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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Experimental Diabetes Mellitus
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Accession:DOID:9005643 term browser browse the term
Definition:Diabetes mellitus induced experimentally by administration of various diabetogenic agents or by PANCREATECTOMY.
Synonyms:exact_synonym: Alloxan Diabetes;   Experimental Diabetes Mellitus;   Streptozocin Diabete;   streptozocin diabetes;   streptozotocin diabetes
 primary_id: MESH:D003921

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Experimental Diabetes Mellitus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AACS acetoacetyl-CoA synthetase ISO protein:decreased activity:liver RGD PMID:12034369 RGD:2301022 NCBI chr11:120,422,138...120,502,200
Ensembl chr11:120,422,232...120,502,271 		JBrowse link
G AANAT aralkylamine N-acetyltransferase ISO RGD PMID:18624957 RGD:2301030 NCBI chr16:45,206,233...45,215,761
Ensembl chr16:45,206,377...45,207,591 		JBrowse link
G ABAT 4-aminobutyrate aminotransferase ISO RGD PMID:9846053 RGD:1598518 NCBI chr 5:8,274,310...8,380,973
Ensembl chr 5:8,315,952...8,379,549 		JBrowse link
G ABCB1 ATP binding cassette subfamily B member 1 disease_progression
treatment		 ISO mRNA:increased expression:brain
mRNA:increased expression:ileum, intestinal mucosa (rat)
protein: decreased expression		 RGD PMID:17074306 PMID:17664251 PMID:21685928 PMID:26460146 RGD:11041112 RGD:1598559 RGD:2312730 RGD:8657121 NCBI chr21:61,211,044...61,430,691
Ensembl chr21:61,322,748...61,529,274 		JBrowse link
G ABCB4 ATP binding cassette subfamily B member 4 ISO RGD PMID:12055592 RGD:1598588 NCBI chr21:61,459,344...61,529,017 JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 ISO mRNA:decreased expression:liver
protein: increased expression
mRNA: increased expression: brain		 RGD PMID:17664251 PMID:19356064 PMID:20487213 RGD:11541075 RGD:2312728 RGD:2312730 NCBI chr 9:92,826,423...92,902,389
Ensembl chr 9:92,841,818...92,902,265 		JBrowse link
G ABCC3 ATP binding cassette subfamily C member 3 ISO mRNA:increased expression:liver RGD PMID:20487213 RGD:11541075 NCBI chr16:42,646,316...42,703,124
Ensembl chr16:42,646,812...42,702,852 		JBrowse link
G ABCC9 ATP binding cassette subfamily C member 9 ISO mRNA, protein:decreased expression:heart RGD PMID:22257425 RGD:12792003 NCBI chr11:21,658,804...21,797,851
Ensembl chr11:21,658,794...21,797,263 		JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) ISO protein:decreased expression:cerebral cortex RGD PMID:17915193 RGD:2315584 NCBI chr 7:36,458,110...36,599,753 JBrowse link
G ABCG5 ATP binding cassette subfamily G member 5 ISO RGD PMID:14618236 RGD:1558629 NCBI chr14:63,414,241...63,439,193
Ensembl chr14:63,413,691...63,438,917 		JBrowse link
G ABCG8 ATP binding cassette subfamily G member 8 ISO RGD PMID:14618236 RGD:1558629 NCBI chr14:63,389,817...63,420,048
Ensembl chr14:63,390,433...63,413,906 		JBrowse link
G ACAA1 acetyl-CoA acyltransferase 1 ISO mRNA:increased expression:heart RGD PMID:17632588 RGD:2313044 NCBI chr15:1,282,556...1,297,154
Ensembl chr15:1,282,650...1,297,832 		JBrowse link
G ACADVL acyl-CoA dehydrogenase very long chain ISO protein:decreased expression:brain RGD PMID:25260493 RGD:10047114 NCBI chr16:6,593,288...6,598,980
Ensembl chr16:6,593,287...6,598,979 		JBrowse link
G ACE2 angiotensin converting enzyme 2 ISO protein:altered expression:kidney RGD PMID:18679036 RGD:2313799 NCBI chr  X:14,032,231...14,094,163
Ensembl chr  X:14,030,233...14,077,785 		JBrowse link
G ACHE acetylcholinesterase (Cartwright blood group) treatment ISO protein:increased expression:blood RGD PMID:1385785 PMID:19296211 PMID:19303406 PMID:19347982 RGD:150517552 RGD:2312430 RGD:2312432 RGD:2312437 NCBI chr28:12,328,304...12,335,302
Ensembl chr28:12,331,039...12,335,076 		JBrowse link
G ACMSD aminocarboxymuconate semialdehyde decarboxylase treatment ISO RGD PMID:12042425 PMID:19169727 RGD:13831125 RGD:13831126 NCBI chr10:19,063,731...19,128,387
Ensembl chr10:19,064,115...19,129,089 		JBrowse link
G ACOX1 acyl-CoA oxidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14563825 NCBI chr16:45,706,009...45,745,564
Ensembl chr16:45,706,360...45,740,247 		JBrowse link
G ACP5 acid phosphatase 5, tartrate resistant ISO protein:increased activity:femoral bone (rat) RGD PMID:19699734 RGD:2315882 NCBI chr 6:10,488,572...10,493,508
Ensembl chr 6:10,488,460...10,491,519 		JBrowse link
G ACSL1 acyl-CoA synthetase long chain family member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:9452481 NCBI chr 7:130,712,633...130,783,360
Ensembl chr 7:130,712,308...130,763,756 		JBrowse link
G ACSL3 acyl-CoA synthetase long chain family member 3 ISO RGD PMID:21136146 RGD:13831298 NCBI chr10:108,787,341...108,867,523
Ensembl chr10:108,787,061...108,869,042 		JBrowse link
G ACSL6 acyl-CoA synthetase long chain family member 6 ISO mRNA:decreased expression:heart RGD PMID:16428347 RGD:1599808 NCBI chr23:34,787,097...34,846,387
Ensembl chr23:34,787,432...34,829,042 		JBrowse link
G ADA adenosine deaminase ISO protein:increased expression:platelet RGD PMID:9784839 PMID:19166862 RGD:2313538 RGD:2313540 NCBI chr 2:19,167,209...19,200,233 JBrowse link
G ADCYAP1 adenylate cyclase activating polypeptide 1 ISO protein:increased expression:pancreas, hypothalamus RGD PMID:9864055 RGD:2325314 NCBI chr18:60,259,479...60,267,302 JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing ISO protein:increased expression:retina
mRNA, protein:decreased expression:adipose tissue, serum		 RGD PMID:16201273 PMID:23174569 RGD:1599146 RGD:8694416 NCBI chr15:81,128,427...81,142,779
Ensembl chr15:81,129,795...81,147,391 		JBrowse link
G ADIPOR2 adiponectin receptor 2 no_association ISO Reduced Adipor2 mRNA in livers of diabetic mice RGD PMID:17884446 PMID:18222103 PMID:19220660 RGD:2312478 RGD:2312488 RGD:2312495 NCBI chr11:1,802,694...1,836,703
Ensembl chr11:1,738,026...1,837,060 		JBrowse link
G ADK adenosine kinase ISO protein:decreased expression:spleen, lymphocyte RGD PMID:12729803 RGD:2313360 NCBI chr 9:56,659,284...57,222,279
Ensembl chr 9:56,660,129...57,222,147 		JBrowse link
G ADM adrenomedullin ISO protein:increased expression:pigmented epithelial cell, retina RGD PMID:16955796 RGD:1625296 NCBI chr 1:54,518,359...54,520,683
Ensembl chr 1:54,518,358...54,520,686 		JBrowse link
G ADORA1 adenosine A1 receptor treatment ISO protein:decreased expression:hippocampus
associated with hypertension		 RGD PMID:9597368 PMID:11593763 PMID:16256246 PMID:19276628 RGD:1625365 RGD:2313804 RGD:2313805 RGD:2313808 NCBI chr25:26,180,898...26,221,424
Ensembl chr25:26,182,446...26,220,776 		JBrowse link
G ADORA2A adenosine A2a receptor ISO protein:increased expression:hippocampus RGD PMID:16256246 RGD:2313805 NCBI chr19:7,691,678...7,706,781
Ensembl chr19:7,691,536...7,706,926 		JBrowse link
G ADRA1A adrenoceptor alpha 1A ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:17054657 PMID:19133277 RGD:1625775 NCBI chr 8:24,884,187...24,985,824
Ensembl chr 8:24,885,741...24,983,125 		JBrowse link
G ADRB1 adrenoceptor beta 1 ISO protein:decreased expression:left ventricle muscular part RGD PMID:21054861 RGD:5129115 NCBI chr 9:106,920,520...106,923,424
Ensembl chr 9:106,920,610...106,922,058 		JBrowse link
G ADRB3 adrenoceptor beta 3 ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:left ventricle muscular part		 CTD
RGD		 PMID:17622774 PMID:21054861 RGD:5129115 NCBI chr 8:35,993,553...35,998,200
Ensembl chr 8:35,994,775...35,997,060 		JBrowse link
G ADSL adenylosuccinate lyase ISO protein:increased activity:heart (rat) RGD PMID:3360219 RGD:1598762 NCBI chr19:22,920,971...22,940,468 JBrowse link
G ADSS1 adenylosuccinate synthase 1 ISO protein:increased activity:heart (rat) RGD PMID:3360219 RGD:1598762 NCBI chr24:82,662,232...82,684,690
Ensembl chr24:82,662,319...82,684,874 		JBrowse link
G AGER advanced glycosylation end-product specific receptor treatment ISO mRNA:increased expression:renal cortex (mouse)
protein:increased expression:lacrimal gland		 RGD PMID:16283249 PMID:20801062 PMID:21458563 PMID:22476978 PMID:34018385 RGD:1625335 RGD:597621665 RGD:7243964 RGD:7244188 RGD:7245558 NCBI chr17:39,847,343...39,851,288
Ensembl chr17:39,847,759...39,851,127 		JBrowse link
G AGT angiotensinogen ISO CTD Direct Evidence: marker/mechanism CTD PMID:15831366 PMID:17177138 PMID:18829990 NCBI chr25:67,964,840...67,977,006
Ensembl chr25:67,962,401...67,973,324 		JBrowse link
G AGTR2 angiotensin II receptor type 2 ISO mRNA, protein:decreased expression:kidney RGD PMID:12172324 RGD:6903861
G AIFM1 apoptosis inducing factor mitochondria associated 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23499715 NCBI chr  X:105,383,408...105,419,146
Ensembl chr  X:105,382,693...105,419,095 		JBrowse link
G AIRE autoimmune regulator susceptibility ISO RGD PMID:18399912 RGD:2306853 NCBI chr 2:88,019,122...88,031,998
Ensembl chr 2:88,019,522...88,031,801 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 treatment ISO protein:increased serine phosphorylation:cortex of kidney
protein:decreased serine phosphorylation:cornea		 RGD PMID:18599524 PMID:21330660 PMID:29379801 RGD:408346751 RGD:5131482 RGD:8657153 NCBI chr24:82,704,087...82,730,711
Ensembl chr24:82,704,068...82,727,698 		JBrowse link
G ALAD aminolevulinate dehydratase treatment
susceptibility		 ISO protein:decreased activity:liver, erythrocyte (rat)
protein:decreased activity:liver, kidney (rat)
protein:decreased activity:blood, liver		 RGD PMID:7728901 PMID:10224671 PMID:18668330 PMID:19043199 PMID:21864646 More... RGD:12904683 RGD:12904692 RGD:12904702 RGD:12904704 RGD:15039405 RGD:4144150 NCBI chr12:26,173,063...26,185,456
Ensembl chr12:26,173,096...26,189,845 		JBrowse link
G ALAS1 5'-aminolevulinate synthase 1 ISO protein:decreased activity:liver (rat) RGD PMID:6688350 RGD:4144808 NCBI chr22:13,558,011...13,573,740
Ensembl chr22:13,559,180...13,575,869 		JBrowse link
G ALDOB aldolase, fructose-bisphosphate B ISO mRNA:reduced expression:liver, small intestine (rat) RGD PMID:2984252 RGD:2313437 NCBI chr12:37,993,367...38,021,693
Ensembl chr12:38,007,265...38,021,258 		JBrowse link
G ANGPT1 angiopoietin 1 ISO protein:increased expression:retina RGD PMID:15047628 PMID:17294737 RGD:1626163 RGD:2313817 NCBI chr 8:102,020,346...102,268,443 JBrowse link
G ANGPT2 angiopoietin 2 ISO protein:increased expression:retina RGD PMID:15047628 RGD:2313817 NCBI chr 8:6,283,619...6,345,320
Ensembl chr 8:6,280,584...6,344,729 		JBrowse link
G ANGPTL3 angiopoietin like 3 ISO protein:increased expression:liver RGD PMID:15094378 RGD:2314234 NCBI chr20:70,452,771...70,461,590
Ensembl chr20:70,449,227...70,460,469 		JBrowse link
G ANXA1 annexin A1 ISO protein:increased glycation:respiratory system blood vessel endothelium RGD PMID:11423489 RGD:2306888 NCBI chr12:84,207,818...84,226,438
Ensembl chr12:84,207,820...84,226,562 		JBrowse link
G ANXA2 annexin A2 ISO protein:increased glycation:respiratory system blood vessel endothelium RGD PMID:11423489 RGD:2306888 NCBI chr26:23,100,000...23,147,687
Ensembl chr26:23,099,992...23,145,457 		JBrowse link
G AOC1 amine oxidase copper containing 1 ISO RGD PMID:1632778 RGD:2312809 NCBI chr21:119,037,498...119,046,875
Ensembl chr21:119,038,356...119,047,279 		JBrowse link
G AOC3 amine oxidase copper containing 3 ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:kidney, serum		 RGD
CTD		 PMID:2218072 PMID:12606817 PMID:14977883 PMID:19635478 RGD:2313819 RGD:2313824 RGD:2313828 NCBI chr16:63,435,494...63,442,790
Ensembl chr16:63,437,067...63,442,256 		JBrowse link
G APOA1 apolipoprotein A1 treatment ISO RGD PMID:17488882 RGD:7241577 NCBI chr 1:108,201,967...108,203,902
Ensembl chr 1:108,201,439...108,203,609 		JBrowse link
G APOB apolipoprotein B ISO RGD PMID:17292734 RGD:1642185 NCBI chr14:86,624,209...86,669,175
Ensembl chr14:86,624,332...86,668,704 		JBrowse link
G APOE apolipoprotein E ISO protein:decreased expression:plasma (rat) RGD PMID:16947119 RGD:1599198 NCBI chr 6:38,377,154...38,381,219
Ensembl chr 6:38,376,887...38,381,438 		JBrowse link
G APOM apolipoprotein M ISO protein:decreased secretion:plasma RGD PMID:16516154 RGD:2314249
G APRT adenine phosphoribosyltransferase ISO protein:decreased activity:mammary gland (rat) RGD PMID:2451510 RGD:1599204 NCBI chr 5:74,196,858...74,199,789
Ensembl chr 5:74,194,013...74,199,891 		JBrowse link
G AQP1 aquaporin 1 (Colton blood group) ISO protein:increased expression:retina RGD PMID:19596320 RGD:2316078 NCBI chr21:27,456,553...27,473,196
Ensembl chr21:27,456,259...27,470,728 		JBrowse link
G AQP2 aquaporin 2 ISO protein:decreased expression:kidney collecting duct
protein:increased expression:Kidney Medulla		 RGD PMID:11380083 PMID:15705184 RGD:2314326 RGD:2314347 NCBI chr11:46,179,783...46,188,631
Ensembl chr11:46,180,387...46,188,712 		JBrowse link
G AQP4 aquaporin 4 ISO mRNA,protein:increased expression:retina: RGD PMID:22449442 RGD:8695996 NCBI chr18:53,729,143...53,742,916
Ensembl chr18:53,729,186...53,743,156 		JBrowse link
G AR androgen receptor treatment ISO protein:decreased expression:pancreatic B cell
mRNA, protein:decreased expression:epididymis, prostate gland, testis		 RGD PMID:16398356 PMID:18543106 PMID:31838605 RGD:2306772 RGD:2306774 RGD:407424618 NCBI chr  X:57,380,587...57,553,613
Ensembl chr  X:57,380,611...57,546,776 		JBrowse link
G ARG1 arginase 1 ISO protein:increased expression:aorta, liver (rat) RGD PMID:17967788 RGD:4142848 NCBI chr13:41,971,955...41,983,372
Ensembl chr13:41,971,802...41,983,049 		JBrowse link
G ARG2 arginase 2 ISO protein:increased activity:kidney (rat) RGD PMID:12841630 RGD:4143269 NCBI chr24:44,851,139...44,884,118
Ensembl chr24:44,851,175...44,883,853 		JBrowse link
G ASPA aspartoacylase ISO protein:increased expression:duodenum, brain RGD PMID:16707098 RGD:1601247 NCBI chr16:2,980,325...3,005,632
Ensembl chr16:2,982,459...3,009,885 		JBrowse link
G ASS1 argininosuccinate synthase 1 ISO mRNA, protein:increased expression:aorta (rat) RGD PMID:11384198 RGD:1599310 NCBI chr12:7,643,484...7,701,334 JBrowse link
G ATF3 activating transcription factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16123366 NCBI chr25:16,910,312...16,922,598 JBrowse link
G ATG7 autophagy related 7 treatment ISO protein:decreased expression:myocardium RGD PMID:24874076 PMID:24993523 RGD:11557993 RGD:11557996 NCBI chr22:47,187,305...47,571,309
Ensembl chr22:47,325,614...47,571,070 		JBrowse link
G ATP2A1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 ISO RGD PMID:28483572 RGD:12910731 NCBI chr 5:26,165,370...26,196,517
Ensembl chr 5:26,164,205...26,193,172 		JBrowse link
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 ISO protein:increased carbonylation:heart
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:16123366 PMID:20122173 PMID:21300842 PMID:28483572 RGD:12910731 RGD:13782130 RGD:6904139 NCBI chr11:105,522,175...105,590,291
Ensembl chr11:105,522,157...105,590,958 		JBrowse link
G ATP2A3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:16123366 PMID:20122173 RGD:13782130 NCBI chr16:3,405,871...3,443,339
Ensembl chr16:3,405,820...3,443,275 		JBrowse link
G ATP4B ATPase H+/K+ transporting subunit beta ISO RGD PMID:20237950 RGD:14696743 NCBI chr 3:91,618,147...91,629,177
