urokinase ISO CTD Direct Evidence: therapeutic CTD PMID:1713745 PMID:9181759 PMID:9731615 PMID:15557913 NCBI chr15:3,644,296...3,650,765
Ensembl chr15:3,644,769...3,650,819 		JBrowse link
G Txn1 thioredoxin 1 ISO RGD PMID:15694802 RGD:1580783 NCBI chr 5:75,049,735...75,057,731
Ensembl chr 5:75,049,747...75,057,752 		JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A ISO CTD Direct Evidence: marker/mechanism CTD PMID:22196138 NCBI chr 5:143,111,342...143,120,131
Ensembl chr 5:143,111,074...143,120,165 		JBrowse link
acute myocardial infarction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 ISO RGD PMID:26476955 RGD:11552746 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167 		JBrowse link
G Cacng4 calcium voltage-gated channel auxiliary subunit gamma 4 ISO mRNA:decreased expression:blood: RGD PMID:27746059 RGD:13524557 NCBI chr10:95,954,160...96,015,484
Ensembl chr10:95,951,234...96,015,499 		JBrowse link
G Casp3 caspase 3 treatment IEP RGD PMID:26550220 RGD:13782284 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204 		JBrowse link
G Casp7 caspase 7 treatment IEP RGD PMID:26550220 RGD:13782284 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta treatment IEP RGD PMID:26591365 RGD:13792778 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268 		JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 IEP RGD PMID:24837094 RGD:40813741 NCBI chr 9:47,133,483...47,184,316
Ensembl chr 9:47,134,034...47,182,170 		JBrowse link
G Il33 interleukin 33 IEP RGD PMID:24837094 RGD:40813741 NCBI chr 1:248,112,611...248,147,030
Ensembl chr 1:248,132,090...248,147,029 		JBrowse link
G Mir146a microRNA 146a ISO miRNA:increased expression:peripheral blood mononuclear cell, plasma RGD PMID:31866771 RGD:21081515 NCBI chr10:28,962,476...28,962,570
Ensembl chr10:28,962,476...28,962,570 		JBrowse link
G Mir155 microRNA 155 ISO miRNA:decreased expression:peripheral blood mononuclear cell, plasma RGD PMID:31866771 RGD:21081515 NCBI chr11:24,176,603...24,176,667
Ensembl chr11:24,176,603...24,176,667 		JBrowse link
G Mir21 microRNA 21 ISO miRNA:increased expression:peripheral blood mononuclear cell, plasma RGD PMID:31866771 RGD:21081515 NCBI chr10:73,902,210...73,902,301
Ensembl chr10:73,902,210...73,902,301 		JBrowse link
G Mir223 microRNA 223 treatment IMP RGD PMID:29689569 RGD:25823140 NCBI chr  X:65,367,812...65,367,921
Ensembl chr  X:65,367,812...65,367,921 		JBrowse link
G Serping1 serpin family G member 1 ISO
IEP		 mRNA:increased expression:heart RGD PMID:26476955, PMID:26476955 RGD:11552746, RGD:11552746 NCBI chr 3:72,161,230...72,171,109
Ensembl chr 3:72,161,189...72,171,078 		JBrowse link
anterolateral myocardial infarction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edn1 endothelin 1 ISO protein:increased expression:aortic root, coronary sinus, plasma (human) RGD PMID:12581682 RGD:8661757 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324 		JBrowse link
G Serpine1 serpin family E member 1 disease_progression ISO protein:decreased expression, decreased activity:heart: RGD PMID:12615902, PMID:12615902 RGD:13208541, RGD:13208541 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482 		JBrowse link
aortic atherosclerosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E IMP RGD PMID:29459263 RGD:13703129 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057 		JBrowse link
G Capn1 calpain 1 IEP protein:increased activity:aorta RGD PMID:23006733 RGD:13792498 NCBI chr 1:221,346,081...221,370,965
Ensembl chr 1:221,346,066...221,370,322 		JBrowse link
G Mir223 microRNA 223 ISO RNA:increased expression:serum,aorta RGD PMID:26065992 RGD:25824846 NCBI chr  X:65,367,812...65,367,921
Ensembl chr  X:65,367,812...65,367,921 		JBrowse link
arteriolosclerosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 ISO associated with Renal Insufficiency, Chronic; protein:increased expression:serum: RGD PMID:22863782 RGD:7175516 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167 		JBrowse link
arteriosclerosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg5 ATP binding cassette subfamily G member 5 onset
susceptibility		 IAGP
ISO		 RGD PMID:16026620, PMID:11099417 RGD:1598659, RGD:1300331 NCBI chr 6:7,935,771...7,961,207
Ensembl chr 6:7,935,771...7,961,207 		JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 susceptibility ISO RGD PMID:11099417 RGD:1300331 NCBI chr 6:7,961,413...7,980,708
Ensembl chr 6:7,961,413...7,980,708 		JBrowse link
G Acat1 acetyl-CoA acetyltransferase 1 ISO mRNA:increased expression:atherosclerotic lesions (human) RGD PMID:15961705 RGD:1581042 NCBI chr 8:58,166,990...58,195,884
Ensembl chr 8:58,166,990...58,195,884 		JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 ISO RGD PMID:16675724 RGD:1601111 NCBI chr 1:47,972,399...47,992,654
Ensembl chr 1:47,972,399...47,992,653 		JBrowse link
G Aif1 allograft inflammatory factor 1 ISO RGD PMID:18204784 RGD:2313033 NCBI chr20:5,161,350...5,167,176
Ensembl chr20:5,161,333...5,166,448 		JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B ISO associated with Diabetes Mellitus, Experimental RGD PMID:16127462 RGD:1626081 NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956 		JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:erythrocyte RGD PMID:3949078 RGD:2300309 NCBI chr10:47,490,168...47,499,855
Ensembl chr10:47,490,153...47,499,876 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase ISO RGD
GAD		 PMID:14702425, PMID:15118671 RGD:734559, RGD:1331525 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303 		JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein ISO mRNA:increased expression:atherosclerotic lesions (human)
mRNA:increased expression:aorta, adipose tissue (mouse)		 RGD PMID:18258817, PMID:17379835 RGD:2313905, RGD:2313913 NCBI chr12:6,854,930...6,879,112
Ensembl chr12:6,854,920...6,879,154 		JBrowse link
G Alpl alkaline phosphatase, biomineralization associated ISO protein:decrease expression:serum RGD PMID:17010978 RGD:1601172 NCBI chr 5:156,086,496...156,141,513
Ensembl chr 5:156,086,497...156,141,537 		JBrowse link
G Apoa1 apolipoprotein A1 treatment ISO
IDA		 associated with Kidney Failure, Chronic GAD
RGD		 PMID:15118671, PMID:20639628 RGD:1331525, RGD:5508221 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875 		JBrowse link
G Apob apolipoprotein B ISO associated with Obesity RGD PMID:19260948 RGD:2312763 NCBI chr 6:33,176,826...33,216,381
Ensembl chr 6:33,176,778...33,224,997 		JBrowse link
G Apoe apolipoprotein E ISO CTD Direct Evidence: marker/mechanism CTD PMID:17118406 PMID:18287887 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057 		JBrowse link
G Apoh apolipoprotein H ISO protein:increased expression:serum RGD PMID:6613192 RGD:2313992 NCBI chr10:96,640,013...96,653,939
Ensembl chr10:96,639,924...96,653,938 		JBrowse link
G Atm ATM serine/threonine kinase susceptibility ISO RGD PMID:15863839 RGD:1601249 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045 		JBrowse link
G B2m beta-2 microglobulin ISO associated with Kidney Diseases RGD PMID:16221094 RGD:2311212 NCBI chr 3:114,087,287...114,093,311
Ensembl chr 3:114,087,287...114,093,309 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 ISO associated with Diabetes Mellitus, Experimental;mRNA:increased expression:aorta RGD PMID:18093596 RGD:2306988 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 ISO
IEP		 protein:increased secretion:serum (mouse)
protein:increased expression:plasma		 RGD PMID:19752857, PMID:16259780, PMID:14656931 RGD:4891452, RGD:2307165, RGD:4890030 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315 		JBrowse link
G Ccr5 C-C motif chemokine receptor 5 ISO RGD PMID:17138939 RGD:4890431 NCBI chr 8:133,192,398...133,215,599
Ensembl chr 8:133,197,032...133,215,614 		JBrowse link
G Cd36 CD36 molecule severity ISO protein:increased expression:plasma RGD PMID:18723424 RGD:2307207 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749 		JBrowse link
G Cdh13 cadherin 13 ISO protein:increased expression:aorta RGD PMID:11326751 RGD:2293555 NCBI chr19:50,848,793...51,971,618
Ensembl chr19:50,848,736...51,972,103 		JBrowse link
G Chi3l1 chitinase 3 like 1 ISO protein:increased expression:artery, plaque, macrophage (human) RGD PMID:10073974 RGD:4892604 NCBI chr13:51,022,844...51,030,797
Ensembl chr13:51,022,681...51,030,802 		JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 ISO RGD PMID:12600915 RGD:4891900 NCBI chr 8:128,740,756...128,754,514
Ensembl chr 8:128,740,756...128,754,514 		JBrowse link
G Dusp1 dual specificity phosphatase 1 ISO protein:increased expression:aorta RGD PMID:15242861 RGD:2298676 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418 		JBrowse link
G Egr1 early growth response 1 ISO mRNA, protein:increased expression:carotid artery, plaque (human)
protein:increased expression:atherosclerotic lesions, vascular associated smooth muscle cell, nucleus (mouse)		 RGD PMID:10712437, PMID:21099169, PMID:14670837 RGD:5131645, RGD:5131874, RGD:5131652 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429 		JBrowse link
G Esr1 estrogen receptor 1 ISO RGD PMID:17903303 RGD:4892301 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796 		JBrowse link
G F13a1 coagulation factor XIII A1 chain ISO RGD PMID:11941274 RGD:1581023 NCBI chr17:28,504,650...28,680,015
Ensembl chr17:28,504,623...28,680,362 		JBrowse link
G F7 coagulation factor VII severity ISO protein:increased activity:plasma (human) RGD PMID:9569183 RGD:2312403 NCBI chr16:81,824,610...81,834,923
Ensembl chr16:81,824,111...81,834,945 		JBrowse link
G Faslg Fas ligand ISO RGD PMID:14739407 RGD:1582424 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705 		JBrowse link
G Fbln5 fibulin 5 ISO RGD PMID:10428823 RGD:69830 NCBI chr 6:125,644,797...125,723,957
Ensembl chr 6:125,644,804...125,723,944 		JBrowse link
G Furin furin (paired basic amino acid cleaving enzyme) ISO RGD PMID:15756593 RGD:1582622 NCBI chr 1:142,185,092...142,198,167
Ensembl chr 1:142,185,094...142,197,182 		JBrowse link
G Gata2 GATA binding protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28569748 NCBI chr 4:120,129,028...120,142,490
Ensembl chr 4:120,133,713...120,142,488 		JBrowse link
G Gpx1 glutathione peroxidase 1 ISO associated with Diabetes Mellitus, Experimental RGD PMID:17420349 RGD:2306610 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522 		JBrowse link
G Gsta4 glutathione S-transferase alpha 4 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:15064094 PMID:20177342 NCBI chr 8:85,497,557...85,514,732
Ensembl chr 8:85,497,557...85,518,879 		JBrowse link
G Hgf hepatocyte growth factor severity ISO protein:increased expression:serum: RGD PMID:9350587 RGD:8548601 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362 		JBrowse link
G Hmox1 heme oxygenase 1 ISO RGD PMID:12958201 RGD:1598395 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456 		JBrowse link
G Hp haptoglobin susceptibility ISO associated with Hypertension;DNA:polymorphism RGD PMID:8228210, PMID:17068284 RGD:1626352, RGD:1626340 NCBI chr19:42,096,255...42,100,805
Ensembl chr19:42,097,995...42,100,804 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 ISO RGD PMID:17070529 RGD:1624204 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956 		JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28569748 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059 		JBrowse link
G Icos inducible T-cell co-stimulator ISO RGD PMID:17060381 RGD:1624268 NCBI chr 9:67,748,157...67,786,808
Ensembl chr 9:67,763,897...67,785,580 		JBrowse link
G Ifngr1 interferon gamma receptor 1 ISO RGD PMID:20655098 RGD:6480271 NCBI chr 1:15,062,380...15,080,815
Ensembl chr 1:15,062,432...15,080,907 		JBrowse link
G Igf1 insulin-like growth factor 1 ISO protein:increased expression:blood RGD PMID:15625284 RGD:2313768 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609 		JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 ISO protein:increased expression:blood RGD PMID:15625284 RGD:2313768 NCBI chr14:87,457,647...87,465,374
Ensembl chr14:87,457,647...87,465,374 		JBrowse link
G Il10 interleukin 10 susceptibility ISO RGD PMID:16523426, PMID:12765335 RGD:1598477, RGD:1598469 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392 		JBrowse link
G Il15 interleukin 15 ISO mRNA:increased expression:macrophage, aorta
mRNA:increased expression:carotid		 RGD PMID:11485899, PMID:11485899 RGD:1626612, RGD:1626612 NCBI chr19:23,542,606...23,624,366
Ensembl chr19:23,542,889...23,554,594 		JBrowse link
G Il18bp interleukin 18 binding protein ISO RGD PMID:11577031 RGD:4892618 NCBI chr 1:167,091,521...167,095,727
Ensembl chr 1:167,091,522...167,093,560 		JBrowse link
G Il1b interleukin 1 beta susceptibility ISO
IEP		 DNA:SNP:promoter
associated with Diabetes Mellitus, Type 2;protein:decreased expression:monocyte
associated with Chlamydia Infections		 RGD PMID:17213232, PMID:17189873, PMID:17132885 RGD:1626624, RGD:1626627, RGD:1626629 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726 		JBrowse link
G Il6st interleukin 6 cytokine family signal transducer susceptibility ISO DNA:SNPs RGD PMID:17664290, PMID:17664290 RGD:1626686, RGD:1626686 NCBI chr 2:44,279,199...44,319,427
Ensembl chr 2:44,289,393...44,314,944 		JBrowse link
G Itga1 integrin subunit alpha 1 ISO atherosclerosis; DNA:knockout::genetic knockout or treatment with a blocking antibody reduced atherosclerotic inflammation and plaque formation in ApoE-/- mice (mouse) RGD PMID:15976328 RGD:2302133 NCBI chr 2:47,127,403...47,281,387
Ensembl chr 2:47,127,219...47,281,421 		JBrowse link
G Itga2 integrin subunit alpha 2 susceptibility ISO RGD PMID:11978651 RGD:1582304 NCBI chr 2:46,996,904...47,097,011
Ensembl chr 2:47,000,323...47,096,961 		JBrowse link
G Itga7 integrin subunit alpha 7 IEP Atherogenesis RGD PMID:14988073 RGD:1600025 NCBI chr 7:3,355,079...3,383,886
Ensembl chr 7:3,355,116...3,384,675 		JBrowse link
G Itgb3 integrin subunit beta 3 ISO RGD PMID:12746502 RGD:5100478 NCBI chr10:92,667,869...92,783,413
Ensembl chr10:92,667,869...92,783,410 		JBrowse link
G Kdr kinase insert domain receptor IEP
ISO		 RGD PMID:15665766, PMID:16873710 RGD:1581706, RGD:1581713 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183 		JBrowse link
G Kl Klotho ISO CTD Direct Evidence: marker/mechanism CTD PMID:9363890, PMID:9363890 RGD:10403047 NCBI chr12:942,974...987,206
Ensembl chr12:943,006...987,551 		JBrowse link
G Lcat lecithin cholesterol acyltransferase susceptibility ISO RGD PMID:12673583, PMID:12673583 RGD:1581779, RGD:1581779 NCBI chr19:37,913,333...37,916,799
Ensembl chr19:37,913,336...37,916,813 		JBrowse link
G Ldlr low density lipoprotein receptor ISO RGD PMID:12969990 RGD:1581826 NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903 		JBrowse link
G Lepr leptin receptor ISO RGD PMID:11460888 RGD:1581846 NCBI chr 5:120,503,475...120,682,281
Ensembl chr 5:120,564,645...120,682,221 		JBrowse link
G Lipe lipase E, hormone sensitive type IDA
ISO		 RGD PMID:10064727, PMID:10729384 RGD:1581868, RGD:1581867 NCBI chr 1:82,248,031...82,266,727
Ensembl chr 1:82,248,046...82,266,727 		JBrowse link
G Lipg lipase G, endothelial type ISO RGD PMID:15304490 RGD:1581874 NCBI chr18:70,903,528...70,924,434
Ensembl chr18:70,901,710...70,924,708 		JBrowse link
G Lmna lamin A/C IEP protein:increased expression:aorta RGD PMID:16620292 RGD:2302364 NCBI chr 2:187,842,884...187,863,552
Ensembl chr 2:187,842,885...187,863,516 		JBrowse link
G Lox lysyl oxidase IDA RGD PMID:24127 RGD:1581899 NCBI chr18:47,500,320...47,577,819
Ensembl chr18:47,500,330...47,577,819 		JBrowse link
G Lrp1 LDL receptor related protein 1 susceptibility ISO associated with Hypercholesterolemia RGD PMID:17303763, PMID:14739216 RGD:1625012, RGD:1581910 NCBI chr 7:70,846,313...70,927,028
Ensembl chr 7:70,846,344...70,926,903 		JBrowse link
G Lta lymphotoxin alpha ISO RGD PMID:11809756 RGD:1581936 NCBI chr20:4,851,889...4,854,677
Ensembl chr20:4,852,496...4,854,677 		JBrowse link
G Ltb4r leukotriene B4 receptor ISO RGD PMID:16043658 RGD:1581956 NCBI chr15:34,449,299...34,453,352
