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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Feminization
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Accession:DOID:9006421 term browser browse the term
Definition:Development of female secondary SEX CHARACTERISTICS in the MALE. It is due to the effects of estrogenic metabolites of precursors from endogenous or exogenous sources, such as ADRENAL GLANDS or therapeutic drugs.
Synonyms:exact_synonym: Feminizations
 primary_id: MESH:D005262
For additional species annotation, visit the Alliance of Genome Resources.



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Feminization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr1 estrogen receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22275727 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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  disease 18215
    Pathological Conditions, Signs and Symptoms 11356
      Signs and Symptoms 7293
        Feminization 1
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