Ensembl chr 3:91,618,957...91,627,679 		JBrowse link
G ATP5F1A ATP synthase F1 subunit alpha ISO protein:decreased expression:cerebral cortex, mitochondrion (rat) RGD PMID:28526935 RGD:13703047 NCBI chr18:34,815,924...34,828,052
Ensembl chr18:34,816,027...34,830,924 		JBrowse link
G ATP5F1B ATP synthase F1 subunit beta ISO associated with polycystic ovary syndrome;mRNA, protein:decreased expression:pancreas (rat) RGD PMID:28397049 RGD:13703107 NCBI chr11:52,587,608...52,600,057
Ensembl chr11:52,587,143...52,600,756 		JBrowse link
G ATP5PD ATP synthase peripheral stalk subunit d ISO protein:decreased expression:retina (rat) RGD PMID:17465459 RGD:5147874 NCBI chr16:46,625,512...46,630,613 JBrowse link
G ATP5PF ATP synthase peripheral stalk subunit F6 treatment ISO RGD PMID:28731155 RGD:13800891 NCBI chr 2:66,539,014...66,550,186
Ensembl chr 2:66,538,864...66,550,046 		JBrowse link
G AVP arginine vasopressin ISO mRNA:increased expression:hypothalamus RGD PMID:18420743 RGD:2301919 NCBI chr 2:33,761,066...33,764,608
Ensembl chr 2:33,761,140...33,763,172 		JBrowse link
G BAD BCL2 associated agonist of cell death ISO protein:increased expression, decreased phosphorylation, altered activity:testis
protein:decreased serine phosphorylation:cornea		 RGD PMID:17870134 PMID:21330660 RGD:2292685 RGD:5131482 NCBI chr 1:9,949,717...9,964,433
Ensembl chr 1:9,949,762...9,964,432 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator treatment ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:retina		 RGD
CTD		 PMID:18991018 PMID:23090186 PMID:23267840 RGD:10054099 RGD:2311240 NCBI chr 6:42,186,028...42,193,105 JBrowse link
G BCHE butyrylcholinesterase ISO protein:decreased expression:retina RGD PMID:11478742 PMID:12379509 PMID:16187484 RGD:1599458 RGD:2306781 RGD:2306783 NCBI chr15:23,708,121...23,778,027
Ensembl chr15:23,708,155...23,778,286 		JBrowse link
G BCKDHA branched chain keto acid dehydrogenase E1 subunit alpha ISO protein:increased expression:liver RGD PMID:9460082 RGD:1599467 NCBI chr 6:35,717,679...35,747,245
Ensembl chr 6:35,717,694...35,751,098 		JBrowse link
G BCKDHB branched chain keto acid dehydrogenase E1 subunit beta ISO Protein:increased expression:liver; RGD PMID:9460082 RGD:1599467 NCBI chr13:4,845,481...5,087,558
Ensembl chr13:4,845,457...5,087,745 		JBrowse link
G BCL2 BCL2 apoptosis regulator ISO mRNA:decreased expression:embryo
protein:increased expression:retina
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:15649569 PMID:16959961 PMID:18991018 PMID:23090186 RGD:1599491 RGD:2311240 NCBI chr18:16,440,560...16,643,187
Ensembl chr18:16,441,733...16,637,895 		JBrowse link
G BCL2L1 BCL2 like 1 ISO CTD Direct Evidence: marker/mechanism
protein:decreased expression, altered activity:testis		 CTD
RGD		 PMID:16959961 PMID:17870134 RGD:2292685 NCBI chr 2:36,059,024...36,118,332
Ensembl chr 2:36,058,919...36,116,470 		JBrowse link
G BDH1 3-hydroxybutyrate dehydrogenase 1 ISO protein:decreased activity:heart, mitochondrion (rat) RGD PMID:3548709 RGD:2326100 NCBI chr15:89,678,844...89,741,848
Ensembl chr15:89,707,046...89,742,434 		JBrowse link
G BDKRB1 bradykinin receptor B1 ISO mRNA:increased expression:heart
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:12489796 PMID:12522068 PMID:20092893 PMID:21430409 RGD:704379 RGD:704380 RGD:7241569 NCBI chr24:74,136,464...74,146,668
Ensembl chr24:74,145,531...74,146,592 		JBrowse link
G BDKRB2 bradykinin receptor B2 ISO protein:increased expression:hindbrain, spinal cord
mRNA:increased expression:heart		 RGD PMID:12489796 PMID:16138314 RGD:4890452 RGD:704379 NCBI chr24:74,084,907...74,125,604
Ensembl chr24:74,118,210...74,122,909 		JBrowse link
G BDNF brain derived neurotrophic factor treatment ISO RGD PMID:24857910 PMID:30816461 RGD:10059399 RGD:596936233 NCBI chr 1:37,386,825...37,451,380
Ensembl chr 1:37,449,593...37,450,336 		JBrowse link
G BECN1 beclin 1 treatment ISO RGD PMID:24993523 RGD:11557996 NCBI chr16:63,469,187...63,482,627
Ensembl chr16:63,469,192...63,485,322 		JBrowse link
G BGLAP bone gamma-carboxyglutamate protein ISO protein:reduced expression:serum (rat) RGD PMID:19494718 RGD:2316184 NCBI chr20:7,623,716...7,626,353
Ensembl chr20:7,623,883...7,624,812 		JBrowse link
G BMAL1 basic helix-loop-helix ARNT like 1 ISO RGD PMID:18624957 RGD:2301030 NCBI chr 1:51,430,670...51,540,344
Ensembl chr 1:51,431,180...51,462,674 		JBrowse link
G BMPR2 bone morphogenetic protein receptor type 2 ISO protein:increased expression:lung RGD PMID:21521772 RGD:5135278 NCBI chr10:88,103,442...88,302,578
Ensembl chr10:88,106,072...88,303,734 		JBrowse link
G BTC betacellulin ISO RGD PMID:14988244 PMID:18388935 PMID:19819964 RGD:1357906 RGD:2306965 RGD:2313774 NCBI chr 7:23,283,269...23,333,373
Ensembl chr 7:23,281,862...23,308,287 		JBrowse link
G CACNG4 calcium voltage-gated channel auxiliary subunit gamma 4 ISO mRNA:decreased expression:sinoatrial node: RGD PMID:27096430 RGD:13524560 NCBI chr16:54,413,981...54,482,707
Ensembl chr16:54,413,965...54,482,561 		JBrowse link
G CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase ISO protein:decreased activity:mammary gland (rat) RGD PMID:1476792 RGD:5132591 NCBI chr14:80,371,154...80,399,193
Ensembl chr14:80,371,096...80,398,914 		JBrowse link
G CALD1 caldesmon 1 ISO RGD PMID:10644879 RGD:2314036 NCBI chr21:103,435,238...103,671,901
Ensembl chr21:103,469,975...103,672,699 		JBrowse link
G CAPN10 calpain 10 ISO mRNA, protein:decreased expression:kidney cortex RGD PMID:22568896 RGD:7247732 NCBI chr10:126,613,722...126,626,388 JBrowse link
G CARHSP1 calcium regulated heat stable protein 1 treatment ISO RGD PMID:19997081 RGD:39128203 NCBI chr 5:8,430,827...8,445,486 JBrowse link
G CASP1 caspase 1 ISO mRNA:increased expression:retina RGD PMID:18398369 RGD:2315888 NCBI chr 1:96,389,697...96,400,610
Ensembl chr 1:96,389,657...96,400,849 		JBrowse link
G CASP3 caspase 3 treatment ISO CTD Direct Evidence: marker/mechanism
protein:increased activity:hypothalamus		 CTD
RGD		 PMID:19094082 PMID:20654064 PMID:28843149 RGD:13782300 RGD:2311447 NCBI chr 7:130,589,592...130,610,845
Ensembl chr 7:130,591,166...130,610,899 		JBrowse link
G CASP6 caspase 6 ISO protein:increased activity:heart left ventricle RGD PMID:15662549 RGD:2301316 NCBI chr 7:57,592,632...57,616,094
Ensembl chr 7:57,593,342...57,607,489 		JBrowse link
G CASP8 caspase 8 treatment ISO protein:increased expression, increased activity:pituitary gland
protein:increased activity, increased expression:pituitary gland, prolactin secreting cell		 RGD PMID:15976052 PMID:17563067 PMID:19540304 PMID:28843149 RGD:13782300 RGD:2311319 RGD:2311427 RGD:2311429 NCBI chr10:86,888,654...86,944,159
Ensembl chr10:86,916,527...86,943,829 		JBrowse link
G CASP9 caspase 9 ISO protein:increased activity, increased expression:pituitary gland RGD PMID:15976052 RGD:2311319 NCBI chr20:116,772,819...116,798,402
Ensembl chr20:116,772,155...116,798,930 		JBrowse link
G CASQ1 calsequestrin 1 ISO protein:increased activity:skeletal muscle tissue RGD PMID:11976916 RGD:2314137 NCBI chr20:3,744,921...3,759,220
Ensembl chr20:3,744,780...3,756,435 		JBrowse link
G CASR calcium sensing receptor ISO protein:increased expression:pancreas, liver, kidney (rat) RGD PMID:22844268 RGD:7205442 NCBI chr22:58,579,640...58,612,142
Ensembl chr22:58,578,396...58,604,756 		JBrowse link
G CAT catalase ISO CTD Direct Evidence: marker/mechanism|therapeutic
associated with alcohol use disorder; protein:decreased activity;testis, epididymis (rat)		 CTD
RGD		 PMID:12123627 PMID:15855331 PMID:20376213 PMID:20709041 PMID:25541261 RGD:405255664 RGD:5130772 NCBI chr 1:30,792,533...30,828,920
Ensembl chr 1:30,792,399...30,829,592 		JBrowse link
G CAV1 caveolin 1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:18266981 PMID:25086377 RGD:10045572 NCBI chr21:85,222,724...85,258,562
Ensembl chr21:85,222,879...85,258,627 		JBrowse link
G CAV3 caveolin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18266981 NCBI chr22:44,726,597...44,740,456
Ensembl chr22:44,727,624...44,740,459 		JBrowse link
G CCK cholecystokinin ISO RGD PMID:15536283 RGD:2313638 NCBI chr22:3,698,192...3,705,443
Ensembl chr22:3,698,173...3,704,956 		JBrowse link
G CCKBR cholecystokinin B receptor ISO mRNA, protein:decreased expression:pancreas RGD PMID:15161757 RGD:1358452 NCBI chr 1:58,555,463...58,569,949
Ensembl chr 1:58,555,321...58,568,031 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 treatment ISO protein:increased expression:gingiva
protein:increased expression:plasma		 RGD PMID:16891764 PMID:17876613 PMID:18976114 RGD:2306984 RGD:2306992 RGD:8549535 NCBI chr16:27,763,354...27,765,437
Ensembl chr16:27,763,555...27,765,416 		JBrowse link
G CCL20 C-C motif chemokine ligand 20 ISO CTD Direct Evidence: therapeutic CTD PMID:21340626 NCBI chr10:113,815,099...113,836,562
Ensembl chr10:113,832,573...113,835,736 		JBrowse link
G CCN1 cellular communication network factor 1 ISO mRNA:increased expression:retina (mouse) RGD PMID:22160564 RGD:329845551 NCBI chr20:47,783,270...47,786,216
Ensembl chr20:47,783,935...47,785,997 		JBrowse link
G CCN2 cellular communication network factor 2 treatment ISO mRNA, protein:increased expression:heart, myocardium (rat)
mRNA:increased expression:heart left ventricle (rat)		 RGD PMID:19625611 PMID:19820199 PMID:34018385 RGD:2314021 RGD:2314487 RGD:597621665 NCBI chr13:41,613,838...41,617,010
Ensembl chr13:41,613,798...41,617,651 		JBrowse link
G CCNA2 cyclin A2 ISO RGD PMID:20031167 RGD:2316310 NCBI chr 7:69,092,410...69,100,191
Ensembl chr 7:69,093,543...69,099,497 		JBrowse link
G CCNB1 cyclin B1 ISO mRNA:decreased expression:liver (rat) RGD PMID:20031167 RGD:2316310 NCBI chr 4:65,265,798...65,276,465
Ensembl chr 4:65,265,844...65,277,085 		JBrowse link
G CCND3 cyclin D3 ISO protein:increased expression:kidney, glomerulus RGD PMID:19276076 RGD:2316018 NCBI chr17:30,107,236...30,228,449
Ensembl chr17:30,221,598...30,227,452 		JBrowse link
G CCNT1 cyclin T1 ISO mRNA,protein:decreased expression:liver: RGD PMID:20828602 RGD:9698426 NCBI chr11:44,932,774...44,966,412
Ensembl chr11:44,937,350...44,966,018 		JBrowse link
G CCR5 C-C motif chemokine receptor 5 ISO protein:increased expression:retina RGD PMID:21575160 RGD:11533943 NCBI chr22:7,803,794...7,818,112 JBrowse link
G CD28 CD28 molecule ISO RGD PMID:11160314 RGD:2307200 NCBI chr10:89,471,710...89,505,152
Ensembl chr10:89,471,730...89,500,387 		JBrowse link
G CD36 CD36 molecule (CD36 blood group) treatment ISO mRNA:increased expression:multiple organs RGD PMID:16838191 PMID:23691525 RGD:11041145 RGD:2307214 NCBI chr21:68,214,875...68,309,336
Ensembl chr21:68,216,201...68,268,669 		JBrowse link
G CD3E CD3e molecule ISO RGD PMID:16628253 RGD:2314179 NCBI chr 1:109,681,142...109,692,835
Ensembl chr 1:109,681,065...109,692,839 		JBrowse link
G CD40LG CD40 ligand treatment ISO protein:increased expression:platelet (rat) RGD PMID:19237211 PMID:21831422 RGD:11352661 RGD:2312338 NCBI chr  X:111,655,301...111,667,602
Ensembl chr  X:111,655,397...111,666,639 		JBrowse link
G CD68 CD68 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:20388520 NCBI chr16:6,956,633...6,959,645
Ensembl chr16:6,957,212...6,959,042 		JBrowse link
G CD80 CD80 molecule ISO RGD PMID:11160314 RGD:2307200 NCBI chr22:61,258,281...61,294,772 JBrowse link
G CD86 CD86 molecule ISO RGD PMID:8993020 RGD:2313930 NCBI chr22:58,741,534...58,805,417
Ensembl chr22:58,741,525...58,805,366 		JBrowse link
G CDK9 cyclin dependent kinase 9 ISO mRNA,protein:decreased expression:liver: RGD PMID:20828602 RGD:9698426 NCBI chr12:10,342,240...10,346,792
Ensembl chr12:10,342,801...10,346,502 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A ISO protein:increased expression:testes: RGD PMID:24828139 RGD:8662307 NCBI chr17:35,445,668...35,454,334
Ensembl chr17:35,445,223...35,454,342 		JBrowse link
G CEL carboxyl ester lipase ISO protein:decreased expression:pancreas, RGD PMID:8446851 RGD:2313971 NCBI chr12:5,053,817...5,077,487
Ensembl chr12:5,066,882...5,077,227 		JBrowse link
G CFD complement factor D ISO protein:decreased expression:serum RGD PMID:8372111 RGD:1624344 NCBI chr 6:608,821...612,382
Ensembl chr 6:608,800...613,498 		JBrowse link
G CFTR CF transmembrane conductance regulator severity ISO RGD PMID:16804061 RGD:2314614 NCBI chr21:86,154,313...86,332,436 JBrowse link
G CHAT choline O-acetyltransferase ISO protein:decreased expression:telencephalon RGD PMID:26282349 RGD:402463971 NCBI chr 9:42,159,367...42,216,137
Ensembl chr 9:42,162,601...42,214,705 		JBrowse link
G CHRM2 cholinergic receptor muscarinic 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18603373 NCBI chr21:105,574,879...105,730,265
Ensembl chr21:105,726,175...105,727,575 		JBrowse link
G CLPS colipase ISO RGD PMID:19577003 RGD:2314624 NCBI chr17:36,320,468...36,322,912
Ensembl chr17:36,320,541...36,322,902 		JBrowse link
G CLU clusterin ISO protein:increased expression:retina
protein:increased expression:pancreatic islet		 RGD PMID:12763621 PMID:23351716 RGD:9068392 RGD:9068411 NCBI chr 8:25,704,441...25,721,789
Ensembl chr 8:25,703,257...25,721,789 		JBrowse link
G CMA1 chymase 1 ISO protein:increased expression:mesenteric artery, mast cell (rat) RGD PMID:15337505 RGD:5128799 NCBI chr24:1,471,767...1,475,062
Ensembl chr24:1,471,725...1,474,692 		JBrowse link
G CNR1 cannabinoid receptor 1 ISO protein:increased expression:hypothalamus, striatum RGD PMID:18401837 RGD:2314633 NCBI chr13:12,626,259...12,653,253
Ensembl chr13:12,630,270...12,631,688 		JBrowse link
G COMT catechol-O-methyltransferase ISO protein:decreased expression:liver RGD PMID:12010186 RGD:2289789 NCBI chr19:5,775,829...5,803,260
Ensembl chr19:5,773,225...5,785,422 		JBrowse link
G CPS1 carbamoyl-phosphate synthase 1 ISO protein:increased activity:liver (rat) RGD PMID:2882780 RGD:4144110 NCBI chr10:96,267,890...96,392,393
Ensembl chr10:96,267,889...96,392,206 		JBrowse link
G CPT1A carnitine palmitoyltransferase 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:16123366 NCBI chr 1:5,704,275...5,784,077
Ensembl chr 1:5,730,853...5,784,337 		JBrowse link
G CPT1B carnitine palmitoyltransferase 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:14563825 NCBI chr19:33,044,272...33,055,197
Ensembl chr19:33,043,916...33,054,247 		JBrowse link
G CRH corticotropin releasing hormone ISO mRNA:increased expression:paraventricular hypothalamic nucleus (rat) RGD PMID:9652969 RGD:5508166 NCBI chr 8:62,052,155...62,056,424
Ensembl chr 8:62,052,592...62,053,182 		JBrowse link
G CRP C-reactive protein ISO RGD PMID:21736771 PMID:21736794 RGD:6482316 RGD:6907422 NCBI chr20:4,232,262...4,235,826
Ensembl chr20:4,232,913...4,235,377 		JBrowse link
G CRTC2 CREB regulated transcription coactivator 2 ISO RGD PMID:23595987 RGD:9685169 NCBI chr20:9,853,094...9,864,843
Ensembl chr20:9,853,481...9,865,083 		JBrowse link
G CS citrate synthase ISO protein decreased expression:heart, soleus
protein:increased expression:hippocampus		 RGD PMID:12077722 PMID:21088877 RGD:329337352 RGD:329337354 NCBI chr11:52,224,667...52,253,552
Ensembl chr11:52,222,724...52,253,307 		JBrowse link
G CSF1 colony stimulating factor 1 ISO mRNA,protein:increased expression:retina (rat) RGD PMID:19219684 RGD:151665779 NCBI chr20:23,615,107...23,635,399 JBrowse link
