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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Spinal Cord Vascular Diseases
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Accession:DOID:9006308 term browser browse the term
Definition:Pathological processes involving any of the BLOOD VESSELS feeding the SPINAL CORD, such as the anterior and paired posterior spinal arteries or their many branches. Disease processes may include ATHEROSCLEROSIS; EMBOLISM; and ARTERIOVENOUS MALFORMATIONS leading to ISCHEMIA or HEMORRHAGE into the spinal cord (hematomyelia).
Synonyms:exact_synonym: Hematomyelia;   Hematomyelias;   Posterior Spinal Artery Syndrome
 primary_id: MESH:D020758;   RDO:0007424
For additional species annotation, visit the Alliance of Genome Resources.



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Spinal Cord Ischemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btg2 BTG anti-proliferation factor 2 IEP RGD PMID:14697320 RGD:2289074 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15696051 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
Spinal Cord Reperfusion Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bad BCL2-associated agonist of cell death treatment IDA RGD PMID:23643992 RGD:10053660 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bdnf brain-derived neurotrophic factor treatment IEP RGD PMID:24361987 RGD:10059358 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Becn1 beclin 1 treatment IEP RGD PMID:25374587 RGD:11561952 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Cdk5 cyclin-dependent kinase 5 treatment IDA RGD PMID:25301568 RGD:13782374 NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112
JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 treatment IEP RGD PMID:25301568 RGD:13782374 NCBI chr10:65,484,266...65,485,467
Ensembl chr10:65,483,941...65,488,456
JBrowse link
G Creb1 cAMP responsive element binding protein 1 treatment IEP RGD PMID:17368520 PMID:29310813 RGD:155226865, RGD:155226868 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 IMP RGD PMID:27760212 RGD:12910551 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 IMP RGD PMID:27760212 RGD:12910551 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase treatment IEP RGD PMID:30195603 RGD:13792615 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 treatment IEP protein:increased expression:spinal cord: RGD PMID:24463125 RGD:11354961 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa treatment ISO RGD PMID:10903607 RGD:11100044 NCBI chr18:23,764,367...23,774,816
Ensembl chr18:23,764,368...23,775,133
JBrowse link
G Siah1 siah E3 ubiquitin protein ligase 1 treatment IEP RGD PMID:30195603 RGD:13792615 NCBI chr19:20,378,908...20,402,512
Ensembl chr19:20,378,439...20,403,808
JBrowse link
G Tlr4 toll-like receptor 4 IMP RGD PMID:27760212 RGD:12910551 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 18215
    disease of anatomical entity 17576
      cardiovascular system disease 4877
        vascular disease 3660
          Spinal Cord Vascular Diseases 15
            Spinal Cord Ischemia + 15
Path 2
Term Annotations click to browse term
  disease 18215
    disease of anatomical entity 17576
      nervous system disease 13207
        central nervous system disease 11364
          spinal cord disease 1674
            Spinal Cord Vascular Diseases 15
              Spinal Cord Ischemia + 15
paths to the root