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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Animal Disease Models
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Accession:DOID:9006205 term browser browse the term
Definition:Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
Synonyms:exact_synonym: Animal Disease Model
 primary_id: MESH:D004195
 alt_id: RDO:0005376
For additional species annotation, visit the Alliance of Genome Resources.



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Animal Disease Models term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB4 ATP binding cassette subfamily B member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16472600 PMID:29808285 NCBI chr14:13,542,610...13,614,334
Ensembl chr14:13,548,462...13,614,571
JBrowse link
G ABCC6 ATP binding cassette subfamily C member 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23415960 NCBI chr 6:27,800,060...27,849,170
Ensembl chr 6:27,798,835...27,848,689
JBrowse link
G ACSL4 acyl-CoA synthetase long chain family member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr  X:82,864,506...82,943,984
Ensembl chr  X:82,866,823...82,916,789
JBrowse link
G AHCY adenosylhomocysteinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr24:23,410,553...23,423,494
Ensembl chr24:23,411,140...23,419,767
JBrowse link
G AHR aryl hydrocarbon receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:27869817 NCBI chr14:31,743,704...31,793,484
Ensembl chr14:31,686,170...31,791,444
JBrowse link
G AIF1 allograft inflammatory factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27093858 NCBI chr12:1,104,350...1,106,179
Ensembl chr12:1,104,394...1,106,177
JBrowse link
G AKT1 AKT serine/threonine kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25658812 PMID:32045588 NCBI chr 8:72,317,399...72,335,686
Ensembl chr 8:72,317,869...72,335,193
JBrowse link
G ALB albumin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16642209 PMID:17963606 NCBI chr13:62,133,747...62,169,349
Ensembl chr13:62,053,814...62,294,709
JBrowse link
G ALDH18A1 aldehyde dehydrogenase 18 family member A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr28:9,101,578...9,148,063
Ensembl chr28:9,102,282...9,147,992
JBrowse link
G ALDH5A1 aldehyde dehydrogenase 5 family member A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29031482 NCBI chr35:22,560,005...22,590,996
Ensembl chr35:22,560,008...22,587,875
JBrowse link
G ALPL alkaline phosphatase, biomineralization associated ISO CTD Direct Evidence: marker/mechanism CTD PMID:27466191 NCBI chr 2:77,559,791...77,614,102
Ensembl chr 2:77,559,791...77,614,820
JBrowse link
G ANP32A acidic nuclear phosphoprotein 32 family member A ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr30:32,741,582...32,778,883
Ensembl chr30:32,741,582...32,798,188
JBrowse link
G APEX1 apurinic/apyrimidinic endodeoxyribonuclease 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr15:17,786,808...17,789,422
Ensembl chr15:17,786,357...17,789,422
JBrowse link
G APP amyloid beta precursor protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:12746438 PMID:16651627 PMID:25881725 PMID:27567873 PMID:31939705 NCBI chr31:21,351,207...21,614,466
Ensembl chr31:21,351,207...21,614,337
JBrowse link
G AQP4 aquaporin 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 7:61,855,617...61,868,953
Ensembl chr 7:61,855,744...61,865,089
JBrowse link
G ARG1 arginase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr12:242,717...255,736
Ensembl chr12:242,714...255,305
JBrowse link
G ARTN artemin ISO CTD Direct Evidence: marker/mechanism CTD PMID:27869817
G ATP7A ATPase copper transporting alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:17483305 NCBI chr  X:60,203,336...60,356,525
Ensembl chr  X:60,203,270...60,352,869
JBrowse link
G ATP7B ATPase copper transporting beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:11803042 PMID:15911138 PMID:21146535 PMID:21364284 NCBI chr22:162,474...225,599
Ensembl chr22:191,888...225,266
JBrowse link
G AXIN2 axin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29394407 NCBI chr 9:14,559,476...14,588,950
Ensembl chr 9:14,559,388...14,588,530
JBrowse link
G BDKRB2 bradykinin receptor B2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30685357 NCBI chr 8:64,974,588...65,005,682
Ensembl chr 8:64,974,997...65,003,407
JBrowse link
G BSCL2 BSCL2 lipid droplet biogenesis associated, seipin ISO CTD Direct Evidence: marker/mechanism CTD PMID:25462787 NCBI chr18:53,958,380...53,971,120
Ensembl chr18:53,958,475...53,971,119
JBrowse link
G BZW2 basic leucine zipper and W2 domains 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr14:31,154,285...31,217,193
Ensembl chr14:31,153,659...31,216,911
JBrowse link
G CA2 carbonic anhydrase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15816485 NCBI chr29:31,959,225...31,975,309
Ensembl chr29:31,935,172...31,980,579
JBrowse link
G CACNA1D calcium voltage-gated channel subunit alpha1 D ISO CTD Direct Evidence: marker/mechanism CTD PMID:26831068 NCBI chr20:36,189,986...36,488,460
Ensembl chr20:36,191,810...36,613,686
JBrowse link
G CALY calcyon neuron specific vesicular protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:30753204 NCBI chr28:40,918,341...40,925,161
Ensembl chr28:40,918,343...40,925,070
JBrowse link
G CCT5 chaperonin containing TCP1 subunit 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr34:4,035,851...4,049,131
Ensembl chr34:4,035,857...4,049,244
JBrowse link
G CDH2 cadherin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27811057 NCBI chr 7:60,736,760...60,950,477
Ensembl chr 7:60,736,760...60,951,034
JBrowse link
G CLDN11 claudin 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25911099 NCBI chr34:34,912,903...34,929,441
Ensembl chr34:34,912,449...34,928,433
JBrowse link
G CLN6 CLN6 transmembrane ER protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:23789114 NCBI chr30:32,246,394...32,264,251
Ensembl chr30:32,246,411...32,264,240
JBrowse link
G CLN8 CLN8 transmembrane ER and ERGIC protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:22302580 NCBI chr37:30,863,098...30,885,831
Ensembl chr37:30,867,479...30,884,895
JBrowse link
G CNR1 cannabinoid receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23072421 NCBI chr12:47,537,240...47,560,723
Ensembl chr12:47,509,583...47,560,983
JBrowse link
G CNR2 cannabinoid receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27317300 NCBI chr 2:75,640,636...75,662,000
Ensembl chr 2:75,658,999...75,660,126
JBrowse link
G COL2A1 collagen type II alpha 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:17299831 NCBI chr27:6,756,994...6,787,733
Ensembl chr27:6,756,994...6,787,733
JBrowse link
G CRSP-3 calcitonin receptor-stimulating peptide 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27093858 NCBI chr21:37,676,841...37,680,643
Ensembl chr21:37,676,841...37,680,645
JBrowse link
G CSF3 colony stimulating factor 3 ISO CTD Direct Evidence: therapeutic CTD PMID:27737899 NCBI chr 9:22,529,643...22,532,326
Ensembl chr 9:22,530,698...22,533,108
JBrowse link
G CSRP3 cysteine and glycine rich protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr21:41,300,277...41,318,788
Ensembl chr21:41,300,425...41,318,738
JBrowse link
G CTNNB1 catenin beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29394407 NCBI chr23:10,559,722...10,572,933
Ensembl chr23:10,559,718...10,572,927
JBrowse link
G CTU1 cytosolic thiouridylase subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27811057 NCBI chr 1:105,795,273...105,800,722 JBrowse link
G CTU2 cytosolic thiouridylase subunit 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27811057 NCBI chr 5:64,640,389...64,647,298
Ensembl chr 5:64,640,389...64,647,215
JBrowse link
G DEK DEK proto-oncogene ISO CTD Direct Evidence: marker/mechanism CTD PMID:27811057 NCBI chr35:17,014,802...17,045,308
Ensembl chr35:17,016,231...17,044,749
JBrowse link
G DHCR7 7-dehydrocholesterol reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:29698737 NCBI chr18:47,257,750...47,277,436
Ensembl chr18:47,261,730...47,274,236
JBrowse link
G DMD dystrophin ISO CTD Direct Evidence: marker/mechanism CTD PMID:22795790 PMID:26930420 PMID:30074247 NCBI chr  X:26,290,903...28,444,635
Ensembl chr  X:26,290,910...28,333,576
JBrowse link
G DSTN destrin, actin depolymerizing factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:29394407 NCBI chr24:5,394,972...5,402,443
Ensembl chr24:5,356,464...5,432,574
JBrowse link
G EIF2B1 eukaryotic translation initiation factor 2B subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr26:6,011,280...6,022,562
Ensembl chr26:6,011,301...6,022,518
JBrowse link
G EIF3E eukaryotic translation initiation factor 3 subunit E ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr13:8,834,724...8,887,818
Ensembl chr13:8,834,821...8,887,760
JBrowse link
G ELP3 elongator acetyltransferase complex subunit 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27811057 NCBI chr25:29,415,229...29,507,159
Ensembl chr25:29,415,924...29,507,098
JBrowse link
G ENO1 enolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 5:62,300,805...62,314,508
Ensembl chr 5:62,300,808...62,304,093
JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22302033 NCBI chr 9:22,760,373...22,785,367
Ensembl chr 9:22,759,256...22,785,294
JBrowse link
G ESR1 estrogen receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20962747 NCBI chr 1:42,081,952...42,368,544
Ensembl chr 1:42,081,969...42,368,544
JBrowse link
G F7 coagulation factor VII ISO CTD Direct Evidence: therapeutic CTD PMID:21127298 NCBI chr22:60,572,459...60,582,743
Ensembl chr22:60,571,822...60,597,024
JBrowse link
G FAS Fas cell surface death receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:22536412 PMID:26590112 NCBI chr26:38,738,811...38,763,298
Ensembl chr26:38,737,611...38,763,321
JBrowse link
G FASN fatty acid synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 9:233,105...249,573
Ensembl chr 9:232,963...249,092
JBrowse link
G FBL fibrillarin ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:113,632,899...113,643,805
Ensembl chr 1:113,632,929...113,643,748
JBrowse link
G FKBP11 FKBP prolyl isomerase 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr27:5,636,643...5,639,521
Ensembl chr27:5,636,627...5,639,509
JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:27093858 NCBI chr 8:48,330,856...48,334,273
Ensembl chr 8:48,331,026...48,333,467
JBrowse link
G GAPDH glyceraldehyde-3-phosphate dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr27:38,468,889...38,472,653
Ensembl chr27:38,468,889...38,472,385
JBrowse link
G GAR1 GAR1 ribonucleoprotein ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr32:29,995,710...30,004,545
Ensembl chr32:29,996,148...30,004,536
JBrowse link
G GATA4 GATA binding protein 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29394407 NCBI chr25:26,126,172...26,211,474
Ensembl chr25:26,127,853...26,182,989
JBrowse link
G GFAP glial fibrillary acidic protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:27093858 NCBI chr 9:18,569,868...18,579,463
Ensembl chr 9:18,569,892...18,579,461
JBrowse link
G GLI2 GLI family zinc finger 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27585885 NCBI chr19:29,128,401...29,383,324
Ensembl chr19:29,130,227...29,383,658
JBrowse link
G GNPNAT1 glucosamine-phosphate N-acetyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 8:28,992,173...29,005,511
Ensembl chr 8:28,993,227...29,005,435
JBrowse link
G GOLM1 golgi membrane protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:73,609,224...73,654,280
Ensembl chr 1:73,546,172...73,652,370
JBrowse link
G GPI glucose-6-phosphate isomerase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:117,922,380...117,948,325
Ensembl chr 1:117,922,635...117,948,316
JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27093858 NCBI chr 9:48,492,967...48,513,981
Ensembl chr 9:48,493,287...48,509,050
JBrowse link
G GRWD1 glutamate rich WD repeat containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:107,814,402...107,821,107
Ensembl chr 1:107,815,063...107,820,858
JBrowse link
G H1-10 H1.10 linker histone ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr20:2,799,360...2,800,524 JBrowse link
G H2BC4 H2B clustered histone 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr35:24,062,068...24,066,934
Ensembl chr35:24,066,399...24,066,779
JBrowse link
G HAND2 heart and neural crest derivatives expressed 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29394407 NCBI chr25:24,140,496...24,143,143
Ensembl chr25:24,141,243...24,152,958
JBrowse link
G HBEGF heparin binding EGF like growth factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:21937979 NCBI chr 2:35,551,248...35,563,310
Ensembl chr 2:35,551,250...35,563,043
JBrowse link
G HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19747469 NCBI chr 4:64,777,069...65,162,603
Ensembl chr 4:64,775,577...65,160,444
JBrowse link
G HELLS helicase, lymphoid specific ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr28:8,660,866...8,705,570
Ensembl chr28:8,661,008...8,705,580
JBrowse link
G HEYL hes related family bHLH transcription factor with YRPW motif like ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr15:3,242,738...3,257,275
Ensembl chr15:3,235,611...3,303,445
JBrowse link
G HK1 hexokinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 4:20,396,761...20,516,889
Ensembl chr 4:20,421,526...20,518,211
JBrowse link
G HK2 hexokinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr17:48,287,367...48,329,470
Ensembl chr17:48,289,272...48,348,663
JBrowse link
G HMGB2 high mobility group box 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr25:23,939,024...23,941,720
Ensembl chr25:23,939,027...23,941,606
JBrowse link
G HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr27:1,013,459...1,020,083
Ensembl chr27:1,015,868...1,019,891
JBrowse link
G IDH2 isocitrate dehydrogenase (NADP(+)) 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27469509 NCBI chr 3:53,070,462...53,077,566
Ensembl chr 3:53,070,695...53,087,496
JBrowse link
G IFNG interferon gamma ISO CTD Direct Evidence: therapeutic CTD PMID:16845661 NCBI chr10:10,406,866...10,411,698
Ensembl chr10:10,406,867...10,411,698
JBrowse link
G IL10 interleukin 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27580383 PMID:28411859 NCBI chr 7:5,933,285...5,937,057
Ensembl chr 7:5,933,285...5,937,057
JBrowse link
G IL1B interleukin 1 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:27093858 NCBI chr17:37,019,329...37,033,388
Ensembl chr17:37,019,329...37,024,458
JBrowse link
G IMPDH2 inosine monophosphate dehydrogenase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr20:40,136,106...40,140,983
Ensembl chr20:40,136,154...40,140,972
JBrowse link
G IPO4 importin 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 8:4,171,525...4,180,666
Ensembl chr 8:4,171,527...4,181,151
JBrowse link
G IPO5 importin 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr22:48,126,053...48,182,897
Ensembl chr22:48,136,242...48,180,495
JBrowse link
G IRAK4 interleukin 1 receptor associated kinase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28003376 NCBI chr27:10,313,782...10,340,652
Ensembl chr27:10,314,187...10,340,682
JBrowse link
G KL klotho ISO CTD Direct Evidence: marker/mechanism CTD PMID:25550330 NCBI chr25:7,154,359...7,201,744
Ensembl chr25:7,156,620...7,199,558
JBrowse link
G KNG1 kininogen 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30685357 NCBI chr34:19,288,629...19,318,096
Ensembl chr34:19,287,109...19,318,081
JBrowse link