G CSF1R colony stimulating factor 1 receptor ISO mRNA,protein:increased expression:retina (rat) RGD PMID:19219684 RGD:151665779 NCBI chr23:52,663,290...52,723,652
Ensembl chr23:52,664,076...52,697,304 		JBrowse link
G CTSB cathepsin B ISO protein:decreased activity:glomerulus (rat) RGD PMID:10393385 RGD:2315531 NCBI chr 8:7,246,076...7,269,655
Ensembl chr 8:7,246,013...7,268,854 		JBrowse link
G CTSC cathepsin C ISO RGD PMID:148980 RGD:1599652 NCBI chr 1:79,426,556...79,468,464
Ensembl chr 1:79,426,549...79,468,340 		JBrowse link
G CTSL cathepsin L ISO mRNA:increased expression:gastrocnemius muscle (rat) RGD PMID:14718385 RGD:1641826 NCBI chr12:98,347,770...98,353,426
Ensembl chr12:98,347,800...98,353,467 		JBrowse link
G CX3CR1 C-X3-C motif chemokine receptor 1 ISO mRNA:increased expression:kidney RGD PMID:15153757 RGD:4891992 NCBI chr15:136,757...153,316
Ensembl chr15:150,718...151,785 		JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 ISO mRNA:increased expression:pancreatic islet RGD PMID:17372021 RGD:2311360 NCBI chr 7:24,526,657...24,529,193
Ensembl chr 7:24,526,680...24,529,130 		JBrowse link
G CXCL12 C-X-C motif chemokine ligand 12 ISO protein:increased expression:retina RGD PMID:17878289 PMID:18201529 RGD:2306555 RGD:2306557 NCBI chr 9:40,005,580...40,020,513
Ensembl chr 9:40,011,439...40,020,494 		JBrowse link
G CYBB cytochrome b-245 beta chain ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:cerebral cortex;associated with reperfusion injury
mRNA:increased expression:aorta		 CTD
RGD		 PMID:11157681 PMID:15148062 PMID:19478208 RGD:1599683 RGD:1599691
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 ISO mRNA:decreased expression:sciatic nerve (rat) RGD PMID:20826654 RGD:4145530 NCBI chr26:9,122,008...9,151,844 JBrowse link
G CYP11B1 cytochrome P450 family 11 subfamily B member 1 ISO mRNA:increased expression:kidney RGD PMID:18582458 RGD:2307289 NCBI chr 8:137,125,409...137,132,267 JBrowse link
G CYP19A1 cytochrome P450 family 19 subfamily A member 1 ISO protein:decreased expression:ovary, testis (rat) RGD PMID:20428845 RGD:4890359 NCBI chr26:32,074,260...32,164,926
Ensembl chr26:32,132,425...32,164,277 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:liver, microsome (rat)		 CTD
RGD		 PMID:10711628 PMID:22342832 RGD:2307074 NCBI chr26:8,753,236...8,759,378
Ensembl chr26:8,753,327...8,759,384 		JBrowse link
G CYP27B1 cytochrome P450 family 27 subfamily B member 1 ISO RGD PMID:3295473 RGD:2307313 NCBI chr11:53,675,704...53,681,372
Ensembl chr11:53,675,226...53,680,443 		JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22342832 NCBI chr 6:35,392,699...35,418,171
Ensembl chr 6:35,393,342...35,418,106 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 ISO mRNA, protein:increased expression:kidney, liver RGD PMID:12700423 PMID:19406192 RGD:2313683 RGD:2313685 NCBI chr26:53,390,054...53,403,309
Ensembl chr26:53,390,089...53,404,211 		JBrowse link
G DBH dopamine beta-hydroxylase ISO mRNA, protein:increased expression:adrenal gland (rat) RGD PMID:16396986 RGD:5130724 NCBI chr12:4,474,041...4,498,942
Ensembl chr12:4,474,958...4,498,910 		JBrowse link
G DCN decorin ISO RGD PMID:15713786 RGD:2311414 NCBI chr11:86,552,392...86,590,229
Ensembl chr11:86,551,072...86,586,891 		JBrowse link
G DEFB1 defensin beta 1 ISO RGD PMID:16740310 RGD:2312491 NCBI chr 8:6,643,753...6,652,209
Ensembl chr 8:6,643,556...6,651,699 		JBrowse link
G DHODH dihydroorotate dehydrogenase (quinone) ISO protein:decreased activity:mammary gland (rat) RGD PMID:1476792 PMID:1723607 RGD:11040445 RGD:5132591 NCBI chr 5:55,161,788...55,177,383
Ensembl chr 5:55,161,916...55,180,896 		JBrowse link
G DPP4 dipeptidyl peptidase 4 ISO RGD PMID:19765579 RGD:2313699 NCBI chr10:47,396,605...47,481,478
Ensembl chr10:47,394,093...47,480,893 		JBrowse link
G DRD1 dopamine receptor D1 treatment ISO protein:decreased activity:striatum (rat) RGD PMID:1386820 PMID:20513244 RGD:2311600 RGD:7248621 NCBI chr23:77,587,340...77,591,434 JBrowse link
G DRD2 dopamine receptor D2 ISO protein:altered activity:hypothalamus, pancreatic islet, brainstem (rat) RGD PMID:17174299 RGD:1624999 NCBI chr 1:104,774,632...104,843,417
Ensembl chr 1:104,774,180...104,842,736 		JBrowse link
G DUSP1 dual specificity phosphatase 1 ISO mRNA, protein:decreased expression:ventricle myocardium
mRNA:increased expression:retina		 RGD PMID:17063547 PMID:17647144 RGD:2298672 RGD:7771540 NCBI chr23:74,931,421...74,934,510
Ensembl chr23:74,929,863...74,934,532 		JBrowse link
G ECE1 endothelin converting enzyme 1 ISO mRNA:increased expression:thoracic aorta RGD PMID:23600389 RGD:7243858 NCBI chr20:111,212,567...111,342,755
Ensembl chr20:111,212,594...111,342,821 		JBrowse link
G EDN1 endothelin 1 treatment ISO mRNA:increased expression:heart, kidney, retina (rat)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:12458661 PMID:12967931 PMID:18351623 PMID:18516100 RGD:2312288 RGD:2313282 NCBI chr17:59,854,186...59,861,319
Ensembl chr17:59,853,699...59,861,198 		JBrowse link
G EDNRA endothelin receptor type A ISO RGD PMID:20690982 RGD:4892336 NCBI chr 7:93,980,983...94,043,863
Ensembl chr 7:93,985,797...94,042,296 		JBrowse link
G EEF2 eukaryotic translation elongation factor 2 treatment ISO protein:decreased expression:cardiac muscle: RGD PMID:7513958 RGD:10401649 NCBI chr 6:3,733,056...3,742,526
Ensembl chr 6:3,732,425...3,742,826 		JBrowse link
G EGFR epidermal growth factor receptor ISO protein:decreased tyrosine phosphorylation:cornea RGD PMID:21330660 RGD:5131482 NCBI chr21:3,664,622...3,853,492
Ensembl chr21:3,666,339...3,853,239 		JBrowse link
G ELN elastin ISO mRNA:increased expression:bladder: RGD PMID:18279932 RGD:9585725 NCBI chr28:8,999,164...9,048,703 JBrowse link
G ENO2 enolase 2 ISO protein:increased expression:brain RGD PMID:15780189 RGD:2293753 NCBI chr11:6,945,243...6,954,959
Ensembl chr11:6,945,413...6,957,304 		JBrowse link
G ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 ISO protein:decreased expression:retina: RGD PMID:22864860 RGD:9685437 NCBI chr 8:114,113,780...114,232,656
Ensembl chr 8:114,113,778...114,195,956 		JBrowse link
G ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 ISO protein,mRNA:increased expression:glial cell, retina:
protein:enzyme activity:platelet		 RGD PMID:17119848 PMID:18687327 RGD:9685473 RGD:9685486 NCBI chr 9:88,921,826...89,034,418
Ensembl chr 9:88,922,007...89,032,880 		JBrowse link
G EP300 E1A binding protein p300 treatment ISO mRNA:increased expression:heart (rat) RGD PMID:18351623 PMID:18413674 PMID:18657544 PMID:22228707 RGD:2312263 RGD:2312287 RGD:2312288 RGD:7296926 NCBI chr19:23,634,132...23,726,095
Ensembl chr19:23,634,571...23,724,979 		JBrowse link
G EPO erythropoietin ISO mRNA:increased expression:Schwann cell: RGD PMID:24673486 RGD:11041670 NCBI chr28:12,487,222...12,491,986
Ensembl chr28:12,489,766...12,491,908 		JBrowse link
G EPOR erythropoietin receptor ISO mRNA:increased expression:Schwann cell: RGD PMID:24673486 RGD:11041670 NCBI chr 6:10,313,382...10,320,196
Ensembl chr 6:10,313,775...10,320,066 		JBrowse link
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit treatment ISO RGD PMID:22228707 RGD:7296926 NCBI chr 6:38,857,067...38,900,177
Ensembl chr 6:38,854,803...38,872,967 		JBrowse link
G ERCC4 ERCC excision repair 4, endonuclease catalytic subunit treatment ISO RGD PMID:22228707 RGD:7296926 NCBI chr 5:13,378,282...13,410,307
Ensembl chr 5:13,378,401...13,406,541 		JBrowse link
G ESR1 estrogen receptor 1 ISO protein:decreased expression:vagina,nucleus
protein:decreased expression:penis		 RGD PMID:15596216 PMID:16734901 RGD:2306775 RGD:2314014 NCBI chr13:79,153,418...79,554,552
Ensembl chr13:79,270,265...79,554,549 		JBrowse link
G ESRRA estrogen related receptor alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:23090186 NCBI chr 1:9,918,741...9,929,481
Ensembl chr 1:9,917,436...9,929,450 		JBrowse link
G ETS1 ETS proto-oncogene 1, transcription factor ISO protein:increased expression:retina RGD PMID:17622743 RGD:2313849 NCBI chr 1:119,588,476...119,736,623
Ensembl chr 1:119,588,448...119,652,299 		JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit ISO protein:increased expression:kidney RGD PMID:23508046 RGD:9587808 NCBI chr21:117,380,518...117,515,224
Ensembl chr21:117,380,361...117,421,573 		JBrowse link
G F11R F11 receptor ISO RGD PMID:18506084 RGD:7488940 NCBI chr20:2,966,019...2,986,177
Ensembl chr20:2,966,164...2,984,269 		JBrowse link
G F3 coagulation factor III, tissue factor ISO protein:increased activity:kidney RGD PMID:15990447 RGD:2313862 NCBI chr20:38,726,690...38,738,457
Ensembl chr20:38,726,798...38,739,408 		JBrowse link
G F7 coagulation factor VII ISO protein:decreased activity:plasma (rat) RGD PMID:11474472 PMID:16779662 RGD:2312313 RGD:2312396 NCBI chr 3:91,109,864...91,122,707
Ensembl chr 3:91,110,380...91,123,327 		JBrowse link
G FABP3 fatty acid binding protein 3 ISO mRNA, protein:decreased expression:aorta RGD PMID:7744030 RGD:2307330 NCBI chr20:101,464,899...101,472,223
Ensembl chr20:101,464,960...101,474,350 		JBrowse link
G FABP4 fatty acid binding protein 4 ISO protein:decreased expresssion:fat cell RGD PMID:9059981 RGD:1625411 NCBI chr 8:76,895,516...76,900,153
Ensembl chr 8:76,894,512...76,900,212 		JBrowse link
G FADS1 fatty acid desaturase 1 ISO mRNA:decreased expression:liver RGD PMID:16099631 RGD:1625413 NCBI chr 1:12,037,173...12,051,907
Ensembl chr 1:12,037,513...12,055,159 		JBrowse link
G FASLG Fas ligand ISO protein:increased expression:heart ventricle RGD PMID:19820199 RGD:2314021 NCBI chr25:56,488,572...56,496,469
Ensembl chr25:56,489,417...56,496,251 		JBrowse link
G FBN1 fibrillin 1 ISO protein:increased expression:renal glomerulus (rat) RGD PMID:16380460 RGD:7365080 NCBI chr26:34,637,916...34,877,499
Ensembl chr26:34,638,838...34,879,217 		JBrowse link
G FGA fibrinogen alpha chain ISO protein:increased expression:plasma (rat) RGD PMID:23086277 RGD:9684989 NCBI chr 7:101,127,554...101,134,881
Ensembl chr 7:101,125,791...101,134,405 		JBrowse link
G FGF2 fibroblast growth factor 2 ISO protein:increased expression:vitreous humor RGD PMID:10792180 PMID:12663474 RGD:2315880 RGD:8655613 NCBI chr 7:70,089,394...70,157,423 JBrowse link
G FGF21 fibroblast growth factor 21 treatment ISO protein:decreased expression:serum:
CTD Direct Evidence: therapeutic		 RGD
CTD		 PMID:23262585 PMID:23499715 PMID:25359298 RGD:10401916 RGD:10401921 NCBI chr 6:42,006,125...42,008,749
Ensembl chr 6:42,006,064...42,008,736 		JBrowse link
G FLT1 fms related receptor tyrosine kinase 1 ISO mRNA:decreased expression:skeletal muscle
mRNA:decreased expression:heart		 RGD PMID:16741021 PMID:16816123 RGD:2313724 RGD:2313725 NCBI chr 3:7,412,506...7,608,122
Ensembl chr 3:7,412,172...7,607,967 		JBrowse link
G FN1 fibronectin 1 treatment ISO protein:increased expression:kidney RGD PMID:22228707 PMID:22937115 RGD:7206838 RGD:7296926 NCBI chr10:101,177,867...101,254,613
Ensembl chr10:101,176,789...101,254,633 		JBrowse link
G FOXA2 forkhead box A2 ISO mRNA:increased expression:kidney cortex RGD PMID:19433262 RGD:2312358 NCBI chr 2:51,577,127...51,585,168
Ensembl chr 2:51,577,833...51,580,297 		JBrowse link
G FOXA3 forkhead box A3 ISO mRNA:increased expression:liver RGD PMID:11018767 RGD:2315085 NCBI chr 6:39,309,439...39,320,102
Ensembl chr 6:39,310,108...39,320,095 		JBrowse link
G FOXO3 forkhead box O3 ISO CTD Direct Evidence: marker/mechanism
mRNA:decreased expression:liver:
protein:increased phosphorylation, increased expression:glomerulus, cytoplasm:		 CTD
RGD		 PMID:12683947 PMID:17082237 PMID:23090186 PMID:23792339 RGD:10402196 RGD:10402199 NCBI chr13:65,175,764...65,303,107
Ensembl chr13:65,195,376...65,301,725 		JBrowse link
G FOXP3 forkhead box P3 treatment ISO mRNA,protein:increased expression: peripheral blood, spleen, lymphoid node RGD PMID:18328191 PMID:32341701 RGD:38599142 RGD:38599143 NCBI chr  X:46,349,890...46,365,133 JBrowse link
G FURIN furin, paired basic amino acid cleaving enzyme disease_progression ISO protein:decreased expression:kidney RGD PMID:16541018 RGD:1582625 NCBI chr29:8,980,367...8,992,257
Ensembl chr29:8,979,720...8,988,235 		JBrowse link
G G6PC1 glucose-6-phosphatase catalytic subunit 1 treatment ISO protein:increased activity:liver, kidney RGD PMID:16176150 PMID:27366200 RGD:14695533 RGD:2315960 NCBI chr16:63,380,921...63,392,122
Ensembl chr16:63,381,382...63,391,540 		JBrowse link
G G6PD glucose-6-phosphate dehydrogenase treatment ISO protein:increased expression:lens
protein:decreased expression:liver		 RGD PMID:16718375 PMID:19374864 PMID:25116122 RGD:10449121 RGD:2307337 RGD:2307345 NCBI chr  X:128,768,028...128,788,366
Ensembl chr  X:128,770,268...128,786,961 		JBrowse link
G GABBR1 gamma-aminobutyric acid type B receptor subunit 1 ISO RGD PMID:2849069 RGD:2315971 NCBI chr17:42,985,816...43,017,278
Ensembl chr17:42,986,513...43,014,577 		JBrowse link
G GAL galanin and GMAP prepropeptide ISO protein:decreased expression:pancreatic islet RGD PMID:7505518 PMID:11489087 RGD:2313740 RGD:2313742 NCBI chr 1:5,849,947...5,857,355
Ensembl chr 1:5,849,952...5,857,072 		JBrowse link
G GALP galanin like peptide ISO mRNA:increased expression:arcuate nucleus, pars posterior RGD PMID:15256810 PMID:16046316 RGD:2313737 RGD:2313739 NCBI chr 6:48,762,469...48,775,642
Ensembl chr 6:48,764,036...48,775,136 		JBrowse link
G GAPDH glyceraldehyde-3-phosphate dehydrogenase treatment ISO RGD PMID:27655796 RGD:13792671 NCBI chr11:6,569,029...6,572,877 JBrowse link
G GATA4 GATA binding protein 4 ISO protein:increased serine phosphorylation:heart RGD PMID:22293779 RGD:7207042 NCBI chr 8:7,348,145...7,432,574
Ensembl chr 8:7,349,660...7,400,562 		JBrowse link
G GC GC vitamin D binding protein ISO protein:decreased expression:serum RGD PMID:3838933 RGD:2315540 NCBI chr 7:20,254,604...20,298,384
Ensembl chr 7:20,253,879...20,298,265 		JBrowse link
G GCG glucagon treatment ISO RGD PMID:18996945 RGD:10402370 NCBI chr10:47,550,097...47,560,610 JBrowse link
G GCH1 GTP cyclohydrolase 1 treatment ISO protein:increased degradation:heart
associated with type 1 diabetes mellitus		 RGD PMID:18061195 PMID:18596126 PMID:27295516 RGD:2314434 RGD:329961323 RGD:401700392 NCBI chr24:32,029,997...32,079,656
Ensembl chr24:32,027,648...32,079,490 		JBrowse link
G GCK glucokinase ISO protein:decreased activity:liver:reduced activity, energy of activation and affinity for glucose in streptozotocin diabetic rats
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:2132180 PMID:16123366 RGD:2301955 NCBI chr21:14,475,723...14,523,086
Ensembl chr21:14,507,902...14,523,850 		JBrowse link
G GCNT1 glucosaminyl (N-acetyl) transferase 1 ISO mRNA:increased expression:heart RGD PMID:7560067 RGD:632804 NCBI chr12:87,502,202...87,506,171
Ensembl chr12:87,503,999...87,505,285 		JBrowse link
G GFPT1 glutamine--fructose-6-phosphate transaminase 1 ISO protein:decreased expression:epididymal fat pad, liver, skeletal muscle RGD PMID:7589852 RGD:2313355 NCBI chr14:37,740,332...37,803,389
Ensembl chr14:37,740,358...37,802,143 		JBrowse link
G GHR growth hormone receptor ISO RGD PMID:7964296 PMID:12529387 RGD:11567222 RGD:2307365 NCBI chr 4:41,171,038...41,464,474
Ensembl chr 4:41,285,712...41,464,666 		JBrowse link