Ensembl chr15:34,452,116...34,453,171 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 ISO RGD PMID:15567863 RGD:1582314 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase ISO protein:increased expression:femoral artery, atherosclerotic lesions (human) RGD PMID:17405187 RGD:2317493 NCBI chr 4:44,747,467...44,854,628
Ensembl chr 4:44,774,741...44,852,665 		JBrowse link
G Mgp matrix Gla protein ISO RGD PMID:8200973 RGD:1582504 NCBI chr 4:170,856,783...170,860,105
Ensembl chr 4:170,856,751...170,860,225 		JBrowse link
G Mif macrophage migration inhibitory factor ISO RGD PMID:17435771 RGD:1641949 NCBI chr20:13,715,219...13,732,980
Ensembl chr20:13,732,198...13,732,859 		JBrowse link
G Mmp1 matrix metallopeptidase 1 ISO RGD PMID:15621056 RGD:1582525 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591 		JBrowse link
G Mmp12 matrix metallopeptidase 12 ISO RGD PMID:16221765 RGD:1582354 NCBI chr 8:5,594,717...5,616,494
Ensembl chr 8:5,606,592...5,616,493 		JBrowse link
G Mmp13 matrix metallopeptidase 13 susceptibility ISO RGD PMID:12392760, PMID:16230484 RGD:1582549, RGD:1582544 NCBI chr 8:5,522,739...5,533,018
Ensembl chr 8:5,522,739...5,533,018 		JBrowse link
G Mmp14 matrix metallopeptidase 14 IEP RGD PMID:12526080 RGD:1582580 NCBI chr15:33,074,441...33,083,666
Ensembl chr15:33,074,441...33,083,655 		JBrowse link
G Mmp2 matrix metallopeptidase 2 ISO RGD PMID:12526080 RGD:1582580 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611 		JBrowse link
G Mmp3 matrix metallopeptidase 3 ISO RGD PMID:15823277 RGD:1580550 NCBI chr 8:5,676,608...5,698,579
Ensembl chr 8:5,676,665...5,698,579 		JBrowse link
G Mmp9 matrix metallopeptidase 9 IDA
ISO		 RGD PMID:16317521, PMID:15823277 RGD:1582628, RGD:1580550 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520 		JBrowse link
G Msr1 macrophage scavenger receptor 1 ISO RGD PMID:14664792, PMID:15567863, PMID:9069289 RGD:2306130, RGD:1582314, RGD:1582669 NCBI chr16:56,817,714...56,900,025
Ensembl chr16:56,813,791...56,900,052 		JBrowse link
G Ndufs6 NADH:ubiquinone oxidoreductase subunit S6 IEP protein:increased expression:aorta RGD PMID:16620292 RGD:2302364 NCBI chr 2:26,471,173...26,471,587
Ensembl chr 2:26,471,173...26,471,584 		JBrowse link
G Nfkbia NFKB inhibitor alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:28569748 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457 		JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 ISO protein:decreased expression:artery RGD PMID:17272673 RGD:2299058 NCBI chr10:81,648,216...81,653,717
Ensembl chr10:81,648,216...81,653,717 		JBrowse link
G Nos1 nitric oxide synthase 1 ISO RGD PMID:16627802 RGD:1642131 NCBI chr12:44,214,949...44,405,530
Ensembl chr12:44,213,943...44,520,341 		JBrowse link
G Nos3 nitric oxide synthase 3 ISO CTD Direct Evidence: therapeutic CTD PMID:14736551 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410 		JBrowse link
G Notch4 notch receptor 4 ISO RGD PMID:18802018 RGD:6480862 NCBI chr20:4,329,794...4,353,868
Ensembl chr20:4,329,811...4,353,785 		JBrowse link
G Npc1l1 NPC1 like intracellular cholesterol transporter 1 ISO RGD PMID:17218600 RGD:1642183 NCBI chr14:86,345,946...86,560,694
Ensembl chr14:86,345,953...86,560,694 		JBrowse link
G Nppc natriuretic peptide C ISO RGD PMID:8989116 RGD:1642296 NCBI chr 9:93,731,436...93,735,636
Ensembl chr 9:93,731,436...93,735,636 		JBrowse link
G Npy neuropeptide Y ISO DNA:missense mutation:cds:p.L7P (human) RGD PMID:11689216 RGD:1580177 NCBI chr 4:79,557,856...79,565,059
Ensembl chr 4:79,557,854...79,565,097 		JBrowse link
G P2ry12 purinergic receptor P2Y12 ISO RGD PMID:19295309 RGD:6480535 NCBI chr 2:149,440,807...149,482,592
Ensembl chr 2:149,441,598...149,444,548 		JBrowse link
G Pappa1 pappalysin 1 ISO protein:increased expression:serum
mRNA:increased expression:aorta		 RGD PMID:16614002, PMID:17510462 RGD:1642326, RGD:1642325 NCBI chr 5:80,919,932...81,153,904
Ensembl chr 5:80,920,568...81,150,940 		JBrowse link
G Pla2g15 phospholipase A2, group XV ISO RGD PMID:15781238 RGD:1582126 NCBI chr19:38,129,666...38,146,958
Ensembl chr19:38,129,584...38,146,956 		JBrowse link
G Pon1 paraoxonase 1 ISO associated with Metabolic Syndrome X RGD PMID:16627808 RGD:2313273 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma treatment IDA RGD PMID:15967870 RGD:8553041 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380 		JBrowse link
G Prdx6 peroxiredoxin 6 ISO RGD PMID:15488866 RGD:1580711 NCBI chr13:79,077,567...79,088,113
Ensembl chr13:79,077,033...79,088,127 		JBrowse link
G Ptgds prostaglandin D2 synthase susceptibility ISO RGD PMID:15970590 RGD:1642581 NCBI chr 3:2,686,125...2,689,059
Ensembl chr 3:2,686,123...2,689,084 		JBrowse link
G Ptger4 prostaglandin E receptor 4 ISO RGD PMID:16020747 RGD:1581284 NCBI chr 2:54,951,625...54,966,470
Ensembl chr 2:54,952,821...54,963,448 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 severity
resistance		 ISO RGD PMID:17643885, PMID:17643885, PMID:16458279 RGD:1642592, RGD:1642592, RGD:1581287 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit IEP protein:increased expression:aorta RGD PMID:18637019 RGD:2298774 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249 		JBrowse link
G Senp1 SUMO specific peptidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28569748 NCBI chr 7:139,626,444...139,684,587
Ensembl chr 7:139,630,515...139,675,245 		JBrowse link
G Serpina1 serpin family A member 1 disease_progression ISO DNA, protein:polymorphism, decreased expression: :p.A213V, 11478A>G, p.E264V, p.E342K (human)
CTD Direct Evidence: marker/mechanism		 CTD PMID:12692006, PMID:12692006 RGD:1643145 NCBI chr 6:127,610,241...127,632,265
Ensembl chr 6:127,610,243...127,632,265 		JBrowse link
G Soat2 sterol O-acyltransferase 2 susceptibility ISO RGD PMID:17431188 RGD:1625282 NCBI chr 7:143,754,892...143,767,989
Ensembl chr 7:143,754,892...143,767,989 		JBrowse link
G Tbxa2r thromboxane A2 receptor TAS RGD PMID:11777901 RGD:619549 NCBI chr 7:11,253,153...11,259,233
Ensembl chr 7:11,253,180...11,257,977 		JBrowse link
G Tbxas1 thromboxane A synthase 1 IDA RGD PMID:11331452 RGD:1601459 NCBI chr 4:66,624,181...66,846,745
Ensembl chr 4:66,670,618...66,846,805 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO protein:increased expression:aorta RGD PMID:16733295 RGD:1580959 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 ISO protein:increased expression:aorta RGD PMID:16733295 RGD:1580959 NCBI chr 8:124,310,288...124,399,345
Ensembl chr 8:124,312,754...124,399,494 		JBrowse link
G Tlr4 toll-like receptor 4 susceptibility ISO DNA:SNP: :c.896A>G (human) RGD PMID:16890863 RGD:1624159 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052 		JBrowse link
G Tnfrsf14 TNF receptor superfamily member 14 ISO protein:increased expression:carotid artery, atherosclerotic lesions (human) RGD PMID:11742877 RGD:2317295 NCBI chr 5:172,328,259...172,337,221
Ensembl chr 5:172,328,262...172,335,892 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A susceptibility ISO RGD PMID:17442899 RGD:1624181 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633 		JBrowse link
G Tnfsf10 TNF superfamily member 10 ISO associated with Diabetes Mellitus, Experimental RGD PMID:17000905 RGD:2312742 NCBI chr 2:113,008,008...113,026,899
Ensembl chr 2:113,007,549...113,026,899 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28569748 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619 		JBrowse link
G Vcan versican TAS RGD PMID:10397680 RGD:632588 NCBI chr 2:18,490,102...18,587,340
Ensembl chr 2:18,490,102...18,565,842 		JBrowse link
G Vldlr very low density lipoprotein receptor ISO RGD PMID:10985956 RGD:1625570 NCBI chr 1:245,236,819...245,273,688
Ensembl chr 1:245,237,736...245,269,205 		JBrowse link
arteriosclerosis obliterans term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Thpo thrombopoietin ISO RGD PMID:10822072 RGD:1601656 NCBI chr11:82,845,676...82,853,439
Ensembl chr11:83,868,655...83,873,910
Ensembl chr11:83,868,655...83,873,910 		JBrowse link
atherosclerosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22022523 NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015 		JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11138003 NCBI chr 6:7,935,771...7,961,207
Ensembl chr 6:7,935,771...7,961,207 		JBrowse link
G Add1 adducin 1 ISO DNA:missense mutation:cds:p.G460W (human) RGD PMID:17082469 RGD:5147995 NCBI chr14:81,367,466...81,426,610
Ensembl chr14:81,367,468...81,426,496 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing treatment ISO CTD Direct Evidence: therapeutic CTD PMID:18931039, PMID:12451000 RGD:8694473 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488 		JBrowse link
G Ager advanced glycosylation end product-specific receptor treatment ISO
IEP		 CTD Direct Evidence: marker/mechanism
associated with Kidney Failure, Chronic; protein:decreased expression:plasma (human)		 CTD PMID:19939336 PMID:20372816, PMID:22552116, PMID:23936343, PMID:22038096, PMID:21906738, PMID:20835270, PMID:21418204 RGD:6784514, RGD:8695994, RGD:7245947, RGD:6767557, RGD:6784516, RGD:6784515 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079 		JBrowse link
G Agt angiotensinogen treatment IMP
ISO		 associated with Hypertension
CTD Direct Evidence: marker/mechanism		 CTD PMID:21925196 PMID:22539767, PMID:22977667 RGD:8549467 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433 		JBrowse link
G Ahr aryl hydrocarbon receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:22228805 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 severity ISO RGD PMID:18054314 RGD:5509083 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258 		JBrowse link
G Alox15 arachidonate 15-lipoxygenase ISO CTD Direct Evidence: therapeutic CTD PMID:16303615, PMID:18206890 RGD:5509610 NCBI chr10:56,953,692...56,962,145
Ensembl chr10:56,953,691...56,962,161 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16698924 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303 		JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:16698924 NCBI chr12:6,854,930...6,879,112
Ensembl chr12:6,854,920...6,879,154 		JBrowse link
G Apoa1 apolipoprotein A1 treatment ISO RGD PMID:18287885, PMID:23078847 RGD:7241575, RGD:7241852 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875 		JBrowse link
G Apoa4 apolipoprotein A4 ISO CTD Direct Evidence: therapeutic CTD PMID:15822908 NCBI chr 8:50,536,983...50,539,371
Ensembl chr 8:50,537,009...50,539,376 		JBrowse link
G Apoe apolipoprotein E treatment ISO CTD Direct Evidence: marker/mechanism CTD PMID:9169506 PMID:9409251 PMID:9649566 PMID:11095717 PMID:11231916 PMID:11947894 PMID:12871831 PMID:14594625 PMID:16020748 PMID:16303615 PMID:17438151 PMID:18093987 PMID:18269830 PMID:19124646 PMID:19682479 PMID:20093625 PMID:21043830 PMID:21512104 PMID:21908651 PMID:22005275 PMID:22022523 PMID:22228805 PMID:23148895 PMID:23639522 PMID:24017971 PMID:24096154 PMID:24330719 PMID:25020133 PMID:28483571 PMID:30376133, PMID:1411543, PMID:7593602 RGD:734968, RGD:7771549 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057 		JBrowse link
G Bcl3 BCL3, transcription coactivator ISO CTD Direct Evidence: marker/mechanism CTD PMID:25374339 NCBI chr 1:80,730,758...80,745,273
Ensembl chr 1:80,730,499...80,744,831 		JBrowse link
G Casp3 caspase 3 treatment IEP associated with type 2 diabetes mellitus RGD PMID:29213335 RGD:13792600 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204 		JBrowse link
G Casr calcium-sensing receptor ISO
IEP		 protein:decreased expression:tibial artery (human)
protein:increased expression:myocardium (rat)		 RGD PMID:18852253, PMID:22527939 RGD:7205454, RGD:7205672 NCBI chr11:67,188,204...67,262,261
Ensembl chr11:67,188,630...67,258,771 		JBrowse link
G Cav1 caveolin 1 treatment IEP RGD PMID:23675421 RGD:8662275 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 treatment
severity		 ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:aorta (mouse)		 CTD PMID:12677255 PMID:12928151 PMID:20720404, PMID:11486244, PMID:15823270 RGD:8548896, RGD:7401235 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24370436 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24370436 NCBI chr10:70,870,926...70,886,357
Ensembl chr10:70,884,531...70,886,355 		JBrowse link
G Ccr5 C-C motif chemokine receptor 5 treatment ISO RGD PMID:16763157 RGD:8549763 NCBI chr 8:133,192,398...133,215,599
Ensembl chr 8:133,197,032...133,215,614 		JBrowse link
G Ccr6 C-C motif chemokine receptor 6 ISO RGD PMID:24114205 RGD:7483610 NCBI chr 1:53,063,380...53,087,519
Ensembl chr 1:53,065,025...53,087,474 		JBrowse link
G Cd36 CD36 molecule treatment ISO
IEP		 RGD PMID:19264766, PMID:26003171, PMID:20037584 RGD:6893502, RGD:11041151, RGD:6893559 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749 		JBrowse link
G Cd40 CD40 molecule treatment ISO
IDA
IEP		 associated with Gram-Negative Bacterial Infections;protein:increased expression:aorta
associated with Hypercholesterolemia		 RGD PMID:20505314, PMID:23984971, PMID:23984971, PMID:16317521 RGD:5490534, RGD:8547801, RGD:8547801, RGD:1582628 NCBI chr 3:161,519,789...161,534,943
Ensembl chr 3:161,519,743...161,534,704 		JBrowse link
G Cd40lg CD40 ligand treatment ISO
IDA
IEP		 associated with Hypercholesterolemia
protein:increased expression:plasma		 RGD PMID:20705757, PMID:26261622, PMID:23984971, PMID:16317521, PMID:21817131 RGD:5490529, RGD:11344965, RGD:8547801, RGD:1582628, RGD:7248421 NCBI chr  X:159,703,703...159,714,886
Ensembl chr  X:159,703,578...159,716,562 		JBrowse link
G Cela2a chymotrypsin like elastase 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:31358993 NCBI chr 5:160,374,031...160,383,782
Ensembl chr 5:160,374,031...160,383,782 		JBrowse link
G Clu clusterin treatment IDA RGD PMID:15961700 RGD:9068390 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857 		JBrowse link
G Cnr2 cannabinoid receptor 2 ISO CTD Direct Evidence: therapeutic CTD PMID:15815632 NCBI chr 5:154,242,010...154,268,126
Ensembl chr 5:154,260,062...154,268,126 		JBrowse link
G Col4a2 collagen type IV alpha 2 chain susceptibility ISO DNA:SNP: :rs72657934(human) RGD PMID:28642624 RGD:13450936 NCBI chr16:83,386,388...83,522,169
Ensembl chr16:83,387,364...83,438,561 		JBrowse link
G Crp C-reactive protein disease_progression ISO protein:increased expression:serum:
CTD Direct Evidence: marker/mechanism		 CTD PMID:16931792, PMID:18535598 RGD:9491769 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713 		JBrowse link
G Csf1 colony stimulating factor 1 ISO protein:increased expression:plasma (mouse)
associated with Kidney Failure, Chronic		 RGD PMID:9637704, PMID:16166801 RGD:734837, RGD:7257575 NCBI chr 2:210,522,370...210,550,546
Ensembl chr 2:210,522,375...210,550,560 		JBrowse link
G Ctsb cathepsin B ISO RGD PMID:12213722 RGD:5687152 NCBI chr15:46,316,741...46,337,613
Ensembl chr15:46,316,741...46,337,612 		JBrowse link
G Ctsd cathepsin D ISO RGD PMID:12213722 RGD:5687152 NCBI chr 1:215,541,570...215,553,446
Ensembl chr 1:215,541,542...215,553,451 		JBrowse link
G Ctsl cathepsin L ISO RGD PMID:12213722 RGD:5687152 NCBI chr17:1,873,105...1,879,266
Ensembl chr17:1,872,848...1,879,279 		JBrowse link
G Ctss cathepsin S ISO RGD PMID:12213722 RGD:5687152 NCBI chr 2:197,655,780...197,679,768
Ensembl chr 2:197,655,786...197,679,458 		JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 ISO RGD PMID:23887641 RGD:9479739 NCBI chr 8:128,740,756...128,754,514
Ensembl chr 8:128,740,756...128,754,514 		JBrowse link
G Cyba cytochrome b-245 alpha chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:20720404 NCBI chr19:55,249,634...55,257,824
Ensembl chr19:55,249,616...55,257,876 		JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11166758 PMID:19801147 NCBI chr 9:81,968,285...81,998,213
Ensembl chr 9:81,968,332...81,998,169 		JBrowse link
G Edn1 endothelin 1 treatment ISO RGD PMID:16806235 RGD:8661682 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324 		JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 treatment ISO RGD PMID:26848160 RGD:11251766 NCBI chr19:57,660,194...57,701,158
