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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Periodontal Atrophy
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Accession:DOID:9005858 term browser browse the term
Definition:Degradation or wasting of the PERIODONTIUM tissues that may involve the gum (GINGIVA), the alveolar bone (ALVEOLAR PROCESS), the DENTAL CEMENTUM, or the PERIODONTAL LIGAMENT.
Synonyms:exact_synonym: Atrophy of Periodontium;   Gingivo Osseous Atrophy;   Gingivo-Osseous Atrophies;   Periodontal Atrophies;   Periodontium Atrophies;   Periodontium Atrophy
 primary_id: MESH:D055093;   RDO:0005672
For additional species annotation, visit the Alliance of Genome Resources.


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Periodontal Atrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Vegfa vascular endothelial growth factor A ISO protein:decreased expression:maxilla: RGD PMID:22716278 RGD:7421608 NCBI chrNW_004936476:16,245,134...16,261,180 JBrowse link
Alveolar Bone Loss term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alpl alkaline phosphatase, biomineralization associated ISO CTD Direct Evidence: marker/mechanism CTD PMID:20630305 NCBI chrNW_004936474:7,209,196...7,229,899 JBrowse link
G Il10 interleukin 10 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:26270535 RGD:11049527 NCBI chrNW_004936557:5,834,874...5,838,502 JBrowse link
G Parp1 poly(ADP-ribose) polymerase 1 ISO RGD PMID:14630900 RGD:10413909 NCBI chrNW_004936526:3,102,468...3,147,601 JBrowse link
G Tnf tumor necrosis factor treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:26270535 RGD:11049527 NCBI chrNW_004936727:1,936,066...1,937,766 JBrowse link
G Tnfsf11 TNF superfamily member 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19249596 NCBI chrNW_004936747:1,255,803...1,288,252 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 12955
    Stomatognathic Diseases 894
      tooth disease 264
        periodontal disease 102
          Periodontal Atrophy 6
            Alveolar Bone Loss 5
            Periodontal Attachment Loss 0
            gingival recession 0
Path 2
Term Annotations click to browse term
  disease 12955
    disease of anatomical entity 12628
      nervous system disease 10533
        sensory system disease 4951
          mouth disease 681
            tooth disease 264
              periodontal disease 102
                Periodontal Atrophy 6
                  Alveolar Bone Loss 5
                  Periodontal Attachment Loss 0
                  gingival recession 0
paths to the root