G GHRH growth hormone releasing hormone treatment ISO RGD PMID:22393012 RGD:10401241 NCBI chr 2:26,482,734...26,493,761
Ensembl chr 2:26,487,973...26,493,499 		JBrowse link
G GHRHR growth hormone releasing hormone receptor ISO RGD PMID:18285528 RGD:10401258 NCBI chr21:27,402,765...27,417,536
Ensembl chr21:27,404,886...27,417,521 		JBrowse link
G GHRL ghrelin and obestatin prepropeptide disease_progression ISO protein:increased expression:plasma RGD PMID:18657539 PMID:23965296 RGD:12905048 RGD:2313750 NCBI chr22:46,326,458...46,332,906
Ensembl chr22:46,325,913...46,330,962 		JBrowse link
G GHSR growth hormone secretagogue receptor ISO mRNA:increased expression:Arcuate nucleus : RGD PMID:23965296 RGD:12905048 NCBI chr15:17,008,185...17,013,504
Ensembl chr15:17,009,369...17,012,618 		JBrowse link
G GIP gastric inhibitory polypeptide ISO mRNA:increased expression:retina (rat) RGD PMID:12789546 RGD:2312548 NCBI chr16:69,367,030...69,377,563
Ensembl chr16:69,367,207...69,377,155 		JBrowse link
G GIPR gastric inhibitory polypeptide receptor ISO mRNA:increased expression:retina (rat) RGD PMID:12789546 RGD:2312548 NCBI chr 6:39,108,319...39,122,973
Ensembl chr 6:39,110,387...39,122,874 		JBrowse link
G GJA1 gap junction protein alpha 1 treatment ISO protein:altered expression:retina:
protein:decreased expression:retina, blood vessel
protein:increased expression:dermis		 RGD PMID:20130277 PMID:20609064 PMID:22110070 PMID:22455314 RGD:7207269 RGD:7207415 RGD:7364887 RGD:8662383 NCBI chr13:52,397,291...52,410,341
Ensembl chr13:52,396,109...52,410,339 		JBrowse link
G GJA5 gap junction protein alpha 5 treatment ISO RGD PMID:20609064 RGD:7207415
G GJB2 gap junction protein beta 2 ISO mRNA,protein:decreased expression:retina: RGD PMID:22110070 RGD:7364887 NCBI chr 3:801,786...808,165
Ensembl chr 3:807,379...808,059 		JBrowse link
G GJB6 gap junction protein beta 6 ISO RGD PMID:21567444 RGD:7364783 NCBI chr 3:775,410...783,770
Ensembl chr 3:782,251...783,036 		JBrowse link
G GJD3 gap junction protein delta 3 ISO protein:decreased expression:retina: RGD PMID:23385797 RGD:7364769 NCBI chr16:65,811,111...65,815,128
Ensembl chr16:65,811,981...65,812,862 		JBrowse link
G GLP1R glucagon like peptide 1 receptor ISO RGD PMID:10580413 RGD:1624356 NCBI chr17:33,053,442...33,092,806
Ensembl chr17:33,054,574...33,091,422 		JBrowse link
G GLRX glutaredoxin ISO protein:increase activity:retina: RGD PMID:17324929 RGD:9686046 NCBI chr 4:89,687,354...89,696,236
Ensembl chr 4:89,685,984...89,696,231 		JBrowse link
G GLUL glutamate-ammonia ligase treatment ISO protein:decreased expression:retina
mRNA, protein:decreased expression: retina		 RGD PMID:21770802 PMID:23284834 PMID:23595285 PMID:25335981 PMID:26677078 RGD:401794412 RGD:401794418 RGD:401794421 RGD:401794423 RGD:401794586 NCBI chr25:46,988,853...46,998,112
Ensembl chr25:46,989,205...47,000,555 		JBrowse link
G GMPS guanine monophosphate synthase ISO protein:increased activity:liver (rat) RGD PMID:3043317 RGD:5135485 NCBI chr15:34,817,603...34,885,363
Ensembl chr15:34,815,066...34,885,228 		JBrowse link
G GNAT1 G protein subunit alpha transducin 1 ISO protein:decreased expression:retina RGD PMID:15939031 RGD:1600001 NCBI chr22:11,577,192...11,582,789
Ensembl chr22:11,577,997...11,581,223 		JBrowse link
G GNAT3 G protein subunit alpha transducin 3 ISO mRNA, protein;increased expression:taste bud RGD PMID:18824257 RGD:2302147 NCBI chr21:68,372,715...68,431,972
Ensembl chr21:68,374,992...68,431,485 		JBrowse link
G GPAM glycerol-3-phosphate acyltransferase, mitochondrial ISO CTD Direct Evidence: marker/mechanism CTD PMID:9452481 NCBI chr 9:105,049,954...105,083,750
Ensembl chr 9:105,049,711...105,113,374 		JBrowse link
G GPD2 glycerol-3-phosphate dehydrogenase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16123366 NCBI chr10:41,832,772...41,984,109
Ensembl chr10:41,834,013...41,986,423 		JBrowse link
G GPX1 glutathione peroxidase 1 treatment ISO protein:increased expression:liver
CTD Direct Evidence: marker/mechanism
protein:increased expression:glomerulus		 RGD
CTD		 PMID:15039483 PMID:16123366 PMID:18387670 PMID:19229592 PMID:25744399 RGD:11353782 RGD:2306161 RGD:2306606 RGD:2306607 NCBI chr22:10,754,976...10,756,617 JBrowse link
G GPX3 glutathione peroxidase 3 treatment ISO RGD PMID:12753302 PMID:16651743 PMID:23407453 PMID:32546886 RGD:2312629 RGD:2312631 RGD:401827857 RGD:401827917 NCBI chr23:53,576,950...53,585,321 JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 treatment ISO RGD PMID:23595285 RGD:401794586 NCBI chr12:1,020,556...1,050,568
Ensembl chr12:1,019,263...1,050,231 		JBrowse link
G GRIN2B glutamate ionotropic receptor NMDA type subunit 2B ISO mRNA, protein:increased expression:cerebellum (rat) RGD PMID:20056114 RGD:4107025 NCBI chr11:13,444,155...13,873,034
Ensembl chr11:13,456,968...13,873,202 		JBrowse link
G GRK1 G protein-coupled receptor kinase 1 ISO protein:increased expression:retina RGD PMID:15939031 RGD:1600001 NCBI chr 3:91,633,902...91,655,989
Ensembl chr 3:91,636,813...91,653,521 		JBrowse link
G GSK3A glycogen synthase kinase 3 alpha treatment ISO RGD PMID:8526919 RGD:10401824 NCBI chr 6:36,434,966...36,447,676
Ensembl chr 6:36,435,578...36,447,633 		JBrowse link
G GSR glutathione-disulfide reductase treatment ISO CTD Direct Evidence: marker/mechanism
protein:decreased activity:plasma:		 RGD
CTD		 PMID:20187988 PMID:20620209 PMID:25050809 RGD:10401889 RGD:7257587 NCBI chr 8:28,778,713...28,851,907 JBrowse link
G GSTA4 glutathione S-transferase alpha 4 ISO protein:increased expression:pancreas, kidney, liver (rat) RGD PMID:14693714 RGD:5687773 NCBI chr17:19,575,835...19,591,713
Ensembl chr17:19,575,876...19,591,919 		JBrowse link
G GUK1 guanylate kinase 1 ISO protein:decreased expression:retina (rat) RGD PMID:17465459 RGD:5147874 NCBI chr25:1,579,382...1,587,623
Ensembl chr25:1,579,610...1,587,419 		JBrowse link
G H6PD hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase ISO RGD PMID:20923496 RGD:6784507 NCBI chr20:122,502,084...122,531,214
Ensembl chr20:122,503,687...122,526,074 		JBrowse link
G HADH hydroxyacyl-CoA dehydrogenase ISO RGD PMID:7050060 RGD:2302232 NCBI chr 7:55,919,499...55,965,074
Ensembl chr 7:55,919,623...55,964,857 		JBrowse link
G HADHA hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha ISO protein:decreased expression:brain RGD PMID:25260493 RGD:10047114 NCBI chr14:81,411,620...81,468,415
Ensembl chr14:81,411,648...81,472,257 		JBrowse link
G HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 ISO protein:increased expression:neuron: RGD PMID:19815055 RGD:9693680 NCBI chr 4:44,029,173...44,443,669 JBrowse link
G HCN2 hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 ISO protein:increased expression:neuron: RGD PMID:19815055 RGD:9693680 NCBI chr 6:326,437...358,119
Ensembl chr 6:324,517...358,119 		JBrowse link
G HCN3 hyperpolarization activated cyclic nucleotide gated potassium channel 3 ISO protein:increased expression:neuron: RGD PMID:19815055 RGD:9693680 NCBI chr20:8,546,609...8,558,911
Ensembl chr20:8,545,720...8,558,056 		JBrowse link
G HDAC1 histone deacetylase 1 ISO protein:increased activity:renal cortex: RGD PMID:19553350 RGD:9590229 NCBI chr20:100,529,782...100,575,953
Ensembl chr20:100,530,369...100,558,556 		JBrowse link
G HDAC2 histone deacetylase 2 ISO protein:increased activity:renal cortex: RGD PMID:19553350 RGD:9590229 NCBI chr13:59,873,248...59,904,542
Ensembl chr13:59,873,767...59,905,742 		JBrowse link
G HDAC4 histone deacetylase 4 ISO protein:increased activity:renal cortex: RGD PMID:19553350 RGD:9590229 NCBI chr10:125,098,375...125,450,524
Ensembl chr10:125,098,366...125,403,227 		JBrowse link
G HGF hepatocyte growth factor ISO protein:increased expression:kidney RGD PMID:16297324 RGD:2313568 NCBI chr21:67,118,785...67,193,506
Ensembl chr21:67,120,722...67,193,504 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha ISO protein:increased expression:sciatic nerve (rat) RGD PMID:15663958 RGD:8694461 NCBI chr24:38,873,830...38,927,657
Ensembl chr24:38,873,861...38,928,288 		JBrowse link
G HK1 hexokinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16123366 NCBI chr 9:61,917,501...62,029,737
Ensembl chr 9:61,917,440...62,001,843 		JBrowse link
G HMBS hydroxymethylbilane synthase ISO protein:decreased activity:liver (rat) RGD PMID:6688350 RGD:4144808 NCBI chr 1:110,457,799...110,466,361
Ensembl chr 1:110,457,537...110,466,095 		JBrowse link
G HMGB1 high mobility group box 1 ISO protein:increased expression, altered localization:retina, cytoplasm
associated with Endotoxemia;protein:increased expression:serum		 RGD PMID:19959191 PMID:23261684 RGD:10402069 RGD:2316737 NCBI chr 3:9,353,333...9,357,765 JBrowse link
G HMGCL 3-hydroxy-3-methylglutaryl-CoA lyase ISO protein:increased activity:liver (rat) RGD PMID:5667251 RGD:2326171 NCBI chr20:108,846,313...108,883,702
Ensembl chr20:108,860,613...108,884,473 		JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase ISO RGD PMID:15111316 RGD:2313760 NCBI chr 4:69,664,784...69,690,343
Ensembl chr 4:69,665,417...69,688,686 		JBrowse link
G HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 ISO protein:increased expression:pancreas RGD PMID:18452227 RGD:2302233 NCBI chr 4:42,083,523...42,107,410
Ensembl chr 4:42,080,949...42,107,409 		JBrowse link
G HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 ISO protein:increased expression:liver (rat) RGD PMID:7902069 RGD:2326135 NCBI chr20:14,018,669...14,040,934
Ensembl chr20:14,019,692...14,041,016 		JBrowse link
G HMOX1 heme oxygenase 1 ISO CTD Direct Evidence: marker/mechanism|therapeutic RGD
CTD		 PMID:15734859 PMID:16123366 PMID:16959961 PMID:18375438 PMID:19804535 RGD:1582713 NCBI chr19:18,144,466...18,157,944
Ensembl chr19:18,144,545...18,157,971 		JBrowse link
G HNF4A hepatocyte nuclear factor 4 alpha ISO mRNA:decreased expression:kidney, liver
protein:increased expression:liver:		 RGD PMID:18184923 PMID:19179483 RGD:12904769 RGD:2301838 NCBI chr 2:19,390,870...19,466,300
Ensembl chr 2:19,388,891...19,421,664 		JBrowse link
G HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 ISO protein:increased expression:urinary bladder (rat) RGD PMID:18337374 RGD:9685410 NCBI chr21:32,167,126...32,178,031
Ensembl chr21:32,167,337...32,176,980 		JBrowse link
G HNRNPK heterogeneous nuclear ribonucleoprotein K treatment ISO RGD PMID:16837467 RGD:10002795 NCBI chr12:94,768,403...94,789,957
Ensembl chr12:94,768,480...94,789,743 		JBrowse link
G HPRT1 hypoxanthine phosphoribosyltransferase 1 ISO protein:decreased activity:liver (rat) RGD PMID:3043317 RGD:5135485 NCBI chr  X:109,629,674...109,671,409 JBrowse link
G HRAS HRas proto-oncogene, GTPase ISO mRNA, protein:increased expression:retina blood vessel RGD PMID:18514235 RGD:2314841 NCBI chr 1:343,613...345,782
Ensembl chr 1:343,506...346,637 		JBrowse link
G HSD11B1 hydroxysteroid 11-beta dehydrogenase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14697232 NCBI chr25:19,720,096...19,772,806
Ensembl chr25:19,719,848...19,750,200 		JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 ISO mRNA:decreased expression:brain (rat) RGD PMID:21104931 RGD:5686396 NCBI chr24:80,016,352...80,019,130
Ensembl chr24:80,016,232...80,019,120 		JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 ISO RGD PMID:17280490 RGD:1624229 NCBI chr10:83,003,266...83,017,397
Ensembl chr10:83,003,717...83,017,363 		JBrowse link
G HSPG2 heparan sulfate proteoglycan 2 ISO mRNA:decreased expression:retina RGD PMID:9068943 RGD:1624265 NCBI chr20:110,693,858...110,809,467
Ensembl chr20:110,693,854...110,809,466 		JBrowse link
G HTR2A 5-hydroxytryptamine receptor 2A ISO protein:increased expression:lung RGD PMID:21521772 RGD:5135278 NCBI chr 3:24,820,029...24,884,472
Ensembl chr 3:24,820,035...24,883,432 		JBrowse link
G IAPP islet amyloid polypeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:16123366 NCBI chr11:21,240,947...21,247,409
Ensembl chr11:21,241,514...21,247,207 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 treatment ISO mRNA:increased expression:aorta
protein:increased expression:serum
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:14871415 PMID:18093596 PMID:18413153 PMID:20136425 PMID:20388520 More... RGD:2306987 RGD:2306988 RGD:8547703 NCBI chr 6:9,320,991...9,338,125
Ensembl chr 6:9,322,550...9,338,263 		JBrowse link
G IDE insulin degrading enzyme ISO protein:decreased expression:cerebral cortex RGD PMID:29940507 RGD:13792791 NCBI chr 9:85,722,728...85,843,247
Ensembl chr 9:85,721,886...85,843,117 		JBrowse link
G IFNAR1 interferon alpha and beta receptor subunit 1 ISO RGD PMID:27999109 RGD:12910492 NCBI chr 2:58,824,600...58,854,519
Ensembl chr 2:58,825,916...58,854,568 		JBrowse link
G IFNG interferon gamma ISO mRNA:increased expression:pancreas
CTD Direct Evidence: marker/mechanism
protein:increased expression:retina		 RGD
CTD		 PMID:18789669 PMID:20213480 PMID:21340626 RGD:2311492 RGD:5147915 NCBI chr11:63,785,493...63,791,071
Ensembl chr11:63,786,041...63,790,473 		JBrowse link
G IGF1 insulin like growth factor 1 ISO CTD Direct Evidence: therapeutic
protein:decreased expression:heart
protein:decreased expression:cerebellum, serum
protein:decreased expression:oviduct
mRNA,protein:decreased expression:corpus cavernosum:
mRNA:altered expression:kidney		 CTD
RGD		 PMID:7536658 PMID:18676006 PMID:19382144 PMID:20555424 PMID:22133301 More... RGD:10046054 RGD:152176653 RGD:2306671 RGD:2311502 RGD:4142788 NCBI chr11:97,624,498...97,708,730
Ensembl chr11:97,631,189...97,707,308 		JBrowse link
G IGF1R insulin like growth factor 1 receptor ISO protein:decreased phosphorylation:heart
protein:decreased expression:oviduct		 RGD PMID:18676006 PMID:20555424 RGD:2311502 RGD:4142788 NCBI chr29:17,212,206...17,534,036
Ensembl chr29:17,459,404...17,526,930 		JBrowse link
G IGF2 insulin like growth factor 2 treatment ISO mRNA:decreased expression:brain
protein:increased expression:oviduct
protein:increased expression:multiple
DNA, mRNA:hypermethylation, decreased expression		 RGD PMID:10686593 PMID:17184497 PMID:18676006 PMID:18724775 PMID:23364485 RGD:10402565 RGD:2311502 RGD:2311511 RGD:2311513 RGD:5509973 NCBI chr 1:1,937,414...1,951,238
Ensembl chr 1:1,936,830...1,945,388 		JBrowse link
G IGF2R insulin like growth factor 2 receptor ISO protein:increased expression:oviduct RGD PMID:18676006 RGD:2311502 NCBI chr13:87,587,717...87,723,795
Ensembl chr13:87,587,907...87,724,116 		JBrowse link
G IGFBP1 insulin like growth factor binding protein 1 ISO mRNA:altered expression:kidney RGD PMID:7536658 RGD:152176653 NCBI chr21:12,932,727...12,939,078
Ensembl chr21:12,932,732...12,937,891 		JBrowse link
G IGFBP2 insulin like growth factor binding protein 2 ISO mRNA:altered expression:kidney RGD PMID:7536658 RGD:152176653 NCBI chr10:102,469,611...102,503,229
Ensembl chr10:102,469,669...102,503,276 		JBrowse link
G IGFBP3 insulin like growth factor binding protein 3 treatment ISO mRNA, protein:increased expression:penis
protein:increased expression:skeletal muscle
mRNA:altered expression:kidney		 RGD PMID:7536658 PMID:16180585 PMID:18068478 PMID:25582342 RGD:12743617 RGD:152176653 RGD:2289159 RGD:2313766 NCBI chr21:12,905,309...12,914,199
Ensembl chr21:12,905,280...12,914,205 		JBrowse link
G IGFBP4 insulin like growth factor binding protein 4 ISO mRNA:altered expression:kidney RGD PMID:7536658 RGD:152176653 NCBI chr16:65,722,216...65,737,380