Ensembl chr19:57,662,278...57,699,113 		JBrowse link
G Ephx2 epoxide hydrolase 2 ISO RGD PMID:20224052 RGD:5688357 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279 		JBrowse link
G Esr1 estrogen receptor 1 treatment ISO CTD Direct Evidence: marker/mechanism CTD PMID:11894143, PMID:11160157 RGD:8553067 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796 		JBrowse link
G Esr2 estrogen receptor 2 ISO RGD PMID:21697723 RGD:5508792 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251 		JBrowse link
G F11r F11 receptor ISO mRNA:increased expression:carotid artery RGD PMID:15681301 RGD:7488921 NCBI chr13:89,826,272...89,850,151
Ensembl chr13:89,826,254...89,850,612 		JBrowse link
G F2 coagulation factor II treatment IDA RGD PMID:20979870 RGD:7387315 NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031 		JBrowse link
G Fas Fas cell surface death receptor treatment IEP associated with type 2 diabetes mellitus RGD PMID:29213335 RGD:13792600 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790 		JBrowse link
G Faslg Fas ligand ISO CTD Direct Evidence: marker/mechanism CTD PMID:15063428 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705 		JBrowse link
G Fcgr2a Fc fragment of IgG receptor IIa onset ISO DNA:polymorphism: :p.H131R (human) RGD PMID:19490059 RGD:5147923 NCBI chr13:91,146,878...91,163,691
Ensembl chr13:91,168,973...91,198,036
Ensembl chr13:91,168,973...91,198,036 		JBrowse link
G Fcgr2b Fc fragment of IgG receptor IIb ISO RGD PMID:17053192 RGD:7240526 NCBI chr13:89,329,298...89,343,916
Ensembl chr13:89,327,794...89,433,815 		JBrowse link
G Fgf21 fibroblast growth factor 21 ISO associated with Diabetes Mellitus, Type 2;protein:increased expression:serum: RGD PMID:26047614 RGD:10401919 NCBI chr 1:101,595,579...101,596,822
Ensembl chr 1:101,595,579...101,596,822 		JBrowse link
G Grn granulin precursor ISO protein:increased expression:smooth muscle cell, macrophage RGD PMID:19321167 RGD:5509781 NCBI chr10:90,377,103...90,383,207
Ensembl chr10:90,376,933...90,383,205 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19822795 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306 		JBrowse link
G Hmgb1 high mobility group box 1 treatment IEP RGD PMID:20519084 RGD:10402182 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237 		JBrowse link
G Hnrnpc heterogeneous nuclear ribonucleoprotein C ISO protein:increased expression:internal carotid artery, smooth muscle cell (human) RGD PMID:18508286 RGD:10054381 NCBI chr15:28,486,605...28,517,353
Ensembl chr15:28,486,617...28,517,353 		JBrowse link
G Hp haptoglobin treatment IEP
ISO		 CTD Direct Evidence: marker/mechanism CTD PMID:16597321, PMID:23665315 RGD:11041860 NCBI chr19:42,096,255...42,100,805
Ensembl chr19:42,097,995...42,100,804 		JBrowse link
G Hrh1 histamine receptor H 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25020133 NCBI chr 4:146,374,596...146,458,148
Ensembl chr 4:146,455,332...146,457,074 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A ISO DNA:SNP:promoter:-110A>C(rs1008438) (human) RGD PMID:20490736, PMID:22328194 RGD:5147595, RGD:7257649 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:16513158 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815 		JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12677255 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059 		JBrowse link
G Ifng interferon gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:9169506 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419 		JBrowse link
G Igf2 insulin-like growth factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11726660 NCBI chr 1:215,828,102...215,839,081
Ensembl chr 1:215,828,102...215,846,911 		JBrowse link
G Il17a interleukin 17A treatment ISO RGD PMID:21300351 RGD:9170237 NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786 		JBrowse link
G Il18 interleukin 18 treatment IEP
ISO		 RGD PMID:23685195, PMID:16732281 RGD:8655997, RGD:14695532 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299 		JBrowse link
G Il1b interleukin 1 beta ISO associated with Renal Insufficiency, Chronic RGD PMID:21245127 RGD:7175328 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726 		JBrowse link
G Il2 interleukin 2 ISO associated with Diabetes Mellitus, Type 1 RGD PMID:21606463 RGD:5147904 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854 		JBrowse link
G Il6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19330073 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807 		JBrowse link
G Kdr kinase insert domain receptor treatment ISO RGD PMID:17303776 RGD:8551768 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183 		JBrowse link
G Kl Klotho ISO RGD PMID:11027545 RGD:10403056 NCBI chr12:942,974...987,206
Ensembl chr12:943,006...987,551 		JBrowse link
G Ldlr low density lipoprotein receptor ISO
IMP		 CTD Direct Evidence: marker/mechanism|therapeutic
DNA:mutation:exon:478T > A(rat)		 CTD PMID:11947894 PMID:18450471 PMID:22153697 PMID:25619500 PMID:28899902, PMID:9614153, PMID:22293196 RGD:5490255, RGD:12910105 NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903 		JBrowse link
G Lta4h leukotriene A4 hydrolase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16698924 NCBI chr 7:34,288,333...34,320,243
Ensembl chr 7:34,288,365...34,320,235 		JBrowse link
G Mir146a microRNA 146a severity ISO miRNA:increased expression:peripheral blood mononuclear cell, plasma RGD PMID:31866771 RGD:21081515 NCBI chr10:28,962,476...28,962,570
Ensembl chr10:28,962,476...28,962,570 		JBrowse link
G Mir155 microRNA 155 treatment
severity		 ISO associated with Bacteremia
miRNA:decreased expression:peripheral blood mononuclear cell, plasma		 RGD PMID:28970282, PMID:28646427, PMID:31866771, PMID:27856635 RGD:21079445, RGD:24922209, RGD:21081515, RGD:21079446 NCBI chr11:24,176,603...24,176,667
Ensembl chr11:24,176,603...24,176,667 		JBrowse link
G Mir21 microRNA 21 severity ISO miRNA:increased expression:peripheral blood mononuclear cell, plasma RGD PMID:31866771 RGD:21081515 NCBI chr10:73,902,210...73,902,301
Ensembl chr10:73,902,210...73,902,301 		JBrowse link
G Mir223 microRNA 223 ISO RNA:increased expression:serum,artery RGD PMID:26065992 RGD:25824846 NCBI chr  X:65,367,812...65,367,921
Ensembl chr  X:65,367,812...65,367,921 		JBrowse link
G Mmp1 matrix metallopeptidase 1 susceptibility ISO human gene in mouse model
CTD Direct Evidence: marker/mechanism		 CTD PMID:21742783, PMID:11375412 RGD:7207025 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591 		JBrowse link
G Mmp2 matrix metallopeptidase 2 treatment IEP
ISO		 RGD PMID:16317521, PMID:20370796 RGD:1582628, RGD:8657031 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase severity ISO associated with Kidney Failure, Chronic; DNA:transversion:cds:g.1298A>C (human) RGD PMID:17899317 RGD:6893579 NCBI chr 5:164,844,642...164,864,360
Ensembl chr 5:164,845,925...164,860,910 		JBrowse link
G Nectin2 nectin cell adhesion molecule 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28062492 NCBI chr 1:80,631,449...80,666,617
Ensembl chr 1:80,631,450...80,666,585 		JBrowse link
G Ngf nerve growth factor ISO protein:decreased expression:coronary artery (human) RGD PMID:11689207 RGD:5508382 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453 		JBrowse link
G Ngfr nerve growth factor receptor ISO protein:increased expression:adventitia, vasa vasorum (human) RGD PMID:11689207 RGD:5508382 NCBI chr10:83,389,828...83,408,061
Ensembl chr10:83,389,847...83,408,061 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 ISO RGD PMID:24324141 RGD:8158039 NCBI chr19:19,342,061...19,389,366
Ensembl chr19:19,332,594...19,377,492 		JBrowse link
G Nos2 nitric oxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20720404 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190 		JBrowse link
G Nos3 nitric oxide synthase 3 susceptibility ISO DNA:snp:exon:c.894G>T (human)
CTD Direct Evidence: marker/mechanism|therapeutic		 CTD PMID:12677255 PMID:20720404, PMID:21114134, PMID:12163452 RGD:7771564, RGD:7771607 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410 		JBrowse link
G Npc1 NPC intracellular cholesterol transporter 1 ISO CTD Direct Evidence: therapeutic CTD PMID:18483620 NCBI chr18:3,616,878...3,662,656
Ensembl chr18:3,616,878...3,662,683 		JBrowse link
G Nppb natriuretic peptide B susceptibility ISO associated with Renal Insufficiency, chronic;protein:increased expression:blood:
associated with Hypertension,Renal; DNA:SNP:promoter: -381 T>C,rs198389 (human)		 RGD PMID:22863432, PMID:19413180 RGD:7247628, RGD:7248594 NCBI chr 5:164,796,176...164,797,538
Ensembl chr 5:164,796,185...164,797,531 		JBrowse link
G Npy neuropeptide Y severity ISO RGD PMID:21468772 RGD:10448273 NCBI chr 4:79,557,856...79,565,059
Ensembl chr 4:79,557,854...79,565,097 		JBrowse link
G Npy1r neuropeptide Y receptor Y1 ISO RGD PMID:21468772 RGD:10448273 NCBI chr16:24,779,480...24,789,131
Ensembl chr16:24,779,477...24,788,740 		JBrowse link
G Npy2r neuropeptide Y receptor Y2 ISO RGD PMID:21468772 RGD:10448273 NCBI chr 2:181,528,949...181,538,145
Ensembl chr 2:181,530,832...181,531,978 		JBrowse link
G Npy5r neuropeptide Y receptor Y5 ISO RGD PMID:21468772 RGD:10448273 NCBI chr16:24,796,685...24,805,730
Ensembl chr16:24,797,124...24,805,079 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 ISO CTD Direct Evidence: therapeutic CTD PMID:30996006 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18093987 PMID:19124646, PMID:18093987 RGD:5683916 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716 		JBrowse link
G Pdgfrb platelet derived growth factor receptor beta treatment ISO RGD PMID:11413086 RGD:10449506 NCBI chr18:56,364,586...56,406,381
Ensembl chr18:56,364,620...56,406,381 		JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 severity
resistance		 ISO protein:increased expression:carotid artery (human) RGD PMID:22053073, PMID:21960570, PMID:17659202 RGD:6771176, RGD:6771359, RGD:6771223 NCBI chr10:94,850,971...94,913,202 JBrowse link
G Pgf placental growth factor ISO RGD PMID:19952000 RGD:6483589 NCBI chr 6:108,994,016...109,004,598
Ensembl chr 6:108,994,018...109,004,598 		JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma severity ISO RGD PMID:17483449 RGD:1642394 NCBI chr 6:51,465,696...51,501,234
Ensembl chr 6:51,465,908...51,498,337 		JBrowse link
G Pla2g2a phospholipase A2 group IIA ISO CTD Direct Evidence: marker/mechanism CTD PMID:19237014 NCBI chr 5:157,282,650...157,285,295
Ensembl chr 5:157,282,669...157,285,328 		JBrowse link
G Pla2g7 phospholipase A2 group VII ISO associated with Diabetes Mellitus, type 2;DNA:missense mutation: :994G>T(human) RGD PMID:21970837, PMID:12590019 RGD:6482784, RGD:7248796 NCBI chr 9:19,935,754...19,978,013
Ensembl chr 9:19,935,768...19,978,013 		JBrowse link
G Plat plasminogen activator, tissue type ISO CTD Direct Evidence: therapeutic CTD PMID:12677255 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889 		JBrowse link
G Plau plasminogen activator, urokinase ISO associated with Kidney Failure, Chronic; protein:increased expression:plasma (human) RGD PMID:17706748, PMID:15096455 RGD:7241201, RGD:7241203 NCBI chr15:3,644,296...3,650,765
Ensembl chr15:3,644,769...3,650,819 		JBrowse link
G Pltp phospholipid transfer protein ISO protein:increased expression:coronary artery (human) RGD PMID:12835223 RGD:1581039 NCBI chr 3:161,304,469...161,322,289
Ensembl chr 3:161,304,469...161,322,289 		JBrowse link
G Pon1 paraoxonase 1 susceptibility
treatment		 ISO mRNA:altered expression::human transgene expression in ApoE-KO mice was protective
CTD Direct Evidence: marker/mechanism|therapeutic
associated with Beta-Thalassemia;protein:decreased activity:serum (human)		 CTD PMID:16216721 PMID:16229851 PMID:16331452 PMID:19371607 PMID:21629682 PMID:26241956, PMID:20182519, PMID:21427447, PMID:20660283, PMID:16043712 RGD:5509927, RGD:11552582, RGD:8547574, RGD:8547562 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372 		JBrowse link
G Pon3 paraoxonase 3 ISO mRNA:altered expression::human transgene expression in ApoE-KO mice was protective RGD PMID:20182519 RGD:5509927 NCBI chr 4:30,311,981...30,338,679
Ensembl chr 4:30,311,982...30,338,679 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma ISO protein:increased expression:aortic sinus, endothelium (mouse)
CTD Direct Evidence: therapeutic		 CTD PMID:18269830, PMID:15779851 RGD:8552894 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380 		JBrowse link
G Ptges3 prostaglandin E synthase 3 ISO protein:decreased expression:mammary arteries (human) RGD PMID:14736553 RGD:5688075 NCBI chr 7:2,479,267...2,497,024
Ensembl chr 7:2,479,311...2,497,013 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20720404 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335 		JBrowse link
G Sell selectin L ISO RGD PMID:21760899 RGD:5685675 NCBI chr13:82,369,820...82,387,774
Ensembl chr13:82,369,493...82,387,631 		JBrowse link
G Selp selectin P ISO
IEP		 protein:increased expression:aorta RGD PMID:19834105, PMID:22340239 RGD:6478699, RGD:6480102 NCBI chr13:82,428,914...82,464,629
Ensembl chr13:82,429,063...82,464,628 		JBrowse link
G Serpine1 serpin family E member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12677255 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482 		JBrowse link
G Sirt1 sirtuin 1 IEP
ISO		 associated with Diabetes Mellitus, Type 2;mRNA:decreased expression:abdominal aorta
CTD Direct Evidence: marker/mechanism		 CTD PMID:20068143, PMID:21810449 RGD:9585743 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199 		JBrowse link
G Socs3 suppressor of cytokine signaling 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19330073 NCBI chr10:106,973,863...106,976,969
Ensembl chr10:106,975,178...106,976,040 		JBrowse link
G Sod1 superoxide dismutase 1 severity ISO mRNA:decreased expression:thoracic aorta (mouse)
CTD Direct Evidence: marker/mechanism		 CTD PMID:20720404, PMID:20347443 RGD:8655856 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862 		JBrowse link
G Sod2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:12677255 PMID:20720404 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19330073 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233 		JBrowse link
G Tlr2 toll-like receptor 2 ISO RGD PMID:17466307 RGD:8552973 NCBI chr 2:182,840,171...182,846,061
Ensembl chr 2:182,840,727...182,846,061 		JBrowse link
G Tlr4 toll-like receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12124407 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052 		JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:20720404, PMID:15823270 RGD:7401235 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
G Trim28 tripartite motif-containing 28 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31351049 NCBI chr 1:65,544,369...65,551,043
Ensembl chr 1:65,544,373...65,551,043 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21908651 NCBI chr10:59,799,123...59,824,208
Ensembl chr10:59,799,123...59,824,679 		JBrowse link
G Ttpa alpha tocopherol transfer protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:11095717 NCBI chr 5:34,007,926...34,029,315
Ensembl chr 5:34,007,920...34,028,452 		JBrowse link
G Ucn2 urocortin 2 ISO protein:increased expression:coronary artery, endothelium (human) RGD PMID:16026900 RGD:5508308 NCBI chr 8:117,727,216...117,728,765
Ensembl chr 8:117,727,877...117,728,764 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12677255 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619 		JBrowse link
G Vdr vitamin D receptor ISO RGD PMID:25801026 RGD:14402022 NCBI chr 7:139,344,452...139,394,138
Ensembl chr 7:139,342,063...139,394,166 		JBrowse link
G Vegfa vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Atherosclerosis, susceptibility to		 CTD
ClinVar		 PMID:15732116 PMID:15937083 PMID:18413368 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681 		JBrowse link
G Vegfc vascular endothelial growth factor C ISO associated with hypercholesterolemia;protein:increased expression:serum: RGD PMID:22206010 RGD:7483588 NCBI chr16:40,440,371...40,555,178
