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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Spine Osteoarthritis
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Accession:DOID:9005882 term browser browse the term
Definition:A degenerative joint disease involving the SPINE. It is characterized by progressive deterioration of the spinal articular cartilage (CARTILAGE, ARTICULAR), usually with hardening of the subchondral bone and outgrowth of bone spurs (OSTEOPHYTE).
Synonyms:exact_synonym: Lumbar Osteoarthritis;   Spinal Osteoarthritis
 primary_id: MESH:D055013
 alt_id: RDO:0007695
For additional species annotation, visit the Alliance of Genome Resources.


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Spine Osteoarthritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrp5 LDL receptor related protein 5 susceptibility ISO DNA:polymorphism:cds:p.Q89R(human) RGD PMID:17202888 RGD:12792278 NCBI chr 1:200,814,247...200,917,581
Ensembl chr 1:200,814,250...200,917,581
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Term paths to the root
Path 1
Term Annotations click to browse term
  disease 17208
    Diseases of the Aged 1289
      osteoarthritis 238
        Spine Osteoarthritis 1
Path 2
Term Annotations click to browse term
  disease 17208
    disease of anatomical entity 16554
      musculoskeletal system disease 6417
        connective tissue disease 4421
          bone disease 3108
            bone inflammation disease 963
              arthropathy 73
                spondyloarthropathy 63
                  spondylitis 40
                    Spondylarthritis 6
                      Spine Osteoarthritis 1
paths to the root