Ensembl chr16:65,723,361...65,737,072 		JBrowse link
G IGFBP5 insulin like growth factor binding protein 5 ISO mRNA:altered expression:kidney RGD PMID:7536658 RGD:152176653 NCBI chr10:102,510,939...102,531,710
Ensembl chr10:102,510,897...102,531,724 		JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta ISO protein:increased phosphorylation:liver RGD PMID:20362663 RGD:7495777 NCBI chr 8:40,267,532...40,325,282
Ensembl chr 8:40,268,079...40,326,381 		JBrowse link
G IL10 interleukin 10 ISO protein:increase expression:serum RGD PMID:18779928 PMID:18787467 RGD:2308945 RGD:2308946 NCBI chr25:22,590,389...22,595,877
Ensembl chr25:22,590,962...22,594,836 		JBrowse link
G IL17A interleukin 17A ISO protein:increased expression:gingiva (rat) RGD PMID:21826658 RGD:9068940 NCBI chr17:20,314,082...20,319,917
Ensembl chr17:20,315,773...20,318,785 		JBrowse link
G IL1A interleukin 1 alpha ISO protein:increased expression:heart RGD PMID:20555424 RGD:4142788 NCBI chr14:15,789,710...15,801,938
Ensembl chr14:15,789,013...15,796,611 		JBrowse link
G IL1B interleukin 1 beta ISO mRNA:increased expression:skeletal muscle
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:12123627 PMID:17669395 PMID:23197974 RGD:1626620 RGD:7175529 NCBI chr14:15,844,628...15,852,652
Ensembl chr14:15,844,672...15,850,729 		JBrowse link
G IL1RN interleukin 1 receptor antagonist ISO human gene in a rat model RGD PMID:8037760 PMID:17221214 PMID:19545727 RGD:6907397 RGD:6907425 RGD:8551855 NCBI chr14:16,136,667...16,152,451
Ensembl chr14:16,146,333...16,151,326 		JBrowse link
G IL2 interleukin 2 ISO protein:increased expression:retina RGD PMID:20213480 RGD:5147915 NCBI chr 7:69,729,635...69,736,279
Ensembl chr 7:69,730,282...69,734,969 		JBrowse link
G IL2RA interleukin 2 receptor subunit alpha ISO RGD PMID:18503494 RGD:2311530 NCBI chr 9:6,134,961...6,187,731
Ensembl chr 9:6,141,430...6,149,447 		JBrowse link
G IL4 interleukin 4 treatment ISO RGD PMID:25191525 RGD:10402795 NCBI chr23:35,492,158...35,501,349
Ensembl chr23:35,492,939...35,501,258 		JBrowse link
G IL4R interleukin 4 receptor ISO RGD PMID:12165974 RGD:4889983 NCBI chr 5:25,019,638...25,069,732
Ensembl chr 5:25,046,701...25,070,015 		JBrowse link
G IL6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:extracellular space (rat)
protein:increased expression:heart
protein:increased expression:blood		 CTD
RGD		 PMID:18976114 PMID:19328014 PMID:20555424 PMID:22138235 PMID:24582317 RGD:11049554 RGD:2306984 RGD:2307252 RGD:4142788 NCBI chr21:35,577,513...35,582,385
Ensembl chr21:35,577,939...35,582,237 		JBrowse link
G INSIG1 insulin induced gene 1 ISO RGD PMID:16327801 RGD:2308858 NCBI chr21:123,448,614...123,460,778
Ensembl chr21:123,449,106...123,460,807 		JBrowse link
G INSR insulin receptor treatment
disease_progression		 ISO CTD Direct Evidence: marker/mechanism
mRNA, protein:increased expression:liver, adipose tissue (rat)
protein:decreased expression:kidney
protein:altered activity:liver plasma membrane
mRNA:increased expression:liver nuclei, liver cell membrane (rat)
protein:decreased expression:erythrocyte (rat)		 CTD
RGD		 PMID:1280238 PMID:2180315 PMID:9243097 PMID:17855644 PMID:18376071 More... RGD:10403045 RGD:14981592 RGD:15036814 RGD:2290475 RGD:2307025 RGD:2307339 NCBI chr 6:6,625,951...6,803,610
Ensembl chr 6:6,630,777...6,803,592 		JBrowse link
G IRS1 insulin receptor substrate 1 treatment ISO mRNA, protein:decreased expression:multiple
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:22138235 PMID:22820932 PMID:22983684 RGD:7207061 RGD:7207063 NCBI chr10:112,748,283...112,812,368 JBrowse link
G IRS2 insulin receptor substrate 2 ISO CTD Direct Evidence: marker/mechanism
protein:decreased phosphorylation:heart		 CTD
RGD		 PMID:20555424 PMID:25808216 RGD:4142788 NCBI chr 3:88,045,439...88,076,468 JBrowse link
G ISG15 ISG15 ubiquitin like modifier ISO RGD PMID:20973890 RGD:5490977 NCBI chr20:130,419,909...130,421,409
Ensembl chr20:130,419,782...130,421,380 		JBrowse link
G ITGA3 integrin subunit alpha 3 ISO protein:decreased expression:renal cortex (rat) RGD PMID:20525748 RGD:2325818 NCBI chr16:43,248,341...43,282,045
Ensembl chr16:43,250,435...43,281,670 		JBrowse link
G ITGAM integrin subunit alpha M ISO protein:increased expression:neutrophil (rat) RGD PMID:10752954 RGD:329902069 NCBI chr 5:27,957,162...28,042,697
Ensembl chr 5:27,957,324...28,042,691 		JBrowse link
G ITGB1 integrin subunit beta 1 ISO protein:decreased expression:epidermal stem cell (rat) RGD PMID:20187441 RGD:2325322 NCBI chr 9:32,201,030...32,258,247
Ensembl chr 9:32,202,204...32,258,154 		JBrowse link
G ITGB3 integrin subunit beta 3 ISO protein:increased expression:aorta: RGD PMID:12606526 RGD:8693385 NCBI chr16:59,372,171...59,431,434
Ensembl chr16:59,374,889...59,410,857 		JBrowse link
G JAK3 Janus kinase 3 ISO protein:increased expression:retina RGD PMID:21575160 RGD:11533943 NCBI chr 6:16,301,760...16,323,343
Ensembl chr 6:16,300,525...16,322,859 		JBrowse link
G KCNA2 potassium voltage-gated channel subfamily A member 2 ISO RGD PMID:17982915 RGD:7242761 NCBI chr20:22,933,524...22,942,074
Ensembl chr20:22,940,154...22,941,650 		JBrowse link
G KCNA5 potassium voltage-gated channel subfamily A member 5 ISO RGD PMID:17982915 RGD:7242761 NCBI chr11:5,085,221...5,088,135
Ensembl chr11:5,085,518...5,087,335 		JBrowse link
G KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 ISO mRNA:decreased expression:left heart ventricle RGD PMID:19267230 RGD:7243942 NCBI chr 2:57,833,459...57,841,052
Ensembl chr 2:57,833,629...57,834,000 		JBrowse link
G KCNJ11 potassium inwardly rectifying channel subfamily J member 11 ISO protein:decreased expression:brain
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:16123366 PMID:23785408 RGD:7296920 NCBI chr 1:47,582,519...47,586,466
Ensembl chr 1:47,583,629...47,584,801 		JBrowse link
G KCNMA1 potassium calcium-activated channel subfamily M alpha 1 ISO mRNA, protein:decreased expression:aorta, smooth muscle RGD PMID:24589593 RGD:10412030 NCBI chr 9:53,727,790...54,557,252
Ensembl chr 9:54,182,910...54,554,716 		JBrowse link
G KCNMB1 potassium calcium-activated channel subfamily M regulatory beta subunit 1 ISO protein:decreased expression:aorta, smooth muscle RGD PMID:24589593 RGD:10412030 NCBI chr23:72,580,617...72,591,070
Ensembl chr23:72,577,813...72,591,588 		JBrowse link
G KCNN4 potassium calcium-activated channel subfamily N member 4 ameliorates ISO mRNA, protein:increased expression:aorta, smooth muscle RGD PMID:24589593 PMID:29167619 RGD:10412030 RGD:401784495 NCBI chr 6:37,289,088...37,316,850 JBrowse link
G KDM6A lysine demethylase 6A ISO RGD PMID:31266808 RGD:151665138 NCBI chr  X:42,053,272...42,291,013
Ensembl chr  X:42,053,336...42,290,526 		JBrowse link
G KDR kinase insert domain receptor ISO mRNA:increased expression:retina
mRNA:decreased expression:skeletal muscle
mRNA:decreased expression:heart		 RGD PMID:16741021 PMID:16816123 PMID:22121831 RGD:2313724 RGD:2313725 RGD:5684538 NCBI chr 7:13,435,059...13,482,236
Ensembl chr 7:13,435,096...13,482,771 		JBrowse link
G KHK ketohexokinase ISO RGD PMID:6088170 RGD:2302253 NCBI chr14:80,518,049...80,531,643
Ensembl chr14:80,514,825...80,531,653 		JBrowse link
G KIF1A kinesin family member 1A ISO mRNA:increased expression:hippocampus RGD PMID:23776493 RGD:11059542 NCBI chr10:126,784,843...126,890,649
Ensembl chr10:126,781,589...126,867,219 		JBrowse link
G KIF5B kinesin family member 5B ISO mRNA:increased expression:hippocampus RGD PMID:23776493 RGD:11059542 NCBI chr 9:31,321,615...31,369,549
Ensembl chr 9:31,320,549...31,369,519 		JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase ISO protein:increased expression:pancreas RGD PMID:17235568 RGD:2311225 NCBI chr 7:13,808,104...13,891,003
Ensembl chr 7:13,808,037...13,890,976 		JBrowse link
G KLK1 kallikrein 1 ISO mRNA:decreased expression:myocardium RGD PMID:10604522 RGD:1641812 NCBI chr 6:43,867,629...43,873,364
Ensembl chr 6:43,867,596...43,872,178 		JBrowse link
G KMT5C lysine methyltransferase 5C ISO mRNA:increased expression:retina RGD PMID:21357467 RGD:9586742 NCBI chr 6:47,942,100...47,950,364
Ensembl chr 6:47,944,197...47,949,693 		JBrowse link
G LCN2 lipocalin 2 ISO mRNA:increased expression:retina (rat)
protein:increased expression:urine		 RGD PMID:15623795 PMID:23085980 RGD:2316515 RGD:7245484 NCBI chr12:9,976,278...9,981,087
Ensembl chr12:9,976,614...9,980,870 		JBrowse link
G LCT lactase ISO RGD PMID:16021836 RGD:1600251 NCBI chr10:19,994,398...20,049,325
Ensembl chr10:19,994,384...20,049,097 		JBrowse link
G LDLR low density lipoprotein receptor ISO mRNA:decreased expression:liver RGD PMID:18054320 RGD:2324626 NCBI chr 6:10,062,204...10,091,780
Ensembl chr 6:10,062,790...10,091,377 		JBrowse link
G LEP leptin onset ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:19428774 PMID:19491210 PMID:20695765 PMID:28242381 PMID:31313498 More... RGD:2311124 RGD:2311126 RGD:5128579 NCBI chr21:97,056,913...97,071,161
Ensembl chr21:97,057,529...97,071,220 		JBrowse link
G LEPR leptin receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:15093691 PMID:16427799 PMID:17065336 PMID:19452630 PMID:19478208 More... NCBI chr20:67,454,205...67,567,524
Ensembl chr20:67,454,334...67,524,229 		JBrowse link
G LGALS3 galectin 3 treatment ISO RGD PMID:21249158 RGD:9685210 NCBI chr24:32,311,343...32,328,335
Ensembl chr24:32,311,271...32,328,339 		JBrowse link
G LIPC lipase C, hepatic type ISO protein:decreased activity:liver (rat) RGD PMID:1868959 PMID:18758746 RGD:2307432 RGD:2308849 NCBI chr26:24,946,843...25,109,338
Ensembl chr26:24,946,673...25,087,921 		JBrowse link
G LITAF lipopolysaccharide induced TNF factor ISO protein:increased expression:retina RGD PMID:21575160 RGD:11533943 NCBI chr 5:11,023,158...11,099,133
Ensembl chr 5:11,021,717...11,059,149 		JBrowse link
G LOC103214902 sodium/hydrogen exchanger 3 ISO CTD Direct Evidence: marker/mechanism
protein:increased activity:kidney cortex		 CTD
RGD		 PMID:16244498 PMID:20003708 RGD:1625673 NCBI chr 4:362,417...408,113
Ensembl chr 4:365,135...408,033 		JBrowse link
G LOC103223058 glutathione hydrolase light chain 2 ISO protein:increased activity:serum RGD PMID:18291430 RGD:2315577 NCBI chr19:7,353,922...7,406,392 JBrowse link
G LOC103225759 somatostatin receptor type 5 ISO RGD PMID:7956902 RGD:2325008 NCBI chr 5:967,785...976,353
Ensembl chr 5:973,791...974,885 		JBrowse link
G LOC103225962 alpha-L-fucosidase 1 ISO RGD PMID:3924473 RGD:2315947 NCBI chr20:108,823,047...108,832,926 JBrowse link
G LOC103226928 aldo-keto reductase family 1 member B1 ISO mRNA:increased expression:kidney (rat) RGD PMID:8204669 RGD:8548781 NCBI chr21:103,060,018...103,076,844
Ensembl chr21:103,059,991...103,077,341 		JBrowse link
G LOC103231892 metalloproteinase inhibitor 1 ISO protein:increased expression:kidney RGD PMID:17569353 RGD:2290354 NCBI chr  X:44,759,412...44,763,243
Ensembl chr  X:44,760,531...44,765,571 		JBrowse link
G LOC103233058 fractalkine ISO mRNA:increased expression:kidney
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:15153757 PMID:20388520 RGD:4891992 NCBI chr 5:43,310,711...43,323,533
Ensembl chr 5:43,310,753...43,323,529 		JBrowse link
G LOC103233451 cytochrome b-245 light chain ISO mRNA:increased expression:pancreas:
mRNA, protein:increased expression:aorta
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:11812764 PMID:12967931 PMID:20226688 PMID:23905384 RGD:11040693 RGD:2317852 NCBI chr 5:74,023,134...74,030,793
Ensembl chr 5:74,023,082...74,030,750 		JBrowse link
G LOC103239768 calcitonin ISO protein:increased expression:penis erectile tissue, seminal vesicle
protein:decreased expression:dorsal root ganglion, neuron		 RGD PMID:17151309 PMID:19152794 RGD:2314033 RGD:2314035 NCBI chr 1:49,946,574...49,956,010
Ensembl chr 1:49,951,694...49,954,092 		JBrowse link
G LOC103243413 signal transducer and activator of transcription 5B ISO RGD PMID:17003334 RGD:2291940 NCBI chr16:63,997,486...64,070,392
Ensembl chr16:63,997,441...64,070,445 		JBrowse link
G LOC103247994 DNA-binding protein inhibitor ID-1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16123366 NCBI chr 2:36,008,660...36,009,880
Ensembl chr 2:36,008,636...36,010,017 		JBrowse link
G LPIN1 lipin 1 ISO mRNA:increased expression:skeletal muscle RGD PMID:14718385 RGD:1641826 NCBI chr14:95,777,976...95,926,420
Ensembl chr14:95,780,478...95,926,419 		JBrowse link
G LPL lipoprotein lipase treatment ISO RGD PMID:18780778 PMID:27158912 RGD:13794379 RGD:2313303 NCBI chr 8:18,009,049...18,038,315
Ensembl chr 8:18,009,093...18,038,598 		JBrowse link
G LRP2 LDL receptor related protein 2 ISO protein:decreased expression:kidney, proximal convoluted tubule, apical plasma membrane RGD PMID:11685557 RGD:1641843 NCBI chr10:54,672,876...54,889,374
Ensembl chr10:54,711,517...54,889,208 		JBrowse link
G LTBP1 latent transforming growth factor beta binding protein 1 ISO RGD PMID:17574405 RGD:2302087 NCBI chr14:74,063,258...74,441,042
Ensembl chr14:74,064,087...74,548,825 		JBrowse link
G MAFA MAF bZIP transcription factor A treatment ISO RGD PMID:28487936 RGD:13506743 NCBI chr 8:137,647,459...137,650,169
Ensembl chr 8:137,648,746...137,649,804 		JBrowse link
G MAP2K3 mitogen-activated protein kinase kinase 3 ISO mRNA:increased expression:kidney, glomerulus RGD PMID:11473637 RGD:7495813 NCBI chr16:19,396,377...19,427,617
Ensembl chr16:19,396,452...19,427,652 		JBrowse link
G MAP2K6 mitogen-activated protein kinase kinase 6 ISO mRNA:increased expression:kidney, glomerulus RGD PMID:11473637 RGD:7495813 NCBI chr16:52,045,398...52,188,416
Ensembl chr16:52,057,784...52,187,997 		JBrowse link
G MAP3K5 mitogen-activated protein kinase kinase kinase 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18342293 NCBI chr13:36,614,489...36,858,524
Ensembl chr13:36,615,633...36,858,601 		JBrowse link
G MAP3K8 mitogen-activated protein kinase kinase kinase 8 ISO protein:increased activity:serum: RGD PMID:28724746 RGD:151356966
G MAPK1 mitogen-activated protein kinase 1 ISO protein:decreased phosphorylation:cornea RGD PMID:21330660 PMID:22045654 RGD:5131482 RGD:7243969 NCBI chr19:4,246,144...4,352,648
Ensembl chr19:4,246,122...4,353,325 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 ISO protein:decreased phosphorylation:cornea RGD PMID:21330660 RGD:5131482 NCBI chr 5:26,536,471...26,545,666
Ensembl chr 5:26,536,532...26,546,461 		JBrowse link
G MAPT microtubule associated protein tau treatment ISO RGD PMID:28400135 RGD:13800903 NCBI chr16:59,894,400...60,020,723
Ensembl chr16:59,890,221...59,955,612 		JBrowse link
G MAS1 MAS1 proto-oncogene, G protein-coupled receptor ISO mRNA:increased expression:renal cortex (rat) RGD PMID:18679036 RGD:2313799 NCBI chr13:87,520,860...87,523,523
Ensembl chr13:87,521,947...87,523,098 		JBrowse link
G MBP myelin basic protein ISO RGD PMID:23667870 RGD:7327197 NCBI chr18:2,844,154...2,996,640
Ensembl chr18:2,868,795...2,997,046 		JBrowse link
G MDM2 MDM2 proto-oncogene ISO protein:increased degradation:myocardium RGD PMID:23530877 RGD:10412313 NCBI chr11:64,434,203...64,465,490
Ensembl chr11:64,434,261...64,469,890 		JBrowse link
G MEF2A myocyte enhancer factor 2A ISO mRNA:increased expression:heart RGD PMID:18413674 RGD:2312263 NCBI chr29:18,150,315...18,312,975
