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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Periodontal Atrophy
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Accession:DOID:9005858 term browser browse the term
Definition:Degradation or wasting of the PERIODONTIUM tissues that may involve the gum (GINGIVA), the alveolar bone (ALVEOLAR PROCESS), the DENTAL CEMENTUM, or the PERIODONTAL LIGAMENT.
Synonyms:exact_synonym: Atrophy of Periodontium;   Gingivo Osseous Atrophy;   Gingivo-Osseous Atrophies;   Periodontal Atrophies;   Periodontium Atrophies;   Periodontium Atrophy
 primary_id: MESH:D055093;   RDO:0005672
For additional species annotation, visit the Alliance of Genome Resources.


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Periodontal Atrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Vegfa vascular endothelial growth factor A ISO protein:decreased expression:maxilla: RGD PMID:22716278 RGD:7421608 NCBI chr17:46,016,993...46,032,377
Ensembl chr17:46,016,993...46,032,369
JBrowse link
Alveolar Bone Loss term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alpl alkaline phosphatase, liver/bone/kidney ISO CTD Direct Evidence: marker/mechanism CTD PMID:20630305 NCBI chr 4:137,741,731...137,796,384
Ensembl chr 4:137,741,733...137,796,384
JBrowse link
G Ccr2 chemokine (C-C motif) receptor 2 IMP associated with Periodontitis; RGD PMID:21241302 RGD:8661687 NCBI chr 9:124,101,918...124,109,140
Ensembl chr 9:124,101,950...124,113,557
JBrowse link
G Il10 interleukin 10 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:26270535 RGD:11049527 NCBI chr 1:131,019,845...131,024,970
Ensembl chr 1:131,019,845...131,024,974
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 IMP RGD PMID:14630900 RGD:10413909 NCBI chr 1:180,568,891...180,600,999
Ensembl chr 1:180,568,924...180,601,254
JBrowse link
G Tnf tumor necrosis factor treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:26270535 RGD:11049527 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
G Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19249596 NCBI chr14:78,277,446...78,308,043
Ensembl chr14:78,277,445...78,308,043
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14460
    Stomatognathic Diseases 987
      tooth disease 288
        periodontal disease 117
          Periodontal Atrophy 7
            Alveolar Bone Loss 6
            Periodontal Attachment Loss 0
            gingival recession 0
Path 2
Term Annotations click to browse term
  disease 14460
    disease of anatomical entity 14052
      nervous system disease 11608
        sensory system disease 5411
          mouth disease 760
            tooth disease 288
              periodontal disease 117
                Periodontal Atrophy 7
                  Alveolar Bone Loss 6
                  Periodontal Attachment Loss 0
                  gingival recession 0
paths to the root