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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Experimental Pancreatitis
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Accession:DOID:9006263 term browser browse the term
Definition:Inflammation of the pancreas induced experimentally in laboratory animals.
For additional species annotation, visit the Alliance of Genome Resources.



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Experimental Pancreatitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Elane elastase, neutrophil expressed treatment IMP RGD PMID:18486906 RGD:10450567 NCBI chr 7:9,817,251...9,819,174
Ensembl chr 7:9,817,252...9,819,100
JBrowse link
G Fgf21 fibroblast growth factor 21 treatment ISO RGD PMID:19664632 PMID:19664632 RGD:10401870, RGD:10401870 NCBI chr 1:96,083,495...96,084,738
Ensembl chr 1:96,083,441...96,090,454
JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma treatment IDA RGD PMID:19195057 RGD:12791282 NCBI chr  X:152,216,485...152,241,476
Ensembl chr  X:152,216,596...152,239,499
JBrowse link
G Reg3b regenerating family member 3 beta IEP protein:increased expression:pancreatic juice (rat) RGD PMID:7809015 RGD:9999210 NCBI chr 4:110,861,775...110,865,015
Ensembl chr 4:110,861,775...110,865,015
JBrowse link
G Tbxa2r thromboxane A2 receptor treatment IMP RGD PMID:11341608 RGD:11059600 NCBI chr 7:8,383,347...8,390,753
Ensembl chr 7:8,383,378...8,388,176
JBrowse link
Acute Experimental Pancreatitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 treatment IEP RGD PMID:18416460 RGD:13782074 NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101
JBrowse link
G Bcl2l1 Bcl2-like 1 IEP protein:increased expression:pancreas, mitochondrion (rat) RGD PMID:19331832 RGD:11353791 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Becn1 beclin 1 treatment ISO RGD PMID:22850625 RGD:11560530 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A IEP RGD PMID:10451498 RGD:10043817 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Ednra endothelin receptor type A treatment IMP RGD PMID:12799311 RGD:1581841 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049
JBrowse link
G Fas Fas cell surface death receptor severity ISO protein:increased expression:Kupffer cell: RGD PMID:15797225 PMID:15797225 RGD:14700708, RGD:14700708 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Faslg Fas ligand severity ISO protein:increased expression:Kupffer cell: RGD PMID:15797225 PMID:15797225 RGD:14700708, RGD:14700708 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Gss glutathione synthetase IEP RGD PMID:17897920 RGD:11353819 NCBI chr 3:144,047,849...144,078,197
Ensembl chr 3:144,047,850...144,078,198
JBrowse link
G Hmgb1 high mobility group box 1 treatment IMP RGD PMID:23706497 RGD:10402063 NCBI chr12:5,973,062...5,978,565
Ensembl chr12:5,901,586...5,978,565
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 IEP protein:increased expression:neutrophil: RGD PMID:26464680 RGD:11354914 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Icam1 intercellular adhesion molecule 1 treatment IEP
IMP
RGD PMID:23706497 PMID:10201790 RGD:10402063, RGD:11520782 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Il10 interleukin 10 treatment IEP RGD PMID:25323753 RGD:11049477 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il4 interleukin 4 treatment IEP RGD PMID:24876883 RGD:10402805 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Jak1 Janus kinase 1 treatment IEP RGD PMID:21369693 RGD:19165136 NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926
JBrowse link
G Kmo kynurenine 3-monooxygenase disease_progression ISO
IMP
RGD PMID:26752518 PMID:28398044 RGD:11342439, RGD:13703053 NCBI chr13:87,557,080...87,589,334
Ensembl chr13:87,557,286...87,588,881
JBrowse link
G Kras KRAS proto-oncogene, GTPase IEP RGD PMID:8913708 RGD:11062095 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 ISO protein:decreased expression:pancreas RGD PMID:22850625 RGD:11560530 NCBI chr  X:117,173,097...117,222,090
Ensembl chr  X:117,057,606...117,260,522
JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha treatment ISO RGD PMID:22850625 RGD:11560530 NCBI chr 3:143,783,024...143,784,670