Ensembl chr16:40,440,207...40,555,576 		JBrowse link
G Vim vimentin ISO associated with arthritis,rheumatoid RGD PMID:21362765 RGD:6480618 NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212 		JBrowse link
CADASIL term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htra1 HtrA serine peptidase 1 ISO CTD Direct Evidence: marker/mechanism CTD NCBI chr 1:201,499,067...201,548,508
Ensembl chr 1:201,499,028...201,548,513 		JBrowse link
G Notch3 notch receptor 3 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy		 CTD
ClinVar		 PMID:15229130 PMID:24840674 PMID:25741868 PMID:26467025 PMID:29980472 NCBI chr 7:14,138,495...14,189,688
Ensembl chr 7:14,138,495...14,189,688 		JBrowse link
CADASIL 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Notch3 notch receptor 3 ISO ClinVar Annotator: match by term: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy type 1
ClinVar Annotator: match by term: Recurrent subcortical infarcts		 OMIM
ClinVar		 PMID:3484396 PMID:8878478 PMID:9388399 PMID:10227618 PMID:10371548 PMID:10712431 PMID:10716263 PMID:10854111 PMID:10969905 PMID:11102981 PMID:11486103 PMID:11559313 PMID:11571335 PMID:11706120 PMID:11715067 PMID:11755616 PMID:11757773 PMID:11771160 PMID:11784372 PMID:12136071 PMID:12146805 PMID:12196662 PMID:12482954 PMID:12721871 PMID:12754354 PMID:12810003 PMID:12821756 PMID:12821764 PMID:12861102 PMID:14714274 PMID:15229130 PMID:15287509 PMID:15350543 PMID:15364702 PMID:15378071 PMID:15694192 PMID:15776792 PMID:15827866 PMID:15834039 PMID:15857853 PMID:15981641 PMID:15995828 PMID:16009764 PMID:16580020 PMID:16717210 PMID:16730748 PMID:16864835 PMID:17122431 PMID:17135568 PMID:17323840 PMID:17390743 PMID:17879447 PMID:18765654 PMID:18803652 PMID:18948701 PMID:19006080 PMID:19043263 PMID:19174371 PMID:19180562 PMID:19242647 PMID:19245392 PMID:19252787 PMID:19259619 PMID:19293235 PMID:19359623 PMID:19417009 PMID:19528524 PMID:19542611 PMID:19576955 PMID:19825845 PMID:20038773 PMID:20071773 PMID:20167921 PMID:20301673 PMID:20851625 PMID:20857162 PMID:20935329 PMID:20981092 PMID:21387384 PMID:21555590 PMID:21616505 PMID:21737310 PMID:21852154 PMID:21940951 PMID:22006983 PMID:22019870 PMID:22082899 PMID:22153900 PMID:22159056 PMID:22218279 PMID:22367839 PMID:22373597 PMID:22623959 PMID:22664156 PMID:22795385 PMID:22878905 PMID:22936449 PMID:23025651 PMID:23412372 PMID:23584202 PMID:23602593 PMID:23639391 PMID:23649698 PMID:23844775 PMID:23847153 PMID:24033266 PMID:24086431 PMID:24139282 PMID:24344756 PMID:24425116 PMID:24480794 PMID:24886907 PMID:24929957 PMID:24936512 PMID:25033846 PMID:25260786 PMID:25326637 PMID:25344745 PMID:25412914 PMID:25604251 PMID:25623805 PMID:25692567 PMID:25741868 PMID:25801821 PMID:25819272 PMID:25834748 PMID:25870235 PMID:25929831 PMID:25959358 PMID:25973016 PMID:25980907 PMID:26002683 PMID:26261665 PMID:26270344 PMID:26308724 PMID:26368811 PMID:26467025 PMID:26646783 PMID:26671140 PMID:26715087 PMID:26806700 PMID:26850715 PMID:26856460 PMID:26889213 PMID:26894465 PMID:27174004 PMID:27293347 PMID:27350778 PMID:27423596 PMID:27770446 PMID:27844030 PMID:27881154 PMID:27884173 PMID:27890607 PMID:28334938 PMID:28479817 PMID:28492532 PMID:28601945 PMID:28710804 PMID:28991717 PMID:29188607 PMID:29449082 PMID:29980472 PMID:30199759 PMID:30279455 PMID:30311053 PMID:30338453 PMID:30402942 PMID:30656190 PMID:30954774 PMID:30956055 PMID:31028544 PMID:31792094 PMID:31799216 PMID:32581362 NCBI chr 7:14,138,495...14,189,688
Ensembl chr 7:14,138,495...14,189,688 		JBrowse link
CADASIL 2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htra1 HtrA serine peptidase 1 ISO ClinVar Annotator: match by term: Cerebral arteriopathy, autosomal dominant, with subcortical infarcts and leukoencephalopathy, type 2 ClinVar
OMIM		 PMID:19387015 PMID:25741868 PMID:26063658 PMID:30981321 PMID:32101834 PMID:32581362 NCBI chr 1:201,499,067...201,548,508
Ensembl chr 1:201,499,028...201,548,513 		JBrowse link
Cardiac Allograft Vasculopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F3 coagulation factor III, tissue factor IEP RGD PMID:9916935 RGD:11341701 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272 		JBrowse link
G Pdgfd platelet derived growth factor D ISO RGD PMID:19213942 RGD:9854642 NCBI chr 8:4,441,010...4,666,754
Ensembl chr 8:4,440,876...4,669,014 		JBrowse link
Cardiogenic Shock term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epo erythropoietin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19337937 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266 		JBrowse link
G Plat plasminogen activator, tissue type ISO CTD Direct Evidence: therapeutic CTD PMID:1430592 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889 		JBrowse link
G Sod2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21062213 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587 		JBrowse link
Carotid Atherosclerosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf21 fibroblast growth factor 21 ISO protein:increased expression:serum: RGD PMID:23887638 RGD:10401924 NCBI chr 1:101,595,579...101,596,822
Ensembl chr 1:101,595,579...101,596,822 		JBrowse link
G Pcsk5 proprotein convertase subtilisin/kexin type 5 ISO protein:increased expression:myofibroblast: RGD PMID:14970114 RGD:11556214 NCBI chr 1:236,031,988...236,313,858
Ensembl chr 1:236,031,988...236,313,858 		JBrowse link
G Sirt1 sirtuin 1 ISO mRNA, protein:decreased expression:carotid artery segment RGD PMID:23224247 RGD:9495924 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199 		JBrowse link
Carotid Intimal Medial Thickness 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pparg peroxisome proliferator-activated receptor gamma ISO OMIM NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380 		JBrowse link
carotid stenosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E ISO CTD Direct Evidence: marker/mechanism CTD PMID:17243563 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057 		JBrowse link
G Clec11a C-type lectin domain containing 11A ISO CTD Direct Evidence: marker/mechanism CTD PMID:26564003 NCBI chr 1:100,290,374...100,293,515
Ensembl chr 1:100,289,295...100,293,558 		JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase IDA RGD PMID:17936728 RGD:6483357 NCBI chr10:88,490,798...88,497,357
Ensembl chr10:88,490,798...88,497,356 		JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26564003 NCBI chr14:17,228,832...17,233,743
Ensembl chr14:17,228,856...17,234,712 		JBrowse link
G F2 coagulation factor II ISO DNA:SNP:3'-UTR:in men only (human) RGD PMID:15748240 RGD:5509914 NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031 		JBrowse link
G Fabp2 fatty acid binding protein 2 ISO RGD PMID:16013194 RGD:1582392 NCBI chr 2:227,080,912...227,083,654
Ensembl chr 2:227,080,924...227,083,501 		JBrowse link
G Faslg Fas ligand ISO RGD PMID:14739407 RGD:1582424 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705 		JBrowse link
G Gpx1 glutathione peroxidase 1 ISO RGD PMID:23426106 RGD:11352755 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522 		JBrowse link
G Il10 interleukin 10 no_association ISO RGD PMID:16804000 RGD:1598483 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392 		JBrowse link
G Il4 interleukin 4 treatment IEP RGD PMID:20498142 RGD:7829829 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531 		JBrowse link
G Itgb3 integrin subunit beta 3 ISO RGD PMID:15007005 RGD:1582450 NCBI chr10:92,667,869...92,783,413
Ensembl chr10:92,667,869...92,783,410 		JBrowse link
G Mfn2 mitofusin 2 treatment IMP RGD PMID:15322553 RGD:1304351 NCBI chr 5:164,684,244...164,715,414
Ensembl chr 5:164,684,509...164,714,145 		JBrowse link
G Mmp1 matrix metallopeptidase 1 ISO DNA:insertion, haplotype:promoter:g.-1607insG (human) RGD PMID:12364729 RGD:1580553 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591 		JBrowse link
G Mmp14 matrix metallopeptidase 14 ISO RGD PMID:16147977 RGD:1582575 NCBI chr15:33,074,441...33,083,666
Ensembl chr15:33,074,441...33,083,655 		JBrowse link
G Mmp2 matrix metallopeptidase 2 ISO RGD PMID:16147977 RGD:1582575 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611 		JBrowse link
G Mmp3 matrix metallopeptidase 3 ISO RGD PMID:12364729 RGD:1580553 NCBI chr 8:5,676,608...5,698,579
Ensembl chr 8:5,676,665...5,698,579 		JBrowse link
G Mt2A metallothionein 2A ISO DNA:snp:5' utr:g.+838C>G (human) RGD PMID:17622311 RGD:6483844 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO DNA:SNP:CDS:rs1801133, c.677C>T, p.A222V, in men only (human) RGD PMID:15748240 RGD:5509914 NCBI chr 5:164,844,642...164,864,360
Ensembl chr 5:164,845,925...164,860,910 		JBrowse link
G Pla2g7 phospholipase A2 group VII severity ISO RGD PMID:22075154 RGD:6482772 NCBI chr 9:19,935,754...19,978,013
Ensembl chr 9:19,935,768...19,978,013 		JBrowse link
G Procr protein C receptor IEP associated with Neointima RGD PMID:21903947 RGD:13515129 NCBI chr 3:151,285,321...151,289,581
Ensembl chr 3:151,285,249...151,289,595 		JBrowse link
G Spp1 secreted phosphoprotein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26564003 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901 		JBrowse link
G Tlr2 toll-like receptor 2 treatment IDA RGD PMID:22167462 RGD:7241095 NCBI chr 2:182,840,171...182,846,061
Ensembl chr 2:182,840,727...182,846,061 		JBrowse link
G Tlr4 toll-like receptor 4 treatment IDA RGD PMID:22167462 RGD:7241095 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052 		JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B ISO CTD Direct Evidence: marker/mechanism CTD PMID:26564003 NCBI chr 7:93,798,580...93,826,586
Ensembl chr 7:93,798,545...93,826,665 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 IMP RGD PMID:19958991 RGD:7240515 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619 		JBrowse link
central retinal vein occlusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Proc protein C, inactivator of coagulation factors Va and VIIIa treatment ISO RGD PMID:20688738 RGD:11100028 NCBI chr18:24,918,402...24,928,822
Ensembl chr18:24,918,398...24,929,091 		JBrowse link
G Serpinf1 serpin family F member 1 IEP protein:increased expression:neuroretina (rat) RGD PMID:21487926 RGD:5490120 NCBI chr10:62,241,750...62,254,145
Ensembl chr10:62,241,756...62,254,287 		JBrowse link
Cerebral Autosomal Recessive Arteriopathy with Subcortical Infarcts and Leukoencephalopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htra1 HtrA serine peptidase 1 ISO ClinVar Annotator: match by term: CARASIL
ClinVar Annotator: match by term: Cerebrovascular disease with thin skin, alopecia, and disc disease
ClinVar Annotator: match by term: Cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy
ClinVar Annotator: match by OMIM:600142		 OMIM
ClinVar		 PMID:11889251 PMID:18316707 PMID:19387015 PMID:21115960 PMID:21482952 PMID:22900900 PMID:23963851 PMID:24500651 PMID:24535794 PMID:25741868 PMID:25770224 PMID:25772074 PMID:25957642 PMID:26063658 PMID:26467025 PMID:27164673 PMID:32101834 PMID:32581362 NCBI chr 1:201,499,067...201,548,508
Ensembl chr 1:201,499,028...201,548,513 		JBrowse link
coronary artery disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 ISO RGD
GAD		 PMID:11086027, PMID:15118671 RGD:1600951, RGD:1331525 NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015 		JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 ISO DNA:nonsense mutation:exon:p.R1141X (3421C>T) (human) RGD PMID:12176944 RGD:11038788 NCBI chr 1:101,954,786...102,013,252
Ensembl chr 1:101,959,540...102,013,243 		JBrowse link
G Abcc9 ATP binding cassette subfamily C member 9 ISS OMIM:300464 | OMIM:607339 | OMIM:608316 | OMIM:608318 | OMIM:608320 | OMIM:608901 | OMIM:610938 | OMIM:610947 | OMIM:611139 | OMIM:612030 | OMIM:614293 | OMIM:614466 MouseDO NCBI chr 4:176,806,098...176,928,540
Ensembl chr 4:176,805,431...176,922,424 		JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11099417 PMID:11138003 NCBI chr 6:7,935,771...7,961,207
Ensembl chr 6:7,935,771...7,961,207 		JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11099417 NCBI chr 6:7,961,413...7,980,708
Ensembl chr 6:7,961,413...7,980,708 		JBrowse link
G Abo ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr 3:4,374,679...4,394,374
Ensembl chr 3:4,374,602...4,394,428 		JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 susceptibility ISO DNA:polymorphisms: :41A>G, 734C>T, IVS4-57_58ins48bp RGD PMID:16195894 RGD:1601112 NCBI chr 1:47,972,399...47,992,654
Ensembl chr 1:47,972,399...47,992,653 		JBrowse link
G Ace angiotensin I converting enzyme susceptibility ISO DNA:deletion:intron:IVS16+1464-1751del (human)
CTD Direct Evidence: marker/mechanism		 CTD PMID:14989558, PMID:12975417, PMID:15118671 RGD:1566498, RGD:1331525 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822 		JBrowse link
G Acp1 acid phosphatase 1 ISO RGD PMID:19246900 RGD:2313179 NCBI chr 6:49,836,064...49,851,714
Ensembl chr 6:49,836,075...49,851,714 		JBrowse link
G Adamts7 ADAM metallopeptidase with thrombospondin type 1 motif, 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr 8:97,535,777...97,575,661
Ensembl chr 8:97,535,777...97,575,655 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO protein:decreased expression:adipose tissue RGD PMID:17878891 RGD:5686802 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488 		JBrowse link
G Adrb3 adrenoceptor beta 3 no_association ISO DNA:missense mutation:cds:p.W64R (human)
DNA:missense mutation:cds:p.W64R rs4994 (human)		 RGD PMID:9126344, PMID:11229427 RGD:1559325, RGD:5684412 NCBI chr16:69,003,541...69,006,632
Ensembl chr16:69,003,868...69,006,632 		JBrowse link
G Adtrp androgen-dependent TFPI-regulating protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378986 NCBI chr17:22,619,913...22,688,296
Ensembl chr17:22,619,891...22,688,307 		JBrowse link
G Ager advanced glycosylation end product-specific receptor susceptibility ISO DNA:polymorphism:cds:p.G82S (human)
associated with Mucocutaneous Lymph Node Syndrome		 RGD PMID:20668462, PMID:22337222 RGD:6767569, RGD:8695960 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079 		JBrowse link
G Agt angiotensinogen ISO GAD PMID:15118671 RGD:1331525 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a susceptibility ISO DNA:polymorphism:3' utr:1166A>C RGD
GAD		 PMID:12975417, PMID:15118671 RGD:1566498, RGD:1331525 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077 		JBrowse link
G Ahsg alpha-2-HS-glycoprotein susceptibility ISO associated with Diabetes Mellitus, Type 2;DNA:SNPs RGD PMID:17062776, PMID:17062776 RGD:1625792, RGD:1625792 NCBI chr11:81,711,269...81,717,594 JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO RGD PMID:18054314 RGD:5509083 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258 		JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein ISO DNA:snps:multiple (human) RGD PMID:19596330 RGD:2313883 NCBI chr12:6,854,930...6,879,112
Ensembl chr12:6,854,920...6,879,154 		JBrowse link
G Angptl4 angiopoietin-like 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27135400 NCBI chr 7:18,627,814...18,634,043
Ensembl chr 7:18,627,808...18,634,079 		JBrowse link
G Anks1a ankyrin repeat and sterile alpha motif domain containing 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr20:7,484,550...7,636,498
Ensembl chr20:7,484,550...7,636,497 		JBrowse link
G Apcs amyloid P component, serum ISO CTD Direct Evidence: marker/mechanism CTD PMID:12714198 NCBI chr13:91,426,621...91,427,417
Ensembl chr13:91,426,479...91,427,575 		JBrowse link
G Aph1b aph-1 homolog B, gamma secretase subunit ISO DNA:SNP:CDS:p.F217L (rs1047552) (human) RGD PMID:18987747 RGD:13703124 NCBI chr 8:72,508,008...72,598,921
Ensembl chr 8:72,476,425...72,629,265 		JBrowse link
G Apoa1 apolipoprotein A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27135400, PMID:2128269, PMID:15118671 RGD:1601188, RGD:1331525 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875 		JBrowse link
G Apoa2 apolipoprotein A2 ISO protein:decreased expression:serum RGD PMID:17923573 RGD:2313956 NCBI chr13:89,596,872...89,598,805
Ensembl chr13:89,597,138...89,598,802 		JBrowse link
