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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Exfoliative Dermatitis
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Accession:DOID:9006215 term browser browse the term
Definition:The widespread involvement of the skin by a scaly, erythematous dermatitis occurring either as a secondary or reactive process to an underlying cutaneous disorder (e.g., atopic dermatitis, psoriasis, etc.), or as a primary or idiopathic disease. It is often associated with the loss of hair and nails, hyperkeratosis of the palms and soles, and pruritus. (From Dorland, 27th ed)
Synonyms:exact_synonym: Dermatitis Exfoliativa;   Erythroderma;   Erythrodermas;   Exfoliative Dermatitides
 primary_id: MESH:D003873
 alt_id: RDO:0000661
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
 
Exfoliative Dermatitis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Spink5 serine peptidase inhibitor, Kazal type 5 ISO ClinVar Annotator: match by term: Erythroderma ClinVar PMID:15304086 PMID:19683336 PMID:21255986 PMID:22089833 PMID:22377713 PMID:25665175 PMID:25741868 PMID:26229701 PMID:28289593 PMID:28492532 NCBI chr18:35,118,300...35,190,458
Ensembl chr18:35,121,967...35,191,069
Ensembl chr 1:35,121,967...35,191,069
JBrowse link
Congenital Erythroderma with Palmoplantar Keratoderma, Hypotrichosis, and Hyper-IgE term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dsg1 desmoglein 1 ISO ClinVar Annotator: match by OMIM:615508 OMIM
ClinVar
PMID:23974871 NCBI chr18:12,008,301...12,040,337
Ensembl chr18:12,008,759...12,038,053
JBrowse link
peeling skin syndrome term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdsn corneodesmosin ISO CTD Direct Evidence: marker/mechanism CTD NCBI chr20:3,704,626...3,707,266 JBrowse link
G Chst8 carbohydrate sulfotransferase 8 ISO CTD Direct Evidence: marker/mechanism CTD NCBI chr 1:90,542,095...90,685,257
Ensembl chr 1:90,542,096...90,685,257
JBrowse link
G Serpinb8 serpin family B member 8 ISO CTD Direct Evidence: marker/mechanism CTD NCBI chr13:27,876,662...27,914,038
Ensembl chr13:27,889,345...27,914,006
JBrowse link
Peeling Skin Syndrome 1 term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdsn corneodesmosin ISO ClinVar Annotator: match by term: Peeling skin syndrome 1 OMIM
ClinVar
PMID:2434123 PMID:20691404 PMID:21191406 PMID:22146835 PMID:23957618 NCBI chr20:3,704,626...3,707,266 JBrowse link
G Tgm5 transglutaminase 5 ISO ClinVar Annotator: match by term: Peeling skin syndrome 1 ClinVar PMID:22622422 NCBI chr 3:112,995,469...113,033,110
Ensembl chr 3:112,995,568...113,023,532
JBrowse link
Peeling Skin Syndrome 2 term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tgm5 transglutaminase 5 ISO ClinVar Annotator: match by OMIM:609796
ClinVar Annotator: match by term: Peeling skin syndrome 2
ClinVar Annotator: match by term: Peeling skin syndrome, acral type
ClinVar
OMIM
PMID:16380904 PMID:19440220 PMID:20164844 PMID:21469335 PMID:22036214 PMID:22622422 PMID:24019772 PMID:24628291 PMID:25644735 PMID:25741868 PMID:26091878 PMID:26707537 PMID:26925801 PMID:28492532 PMID:29242947 NCBI chr 3:112,995,469...113,033,110
Ensembl chr 3:112,995,568...113,023,532
JBrowse link
Peeling Skin Syndrome 3 term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chst8 carbohydrate sulfotransferase 8 ISO ClinVar Annotator: match by term: Peeling skin syndrome 3 OMIM
ClinVar
PMID:22289416 PMID:25741868 PMID:28492532 NCBI chr 1:90,542,095...90,685,257
Ensembl chr 1:90,542,096...90,685,257
JBrowse link
Peeling Skin Syndrome 4 term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csta cystatin A ISO ClinVar Annotator: match by OMIM:607936 OMIM
ClinVar
PMID:12890214 PMID:21944047 PMID:22066523 PMID:23534700 PMID:25400170 NCBI chr11:67,555,792...67,566,980
Ensembl chr11:67,555,658...67,566,972
JBrowse link
Peeling Skin Syndrome 5 term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Serpinb8 serpin family B member 8 ISO ClinVar Annotator: match by term: PEELING SKIN SYNDROME 5 ClinVar
OMIM
PMID:27476651 NCBI chr13:27,876,662...27,914,038
Ensembl chr13:27,889,345...27,914,006
JBrowse link
Peeling Skin Syndrome 6 term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Flg2 filaggrin family member 2 ISO ClinVar Annotator: match by term: PEELING SKIN SYNDROME 6
ClinVar Annotator: match by term: Peeling skin syndrome 6
ClinVar
OMIM
PMID:25741868 PMID:28884927 PMID:29505760 PMID:29758285 NCBI chr 2:193,480,880...193,485,463
Ensembl chr 2:193,483,793...193,485,313
JBrowse link
PEELING SKIN WITH LEUKONYCHIA, ACRAL PUNCTATE KERATOSES, CHEILITIS, AND KNUCKLE PADS term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cast calpastatin ISO ClinVar Annotator: match by OMIM:616295 ClinVar
OMIM
PMID:3527073 PMID:25683118 NCBI chr 2:1,452,111...1,561,669
Ensembl chr 2:1,452,116...1,561,464
JBrowse link
G Erap1 endoplasmic reticulum aminopeptidase 1 ISO ClinVar Annotator: match by term: PEELING SKIN WITH LEUKONYCHIA, ACRAL PUNCTATE KERATOSES, CHEILITIS, AND KNUCKLE PADS ClinVar PMID:3527073 PMID:25683118 NCBI chr 2:1,410,877...1,449,734
Ensembl chr 2:1,410,934...1,449,733
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 17150
    sensory system disease 5599
      skin disease 2948
        Eczematous Skin Diseases 261
          Exfoliative Dermatitis 10
            Congenital Erythroderma with Palmoplantar Keratoderma, Hypotrichosis, and Hyper-IgE 1
            Erythroderma Desquamativa of Leiner 0
            Lethal Congenital Erythroderma 0
            peeling skin syndrome + 8
Path 2
Term Annotations click to browse term
  disease 17150
    disease of anatomical entity 16494
      nervous system disease 12094
        sensory system disease 5599
          skin disease 2948
            dermatitis 422
              Exfoliative Dermatitis 10
                Congenital Erythroderma with Palmoplantar Keratoderma, Hypotrichosis, and Hyper-IgE 1
                Erythroderma Desquamativa of Leiner 0
                Lethal Congenital Erythroderma 0
                peeling skin syndrome + 8
paths to the root