G KPNA2 karyopherin subunit alpha 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 9:12,546,912...12,556,163 JBrowse link
G KRAS KRAS proto-oncogene, GTPase ISO CTD Direct Evidence: marker/mechanism CTD PMID:26390243 PMID:27588471 PMID:33380422 NCBI chr27:22,261,753...22,296,704
Ensembl chr27:22,257,941...22,293,369
JBrowse link
G LDHA lactate dehydrogenase A ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr21:40,829,844...40,840,947 JBrowse link
G LEF1 lymphoid enhancer binding factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27811057 NCBI chr32:28,516,002...28,633,759
Ensembl chr32:28,517,108...28,634,019
JBrowse link
G LMNB1 lamin B1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr11:15,996,627...16,052,719
Ensembl chr11:15,930,436...16,052,127
JBrowse link
G LOC102155800 60S ribosomal protein L36a-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr17:52,628,292...52,628,713 JBrowse link
G LOC487740 trifunctional purine biosynthetic protein adenosine-3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr31:29,032,399...29,063,706 JBrowse link
G LOC609402 hemoglobin subunit beta-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:23975182 PMID:29255069 NCBI chr21:28,187,535...28,188,991 JBrowse link
G MAPK1 mitogen-activated protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27093858 NCBI chr26:31,013,607...31,132,998
Ensembl chr26:31,013,607...31,132,998
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27093858 NCBI chr 6:18,109,184...18,115,728
Ensembl chr 6:18,109,222...18,114,425
JBrowse link
G MAPK8 mitogen-activated protein kinase 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27093858 NCBI chr28:323,361...410,367
Ensembl chr28:368,513...406,401
JBrowse link
G MAPK9 mitogen-activated protein kinase 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27093858 NCBI chr11:1,443,528...1,480,501
Ensembl chr11:1,443,547...1,478,119
JBrowse link
G MAPT microtubule associated protein tau ISO CTD Direct Evidence: marker/mechanism CTD PMID:24556215 NCBI chr 9:9,572,174...9,674,082
Ensembl chr 9:9,570,557...9,674,349
JBrowse link
G MECP2 methyl-CpG binding protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28592917 PMID:33010341 NCBI chr  X:121,866,721...121,876,088
Ensembl chr  X:121,873,218...121,932,994
JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:32045588 NCBI chr14:55,599,047...55,711,626
Ensembl chr14:55,598,337...55,724,027
JBrowse link
G MKI67IP MKI67 (FHA domain) interacting nucleolar phosphoprotein EXP CTD Direct Evidence: marker/mechanism CTD PMID:27602772
G MMP9 matrix metallopeptidase 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21051829 NCBI chr24:33,274,260...33,281,116
Ensembl chr24:33,274,268...33,281,293
JBrowse link
G MRE11 MRE11 homolog, double strand break repair nuclease ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr21:6,448,909...6,528,185
Ensembl chr21:6,449,822...6,527,119
JBrowse link
G MRPL12 mitochondrial ribosomal protein L12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 9:493,536...498,154 JBrowse link
G MRPS5 mitochondrial ribosomal protein S5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr17:34,926,674...34,952,665
Ensembl chr17:34,926,743...34,952,473
JBrowse link
G MYBPC3 myosin binding protein C3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25566086 NCBI chr18:42,271,159...42,288,782
Ensembl chr18:42,271,724...42,289,215
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr13:25,200,772...25,205,309
Ensembl chr13:25,200,577...25,205,309
JBrowse link
G NAA10 N-alpha-acetyltransferase 10, NatA catalytic subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr  X:121,777,658...121,782,097
Ensembl chr  X:121,727,573...121,788,860
JBrowse link
G NCL nucleolin ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr25:43,330,524...43,384,909
Ensembl chr25:43,330,799...43,384,258
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:27012417 PMID:29255069 NCBI chr36:20,989,205...21,087,044
Ensembl chr36:20,989,360...21,012,524
JBrowse link
G NOP56 NOP56 ribonucleoprotein ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr24:18,561,407...18,566,770
Ensembl chr24:18,561,408...18,566,719
JBrowse link
G NOP58 NOP58 ribonucleoprotein ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr37:11,255,562...11,287,325
Ensembl chr37:11,255,589...11,287,279
JBrowse link
G NPHP3 nephrocystin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12089381 NCBI chr23:29,662,486...29,703,629
Ensembl chr23:29,645,641...29,703,805
JBrowse link
G NPM1 nucleophosmin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 4:40,756,464...40,770,174
Ensembl chr 4:40,756,465...40,770,175
JBrowse link
G NPM3 nucleophosmin/nucleoplasmin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr28:14,373,446...14,375,624
Ensembl chr28:14,373,452...14,404,541
JBrowse link
G NPPB natriuretic peptide B ISO CTD Direct Evidence: marker/mechanism CTD PMID:29394407 NCBI chr 2:84,395,844...84,397,473 JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29142166 PMID:32062620 NCBI chr15:39,497,313...39,608,120
Ensembl chr15:39,536,290...39,608,116
JBrowse link
G NUDT21 nudix hydrolase 21 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 2:59,736,739...59,751,967
Ensembl chr 2:59,736,186...59,751,704
JBrowse link
G NUS1 NUS1 dehydrodolichyl diphosphate synthase subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:33812996 NCBI chr 1:57,866,760...57,895,505
Ensembl chr 1:57,866,879...57,893,077
JBrowse link
G P2RX7 purinergic receptor P2X 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27466191 NCBI chr26:7,928,863...7,983,956
Ensembl chr26:7,940,985...7,983,740
JBrowse link
G PCBD1 pterin-4 alpha-carbinolamine dehydratase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 4:21,719,863...21,723,493
Ensembl chr 4:21,719,863...21,721,574
JBrowse link
G PDE6B phosphodiesterase 6B ISO CTD Direct Evidence: marker/mechanism CTD PMID:17213800 NCBI chr 3:91,746,571...91,775,372
Ensembl chr 3:91,746,571...91,775,372
JBrowse link
G PIGN phosphatidylinositol glycan anchor biosynthesis class N ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:14,684,026...14,791,221
Ensembl chr 1:14,685,694...14,805,691
JBrowse link
G PIM1 Pim-1 proto-oncogene, serine/threonine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25812446 NCBI chr12:6,213,504...6,217,933
Ensembl chr12:6,211,867...6,217,933
JBrowse link
G PKD1 polycystin 1, transient receptor potential channel interacting ISO CTD Direct Evidence: marker/mechanism CTD PMID:25877301 NCBI chr 6:38,811,051...38,865,503
Ensembl chr 6:38,837,964...38,865,503
JBrowse link
G POLR1D RNA polymerase I and III subunit D ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr25:11,997,020...11,998,742 JBrowse link
G PPAN peter pan homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr20:50,949,138...50,952,843
Ensembl chr20:50,949,138...50,952,843
JBrowse link
G PRKCG protein kinase C gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:27093858 NCBI chr 1:103,295,110...103,312,562 JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase ISO CTD Direct Evidence: marker/mechanism CTD PMID:15882845 NCBI chr 1:49,886,887...51,201,930
Ensembl chr 1:49,889,005...51,201,764
JBrowse link
G PSAT1 phosphoserine aminotransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:80,376,469...80,408,177
Ensembl chr 1:80,377,115...80,408,162
JBrowse link
G PSEN1 presenilin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16651627 PMID:27567873 NCBI chr 8:46,495,551...46,569,532
Ensembl chr 8:46,495,624...46,569,532
JBrowse link
G PTH parathyroid hormone ISO CTD Direct Evidence: therapeutic CTD PMID:30639440 NCBI chr21:36,417,062...36,419,967
Ensembl chr21:36,417,058...36,419,967
JBrowse link
G RANGRF RAN guanine nucleotide release factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 5:33,084,355...33,085,810
Ensembl chr 5:33,084,397...33,085,812
JBrowse link
G RCL1 RNA terminal phosphate cyclase like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:93,144,164...93,204,233
Ensembl chr 1:93,142,635...93,435,997
JBrowse link
G RFC4 replication factor C subunit 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr34:19,361,024...19,377,289
Ensembl chr34:19,361,044...19,377,294
JBrowse link
G RHOA ras homolog family member A ISO CTD Direct Evidence: marker/mechanism CTD PMID:25783350 NCBI chr20:39,824,552...39,888,089
Ensembl chr20:39,824,575...39,887,215
JBrowse link
G ROCK2 Rho associated coiled-coil containing protein kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29394407 NCBI chr17:7,931,786...8,012,484
Ensembl chr17:7,934,739...8,178,707
JBrowse link
G RPL10A ribosomal protein L10a ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr12:4,601,760...4,604,142
Ensembl chr12:4,601,766...4,604,220
JBrowse link
G RPL13A ribosomal protein L13a ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:107,010,190...107,014,267
Ensembl chr 1:107,010,190...107,014,267
JBrowse link
G RPL27A ribosomal protein L27a ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr21:32,099,792...32,102,761
Ensembl chr21:32,099,792...32,102,754
JBrowse link
G RPSA ribosomal protein SA ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr23:9,070,953...9,077,058
Ensembl chr23:9,070,953...9,077,057
JBrowse link
G RRM1 ribonucleotide reductase catalytic subunit M1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr21:26,595,838...26,631,476
Ensembl chr21:26,595,914...26,631,135
JBrowse link
G RRM2 ribonucleotide reductase regulatory subunit M2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr17:7,106,515...7,113,868
Ensembl chr17:7,104,961...7,122,939
JBrowse link
G RRS1 ribosome biogenesis regulator 1 homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr29:16,016,134...16,018,046
Ensembl chr29:16,016,189...16,017,286
JBrowse link
G S100A10 S100 calcium binding protein A10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21682946 NCBI chr17:60,984,138...60,994,915 JBrowse link
G S100B S100 calcium binding protein B ISO CTD Direct Evidence: marker/mechanism CTD PMID:12888777 NCBI chr31:39,783,990...39,788,289
Ensembl chr31:39,784,506...39,788,183
JBrowse link
G SATB1 SATB homeobox 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr23:24,614,198...24,692,254
Ensembl chr23:24,593,489...24,690,977
JBrowse link
G SERPINE1 serpin family E member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21051829 NCBI chr 6:8,719,547...8,727,160
Ensembl chr 6:8,720,825...8,726,301
JBrowse link
G SFXN1 sideroflexin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 4:37,485,360...37,517,743
Ensembl chr 4:37,487,438...37,512,289
JBrowse link
G SH3PXD2B SH3 and PX domains 2B ISO CTD Direct Evidence: marker/mechanism CTD PMID:28719234 NCBI chr 4:39,854,213...39,950,704
Ensembl chr 4:39,854,211...39,949,958
JBrowse link
G SHMT1 serine hydroxymethyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 5:41,221,531...41,248,653
Ensembl chr 5:41,221,562...41,253,166
JBrowse link
G SLC15A2 solute carrier family 15 member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr33:25,154,415...25,190,715
Ensembl chr33:25,154,448...25,189,929
JBrowse link
G SLC19A1 solute carrier family 19 member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr31:38,958,332...38,971,091
Ensembl chr31:38,967,013...38,971,094
JBrowse link
G SLC29A1 solute carrier family 29 member 1 (Augustine blood group) ISO CTD Direct Evidence: marker/mechanism CTD PMID:27567601 NCBI chr12:12,632,233...12,644,669
Ensembl chr12:12,634,194...12,644,667
JBrowse link
G SLC4A4 solute carrier family 4 member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr13:60,375,215...60,670,664
Ensembl chr13:60,328,136...60,666,728
JBrowse link
G SLC4A7 solute carrier family 4 member 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr23:16,710,649...16,788,277
Ensembl chr23:16,710,701...16,785,541
JBrowse link
G SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr20:41,165,593...41,337,237
Ensembl chr20:41,165,522...41,335,917
JBrowse link
G SNCA synuclein alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:21892157 PMID:26075822 NCBI chr32:12,915,871...13,079,338
Ensembl chr32:12,916,215...13,060,383
JBrowse link
G SNRPG small nuclear ribonucleoprotein polypeptide G ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr10:68,826,250...68,836,755
Ensembl chr10:68,826,250...68,836,755
Ensembl chr10:68,826,250...68,836,755
JBrowse link
G SOD1 superoxide dismutase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12586733 PMID:12684256 PMID:19227972 PMID:20177826 PMID:21867702 More... NCBI chr31:26,540,291...26,544,212
Ensembl chr31:26,486,274...26,662,815
JBrowse link
G SRM spermidine synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 2:84,968,833...84,973,111
Ensembl chr 2:84,967,570...84,973,087
JBrowse link
G SRR serine racemase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772
G STAT3 signal transducer and activator of transcription 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25812446 NCBI chr 9:20,539,660...20,614,631
Ensembl chr 9:20,539,697...20,612,672
JBrowse link
G STK39 serine/threonine kinase 39 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr36:12,866,867...13,118,736
Ensembl chr36:12,867,188...13,183,160
JBrowse link
G STRBP spermatid perinuclear RNA binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 9:59,543,172...59,689,035
Ensembl chr 9:59,614,129...59,689,032
JBrowse link
G SUCLG2 succinate-CoA ligase GDP-forming subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr20:23,915,149...24,167,740
Ensembl chr20:23,895,802...24,182,869
JBrowse link
G TBX20 T-box transcription factor 20 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29394407 NCBI chr14:46,891,706...46,946,899
Ensembl chr14:46,896,228...46,947,507
JBrowse link
G TCF7L2 transcription factor 7 like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29394407 NCBI chr28:23,966,079...24,162,775
Ensembl chr28:23,966,073...24,163,737
JBrowse link
G TFAM transcription factor A, mitochondrial ISO CTD Direct Evidence: marker/mechanism CTD PMID:28595911 NCBI chr 4:10,585,320...10,600,664
Ensembl chr 4:10,585,480...10,598,058
JBrowse link
G TG thyroglobulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:30373627 NCBI chr13:29,350,726...29,597,908
Ensembl chr13:29,350,688...29,598,040
JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27228633 NCBI chr11:56,191,383...56,223,042
Ensembl chr11:56,161,772...56,218,594
JBrowse link
G TIMM10 translocase of inner mitochondrial membrane 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr18:38,638,277...38,641,623
Ensembl chr18:38,638,696...38,641,623
JBrowse link
G TIMM8A translocase of inner mitochondrial membrane 8A ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr  X:75,267,437...75,270,288
Ensembl chr  X:75,267,450...75,270,288
JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21051829 NCBI chr  X:41,201,623...41,205,314
Ensembl chr  X:41,201,638...41,205,310
JBrowse link
G TK1 thymidine kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 9:2,959,450...2,970,908
Ensembl chr 9:2,959,488...2,971,064
JBrowse link
G TNF tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:27093858 NCBI chr12:1,074,561...1,076,425
Ensembl chr12:1,074,552...1,076,425
JBrowse link
G TOMM40 translocase of outer mitochondrial membrane 40 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:110,530,233...110,541,049
Ensembl chr 1:110,530,597...110,541,042
JBrowse link
G TOP2A DNA topoisomerase II alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 9:22,207,501...22,237,497
Ensembl chr 9:22,207,638...22,237,496
JBrowse link