G Apoa5 apolipoprotein A5 no_association ISO DNA:polymorphism:promoter:-1131T>C (human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphism:promoter:-1131T>C, c.56C>G (human)		 CTD PMID:24097064, PMID:15177130, PMID:15306190 RGD:2313322, RGD:1578412 NCBI chr 8:50,559,079...50,561,720
Ensembl chr 8:50,559,126...50,561,736 		JBrowse link
G Apob apolipoprotein B no_association ISO RGD
GAD		 PMID:9585673, PMID:15118671, PMID:1732399 RGD:1578418, RGD:1331525, RGD:1578417 NCBI chr 6:33,176,826...33,216,381
Ensembl chr 6:33,176,778...33,224,997 		JBrowse link
G Apoc3 apolipoprotein C3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24097064, PMID:14709372, PMID:15118671, PMID:15059615 RGD:1578443, RGD:1331525, RGD:1626412 NCBI chr 8:50,529,318...50,531,498
Ensembl chr 8:50,529,318...50,531,498 		JBrowse link
G Apoe apolipoprotein E susceptibility ISO
IMP		 DNA:snp, missense mutation:promoter, cds:g.-219G>T, p.C112R (human)
associated with Diabetes Mellitus, Non-Insulin Dependent;DNA:SNP:promoter:-219G>T (human)
DNA:missense mutation:cds:p.C112R (human)		 RGD
GAD		 PMID:14563588, PMID:28808185, PMID:15118671, PMID:15059615, PMID:12860263 RGD:1580039, RGD:13703132, RGD:1331525, RGD:1626412, RGD:1578449 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057 		JBrowse link
G Apom apolipoprotein M susceptibility ISO DNA:SNP:promoter:g.-778T>C(rs805296)(human) RGD PMID:17674965 RGD:2314241 NCBI chr20:5,120,473...5,123,073
Ensembl chr20:5,120,474...5,123,073 		JBrowse link
G Ar androgen receptor ISO GAD PMID:15118671 RGD:1331525 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026 		JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22751097 NCBI chr 7:41,114,606...41,223,138
Ensembl chr 7:41,114,697...41,220,579 		JBrowse link
G Bche butyrylcholinesterase susceptibility ISO DNA:polymorphism: :p.A539T (human) RGD PMID:17852836 RGD:2306777 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395 		JBrowse link
G Brinp3 BMP/retinoic acid inducible neural specific 3 ISO DNA:SNP: :rs12732361(human), associated with male. RGD PMID:27461004 RGD:14398490 NCBI chr13:63,526,486...63,959,390
Ensembl chr13:63,526,486...63,959,332 		JBrowse link
G Btnl2 butyrophilin-like 2 susceptibility ISO associated with Mucocutaneous Lymph Node Syndrome; DNA:SNP: :rs 2395158(human) RGD PMID:19882345 RGD:9685030 NCBI chr20:4,140,184...4,156,365
Ensembl chr20:4,141,878...4,154,978 		JBrowse link
G Cbs cystathionine beta synthase ISO CBS variant c.844ins68 RGD PMID:12855221 RGD:1600626 NCBI chr20:10,361,987...10,386,663
Ensembl chr20:10,361,988...10,386,751 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 IEP
ISO		 protein:increased expression:myocardium (rat)
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Coronary artery disease, modifier of
protein:increased expression:serum (human)		 CTD
ClinVar		 PMID:11500196 PMID:15466648 PMID:16352737 PMID:16596675 PMID:16934270 PMID:18940815, PMID:16297799, PMID:9537339 RGD:8549513, RGD:8549577 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870 		JBrowse link
G Ccl26 C-C motif chemokine ligand 26 susceptibility ISO protein:decreased expression:plasma (human) RGD PMID:16620281 RGD:11081161 NCBI chr12:24,157,182...24,161,870
Ensembl chr12:24,158,766...24,161,869 		JBrowse link
G Ccr1 C-C motif chemokine receptor 1 ISO RGD PMID:12742282 RGD:5508477 NCBI chr 8:132,996,646...133,002,201
Ensembl chr 8:132,996,649...133,002,201 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 ISO RGD PMID:12426226 RGD:1581178
G Ccr5 C-C motif chemokine receptor 5 IEP mRNA:increased expression:heart (rat) RGD PMID:17449418 RGD:4890438 NCBI chr 8:133,192,398...133,215,599
Ensembl chr 8:133,197,032...133,215,614 		JBrowse link
G Cd14 CD14 molecule no_association ISO DNA:SNP:promoter RGD PMID:18157711 RGD:2314154 NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153 		JBrowse link
G Cd40lg CD40 ligand ISO
IEP		 protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
associated with Mucocutaneous Lymph Node Syndrome;DNA:SNP: :rs4810485 (human)
protein:increased expression:coronary artery, serum
associated with Kidney Failure, Chronic		 CTD PMID:16368305, PMID:17635572, PMID:22645426, PMID:23819214, PMID:16494885 RGD:2314209, RGD:8547776, RGD:7248750, RGD:7248436 NCBI chr  X:159,703,703...159,714,886
Ensembl chr  X:159,703,578...159,716,562 		JBrowse link
G Cdh5 cadherin 5 ISO RGD PMID:14695457 RGD:1598391 NCBI chr19:1,025,122...1,074,333
Ensembl chr19:1,023,683...1,074,365 		JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B ISO CTD Direct Evidence: marker/mechanism CTD PMID:23104008 NCBI chr 5:107,834,353...107,857,428
Ensembl chr 5:107,845,951...107,858,104 		JBrowse link
G Cela2a chymotrypsin like elastase 2A ISO ClinVar Annotator: match by term: Coronary artery disease ClinVar PMID:31358993 NCBI chr 5:160,374,031...160,383,782
Ensembl chr 5:160,374,031...160,383,782 		JBrowse link
G Chi3l1 chitinase 3 like 1 ISO protein:increased secretion:serum (human) RGD PMID:17627189 RGD:4892665 NCBI chr13:51,022,844...51,030,797
Ensembl chr13:51,022,681...51,030,802 		JBrowse link
G Clcn6 chloride voltage-gated channel 6 susceptibility ISO DNA:SNP: :rs3737964(human) RGD PMID:26740945 RGD:14696742 NCBI chr 5:164,811,815...164,844,554
Ensembl chr 5:164,811,816...164,844,586 		JBrowse link
G Clu clusterin ISO associated with Mucocutaneous Lymph Node Syndrome;protein:decreased expression:plasma RGD PMID:20711835 RGD:9068393 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857 		JBrowse link
G Crp C-reactive protein ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:serum
CTD Direct Evidence: marker/mechanism		 CTD PMID:24868163, PMID:19615354 RGD:2313344 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713 		JBrowse link
G Cst3 cystatin C ISO protein:increased expression:serum (human) RGD PMID:17983622 RGD:2314352 NCBI chr 3:143,219,671...143,223,544
Ensembl chr 3:143,219,686...143,223,615 		JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 ISS OMIM:300464 | OMIM:607339 | OMIM:608316 | OMIM:608318 | OMIM:608320 | OMIM:608901 | OMIM:610938 | OMIM:610947 | OMIM:611139 | OMIM:612030 | OMIM:614293 | OMIM:614466 MouseDO NCBI chr 8:128,740,756...128,754,514
Ensembl chr 8:128,740,756...128,754,514 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891 		JBrowse link
G Cyba cytochrome b-245 alpha chain ISO RGD
GAD		 PMID:14709372, PMID:15118671 RGD:1578443, RGD:1331525 NCBI chr19:55,249,634...55,257,824
Ensembl chr19:55,249,616...55,257,876 		JBrowse link
G Ddah2 dimethylarginine dimethylaminohydrolase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17267746 NCBI chr20:5,049,260...5,052,573
Ensembl chr20:5,049,496...5,052,585 		JBrowse link
G Ece1 endothelin converting enzyme 1 ISO protein:increased expression:smooth muscle cell,macrophage RGD PMID:10973835, PMID:8994440 RGD:1580909, RGD:7244168 NCBI chr 5:156,215,469...156,318,652
Ensembl chr 5:156,215,417...156,318,671 		JBrowse link
G Edn1 endothelin 1 treatment
severity		 ISO
IMP		 protein:increased expression:atherosclerotic lesions (human)
associated with Hypertension;DNA:missense mutation:cds:p.L198N (human)		 RGD PMID:7968078, PMID:11927217, PMID:18923236 RGD:4144886, RGD:8662294, RGD:8661705 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324 		JBrowse link
G Eng endoglin severity ISO protein:increased expression:plasma (human) RGD PMID:21667051 RGD:7248776 NCBI chr 3:11,679,530...11,717,486
Ensembl chr 3:11,679,530...11,717,485 		JBrowse link
G Ephx2 epoxide hydrolase 2 ISO RGD PMID:14732757 RGD:1580982 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279 		JBrowse link
G Epo erythropoietin ISO CTD Direct Evidence: therapeutic CTD PMID:25245553 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266 		JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit susceptibility ISO DNA:SNP: :rs13181(human) RGD PMID:27566080 RGD:12880440 NCBI chr 1:80,293,574...80,307,334
Ensembl chr 1:80,293,566...80,307,344 		JBrowse link
G Esr1 estrogen receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:9396482 PMID:20559769, PMID:16159931 RGD:1580335 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796 		JBrowse link
G Esr2 estrogen receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20559769, PMID:16099331 RGD:1581014 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251 		JBrowse link
G F2 coagulation factor II treatment ISO RGD PMID:14961168 RGD:10449426 NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031 		JBrowse link
G F7 coagulation factor VII ISO associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:increased activity:plasma (human)
DNA:polymorphisms:cds:R353Q (human)		 RGD PMID:10599031, PMID:8522401, PMID:11334615 RGD:2312400, RGD:2312408, RGD:2312397 NCBI chr16:81,824,610...81,834,923
Ensembl chr16:81,824,111...81,834,945 		JBrowse link
G Fabp2 fatty acid binding protein 2 ISO associated with Diabetes Mellitus, Type 2 (MeSH:D003924) RGD PMID:15059615 RGD:1626412 NCBI chr 2:227,080,912...227,083,654
Ensembl chr 2:227,080,924...227,083,501 		JBrowse link
G Fcgr2a Fc fragment of IgG receptor IIa ISO DNA:polymorphism: :p.H131R (human) RGD PMID:20973705 RGD:5147917 NCBI chr13:91,146,878...91,163,691
Ensembl chr13:91,168,973...91,198,036
Ensembl chr13:91,168,973...91,198,036 		JBrowse link
G Fcgr3a Fc fragment of IgG receptor IIIa susceptibility ISO DNA:SNP:exon:p.F158V (rs396991)(human) RGD PMID:15910853 RGD:5508464 NCBI chr13:89,385,775...89,396,047
Ensembl chr13:89,385,859...89,396,051 		JBrowse link
G Fgb fibrinogen beta chain ISO RGD PMID:8565160 RGD:1580382 NCBI chr 2:182,028,044...182,035,026
Ensembl chr 2:182,027,115...182,038,178 		JBrowse link
G Fgf2 fibroblast growth factor 2 ISO associated with Diabetes Mellitus RGD PMID:14585103 RGD:2315879 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681 		JBrowse link
G Gck glucokinase susceptibility ISO DNA:SNP:promoter:-30G>A (human) RGD PMID:15173029 RGD:2301876 NCBI chr14:86,149,146...86,191,589
Ensembl chr14:86,148,928...86,190,659 		JBrowse link
G Gdf15 growth differentiation factor 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20855664 NCBI chr16:20,555,395...20,557,978
Ensembl chr16:20,555,395...20,557,978 		JBrowse link
G Gja4 gap junction protein, alpha 4 ISO RGD PMID:15059615 RGD:1626412 NCBI chr 5:145,374,688...145,377,221
Ensembl chr 5:145,374,690...145,377,221 		JBrowse link
G Gnb3 G protein subunit beta 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16141801 NCBI chr 4:157,352,558...157,359,237
Ensembl chr 4:157,352,372...157,358,262 		JBrowse link
G Gpx1 glutathione peroxidase 1 ISO cardiovascular complications in type 2 diabetics
DNA:repeat:exon		 RGD PMID:16338763, PMID:12655278 RGD:1600708, RGD:1600677 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522 		JBrowse link
G Gsr glutathione-disulfide reductase ISO cardiovascular complications in type 2 diabetics RGD PMID:16338763 RGD:1600708 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 susceptibility ISO associated with Diabetes Mellitus, Non-Insulin-Dependent
DNA:deletion		 RGD PMID:19102712, PMID:16620396 RGD:2306625, RGD:2306633 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306 		JBrowse link
G Gstt1 glutathione S-transferase theta 1 susceptibility ISO associated with Diabetes Mellitus, Non-Insulin-Dependent
DNA:deletion		 RGD PMID:19102712, PMID:16620396 RGD:2306625, RGD:2306633 NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526 		JBrowse link
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22751097 NCBI chr 2:181,045,694...181,103,321
Ensembl chr 2:181,045,703...181,102,918 		JBrowse link
G Hectd4 HECT domain E3 ubiquitin protein ligase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22751097 NCBI chr12:40,712,078...40,860,930
Ensembl chr12:40,713,841...40,822,159 		JBrowse link
G Hfe homeostatic iron regulator no_association ISO RGD PMID:12746412 RGD:1582673 NCBI chr17:43,661,276...43,669,327
Ensembl chr17:43,661,222...43,669,985 		JBrowse link
G Hgf hepatocyte growth factor ISO RGD PMID:11669408 RGD:8548610 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362 		JBrowse link
G Hhipl1 HHIP-like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr 6:132,218,583...132,242,852
Ensembl chr 6:132,219,088...132,240,356 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase ISO RGD PMID:12742282 RGD:5508477 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654 		JBrowse link
G Hmox1 heme oxygenase 1 no_association
susceptibility		 ISO DNA:repeat:promoter
CTD Direct Evidence: marker/mechanism		 CTD PMID:12136229, PMID:14691581, PMID:12377749, PMID:12136229 RGD:1580470, RGD:1580454, RGD:1598401 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456 		JBrowse link
G Hp haptoglobin ISO protein:increased expression:serum RGD PMID:884791 RGD:1626363 NCBI chr19:42,096,255...42,100,805
Ensembl chr19:42,097,995...42,100,804 		JBrowse link
G Hs3st1 heparan sulfate-glucosamine 3-sulfotransferase 1 ISO ClinVar Annotator: match by term: Coronary artery disease ClinVar PMID:15266341 PMID:15965027 PMID:16024819 PMID:16410828 PMID:17179217 PMID:17558387 PMID:17568005 PMID:19122651 PMID:19303047 PMID:19858363 PMID:21152010 PMID:22090374 PMID:28126521 NCBI chr14:75,880,410...75,881,346
Ensembl chr14:75,852,060...75,882,693 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 severity ISO RGD PMID:11222468 RGD:1624218 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956 		JBrowse link
G Il10 interleukin 10 no_association
susceptibility		 ISO DNA:SNPs:promoter:-592C>A (rs1800872), -819C>T (rs1800871) (human)
DNA:SNP:promoter:-1082A>G (rs1800896) (human)		 RGD PMID:16460885, PMID:29525679, PMID:29525679 RGD:1598621, RGD:14975129, RGD:14975129 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392 		JBrowse link
G Il15 interleukin 15 ISO associated with Hypertension;protein:increased expression:serum RGD PMID:16109314 RGD:1626610 NCBI chr19:23,542,606...23,624,366
Ensembl chr19:23,542,889...23,554,594 		JBrowse link
G Il1b interleukin 1 beta ISO mRNA:increased expression:peripheral blood (human) RGD PMID:22780915 RGD:7175093 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726 		JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 severity ISO DNA:polymorphisms: :-27307T>A, -27614C>A (human) RGD PMID:20602249 RGD:5144241 NCBI chr 9:47,133,483...47,184,316
Ensembl chr 9:47,134,034...47,182,170 		JBrowse link
G Il6 interleukin 6 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:increased expression:extracellular space (human) RGD PMID:19368923 RGD:2307251 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807 		JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20524934 NCBI chr  X:156,716,469...156,726,367
Ensembl chr  X:156,716,604...156,725,977 		JBrowse link
G Irs1 insulin receptor substrate 1 ISO DNA:polymorphism:exon:G972R
CTD Direct Evidence: marker/mechanism		 CTD PMID:10591678, PMID:10591678 RGD:1624974 NCBI chr 9:88,033,668...88,086,488
Ensembl chr 9:88,033,668...88,086,488 		JBrowse link
G Itga2 integrin subunit alpha 2 no_association ISO RGD PMID:15227729 RGD:1582294 NCBI chr 2:46,996,904...47,097,011
Ensembl chr 2:47,000,323...47,096,961 		JBrowse link
G Jcad junctional cadherin 5 associated ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378988 NCBI chr17:55,667,754...55,709,738
Ensembl chr17:55,670,331...55,709,740 		JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 ISS OMIM:300464 | OMIM:607339 | OMIM:608316 | OMIM:608318 | OMIM:608320 | OMIM:608901 | OMIM:610938 | OMIM:610947 | OMIM:611139 | OMIM:612030 | OMIM:614293 | OMIM:614466 MouseDO NCBI chr 4:176,783,287...176,789,143
Ensembl chr 4:176,782,498...176,789,304 		JBrowse link
G Khdc3 KH domain containing 3, subcortical maternal complex member ISS OMIM:300464 | OMIM:607339 | OMIM:608316 | OMIM:608318 | OMIM:608320 | OMIM:608901 | OMIM:610938 | OMIM:610947 | OMIM:611139 | OMIM:612030 | OMIM:614293 | OMIM:614466 MouseDO NCBI chr 8:79,781,941...79,783,845
Ensembl chr 8:79,781,983...79,783,592 		JBrowse link
G Kl Klotho ISO CTD Direct Evidence: marker/mechanism