Ensembl chr29:18,150,854...18,309,247 		JBrowse link
G MEF2C myocyte enhancer factor 2C ISO mRNA:increased expression:heart RGD PMID:18413674 RGD:2312263 NCBI chr 4:82,702,378...82,887,491
Ensembl chr 4:82,706,738...82,788,152 		JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase ISO mRNA, protein:increased expression:kidney, tubule, epithelium (rat) RGD PMID:8997394 RGD:2317555 NCBI chr21:85,370,574...85,486,405
Ensembl chr21:85,397,645...85,488,093 		JBrowse link
G MFGE8 milk fat globule EGF and factor V/VIII domain containing ISO CTD Direct Evidence: marker/mechanism CTD PMID:21505870
G MFN2 mitofusin 2 treatment ISO protein:increased expression:heart, mitochondrion (rat) RGD PMID:27998959 PMID:28483572 RGD:12910731 RGD:12910739 NCBI chr20:119,787,700...119,818,455
Ensembl chr20:119,787,370...119,816,693 		JBrowse link
G MIF macrophage migration inhibitory factor ISO protein:increased expression:pancreatic islet RGD PMID:15790730 RGD:1641951 NCBI chr19:7,000,837...7,001,700
Ensembl chr19:7,000,793...7,001,757 		JBrowse link
G MMP1 matrix metallopeptidase 1 ISO protein:increased expression:periodontal ligament, alveolar bone of mandible (rat) RGD PMID:20082587 RGD:7207377 NCBI chr 1:94,167,507...94,177,357
Ensembl chr 1:94,167,219...94,176,767 		JBrowse link
G MMP2 matrix metallopeptidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21963884 NCBI chr 5:41,264,382...41,291,657
Ensembl chr 5:41,264,354...41,291,004 		JBrowse link
G MMP9 matrix metallopeptidase 9 treatment ISO protein:increased expression:kidney
mRNA:increased expression:retina
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:17569353 PMID:21963884 PMID:22191573 PMID:23089644 PMID:23423566 RGD:2290354 RGD:8547881 RGD:8547974 NCBI chr 2:17,867,267...17,874,757
Ensembl chr 2:17,867,177...17,874,712 		JBrowse link
G MPO myeloperoxidase ISO CTD Direct Evidence: marker/mechanism
protein:increased activity:liver:		 CTD
RGD		 PMID:18436980 PMID:20388520 RGD:2317971 NCBI chr16:35,120,194...35,130,851
Ensembl chr16:35,120,581...35,130,671 		JBrowse link
G MTHFR methylenetetrahydrofolate reductase ISO protein:decreased activity:kidney (rat) RGD PMID:9836532 RGD:6893689 NCBI chr20:119,987,667...120,003,611
Ensembl chr20:119,990,133...120,002,950 		JBrowse link
G MTOR mechanistic target of rapamycin kinase ISO protein:hyperphosphorylation:muscle RGD PMID:28536139 RGD:13506787 NCBI chr20:120,522,667...120,678,988
Ensembl chr20:120,525,737...120,679,020 		JBrowse link
G MTR 5-methyltetrahydrofolate-homocysteine methyltransferase ISO protein:decreased activity:liver RGD PMID:18936199 RGD:7207081 NCBI chr25:73,935,666...74,039,872
Ensembl chr25:73,935,225...74,038,741 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor ISO mRNA:increased expression:renal cortex (rat) RGD PMID:18030501 RGD:7207459 NCBI chr 8:122,282,989...122,288,392
Ensembl chr 8:122,282,630...122,288,384 		JBrowse link
G NAMPT nicotinamide phosphoribosyltransferase ISO protein:decreased expression:fat cell RGD PMID:18410550 RGD:2311099 NCBI chr21:75,160,748...75,195,781
Ensembl chr21:75,158,596...75,196,025 		JBrowse link
G NCF1 neutrophil cytosolic factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14871415 PMID:16380483 NCBI chr28:8,334,172...8,349,828
Ensembl chr28:8,332,772...8,349,804 		JBrowse link
G NCF2 neutrophil cytosolic factor 2 ISO protein:altered localization:glomerulus
protein:increased expression:heart, membrane fraction		 RGD PMID:14514646 PMID:18061195 RGD:2314434 RGD:2314451 NCBI chr25:45,770,370...45,807,064
Ensembl chr25:45,770,641...45,806,515 		JBrowse link
G NDUFS2 NADH:ubiquinone oxidoreductase core subunit S2 ISO protein:decreased expression:dorsal root ganglia (rat) RGD PMID:20876714 RGD:6484699 NCBI chr20:2,767,864...2,780,336
Ensembl chr20:2,768,064...2,780,704 		JBrowse link
G NDUFS3 NADH:ubiquinone oxidoreductase core subunit S3 ISO protein:decreased expression:dorsal root ganglia (rat)
mRNA, protein:decreased expression:brain		 RGD PMID:20876714 PMID:22387129 RGD:13824971 RGD:6484699 NCBI chr 1:17,735,040...17,740,508
Ensembl chr 1:17,733,645...17,745,677 		JBrowse link
G NEFH neurofilament heavy chain treatment ISO RGD PMID:12941778 RGD:9698428 NCBI chr19:12,357,982...12,375,449 JBrowse link
G NEFM neurofilament medium chain treatment ISO RGD PMID:12941778 RGD:9698428 NCBI chr 8:23,039,187...23,044,668
Ensembl chr 8:23,039,282...23,044,667 		JBrowse link
G NEUROD1 neuronal differentiation 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16123366 NCBI chr10:67,203,714...67,208,644
Ensembl chr10:67,205,141...67,206,211 		JBrowse link
G NEUROG3 neurogenin 3 ISO RGD PMID:19819964 RGD:2313774 NCBI chr 9:61,743,562...61,746,884
Ensembl chr 9:61,744,332...61,744,979 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 treatment ISO protein:increased localization:blood, mononuclear cell, nucleus RGD PMID:22869588 PMID:23331247 PMID:24740568 RGD:10412694 RGD:10412720 RGD:7244270 NCBI chr10:62,789,647...62,825,651
Ensembl chr10:62,790,124...62,825,339 		JBrowse link
G NFKB2 nuclear factor kappa B subunit 2 ISO RGD PMID:18633731 RGD:2298775 NCBI chr 9:95,426,193...95,434,560
Ensembl chr 9:95,427,785...95,434,570 		JBrowse link
G NFKBIA NFKB inhibitor alpha treatment ISO protein:decreased expression:kidney RGD PMID:20188823 PMID:22483164 RGD:10413864 RGD:10413873 NCBI chr24:12,211,619...12,216,185
Ensembl chr24:12,210,281...12,214,854 		JBrowse link
G NGF nerve growth factor treatment ISO protein:increased expression:retina
mRNA, protein:decreased expression:sciatic nerve
protein:decreased processing:hippocampus		 RGD PMID:19149268 PMID:21136036 PMID:25728260 PMID:26282349 RGD:2303795 RGD:402463971 RGD:402463972 RGD:5144144 NCBI chr20:18,361,795...18,413,987
Ensembl chr20:18,413,108...18,413,833 		JBrowse link
G NGFR nerve growth factor receptor ISO protein:increased expression:retina
protein:decreased expression:telencephalon		 RGD PMID:21136036 PMID:26282349 RGD:402463971 RGD:5144144 NCBI chr16:69,894,000...69,914,209
Ensembl chr16:69,894,139...69,912,189 		JBrowse link
G NKX6-1 NK6 homeobox 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16123366 NCBI chr 7:32,846,436...32,851,526
Ensembl chr 7:32,846,528...32,851,447 		JBrowse link
G NOS1 nitric oxide synthase 1 ISO protein:decreased dimerization:stomach RGD PMID:17347455 RGD:1642144 NCBI chr11:112,642,374...112,673,882 JBrowse link
G NOS2 nitric oxide synthase 2 no_association ISO protein:increased expression:renal glomerulus (rat)
associated with Infarction, Middle Cerebral Artery; protein:increased expression:brain (rat)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:9349594 PMID:16380483 PMID:16959961 PMID:21993016 RGD:5509105 RGD:5509107 NCBI chr16:21,533,011...21,576,645
Ensembl chr16:21,533,484...21,574,257 		JBrowse link
G NOS3 nitric oxide synthase 3 treatment ISO protein:decreased expression:thoracic aorta (mouse)
CTD Direct Evidence: marker/mechanism
protein:increased expression:heart		 RGD
CTD		 PMID:11696579 PMID:14871415 PMID:15490108 PMID:16959961 PMID:18266981 More... RGD:13450939 RGD:2292100 RGD:4892007 RGD:7777108 NCBI chr21:119,174,829...119,196,840 JBrowse link
G NOX4 NADPH oxidase 4 ISO protein:increased expression:aorta RGD PMID:19686728 RGD:2324658 NCBI chr 1:80,470,418...80,642,513
Ensembl chr 1:80,470,826...80,642,722 		JBrowse link
G NPC1L1 NPC1 like intracellular cholesterol transporter 1 ISO mRNA:increased expression:intestine, liver RGD PMID:17292734 RGD:1642185 NCBI chr21:14,129,413...14,163,916
Ensembl chr21:14,130,767...14,163,907 		JBrowse link
G NPPA natriuretic peptide A ISO protein:decreased expression:retina
protein:increased expression:plasma, kidney, heart;		 RGD PMID:15789000 PMID:17151304 RGD:1580773 RGD:7248602 NCBI chr20:119,942,412...119,946,211
Ensembl chr20:119,944,532...119,945,917 		JBrowse link
G NPPB natriuretic peptide B ISO protein:increased expression:atrium myocardium, plasma RGD PMID:17151299 RGD:1642199 NCBI chr20:119,930,931...119,933,391
Ensembl chr20:119,932,021...119,933,197 		JBrowse link
G NPY neuropeptide Y ISO protein:increased expression:paraventricular nucleus of hypothalamus RGD PMID:21042571 RGD:10448960 NCBI chr21:34,068,533...34,076,205
Ensembl chr21:34,068,530...34,075,127 		JBrowse link
G NPY1R neuropeptide Y receptor Y1 ISO RGD PMID:18201831 RGD:10448967 NCBI chr 7:109,774,700...109,794,543
Ensembl chr 7:109,774,918...109,776,905 		JBrowse link
G NPY2R neuropeptide Y receptor Y2 ISO RGD PMID:18201831 RGD:10448967 NCBI chr 7:101,696,081...101,773,782
Ensembl chr 7:101,770,551...101,771,696 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 ISO CTD Direct Evidence: therapeutic CTD PMID:23458895 NCBI chr 5:57,676,547...57,695,434
Ensembl chr 5:57,675,981...57,716,599 		JBrowse link
G NR1H3 nuclear receptor subfamily 1 group H member 3 ISO DNA, mRNA, protein:hypomethylation, increased expression:promoter, heart RGD PMID:21136146 RGD:13831298 NCBI chr 1:18,041,495...18,061,196
Ensembl chr 1:18,041,830...18,051,501 		JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 ISO mRNA:decreased expression:liver RGD PMID:15047603 RGD:1625080 NCBI chr11:95,792,428...95,877,989
Ensembl chr11:95,792,996...95,878,293 		JBrowse link
G NR1I3 nuclear receptor subfamily 1 group I member 3 treatment ISO RGD PMID:20636876 RGD:9835393 NCBI chr20:2,724,843...2,752,999
Ensembl chr20:2,744,908...2,756,658 		JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 treatment ISO protein:increased expression:placenta RGD PMID:21744335 PMID:26883980 RGD:12879479 RGD:14695543 NCBI chr23:45,904,926...46,031,804
Ensembl chr23:45,904,873...46,031,125 		JBrowse link
G NRP1 neuropilin 1 ISO mRNA:decreased expression:skeletal muscle RGD PMID:16816123 RGD:2313725 NCBI chr 9:32,474,787...32,632,746
Ensembl chr 9:32,474,309...32,633,101 		JBrowse link
G NT5E 5'-nucleotidase ecto ISO protein:increased expression:cerebral cortex, synaptosome (rat) RGD PMID:19723569 RGD:5134343 NCBI chr13:10,115,591...10,162,178
Ensembl chr13:10,116,161...10,160,414 		JBrowse link
G NTRK1 neurotrophic receptor tyrosine kinase 1 ISO protein:increased tyrosine nitration, decreased tyrosine phosphorylation:retina RGD PMID:21136036 PMID:22044876 RGD:5144144 RGD:5684337 NCBI chr20:6,987,903...7,027,381
Ensembl chr20:6,987,905...7,008,670 		JBrowse link
G NTRK2 neurotrophic receptor tyrosine kinase 2 treatment ISO RGD PMID:30816461 RGD:596936233 NCBI chr12:95,477,612...95,836,734
Ensembl chr12:95,479,447...95,620,364 		JBrowse link
G NTRK3 neurotrophic receptor tyrosine kinase 3 ISO mRNA:decreased expression:dorsal root ganglion RGD PMID:9541170 RGD:2325654 NCBI chr29:6,441,824...6,831,029
Ensembl chr29:6,447,256...6,830,526 		JBrowse link
G OGG1 8-oxoguanine DNA glycosylase ISO protein:altered localization:pancreatic islet RGD PMID:15677345 PMID:18599524 PMID:18676009 RGD:2317137 RGD:8657146 RGD:8657153 NCBI chr22:45,757,414...45,763,690 JBrowse link
G OGT O-linked N-acetylglucosamine (GlcNAc) transferase treatment ISO RGD PMID:15561949 RGD:9590198 NCBI chr  X:61,351,047...61,393,541
Ensembl chr  X:61,351,054...61,394,305 		JBrowse link
G OPRK1 opioid receptor kappa 1 ISO protein:increased expression:sciatic nerve, peroneal nerve: RGD PMID:16924480 RGD:9834947 NCBI chr 8:49,337,308...49,364,724
Ensembl chr 8:49,341,427...49,362,947 		JBrowse link
G OPRM1 opioid receptor mu 1 ISO RGD PMID:16901587 RGD:2316626 NCBI chr13:81,568,295...81,650,005
Ensembl chr13:81,568,732...81,625,088 		JBrowse link
G OSBP oxysterol binding protein ISO protein:increased tyrosine phosphorylation:aorta RGD PMID:18230613 RGD:2291921 NCBI chr 1:14,009,735...14,053,232
Ensembl chr 1:14,010,020...14,051,605 		JBrowse link
G OTC ornithine transcarbamylase ISO protein:decreased activity:small intestine (rat) RGD PMID:9628242 RGD:4144123 NCBI chr  X:35,494,334...35,570,923
Ensembl chr  X:35,494,287...35,570,845 		JBrowse link
G OXCT1 3-oxoacid CoA-transferase 1 ISO protein:decreased activity:heart, mitochondrion (rat) RGD PMID:3548709 RGD:2326100 NCBI chr 4:40,477,983...40,620,971 JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 ISO RGD PMID:18657544 RGD:2312287 NCBI chr25:3,350,798...3,405,040 JBrowse link
G PAX6 paired box 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16123366 NCBI chr 1:33,386,165...33,414,605
Ensembl chr 1:33,392,970...33,414,587 		JBrowse link
G PC pyruvate carboxylase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16123366 NCBI chr 1:7,310,738...7,418,357
Ensembl chr 1:7,357,246...7,417,998 		JBrowse link
G PCK1 phosphoenolpyruvate carboxykinase 1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:17651728 PMID:20363216 RGD:2311641 NCBI chr 2:6,550,806...6,556,499
Ensembl chr 2:6,549,652...6,556,478 		JBrowse link
G PCSK1 proprotein convertase subtilisin/kexin type 1 ISO mRNA, protein:increased expression:spleen, spleen white pulp (rat)
protein:increased expression:pancreatic alpha cell (mouse)
mRNA, protein:increased expression:spleen (mouse)		 RGD PMID:11730986 PMID:17698597 RGD:2308905 RGD:2308931 NCBI chr 4:90,246,413...90,289,148
Ensembl chr 4:90,248,598...90,289,089 		JBrowse link
G PCSK2 proprotein convertase subtilisin/kexin type 2 ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:spleen		 CTD
RGD		 PMID:11730986 PMID:16123366 RGD:2308905 NCBI chr 2:46,293,983...46,548,902
Ensembl chr 2:46,294,005...46,549,609 		JBrowse link
G PDE3A phosphodiesterase 3A ISO mRNA, protein:increased expression:mesenteric artery RGD PMID:12793980 RGD:2300416 NCBI chr11:20,235,814...20,545,740
Ensembl chr11:20,236,430...20,540,900 		JBrowse link
G PDE5A phosphodiesterase 5A ISO RGD PMID:19542492 RGD:2314461 NCBI chr 7:66,826,316...66,955,220
Ensembl chr 7:66,826,315...66,955,036 		JBrowse link
G PDGFB platelet derived growth factor subunit B ISO mRNA:decreased expression:retina
mRNA: increased expression: mesenteric artery
mRNA:increased expression:glomerulus
mRNA:increased expression:retina		 RGD PMID:8094359 PMID:9763208 PMID:12606528 PMID:14685146 PMID:21367419 RGD:10449499 RGD:1581759 RGD:2311648 RGD:2311650 RGD:6483042 NCBI chr19:21,865,792...21,888,068
Ensembl chr19:21,863,768...21,886,395 		JBrowse link
G PDGFRB platelet derived growth factor receptor beta ISO protein:increased expression:glomerulus RGD PMID:10802145 RGD:2311654 NCBI chr23:52,724,061...52,766,264
Ensembl chr23:52,724,005...52,766,234 		JBrowse link
G PDK4 pyruvate dehydrogenase kinase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14563825 NCBI chr21:53,445,607...53,458,729
Ensembl chr21:53,445,457...53,460,776 		JBrowse link
G PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2 ISO RGD PMID:12765946 RGD:1582364 NCBI chr 5:52,575,280...52,583,614
Ensembl chr 5:52,580,423...52,582,009 		JBrowse link
G PDX1 pancreatic and duodenal homeobox 1 ISO protein:increased expression:pancreatic delta cell (rat)
CTD Direct Evidence: marker/mechanism
protein:increased expression:pancreas (rat)		 RGD
CTD		 PMID:14988244 PMID:15561947 PMID:16123366 PMID:17226789 PMID:17235568 More... RGD:1357906 RGD:2311224 RGD:2311225 RGD:2311226 RGD:2311311 NCBI chr 3:7,038,088...7,046,593
Ensembl chr 3:7,041,466...7,045,976 		JBrowse link
G PDYN prodynorphin ISO protein:increased expression:sciatic nerve, peroneal nerve, tibial nerve, footpad skin: RGD PMID:16924480 RGD:9834947 NCBI chr 2:54,535,516...54,551,085