G TP53 tumor protein p53 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23873029 NCBI chr 5:32,561,406...32,565,149
Ensembl chr 5:32,560,598...32,574,109
JBrowse link
G TPI1 triosephosphate isomerase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr27:38,154,519...38,157,900
Ensembl chr27:38,154,519...38,158,137
JBrowse link
G TTPA alpha tocopherol transfer protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:11095717 PMID:11752462 NCBI chr29:13,177,690...13,198,910
Ensembl chr29:13,182,308...13,192,553
JBrowse link
G TYMS thymidylate synthetase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 7:67,487,927...67,497,747
Ensembl chr 7:67,487,927...67,497,747
JBrowse link
G UCK2 uridine-cytidine kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr38:17,475,789...17,555,926
Ensembl chr38:17,479,558...17,579,675
JBrowse link
G VCP valosin containing protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:25884947 NCBI chr11:51,636,986...51,651,749
Ensembl chr11:51,637,411...51,651,714
JBrowse link
G VIM vimentin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16831193 NCBI chr 2:19,671,316...19,679,367
Ensembl chr 2:19,671,316...19,679,466
JBrowse link
G WNT11 Wnt family member 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25783350 NCBI chr21:22,442,496...22,463,040
Ensembl chr21:22,446,051...22,463,173
JBrowse link
G XRCC5 X-ray repair cross complementing 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr37:23,095,769...23,185,680
Ensembl chr37:23,095,754...23,185,586
JBrowse link
G XRCC6 X-ray repair cross complementing 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr10:23,637,905...23,661,618
Ensembl chr10:23,638,237...23,661,480
JBrowse link
Acute Experimental Autoimmune Encephalomyelitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MAG myelin associated glycoprotein ISO protein:decreased expression:optic nerve RGD PMID:9820787 RGD:9685300 NCBI chr 1:117,288,306...117,301,975
Ensembl chr 1:117,288,343...117,302,386
JBrowse link
G ZC3H12A zinc finger CCCH-type containing 12A disease_progression ISO RGD PMID:26320658 RGD:11534569 NCBI chr15:4,972,369...4,984,218
Ensembl chr15:4,972,956...4,980,371
JBrowse link
Acute Experimental Pancreatitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 treatment ISO RGD PMID:18416460 RGD:13782074 NCBI chr26:8,148,181...8,209,392
Ensembl chr26:8,148,236...8,209,388
JBrowse link
G BCL2L1 BCL2 like 1 ISO protein:increased expression:pancreas, mitochondrion (rat) RGD PMID:19331832 RGD:11353791 NCBI chr24:21,145,214...21,209,425
Ensembl chr24:21,145,215...21,196,355
JBrowse link
G BECN1 beclin 1 treatment ISO RGD PMID:22850625 RGD:11560530 NCBI chr 9:20,204,203...20,215,081
Ensembl chr 9:20,204,220...20,214,236
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A ISO RGD PMID:10451498 RGD:10043817 NCBI chr12:5,746,898...5,755,103
Ensembl chr12:5,745,852...5,892,281
JBrowse link
G EDNRA endothelin receptor type A treatment ISO RGD PMID:12799311 RGD:1581841 NCBI chr15:45,823,472...45,878,527
Ensembl chr15:45,823,560...45,876,463
JBrowse link
G FAS Fas cell surface death receptor severity ISO protein:increased expression:Kupffer cell: RGD PMID:15797225 RGD:14700708 NCBI chr26:38,738,811...38,763,298
Ensembl chr26:38,737,611...38,763,321
JBrowse link
G FASLG Fas ligand severity ISO protein:increased expression:Kupffer cell: RGD PMID:15797225 RGD:14700708 NCBI chr 7:26,335,837...26,344,224
Ensembl chr 7:26,335,846...26,344,224
JBrowse link
G GSS glutathione synthetase ISO RGD PMID:17897920 RGD:11353819 NCBI chr24:23,973,807...24,000,281
Ensembl chr24:23,901,045...23,997,286
JBrowse link
G HMGB1 high mobility group box 1 treatment ISO RGD PMID:23706497 RGD:10402063 NCBI chr25:9,431,223...9,558,167
Ensembl chr25:9,431,218...9,558,165
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 ISO protein:increased expression:neutrophil: RGD PMID:26464680 RGD:11354914 NCBI chr 9:57,850,870...57,855,607
Ensembl chr 9:57,850,922...57,855,257
JBrowse link
G ICAM1 intercellular adhesion molecule 1 treatment ISO RGD PMID:10201790 PMID:23706497 RGD:10402063 RGD:11520782 NCBI chr20:50,818,715...50,827,914
Ensembl chr20:50,818,715...50,827,914
JBrowse link
G IL10 interleukin 10 treatment ISO RGD PMID:25323753 RGD:11049477 NCBI chr 7:5,933,285...5,937,057
Ensembl chr 7:5,933,285...5,937,057
JBrowse link
G IL4 interleukin 4 treatment ISO RGD PMID:24876883 RGD:10402805 NCBI chr11:20,972,693...20,981,539
Ensembl chr11:20,972,690...20,981,534
JBrowse link
G JAK1 Janus kinase 1 treatment ISO RGD PMID:21369693 RGD:19165136 NCBI chr 5:45,251,653...45,408,571
Ensembl chr 5:45,251,653...45,408,571
JBrowse link
G KMO kynurenine 3-monooxygenase disease_progression ISO RGD PMID:26752518 PMID:28398044 RGD:11342439 RGD:13703053 NCBI chr 7:32,941,487...32,994,541
Ensembl chr 7:32,941,487...32,994,541
JBrowse link
G KRAS KRAS proto-oncogene, GTPase ISO RGD PMID:8913708 RGD:11062095 NCBI chr27:22,261,753...22,296,704
Ensembl chr27:22,257,941...22,293,369
JBrowse link
G LAMP2 lysosomal associated membrane protein 2 ISO protein:decreased expression:pancreas RGD PMID:22850625 RGD:11560530 NCBI chr  X:92,405,946...92,444,527
Ensembl chr  X:92,407,950...92,444,765
JBrowse link
G MAP1LC3A microtubule associated protein 1 light chain 3 alpha treatment ISO RGD PMID:22850625 RGD:11560530 NCBI chr24:23,672,343...23,673,937
Ensembl chr24:23,633,579...23,673,921
JBrowse link
G MIR155 microRNA mir-155 treatment ISO RGD PMID:29937734 PMID:30497068 RGD:21403683 RGD:21408596 NCBI chr31:21,078,768...21,078,828
Ensembl chr31:21,078,758...21,078,833
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 ISO RGD PMID:16127429 RGD:11075069 NCBI chr 7:38,503,072...38,542,556
Ensembl chr 7:38,503,067...38,542,127
JBrowse link
G PROC protein C, inactivator of coagulation factors Va and VIIIa treatment ISO RGD PMID:19680809 RGD:11100040 NCBI chr19:23,173,626...23,183,634
Ensembl chr19:23,173,635...23,183,563
JBrowse link
G PROCR protein C receptor treatment ISO protein:increased expression:blood RGD PMID:24749346 PMID:25688263 RGD:13515127 RGD:13515128 NCBI chr24:24,184,063...24,188,452
Ensembl chr24:24,184,370...24,187,910
JBrowse link
G PTAFR platelet activating factor receptor treatment ISO RGD PMID:21633536 RGD:9999225 NCBI chr 2:72,225,386...72,256,353
Ensembl chr 2:72,225,386...72,256,352
JBrowse link
G SERPINC1 serpin family C member 1 treatment ISO RGD PMID:19546838 RGD:11035262 NCBI chr 7:25,322,668...25,333,022
Ensembl chr 7:25,316,129...25,332,987
JBrowse link
G SPINK1 serine peptidase inhibitor Kazal type 1 treatment ISO RGD PMID:15765407 RGD:10043090 NCBI chr 2:42,112,015...42,120,738
Ensembl chr 2:42,112,016...42,120,706
JBrowse link
G TNF tumor necrosis factor ISO associated with Anemia, Hemolytic RGD PMID:12845374 PMID:15164724 RGD:10449461 RGD:1580295 NCBI chr12:1,074,561...1,076,425
Ensembl chr12:1,074,552...1,076,425
JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A ISO protein:increased expression:serum RGD PMID:15164724 RGD:1580295 NCBI chr27:38,641,837...38,654,693
Ensembl chr27:38,638,753...38,700,282
JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B ISO protein:increased expression:serum RGD PMID:15164724 RGD:1580295 NCBI chr 2:84,140,179...84,151,219
Ensembl chr 2:84,141,911...84,157,191
JBrowse link
G VWF von Willebrand factor ISO protein:increased expression:plasma: RGD PMID:17708840 RGD:11079229 NCBI chr27:38,834,812...38,972,614
Ensembl chr27:38,833,837...39,320,142
JBrowse link
Avian Sarcoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RHOB ras homolog family member B ISO RGD PMID:1710770 RGD:704375 NCBI chr17:15,438,744...15,439,793
Ensembl chr17:15,439,143...15,441,136
JBrowse link
Carcinoma, Lewis Lung term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 treatment ISO RGD PMID:16947020 RGD:7401280 NCBI chr20:53,566,226...53,598,365
Ensembl chr20:53,566,261...53,598,761
JBrowse link
G COQ7 coenzyme Q7, hydroxylase susceptibility ISO RGD PMID:23166727 RGD:10402105 NCBI chr 6:25,912,936...25,922,123
Ensembl chr 6:25,912,954...25,929,655
JBrowse link
G CSF1R colony stimulating factor 1 receptor ameliorates ISO mouse cell line in a mouse model RGD PMID:20008303 RGD:150524291 NCBI chr 4:58,980,699...59,010,683
Ensembl chr 4:58,980,788...59,010,510
JBrowse link
G IL18 interleukin 18 treatment ISO RGD PMID:16767432 RGD:8655941 NCBI chr 5:20,972,742...20,995,327
Ensembl chr 5:20,972,871...20,995,348
JBrowse link
G IL2 interleukin 2 treatment ISO RGD PMID:9399664 RGD:8663451 NCBI chr19:17,750,780...17,756,394
Ensembl chr19:17,750,780...17,756,394
JBrowse link
G IRAK3 interleukin 1 receptor associated kinase 3 ISO RGD PMID:21278795 RGD:36049796 NCBI chr10:8,683,541...8,730,757
Ensembl chr10:8,684,242...8,729,268
JBrowse link
G JAM3 junctional adhesion molecule 3 ISO RGD PMID:15994945 RGD:7488936 NCBI chr 5:1,082,619...1,165,188
Ensembl chr 5:1,084,560...1,165,121
JBrowse link
G LECT2 leukocyte cell derived chemotaxin 2 ISO CTD Direct Evidence: therapeutic CTD PMID:30453282 NCBI chr11:23,864,062...23,873,720
Ensembl chr11:23,864,064...23,886,226
JBrowse link
G MAPK14 mitogen-activated protein kinase 14 ameliorates ISO mouse cell line in a mouse model RGD PMID:29907597 RGD:151665504 NCBI chr12:5,145,647...5,221,558
Ensembl chr12:5,146,037...5,220,603
JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor treatment ISO mouse cell line in a mouse model RGD PMID:26111447 RGD:150521531 NCBI chr23:7,901,578...7,905,274
Ensembl chr23:7,901,250...7,904,534
JBrowse link
G TXNRD1 thioredoxin reductase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16565519 NCBI chr10:33,904,065...34,021,549
Ensembl chr10:33,886,343...34,021,696
JBrowse link
Choroidal Neovascularization, Experimental term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SERPINE1 serpin family E member 1 severity
treatment
ISO human gene in mouse model
mRNA:increased expression:retina (mouse)
RGD PMID:11292663 PMID:12766088 PMID:26610445 RGD:11073722 RGD:8547735 RGD:8547737 NCBI chr 6:8,719,547...8,727,160
Ensembl chr 6:8,720,825...8,726,301
JBrowse link
G SMO smoothened, frizzled class receptor treatment ISO RGD PMID:21063852 RGD:12859045 NCBI chr14:7,518,871...7,527,703
Ensembl chr14:7,518,856...7,528,033
JBrowse link
Chronic Experimental Pancreatitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B9D2 B9 domain containing 2 ISO RGD PMID:26645248 RGD:14995470 NCBI chr 1:112,621,832...112,627,726
Ensembl chr 1:112,621,633...112,643,885
JBrowse link
G CBS cystathionine beta-synthase ISO protein:increased expression:arcuate nucleus (rat) RGD PMID:27778022 RGD:38456012 NCBI chr31:37,230,900...37,247,170 JBrowse link
G GLI1 GLI family zinc finger 1 ISO RGD PMID:24782623 RGD:12879405 NCBI chr10:1,565,306...1,575,971
Ensembl chr10:1,565,244...1,575,982
JBrowse link
G IL1B interleukin 1 beta ISO RGD PMID:22173919 RGD:10044253 NCBI chr17:37,019,329...37,033,388
Ensembl chr17:37,019,329...37,024,458
JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 treatment ISO RGD PMID:22359633 RGD:11035224 NCBI chr 5:79,979,593...79,990,875
Ensembl chr 5:79,978,865...79,989,860
JBrowse link
G PTCH1 patched 1 ISO RGD PMID:24782623 RGD:12879405 NCBI chr 1:71,246,750...71,309,036
Ensembl chr 1:71,238,195...71,305,662
JBrowse link
G SMO smoothened, frizzled class receptor ISO RGD PMID:24782623 RGD:12879405 NCBI chr14:7,518,871...7,527,703
Ensembl chr14:7,518,856...7,528,033
JBrowse link
G SPINK1 serine peptidase inhibitor Kazal type 1 treatment ISO protein:increased secretion:pancreatic juice: RGD PMID:12123090 PMID:19904222 PMID:22173919 RGD:10043091 RGD:10044253 RGD:10044261 NCBI chr 2:42,112,015...42,120,738
Ensembl chr 2:42,112,016...42,120,706
JBrowse link
Chronic Relapsing Experimental Autoimmune Encephalomyelitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL2 C-C motif chemokine ligand 2 ISO mRNA:increased expression:spinal cord (rat) RGD PMID:12098510 RGD:8655962 NCBI chr 9:39,008,187...39,009,932 JBrowse link
G NEFH neurofilament heavy chain ISO protein:decreased expression:spinal cord: RGD PMID:12742652 RGD:27226817 NCBI chr26:22,726,523...22,735,129
Ensembl chr26:22,726,526...22,735,125
JBrowse link
G PLP1 proteolipid protein 1 ISO human sequence peptide in a mouse model; associated with Herpesviridae infections RGD PMID:12811845 RGD:30296670 NCBI chr  X:77,191,112...77,207,772
Ensembl chr  X:77,191,150...77,205,964
JBrowse link
G SERPINE1 serpin family E member 1 ISO RGD PMID:17983428 RGD:13208507 NCBI chr 6:8,719,547...8,727,160
Ensembl chr 6:8,720,825...8,726,301
JBrowse link
Ehrlich tumor carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD40 CD40 molecule treatment ISO RGD PMID:19269163 RGD:11352683 NCBI chr24:33,352,992...33,383,488
Ensembl chr24:33,372,930...33,383,301
JBrowse link
G CD40LG CD40 ligand treatment ISO RGD PMID:19269163 RGD:11352683 NCBI chr  X:107,001,421...107,023,007
Ensembl chr  X:107,010,890...107,023,006
JBrowse link
G CEACAM20 CEA cell adhesion molecule 20 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34605108 NCBI chr 1:110,744,921...110,829,413
Ensembl chr 1:110,805,089...110,827,606
JBrowse link
Experimental Allergic Asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACSL3 acyl-CoA synthetase long chain family member 3 ISO RGD PMID:23526225 RGD:13831300 NCBI chr37:28,882,264...28,929,451
Ensembl chr37:28,864,147...28,938,866
JBrowse link
G BCL2 BCL2 apoptosis regulator treatment ISO RGD PMID:29713367 RGD:13792581 NCBI chr 1:13,733,849...13,900,653
Ensembl chr 1:13,731,406...13,900,658
JBrowse link
G CD86 CD86 molecule treatment ISO RGD PMID:25344652 RGD:11354965 NCBI chr33:25,256,267...25,318,855
Ensembl chr33:25,256,267...25,318,087
JBrowse link
G FAS Fas cell surface death receptor treatment ISO RGD PMID:29713367 RGD:13792581 NCBI chr26:38,738,811...38,763,298
Ensembl chr26:38,737,611...38,763,321
JBrowse link
G FASLG Fas ligand treatment ISO RGD PMID:29713367 RGD:13792581 NCBI chr 7:26,335,837...26,344,224
Ensembl chr 7:26,335,846...26,344,224
JBrowse link
G IL23A interleukin 23 subunit alpha ISO RGD PMID:19935773 PMID:26344076 RGD:11251537 RGD:5037240 NCBI chr10:635,384...640,715
Ensembl chr10:638,719...640,359
JBrowse link
Experimental Arthritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 ISO CTD Direct Evidence: marker/mechanism
mRNA:decreased expression:intestinal mucosa (rat)
mRNA:altered expression:liver
CTD
RGD
PMID:17827786 PMID:19152228 RGD:11040994 RGD:2315573 NCBI chr14:13,644,891...13,852,829
Ensembl chr14:13,542,647...13,742,727
JBrowse link
G ABCC6 ATP binding cassette subfamily C member 6 ISO mRNA:decreased expression:kidney RGD PMID:22974786 RGD:11038789 NCBI chr 6:27,800,060...27,849,170
Ensembl chr 6:27,798,835...27,848,689
JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 ISO mRNA:decreased expression:small intestine RGD PMID:19152228 RGD:2315573 NCBI chr32:11,443,778...11,517,674
Ensembl chr32:11,443,780...11,517,674
JBrowse link
G ACAN aggrecan treatment ISO RGD PMID:25821409 RGD:12879456 NCBI chr 3:51,995,100...52,031,812
Ensembl chr 3:51,969,779...52,031,544
JBrowse link
G ACE angiotensin I converting enzyme ISO RGD PMID:20213806 RGD:2325221 NCBI chr 9:11,497,182...11,516,362
Ensembl chr 9:11,497,182...11,516,358
JBrowse link
G ACSL1 acyl-CoA synthetase long chain family member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18988084 NCBI chr16:45,735,675...45,806,235
Ensembl chr16:45,735,703...45,804,970
JBrowse link
G ACSL4 acyl-CoA synthetase long chain family member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18988084 NCBI chr  X:82,864,506...82,943,984
Ensembl chr  X:82,866,823...82,916,789
JBrowse link