DNA:SNP:promoter: -G395>A (human)		 CTD PMID:12669274, PMID:16979405, PMID:16579981 RGD:1581721, RGD:1581723 NCBI chr12:942,974...987,206
Ensembl chr12:943,006...987,551 		JBrowse link
G Ldlr low density lipoprotein receptor no_association ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 PMID:27135400, PMID:16459141 RGD:1581823 NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903 		JBrowse link
G Lepr leptin receptor susceptibility ISO DNA:SNP:cds:p.Q223R(human) RGD PMID:27257426 RGD:21079462 NCBI chr 5:120,503,475...120,682,281
Ensembl chr 5:120,564,645...120,682,221 		JBrowse link
G Lipa lipase A, lysosomal acid type ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378988 NCBI chr 1:252,816,536...252,959,348
Ensembl chr 1:252,816,527...252,849,904 		JBrowse link
G Lipc lipase C, hepatic type no_association ISO associated with Diabetes Mellitus, Insulin-Dependent; DNA:transition:promoter:-480C>T (human) RGD
GAD		 PMID:11916946, PMID:15118671, PMID:12689525, PMID:15099346 RGD:2308839, RGD:1331525, RGD:1600664, RGD:1600663 NCBI chr 8:77,272,582...77,398,485
Ensembl chr 8:77,272,570...77,398,248 		JBrowse link
G Lipg lipase G, endothelial type ISO RGD PMID:16354105 RGD:1580865 NCBI chr18:70,903,528...70,924,434
Ensembl chr18:70,901,710...70,924,708 		JBrowse link
G Lmod1 leiomodin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28530674 NCBI chr13:52,147,099...52,189,835
Ensembl chr13:52,147,555...52,190,228 		JBrowse link
G LOC102551309 uncharacterized LOC102551309 ISO DNA:SNP: :rs56001051(human) RGD PMID:31175347 RGD:14696712 NCBI chr 5:164,875,558...164,885,606
Ensembl chr 5:164,874,832...164,883,933 		JBrowse link
G Lox lysyl oxidase IDA RGD PMID:12393934 RGD:1581886 NCBI chr18:47,500,320...47,577,819
Ensembl chr18:47,500,330...47,577,819 		JBrowse link
G Lpl lipoprotein lipase ISO RGD PMID:8641022 RGD:1580537 NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496 		JBrowse link
G Lrp6 LDL receptor related protein 6 ISS OMIM:300464 | OMIM:607339 | OMIM:608316 | OMIM:608318 | OMIM:608320 | OMIM:608901 | OMIM:610938 | OMIM:610947 | OMIM:611139 | OMIM:612030 | OMIM:614293 | OMIM:614466 MouseDO NCBI chr 4:168,194,054...168,323,962
Ensembl chr 4:168,194,927...168,323,751 		JBrowse link
G Lrp8 LDL receptor related protein 8 no_association
onset		 ISO DNA:missense mutation:cds:p.R952Q (human) RGD PMID:18592168, PMID:17847002 RGD:2306125, RGD:2306124 NCBI chr 5:127,404,348...127,476,636
Ensembl chr 5:127,404,450...127,476,641 		JBrowse link
G Lta lymphotoxin alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:15266304, PMID:15973460 RGD:1580414 NCBI chr20:4,851,889...4,854,677
Ensembl chr20:4,852,496...4,854,677 		JBrowse link
G Lum lumican ISO RGD PMID:11890723 RGD:1582121 NCBI chr 7:38,820,058...38,826,862
Ensembl chr 7:38,819,771...38,826,862 		JBrowse link
G Mef2a myocyte enhancer factor 2a ISO
ISS		 OMIM:300464 | OMIM:607339 | OMIM:608316 | OMIM:608318 | OMIM:608320 | OMIM:608901 | OMIM:610938 | OMIM:610947 | OMIM:611139 | OMIM:612030 | OMIM:614293 | OMIM:614466 MouseDO PMID:15811259 RGD:1580548 NCBI chr 1:128,207,715...128,341,681
Ensembl chr 1:128,209,971...128,341,263 		JBrowse link
G Mia3 MIA SH3 domain ER export factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr13:101,727,434...101,770,127
Ensembl chr13:101,727,935...101,761,541 		JBrowse link
G Mir146a microRNA 146a ISO CTD Direct Evidence: marker/mechanism
miRNA:increased expression:peripheral blood mononuclear cell, plasma		 CTD PMID:20524934, PMID:31866771 RGD:21081515 NCBI chr10:28,962,476...28,962,570
Ensembl chr10:28,962,476...28,962,570 		JBrowse link
G Mir146b microRNA 146b ISO CTD Direct Evidence: marker/mechanism CTD PMID:20524934 NCBI chr 1:266,089,488...266,089,575
Ensembl chr 1:266,089,488...266,089,575 		JBrowse link
G Mir155 microRNA 155 ISO miRNA:decreased expression:peripheral blood mononuclear cell, plasma RGD PMID:31866771 RGD:21081515 NCBI chr11:24,176,603...24,176,667
Ensembl chr11:24,176,603...24,176,667 		JBrowse link
G Mir21 microRNA 21 ISO miRNA:increased expression:peripheral blood mononuclear cell, plasma RGD PMID:31866771 RGD:21081515 NCBI chr10:73,902,210...73,902,301
Ensembl chr10:73,902,210...73,902,301 		JBrowse link
G Mir223 microRNA 223 treatment ISO RGD PMID:25350775 RGD:11076984 NCBI chr  X:65,367,812...65,367,921
Ensembl chr  X:65,367,812...65,367,921 		JBrowse link
G Mmp1 matrix metallopeptidase 1 severity ISO DNA:insertion, haplotype:promoter:g.-1607insG rs799750 (human) RGD PMID:15619398, PMID:17893005 RGD:1582527, RGD:7207049 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591 		JBrowse link
G Mmp12 matrix metallopeptidase 12 susceptibility ISO RGD PMID:10807873 RGD:1582366 NCBI chr 8:5,594,717...5,616,494
Ensembl chr 8:5,606,592...5,616,493 		JBrowse link
G Mmp3 matrix metallopeptidase 3 ISO DNA:insertion, haplotype:promoter:g.-1613insA rs3025058 (human)
CTD Direct Evidence: marker/mechanism
associated with Mucocutaneous Lymph Node Syndrome		 CTD PMID:8662692, PMID:17893005, PMID:16100452 RGD:7207049, RGD:8693322 NCBI chr 8:5,676,608...5,698,579
Ensembl chr 8:5,676,665...5,698,579 		JBrowse link
G Mmp9 matrix metallopeptidase 9 susceptibility
treatment		 ISO
IEP		 RGD PMID:15191941, PMID:26261622 RGD:1582644, RGD:11344965 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520 		JBrowse link
G Mras muscle RAS oncogene homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr 8:107,629,028...107,656,851
Ensembl chr 8:107,629,028...107,681,512 		JBrowse link
G Mrps6 mitochondrial ribosomal protein S6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr11:32,208,246...32,263,999
Ensembl chr11:32,211,115...32,263,899 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase no_association
susceptibility		 ISO DNA:transition:cds:g.677C>T (human) RGD PMID:15648053, PMID:12387655 RGD:1580579, RGD:6893453 NCBI chr 5:164,844,642...164,864,360
Ensembl chr 5:164,845,925...164,860,910 		JBrowse link
G Nampt nicotinamide phosphoribosyltransferase ISO RGD PMID:17283255 RGD:1642340 NCBI chr 6:52,122,085...52,156,473
Ensembl chr 6:52,122,085...52,156,472 		JBrowse link
G Nat2 N-acetyltransferase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21572414 NCBI chr16:23,960,709...23,991,570
Ensembl chr16:23,961,067...23,991,570 		JBrowse link
G Ngf nerve growth factor ISO RGD PMID:11935372 RGD:1580935 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453 		JBrowse link
G Ngfr nerve growth factor receptor ISO RGD PMID:11935372 RGD:1580935 NCBI chr10:83,389,828...83,408,061
Ensembl chr10:83,389,847...83,408,061 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 ISO DNA:polymorphisms: :p.G908R, 3020_3021insC (human) RGD PMID:21565239 RGD:5508725 NCBI chr19:19,342,061...19,389,366
Ensembl chr19:19,332,594...19,377,492 		JBrowse link
G Nos2 nitric oxide synthase 2 ISO associated with Mucocutaneous Lymph Node Syndrome; protein:increased expression:neutrophil, monocyte RGD PMID:14764920 RGD:1580941 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190 		JBrowse link
G Nos3 nitric oxide synthase 3 susceptibility ISO DNA:duplication:intron:IVS4?-?+27 (human)
CTD Direct Evidence: marker/mechanism
DNA:snp:promoter:g.-786T>C (human)
DNA:snp:cds:c.894G>T (human)		 CTD PMID:10510054 PMID:14989558 PMID:17267746 PMID:19696404, PMID:8564837, PMID:19761682, PMID:16284093 RGD:7421529, RGD:7771578, RGD:7771567 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410 		JBrowse link
G Nppa natriuretic peptide A ISO DNA:snp:cds:c.2238T>C (human)
associated with Diabetes Mellitus, Type 2;DNA:SNP:exon: 2238T>C,rs5065 (human)		 RGD PMID:12514664, PMID:22170009 RGD:1579982, RGD:7247716 NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705 		JBrowse link
G Nppb natriuretic peptide B ISO CTD Direct Evidence: marker/mechanism CTD PMID:18022110 NCBI chr 5:164,796,176...164,797,538
Ensembl chr 5:164,796,185...164,797,531 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 ISO DNA:missense mutation:cds:p.N363S (human) RGD PMID:12623935 RGD:1580790 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647 		JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 severity ISO DNA:snp:3' utr:T>C (human)
DNA:missense mutation:cds:p.K167N (human)		 RGD PMID:12810610, PMID:15562935 RGD:1580995, RGD:1580994 NCBI chr 4:163,239,853...163,261,937
Ensembl chr 4:163,239,849...163,261,958 		JBrowse link
G Pappa1 pappalysin 1 severity ISO CTD Direct Evidence: marker/mechanism CTD PMID:11586954, PMID:16055491 RGD:1642327 NCBI chr 5:80,919,932...81,153,904
Ensembl chr 5:80,920,568...81,150,940 		JBrowse link
G Parl presenilin associated, rhomboid-like susceptibility ISO DNA:missense mutation:cds:p.L262V (human) RGD PMID:18758826 RGD:12902623 NCBI chr11:84,517,368...84,544,463
Ensembl chr11:84,517,368...84,544,462 		JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 PMID:27135400 NCBI chr 5:126,031,368...126,053,726
Ensembl chr 5:126,031,368...126,053,726 		JBrowse link
G Pdgfd platelet derived growth factor D ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378988 NCBI chr 8:4,441,010...4,666,754
Ensembl chr 8:4,440,876...4,669,014 		JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 no_association ISO DNA:missense mutations:cds:p.N536S, p.G670R (human)
CTD Direct Evidence: marker/mechanism
DNA:missense mutation:cds:p.L125V (human)
DNA:polymorphism:5' utr:g.53G>A (human)		 CTD PMID:28530674, PMID:11795274, PMID:10780329, PMID:12732396 RGD:2311656, RGD:6771225, RGD:1581010 NCBI chr10:94,850,971...94,913,202 JBrowse link
G Phactr1 phosphatase and actin regulator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 PMID:22751097 PMID:26098115 NCBI chr17:23,245,423...23,761,207 JBrowse link
G Pla2g7 phospholipase A2 group VII disease_progression
susceptibility		 ISO DNA:polymorphism: :p.A379V (human) RGD PMID:17070179, PMID:15115767 RGD:6482777, RGD:6482781 NCBI chr 9:19,935,754...19,978,013
Ensembl chr 9:19,935,768...19,978,013 		JBrowse link
G Plpp3 phospholipid phosphatase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr 5:124,690,214...124,765,499
Ensembl chr 5:124,690,214...124,765,498 		JBrowse link
G Pnpla3 patatin-like phospholipase domain containing 3 ISO associated with type 2 diabetes mellitus;DNA:SNP: :rs738409 (p.I148M) (human) RGD PMID:31377187 RGD:14981594 NCBI chr 7:125,034,760...125,056,165
Ensembl chr 7:125,034,764...125,055,976 		JBrowse link
G Pon1 paraoxonase 1 susceptibility ISO DNA:missense mutation:cds:p.Q192R (human)
CTD Direct Evidence: marker/mechanism|therapeutic
ClinVar Annotator: match by term: Coronary artery spasm 2, susceptibility to
protein:increased activity:serum (human)		 CTD
ClinVar		 PMID:7916578 PMID:8098250 PMID:8675673 PMID:8770857 PMID:9215303 PMID:9385372 PMID:9443884 PMID:11238489 PMID:11810302 PMID:11888590 PMID:12082503 PMID:15241482 PMID:21170047 PMID:21629682, PMID:10729395, PMID:15785307, PMID:11917194 RGD:1580196, RGD:8547681, RGD:1580203 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372 		JBrowse link
G Pon2 paraoxonase 2 severity ISO DNA:missense mutation:cds:p.C311S (human) RGD PMID:12454802 RGD:1580217 NCBI chr 4:30,344,705...30,380,119
Ensembl chr 4:30,344,709...30,380,119 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha susceptibility ISO DNA:snp:intron: (human) RGD PMID:16043164 RGD:1580228 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma ISO protein:decreased expression:carotid artery, macrophage, smooth muscle cell (human) RGD PMID:21709632 RGD:8552814 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380 		JBrowse link
G Prkag2 protein kinase AMP-activated non-catalytic subunit gamma 2 ISO ClinVar Annotator: match by term: Coronary artery disease ClinVar PMID:25741868 PMID:28492532 NCBI chr 4:6,559,153...6,799,888
Ensembl chr 4:6,559,545...6,799,632 		JBrowse link
G Procr protein C receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:28530674 NCBI chr 3:151,285,321...151,289,581
Ensembl chr 3:151,285,249...151,289,595 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14642682 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335 		JBrowse link
G Pth parathyroid hormone ISO protein:increased expression:serum (human) RGD PMID:23460043 RGD:7242420 NCBI chr 1:178,215,829...178,218,761
Ensembl chr 1:178,215,829...178,218,761 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 ISO DNA: snp: cds: rs2476601 RGD PMID:21846984 RGD:6484553 NCBI chr 2:206,342,066...206,390,348
Ensembl chr 2:206,342,066...206,390,348 		JBrowse link
G Sele selectin E susceptibility ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:mutation: :p.S128R (human) RGD PMID:17578587 RGD:2313596 NCBI chr13:82,355,234...82,365,323
Ensembl chr13:82,355,471...82,365,341 		JBrowse link
G Selp selectin P ISO ClinVar Annotator: match by term: Premature coronary artery disease ClinVar NCBI chr13:82,428,914...82,464,629
Ensembl chr13:82,429,063...82,464,628 		JBrowse link
G Serpina1 serpin family A member 1 ISO protein:increased expression:serum RGD PMID:7832094 RGD:1643149 NCBI chr 6:127,610,241...127,632,265
Ensembl chr 6:127,610,243...127,632,265 		JBrowse link
G Serpine1 serpin family E member 1 susceptibility ISO DNA:insertion:promoter: (human) RGD PMID:9484978 RGD:1580190 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482 		JBrowse link
G Serpinf2 serpin family F member 2 ISO RGD PMID:9184412 RGD:1625532 NCBI chr10:62,264,247...62,272,353
Ensembl chr10:62,264,788...62,273,119 		JBrowse link
G Sh2b3 SH2B adaptor protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr12:40,261,990...40,265,757
Ensembl chr12:40,244,081...40,265,757 		JBrowse link
G Soat2 sterol O-acyltransferase 2 susceptibility ISO DNA:polymorphisms: :p.E41G, p.T734I, IVS4-57_-58ins48bp (human) RGD PMID:16195894 RGD:1601112 NCBI chr 7:143,754,892...143,767,989
Ensembl chr 7:143,754,892...143,767,989 		JBrowse link
G Sod1 superoxide dismutase 1 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent RGD PMID:16338763 RGD:1600708 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862 		JBrowse link
G Sod3 superoxide dismutase 3 ISO RGD PMID:10811593 RGD:1580853 NCBI chr14:60,958,583...60,971,143
Ensembl chr14:60,958,592...60,964,324 		JBrowse link
G Sort1 sortilin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr 2:211,078,092...211,156,312
Ensembl chr 2:211,078,334...211,156,312 		JBrowse link
G Spp1 secreted phosphoprotein 1 ISO In type 2 diabetic patients RGD PMID:21034455 RGD:6903271 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901 		JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member ISO GAD PMID:15118671 RGD:1331525 NCBI chr20:3,979,302...3,989,669
Ensembl chr20:3,979,035...3,989,669 		JBrowse link
G Tcf21 transcription factor 21 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 PMID:22751097 NCBI chr 1:23,906,717...23,909,576
Ensembl chr 1:23,906,717...23,909,566 		JBrowse link
G Tek TEK receptor tyrosine kinase ISO protein:increased expression:plasma RGD PMID:12814387 RGD:1601489 NCBI chr 5:113,725,717...113,852,799
Ensembl chr 5:113,725,717...113,852,799 		JBrowse link
G Tert telomerase reverse transcriptase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16890917 NCBI chr 1:32,250,876...32,275,330
Ensembl chr 1:32,251,714...32,272,476 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO GAD PMID:15118671 RGD:1331525 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199 		JBrowse link
G Thbd thrombomodulin severity ISO RGD PMID:17012137 RGD:1601638 NCBI chr 3:142,748,673...142,752,325
Ensembl chr 3:142,748,674...142,752,325 		JBrowse link
G Tlr4 toll-like receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20524934, PMID:15632890 RGD:1580736 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052 		JBrowse link
G Tnf tumor necrosis factor ISO RGD PMID:15059615 RGD:1626412 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B ISO protein:increased expression:serum RGD PMID:15926884 RGD:1620893 NCBI chr 7:93,798,580...93,826,586
Ensembl chr 7:93,798,545...93,826,665 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A severity ISO RGD PMID:19845893 RGD:5131425 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633 		JBrowse link