Ensembl chr 2:54,535,240...54,551,104 		JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 ISO protein:decreased expression:corpus callosum, endothelium (rat) RGD PMID:21967314 RGD:6771179 NCBI chr16:56,863,763...56,947,479
Ensembl chr16:56,880,934...56,950,999 		JBrowse link
G PEMT phosphatidylethanolamine N-methyltransferase ISO protein:increased expression:liver RGD PMID:17116711 RGD:1642370 NCBI chr16:16,540,096...16,626,251
Ensembl chr16:16,539,985...16,611,279 		JBrowse link
G PFAS phosphoribosylformylglycinamidine synthase ISO protein:increased activity:liver (rat) RGD PMID:3043317 RGD:5135485 NCBI chr16:7,618,952...7,639,700
Ensembl chr16:7,623,817...7,638,594 		JBrowse link
G PFKM phosphofructokinase, muscle ISO CTD Direct Evidence: marker/mechanism CTD PMID:14563825 NCBI chr11:44,332,857...44,378,273
Ensembl chr11:44,334,605...44,377,877 		JBrowse link
G PGF placental growth factor ISO mRNA, protein:decreased expression:placenta, trophoblast cell RGD PMID:17917370 RGD:6483782 NCBI chr24:52,160,904...52,174,493
Ensembl chr24:52,161,787...52,173,989 		JBrowse link
G PHKA1 phosphorylase kinase regulatory subunit alpha 1 ISO RGD PMID:11692172 RGD:1599897 NCBI chr  X:62,397,726...62,528,695
Ensembl chr  X:62,397,739...62,528,708 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 ISO protein:increased expression:gastrocnemius (rat) RGD PMID:18430054 RGD:2307338 NCBI chr 4:64,321,296...64,406,188
Ensembl chr 4:64,321,078...64,406,519 		JBrowse link
G PKLR pyruvate kinase L/R ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:16900249 PMID:20363216 RGD:1625589 NCBI chr20:8,540,228...8,547,184
Ensembl chr20:8,540,763...8,545,884 		JBrowse link
G PLCB3 phospholipase C beta 3 ISO protein:decreased expression:heart left ventricle RGD PMID:15362504 RGD:2314509 NCBI chr 1:9,964,850...9,982,573
Ensembl chr 1:9,966,618...9,982,317 		JBrowse link
G PLCG1 phospholipase C gamma 1 ISO protein:increased tyrosine phosphorylation:lens RGD PMID:17612968 RGD:2299877 NCBI chr 2:22,599,547...22,638,394 JBrowse link
G PNMT phenylethanolamine N-methyltransferase ISO protein:increased expression:adrenal gland (rat) RGD PMID:16396986 RGD:5130724 NCBI chr16:66,496,290...66,498,840
Ensembl chr16:66,496,027...66,499,111 		JBrowse link
G POLG DNA polymerase gamma, catalytic subunit ISO mRNA,protein:decreased expression:retina,mitochondrion: RGD PMID:22229649 PMID:22743328 RGD:8694093 RGD:8694187 NCBI chr29:7,864,319...7,881,577
Ensembl chr29:7,863,277...7,882,068 		JBrowse link
G POLG2 DNA polymerase gamma 2, accessory subunit ISO mRNA,protein:decreased expression:retina,mitochondrion: RGD PMID:22229649 RGD:8694187 NCBI chr16:56,773,867...56,794,571
Ensembl chr16:56,776,330...56,794,654 		JBrowse link
G PON1 paraoxonase 1 ISO RGD PMID:18358245 RGD:2313268 NCBI chr21:53,713,434...53,739,658
Ensembl chr21:53,714,012...53,739,875 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:12967931 PMID:14563825 PMID:23090186
G PPARD peroxisome proliferator activated receptor delta ISO mRNA, protein:decreased expression:heart RGD PMID:18573863 RGD:2313781 NCBI chr17:36,695,546...36,779,554
Ensembl chr17:36,695,494...36,779,577 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma ISO protein:decreased expression:retina
mRNA:altered expression:aorta, kidney cortex, retina
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:12967931 PMID:16123366 PMID:18641696 PMID:18806296 PMID:21757225 RGD:2301844 RGD:2301849 NCBI chr22:48,262,743...48,407,415
Ensembl chr22:48,275,600...48,407,418 		JBrowse link
G PPARGC1A PPARG coactivator 1 alpha treatment ISO mRNA:decreased expression:pancreatic islet
protein:decreased expression:dorsal root ganglia (mouse)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:14563825 PMID:18270681 PMID:19520786 PMID:22561641 PMID:23272147 RGD:2311391 RGD:2311445 RGD:7241845 RGD:7242175 NCBI chr27:25,882,385...26,563,530
Ensembl chr27:26,465,499...26,564,582 		JBrowse link
G PPAT phosphoribosyl pyrophosphate amidotransferase ISO protein:increased activity:kidney (rat) RGD PMID:2451505 RGD:5135016 NCBI chr 7:12,201,434...12,242,418
Ensembl chr 7:12,191,784...12,243,488 		JBrowse link
G PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2 treatment ISO RGD PMID:32535406 RGD:401850547 NCBI chr20:76,258,063...76,319,512
Ensembl chr20:76,259,763...76,319,430 		JBrowse link
G PRKCA protein kinase C alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:12198386 NCBI chr16:54,638,548...55,144,372
Ensembl chr16:54,642,729...54,948,256 		JBrowse link
G PRKCB protein kinase C beta ISO protein:increased expression:myocardium RGD PMID:17250813 RGD:1625511 NCBI chr 5:21,558,608...21,940,536
Ensembl chr 5:21,558,441...21,943,864 		JBrowse link
G PRKCD protein kinase C delta ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:kidney		 CTD
RGD		 PMID:11576956 PMID:12198386 RGD:1642532 NCBI chr22:14,561,401...14,592,877
Ensembl chr22:14,565,282...14,592,873 		JBrowse link
G PRKCE protein kinase C epsilon ISO CTD Direct Evidence: marker/mechanism CTD PMID:12198386 NCBI chr14:61,022,903...61,570,390
Ensembl chr14:61,026,017...61,242,343 		JBrowse link
G PRKCI protein kinase C iota ISO protein:increased expression:ventricle myocardium, membrane fraction RGD PMID:14691046 RGD:2314944 NCBI chr15:19,103,682...19,180,689 JBrowse link
G PRKG1 protein kinase cGMP-dependent 1 treatment ISO protein:decreased expression:aorta RGD PMID:15939056 PMID:20186099 RGD:7775064 RGD:7777110 NCBI chr 9:78,858,269...80,188,163 JBrowse link
G PRKRA protein activator of interferon induced protein kinase EIF2AK2 ISO RGD PMID:21897745 RGD:7777145 NCBI chr10:63,982,784...64,003,919 JBrowse link
G PSMB9 proteasome 20S subunit beta 9 ISO mRNA:increased expression:hippocampus (rat) RGD PMID:20968039 RGD:9850284 NCBI chr17:39,246,356...39,251,852
Ensembl chr17:39,245,854...39,251,842 		JBrowse link
G PTGIS prostaglandin I2 synthase treatment ISO RGD PMID:8888351 RGD:401960094 NCBI chr 2:14,420,318...14,484,667
Ensembl chr 2:14,441,983...14,488,264 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO protein:decreased expression:spinal cord RGD PMID:12086957 RGD:727386 NCBI chr12:17,195,403...17,218,450
Ensembl chr12:17,192,628...17,218,315 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO protein:increased expression:lung
CTD Direct Evidence: marker/mechanism
protein:increased expression:sciatic nerve		 RGD
CTD		 PMID:14514642 PMID:17720896 PMID:18706904 PMID:21414306 PMID:21521772 RGD:1642588 RGD:2300222 RGD:5135278 NCBI chr25:42,733,535...42,742,463
Ensembl chr25:42,734,771...42,742,429 		JBrowse link
G PTPN1 protein tyrosine phosphatase non-receptor type 1 ISO protein:increased activity:retina (mouse) RGD PMID:19029027 RGD:401965415 NCBI chr 2:13,385,681...13,459,180
Ensembl chr 2:13,387,727...13,459,105 		JBrowse link
G PTPRN protein tyrosine phosphatase receptor type N severity ISO RGD PMID:19513530 RGD:2313594 NCBI chr10:105,196,508...105,216,665
Ensembl chr10:105,196,505...105,216,525 		JBrowse link
G PTPRU protein tyrosine phosphatase receptor type U ISO protein:decreased expression:glomerulus RGD PMID:16539708 RGD:1642656 NCBI chr20:103,497,681...103,586,494
Ensembl chr20:103,498,839...103,586,348 		JBrowse link
G PYGM glycogen phosphorylase, muscle associated ISO protein:increased expression:sarcoplasmic reticulum RGD PMID:11692172 RGD:1599897 NCBI chr 1:9,474,539...9,490,612
Ensembl chr 1:9,475,622...9,491,500 		JBrowse link
G QDPR quinoid dihydropteridine reductase ISO protein:decreased activity:brain (rat) RGD PMID:2758679 RGD:5128601 NCBI chr27:32,697,582...32,723,616
Ensembl chr27:32,697,599...32,723,016 		JBrowse link
G RAMP2 receptor activity modifying protein 2 ISO mRNA:increased expression:kidney RGD PMID:14717924 RGD:1642701 NCBI chr16:63,526,915...63,529,697
Ensembl chr16:63,526,305...63,528,767 		JBrowse link
G RAP1B RAP1B, member of RAS oncogene family ISO protein:increased expression:renal glomerulus (rat) RGD PMID:12196513 RGD:10041023 NCBI chr11:64,240,501...64,290,515
Ensembl chr11:64,240,651...64,286,727 		JBrowse link
G RASGRF1 Ras protein specific guanine nucleotide releasing factor 1 ISO protein:decreased expression:brain, membrane (rat) RGD PMID:19002579 RGD:10003129 NCBI chr26:4,298,091...4,431,606
Ensembl chr26:4,299,116...4,432,420 		JBrowse link
G RBFOX2 RNA binding fox-1 homolog 2 ISO mRNA:splice variant: heart (mouse)
protein:increased expression:heart, cytoplasm (mouse)		 RGD PMID:24151077 PMID:27239029 RGD:329845874 RGD:329848997 NCBI chr19:18,507,184...18,801,535 JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit ISO protein:increased expression:nucleus, skeletal muscle, liver
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:18500427 PMID:18633731 PMID:22138235 RGD:2298775 RGD:2298780 NCBI chr 1:8,576,059...8,585,561
Ensembl chr 1:8,576,542...8,586,516 		JBrowse link
G REN renin ISO CTD Direct Evidence: marker/mechanism CTD PMID:18829990 NCBI chr25:25,159,816...25,193,620
Ensembl chr25:25,183,037...25,193,420 		JBrowse link
G RGN regucalcin ISO protein:decreased expression:liver RGD PMID:9062895 RGD:9590177 NCBI chr  X:44,282,825...44,299,027
Ensembl chr  X:44,285,601...44,299,258 		JBrowse link
G RHOA ras homolog family member A ISO RGD PMID:17589825 RGD:1642825 NCBI chr22:10,757,381...10,809,257
Ensembl chr22:10,757,337...10,772,704 		JBrowse link
G RPE65 retinoid isomerohydrolase RPE65 ISO mRNA:decreased expression:retina (rat) RGD PMID:21862641 RGD:9585653 NCBI chr20:64,662,777...64,684,178
Ensembl chr20:64,664,358...64,683,211 		JBrowse link
G RYR2 ryanodine receptor 2 ISO RGD PMID:17027851 RGD:1599247 NCBI chr25:74,169,024...74,951,371
Ensembl chr25:74,389,122...74,953,451 		JBrowse link
G S100A6 S100 calcium binding protein A6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16123366 NCBI chr20:10,267,708...10,269,361
Ensembl chr20:10,267,556...10,269,405 		JBrowse link
G S100B S100 calcium binding protein B ISO protein:altered expression:hippocampus, astrocyte
protein:increased expression:cerebellum, cerebral cortex, hippocampus		 RGD PMID:14583344 PMID:18708122 RGD:5508821 RGD:5508836 NCBI chr 2:90,188,820...90,194,986
Ensembl chr 2:90,188,639...90,195,023 		JBrowse link
G S1PR2 sphingosine-1-phosphate receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22406263 NCBI chr 6:9,281,130...9,291,705
Ensembl chr 6:9,283,529...9,284,590 		JBrowse link
G S1PR4 sphingosine-1-phosphate receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22406263 NCBI chr 6:2,941,446...2,943,452
Ensembl chr 6:2,941,901...2,943,055 		JBrowse link
G S1PR5 sphingosine-1-phosphate receptor 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22406263 NCBI chr 6:9,537,083...9,542,610
Ensembl chr 6:9,538,156...9,539,352 		JBrowse link
G SCAP SREBF chaperone ISO RGD PMID:20973890 RGD:5490977 NCBI chr22:8,821,809...8,887,538
Ensembl chr22:8,818,980...8,850,202 		JBrowse link
G SCD stearoyl-CoA desaturase treatment ISO RGD PMID:32535406 RGD:401850547 NCBI chr 9:93,380,812...93,398,860
Ensembl chr 9:93,380,914...93,398,912 		JBrowse link
G SCP2 sterol carrier protein 2 treatment ISO RGD PMID:7628371 RGD:9850252 NCBI chr20:79,868,825...79,993,906
Ensembl chr20:79,865,332...79,993,835 		JBrowse link
G SELP selectin P treatment ISO RGD PMID:18095572 RGD:2312301 NCBI chr25:59,420,910...59,465,140
Ensembl chr25:59,433,333...59,462,598 		JBrowse link
G SERPINC1 serpin family C member 1 treatment ISO RGD PMID:22309505 PMID:24671746 RGD:11035271 RGD:11035293 NCBI chr25:55,271,823...55,289,855 JBrowse link
G SERPINE1 serpin family E member 1 ISO protein:increased expression:heart (mouse)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:20630999 PMID:21757225 RGD:8547862 NCBI chr28:12,047,520...12,060,662
Ensembl chr28:12,047,529...12,060,202 		JBrowse link
G SERPINF1 serpin family F member 1 ISO protein:decreased expression:platelet RGD PMID:19237211 RGD:2312338 NCBI chr16:1,408,453...1,424,197 JBrowse link
G SI sucrase-isomaltase ISO protein:increased expression:small intestine mucosa RGD PMID:12940455 RGD:1625543 NCBI chr15:24,480,060...24,582,468
Ensembl chr15:24,482,865...24,582,394 		JBrowse link
G SIRT1 sirtuin 1 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:22179968 PMID:23090186 PMID:23792339 RGD:9586012 NCBI chr 9:63,463,059...63,497,893
Ensembl chr 9:63,462,389...63,497,867 		JBrowse link
G SLC1A3 solute carrier family 1 member 3 treatment ISO RGD PMID:23595285 RGD:401794586 NCBI chr 4:35,473,425...35,557,118
Ensembl chr 4:35,473,658...35,557,138 		JBrowse link
G SLC22A1 solute carrier family 22 member 1 ISO RGD PMID:14718608 RGD:2317435 NCBI chr13:87,744,600...87,780,846
Ensembl chr13:87,745,023...87,781,073 		JBrowse link
G SLC22A2 solute carrier family 22 member 2 ISO protein:decreased expression:kidney RGD PMID:19356064 RGD:2312728 NCBI chr13:87,835,077...87,881,410
Ensembl chr13:87,833,430...87,881,081 		JBrowse link
G SLC28A2 solute carrier family 28 member 2 ISO RGD PMID:16014043 RGD:2317455 NCBI chr26:37,927,200...37,956,729 JBrowse link
G SLC28A3 solute carrier family 28 member 3 ISO RGD PMID:16014043 RGD:2317455 NCBI chr12:95,088,902...95,179,201
Ensembl chr12:95,091,301...95,127,745 		JBrowse link
G SLC29A1 solute carrier family 29 member 1 (Augustine blood group) ISO mRNA:decreased expression:cardiac muscle cell RGD PMID:16873415 RGD:2316941 NCBI chr17:27,934,537...27,949,120
Ensembl chr17:27,931,945...27,949,006 		JBrowse link
G SLC2A1 solute carrier family 2 member 1 treatment ISO mRNA, protein:decreased expression:brain RGD PMID:8345816 PMID:17935675 RGD:12879858 RGD:2313617 NCBI chr20:89,974,567...90,007,977
Ensembl chr20:90,002,030...90,008,033 		JBrowse link
G SLC2A2 solute carrier family 2 member 2 ISO mRNA:increased expression:kidney
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:16123366 PMID:19433262 RGD:2312358 NCBI chr15:18,434,370...18,466,331
Ensembl chr15:18,434,916...18,467,352 		JBrowse link
G SLC2A3 solute carrier family 2 member 3 ISO mRNA, protein:decreased expression:brain RGD PMID:17935675 RGD:2313617 NCBI chr11:8,004,861...8,023,023 JBrowse link
G SLC2A4 solute carrier family 2 member 4 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:11947963 PMID:14563825 PMID:18266981 PMID:19252289 PMID:22138235 RGD:2313621 NCBI chr16:6,654,626...6,660,640
Ensembl chr16:6,654,608...6,661,495 		JBrowse link
G SLC37A4 solute carrier family 37 member 4 ISO protein:increased expression:liver RGD PMID:10567346 RGD:1625641 NCBI chr 1:110,396,133...110,402,737
Ensembl chr 1:110,395,612...110,401,358 		JBrowse link
G SLC38A2 solute carrier family 38 member 2 ISO RGD PMID:11798158 RGD:9999213 NCBI chr11:42,580,934...42,595,484
Ensembl chr11:42,580,913...42,595,484 		JBrowse link
G SLC8A1 solute carrier family 8 member A1 ISO mRNA, protein:decreased expression:cardiac muscle cell RGD PMID:10944172 RGD:1642714 NCBI chr14:66,813,523...67,210,261 JBrowse link
G SLC9A1 solute carrier family 9 member A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20003708 NCBI chr20:105,613,289...105,670,868
Ensembl chr20:105,613,338...105,674,208 		JBrowse link
G SMAD1 SMAD family member 1 severity ISO protein:increased expression:glomerulus, urine RGD PMID:16482100 RGD:1643228 NCBI chr 7:92,047,273...92,123,451