G ACSL5 acyl-CoA synthetase long chain family member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18988084 NCBI chr28:23,437,838...23,478,763
Ensembl chr28:23,440,387...23,478,762
JBrowse link
G ADAM10 ADAM metallopeptidase domain 10 ISO RGD PMID:23897050 RGD:13703039 NCBI chr30:23,605,724...23,732,038
Ensembl chr30:23,606,517...23,731,823
JBrowse link
G ADAM17 ADAM metallopeptidase domain 17 ISO RGD PMID:23897050 RGD:13703039 NCBI chr17:6,589,874...6,638,788
Ensembl chr17:6,589,878...6,638,731
JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing ISO protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:19026984 PMID:21681567 PMID:23326410 RGD:5685385 RGD:5686814 NCBI chr34:19,398,310...19,410,519
Ensembl chr34:19,354,825...19,409,844
JBrowse link
G ADK adenosine kinase ISO RGD PMID:11160636 RGD:6482663 NCBI chr 4:24,540,626...25,047,032
Ensembl chr 4:24,540,659...25,046,464
JBrowse link
G AHCY adenosylhomocysteinase ISO RGD PMID:11123369 RGD:1598898 NCBI chr24:23,410,553...23,423,494
Ensembl chr24:23,411,140...23,419,767
JBrowse link
G AHR aryl hydrocarbon receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:25194622 NCBI chr14:31,743,704...31,793,484
Ensembl chr14:31,686,170...31,791,444
JBrowse link
G AKT1 AKT serine/threonine kinase 1 treatment ISO RGD PMID:22391142 RGD:10041007 NCBI chr 8:72,317,399...72,335,686
Ensembl chr 8:72,317,869...72,335,193
JBrowse link
G ALB albumin ISO CTD Direct Evidence: marker/mechanism CTD PMID:20472598 NCBI chr13:62,133,747...62,169,349
Ensembl chr13:62,053,814...62,294,709
JBrowse link
G ALOX15 arachidonate 15-lipoxygenase ISO RGD PMID:19675173 RGD:5509599 NCBI chr 5:31,883,544...31,891,357
Ensembl chr 5:31,882,501...32,038,119
JBrowse link
G ANXA1 annexin A1 ISO RGD PMID:10403283 PMID:23267026 RGD:2306928 RGD:7421573 NCBI chr 1:84,744,159...84,763,011
Ensembl chr 1:84,744,163...84,763,011
JBrowse link
G ANXA2 annexin A2 ameliorates ISO RGD PMID:24819400 RGD:150519886 NCBI chr30:25,176,845...25,210,244
Ensembl chr30:25,115,842...25,218,281
JBrowse link
G AOC3 amine oxidase copper containing 3 ISO RGD PMID:16947396 RGD:2313925 NCBI chr 9:20,158,581...20,179,773
Ensembl chr 9:20,157,410...20,241,376
JBrowse link
G APOA4 apolipoprotein A4 ISO protein:decreased expression:blood serum (rat) RGD PMID:10892728 RGD:5685694 NCBI chr 5:16,751,588...16,754,215
Ensembl chr 5:16,751,799...16,754,837
JBrowse link
G ARRB1 arrestin beta 1 ISO protein:increased expression:knee, synoviocyte (rat) RGD PMID:20965243 RGD:5509895 NCBI chr21:23,261,020...23,304,448
Ensembl chr21:23,235,711...23,297,786
JBrowse link
G ARRB2 arrestin beta 2 ISO protein:increased expression:knee, synoviocyte (rat) RGD PMID:20965243 RGD:5509895 NCBI chr 5:31,831,208...31,838,875
Ensembl chr 5:31,829,864...31,839,454
JBrowse link
G ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase ISO RGD PMID:17408934 RGD:5144054 NCBI chr37:22,420,645...22,446,769
Ensembl chr37:22,420,603...22,446,697
JBrowse link
G B9D2 B9 domain containing 2 ISO RGD PMID:29763498 RGD:15036801 NCBI chr 1:112,621,832...112,627,726
Ensembl chr 1:112,621,633...112,643,885
JBrowse link
G BAX BCL2 associated X, apoptosis regulator treatment ISO RGD PMID:21199477 PMID:22978269 RGD:10054249 RGD:10054498 NCBI chr 1:107,423,388...107,426,464
Ensembl chr 1:107,422,424...107,426,464
JBrowse link
G BCL2 BCL2 apoptosis regulator treatment ISO RGD PMID:21199477 PMID:22978269 RGD:10054249 RGD:10054498 NCBI chr 1:13,733,849...13,900,653
Ensembl chr 1:13,731,406...13,900,658
JBrowse link
G BDKRB1 bradykinin receptor B1 ISO RGD PMID:15001555 RGD:1625760 NCBI chr 8:65,017,655...65,028,899 JBrowse link
G BGLAP bone gamma-carboxyglutamate protein ISO protein:decreased expression:serum RGD PMID:21406003 RGD:6483549 NCBI chr 7:41,630,092...41,630,976
Ensembl chr 7:41,630,098...41,665,791
JBrowse link
G BTK Bruton tyrosine kinase treatment ISO RGD PMID:22228807 PMID:32083858 RGD:11040701 RGD:151665122 NCBI chr  X:75,270,952...75,302,663
Ensembl chr  X:75,270,979...75,302,562
JBrowse link
G C3 complement C3 treatment ISO RGD PMID:7347767 PMID:20051658 RGD:11041098 RGD:7411688 NCBI chr20:53,566,226...53,598,365
Ensembl chr20:53,566,261...53,598,761
JBrowse link
G C5 complement C5 ISO RGD PMID:12355496 PMID:20975959 RGD:1600637 RGD:5130175 NCBI chr11:73,953,727...74,029,919
Ensembl chr11:73,953,727...74,029,851
JBrowse link
G CABIN1 calcineurin binding protein 1 ISO RGD PMID:22275266 RGD:10054391 NCBI chr26:28,366,264...28,517,570
Ensembl chr26:28,366,265...28,517,656
JBrowse link
G CAT catalase ISO CTD Direct Evidence: marker/mechanism CTD PMID:22450443 NCBI chr18:33,383,005...33,422,447
Ensembl chr18:33,383,005...33,422,447
JBrowse link
G CBL Cbl proto-oncogene treatment ISO RGD PMID:16984225 RGD:2306289 NCBI chr 5:14,600,409...14,676,974
Ensembl chr 5:14,607,013...14,676,956
JBrowse link
G CBLB Cbl proto-oncogene B ISO RGD PMID:16984225 RGD:2306289 NCBI chr33:11,255,453...11,665,755
Ensembl chr33:11,199,863...11,530,810
JBrowse link
G CCL2 C-C motif chemokine ligand 2 treatment ISO mRNA, protein:increased expression:synovium RGD PMID:17052673 PMID:18292571 PMID:18726678 PMID:24583103 RGD:11526142 RGD:2307008 RGD:2307052 RGD:2307143 NCBI chr 9:39,008,187...39,009,932 JBrowse link
G CCL5 C-C motif chemokine ligand 5 ISO mRNA, protein:increased expression:synovium, monocytes RGD PMID:9637726 PMID:17052673 RGD:2307143 RGD:4889940 NCBI chr 9:37,817,409...37,823,852
Ensembl chr 9:37,817,305...37,823,852
JBrowse link
G CCL7 C-C motif chemokine ligand 7 onset ISO RGD PMID:17178563 RGD:6483780 NCBI chr 9:38,994,638...38,996,103
Ensembl chr 9:38,993,911...39,010,483
JBrowse link
G CCN1 cellular communication network factor 1 ameliorates ISO RGD PMID:27653023 RGD:150429754 NCBI chr 6:62,443,285...62,446,246
Ensembl chr 6:62,443,675...62,445,994
JBrowse link
G CCR1 chemokine (C-C motif) receptor 1 ISO RGD PMID:14674010 PMID:18608173 RGD:1582346 RGD:5688144 NCBI chr20:42,421,356...42,427,177
Ensembl chr20:42,421,356...42,426,958
JBrowse link
G CCR2 C-C motif chemokine receptor 2 ISO RGD PMID:16320322 RGD:4144893 NCBI chr20:42,305,344...42,313,258
Ensembl chr20:42,307,580...42,308,698
JBrowse link
G CCR5 C-C motif chemokine receptor 5 treatment ISO mRNA:increased expression:ankle (rat) RGD PMID:14674010 PMID:22289897 RGD:1582346 RGD:5687744 NCBI chr20:42,293,288...42,297,952
Ensembl chr20:42,294,996...42,297,952
JBrowse link
G CD28 CD28 molecule ISO RGD PMID:18601859 RGD:2307202 NCBI chr37:12,503,849...12,536,362
Ensembl chr37:12,503,811...12,532,854
JBrowse link
G CD4 CD4 molecule treatment ISO RGD PMID:12010568 PMID:15479897 RGD:10058957 RGD:10058960 NCBI chr27:38,204,003...38,250,771
Ensembl chr27:38,204,003...38,250,771
JBrowse link
G CD40 CD40 molecule ISO RGD PMID:20435931 RGD:5490544 NCBI chr24:33,352,992...33,383,488
Ensembl chr24:33,372,930...33,383,301
JBrowse link
G CD40LG CD40 ligand treatment ISO protein:increased expression:plasma (rat) RGD PMID:7689748 PMID:22611405 PMID:27218142 RGD:11344958 RGD:11352298 RGD:11352696 NCBI chr  X:107,001,421...107,023,007
Ensembl chr  X:107,010,890...107,023,006
JBrowse link
G CD44 CD44 molecule ISO protein:increased expression:joint, macrophage, lymphocyte RGD PMID:8639178 RGD:2289388 NCBI chr18:32,735,493...32,826,483
Ensembl chr18:32,737,907...32,827,107
JBrowse link
G CD59 CD59 molecule ISO RGD PMID:14519760 RGD:1600483 NCBI chr18:33,977,433...33,999,145
Ensembl chr18:33,977,480...33,998,329
JBrowse link
G CD69 CD69 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:12882836 NCBI chr27:36,197,202...36,205,045
Ensembl chr27:36,197,175...36,204,597
JBrowse link
G CD80 CD80 molecule ISO RGD PMID:22004797 RGD:6902903 NCBI chr33:23,177,136...23,208,421
Ensembl chr33:23,177,138...23,201,380
JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A treatment ISO RGD PMID:10395320 RGD:8552686 NCBI chr11:41,223,316...41,226,056
Ensembl chr11:41,223,315...41,264,379
JBrowse link
G CFH complement factor H ISO RGD PMID:19828624 RGD:5684557 NCBI chr38:2,878,677...2,956,226 JBrowse link
G COL2A1 collagen type II alpha 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:16200597 PMID:21188452 PMID:23326410 PMID:24709313 PMID:25194622 More... NCBI chr27:6,756,994...6,787,733
Ensembl chr27:6,756,994...6,787,733
JBrowse link
G CP ceruloplasmin ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:19205849 PMID:19330884 RGD:2314686 NCBI chr23:43,969,297...44,033,226
Ensembl chr23:43,969,435...44,030,369
JBrowse link
G CPOX coproporphyrinogen oxidase ISO protein:decreased activity:liver (rat) RGD PMID:9173682 RGD:1600958 NCBI chr33:5,446,022...5,459,152
Ensembl chr33:5,447,414...5,459,461
JBrowse link
G CRHR1 corticotropin releasing hormone receptor 1 ISO RGD PMID:17550594 RGD:1626231 NCBI chr 9:9,708,696...9,763,281
Ensembl chr 9:9,714,204...9,763,402
JBrowse link
G CRP C-reactive protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:19330884 NCBI chr38:22,396,787...22,398,180
Ensembl chr38:22,396,263...22,399,166
JBrowse link
G CRSP-3 calcitonin receptor-stimulating peptide 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16690336 NCBI chr21:37,676,841...37,680,643
Ensembl chr21:37,676,841...37,680,645
JBrowse link
G CSF1 colony stimulating factor 1 ISO protein:increased expression:dorsal root ganglion RGD PMID:32510872 RGD:127338469 NCBI chr 6:42,028,454...42,047,028
Ensembl chr 6:42,034,149...42,049,371
JBrowse link
G CSF1R colony stimulating factor 1 receptor treatment ISO RGD PMID:18434589 RGD:151665814 NCBI chr 4:58,980,699...59,010,683
Ensembl chr 4:58,980,788...59,010,510
JBrowse link
G CSF3 colony stimulating factor 3 treatment ISO RGD PMID:12742377 RGD:11039465 NCBI chr 9:22,529,643...22,532,326
Ensembl chr 9:22,530,698...22,533,108
JBrowse link
G CSK C-terminal Src kinase ISO RGD PMID:10411542 RGD:5134371 NCBI chr30:37,851,269...37,870,382
Ensembl chr30:37,852,046...37,870,378
JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 treatment ISO RGD PMID:7543497 PMID:22354915 RGD:7204500 RGD:7204519 NCBI chr37:12,647,712...12,653,874
Ensembl chr37:12,634,563...12,653,874
JBrowse link
G CTSB cathepsin B ISO mRNA:increased expression:knee joint, synovium (rat) RGD PMID:17195213 RGD:2315521 NCBI chr25:26,048,237...26,056,570
Ensembl chr25:26,048,253...26,055,801
JBrowse link
G CTSK cathepsin K ISO mRNA:increased expression:synovium, bone marrow RGD PMID:15353610 RGD:1601025 NCBI chr17:59,928,725...59,938,293
Ensembl chr17:59,929,287...59,938,507
JBrowse link
G CTSS cathepsin S ISO RGD PMID:21439785 RGD:5686915 NCBI chr17:59,893,840...59,910,878
Ensembl chr17:59,893,840...59,910,849
JBrowse link
G CX3CL1 C-X3-C motif chemokine ligand 1 ISO RGD PMID:11465708 RGD:4892002 NCBI chr 2:59,022,794...59,032,095
Ensembl chr 2:59,022,794...59,032,095
JBrowse link
G CX3CR1 C-X3-C motif chemokine receptor 1 ISO protein:increased expression:spinal cord RGD PMID:11465708 PMID:17123734 RGD:4891969 RGD:4892002 NCBI chr23:8,937,069...8,954,738
Ensembl chr23:8,938,906...8,952,808
JBrowse link
G DDR2 discoidin domain receptor tyrosine kinase 2 ameliorates ISO RGD PMID:24819400 RGD:150519886 NCBI chr38:20,002,984...20,152,930
Ensembl chr38:20,008,057...20,152,275
JBrowse link
G DHODH dihydroorotate dehydrogenase (quinone) ISO RGD PMID:15182735 RGD:2316231 NCBI chr 5:77,756,411...77,766,207
Ensembl chr 5:77,756,407...77,774,090
JBrowse link
G DNMT1 DNA methyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25194984 NCBI chr20:50,872,213...50,928,352
Ensembl chr20:50,879,527...50,928,029
JBrowse link
G DRD1 dopamine receptor D1 treatment ISO mRNA:increased expression:corpus striatum (rat) RGD PMID:23762129 RGD:7248592 NCBI chr 4:37,550,454...37,554,641
Ensembl chr 4:37,549,708...37,553,287
JBrowse link
G DRD2 dopamine receptor D2 treatment ISO mRNA:increased expression:corpus striatum (rat) RGD PMID:23762129 RGD:7248592 NCBI chr 5:19,732,842...19,795,241
Ensembl chr 5:19,732,836...19,795,241
JBrowse link
G EDN1 endothelin 1 ISO mRNA:increased expression:inguinal lymph node (mouse) RGD PMID:22249931 RGD:8661695 NCBI chr35:11,808,892...11,815,383
Ensembl chr35:11,808,892...11,815,383
JBrowse link
G EGFR epidermal growth factor receptor ISO CTD Direct Evidence: therapeutic CTD PMID:7589090 NCBI chr18:5,983,669...6,044,092
Ensembl chr18:5,982,770...6,042,631
JBrowse link
G ESR1 estrogen receptor 1 treatment ISO associated with Osteoporosis RGD PMID:20112355 RGD:10045851 NCBI chr 1:42,081,952...42,368,544
Ensembl chr 1:42,081,969...42,368,544
JBrowse link
G ESR2 estrogen receptor 2 ISO RGD PMID:16269464 RGD:5508854 NCBI chr 8:38,645,917...38,715,347
Ensembl chr 8:38,645,430...38,702,691
JBrowse link
G F2 coagulation factor II, thrombin ISO RGD PMID:21436072 RGD:5147764 NCBI chr18:42,782,744...42,799,531
Ensembl chr18:42,782,751...42,799,459
JBrowse link
G F2R coagulation factor II thrombin receptor severity ISO RGD PMID:19674841 RGD:7387269 NCBI chr 3:29,870,159...29,889,837
Ensembl chr 3:29,872,155...29,889,687
JBrowse link
G F2RL1 F2R like trypsin receptor 1 ISO RGD PMID:12511586 RGD:735010 NCBI chr 3:29,801,119...29,810,006
Ensembl chr 3:29,800,211...29,810,180
JBrowse link
G FASLG Fas ligand treatment ISO RGD PMID:22354915 RGD:7204500 NCBI chr 7:26,335,837...26,344,224
Ensembl chr 7:26,335,846...26,344,224
JBrowse link
G FCGR1A Fc fragment of IgG receptor Ia ISO protein:increased expression:dorsal root ganglion
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:12875993 PMID:16670289 PMID:32510872 RGD:127338469 RGD:9685708 NCBI chr17:59,073,139...59,102,023
Ensembl chr17:59,092,933...59,102,015
JBrowse link
G FCGR2B Fc fragment of IgG receptor IIb ISO RGD PMID:23341540 RGD:11344930 NCBI chr38:20,980,777...20,994,403 JBrowse link
G FGF8 fibroblast growth factor 8 ISO RGD PMID:18699993 RGD:2314157 NCBI chr28:14,362,407...14,367,109
Ensembl chr28:14,362,109...14,367,468
JBrowse link
G FGFR1 fibroblast growth factor receptor 1 ISO RGD PMID:22833219 RGD:10402072 NCBI chr16:27,029,902...27,080,514
Ensembl chr16:27,031,588...27,078,261
JBrowse link
G FLT1 fms related receptor tyrosine kinase 1 ISO RGD PMID:19180491 RGD:6483591 NCBI chr25:11,231,958...11,410,379
Ensembl chr25:11,231,737...11,407,621
JBrowse link
G FLT3 fms related receptor tyrosine kinase 3 ISO RGD PMID:10857786 RGD:61066 NCBI chr25:11,551,372...11,670,891
Ensembl chr25:11,581,206...11,692,284
JBrowse link
G FOXP3 forkhead box P3 treatment ISO mRNA,protein:decreased expression:lung RGD PMID:23643080 PMID:29264841 RGD:38549364 RGD:38599003 NCBI chr  X:42,331,229...42,362,841
Ensembl chr  X:42,344,108...42,350,758
JBrowse link
G GJA1 gap junction protein alpha 1 ISO RGD PMID:23165424 RGD:7207259 NCBI chr 1:60,941,772...60,944,694
Ensembl chr 1:60,929,097...60,942,936
JBrowse link
G GLI1 GLI family zinc finger 1 treatment ISO RGD PMID:25821409 RGD:12879456 NCBI chr10:1,565,306...1,575,971
Ensembl chr10:1,565,244...1,575,982
JBrowse link
G GPI glucose-6-phosphate isomerase ISO RGD PMID:23911657 RGD:11051957 NCBI chr 1:117,922,380...117,948,325
Ensembl chr 1:117,922,635...117,948,316
JBrowse link
G GRK2 G protein-coupled receptor kinase 2 treatment
disease_progression
ISO protein:increased expression:aorta (rat)
protein:altered expression:T cell (rat)
RGD PMID:28349925 PMID:28631356 PMID:28653218 RGD:13513975 RGD:13513976 RGD:13513979 NCBI chr18:50,148,566...50,167,422
Ensembl chr18:50,148,598...50,167,428
JBrowse link
G GRN granulin precursor ISO RGD PMID:21393509 RGD:5509782 NCBI chr 9:19,077,430...19,085,443
Ensembl chr 9:19,077,427...19,082,268
JBrowse link
G GSK3B glycogen synthase kinase 3 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:16713974 NCBI chr33:23,458,369...23,659,878
Ensembl chr33:23,463,767...23,659,666
JBrowse link