G Tnni3 troponin I3, cardiac type ISO RGD PMID:12221049 RGD:1580780 NCBI chr 1:72,882,806...72,886,490
Ensembl chr 1:72,882,806...72,886,488 		JBrowse link
G Tp53 tumor protein p53 ISO DNA:misssense mutation: :p.R72P (rs1042522) (human) RGD PMID:29482350 RGD:14995930 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449 		JBrowse link
G Traf6 TNF receptor associated factor 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20524934 NCBI chr 3:91,252,829...91,271,607
Ensembl chr 3:91,252,829...91,271,607 		JBrowse link
G Trib1 tribbles pseudokinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24097064 NCBI chr 7:99,954,492...99,961,026
Ensembl chr 7:99,954,492...99,961,026 		JBrowse link
G Ttn titin ISO RGD PMID:12221049 RGD:1580780 NCBI chr 3:63,565,160...63,837,815 JBrowse link
G Vdr vitamin D receptor severity ISO DNA:SNP (human) RGD PMID:9761785 RGD:4889864 NCBI chr 7:139,344,452...139,394,138
Ensembl chr 7:139,342,063...139,394,166 		JBrowse link
G Vegfa vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:14668888 PMID:15937083, PMID:15754021 RGD:1580569 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681 		JBrowse link
G Vim vimentin ISO protein:increased expression:monocyte RGD PMID:21938407 RGD:6480617 NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212 		JBrowse link
G Vtn vitronectin ISO RGD PMID:15678274 RGD:1580816 NCBI chr10:65,767,960...65,771,040
Ensembl chr10:65,767,053...65,771,038 		JBrowse link
G Wdr12 WD repeat domain 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr 9:66,851,499...66,878,534
Ensembl chr 9:66,851,940...66,877,972 		JBrowse link
G Wrn WRN RecQ like helicase ISO RGD PMID:11186893 RGD:1580824 NCBI chr16:62,483,773...62,619,018
Ensembl chr16:62,483,761...62,615,375 		JBrowse link
G Zc3hc1 zinc finger, C3HC-type containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr 4:57,684,678...57,706,613
Ensembl chr 4:57,684,678...57,706,613 		JBrowse link
Coronary Artery Disease, Autosomal Dominant 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mef2a myocyte enhancer factor 2a ISO ClinVar Annotator: match by term: Coronary artery disease/myocardial infarction
ClinVar Annotator: match by OMIM:608320		 OMIM
ClinVar		 PMID:14645853 PMID:15496429 PMID:15841183 NCBI chr 1:128,207,715...128,341,681
Ensembl chr 1:128,209,971...128,341,263 		JBrowse link
Coronary Artery Disease, Autosomal Dominant 2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrp6 LDL receptor related protein 6 ISO ClinVar Annotator: match by term: Coronary artery disease, autosomal dominant 2
ClinVar Annotator: match by OMIM:610947		 OMIM
ClinVar		 PMID:17332414 PMID:23703864 PMID:25741868 NCBI chr 4:168,194,054...168,323,962
Ensembl chr 4:168,194,927...168,323,751 		JBrowse link
Coronary Artery Disease, Development of, in HIV term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl2 C-C motif chemokine ligand 2 ISO ClinVar Annotator: match by null ClinVar PMID:11500196 PMID:15466648 PMID:16352737 PMID:16596675 PMID:18940815 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870 		JBrowse link
coronary artery vasospasm term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgap9 Rho GTPase activating protein 9 ISO ClinVar Annotator: match by term: Coronary artery spasm 3, susceptibility to
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD		 PMID:19911011 NCBI chr 7:70,612,650...70,620,900
Ensembl chr 7:70,612,103...70,620,890 		JBrowse link
G Nos3 nitric oxide synthase 3 ISO ClinVar Annotator: match by term: Coronary artery spasm 1, susceptibility to
CTD Direct Evidence: marker/mechanism		 OMIM
ClinVar
CTD		 PMID:9737779 PMID:9894802 PMID:10359729 PMID:10475066 PMID:10510054 PMID:10514107 PMID:11026457 PMID:11354626 PMID:11394896 PMID:11745998 PMID:15007011 PMID:16059745 PMID:16813604 PMID:17165044 PMID:24033266 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410 		JBrowse link
G Pon1 paraoxonase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11810302 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372 		JBrowse link
coronary restenosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme ISO CTD Direct Evidence: marker/mechanism CTD PMID:9236417 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO CTD Direct Evidence: therapeutic CTD PMID:12138120 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488 		JBrowse link
G Bche butyrylcholinesterase susceptibility ISO DNA:polymorphism: :p.A539T (human) RGD PMID:17275003 RGD:2306778 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395 		JBrowse link
G Cdh13 cadherin 13 IEP protein:increased expression:artery, smooth muscle cell RGD PMID:12376824 RGD:2293553 NCBI chr19:50,848,793...51,971,618
Ensembl chr19:50,848,736...51,972,103 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 ISO protein:increased expression:plasma RGD PMID:14578618 RGD:1598500 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930 		JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 ISO RGD PMID:14578618 RGD:1598500 NCBI chr  X:71,614,346...71,616,997
Ensembl chr  X:71,614,346...71,616,997 		JBrowse link
G F2r coagulation factor II (thrombin) receptor ISO RGD PMID:14529396 RGD:1581036 NCBI chr 2:26,118,760...26,135,340
Ensembl chr 2:26,118,760...26,135,340 		JBrowse link
G Hmox1 heme oxygenase 1 susceptibility ISO RGD PMID:16020495, PMID:14529548 RGD:1598402, RGD:1580472 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456 		JBrowse link
G Itgb2 integrin subunit beta 2 ISO RGD PMID:11703955 RGD:1581185 NCBI chr20:11,777,773...11,815,647
Ensembl chr20:11,777,783...11,815,647 		JBrowse link
G Lox lysyl oxidase IDA RGD PMID:15218472 RGD:1581881 NCBI chr18:47,500,320...47,577,819
Ensembl chr18:47,500,330...47,577,819 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 IDA RGD PMID:15583728 RGD:1582284 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254 		JBrowse link
G Mbl2 mannose binding lectin 2 susceptibility ISO DNA:polymorphisms:5' utr, exon:multiple (human) RGD PMID:15790942 RGD:1582150 NCBI chr 1:248,435,069...248,442,669
Ensembl chr 1:248,723,397...248,729,962 		JBrowse link
G Mmp3 matrix metallopeptidase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8662692 NCBI chr 8:5,676,608...5,698,579
Ensembl chr 8:5,676,665...5,698,579 		JBrowse link
G Mmp7 matrix metallopeptidase 7 treatment IEP RGD PMID:21139058 RGD:9685362 NCBI chr 8:5,893,253...5,900,965
Ensembl chr 8:5,893,249...5,901,049 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16489563 NCBI chr 5:164,844,642...164,864,360
Ensembl chr 5:164,845,925...164,860,910 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor treatment IDA RGD PMID:7955204 RGD:10059621 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240 		JBrowse link
G Npy5r neuropeptide Y receptor Y5 IEP mRNA, protein:increased expression:carotid artery RGD PMID:12689918 RGD:1625501 NCBI chr16:24,796,685...24,805,730
Ensembl chr16:24,797,124...24,805,079 		JBrowse link
G Spp1 secreted phosphoprotein 1 ISO RGD PMID:12114325, PMID:16373617 RGD:1581358, RGD:1581366 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901 		JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:16319143, PMID:16319143 RGD:1580322 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
G Tp53 tumor protein p53 ISO RGD PMID:14740296 RGD:1580742 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449 		JBrowse link
G Ucp3 uncoupling protein 3 susceptibility ISO DNA:polymorphism:promoter:-55C>T (human) RGD PMID:17786284 RGD:2313513 NCBI chr 1:165,482,912...165,495,895
Ensembl chr 1:165,482,155...165,496,206 		JBrowse link
coronary stenosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apln apelin ISO protein:decreased expression:plasma RGD PMID:19015606 RGD:2313942 NCBI chr  X:134,856,719...134,866,210
Ensembl chr  X:134,856,726...134,866,210 		JBrowse link
G Edn1 endothelin 1 treatment ISO RGD PMID:10854676 RGD:8661796 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324 		JBrowse link
G Hrh2 histamine receptor H 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12721106 NCBI chr17:10,912,959...10,931,389
Ensembl chr17:10,921,507...10,952,441 		JBrowse link
G Igf1 insulin-like growth factor 1 IEP mRNA:increased expression:myocyte: RGD PMID:8102103 RGD:10046053 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor IEP mRNA:increased expression:myocyte: RGD PMID:8102103 RGD:10046053 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516 		JBrowse link
G Itgav integrin subunit alpha V IDA RGD PMID:11922905 RGD:1582454 NCBI chr 3:71,113,269...71,205,958
Ensembl chr 3:71,114,100...71,202,411 		JBrowse link
G Mdk midkine IDA RGD PMID:10683378 RGD:1299187 NCBI chr 3:80,841,003...80,843,895
Ensembl chr 3:80,841,005...80,842,916 		JBrowse link
G Myh7 myosin heavy chain 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12721106 NCBI chr15:33,605,769...33,657,761
Ensembl chr15:33,634,422...33,656,089 		JBrowse link
G Nppa natriuretic peptide A ISO CTD Direct Evidence: marker/mechanism CTD PMID:12721106 NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705 		JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 ISO DNA:missense mutations:cds:p.L125V, p.S563N (human) RGD PMID:10571959 RGD:1598382 NCBI chr10:94,850,971...94,913,202 JBrowse link
G Prkce protein kinase C, epsilon ISO CTD Direct Evidence: marker/mechanism CTD PMID:16782078 NCBI chr 6:9,483,400...9,973,396
Ensembl chr 6:9,790,422...9,973,396 		JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B ISO protein:increased expression:serum RGD PMID:15569000 RGD:1624167 NCBI chr 7:93,798,580...93,826,586
Ensembl chr 7:93,798,545...93,826,665 		JBrowse link
coronary thrombosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itgb3 integrin subunit beta 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8598867 NCBI chr10:92,667,869...92,783,413
Ensembl chr10:92,667,869...92,783,410 		JBrowse link
G Plat plasminogen activator, tissue type ISO CTD Direct Evidence: therapeutic CTD PMID:1452937 PMID:8172379 PMID:15301905 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889 		JBrowse link
Hypertension Resistant to Conventional Therapy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gstm1 glutathione S-transferase mu 1 susceptibility ISO DNA:deletion:cds: (human) RGD PMID:19279659 RGD:7495846 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306 		JBrowse link
G Nos3 nitric oxide synthase 3 ISO ClinVar Annotator: match by term: Hypertension resistant to conventional therapy ClinVar PMID:9737779 PMID:9894802 PMID:10475066 PMID:10510054 PMID:10514107 PMID:11026457 PMID:11354626 PMID:11394896 PMID:11745998 PMID:15007011 PMID:16059745 PMID:16813604 PMID:17165044 PMID:24033266 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410 		JBrowse link
intermediate coronary syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme ISO mRNA:increased expression:ventricular myocardium (human)
mRNA:increased expression:myocardium		 RGD PMID:15131005, PMID:11451295 RGD:8142363, RGD:8548894 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822 		JBrowse link
G Agt angiotensinogen ISO mRNA:increased expression:myocardium RGD PMID:11451295 RGD:8548894 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a ISO mRNA:increased expression:myocardium RGD PMID:11451295 RGD:8548894 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO protein:increased serine phosphorylation:platelet RGD PMID:20467748 RGD:5509094 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258 		JBrowse link
G Apoa4 apolipoprotein A4 ISO protein:decreased expression:blood plasma (human) RGD PMID:20367977 RGD:5685646 NCBI chr 8:50,536,983...50,539,371
Ensembl chr 8:50,537,009...50,539,376 		JBrowse link
G Bdnf brain-derived neurotrophic factor ISO RGD PMID:16186425 RGD:4891111 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210 		JBrowse link
G Crp C-reactive protein disease_progression ISO RGD PMID:9761079 RGD:9491780 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713 		JBrowse link
G Edn1 endothelin 1 ISO associated with Coronary Artery Disease;protein:increased expression:coronary sinus, plasma (human) RGD PMID:14556009 RGD:8661755 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324 		JBrowse link
G F7 coagulation factor VII ISO protein:increased expression:plasma (human) RGD PMID:10653827 RGD:2312399 NCBI chr16:81,824,610...81,834,923
Ensembl chr16:81,824,111...81,834,945 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase ISO RGD PMID:18333374 RGD:5508458 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654 		JBrowse link
G Itga2 integrin subunit alpha 2 susceptibility ISO RGD PMID:15104219 RGD:1582303 NCBI chr 2:46,996,904...47,097,011
Ensembl chr 2:47,000,323...47,096,961 		JBrowse link
G Itih4 inter-alpha-trypsin inhibitor heavy chain 4 ISO RGD PMID:10486281 RGD:1582334 NCBI chr16:6,970,367...6,985,538
Ensembl chr16:6,970,342...6,985,579 		JBrowse link
G Mmp1 matrix metallopeptidase 1 ISO RGD PMID:14675588 RGD:1582536 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591 		JBrowse link
G Pappa1 pappalysin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11586954 NCBI chr 5:80,919,932...81,153,904
Ensembl chr 5:80,920,568...81,150,940 		JBrowse link
G Plau plasminogen activator, urokinase ISO CTD Direct Evidence: therapeutic CTD PMID:2382605 NCBI chr15:3,644,296...3,650,765
Ensembl chr15:3,644,769...3,650,819 		JBrowse link
G Selp selectin P ISO protein:increased expression:serum RGD PMID:21162967 RGD:6219003 NCBI chr13:82,428,914...82,464,629
Ensembl chr13:82,429,063...82,464,628 		JBrowse link
G Serpinc1 serpin family C member 1 treatment ISO RGD PMID:8122184 RGD:11035255 NCBI chr13:78,806,107...78,820,375
Ensembl chr13:78,805,347...78,833,192 		JBrowse link
G Sod3 superoxide dismutase 3 ISO RGD PMID:14592844 RGD:1580841 NCBI chr14:60,958,583...60,971,143
Ensembl chr14:60,958,592...60,964,324 		JBrowse link
G Txn1 thioredoxin 1 ISO RGD PMID:15749180 RGD:1580784 NCBI chr 5:75,049,735...75,057,731
Ensembl chr 5:75,049,747...75,057,752 		JBrowse link
intermittent claudication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bad BCL2-associated agonist of cell death IEP RGD PMID:23658678 RGD:9586024 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 IEP RGD PMID:23658678 RGD:9586024 NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator IEP RGD PMID:23658678 RGD:9586024 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207 		JBrowse link
G Bbc3 Bcl-2 binding component 3 IEP RGD PMID:23658678 RGD:9586024 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Casp3 caspase 3 IDA RGD PMID:23658678 RGD:9586024 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204 		JBrowse link
G Eif3e eukaryotic translation initiation factor 3 subunit E treatment IMP RGD PMID:21771896 RGD:10395378 NCBI chr 7:82,997,694...83,037,231 JBrowse link
G Epas1 endothelial PAS domain protein 1 treatment IDA RGD PMID:21771896 RGD:10395378 NCBI chr 6:10,306,508...10,385,239
Ensembl chr 6:10,306,405...10,387,265 		JBrowse link
G Mdm2 MDM2 proto-oncogene treatment IEP RGD PMID:23658678 RGD:9586024 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328 		JBrowse link
G Sirt2 sirtuin 2 IEP associated with Spinal Stenosis;protein:decreased expression:dorsal horn of spinal cord, ventral horn of spinal cord RGD PMID:23658678 RGD:9586024 NCBI chr 1:86,948,866...86,971,954
Ensembl chr 1:86,948,918...86,971,952 		JBrowse link
Medial Coronary Sclerosis of Infancy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 ISO ClinVar Annotator: match by term: Coronary sclerosis, medial, of infancy ClinVar PMID:15940697 PMID:25741868 NCBI chr 1:21,748,201...21,813,205
Ensembl chr 1:21,748,261...21,813,371 		JBrowse link
mesenteric vascular occlusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Icam1 intercellular adhesion molecule 1 treatment IMP RGD PMID:7858885 RGD:11522711 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059 		JBrowse link
G Jak2 Janus kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20434300 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509 		JBrowse link
