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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Choroidal Neovascularization, Experimental
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Accession:DOID:9006151 term browser browse the term
Definition:Choroidal neovascularization that is induced in experimental animals by use of laser, hypoxia, or chemical injury.
Synonyms:primary_id: RDO:9000349
For additional species annotation, visit the Alliance of Genome Resources.



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Choroidal Neovascularization, Experimental term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Serpine1 serpin family E member 1 severity
treatment
ISO
IDA
mRNA:increased expression:retina (mouse)
human gene in mouse model
RGD PMID:12766088 PMID:12766088 PMID:11292663 PMID:26610445 RGD:8547735, RGD:8547735, RGD:8547737, RGD:11073722 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Smo smoothened, frizzled class receptor treatment IMP RGD PMID:21063852 RGD:12859045 NCBI chr 4:58,344,101...58,372,828
Ensembl chr 4:58,343,529...58,373,829
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 18133
    Animal Diseases 1692
      Animal Disease Models 1640
        Choroidal Neovascularization, Experimental 2
Path 2
Term Annotations click to browse term
  disease 18133
    disease of anatomical entity 17503
      nervous system disease 13174
        sensory system disease 6388
          eye disease 2927
            uveal disease 232
              choroid disease 58
                Choroidal Neovascularization 41
                  Choroidal Neovascularization, Experimental 2
paths to the root