G GUSB glucuronidase beta treatment ISO RGD PMID:827200 RGD:42724460 NCBI chr 6:730,345...743,916
Ensembl chr 6:730,358...779,424
JBrowse link
G HAVCR2 hepatitis A virus cellular receptor 2 ISO mRNA,protein:altered expression:bone: RGD PMID:25264706 RGD:9686117 NCBI chr 4:53,018,990...53,032,035
Ensembl chr 4:53,012,234...53,033,393
JBrowse link
G HDAC6 histone deacetylase 6 treatment ISO RGD PMID:23541634 RGD:9681550 NCBI chr  X:42,004,268...42,024,726
Ensembl chr  X:42,004,591...42,024,427
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha treatment ISO RGD PMID:21679445 RGD:8693318 NCBI chr 8:36,614,045...36,656,692
Ensembl chr 8:36,614,045...36,656,692
JBrowse link
G HLA-DRB1 MHC class II DLA DRB1 beta chain ISO RGD PMID:19950279 PMID:21665435 RGD:5147558 RGD:5147586 NCBI chr12:2,151,409...2,164,564 JBrowse link
G HMGB1 high mobility group box 1 ISO protein:altered localization:cytoplasm, extracellular matrix RGD PMID:12384917 RGD:728698 NCBI chr25:9,431,223...9,558,167
Ensembl chr25:9,431,218...9,558,165
JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase ISO RGD PMID:17119970 RGD:5508468 NCBI chr 3:30,970,037...30,988,987
Ensembl chr 3:30,970,037...30,990,294
JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 ISO RGD PMID:10882416 PMID:15529360 RGD:12910542 RGD:1624244 NCBI chr37:7,010,421...7,025,912 JBrowse link
G IFNG interferon gamma ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:7774621 PMID:12412757 PMID:19203382 PMID:22450443 RGD:10755750 RGD:2311498 NCBI chr10:10,406,866...10,411,698
Ensembl chr10:10,406,867...10,411,698
JBrowse link
G IGF1 insulin like growth factor 1 ISO protein:decreased expression:plasma RGD PMID:19246225 RGD:2306697 NCBI chr15:41,203,320...41,275,964
Ensembl chr15:41,202,518...41,275,794
JBrowse link
G IGFBP3 insulin like growth factor binding protein 3 ISO mRNA, protein:increased expression:kidney, serum RGD PMID:14642797 RGD:10402760 NCBI chr16:1,021,855...1,027,604
Ensembl chr16:1,021,972...1,026,392
JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta treatment ISO RGD PMID:19652024 PMID:21087862 RGD:7495772 RGD:7495778 NCBI chr16:23,359,551...23,419,114
Ensembl chr16:23,359,813...23,419,075
JBrowse link
G IKBKG inhibitor of nuclear factor kappa B kinase regulatory subunit gamma treatment ISO RGD PMID:16684367 RGD:12791276 NCBI chr  X:122,232,052...122,253,499
Ensembl chr  X:122,235,878...122,250,562
JBrowse link
G IL10 interleukin 10 treatment ISO CTD Direct Evidence: marker/mechanism|therapeutic
protein:decreased expression:serum:
RGD
CTD
PMID:15270736 PMID:19169271 PMID:19193354 PMID:20974942 PMID:22052031 More... RGD:1626677 RGD:2311059 RGD:7193038 RGD:7364838 RGD:8662976 NCBI chr 7:5,933,285...5,937,057
Ensembl chr 7:5,933,285...5,937,057
JBrowse link
G IL13 interleukin 13 treatment ISO CTD Direct Evidence: therapeutic CTD
RGD
PMID:10444273 PMID:11860705 PMID:17665443 RGD:4889497 RGD:8549606 NCBI chr11:20,957,870...20,961,391
Ensembl chr11:20,958,464...20,961,388
JBrowse link
G IL15 interleukin 15 ISO RGD PMID:20188418 RGD:5000761 NCBI chr19:1,339,607...1,364,762
Ensembl chr19:1,339,967...1,364,762
JBrowse link
G IL17A interleukin 17A treatment ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:serum (rat)
RGD
CTD
PMID:20925596 PMID:20974942 PMID:21194185 PMID:23377547 RGD:4781444 RGD:9068936 RGD:9130803 NCBI chr12:19,854,129...19,862,521
Ensembl chr12:19,854,129...19,862,513
JBrowse link
G IL18 interleukin 18 disease_progression ISO RGD PMID:15147345 PMID:19096963 RGD:4889415 RGD:4889503 NCBI chr 5:20,972,742...20,995,327
Ensembl chr 5:20,972,871...20,995,348
JBrowse link
G IL1A interleukin 1 alpha ISO protein:increased expression:serum: RGD PMID:19169271 PMID:20379758 RGD:6907373 RGD:8662976 NCBI chr17:36,969,581...36,979,445
Ensembl chr17:36,970,573...36,979,435
JBrowse link
G IL1B interleukin 1 beta treatment ISO protein:increased expression:serum (rat)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:19330884 PMID:20131233 PMID:20974942 PMID:21557995 PMID:22450443 More... RGD:10755447 RGD:13792834 RGD:7175317 RGD:7193038 NCBI chr17:37,019,329...37,033,388
Ensembl chr17:37,019,329...37,024,458
JBrowse link
G IL1RL1 interleukin 1 receptor like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20472598 NCBI chr10:40,658,191...40,732,097
Ensembl chr10:40,659,041...40,677,357
JBrowse link
G IL1RN interleukin 1 receptor antagonist treatment ISO mRNA:increased expression:popliteal lymph node (rat)
rat model treated with human protein
mouse model treated with human protein
human gene in a rat model
RGD PMID:10921508 PMID:12727108 PMID:15270736 PMID:22267332 PMID:23006786 RGD:1626677 RGD:6907376 RGD:8549801 RGD:8551741 RGD:8551745 NCBI chr17:37,236,690...37,250,424
Ensembl chr17:37,212,751...37,249,329
JBrowse link
G IL2 interleukin 2 treatment ISO protein:increased expression:serum: RGD PMID:2492102 PMID:19169271 RGD:10047055 RGD:8662976 NCBI chr19:17,750,780...17,756,394
Ensembl chr19:17,750,780...17,756,394
JBrowse link
G IL20 interleukin 20 ISO RGD PMID:20722035 RGD:5147393 NCBI chr 7:6,019,879...6,022,707
Ensembl chr 7:6,019,442...6,023,219
JBrowse link
G IL2RA interleukin 2 receptor subunit alpha ISO RGD PMID:17928458 RGD:2325988 NCBI chr 2:29,892,130...29,948,926
Ensembl chr 2:29,894,125...29,944,643
JBrowse link
G IL33 interleukin 33 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20472598 NCBI chr11:27,219,878...27,256,723
Ensembl chr11:27,219,878...27,256,721
JBrowse link
G IL4 interleukin 4 treatment ISO CTD Direct Evidence: therapeutic RGD
CTD
PMID:10444273 PMID:16869003 PMID:23140046 PMID:23972727 RGD:10402790 RGD:2317300 RGD:7193038 NCBI chr11:20,972,693...20,981,539
Ensembl chr11:20,972,690...20,981,534
JBrowse link
G IL6 interleukin 6 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:8607900 PMID:10381487 PMID:20131233 PMID:20974942 PMID:22450443 More... RGD:10755447 RGD:11049551 RGD:11049553 RGD:11060267 NCBI chr14:36,474,268...36,478,519
Ensembl chr14:36,473,394...36,478,519
JBrowse link
G IL6ST interleukin 6 cytokine family signal transducer ISO RGD PMID:20626857 RGD:5509945 NCBI chr 2:43,214,050...43,273,014
Ensembl chr 2:43,214,050...43,248,124
JBrowse link
G ITGA4 integrin subunit alpha 4 treatment ISO RGD PMID:12969328 RGD:9698440 NCBI chr36:24,670,464...24,686,719
Ensembl chr36:24,653,408...24,729,057
JBrowse link
G ITGB2 integrin subunit beta 2 ISO RGD PMID:8881759 RGD:6482229 NCBI chr31:38,520,733...38,547,003
Ensembl chr31:38,521,103...38,547,018
JBrowse link
G ITGB3 integrin subunit beta 3 ISO protein:increased expression:endothelial cell RGD PMID:16869003 RGD:2317300 NCBI chr 9:9,179,667...9,231,061
Ensembl chr 9:9,182,562...9,231,451
JBrowse link
G JAG1 jagged canonical Notch ligand 1 ISO RGD PMID:19265135 RGD:6482234 NCBI chr24:11,656,926...11,693,146
Ensembl chr24:11,657,416...11,692,199
JBrowse link
G JAK1 Janus kinase 1 treatment ISO RGD PMID:29452839 RGD:19165139 NCBI chr 5:45,251,653...45,408,571
Ensembl chr 5:45,251,653...45,408,571
JBrowse link
G JAK2 Janus kinase 2 treatment ISO RGD PMID:22339472 PMID:22800927 PMID:23711144 RGD:10403066 RGD:10403074 RGD:10403081 NCBI chr 1:93,321,055...93,438,898
Ensembl chr 1:93,142,635...93,435,997
JBrowse link
G JAK3 Janus kinase 3 treatment ISO RGD PMID:18234077 PMID:21434883 PMID:25762693 RGD:11533938 RGD:11533942 RGD:11533944 NCBI chr20:45,051,135...45,068,445
Ensembl chr20:45,050,526...45,072,805
JBrowse link
G KCNN4 potassium calcium-activated channel subfamily N member 4 ameliorates ISO RGD PMID:25131209 RGD:150521609 NCBI chr 1:111,391,464...111,407,612
Ensembl chr 1:111,391,159...111,407,701
JBrowse link
G KLKB1 kallikrein B1 ISO RGD PMID:9783057 PMID:22739815 RGD:7297047 RGD:7327138 NCBI chr16:44,492,735...44,517,854
Ensembl chr16:44,469,632...44,540,292
JBrowse link
G KNG1 kininogen 1 ISO peptidoglycan-polysaccharide-induced arthritis in Lewis rats RGD PMID:1996642 PMID:9214434 RGD:11059895 RGD:1600547 NCBI chr34:19,288,629...19,318,096
Ensembl chr34:19,287,109...19,318,081
JBrowse link
G KYAT1 kynurenine aminotransferase 1 ISO RGD PMID:16984225 RGD:2306289 NCBI chr 9:54,760,212...54,796,996
Ensembl chr 9:54,760,276...54,796,848
JBrowse link
G LEP leptin ISO CTD Direct Evidence: marker/mechanism CTD PMID:15142272 NCBI chr14:8,115,396...8,130,946
Ensembl chr14:8,116,122...8,131,395
JBrowse link
G LGALS3 galectin 3 ISO RGD PMID:16507131 RGD:1625684 NCBI chr 8:30,977,438...30,994,711
Ensembl chr 8:30,983,633...30,994,705
JBrowse link
G LOC403934 cell division cycle 42 ISO protein:increased activation:bone marrow, macrophage RGD PMID:21266780 RGD:5688271 NCBI chr 2:77,153,276...77,169,947
Ensembl chr 2:77,153,095...77,199,211
JBrowse link
G LOC477699 alpha-2-macroglobulin ISO protein:increased expression:serum RGD PMID:6163339 RGD:10046032 NCBI chr27:36,654,328...36,695,775 JBrowse link
G LOC609365 CD46 molecule, complement regulatory protein-like ISO RGD PMID:21852528 RGD:6483461 NCBI chr 7:6,602,762...6,646,561 JBrowse link
G MAP3K5 mitogen-activated protein kinase kinase kinase 5 ISO RGD PMID:16331767 RGD:10412332 NCBI chr 1:29,107,813...29,306,437
Ensembl chr 1:29,108,591...29,306,503
JBrowse link
G MIF macrophage migration inhibitory factor ISO RGD PMID:10765927 RGD:1642012
G MIR152 microRNA mir-152 ISO CTD Direct Evidence: marker/mechanism
miRNA:decreased exression:synovial membrane of synovial joint
CTD
RGD
PMID:25194984 RGD:21066343 NCBI chr 9:24,335,161...24,335,219
Ensembl chr 9:24,335,146...24,335,225
JBrowse link
G MIR26A-1 microRNA mir-26a-1 ISO CTD Direct Evidence: therapeutic CTD PMID:24423102 NCBI chr23:7,747,073...7,747,133
Ensembl chr23:7,747,064...7,747,140
JBrowse link
G MMP1 matrix metallopeptidase 1 ISO RGD PMID:21108488 PMID:21288455 PMID:24011916 RGD:7207362 RGD:7207365 RGD:8549748 NCBI chr 5:28,978,385...28,986,644
Ensembl chr 5:28,978,473...28,986,648
JBrowse link
G MMP13 matrix metallopeptidase 13 treatment ISO RGD PMID:11435459 PMID:24244039 RGD:1582329 RGD:8694124 NCBI chr 5:28,793,568...28,864,832
Ensembl chr 5:28,850,522...28,864,121
JBrowse link
G MMP3 matrix metallopeptidase 3 (stromelysin 1, progelatinase) treatment ISO mRNA:increased expression:ankle joint
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:20703013 PMID:20974942 PMID:21679445 PMID:24011916 PMID:24244039 RGD:7241231 RGD:8549748 RGD:8693318 RGD:8694124 NCBI chr 5:28,949,631...28,957,915
Ensembl chr 5:28,949,631...28,958,222
JBrowse link
G MMP9 matrix metallopeptidase 9 ISO protein:increased expression:cartilage, serum, synovial fluid RGD PMID:17463159 RGD:1642035 NCBI chr24:33,274,260...33,281,116
Ensembl chr24:33,274,268...33,281,293
JBrowse link
G MPO myeloperoxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:22450443 NCBI chr 9:32,927,483...32,938,007
Ensembl chr 9:32,927,483...32,937,820
JBrowse link
G MT-ATP8 mitochondrially encoded ATP synthase membrane subunit 8 susceptibility ISO DNA:transversion: :m.7778G>T (mouse) RGD PMID:19759059 RGD:5490297 NCBI chr MT:7,803...8,006
Ensembl chr MT:7,803...8,006
JBrowse link
G MTOR mechanistic target of rapamycin kinase treatment ISO RGD PMID:22391142 RGD:10041007 NCBI chr 2:84,818,893...84,939,283
Ensembl chr 2:84,787,708...84,939,114
JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor ISO RGD PMID:20131263 RGD:8552884 NCBI chr23:7,901,578...7,905,274
Ensembl chr23:7,901,250...7,904,534
JBrowse link
G MYOD1 myogenic differentiation 1 treatment ISO RGD PMID:23781298 RGD:9686078 NCBI chr21:40,257,792...40,260,461
Ensembl chr21:40,258,027...40,259,712
JBrowse link
G MYOG myogenin treatment ISO RGD PMID:23781298 RGD:9686078 NCBI chr 7:112,116...114,604
Ensembl chr 7:112,034...113,892
JBrowse link
G NCF1 neutrophil cytosolic factor 1 severity ISO DNA:missense mutations:cds:p.M106V, p.M153T (rat) RGD PMID:12461526 RGD:628543 NCBI chr 6:5,702,222...5,719,515
Ensembl chr 6:5,605,694...5,719,458
JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 ISO RGD PMID:20131263 PMID:21424514 RGD:5508728 RGD:8552884 NCBI chr 2:64,636,850...64,667,232
Ensembl chr 2:64,635,519...64,667,232
JBrowse link
G NOS2 nitric oxide synthase 2 ISO protein:increased expression:ankle joint (mouse) RGD PMID:12826065 PMID:21880869 RGD:1358527 RGD:5509060 NCBI chr 9:42,171,821...42,210,217
Ensembl chr 9:42,171,821...42,208,588
JBrowse link
G NOS3 nitric oxide synthase 3 treatment ISO RGD PMID:29337196 RGD:13504725 NCBI chr16:15,054,196...15,072,454
Ensembl chr16:15,011,344...15,072,277
JBrowse link
G NPSR1 neuropeptide S receptor 1 treatment ISO RGD PMID:24884567 RGD:9831205 NCBI chr14:46,465,169...46,610,256
Ensembl chr14:46,466,544...46,609,477
JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 severity ISO RGD PMID:16905546 RGD:11073695 NCBI chr 5:79,979,593...79,990,875
Ensembl chr 5:79,978,865...79,989,860
JBrowse link
G NR1H2 nuclear receptor subfamily 1 group H member 2 ISO RGD PMID:21859686 RGD:6480864 NCBI chr 1:106,332,691...106,339,168
Ensembl chr 1:106,332,798...106,339,135
JBrowse link
G NR1H3 nuclear receptor subfamily 1 group H member 3 ISO RGD PMID:21859686 RGD:6480864 NCBI chr18:42,333,173...42,346,152
Ensembl chr18:42,333,202...42,341,236
JBrowse link
G NRAS NRAS proto-oncogene, GTPase ISO RGD PMID:18706093 RGD:2300006 NCBI chr17:52,411,733...52,418,788
Ensembl chr17:52,411,733...52,418,788
JBrowse link
G NTS neurotensin ISO RGD PMID:8518953 RGD:9743903 NCBI chr15:27,361,002...27,372,232
Ensembl chr15:27,361,002...27,372,232
JBrowse link
G P2RY12 purinergic receptor P2Y12 ISO RGD PMID:22028806 RGD:6480518 NCBI chr23:45,908,574...45,954,675
Ensembl chr23:45,909,485...45,910,526
JBrowse link
G PAM peptidylglycine alpha-amidating monooxygenase ISO RGD PMID:17138865 RGD:6483527 NCBI chr 3:8,141,508...8,312,081
Ensembl chr 3:8,142,061...8,290,477
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 severity ISO RGD PMID:16356201 RGD:5684009 NCBI chr 7:38,503,072...38,542,556
Ensembl chr 7:38,503,067...38,542,127
JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 severity ISO protein:increased expression:knee joint, blood vessels (mouse) RGD PMID:14613294 PMID:21982514 PMID:22548760 RGD:6484738 RGD:6771177 RGD:6771222 NCBI chr 9:12,166,124...12,219,553
Ensembl chr 9:12,166,775...12,219,778
JBrowse link
G PGF placental growth factor ISO RGD PMID:19180491 RGD:6483591 NCBI chr 8:48,059,554...48,110,534
Ensembl chr 8:48,059,552...48,075,170
JBrowse link
G PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta ISO RGD PMID:18412166 RGD:6482696 NCBI chr 5:62,884,596...62,936,882
Ensembl chr 5:62,909,009...62,935,971
JBrowse link
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma ISO RGD PMID:18412166 PMID:20374644 RGD:6482684 RGD:6482696 NCBI chr18:13,576,966...13,611,748
Ensembl chr18:13,570,999...13,611,141
JBrowse link
G PLAU plasminogen activator, urokinase ISO RGD PMID:20973954 RGD:6483801 NCBI chr 4:24,329,139...24,333,893
Ensembl chr 4:24,328,925...24,334,851
JBrowse link
G PTCH1 patched 1 treatment ISO RGD PMID:25821409 RGD:12879456 NCBI chr 1:71,246,750...71,309,036
Ensembl chr 1:71,238,195...71,305,662
JBrowse link
G PTGER4 prostaglandin E receptor 4 disease_progression
treatment
ISO mRNA:increased expression:tarsal joint, synovium (rat)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:11207665 PMID:18287210 PMID:20423341 RGD:10003041 RGD:10003052 RGD:10043377 NCBI chr 4:68,663,362...68,676,241
Ensembl chr 4:68,663,364...68,676,358
JBrowse link
G PTGES prostaglandin E synthase ISO mRNA, protein:increased expression:paw RGD PMID:12707354 RGD:2300108 NCBI chr 9:54,071,472...54,082,232
Ensembl chr 9:54,071,472...54,082,232
JBrowse link
G PTGES3 prostaglandin E synthase 3 ISO mRNA:increased expression:paw (rat) RGD PMID:12707354 RGD:2300108 NCBI chr10:885,744...903,814