G Serpind1 serpin family D member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:1831893 NCBI chr11:87,913,814...87,924,880
Ensembl chr11:87,913,806...87,924,816 		JBrowse link
Moyamoya disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle ISO
ISS		 ClinVar Annotator: match by term: Moyamoya disease
OMIM:252350 | OMIM:300845 | OMIM:607151 | OMIM:608796 | OMIM:614042 | OMIM:615750		 ClinVar
MouseDO		 PMID:25741868 PMID:28492532 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394 		JBrowse link
G Fas Fas cell surface death receptor ISO ClinVar Annotator: match by term: Moyamoya disease ClinVar NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790 		JBrowse link
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 ISS OMIM:252350 | OMIM:300845 | OMIM:607151 | OMIM:608796 | OMIM:614042 | OMIM:615750 MouseDO NCBI chr 2:181,045,694...181,103,321
Ensembl chr 2:181,045,703...181,102,918 		JBrowse link
G Rnf213 ring finger protein 213 ISS OMIM:252350 | OMIM:300845 | OMIM:607151 | OMIM:608796 | OMIM:614042 | OMIM:615750 MouseDO NCBI chr10:108,527,351...108,626,372
Ensembl chr10:108,527,740...108,624,688 		JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 ISO RGD PMID:16723886 RGD:1580650 NCBI chr10:107,338,465...107,386,072
Ensembl chr10:107,338,465...107,386,072 		JBrowse link
Moyamoya Disease 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 ISO ClinVar Annotator: match by term: Moyamoya disease 1 ClinVar PMID:26777256 NCBI chr 2:181,045,694...181,103,321
Ensembl chr 2:181,045,703...181,102,918 		JBrowse link
Moyamoya Disease 2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rnf213 ring finger protein 213 susceptibility ISO ClinVar Annotator: match by OMIM:607151
ClinVar Annotator: match by term: Moyamoya disease 2
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
OMIM		 PMID:21048783 PMID:21799892 PMID:22377813 PMID:22931863 PMID:25278557 PMID:25741868 PMID:28492532 PMID:31474762 NCBI chr10:108,527,351...108,626,372
Ensembl chr10:108,527,740...108,624,688 		JBrowse link
Moyamoya Disease 4 with Short Stature, Hypergonadotropic Hypogonadism, and Facial Dysmorphism term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcap31 B-cell receptor-associated protein 31 ISO ClinVar Annotator: match by term: Chromosome Xq28 deletion syndrome ClinVar PMID:24011989 PMID:25741868 NCBI chr  X:157,094,365...157,126,397
Ensembl chr  X:157,095,937...157,126,393 		JBrowse link
G Slc6a8 solute carrier family 6 member 8 ISO ClinVar Annotator: match by term: Chromosome Xq28 deletion syndrome ClinVar PMID:24011989 NCBI chr  X:157,129,987...157,139,321
Ensembl chr  X:157,129,987...157,139,291 		JBrowse link
Moyamoya Disease 5 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle ISO ClinVar Annotator: match by term: Moyamoya disease 5 OMIM
ClinVar		 PMID:10532176 PMID:13129918 PMID:14730227 PMID:15138499 PMID:15472996 PMID:17994018 PMID:19409525 PMID:20734336 PMID:20970362 PMID:22302747 PMID:22543189 PMID:22752479 PMID:22790431 PMID:22831780 PMID:22946110 PMID:23253043 PMID:23613326 PMID:24033266 PMID:24293535 PMID:24621862 PMID:24998021 PMID:25326635 PMID:25644172 PMID:25741868 PMID:25759435 PMID:25944730 PMID:26034244 PMID:26153420 PMID:26637293 PMID:27176728 PMID:27481187 PMID:27549731 PMID:27551047 PMID:28492532 PMID:28652363 PMID:29300374 PMID:30341550 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394 		JBrowse link
Moyamoya Disease 6 with Achalasia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 ISO ClinVar Annotator: match by term: Moyamoya disease 6 with achalasia ClinVar
OMIM		 PMID:24581742 PMID:25741868 PMID:26777256 NCBI chr 2:181,045,694...181,103,321
Ensembl chr 2:181,045,703...181,102,918 		JBrowse link
Multi-Infarct Dementia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein ISO protein:decreased expression:cerebrospinal fluid: RGD PMID:1677459 RGD:10054257 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator treatment IEP RGD PMID:18938189 RGD:10054050 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207 		JBrowse link
G Bcl2 BCL2, apoptosis regulator treatment IEP RGD PMID:18938189 RGD:10054050 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase treatment IEP RGD PMID:21279683 RGD:10449132 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926 		JBrowse link
G Il2 interleukin 2 severity ISO protein:increased secretion:mononuclear cell: RGD PMID:8586980 RGD:10047081 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854 		JBrowse link
myocardial infarction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc9 ATP binding cassette subfamily C member 9 ISO ClinVar Annotator: match by term: Myocardial infarction, susceptibility to ClinVar PMID:16563363 PMID:23861362 PMID:24033266 PMID:25741868 PMID:28492532 NCBI chr 4:176,806,098...176,928,540
Ensembl chr 4:176,805,431...176,922,424 		JBrowse link
G Ace angiotensin I converting enzyme treatment
susceptibility		 ISO
IEP
IMP		 ClinVar Annotator: match by term: Heart attack
CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Type 1;DNA:deletion:intron:IVS16+1464-1751del (human)
associated with Myocardial Reperfusion Injury		 ClinVar
CTD		 PMID:1313972 PMID:1319114 PMID:1328889 PMID:1386652 PMID:1976655 PMID:2847529 PMID:2849100 PMID:7593601 PMID:7729604 PMID:7854377 PMID:7909524 PMID:8131299 PMID:8131300 PMID:8136829 PMID:8170965 PMID:8208911 PMID:8298638 PMID:8314010 PMID:8541160 PMID:8644984 PMID:8675669 PMID:9120002 PMID:9236417 PMID:9259580 PMID:9699903 PMID:9737775 PMID:9916793 PMID:10099885 PMID:10636736 PMID:10643899 PMID:10841123 PMID:11687636 PMID:11956052 PMID:12220450 PMID:12666117 PMID:14657821 PMID:14872014 PMID:15110771 PMID:15277638 PMID:15381116 PMID:15531537 PMID:15534175 PMID:15635071 PMID:19221299, PMID:15118671, PMID:23959549, PMID:15671045, PMID:7555560, PMID:21975128 RGD:1331525, RGD:9685449, RGD:1558664, RGD:7829785, RGD:6893480 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822 		JBrowse link
G Ace2 angiotensin I converting enzyme 2 treatment IEP
IDA		 mRNA:increased expression:myocardium RGD PMID:15671045, PMID:23959549 RGD:1558664, RGD:9685449 NCBI chr  X:32,050,734...32,095,860
Ensembl chr  X:32,049,931...32,096,016 		JBrowse link
G Acta2 actin alpha 2, smooth muscle ISO CTD Direct Evidence: marker/mechanism CTD PMID:24358288 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394 		JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 IEP RGD PMID:15625312 RGD:9681751 NCBI chr11:25,342,119...25,350,938
Ensembl chr11:25,342,126...25,350,974 		JBrowse link
G Add1 adducin 1 no_association ISO DNA:missense mutation:cds:p.G460W (human) RGD PMID:17082469, PMID:16420563 RGD:5147995, RGD:5148001 NCBI chr14:81,367,466...81,426,610
Ensembl chr14:81,367,468...81,426,496 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing disease_progression IEP RGD PMID:21326342 RGD:5686351 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488 		JBrowse link
G Adipor1 adiponectin receptor 1 ISO mRNA, protein:decreased expression:heart left ventricle RGD PMID:16415076 RGD:1625764 NCBI chr13:51,240,470...51,260,233
Ensembl chr13:51,240,911...51,260,228 		JBrowse link
G Adipor2 adiponectin receptor 2 ISO mRNA, protein:decreased expression:heart left ventricle RGD PMID:16415076 RGD:1625764 NCBI chr 4:151,412,135...151,480,108
Ensembl chr 4:151,414,684...151,428,894 		JBrowse link
G Adora1 adenosine A1 receptor ISO CTD Direct Evidence: therapeutic CTD PMID:12160945 NCBI chr13:51,042,111...51,076,913
Ensembl chr13:51,042,248...51,076,852 		JBrowse link
G Adora3 adenosine A3 receptor ISO CTD Direct Evidence: therapeutic CTD PMID:12160945 PMID:20132822 NCBI chr 2:208,336,909...208,379,217
Ensembl chr 2:208,373,154...208,376,803 		JBrowse link
G Adra2b adrenoceptor alpha 2B ISO RGD PMID:12535806 RGD:1559314 NCBI chr 3:119,805,941...119,809,987
Ensembl chr 3:119,805,941...119,809,987 		JBrowse link
G Adrb1 adrenoceptor beta 1 ISO
IMP		 GAD
RGD		 PMID:15118671, PMID:17143192 RGD:1331525, RGD:7241557 NCBI chr 1:277,537,585...277,538,985
Ensembl chr 1:277,537,585...277,538,985 		JBrowse link
G Adrb2 adrenoceptor beta 2 susceptibility ISO
IEP		 DNA:polymorphisms: :p.G16R, p.Q27E, p.T164I
mRNA:decreased expression:heart		 RGD PMID:15520258, PMID:12400771 RGD:1601126, RGD:8548519 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834 		JBrowse link
G Ager advanced glycosylation end product-specific receptor susceptibility IEP
ISO		 mRNA:increased expression:left ventricle myocardium (rat)
DNA:polymorphism:promoter:-429T>C (human)		 RGD PMID:19910580, PMID:16728681 RGD:2325647, RGD:1625333 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079 		JBrowse link
G Agt angiotensinogen susceptibility IDA
ISO		 CTD Direct Evidence: marker/mechanism
associated with Coronary Artery Disease;DNA:polymorphism: :p.M235T (human)
associated with hypertension;DNA:polymorphism: :p.M235T		 CTD PMID:1668233 PMID:16413583, PMID:21167013, PMID:15118671, PMID:11393670, PMID:17299437 RGD:5129191, RGD:1331525, RGD:1566452, RGD:1601132 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a susceptibility
no_association		 ISO
IEP		 DNA:polymorphism:3' utr:1166A>C
DNA:polymorphism:3' utr:1166A>C (human)		 RGD
GAD		 PMID:16061119, PMID:9652322, PMID:15118671, PMID:9857918 RGD:1601150, RGD:10047101, RGD:1331525, RGD:1566499 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077 		JBrowse link
G Ahsg alpha-2-HS-glycoprotein ISO protein:increased expression:plasma RGD PMID:19029462 RGD:2313810 NCBI chr11:81,711,269...81,717,594 JBrowse link
G Aimp1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 IEP RGD PMID:14732363 RGD:1580021 NCBI chr 2:237,727,782...237,751,327
Ensembl chr 2:237,727,764...237,751,378 		JBrowse link
G Ak1 adenylate kinase 1 treatment IEP RGD PMID:22229508 RGD:11100025 NCBI chr 3:11,652,143...11,659,135 JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO
IDA		 protein:increased serine phosphorylation:platelet
protein:decreased serine phosphorylation:heart		 RGD PMID:20467748, PMID:20352476 RGD:5509094, RGD:10041035 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member ISO DNA:missense mutation: :p.E487K (human) RGD PMID:12452318 RGD:2311152 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752 		JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein no_association ISO DNA:snps:multiple (human) RGD
GAD		 PMID:14770184, PMID:15118671, PMID:19046748 RGD:1578317, RGD:1331525, RGD:2313891 NCBI chr12:6,854,930...6,879,112
Ensembl chr12:6,854,920...6,879,154 		JBrowse link
G Ang angiogenin ISO RGD PMID:18462761 RGD:2325719 NCBI chr15:28,022,926...28,028,636 JBrowse link
G Angpt1 angiopoietin 1 IEP mRNA, protein:decreased expression:myocardium RGD PMID:15364619 RGD:1626168 NCBI chr 7:81,338,327...81,592,459
Ensembl chr 7:81,342,280...81,592,206 		JBrowse link
G Angpt2 angiopoietin 2 IEP protein:increased expression:left ventricular wall, heart septum (rat) RGD PMID:16714360 RGD:1601493 NCBI chr16:75,966,480...76,016,147
Ensembl chr16:75,966,352...76,016,195 		JBrowse link
G Anxa5 annexin A5 susceptibility
no_association		 ISO
IEP		 DNA:polymorphism: :-1C>T (human)
protein:altered localization:cardiac muscle cell, sarcolemma
protein:increased expression:plasma		 RGD PMID:12200370, PMID:16501019, PMID:8814351, PMID:16025836 RGD:2317542, RGD:2317541, RGD:2317543, RGD:1578384 NCBI chr 2:123,162,477...123,194,730
Ensembl chr 2:123,162,461...123,193,130 		JBrowse link
G Apoa1 apolipoprotein A1 no_association ISO DNA:polymorphisms RGD
GAD		 PMID:20176799, PMID:15118671, PMID:10428310 RGD:2325759, RGD:1331525, RGD:1578442 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875 		JBrowse link
G Apoa4 apolipoprotein A4 no_association
susceptibility		 ISO DNA:mutation:intron:IVS2 (human)
associated with Diabetes Mellitus, Type 2; DNA:missense mutation:cds:p.Q360H (human)		 RGD
GAD		 PMID:10428310, PMID:7958503, PMID:15118671 RGD:1578442, RGD:5685678, RGD:1331525 NCBI chr 8:50,536,983...50,539,371
Ensembl chr 8:50,537,009...50,539,376 		JBrowse link
G Apob apolipoprotein B ISO GAD PMID:15118671 RGD:1331525 NCBI chr 6:33,176,826...33,216,381
Ensembl chr 6:33,176,778...33,224,997 		JBrowse link
G Apoc3 apolipoprotein C3 no_association ISO RGD
GAD		 PMID:10428310, PMID:15118671 RGD:1578442, RGD:1331525 NCBI chr 8:50,529,318...50,531,498
Ensembl chr 8:50,529,318...50,531,498 		JBrowse link
G Apoe apolipoprotein E susceptibility ISO DNA:missense mutations, haplotypes:cds:p.C112R, p.R158C (human)
CTD Direct Evidence: marker/mechanism
DNA:missense mutations, haplotype:cds:p.C112R, p.C158R (human)
ClinVar Annotator: match by null		 CTD
ClinVar		 PMID:10587578 PMID:12774036, PMID:17217375, PMID:10090925, PMID:15118671 RGD:1601229, RGD:10449412, RGD:1331525 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057 		JBrowse link
G Apoh apolipoprotein H ISO
IDA		 RGD PMID:15322656, PMID:12826288 RGD:2313985, RGD:10054111 NCBI chr10:96,640,013...96,653,939
Ensembl chr10:96,639,924...96,653,938 		JBrowse link
G Atg7 autophagy related 7 IEP mRNA:increased expression:plantaris RGD PMID:24427319 RGD:11557988 NCBI chr 4:146,570,113...146,777,093
Ensembl chr 4:146,598,413...146,777,124 		JBrowse link
G Atm ATM serine/threonine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:24358288, PMID:24358288 RGD:10053570 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045 		JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 ISO CTD Direct Evidence: therapeutic CTD PMID:29702141 NCBI chr 2:204,003,742...204,032,023
Ensembl chr 2:204,003,742...204,032,023 		JBrowse link
G Atp5f1d ATP synthase F1 subunit delta treatment IEP protein:decreased expression:myocardium (rat) RGD PMID:29300489, PMID:23809007 RGD:13792656, RGD:13792681 NCBI chr 7:12,426,807...12,432,120
Ensembl chr 7:12,426,809...12,432,130 		JBrowse link
G Atp5po ATP synthase peripheral stalk subunit OSCP treatment ISO RGD PMID:24692845 RGD:13801194 NCBI chr11:32,081,606...32,087,918
Ensembl chr11:32,081,574...32,088,002 		JBrowse link
G Avpr1a arginine vasopressin receptor 1A IMP RGD PMID:16423716 RGD:2300376 NCBI chr 7:67,341,366...67,345,290
Ensembl chr 7:67,341,080...67,345,308 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29122578 NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:20079142 PMID:25450231 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207 		JBrowse link
G Bcl2 BCL2, apoptosis regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:19027736 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374 		JBrowse link
G Bcl2l1 Bcl2-like 1 IMP
ISO		 CTD Direct Evidence: marker/mechanism CTD PMID:20079142, PMID:17467744 RGD:1643494 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810 		JBrowse link
G Bdkrb1 bradykinin receptor B1 IEP mRNA:increased expression:heart RGD PMID:12489796 RGD:704379 NCBI chr 6:129,437,423...129,441,553
Ensembl chr 6:129,438,158...129,440,574 		JBrowse link
G Bdkrb2 bradykinin receptor B2 IEP mRNA:increased expression:heart RGD PMID:12489796 RGD:704379 NCBI chr 6:129,399,468...129,429,676
Ensembl chr 6:129,399,468...129,429,676 		JBrowse link
G Becn1 beclin 1 treatment ISO
IEP		 CTD Direct Evidence: marker/mechanism CTD PMID:20079142, PMID:20079142 RGD:11561913 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 IEP RGD PMID:15081314 RGD:2293137 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413 		JBrowse link
G Bnip3 BCL2 interacting protein 3 IEP mRNA:increased expression:plantaris RGD PMID:24427319 RGD:11557988 NCBI chr 1:211,248,098...211,265,282
Ensembl chr 1:211,248,098...211,265,282 		JBrowse link
G Brap BRCA1 associated protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:19198608 NCBI chr12:40,381,892...40,417,764
Ensembl chr12:40,383,577...40,417,654 		JBrowse link
G Brinp3 BMP/retinoic acid inducible neural specific 3 susceptibility ISO DNA:SNPs:3' end: RGD PMID:18430236 RGD:14398488 NCBI chr13:63,526,486...63,959,390
Ensembl chr13:63,526,486...63,959,332 		JBrowse link
G C3 complement C3 IEP mRNA, protein:increased expression:myocardium RGD PMID:16996480 RGD:1600605 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167 		JBrowse link
G C7 c