Ensembl chr 7:92,079,914...92,123,429 		JBrowse link
G SMARCA4 SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4 treatment ISO RGD PMID:23853776 RGD:9586347 NCBI chr 6:9,943,162...10,044,476 JBrowse link
G SMPD1 sphingomyelin phosphodiesterase 1 ISO protein:decreased expression:gastrocnemius RGD PMID:14983401 RGD:1601347 NCBI chr 1:58,431,677...58,436,233
Ensembl chr 1:58,432,068...58,436,236 		JBrowse link
G SNAP25 synaptosome associated protein 25 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16123366 NCBI chr 2:27,857,093...27,944,487
Ensembl chr 2:27,858,319...27,944,496 		JBrowse link
G SOAT2 sterol O-acyltransferase 2 ISO RGD PMID:15242859 RGD:1581191 NCBI chr11:49,214,295...49,228,268
Ensembl chr11:49,215,034...49,228,244 		JBrowse link
G SOCS3 suppressor of cytokine signaling 3 susceptibility ISO mRNA, protein:increased expression:retina RGD PMID:17562326 PMID:18356406 RGD:2298911 RGD:2313787 NCBI chr16:70,353,099...70,356,401
Ensembl chr16:70,354,746...70,355,423 		JBrowse link
G SOD1 superoxide dismutase 1 ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:hippocampus (rat)
associated with alcohol use disorder; protein:decreased activity;testis, epididymis (rat)		 CTD
RGD		 PMID:20924670 PMID:23090186 PMID:25541261 RGD:405255664 RGD:8655956 NCBI chr 2:60,461,219...60,472,999 JBrowse link
G SOD2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism|therapeutic
protein:increased activity:testes		 CTD
RGD		 PMID:15855331 PMID:19891634 PMID:23090186 RGD:2317382 NCBI chr13:87,284,537...87,297,998
Ensembl chr13:87,280,686...87,297,974 		JBrowse link
G SORD sorbitol dehydrogenase ISO protein:increased expression:liver RGD PMID:15064821 RGD:1601360 NCBI chr26:38,129,236...38,173,867
Ensembl chr26:38,126,911...38,155,381 		JBrowse link
G SOX2 SRY-box transcription factor 2 ISO RGD PMID:23828673 RGD:8661677 NCBI chr15:7,673,581...7,676,812
Ensembl chr15:7,674,867...7,675,826 		JBrowse link
G SPP1 secreted phosphoprotein 1 ISO RGD PMID:16528250 RGD:1581322 NCBI chr 7:36,337,165...36,344,927
Ensembl chr 7:36,338,386...36,344,407 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 treatment ISO mRNA, protein:increased expression:renal proximal tubule, epithelial cell
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:10900012 PMID:19048273 PMID:23090186 PMID:32535406 RGD:2308804 RGD:401850547 NCBI chr16:16,847,603...16,874,239
Ensembl chr16:16,845,491...16,859,554 		JBrowse link
G SSTR1 somatostatin receptor 1 ISO RGD PMID:7956902 RGD:2325008 NCBI chr24:15,000,190...15,006,757
Ensembl chr24:15,003,116...15,004,291 		JBrowse link
G SSTR2 somatostatin receptor 2 ISO RGD PMID:7956902 RGD:2325008 NCBI chr16:48,462,472...48,470,586
Ensembl chr16:48,464,342...48,465,451 		JBrowse link
G SSTR3 somatostatin receptor 3 ISO RGD PMID:7956902 RGD:2325008 NCBI chr19:19,908,562...19,916,787
Ensembl chr19:19,910,898...19,912,154 		JBrowse link
G STAR steroidogenic acute regulatory protein ISO mRNA:decreased expression:sciatic nerve (rat) RGD PMID:20826654 RGD:4145530 NCBI chr 8:36,164,891...36,174,424
Ensembl chr 8:36,167,694...36,174,583 		JBrowse link
G STAT1 signal transducer and activator of transcription 1 ISO protein:increased tyrosine phosphorylation:glomerulus RGD PMID:14678947 RGD:1600105 NCBI chr10:76,492,859...76,537,689
Ensembl chr10:76,492,533...76,533,393 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 ISO protein:increased tyrosine phosphorylation:aorta endothelium RGD PMID:18230613 PMID:22660795 RGD:2291921 RGD:8694292 NCBI chr16:63,877,884...63,957,894
Ensembl chr16:63,922,862...63,957,984 		JBrowse link
G STAT4 signal transducer and activator of transcription 4 ISO RGD PMID:10553062 RGD:7207889 NCBI chr10:76,553,626...76,708,540
Ensembl chr10:76,553,606...76,674,928 		JBrowse link
G STRA6 signaling receptor and transporter of retinol STRA6 ISO protein:decreased expression:optic cup (rat) RGD PMID:28734946 RGD:155631297 NCBI chr26:9,275,317...9,311,302
Ensembl chr26:9,278,303...9,311,475 		JBrowse link
G STS steroid sulfatase ISO CTD Direct Evidence: therapeutic CTD PMID:24497646 NCBI chr  X:5,601,746...5,813,916
Ensembl chr  X:5,709,410...5,812,224 		JBrowse link
G TERT telomerase reverse transcriptase ISO RGD PMID:20031167 RGD:2316310 NCBI chr 4:1,082,894...1,119,373
Ensembl chr 4:1,083,384...1,117,468 		JBrowse link
G TF transferrin ISO RGD PMID:17081048 RGD:1601532 NCBI chr15:56,586,311...56,618,304
Ensembl chr15:56,586,104...56,618,149 		JBrowse link
G TGFB1 transforming growth factor beta 1 ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:urine		 CTD
RGD		 PMID:15855808 PMID:17177138 PMID:23090186 RGD:1601583 NCBI chr 6:35,651,583...35,674,387
Ensembl chr 6:35,648,677...35,674,365 		JBrowse link
G TGFB2 transforming growth factor beta 2 ISO protein:increased expression:parotid gland RGD PMID:17574405 RGD:2302087 NCBI chr25:11,163,651...11,259,868
Ensembl chr25:11,163,100...11,258,470 		JBrowse link
G TH tyrosine hydroxylase ISO protein:increased expression:seminal vesicle RGD PMID:17151307 RGD:1601629 NCBI chr 1:1,969,194...1,977,263
Ensembl chr 1:1,966,460...1,977,218 		JBrowse link
G THBS1 thrombospondin 1 ISO RGD PMID:17640965 RGD:2317942 NCBI chr26:43,410,693...43,427,816
Ensembl chr26:43,410,580...43,427,812 		JBrowse link
G TIMM44 translocase of inner mitochondrial membrane 44 ISO protein:decreased expression:retina RGD PMID:23255365 RGD:13463486 NCBI chr 6:7,378,091...7,394,927
Ensembl chr 6:7,377,669...7,396,652 		JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:17192464 PMID:21963884 RGD:2312467
G TIMP2 TIMP metallopeptidase inhibitor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21963884 NCBI chr16:70,819,591...70,850,471
Ensembl chr16:70,819,139...70,850,471 		JBrowse link
G TIMP3 TIMP metallopeptidase inhibitor 3 ISO mRNA:increased expression:glomerulus RGD PMID:8840279 RGD:2312482 NCBI chr19:15,621,609...15,684,118
Ensembl chr19:15,622,431...15,680,449 		JBrowse link
G TJP1 tight junction protein 1 ISO protein:decreased expression:glomerulus RGD PMID:16567508 RGD:2325150 NCBI chr26:52,623,751...52,750,037
Ensembl chr26:52,622,743...52,749,950 		JBrowse link
G TLR2 toll like receptor 2 ISO mRNA:increased expression:gingiva RGD PMID:16740310 PMID:17707128 PMID:24878329 RGD:2312491 RGD:2312684 RGD:597538517 NCBI chr 7:100,239,533...100,565,955
Ensembl chr 7:100,258,441...100,260,795 		JBrowse link
G TLR4 toll like receptor 4 ISO mRNA:increased expression:gingiva RGD PMID:16740310 PMID:24878329 RGD:2312491 RGD:597538517 NCBI chr12:21,873,762...21,885,562
Ensembl chr12:21,871,773...21,885,515 		JBrowse link
G TNC tenascin C ISO RGD PMID:17999372 RGD:4889609 NCBI chr12:24,457,616...24,556,194
Ensembl chr12:24,457,738...24,556,451 		JBrowse link
G TNF tumor necrosis factor treatment ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:liver
protein:increased expression:heart		 CTD
RGD		 PMID:12123627 PMID:12193562 PMID:19220660 PMID:19478208 PMID:20388520 More... RGD:10450575 RGD:2312478 RGD:4142788 RGD:5131250
G TNFRSF1A TNF receptor superfamily member 1A ISO protein:increased expression:liver (rat)
CTD Direct Evidence: therapeutic		 RGD
CTD		 PMID:12193562 PMID:21481476 RGD:5131250 NCBI chr11:6,364,544...6,378,880
Ensembl chr11:6,364,330...6,378,902 		JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B ISO human protein in rat model RGD PMID:21481476 RGD:5131250 NCBI chr20:119,590,621...119,633,562
Ensembl chr20:119,590,325...119,633,497 		JBrowse link
G TNFSF10 TNF superfamily member 10 ISO RGD PMID:12577054 PMID:18649770 PMID:19572802 RGD:2312737 RGD:2312738 RGD:2312744 NCBI chr15:16,934,982...16,953,155
Ensembl chr15:16,934,962...16,954,860 		JBrowse link
G TOMM40 translocase of outer mitochondrial membrane 40 ISO protein:decreased expression:retina RGD PMID:23255365 RGD:13463486 NCBI chr 6:38,363,060...38,375,098
Ensembl chr 6:38,363,176...38,375,218 		JBrowse link
G TOMM70 translocase of outer mitochondrial membrane 70 ISO protein:decreased expression:retina RGD PMID:23255365 RGD:13463486 NCBI chr22:80,477,429...80,516,536
Ensembl chr22:80,477,872...80,516,670 		JBrowse link
G TP53 tumor protein p53 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:21078376 PMID:23792339 PMID:24828139 RGD:8662307 NCBI chr16:7,047,686...7,065,567
Ensembl chr16:7,045,146...7,066,223 		JBrowse link
G TP63 tumor protein p63 ISO protein:increased expression:prostate gland RGD PMID:20041964 RGD:11568648 NCBI chr15:83,861,489...84,126,675 JBrowse link
G TPI1 triosephosphate isomerase 1 ISO protein:decreased expression:retina RGD PMID:17465459 RGD:5147874 NCBI chr11:6,900,762...6,904,188
Ensembl chr11:6,900,787...6,906,787 		JBrowse link
G TREX2 three prime repair exonuclease 2 ISO RGD PMID:20973890 RGD:5490977 NCBI chr  X:127,878,891...127,882,019 JBrowse link
G TRPC1 transient receptor potential cation channel subfamily C member 1 ISO mRNA:decreased expression:kidney, liver RGD PMID:18184923 RGD:2301838 NCBI chr15:47,827,295...47,909,207
Ensembl chr15:47,827,247...47,909,202 		JBrowse link
G TSC2 TSC complex subunit 2 ISO protein:increased threonine phosphorylation:cortex of kidney RGD PMID:18599524 RGD:8657153 NCBI chr 5:1,946,534...1,985,168
Ensembl chr 5:1,946,927...1,987,682 		JBrowse link
G TWNK twinkle mtDNA helicase ISO mRNA,protein:decreased expression:retina,mitochondrion: RGD PMID:22229649 PMID:22743328 RGD:8694093 RGD:8694187 NCBI chr 9:94,006,183...94,012,783
Ensembl chr 9:94,006,188...94,013,164 		JBrowse link
G TXN thioredoxin ISO mRNA:altered expression:myocardium (rat) RGD PMID:20571744 RGD:5133714 NCBI chr12:29,296,166...29,308,979 JBrowse link
G TXN2 thioredoxin 2 ISO mRNA:increased expression:glomerulus
mRNA:altered expression:myocardium (rat)		 RGD PMID:15039483 PMID:20571744 RGD:2306161 RGD:5133714 NCBI chr19:19,168,693...19,185,898
Ensembl chr19:19,169,286...19,185,735 		JBrowse link
G TXNIP thioredoxin interacting protein ISO protein:increased expression:kidney RGD PMID:17675577 RGD:1642749 NCBI chr20:12,756,145...12,759,853
Ensembl chr20:12,756,053...12,761,177 		JBrowse link
G TXNRD1 thioredoxin reductase 1 ISO mRNA:altered expression:myocardium (rat) RGD PMID:20571744 RGD:5133714 NCBI chr11:99,375,740...99,559,929
Ensembl chr11:99,490,597...99,560,267 		JBrowse link
G TXNRD2 thioredoxin reductase 2 ISO mRNA:altered expression:myocardium (rat) RGD PMID:20571744 RGD:5133714 NCBI chr19:5,803,178...5,868,224
Ensembl chr19:5,813,099...5,866,674 		JBrowse link
G UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 ISO mRNA:increased expression:kidney (mouse) RGD PMID:12171997 RGD:11352735 NCBI chr 6:17,040,127...17,043,569
Ensembl chr 6:17,040,064...17,045,737 		JBrowse link
G UCHL5 ubiquitin C-terminal hydrolase L5 ISO RGD PMID:23500140 RGD:9588239 NCBI chr25:36,362,340...36,415,550
Ensembl chr25:36,364,027...36,414,762 		JBrowse link
G UCK2 uridine-cytidine kinase 2 ISO protein:decreased activity:heart, skeletal muscle RGD PMID:221781 RGD:2317214 NCBI chr25:62,974,515...63,059,436
Ensembl chr25:62,974,257...63,059,414 		JBrowse link
G UCP2 uncoupling protein 2 ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:kidney		 CTD
RGD		 PMID:14563825 PMID:16123366 PMID:19227473 RGD:2313501 NCBI chr 1:65,238,311...65,246,841
Ensembl chr 1:65,235,775...65,246,450 		JBrowse link
G UCP3 uncoupling protein 3 susceptibility ISO mRNA:increased expression:skeletal muscle RGD PMID:10868941 PMID:12079841 RGD:2313520 RGD:2313524 NCBI chr 1:65,269,611...65,279,079
Ensembl chr 1:65,269,607...65,278,807 		JBrowse link
G UMOD uromodulin ISO protein:increased expression:urine RGD PMID:10925066 RGD:2324705 NCBI chr 5:18,620,927...18,641,312
Ensembl chr 5:18,619,895...18,638,719 		JBrowse link
G UMPS uridine monophosphate synthetase ISO protein:decreased activity:liver (rat)
protein:decreased activity:mammary gland (rat)		 RGD PMID:1476792 PMID:3907307 RGD:5132278 RGD:5132591 NCBI chr22:56,081,897...56,097,164
Ensembl chr22:56,082,103...56,097,105 		JBrowse link
G UPRT uracil phosphoribosyltransferase homolog ISO protein:decreased activity:mammary gland (rat) RGD PMID:1476792 RGD:5132591 NCBI chr  X:64,815,163...64,846,198
Ensembl chr  X:64,815,183...64,849,547 		JBrowse link
G UTS2R urotensin 2 receptor ISO RGD PMID:16267137 RGD:2306839 NCBI chr16:74,284,472...74,291,074
Ensembl chr16:74,288,333...74,289,502 		JBrowse link
G VCAM1 vascular cell adhesion molecule 1 ISO mRNA:increased expression:aorta
mRNA, protein:increased expression:kidney		 RGD PMID:18093596 PMID:18983856 RGD:2306988 RGD:2312764 NCBI chr20:32,616,425...32,635,903
Ensembl chr20:32,615,333...32,635,862 		JBrowse link
G VDAC1 voltage dependent anion channel 1 ISO protein:increased expression:kidney RGD PMID:19634143 RGD:10003054 NCBI chr23:36,783,670...36,817,071 JBrowse link
G VEGFA vascular endothelial growth factor A ISO mRNA:decreased expression:skeletal muscle
mRNA:decreased expression:heart
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:16741021 PMID:16816123 PMID:19934008 PMID:22191573 RGD:2313724 RGD:2313725 RGD:7421582 NCBI chr17:28,377,959...28,394,508 JBrowse link
G VEGFB vascular endothelial growth factor B ISO mRNA:decreased expression:skeletal muscle RGD PMID:16816123 RGD:2313725 NCBI chr 1:9,997,820...10,001,518
Ensembl chr 1:9,997,665...10,001,429 		JBrowse link
G VIP vasoactive intestinal peptide ISO RGD PMID:21129425 RGD:5685622 NCBI chr13:80,217,602...80,228,320
Ensembl chr13:80,218,572...80,228,278 		JBrowse link
G VIPR1 vasoactive intestinal peptide receptor 1 ISO RGD PMID:21129425 RGD:5685622 NCBI chr22:3,950,129...3,984,849
Ensembl chr22:3,950,193...3,984,948 		JBrowse link
G VLDLR very low density lipoprotein receptor ISO protein:decreased expression:heart, skeletal muscle RGD PMID:15878964 RGD:1625575 NCBI chr12:76,900,551...76,933,601
Ensembl chr12:76,899,189...76,933,584 		JBrowse link
G VWF von Willebrand factor ISO protein:increased expression:plasma RGD PMID:17546272 RGD:1625712 NCBI chr11:5,994,499...6,176,949
Ensembl chr11:5,994,039...6,162,260 		JBrowse link
G WDR35 WD repeat domain 35 ISO mRNA:increased expression:kidney (rat) RGD PMID:20224876 RGD:11553923 NCBI chr14:87,732,034...87,801,687
Ensembl chr14:87,732,049...87,801,852 		JBrowse link
G XDH xanthine dehydrogenase ISO protein:increased expression:brain, heart, kidney RGD PMID:14532905 RGD:1304441 NCBI chr14:76,084,693...76,162,840
Ensembl chr14:76,085,368...76,163,936 		JBrowse link
G YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta ISO CTD Direct Evidence: therapeutic CTD PMID:18342293 NCBI chr19:14,825,963...14,839,668
Ensembl chr19:14,826,135...14,840,325 		JBrowse link
Term paths to the root
Path 1
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  disease 15416
    Animal Diseases 1320
      Animal Disease Models 1280
        Experimental Diabetes Mellitus 574
Path 2
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  disease 15416
    Developmental Disease 13512
      Congenital, Hereditary, and Neonatal Diseases and Abnormalities 12674
        genetic disease 12376
          inherited metabolic disorder 5857
            carbohydrate metabolic disorder 2806
              glucose metabolism disease 0
                diabetes mellitus 1338
                  Experimental Diabetes Mellitus 574
paths to the root