Ensembl chr10:870,392...909,161
JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO mRNA, protein:increased expression:synovium RGD PMID:22289897 RGD:5687744 NCBI chr 9:60,195,118...60,216,847
Ensembl chr 9:60,195,124...60,216,819
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO mRNA, protein:increased expression:synovium
protein:increased expression:autopod joint
RGD PMID:18758904 PMID:21765105 PMID:22289897 RGD:2300221 RGD:5508310 RGD:5687744 NCBI chr 7:19,668,079...19,674,903
Ensembl chr 7:19,668,082...19,674,903
JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 ISO protein:increased expression:metatarsophalangeal joint, mononuclear cell (rat) RGD PMID:24998229 RGD:11532752 NCBI chr17:51,623,628...51,683,039
Ensembl chr17:51,623,623...51,682,858
JBrowse link
G RAG2 recombination activating 2 ISO CTD Direct Evidence: therapeutic CTD PMID:20974942 NCBI chr18:31,614,143...31,621,489
Ensembl chr18:31,618,481...31,620,064
JBrowse link
G S100A8 S100 calcium binding protein A8 ISO RGD PMID:8343166 RGD:633930 NCBI chr 7:43,540,667...43,541,604
Ensembl chr 7:43,501,989...43,541,604
JBrowse link
G S100A9 S100 calcium binding protein A9 ISO RGD PMID:8343166 RGD:633930 NCBI chr 7:43,566,993...43,570,074 JBrowse link
G SAA1 serum amyloid A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15944321
G SERPINC1 serpin family C member 1 ISO protein:decreased expression:plasma RGD PMID:22781611 RGD:11035273 NCBI chr 7:25,322,668...25,333,022
Ensembl chr 7:25,316,129...25,332,987
JBrowse link
G SFRP4 secreted frizzled related protein 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25194984 NCBI chr18:12,018,049...12,028,123
Ensembl chr18:12,017,978...12,027,788
JBrowse link
G SHH sonic hedgehog signaling molecule treatment ISO RGD PMID:25821409 RGD:12879456 NCBI chr16:18,650,553...18,663,571
Ensembl chr16:18,484,809...18,662,903
JBrowse link
G SLC11A1 solute carrier family 11 member 1 severity ISO RGD PMID:17122779 RGD:5684943 NCBI chr37:25,039,203...25,047,461
Ensembl chr37:25,038,360...25,047,282
JBrowse link
G SLPI secretory leukocyte peptidase inhibitor treatment ISO protein:decreased expression:articular cartilage of joint RGD PMID:9744360 PMID:10449524 RGD:634208 RGD:9999431 NCBI chr24:32,566,030...32,568,406
Ensembl chr24:32,566,026...32,568,420
JBrowse link
G SMO smoothened, frizzled class receptor treatment ISO RGD PMID:25821409 RGD:12879456 NCBI chr14:7,518,871...7,527,703
Ensembl chr14:7,518,856...7,528,033
JBrowse link
G SOCS3 suppressor of cytokine signaling 3 ISO mRNA:increased expression:mononuclear cell RGD PMID:16507131 RGD:1625684 NCBI chr 9:2,859,267...2,859,944 JBrowse link
G SPN sialophorin ISO associated with Staphylococcal Infections RGD PMID:7927732 RGD:2303983 NCBI chr 6:17,770,303...17,774,946 JBrowse link
G STAT1 signal transducer and activator of transcription 1 ISO protein:increased tyrosine phosphorylation:macrophage, synovial cell
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:14674010 PMID:15188379 RGD:1582346 NCBI chr37:1,513,438...1,549,837
Ensembl chr37:1,507,219...1,550,178
JBrowse link
G STAT3 signal transducer and activator of transcription 3 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:15188379 PMID:21937456 PMID:23711144 RGD:10403081 NCBI chr 9:20,539,660...20,614,631
Ensembl chr 9:20,539,697...20,612,672
JBrowse link
G TAC1 tachykinin precursor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:9259450 NCBI chr14:22,631,106...22,640,283
Ensembl chr14:22,632,642...22,640,258
JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 ISO protein:increased expression:synovium RGD PMID:9010265 RGD:1601623 NCBI chr23:13,886,869...13,946,480
Ensembl chr23:13,889,000...13,977,636
JBrowse link
G THBD thrombomodulin ISO RGD PMID:16879225 RGD:5685015 NCBI chr24:599,773...601,649
Ensembl chr24:599,773...601,649
JBrowse link
G TIMP4 TIMP metallopeptidase inhibitor 4 ISO RGD PMID:12483743 RGD:2290463 NCBI chr20:6,399,522...6,405,089
Ensembl chr20:6,399,522...6,405,089
JBrowse link
G TJP1 tight junction protein 1 ISO RGD PMID:18848892 RGD:2325138 NCBI chr 3:38,997,122...39,076,617
Ensembl chr 3:38,997,076...39,241,574
JBrowse link
G TLR2 toll like receptor 2 ISO RGD PMID:20131263 PMID:21725847 RGD:7241099 RGD:8552884 NCBI chr15:51,454,557...51,465,429
Ensembl chr15:51,454,695...51,465,241
JBrowse link
G TLR3 toll like receptor 3 ISO RGD PMID:20500834 RGD:5128706 NCBI chr16:44,617,012...44,633,591
Ensembl chr16:44,550,846...44,653,247
JBrowse link
G TNF tumor necrosis factor treatment ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:serum:
RGD
CTD
PMID:7589090 PMID:9598899 PMID:19169271 PMID:19203382 PMID:19330884 More... RGD:10450611 RGD:10755447 RGD:13792834 RGD:7193038 RGD:7245941 RGD:8661761 RGD:8662976 NCBI chr12:1,074,561...1,076,425
Ensembl chr12:1,074,552...1,076,425
JBrowse link
G TNFRSF11B TNF receptor superfamily member 11b treatment ISO CTD Direct Evidence: therapeutic
Sinomenine CHEBI:9163
mRNA:decreased expression:bone
CTD
RGD
PMID:16696922 PMID:23333834 PMID:24066131 RGD:1624171 RGD:42721982 NCBI chr13:18,155,765...18,183,263
Ensembl chr13:18,156,367...18,183,444
JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A treatment ISO RGD PMID:20370892 PMID:21690068 PMID:23052485 RGD:7245941 RGD:8661729 RGD:8661761 NCBI chr27:38,641,837...38,654,693
Ensembl chr27:38,638,753...38,700,282
JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B treatment ISO human protein in rat model RGD PMID:21463515 PMID:21690068 PMID:23052485 RGD:5131255 RGD:7245941 RGD:8661761 NCBI chr 2:84,140,179...84,151,219
Ensembl chr 2:84,141,911...84,157,191
JBrowse link
G TRPV2 transient receptor potential cation channel subfamily V member 2 treatment ISO RGD PMID:25869297 RGD:9999444 NCBI chr 5:39,488,155...39,512,454
Ensembl chr 5:39,491,484...39,509,902
JBrowse link
G TXNDC5 thioredoxin domain containing 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23326410 NCBI chr35:7,834,135...7,854,836
Ensembl chr35:7,834,331...7,854,852
JBrowse link
G VEGFA vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism CTD PMID:9598899 PMID:26221077 NCBI chr12:12,209,032...12,224,978
Ensembl chr12:12,208,231...12,224,965
JBrowse link
G VIM vimentin ISO RGD PMID:7516431 RGD:6480480 NCBI chr 2:19,671,316...19,679,367
Ensembl chr 2:19,671,316...19,679,466
JBrowse link
G VIP vasoactive intestinal peptide ISO RGD PMID:19055696 PMID:21998117 RGD:5685376 RGD:5685612 NCBI chr 1:42,941,655...42,950,160
Ensembl chr 1:42,941,224...42,950,700
JBrowse link
G XDH xanthine dehydrogenase ISO protein:increased expression:brain, mitochondrion RGD PMID:25870945 RGD:13208957 NCBI chr17:24,900,708...24,960,748
Ensembl chr17:24,901,447...24,971,935
JBrowse link
G XYLT1 xylosyltransferase 1 ISO mRNA:decreased expression:articular cartilage RGD PMID:19001053 RGD:2313142 NCBI chr 6:26,742,853...27,041,666
Ensembl chr 6:26,742,853...27,041,666
JBrowse link
Experimental Autoimmune Encephalomyelitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM17 ADAM metallopeptidase domain 17 ISO RGD PMID:15878627 RGD:1559178 NCBI chr17:6,589,874...6,638,788
Ensembl chr17:6,589,878...6,638,731
JBrowse link
G ADAM8 ADAM metallopeptidase domain 8 ISO RGD PMID:9670863 RGD:2325244 NCBI chr28:40,853,665...40,865,604
Ensembl chr28:40,855,509...40,863,747
JBrowse link
G AIF1 allograft inflammatory factor 1 ISO protein:altered expression:spinal cord (rat) RGD PMID:19246105 RGD:2313022 NCBI chr12:1,104,350...1,106,179
Ensembl chr12:1,104,394...1,106,177
JBrowse link
G AKAP12 A-kinase anchoring protein 12 ISO mRNA,protein:increased expression:spinal cord RGD PMID:20155814 RGD:14348972 NCBI chr 1:41,614,893...41,712,350
Ensembl chr 1:41,614,714...41,709,798
JBrowse link
G ALOX15 arachidonate 15-lipoxygenase ISO RGD PMID:15328042 RGD:5509618 NCBI chr 5:31,883,544...31,891,357
Ensembl chr 5:31,882,501...32,038,119
JBrowse link
G AMIGO2 adhesion molecule with Ig like domain 2 severity ISO RGD PMID:28119027 RGD:14392778 NCBI chr27:7,507,426...7,510,015
Ensembl chr27:7,507,489...7,509,054
JBrowse link
G ANXA1 annexin A1 ISO protein:increased expression:brain, astrocyte, macrophage RGD PMID:9472682 RGD:2306942 NCBI chr 1:84,744,159...84,763,011
Ensembl chr 1:84,744,163...84,763,011
JBrowse link
G APOE apolipoprotein E ISO RGD PMID:28578430 RGD:13703134 NCBI chr 1:110,525,717...110,528,534
Ensembl chr 1:110,525,722...110,528,440
JBrowse link
G AQP4 aquaporin 4 disease_progression
severity
ISO RGD PMID:19660138 PMID:21056916 PMID:21157915 PMID:23707078 RGD:5148015 RGD:5490116 RGD:5490117 RGD:8696030 NCBI chr 7:61,855,617...61,868,953
Ensembl chr 7:61,855,744...61,865,089
JBrowse link
G B2M beta-2-microglobulin ISO RGD PMID:15837577 RGD:6482690 NCBI chr30:11,331,574...11,337,991
Ensembl chr30:11,331,569...11,337,997
JBrowse link
G B4GALT6 beta-1,4-galactosyltransferase 6 ISO mRNA:increased expression:astrocyte RGD PMID:25216636 RGD:14390079 NCBI chr 7:57,849,872...57,917,289
Ensembl chr 7:57,849,884...57,914,360
JBrowse link
G B9D2 B9 domain containing 2 ISO mRNA, protein:increased expression:central nervous system RGD PMID:17204936 RGD:2302088 NCBI chr 1:112,621,832...112,627,726
Ensembl chr 1:112,621,633...112,643,885
JBrowse link
G BDNF brain derived neurotrophic factor ISO RGD PMID:23212569 RGD:10059360 NCBI chr21:48,191,580...48,243,699
Ensembl chr21:48,192,670...48,204,480
JBrowse link
G C3 complement C3 ISO protein:increased expression:cerebrospinal fluid RGD PMID:22320401 RGD:7175513 NCBI chr20:53,566,226...53,598,365
Ensembl chr20:53,566,261...53,598,761
JBrowse link
G C6 complement C6 severity ISO RGD PMID:11970970 RGD:625607 NCBI chr 4:68,223,626...68,318,773
Ensembl chr 4:68,253,255...68,318,252
JBrowse link
G CACNA1B calcium voltage-gated channel subunit alpha1 B ISO RGD PMID:11353727 RGD:1580151 NCBI chr 9:47,813,625...48,009,532
Ensembl chr 9:47,816,393...48,009,406
JBrowse link
G CASP3 caspase 3 ISO protein:increased activity, increased expression:spinal cord RGD PMID:18521931 RGD:2311436 NCBI chr16:45,920,074...45,940,507
Ensembl chr16:45,920,071...45,940,505
JBrowse link
G CASP8 caspase 8 ISO protein:increased activity, increased expression:spinal cord RGD PMID:18521931 RGD:2311436 NCBI chr37:10,362,071...10,402,108
Ensembl chr37:10,391,048...10,401,822
JBrowse link
G CASP9 caspase 9 ISO protein:increased expression:spinal cord RGD PMID:18521931 RGD:2311436 NCBI chr 2:82,033,759...82,076,710
Ensembl chr 2:82,031,563...82,090,484
JBrowse link
G CAV3 caveolin 3 onset ISO Protein:increased expression:spinal cord, astrocyte RGD PMID:15925413 RGD:1582168 NCBI chr20:9,384,901...9,398,055
Ensembl chr20:9,384,901...9,401,196
JBrowse link
G CBLB Cbl proto-oncogene B ISO CTD Direct Evidence: marker/mechanism CTD PMID:20453840 NCBI chr33:11,255,453...11,665,755
Ensembl chr33:11,199,863...11,530,810
JBrowse link
G CCL1 C-C motif chemokine ligand 1 ISO mRNA:decreased expression:lymph node RGD PMID:19865101 RGD:4145472 NCBI chr 9:38,931,895...38,936,969
Ensembl chr 9:38,933,514...38,961,187
JBrowse link
G CCL2 C-C motif chemokine ligand 2 ISO mRNA:increased expression:spinal cord
mRNA:decreased expression:lymph node
mRNA:increased expression:optic chiasma (rat)
RGD PMID:11241588 PMID:17666800 PMID:19865101 RGD:2307114 RGD:4145472 RGD:8548888 NCBI chr 9:39,008,187...39,009,932 JBrowse link
G CCL5 C-C motif chemokine ligand 5 ISO protein:increased expression:brain (mouse)
mRNA:increased expression:spinal cord
RGD PMID:15833367 PMID:17666800 RGD:2307114 RGD:4890027 NCBI chr 9:37,817,409...37,823,852
Ensembl chr 9:37,817,305...37,823,852
JBrowse link
G CCR1 chemokine (C-C motif) receptor 1 ISO RGD PMID:14512166 PMID:14655765 RGD:5688165 RGD:5688167 NCBI chr20:42,421,356...42,427,177
Ensembl chr20:42,421,356...42,426,958
JBrowse link
G CCR2 C-C motif chemokine receptor 2 ISO mRNA:increased expression:spinal cord RGD PMID:9655467 RGD:632391 NCBI chr20:42,305,344...42,313,258
Ensembl chr20:42,307,580...42,308,698
JBrowse link
G CCR3 C-C motif chemokine receptor 3 ISO RGD PMID:15034073 RGD:6893394 NCBI chr20:42,382,380...42,398,449
Ensembl chr20:42,383,135...42,384,217
JBrowse link
G CCR5 C-C motif chemokine receptor 5 ISO mRNA:increased expression:spinal cord, macrophage, microglia (rat) RGD PMID:17484785 RGD:4890436 NCBI chr20:42,293,288...42,297,952
Ensembl chr20:42,294,996...42,297,952
JBrowse link
G CD28 CD28 molecule ISO RGD PMID:16061730 RGD:2307203 NCBI chr37:12,503,849...12,536,362
Ensembl chr37:12,503,811...12,532,854
JBrowse link
G CD4 CD4 molecule treatment ISO protein:decreased expression:T lymphocyte: RGD PMID:3097071 PMID:9138014 RGD:10058963 RGD:10058968 NCBI chr27:38,204,003...38,250,771
Ensembl chr27:38,204,003...38,250,771
JBrowse link
G CD80 CD80 molecule ISO RGD PMID:9379015 RGD:6902906 NCBI chr33:23,177,136...23,208,421
Ensembl chr33:23,177,138...23,201,380
JBrowse link
G CD86 CD86 molecule disease_progression
resistance
ISO protein:increased expression:spinal cord, blood vessel (rat) RGD PMID:10477557 PMID:20451260 RGD:4892207 RGD:4892227 NCBI chr33:25,256,267...25,318,855
Ensembl chr33:25,256,267...25,318,087
JBrowse link
G CIITA class II major histocompatibility complex transactivator ISO RGD PMID:15821736 RGD:1358146 NCBI chr 6:31,774,486...31,837,025
Ensembl chr 6:31,774,609...31,836,820
JBrowse link
G CNP 2',3'-cyclic nucleotide 3' phosphodiesterase ISO RGD PMID:7541143 PMID:10650887 PMID:21107918 RGD:6483335 RGD:6483351 RGD:6483353 NCBI chr 9:20,888,350...20,896,139
Ensembl chr 9:20,886,574...20,896,079
JBrowse link
G COMT catechol-O-methyltransferase treatment ISO RGD PMID:25242632 RGD:13450949 NCBI chr26:29,359,930...29,381,854
Ensembl chr26:29,360,356...29,366,008
JBrowse link
G CPB2 carboxypeptidase B2 ISO RGD PMID:22768796 RGD:7243111 NCBI chr22:5,074,805...5,126,635
Ensembl chr22:5,074,816...5,126,170
JBrowse link
G CRSP-3 calcitonin receptor-stimulating peptide 3 no_association ISO RGD PMID:19563774 RGD:5684360 NCBI chr21:37,676,841...37,680,643
Ensembl chr21:37,676,841...37,680,645
JBrowse link
G CSPG4 chondroitin sulfate proteoglycan 4 ISO protein:increased expression:spinal cord RGD PMID:20162860 PMID:21679768 RGD:5686852 RGD:5686863 NCBI chr30:38,465,486...38,498,365
Ensembl chr30:38,465,241...38,497,971
JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 ISO RGD PMID:9379015 RGD:6902906 NCBI chr37:12,647,712...12,653,874
Ensembl chr37:12,634,563...12,653,874
JBrowse link
G CTSC cathepsin C ISO RGD PMID:843913 RGD:1599653 NCBI chr21:11,659,296...11,692,957
Ensembl chr21:11,659,292...11,692,816
JBrowse link
G CTSS cathepsin S ISO RGD PMID:21439785 RGD:5686915 NCBI chr17:59,893,840...59,910,878
Ensembl chr17:59,893,840...59,910,849
JBrowse link
G CX3CL1 C-X3-C motif chemokine ligand 1 ISO RGD PMID:16053521 RGD:4891973 NCBI chr 2:59,022,794...59,032,095
Ensembl chr 2:59,022,794...59,032,095
JBrowse link
G CX3CR1 C-X3-C motif chemokine receptor 1 ISO RGD PMID:16053521 PMID:24706865 RGD:4891973 RGD:9491767 NCBI chr23:8,937,069...8,954,738
Ensembl chr23:8,938,906...8,952,808
JBrowse link
G CXCR2 C-X-C motif chemokine receptor 2 ISO RGD PMID:19616545 RGD:7257694 NCBI chr37:24,831,351...24,846,387
Ensembl chr37:24,843,171...24,844,247
JBrowse link
G CXCR3 C-X-C motif chemokine receptor 3 ISO RGD PMID:21038468 RGD:5135506 NCBI chr  X:55,882,433...55,884,582
Ensembl chr  X:55,882,433...55,884,582
JBrowse link
G DAB2 DAB adaptor protein 2 disease_progression ISO RGD PMID:21890121 RGD:7243155 NCBI chr 4:69,625,874...69,648,349
Ensembl chr 4:69,625,527...69,648,321
JBrowse link
G DLA-DRA MHC class II DR alpha chain ISO RGD PMID:8676084 RGD:5490166 NCBI chr12:2,133,026...2,137,825