Ensembl chr 3:143,783,024...143,784,670
JBrowse link
G Mir155 microRNA 155 treatment ISO RGD PMID:29937734 PMID:30497068 RGD:21403683, RGD:21408596 NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 ISO RGD PMID:16127429 RGD:11075069 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa treatment ISO RGD PMID:19680809 RGD:11100040 NCBI chr18:23,764,367...23,774,816
Ensembl chr18:23,764,368...23,775,133
JBrowse link
G Procr protein C receptor treatment IEP
IDA
protein:increased expression:blood RGD PMID:25688263 PMID:24749346 RGD:13515127, RGD:13515128 NCBI chr 3:144,254,596...144,258,863
Ensembl chr 3:144,254,380...144,258,903
JBrowse link
G Ptafr platelet-activating factor receptor treatment IDA RGD PMID:21633536 RGD:9999225 NCBI chr 5:144,765,770...144,795,057
Ensembl chr 5:144,765,976...144,795,251
JBrowse link
G Reg1a regenerating family member 1 alpha severity IEP
IMP
mRNA:increased expression:pancreas (rat) RGD PMID:1985964 PMID:19129610 RGD:729900, RGD:9850139 NCBI chr 4:110,892,451...110,895,115
Ensembl chr 4:110,892,453...110,895,570
JBrowse link
G Reg3b regenerating family member 3 beta IEP protein:increased expression:serum (rat) RGD PMID:11066135 RGD:9831384 NCBI chr 4:110,861,775...110,865,015
Ensembl chr 4:110,861,775...110,865,015
JBrowse link
G Serpinc1 serpin family C member 1 treatment ISO RGD PMID:19546838 RGD:11035262 NCBI chr13:73,257,208...73,271,476
Ensembl chr13:73,257,179...73,284,293
JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 treatment IDA RGD PMID:15765407 RGD:10043090 NCBI chr18:35,870,723...35,882,693
Ensembl chr18:35,824,550...35,882,642
JBrowse link
G Tnf tumor necrosis factor IEP associated with Anemia, Hemolytic RGD PMID:12845374 PMID:15164724 RGD:10449461, RGD:1580295 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A IEP protein:increased expression:serum RGD PMID:15164724 RGD:1580295 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B IEP protein:increased expression:serum RGD PMID:15164724 RGD:1580295 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206
JBrowse link
G Vwf von Willebrand factor IEP protein:increased expression:plasma: RGD PMID:17708840 RGD:11079229 NCBI chr 4:158,360,152...158,491,539
Ensembl chr 4:158,360,152...158,491,539
JBrowse link
Chronic Experimental Pancreatitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbs cystathionine beta synthase IEP protein:increased expression:arcuate nucleus (rat) RGD PMID:27778022 RGD:38456012 NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764
JBrowse link
G Gli1 GLI family zinc finger 1 IEP RGD PMID:24782623 RGD:12879405 NCBI chr 7:63,156,926...63,169,579
Ensembl chr 7:63,156,926...63,169,251
JBrowse link
G Il1b interleukin 1 beta ISO RGD PMID:22173919 RGD:10044253 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 treatment IEP RGD PMID:22359633 RGD:11035224 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Ptch1 patched 1 IEP RGD PMID:24782623 RGD:12879405 NCBI chr17:1,542,705...1,607,730
Ensembl chr17:1,542,877...1,607,333
JBrowse link
G Smo smoothened, frizzled class receptor IEP RGD PMID:24782623 RGD:12879405 NCBI chr 4:58,344,101...58,372,828
Ensembl chr 4:58,343,529...58,373,829
JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 treatment IDA
IEP
protein:increased secretion:pancreatic juice: RGD PMID:19904222 PMID:12123090 PMID:22173919 RGD:10043091, RGD:10044261, RGD:10044253 NCBI chr18:35,870,723...35,882,693
Ensembl chr18:35,824,550...35,882,642
JBrowse link
G Tgfb1 transforming growth factor, beta 1 IEP RGD PMID:26645248 RGD:14995470 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 18133
    Animal Diseases 1692
      Animal Disease Models 1640
        Experimental Pancreatitis 42
          Acute Experimental Pancreatitis 31
          Chronic Experimental Pancreatitis 8
Path 2
Term Annotations click to browse term
  disease 18133
    disease of anatomical entity 17503
      endocrine system disease 6262
        pancreas disease 1155
          pancreatitis 214
            Experimental Pancreatitis 42
              Acute Experimental Pancreatitis 31
              Chronic Experimental Pancreatitis 8
paths to the root