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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Serum Sickness
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Accession:DOID:9005818 term browser browse the term
Definition:Immune complex disease caused by the administration of foreign serum or serum proteins and characterized by fever, lymphadenopathy, arthralgia, and urticaria. When they are complexed to protein carriers, some drugs can also cause serum sickness when they act as haptens inducing antibody responses.
Synonyms:exact_synonym: Serum Sicknesses
 primary_id: MESH:D012713;   RDO:0006553
For additional species annotation, visit the Alliance of Genome Resources.



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Serum Sickness term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALB albumin ISO CTD Direct Evidence: marker/mechanism CTD PMID:350256 PMID:9380243 NCBI chr 8:69,643,427...69,663,152
Ensembl chr 8:69,531,487...69,721,696
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Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14396
    disease of anatomical entity 14114
      immune system disease 3941
        hypersensitivity reaction disease 146
          hypersensitivity reaction type III disease 25
            Serum Sickness 1
Path 2
Term Annotations click to browse term
  disease 14396
    disease of anatomical entity 14114
      Immune & Inflammatory Diseases 4502
        immune system disease 3941
          allergic disease 553
            drug allergy 104
              Drug Eruptions 67
                Serum Sickness 1
paths to the root