Ensembl chr12:2,132,499...2,168,975
JBrowse link
G DLK1 delta like non-canonical Notch ligand 1 ISO RGD PMID:24676147 RGD:150520045 NCBI chr 8:68,961,975...68,970,106
Ensembl chr 8:68,961,744...68,972,761
JBrowse link
G DLL1 delta like canonical Notch ligand 1 ISO RGD PMID:17947672 RGD:6482235 NCBI chr12:72,265,078...72,272,347
Ensembl chr12:72,265,682...72,272,348
JBrowse link
G DUSP10 dual specificity phosphatase 10 ISO RGD PMID:15306813 RGD:7775013 NCBI chr38:16,196,354...16,233,640
Ensembl chr38:16,196,635...16,231,315
JBrowse link
G ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 disease_progression ISO RGD PMID:19524108 RGD:9685491 NCBI chr28:9,181,851...9,311,835
Ensembl chr28:9,211,050...9,323,939
JBrowse link
G EPO erythropoietin ISO CTD Direct Evidence: therapeutic CTD PMID:18382691 NCBI chr 6:8,994,211...8,995,954
Ensembl chr 6:8,994,211...8,996,144
JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30661753 NCBI chr 9:11,930,614...12,006,724
Ensembl chr 9:11,934,965...12,006,814
JBrowse link
G ESR2 estrogen receptor 2 ISO RGD PMID:21182085 PMID:21565615 RGD:5508732 RGD:5508735 NCBI chr 8:38,645,917...38,715,347
Ensembl chr 8:38,645,430...38,702,691
JBrowse link
G FASLG Fas ligand treatment ISO RGD PMID:10944459 RGD:12903984 NCBI chr 7:26,335,837...26,344,224
Ensembl chr 7:26,335,846...26,344,224
JBrowse link
G FGF2 fibroblast growth factor 2 ISO mRNA:increased expression:spinal cord RGD PMID:8929896 PMID:9814819 RGD:8655647 RGD:9831448 NCBI chr19:17,403,288...17,463,143
Ensembl chr19:16,994,661...17,463,151
JBrowse link
G FLT1 fms related receptor tyrosine kinase 1 treatment ISO RGD PMID:18721816 RGD:10402153 NCBI chr25:11,231,958...11,410,379
Ensembl chr25:11,231,737...11,407,621
JBrowse link
G FOXO3 forkhead box O3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27742544 NCBI chr12:65,552,455...65,673,467
Ensembl chr12:65,552,310...65,670,198
JBrowse link
G GHRH growth hormone releasing hormone resistance ISO RGD PMID:21846799 RGD:5687168 NCBI chr24:25,893,224...25,902,095
Ensembl chr24:25,893,225...25,897,712
JBrowse link
G GHRL ghrelin and obestatin prepropeptide treatment ISO RGD PMID:19620309 RGD:12905041 NCBI chr20:8,092,921...8,097,512
Ensembl chr20:8,092,957...8,097,510
JBrowse link
G GJC2 gap junction protein gamma 2 ISO protein:decreased expression:white matter of spinal cord, gap junction (mouse) RGD PMID:22461072 RGD:13208593 NCBI chr14:810,388...819,248
Ensembl chr14:810,386...820,420
JBrowse link
G GLI1 GLI family zinc finger 1 ISO RGD PMID:18991353 RGD:12801440 NCBI chr10:1,565,306...1,575,971
Ensembl chr10:1,565,244...1,575,982
JBrowse link
G GLUD1 glutamate dehydrogenase 1 ISO mRNA, protein:decreased expression:spinal cord RGD PMID:9145307 RGD:6484657 NCBI chr 4:34,629,046...34,662,711 JBrowse link
G HAVCR2 hepatitis A virus cellular receptor 2 ISO mRNA:increased expression:spinal cord: RGD PMID:11823861 PMID:15913792 RGD:9686086 RGD:9686113 NCBI chr 4:53,018,990...53,032,035
Ensembl chr 4:53,012,234...53,033,393
JBrowse link
G HLA-DRB1 MHC class II DLA DRB1 beta chain ISO RGD PMID:16194572 RGD:5147647 NCBI chr12:2,151,409...2,164,564 JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase ISO RGD PMID:14691063 PMID:17085013 RGD:5508469 RGD:5508476 NCBI chr 3:30,970,037...30,988,987
Ensembl chr 3:30,970,037...30,990,294
JBrowse link
G IFNG interferon gamma treatment
disease_progression
ISO RGD PMID:15661899 PMID:22896638 RGD:10755692 RGD:7987912 NCBI chr10:10,406,866...10,411,698
Ensembl chr10:10,406,867...10,411,698
JBrowse link
G IGF1 insulin like growth factor 1 treatment ISO human protein in a rat model RGD PMID:7541143 RGD:6483353 NCBI chr15:41,203,320...41,275,964
Ensembl chr15:41,202,518...41,275,794
JBrowse link
G IL10 interleukin 10 treatment ISO RGD PMID:23872438 RGD:7364993 NCBI chr 7:5,933,285...5,937,057
Ensembl chr 7:5,933,285...5,937,057
JBrowse link
G IL10RA interleukin 10 receptor subunit alpha ISO RGD PMID:12620647 RGD:2316323 NCBI chr 5:15,675,775...15,688,935
Ensembl chr 5:15,677,547...15,682,163
JBrowse link
G IL12A interleukin 12A ISO RGD PMID:12471147 RGD:724447 NCBI chr34:26,125,529...26,133,546
Ensembl chr34:26,124,770...26,133,550
JBrowse link
G IL12B interleukin 12B ISO mRNA, protein:increased expression:lymph node RGD PMID:19233473 RGD:4831840 NCBI chr 4:51,178,637...51,194,606
Ensembl chr 4:51,183,568...51,193,228
JBrowse link
G IL13 interleukin 13 severity ISO RGD PMID:7523520 PMID:18250480 RGD:5684366 RGD:5684367 NCBI chr11:20,957,870...20,961,391
Ensembl chr11:20,958,464...20,961,388
JBrowse link
G IL16 interleukin 16 ISO RGD PMID:17641011 RGD:5024940 NCBI chr 3:56,473,485...56,575,504
Ensembl chr 3:56,473,486...56,575,104
JBrowse link
G IL17A interleukin 17A treatment ISO mRNA, protein:increased expression:lymph node RGD PMID:16200068 PMID:16785554 PMID:19233473 PMID:20003332 RGD:4831840 RGD:4888522 RGD:4889113 RGD:9212317 NCBI chr12:19,854,129...19,862,521
Ensembl chr12:19,854,129...19,862,513
JBrowse link
G IL18 interleukin 18 ISO mRNA:increased expression:spinal cord RGD PMID:9834127 PMID:9846824 RGD:4889542 RGD:4889543 NCBI chr 5:20,972,742...20,995,327
Ensembl chr 5:20,972,871...20,995,348
JBrowse link
G IL18R1 interleukin 18 receptor 1 ISO mRNA:increased expression:lymph node RGD PMID:19269041 RGD:2311529 NCBI chr10:40,614,336...40,653,300
Ensembl chr10:40,615,312...40,653,454
JBrowse link
G IL1RN interleukin 1 receptor antagonist treatment ISO human protein in a rat model RGD PMID:7593560 RGD:8551836 NCBI chr17:37,236,690...37,250,424
Ensembl chr17:37,212,751...37,249,329
JBrowse link
G IL21 interleukin 21 ISO RGD PMID:18997868 RGD:5147399 NCBI chr19:17,641,833...17,651,275
Ensembl chr19:17,641,833...17,651,266
JBrowse link
G IL21R interleukin 21 receptor disease_progression
no_association
ISO RGD PMID:18353312 PMID:18546146 RGD:6892939 RGD:6892940 NCBI chr 6:19,181,846...19,217,915
Ensembl chr 6:19,182,071...19,217,931
JBrowse link
G IL22 interleukin 22 ISO RGD PMID:19269041 RGD:2311529 NCBI chr10:10,487,367...10,492,238
Ensembl chr10:10,487,262...10,492,371
JBrowse link
G IL27 interleukin 27 ISO protein:decreased expression:blood serum (mouse) RGD PMID:33403844 RGD:126790527 NCBI chr 6:18,243,988...18,248,369
Ensembl chr 6:18,244,040...18,247,635
JBrowse link
G IL2RA interleukin 2 receptor subunit alpha ISO RGD PMID:19269041 RGD:2311529 NCBI chr 2:29,892,130...29,948,926
Ensembl chr 2:29,894,125...29,944,643
JBrowse link
G IL32 interleukin 32 ameliorates ISO human gene in a mouse model RGD PMID:26564962 RGD:150340739 NCBI chr 6:38,119,287...38,122,979 JBrowse link
G IL4 interleukin 4 treatment ISO RGD PMID:1383385 PMID:18239607 RGD:7829778 RGD:8142395 NCBI chr11:20,972,693...20,981,539
Ensembl chr11:20,972,690...20,981,534
JBrowse link
G IL6 interleukin 6 ISO protein:increased expression:oligodendrocytes (rat) RGD PMID:9358769 PMID:23322593 RGD:12791289 RGD:2307412 NCBI chr14:36,474,268...36,478,519
Ensembl chr14:36,473,394...36,478,519
JBrowse link
G ITGA4 integrin subunit alpha 4 susceptibility
treatment
ISO rat bone marrow cells in a mouse model RGD PMID:12626659 PMID:18722022 RGD:9698418 RGD:9698436 NCBI chr36:24,670,464...24,686,719
Ensembl chr36:24,653,408...24,729,057
JBrowse link
G JAG1 jagged canonical Notch ligand 1 ISO RGD PMID:17947672 RGD:6482235 NCBI chr24:11,656,926...11,693,146
Ensembl chr24:11,657,416...11,692,199
JBrowse link
G JAK2 Janus kinase 2 ISO RGD PMID:22066025 RGD:6483041 NCBI chr 1:93,321,055...93,438,898
Ensembl chr 1:93,142,635...93,435,997
JBrowse link
G JAK3 Janus kinase 3 treatment ISO RGD PMID:25012120 RGD:11533939 NCBI chr20:45,051,135...45,068,445
Ensembl chr20:45,050,526...45,072,805
JBrowse link
G KDR kinase insert domain receptor ISO RGD PMID:19233483 RGD:5684404 NCBI chr13:47,442,861...47,484,574
Ensembl chr13:47,442,764...47,485,042
JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase ISO RGD PMID:25972476 RGD:12910744 NCBI chr13:47,108,442...47,190,935
Ensembl chr13:47,108,504...47,190,029
JBrowse link
G LOC100686073 metallothionein-1 ISO mRNA:increased expression:brain (mouse) RGD PMID:19619133 RGD:6484112 NCBI chr 2:59,603,021...59,604,173
Ensembl chr 2:59,603,014...59,604,132
JBrowse link
G LOC477699 alpha-2-macroglobulin treatment ISO RGD PMID:1710603 RGD:10046021 NCBI chr27:36,654,328...36,695,775 JBrowse link
G LOC491316 midkine ISO RGD PMID:9814819 RGD:9831448 NCBI chr 9:55,100,491...55,101,081 JBrowse link
G LOC607986 myelin associated oligodendrocyte basic protein ISO RGD PMID:10623862 RGD:27226694 NCBI chr23:9,121,277...9,176,128
Ensembl chr23:9,121,319...9,161,972
JBrowse link
G LRP1 LDL receptor related protein 1 ISO protein:increased expression:cerebellum, spinal cord RGD PMID:19299462 RGD:13800552 NCBI chr10:1,260,256...1,341,705
Ensembl chr10:1,260,719...1,352,271
JBrowse link
G LTA lymphotoxin alpha ISO mRNA:increased expression:brain
mRNA:increased expression:spinal cord
RGD PMID:7593556 PMID:9184655 RGD:1625038 RGD:4143220 NCBI chr12:1,070,608...1,073,053
Ensembl chr12:1,071,192...1,073,067
JBrowse link
G MAPT microtubule associated protein tau treatment ISO RGD PMID:15494405 RGD:1358431 NCBI chr 9:9,572,174...9,674,082
Ensembl chr 9:9,570,557...9,674,349
JBrowse link
G MBP myelin basic protein ISO CTD Direct Evidence: marker/mechanism
human sequence peptide in a rat model; associated with Herpesviridae infections
CTD
RGD
PMID:11501064 PMID:12811845 PMID:15159442 PMID:16285900 PMID:17884951 More... RGD:30296670 RGD:7349334 NCBI chr 1:2,841,801...2,952,553
Ensembl chr 1:2,846,589...2,951,860
JBrowse link
G MMP2 matrix metallopeptidase 2 ISO RGD PMID:19922364 RGD:2325703 NCBI chr 2:60,471,092...60,492,991
Ensembl chr 2:60,471,257...60,494,113
JBrowse link
G MMP7 matrix metallopeptidase 7 ISO RGD PMID:9549496 RGD:8547909 NCBI chr 5:29,187,902...29,196,157
Ensembl chr 5:29,187,851...29,196,153
JBrowse link
G MMP9 matrix metallopeptidase 9 treatment ISO protein:increased expression:multiple tissues RGD PMID:9549496 PMID:20810258 PMID:22800566 PMID:24797785 RGD:13204762 RGD:13204801 RGD:8547909 RGD:8547936 NCBI chr24:33,274,260...33,281,116
Ensembl chr24:33,274,268...33,281,293
JBrowse link
G MOG myelin oligodendrocyte glycoprotein ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:10384097 PMID:12799014 PMID:12904460 PMID:14624757 PMID:16931536 More... RGD:9685372 RGD:9685373 RGD:9685375 NCBI chr35:26,256,311...26,267,357
Ensembl chr35:26,256,489...26,266,832
JBrowse link
G MT-III transcription initiation factor TFIID subunit 4 ISO mRNA:increased expression:brain (mouse) RGD PMID:19619133 RGD:6484112 NCBI chr 2:59,624,845...59,630,386 JBrowse link
G MT2A metallothionein 1H ISO mRNA:increased expression:brain (mouse) RGD PMID:19619133 RGD:6484112 NCBI chr 2:59,607,926...59,608,825
Ensembl chr 2:59,607,927...59,626,727
JBrowse link
G NCAM1 neural cell adhesion molecule 1 ISO protein:decreased expression:hippocampus RGD PMID:17064783 RGD:40924670 NCBI chr 5:19,895,587...20,192,334
Ensembl chr 5:19,895,613...20,191,995
JBrowse link
G NEFL neurofilament light chain ISO protein:increased expression:cerebrospinal fluid, spinal cord RGD PMID:16182933 RGD:2299007 NCBI chr25:32,463,361...32,468,965
Ensembl chr25:32,463,452...32,467,224
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19910389 NCBI chr36:20,989,205...21,087,044
Ensembl chr36:20,989,360...21,012,524
JBrowse link
G NGF nerve growth factor ISO protein, mRNA:increased expression:thalamus and cortex, CNS RGD PMID:8866783 RGD:5508386 NCBI chr17:52,900,647...52,901,607
Ensembl chr17:52,900,647...52,901,607
JBrowse link
G NGFR nerve growth factor receptor severity ISO mRNA:increased expression:central nervous system RGD PMID:8866783 PMID:16519950 RGD:5508312 RGD:5508386 NCBI chr 9:25,598,468...25,621,021
Ensembl chr 9:25,601,074...25,623,274
JBrowse link
G NOS2 nitric oxide synthase 2 ISO RGD PMID:21857957 RGD:5509069 NCBI chr 9:42,171,821...42,210,217
Ensembl chr 9:42,171,821...42,208,588
JBrowse link
G NR1H2 nuclear receptor subfamily 1 group H member 2 ISO RGD PMID:21266776 RGD:6480877 NCBI chr 1:106,332,691...106,339,168
Ensembl chr 1:106,332,798...106,339,135
JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 ISO RGD PMID:17322387 RGD:4892331 NCBI chr 2:38,124,568...38,242,510
Ensembl chr 2:38,123,190...38,240,755
JBrowse link
G NTRK1 neurotrophic receptor tyrosine kinase 1 ISO mRNA:increased expression:brain subventricular zone: RGD PMID:15589512 RGD:5684777 NCBI chr 7:41,140,931...41,159,326
Ensembl chr 7:41,140,879...41,159,288
JBrowse link
G OLIG1 oligodendrocyte transcription factor 1 treatment ISO RGD PMID:24941845 RGD:40902822 NCBI chr31:27,718,925...27,721,301
Ensembl chr31:27,719,026...27,719,862
JBrowse link
G OLIG2 oligodendrocyte transcription factor 2 treatment ISO RGD PMID:24941845 PMID:29682587 RGD:40902822 RGD:40902863 NCBI chr31:27,674,112...27,677,521
Ensembl chr31:27,674,107...27,676,822
JBrowse link
G PDCD1 programmed cell death 1 susceptibility ISO RGD PMID:24648472 RGD:40818258 NCBI chr25:51,606,559...51,618,903
Ensembl chr25:51,608,173...51,618,723
JBrowse link
G PDGFB platelet derived growth factor subunit B treatment ISO RGD PMID:16042218 RGD:11080975 NCBI chr10:25,798,877...25,819,422
Ensembl chr10:25,798,938...25,817,746
JBrowse link
G PDGFRA platelet derived growth factor receptor alpha treatment ISO RGD PMID:16042218 RGD:11080975 NCBI chr13:46,729,722...46,775,828
Ensembl chr13:46,730,703...46,773,278
JBrowse link
G PDGFRB platelet derived growth factor receptor beta treatment ISO RGD PMID:16042218 RGD:11080975 NCBI chr 4:58,925,922...58,963,639
Ensembl chr 4:58,926,351...58,962,283
JBrowse link
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma ISO RGD PMID:20303183 RGD:6482686 NCBI chr18:13,576,966...13,611,748
Ensembl chr18:13,570,999...13,611,141
JBrowse link
G PLP1 proteolipid protein 1 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:21068375 PMID:24941845 RGD:40902822 NCBI chr  X:77,191,112...77,207,772
Ensembl chr  X:77,191,150...77,205,964
JBrowse link
G PPARA peroxisome proliferator activated receptor alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:17261635 NCBI chr10:19,934,020...20,006,096
Ensembl chr10:19,934,165...20,006,146
JBrowse link
G PRF1 perforin 1 ISO RGD PMID:20708278 RGD:6482806 NCBI chr 4:21,497,865...21,502,429
Ensembl chr 4:21,498,249...21,500,864
JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 severity ISO RGD PMID:19486896 RGD:6484540 NCBI chr 4:68,579,061...68,614,548
Ensembl chr 4:68,579,037...68,611,841
JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO protein:increased expression:cerebral cortex, cerebellum, spinal cord
protein:increased expression:microglia, macrophage,
RGD PMID:10229132 PMID:21667309 RGD:5688149 RGD:5688250 NCBI chr 9:60,195,118...60,216,847
Ensembl chr 9:60,195,124...60,216,819
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO protein:increased expression:cerebral cortex, cerebellum, spinal cord
protein:increased expression:endothelial cell
RGD PMID:10229132 PMID:21667309 RGD:5688149 RGD:5688250 NCBI chr 7:19,668,079...19,674,903
Ensembl chr 7:19,668,082...19,674,903
JBrowse link
G PTN pleiotrophin ISO mRNA:increased expression:spinal cord (rat) RGD PMID:9814819 RGD:9831448 NCBI chr16:11,283,078...11,382,820
Ensembl chr16:11,283,077...11,382,814
JBrowse link
G QKI QKI, KH domain containing RNA binding ISO RGD PMID:22740327 RGD:10045997 NCBI chr 1:51,800,294...51,956,891
Ensembl chr 1:51,800,309...51,952,714
JBrowse link
G RANGRF RAN guanine nucleotide release factor ISO RGD PMID:8557821 RGD:6771380 NCBI chr 5:33,084,355...33,085,810
Ensembl chr 5:33,084,397...33,085,812
JBrowse link
