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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Sheep Diseases
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Accession:DOID:9006097 term browser browse the term
Definition:Diseases of domestic and mountain sheep of the genus Ovis.
Synonyms:exact_synonym: Ovine Disease;   Ovine Diseases;   Sheep Disease
 primary_id: MESH:D012757


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scrapie term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF6 activating transcription factor 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23349890 NCBI chr 1:161,766,320...161,964,070
Ensembl chr 1:161,766,298...161,977,574 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator ISO RGD PMID:27921253 RGD:13782156 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G CASP3 caspase 3 ISO RGD PMID:27921253 RGD:13782156 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP9 caspase 9 ISO RGD PMID:27921253 RGD:13782156 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 ISO RGD PMID:22787236 RGD:13782158 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793 		JBrowse link
G CCR1 C-C motif chemokine receptor 1 ISO RGD PMID:18396336 RGD:5688145 NCBI chr 3:46,201,711...46,208,313
Ensembl chr 3:46,201,711...46,208,313 		JBrowse link
G CR2 complement C3d receptor 2 ISO RGD PMID:29202042 RGD:127285805 NCBI chr 1:207,454,328...207,489,892
Ensembl chr 1:207,453,024...207,489,895 		JBrowse link
G JAK2 Janus kinase 2 ISO protein:increased expression:brain RGD PMID:17897356 RGD:6483034 NCBI chr 9:4,984,390...5,129,948
Ensembl chr 9:4,984,390...5,129,948 		JBrowse link
G MIR146A microRNA 146a ISO miRNA:increased expression:brain, hippocampus, cerebellum (mouse) RGD PMID:22363497 RGD:126925151 NCBI chr 5:160,485,352...160,485,450
Ensembl chr 5:160,485,352...160,485,450 		JBrowse link
G NEGR1 neuronal growth regulator 1 ISO RGD PMID:29087046 RGD:40886276 NCBI chr 1:71,395,943...72,282,539
Ensembl chr 1:71,395,943...72,282,539 		JBrowse link
G PDIA3 protein disulfide isomerase family A member 3 ISO protein:increased expression:brain: RGD PMID:15772339 RGD:9999196 NCBI chr15:43,746,438...43,773,278
Ensembl chr15:43,746,394...43,773,279 		JBrowse link
G PRNP prion protein (Kanno blood group) onset EXP
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:11701772 PMID:18717736 PMID:19486493 PMID:21533749 PMID:29157304 RGD:15045596 NCBI chr20:4,686,456...4,701,588
Ensembl chr20:4,686,350...4,701,590 		JBrowse link
G SLC6A4 solute carrier family 6 member 4 susceptibility ISO RGD PMID:16730863 RGD:38676483 NCBI chr17:30,194,319...30,235,697
Ensembl chr17:30,194,319...30,236,002 		JBrowse link
G SOD1 superoxide dismutase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:11701772 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931 		JBrowse link
G SPP1 secreted phosphoprotein 1 ISO RGD PMID:16412998 RGD:1581331 NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532 		JBrowse link
G STAT1 signal transducer and activator of transcription 1 ISO protein:increased expression:brain RGD PMID:17897356 RGD:6483034 NCBI chr 2:190,969,149...191,014,171
Ensembl chr 2:190,908,460...191,020,960 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 ISO protein:increased tyrosine phosphorylation:brain, nucleus RGD PMID:17897356 RGD:6483034 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 121159
    Animal Diseases 1459
      Sheep Diseases 17
        Bluetongue 0
        Border Disease 0
        Nairobi Sheep Disease 0
        Ovine Pulmonary Adenomatosis 0
        Progressive Interstitial Pneumonia of Sheep 0
        Visna 0
        contagious pustular dermatitis 0
        copper deficiency myelopathy 0
        louping ill 0
        scrapie 17
paths to the root