RGD DISEASE ONTOLOGY - ANNOTATIONS
RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term: Pleural Effusion
Accession: DOID:9005883
browse the term
Definition: Presence of fluid in the pleural cavity resulting from excessive transudation or exudation from the pleural surfaces. It is a sign of disease and not a diagnosis in itself.
Synonyms: exact_synonym: Pleural Effusions
primary_id: MESH:D010996 ; RDO:0006358
xref: EFO:0009637
GViewer not supported for the selected species.
G
Ace2
angiotensin converting enzyme 2
ISO
associated with tuberculosis;protein:decreased activity:pleural fluid (human)
RGD
PMID:23091417
RGD:40818411
NCBI chrNW_004955519:2,591,229...2,643,705
Ensembl chrNW_004955519:2,591,248...2,633,495
G
Ada
adenosine deaminase
treatment
ISO
RGD
PMID:25547995
RGD:152995274
NCBI chrNW_004955445:12,696,096...12,717,488
Ensembl chrNW_004955445:12,696,096...12,717,488
G
Chrna1
cholinergic receptor nicotinic alpha 1 subunit
ISO
ClinVar Annotator: match by term: Pleural effusion
ClinVar
PMID:25741868 PMID:28492532 PMID:30177536 PMID:31680349 PMID:36634413
NCBI chrNW_004955449:661,310...683,873
Ensembl chrNW_004955449:661,304...683,873
G
Il15
interleukin 15
ISO
RGD
PMID:15072171
RGD:4990458
NCBI chrNW_004955471:1,496,352...1,583,919
Ensembl chrNW_004955471:1,497,483...1,511,469
G
Lox
lysyl oxidase
ISO
ClinVar Annotator: match by term: Pleural effusion
ClinVar
PMID:25741868 PMID:28492532
NCBI chrNW_004955521:178,290...193,926
Ensembl chrNW_004955521:185,792...193,926
G
Srfbp1
serum response factor binding protein 1
ISO
ClinVar Annotator: match by term: Pleural effusion
ClinVar
PMID:25741868 PMID:28492532
NCBI chrNW_004955521:105,565...160,906
Ensembl chrNW_004955521:104,918...159,724
G
Tnf
tumor necrosis factor
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:2518282
NCBI chrNW_004955437:117,267...119,899
Ensembl chrNW_004955437:117,206...120,700
G
Ada
adenosine deaminase
disease_progression
ISO
protein:decreased expression:serum: protein:increased activity:serum:
RGD
PMID:1689629 PMID:1818842 PMID:27300446
RGD:152995272 RGD:152995292 RGD:152998934
NCBI chrNW_004955445:12,696,096...12,717,488
Ensembl chrNW_004955445:12,696,096...12,717,488
G
Il10
interleukin 10
ISO
RGD
PMID:30695099
RGD:14975123
NCBI chrNW_004955406:42,307,789...42,312,255
Ensembl chrNW_004955406:42,307,664...42,312,779
G
Mmp2
matrix metallopeptidase 2
ISO
associated with pleurisy; protein:decreased activity:pleura
RGD
PMID:17611666
RGD:5130711
NCBI chrNW_004955433:13,024,844...13,050,041
Ensembl chrNW_004955433:13,024,418...13,052,775
G
Mmp9
matrix metallopeptidase 9
ISO
associated with pleurisy; protein:decreased activity:pleura
RGD
PMID:17611666
RGD:5130711
NCBI chrNW_004955445:11,295,500...11,303,322
Ensembl chrNW_004955445:11,295,448...11,303,288
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all