G RHOA ras homolog family member A severity ISO protein:increased expression:microglial cell, brain RGD PMID:17983427 RGD:2298887 NCBI chr20:39,824,552...39,888,089
Ensembl chr20:39,824,575...39,887,215
JBrowse link
G SERPINE1 serpin family E member 1 ISO mRNA,protein:increased expression,increased activity:spinal cord, astrocyte: RGD PMID:11733372 RGD:13208549 NCBI chr 6:8,719,547...8,727,160
Ensembl chr 6:8,720,825...8,726,301
JBrowse link
G SHH sonic hedgehog signaling molecule ISO RGD PMID:15892298 PMID:18991353 RGD:12801423 RGD:12801440 NCBI chr16:18,650,553...18,663,571
Ensembl chr16:18,484,809...18,662,903
JBrowse link
G SIGMAR1 sigma non-opioid intracellular receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30661753 NCBI chr11:51,310,672...51,313,426
Ensembl chr11:51,311,085...51,313,400
JBrowse link
G SIRT1 sirtuin 1 ISO CTD Direct Evidence: therapeutic CTD PMID:23547115 NCBI chr 4:19,188,616...19,220,031
Ensembl chr 4:19,188,675...19,218,279
JBrowse link
G SLPI secretory leukocyte peptidase inhibitor treatment ISO RGD PMID:22436018 RGD:9999395 NCBI chr24:32,566,030...32,568,406
Ensembl chr24:32,566,026...32,568,420
JBrowse link
G SNCB synuclein beta ISO RGD PMID:12496452 RGD:730073 NCBI chr 4:36,710,236...36,719,455
Ensembl chr 4:36,616,039...36,764,501
JBrowse link
G SRSF9 serine and arginine rich splicing factor 9 treatment ISO RGD PMID:20616573 RGD:11040805 NCBI chr26:16,363,275...16,369,699
Ensembl chr26:16,363,475...16,369,666
JBrowse link
G STAT1 signal transducer and activator of transcription 1 ISO RGD PMID:22066025 RGD:6483041 NCBI chr37:1,513,438...1,549,837
Ensembl chr37:1,507,219...1,550,178
JBrowse link
G STAT3 signal transducer and activator of transcription 3 ISO RGD PMID:17878325 PMID:22066025 RGD:6483041 RGD:6892946 NCBI chr 9:20,539,660...20,614,631
Ensembl chr 9:20,539,697...20,612,672
JBrowse link
G TGFB2 transforming growth factor beta 2 ISO mRNA, protein:decreased expression:central nervous system RGD PMID:17204936 RGD:2302088 NCBI chr38:13,430,832...13,511,655
Ensembl chr38:13,429,148...13,510,242
JBrowse link
G TIMP3 TIMP metallopeptidase inhibitor 3 ISO protein:increased expression:spinal cord RGD PMID:15878627 RGD:1559178 NCBI chr10:30,627,154...30,681,520
Ensembl chr10:30,627,154...30,694,288
JBrowse link
G TLR2 toll like receptor 2 ISO protein:increased expression:spinal cord RGD PMID:18644848 RGD:2312575 NCBI chr15:51,454,557...51,465,429
Ensembl chr15:51,454,695...51,465,241
JBrowse link
G TLR4 toll like receptor 4 ISO protein:increased expression:spinal cord RGD PMID:18644848 RGD:2312575 NCBI chr11:71,356,390...71,367,166
Ensembl chr11:71,356,390...71,367,165
JBrowse link
G TNF tumor necrosis factor treatment ISO RGD PMID:11421579 RGD:12904661 NCBI chr12:1,074,561...1,076,425
Ensembl chr12:1,074,552...1,076,425
JBrowse link
G VCAM1 vascular cell adhesion molecule 1 ISO RGD PMID:12196270 RGD:1580348 NCBI chr 6:49,341,669...49,359,841
Ensembl chr 6:49,342,151...49,359,933
JBrowse link
G VDR vitamin D receptor treatment ISO RGD PMID:21287548 PMID:21318047 RGD:13210791 RGD:8158064 NCBI chr27:6,852,915...6,909,466
Ensembl chr27:6,852,723...6,909,470
JBrowse link
G VEGFA vascular endothelial growth factor A ISO mRNA:decreased expression:Cerebrospinal Fluid:
mRNA,protein:decreased expression:spinal cord:
RGD PMID:12387457 PMID:17083617 RGD:634258 RGD:7421596 NCBI chr12:12,209,032...12,224,978
Ensembl chr12:12,208,231...12,224,965
JBrowse link
G VIP vasoactive intestinal peptide ISO RGD PMID:20978211 RGD:5685386 NCBI chr 1:42,941,655...42,950,160
Ensembl chr 1:42,941,224...42,950,700
JBrowse link
G XBP1 X-box binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30661753 NCBI chr26:22,162,675...22,168,149
Ensembl chr26:22,163,222...22,168,105
JBrowse link
Experimental Autoimmune Myasthenia Gravis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARPC5 actin related protein 2/3 complex subunit 5 treatment ISO RGD PMID:17997938 RGD:11049469 NCBI chr 7:16,976,392...16,986,015
Ensembl chr 7:16,977,555...16,985,943
JBrowse link
G C3 complement C3 ISO RGD PMID:147324 PMID:17962462 RGD:11040804 RGD:7401263 NCBI chr20:53,566,226...53,598,365
Ensembl chr20:53,566,261...53,598,761
JBrowse link
G C6 complement C6 susceptibility ISO RGD PMID:17034580 RGD:1600670 NCBI chr 4:68,223,626...68,318,773
Ensembl chr 4:68,253,255...68,318,252
JBrowse link
G CD40LG CD40 ligand treatment ISO RGD PMID:11359850 RGD:8547800 NCBI chr  X:107,001,421...107,023,007
Ensembl chr  X:107,010,890...107,023,006
JBrowse link
G CFB complement factor B treatment ISO RGD PMID:25355917 RGD:11041161 NCBI chr12:1,400,143...1,406,267 JBrowse link
G CHRNA1 cholinergic receptor nicotinic alpha 1 subunit treatment ISO RGD PMID:10606626 RGD:704386 NCBI chr36:18,726,243...18,742,505
Ensembl chr36:18,726,243...18,742,505
JBrowse link
G CTSL3 cathepsin L family member 3 ISO mRNA:increased expression:quadriceps (rat) RGD PMID:16365386 RGD:2315588 NCBI chr 1:72,215,774...72,219,093 JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 ISO RGD PMID:15843529 PMID:19232748 RGD:1598501 RGD:2311364 NCBI chr32:598,406...599,925
Ensembl chr32:597,987...599,979
JBrowse link
G CXCR3 C-X-C motif chemokine receptor 3 ISO RGD PMID:15843529 PMID:19232748 RGD:1598501 RGD:2311364 NCBI chr  X:55,882,433...55,884,582
Ensembl chr  X:55,882,433...55,884,582
JBrowse link
G IL15 interleukin 15 ISO protein:increased expression:skeletal muscle RGD PMID:11585642 RGD:1626617 NCBI chr19:1,339,607...1,364,762
Ensembl chr19:1,339,967...1,364,762
JBrowse link
G IL23R interleukin 23 receptor ISO mRNA:increased expression:lymph node RGD PMID:21193288 RGD:5108250 NCBI chr 5:43,307,422...43,369,806
Ensembl chr 5:43,308,982...43,368,474
JBrowse link
G IL2RA interleukin 2 receptor subunit alpha ISO RGD PMID:18250419 RGD:2325986 NCBI chr 2:29,892,130...29,948,926
Ensembl chr 2:29,894,125...29,944,643
JBrowse link
G IL4R interleukin 4 receptor ISO protein:increased expression:skeletal muscle RGD PMID:19395316 RGD:4889981 NCBI chr 6:19,254,183...19,280,973
Ensembl chr 6:19,254,487...19,389,291
JBrowse link
G MUSK muscle associated receptor tyrosine kinase ISO RGD PMID:17081697 RGD:2317084 NCBI chr11:65,552,320...65,642,165
Ensembl chr11:65,551,889...65,642,349
JBrowse link
G MYOG myogenin ISO RGD PMID:1312030 RGD:9686077 NCBI chr 7:112,116...114,604
Ensembl chr 7:112,034...113,892
JBrowse link
G RAPSN receptor associated protein of the synapse ISO protein:decreased expression:neuromuscular junction RGD PMID:19344765 RGD:8549750 NCBI chr18:42,199,160...42,210,668
Ensembl chr18:42,199,412...42,210,673
JBrowse link
Experimental Autoimmune Myocarditis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADIPOQ adiponectin, C1Q and collagen domain containing ISO RGD PMID:23674516 RGD:8695925 NCBI chr34:19,398,310...19,410,519
Ensembl chr34:19,354,825...19,409,844
JBrowse link
G AGER advanced glycosylation end-product specific receptor ISO protein:increased expression:heart RGD PMID:24599045 RGD:8696002 NCBI chr12:1,574,251...1,577,410
Ensembl chr12:1,574,251...1,577,129
JBrowse link
G CASP3 caspase 3 treatment ISO RGD PMID:23833961 PMID:28903333 RGD:13702869 RGD:13702874 NCBI chr16:45,920,074...45,940,507
Ensembl chr16:45,920,071...45,940,505
JBrowse link
G CASP8 caspase 8 treatment ISO RGD PMID:23833961 RGD:13702874 NCBI chr37:10,362,071...10,402,108
Ensembl chr37:10,391,048...10,401,822
JBrowse link
G CASP9 caspase 9 treatment ISO RGD PMID:23833961 RGD:13702874 NCBI chr 2:82,033,759...82,076,710
Ensembl chr 2:82,031,563...82,090,484
JBrowse link
G CAV1 caveolin 1 ISO RGD PMID:17060028 RGD:1625364 NCBI chr14:55,458,934...55,494,563
Ensembl chr14:55,461,048...55,492,935
JBrowse link
G CAV2 caveolin 2 ISO RGD PMID:17060028 RGD:1625364 NCBI chr14:55,437,622...55,445,481
Ensembl chr14:55,437,622...55,445,469
JBrowse link
G CCL2 C-C motif chemokine ligand 2 disease_progression ISO mRNA, protein:increased expression:heart, serum (rat) RGD PMID:11472393 RGD:8549580 NCBI chr 9:39,008,187...39,009,932 JBrowse link
G CD28 CD28 molecule severity
treatment
ISO RGD PMID:8759765 PMID:19907173 RGD:13702882 RGD:13702883 NCBI chr37:12,503,849...12,536,362
Ensembl chr37:12,503,811...12,532,854
JBrowse link
G CD40 CD40 molecule treatment ISO RGD PMID:25297507 RGD:13702884 NCBI chr24:33,352,992...33,383,488
Ensembl chr24:33,372,930...33,383,301
JBrowse link
G FGL2 fibrinogen like 2 severity ISO RGD PMID:28892130 RGD:38549573 NCBI chr18:17,328,794...17,335,429
Ensembl chr18:17,331,780...17,335,401
JBrowse link
G FOXP3 forkhead box P3 severity
treatment
ISO RGD PMID:19907173 PMID:28892130 RGD:13702882 RGD:38549573 NCBI chr  X:42,331,229...42,362,841
Ensembl chr  X:42,344,108...42,350,758
JBrowse link
G GRK2 G protein-coupled receptor kinase 2 treatment ISO RGD PMID:30024944 RGD:13792695 NCBI chr18:50,148,566...50,167,422
Ensembl chr18:50,148,598...50,167,428
JBrowse link
G HAMP hepcidin antimicrobial peptide ISO mRNA:increased expression:heart RGD PMID:19615879 RGD:11041636 NCBI chr 1:117,305,531...117,306,587
Ensembl chr 1:117,305,411...117,306,619
JBrowse link
G HMGB1 high mobility group box 1 ISO protein:increased expression:heart, serum RGD PMID:24599045 RGD:8696002 NCBI chr25:9,431,223...9,558,167
Ensembl chr25:9,431,218...9,558,165
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 treatment ISO RGD PMID:21927577 RGD:5685668 NCBI chr 9:57,850,870...57,855,607
Ensembl chr 9:57,850,922...57,855,257
JBrowse link
G ICAM1 intercellular adhesion molecule 1 treatment ISO RGD PMID:11701617 RGD:13702911 NCBI chr20:50,818,715...50,827,914
Ensembl chr20:50,818,715...50,827,914
JBrowse link
G IL10 interleukin 10 treatment ISO RGD PMID:19907173 RGD:13702882 NCBI chr 7:5,933,285...5,937,057
Ensembl chr 7:5,933,285...5,937,057
JBrowse link
G IL13 interleukin 13 treatment ISO RGD PMID:15902684 RGD:8549607 NCBI chr11:20,957,870...20,961,391
Ensembl chr11:20,958,464...20,961,388
JBrowse link
G IL1RN interleukin 1 receptor antagonist treatment ISO mouse gene in a rat model RGD PMID:15795329 RGD:8551728 NCBI chr17:37,236,690...37,250,424
Ensembl chr17:37,212,751...37,249,329
JBrowse link
G IL6 interleukin 6 treatment ISO RGD PMID:26339812 RGD:11062109 NCBI chr14:36,474,268...36,478,519
Ensembl chr14:36,473,394...36,478,519
JBrowse link
G KCNA5 potassium voltage-gated channel subfamily A member 5 ISO RGD PMID:15306225 RGD:7242784 NCBI chr27:39,808,987...39,810,789
Ensembl chr27:39,756,363...39,811,035
JBrowse link
G MYH6 myosin heavy chain 6 ISO RGD PMID:10199887 RGD:12792956
G PPARG peroxisome proliferator activated receptor gamma ISO protein:increased expression:myocardium (rat) RGD PMID:15167281 RGD:8553039 NCBI chr20:6,134,618...6,265,481
Ensembl chr20:6,050,357...6,207,981
JBrowse link
G RORC RAR related orphan receptor C severity ISO RGD PMID:28892130 RGD:38549573 NCBI chr17:60,821,498...60,842,485
Ensembl chr17:60,821,981...60,842,453
JBrowse link
G RPS6 ribosomal protein S6 ISO RGD PMID:22014063 RGD:11041642 NCBI chr11:39,161,422...39,165,148
Ensembl chr11:39,161,422...39,165,148
JBrowse link
G SIRT1 sirtuin 1 treatment ISO RGD PMID:17322642 RGD:9586020 NCBI chr 4:19,188,616...19,220,031
Ensembl chr 4:19,188,675...19,218,279
JBrowse link
Experimental Autoimmune Neuritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM8 ADAM metallopeptidase domain 8 ISO RGD PMID:9670863 RGD:2325244 NCBI chr28:40,853,665...40,865,604
Ensembl chr28:40,855,509...40,863,747
JBrowse link
G AIF1 allograft inflammatory factor 1 ISO protein:increased expression:spinal cord (rat) RGD PMID:15710454 RGD:2313042 NCBI chr12:1,104,350...1,106,179
Ensembl chr12:1,104,394...1,106,177
JBrowse link
G ANXA1 annexin A1 ISO protein:increased expression:sciatic nerve RGD PMID:10603033 RGD:2306914 NCBI chr 1:84,744,159...84,763,011
Ensembl chr 1:84,744,163...84,763,011
JBrowse link
G APP amyloid beta precursor protein treatment ISO RGD PMID:28446186 RGD:13782060 NCBI chr31:21,351,207...21,614,466
Ensembl chr31:21,351,207...21,614,337
JBrowse link
G CAV1 caveolin 1 ISO protein:increased phosphorylation:sciatic nerve RGD PMID:17234162 RGD:2289125 NCBI chr14:55,458,934...55,494,563
Ensembl chr14:55,461,048...55,492,935
JBrowse link
G CCR1 chemokine (C-C motif) receptor 1 ISO protein:increased expression:sciatic nerve, macrophage, T cell RGD PMID:20500551 RGD:5688140 NCBI chr20:42,421,356...42,427,177
Ensembl chr20:42,421,356...42,426,958
JBrowse link
G CD14 CD14 molecule severity ISO RGD PMID:19162137 RGD:2312712 NCBI chr 2:35,790,505...35,792,967 JBrowse link
G CD28 CD28 molecule ISO RGD PMID:12864982 RGD:2307204 NCBI chr37:12,503,849...12,536,362
Ensembl chr37:12,503,811...12,532,854
JBrowse link
G CD40 CD40 molecule ISO RGD PMID:17188497 RGD:5491181 NCBI chr24:33,352,992...33,383,488
Ensembl chr24:33,372,930...33,383,301
JBrowse link
G CD40LG CD40 ligand ISO RGD PMID:17188497 RGD:5491181 NCBI chr  X:107,001,421...107,023,007
Ensembl chr  X:107,010,890...107,023,006
JBrowse link
G CD59 CD59 molecule ISO protein:increased expression:Schwann cell (rat) RGD PMID:10450801 RGD:1600494 NCBI chr18:33,977,433...33,999,145
Ensembl chr18:33,977,480...33,998,329
JBrowse link
G CX3CL1 C-X3-C motif chemokine ligand 1 ISO RGD PMID:18448252 RGD:4891968 NCBI chr 2:59,022,794...59,032,095
Ensembl chr 2:59,022,794...59,032,095
JBrowse link
G CX3CR1 C-X3-C motif chemokine receptor 1 ISO RGD PMID:18448252 RGD:4891968 NCBI chr23:8,937,069...8,954,738
Ensembl chr23:8,938,906...8,952,808
JBrowse link
G DCC DCC netrin 1 receptor ISO RGD PMID:16337279 RGD:2314374 NCBI chr 1:21,788,833...22,494,849
Ensembl chr 1:21,793,328...22,494,967
JBrowse link
G DHODH dihydroorotate dehydrogenase (quinone) treatment ISO RGD PMID:11522581 RGD:11040446 NCBI chr 5:77,756,411...77,766,207
Ensembl chr 5:77,756,407...77,774,090
JBrowse link
G EPAS1 endothelial PAS domain protein 1 ISO RGD PMID:23603807 RGD:10395381 NCBI chr10:48,550,836...48,636,776
Ensembl chr10:48,551,410...48,634,844
JBrowse link
G EPO erythropoietin ISO RGD PMID:20361946 RGD:10400894 NCBI chr 6:8,994,211...8,995,954
Ensembl chr 6:8,994,211...8,996,144
JBrowse link
G FOXP3 forkhead box P3 ISO protein:decreased expression:sciatic nerve RGD PMID:30464413 RGD:38549576 NCBI chr  X:42,331,229...42,362,841
Ensembl chr  X:42,344,108...42,350,758
JBrowse link
G HAVCR2 hepatitis A virus cellular receptor 2 disease_progression ISO mRNA,protein:increased expression:sciatic nerve: RGD PMID:21784136 RGD:9686114 NCBI chr 4:53,018,990...53,032,035
Ensembl chr 4:53,012,234...53,033,393
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha ISO RGD PMID:23603807 RGD:10395381 NCBI chr 8:36,614,045...36,656,692
Ensembl chr 8:36,614,045...36,656,692
JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase disease_progression ISO RGD PMID:17286627 RGD:5508466 NCBI chr 3:30,970,037...30,988,987
Ensembl chr 3:30,970,037...30,990,294
JBrowse link
G IL17A interleukin 17A ISO mRNA, protein:increased expression:sciatic nerve, inguinal lymph node RGD PMID:10785455 PMID:19207263 RGD:4831923 RGD:4888513 NCBI chr12:19,854,129...19,862,521
Ensembl chr12:19,854,129...19,862,513
JBrowse link
G IL1B interleukin 1 beta treatment ISO RGD PMID:18400050 RGD:7401218 NCBI chr17:37,019,329...37,033,388
Ensembl chr17:37,019,329...37,024,458
JBrowse link
G IL5 interleukin 5 treatment ISO RGD PMID:22310911 RGD:11522768 NCBI chr11:20,825,469...20,827,269
Ensembl chr11:20,825,469...20,827,269
JBrowse link
G MMP7 matrix metallopeptidase 7 ISO RGD PMID:9546322 RGD:9685357 NCBI chr 5:29,187,902...29,196,157
Ensembl chr 5:29,187,851...29,196,153
JBrowse link
G MMP9 matrix metallopeptidase 9 ISO RGD PMID:9546322 RGD:9685357 NCBI chr24:33,274,260...33,281,116
Ensembl chr24:33,274,268...33,281,293