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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Eye Injuries
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Accession:DOID:9006447 term browser browse the term
Definition:Damage or trauma inflicted to the eye by external means. The concept includes both surface injuries and intraocular injuries.
Synonyms:exact_synonym: Eye Injury
 primary_id: MESH:D005131;   RDO:0005555
 xref: EFO:0009485



show annotations for term's descendants           Sort by:
Eye Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf2 fibroblast growth factor 2 ISO
IEP
protein:increased expression:lens RGD PMID:15273655 PMID:15273655 RGD:8655664, RGD:8655664 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
JBrowse link
G Mir183 microRNA 183 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27208084 NCBI chr 4:58,788,614...58,788,723
Ensembl chr 4:58,788,614...58,788,723
JBrowse link
G Mir96 microRNA 96 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27208084 NCBI chr 4:58,788,411...58,788,516
Ensembl chr 4:58,788,411...58,788,516
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma treatment ISO RGD PMID:18658087 RGD:8552893 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
Corneal Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28038895 NCBI chr10:45,892,993...45,902,680
Ensembl chr10:45,892,924...45,902,681
JBrowse link
G Tp63 tumor protein p63 ISO RGD PMID:12167247 RGD:11568649 NCBI chr11:74,838,858...75,049,764
Ensembl chr11:74,838,859...75,049,398
JBrowse link
Corneal Perforation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma ISO mRNA,protein:increased expression:corneal RGD PMID:15832292 RGD:8157597 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
Eye Burns term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il10 interleukin 10 treatment IDA RGD PMID:22553604 RGD:7364851 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il1b interleukin 1 beta ISO protein:increased expression:retina RGD PMID:9618720 RGD:7794723 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma IEP protein:increased expression:cornea, neutrophil, macrophage (rat) RGD PMID:24194635 RGD:8552904 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
Penetrating Eye Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf2 fibroblast growth factor 2 ISO mRNA:increased expression:retina RGD PMID:9268592 RGD:8655567 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
JBrowse link
G Neo1 neogenin 1 IEP protein:increased expression:retina RGD PMID:21887516 RGD:9850142 NCBI chr 8:59,273,860...59,426,486
Ensembl chr 8:59,275,569...59,430,348
JBrowse link
G Rgma repulsive guidance molecule BMP co-receptor a IEP protein:increased expression:retina RGD PMID:21887516 RGD:9850142 NCBI chr 1:127,128,934...127,172,918
Ensembl chr 1:127,128,934...127,172,918
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 21128
    sensory system disease 6939
      eye disease 3475
        Eye Injuries 11
          Anterior Capsular Rupture, Ocular 0
          Corneal Injuries + 3
          Eye Burns 3
          Eye Foreign Bodies 0
          Penetrating Eye Injuries 3
          Posterior Capsular Rupture, Ocular 0
Path 2
Term Annotations click to browse term
  disease 21128
    disease of anatomical entity 18212
      nervous system disease 14060
        Neurologic Manifestations 10040
          sensory system disease 6939
            eye disease 3475
              Eye Injuries 11
                Anterior Capsular Rupture, Ocular 0
                Corneal Injuries + 3
                Eye Burns 3
                Eye Foreign Bodies 0
                Penetrating Eye Injuries 3
                Posterior Capsular Rupture, Ocular 0
paths to the root