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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Periodontal Atrophy
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Accession:DOID:9005858 term browser browse the term
Definition:Degradation or wasting of the PERIODONTIUM tissues that may involve the gum (GINGIVA), the alveolar bone (ALVEOLAR PROCESS), the DENTAL CEMENTUM, or the PERIODONTAL LIGAMENT.
Synonyms:exact_synonym: Atrophy of Periodontium;   Gingivo Osseous Atrophy;   Gingivo-Osseous Atrophies;   Periodontal Atrophies;   Periodontium Atrophies;   Periodontium Atrophy
 primary_id: MESH:D055093;   RDO:0005672
For additional species annotation, visit the Alliance of Genome Resources.


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Periodontal Atrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G VEGFA vascular endothelial growth factor A ISO protein:decreased expression:maxilla: RGD PMID:22716278 RGD:7421608 NCBI chr 6:43,361,053...43,377,366
Ensembl chr 6:44,650,365...44,666,353
JBrowse link
Alveolar Bone Loss term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALPL alkaline phosphatase, biomineralization associated ISO CTD Direct Evidence: marker/mechanism CTD PMID:20630305 NCBI chr 1:20,702,509...20,772,301
Ensembl chr 1:21,667,732...21,736,688
JBrowse link
G CCR2 C-C motif chemokine receptor 2 ISO associated with Periodontitis; RGD PMID:21241302 RGD:8661687 NCBI chr 3:46,255,725...46,263,285
Ensembl chr 3:47,361,124...47,368,312
JBrowse link
G IL10 interleukin 10 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:26270535 RGD:11049527 NCBI chr 1:182,369,234...182,374,207
Ensembl chr 1:186,648,289...186,653,371
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 ISO RGD PMID:14630900 RGD:10413909 NCBI chr 1:201,820,355...201,867,673
Ensembl chr 1:206,812,981...206,860,356
JBrowse link
G TNF tumor necrosis factor treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:26270535 RGD:11049527 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381
JBrowse link
G TNFSF11 TNF superfamily member 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19249596 NCBI chr13:23,750,835...23,784,740 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 13787
    Stomatognathic Diseases 928
      tooth disease 279
        periodontal disease 109
          Periodontal Atrophy 7
            Alveolar Bone Loss 6
            Periodontal Attachment Loss 0
            gingival recession 0
Path 2
Term Annotations click to browse term
  disease 13787
    disease of anatomical entity 13439
      nervous system disease 11176
        sensory system disease 5145
          mouth disease 710
            tooth disease 279
              periodontal disease 109
                Periodontal Atrophy 7
                  Alveolar Bone Loss 6
                  Periodontal Attachment Loss 0
                  gingival recession 0
paths to the root