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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Experimental Diabetes Mellitus
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Accession:DOID:9005643 term browser browse the term
Definition:Diabetes mellitus induced experimentally by administration of various diabetogenic agents or by PANCREATECTOMY.
Synonyms:exact_synonym: Alloxan Diabetes;   Experimental Diabetes Mellitus;   Streptozocin Diabete;   streptozocin diabetes;   streptozotocin diabetes
 primary_id: MESH:D003921
For additional species annotation, visit the Alliance of Genome Resources.


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Experimental Diabetes Mellitus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aacs acetoacetyl-CoA synthetase IDA protein:decreased activity:liver RGD PMID:12034369 RGD:2301022 NCBI chr12:36,512,393...36,555,694
Ensembl chr12:36,512,393...36,555,694
JBrowse link
G Aanat aralkylamine N-acetyltransferase IEP RGD PMID:18624957 RGD:2301030 NCBI chr10:105,568,091...105,572,407
Ensembl chr10:105,568,091...105,572,403
JBrowse link
G Abat 4-aminobutyrate aminotransferase IDA RGD PMID:9846053 RGD:1598518 NCBI chr10:7,093,406...7,200,439
Ensembl chr10:7,093,405...7,200,499
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A disease_progression
treatment
IAGP
IEP
IDA
protein: decreased expression
mRNA:increased expression:brain
mRNA:increased expression:ileum, intestinal mucosa (rat)
RGD PMID:17074306, PMID:17664251, PMID:26460146, PMID:21685928 RGD:1598559, RGD:2312730, RGD:11041112, RGD:8657121 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B disease_progression IDA
IEP
mRNA:increased expression:brain
mRNA:increased expression:ileum, intestinal mucosa (rat)
RGD PMID:17074306, PMID:17664251, PMID:26460146 RGD:1598559, RGD:2312730, RGD:11041112 NCBI chr 4:22,225,123...22,307,577
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 IDA RGD PMID:12055592 RGD:1598588 NCBI chr 4:22,133,984...22,192,687
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 IEP protein: increased expression
mRNA:decreased expression:liver
mRNA: increased expression: brain
RGD PMID:19356064, PMID:20487213, PMID:17664251 RGD:2312728, RGD:11541075, RGD:2312730 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 IEP mRNA:increased expression:liver RGD PMID:20487213 RGD:11541075 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Abcc9 ATP binding cassette subfamily C member 9 IEP mRNA, protein:decreased expression:heart RGD PMID:22257425 RGD:12792003 NCBI chr 4:176,806,098...176,928,540
Ensembl chr 4:176,805,431...176,922,424
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 IEP protein:decreased expression:cerebral cortex RGD PMID:17915193 RGD:2315584 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 IEP RGD PMID:14618236 RGD:1558629 NCBI chr 6:7,935,771...7,961,207
Ensembl chr 6:7,935,771...7,961,207
JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 IEP RGD PMID:14618236 RGD:1558629 NCBI chr 6:7,961,413...7,980,708
Ensembl chr 6:7,961,413...7,980,708
JBrowse link
G Acaa1a acetyl-CoA acyltransferase 1A IEP mRNA:increased expression:heart RGD PMID:17632588 RGD:2313044 NCBI chr 8:128,027,880...128,036,471
Ensembl chr 8:128,027,958...128,036,236
JBrowse link
G Acadvl acyl-CoA dehydrogenase, very long chain ISO protein:decreased expression:brain RGD PMID:25260493 RGD:10047114 NCBI chr10:56,619,321...56,624,468
Ensembl chr10:56,619,303...56,624,526
JBrowse link
G Ace angiotensin I converting enzyme IEP
ISO
protein:increased expression:kidney
CTD Direct Evidence: marker/mechanism
CTD PMID:22191573, PMID:18679036 RGD:2313799 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Ace2 angiotensin I converting enzyme 2 IEP protein:altered expression:kidney RGD PMID:18679036 RGD:2313799 NCBI chr  X:32,050,734...32,095,860
Ensembl chr  X:32,049,931...32,096,016
JBrowse link
G Ache acetylcholinesterase IEP
IDA
protein:altered activity
protein:increased expression:blood
RGD PMID:1385785, PMID:19374834, PMID:19296211, PMID:19303406 RGD:2312437, RGD:2312424, RGD:2312432, RGD:2312430 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Acmsd aminocarboxymuconate semialdehyde decarboxylase treatment IDA
IEP
RGD PMID:12042425, PMID:19169727 RGD:13831125, RGD:13831126 NCBI chr13:44,424,689...44,468,734
Ensembl chr13:44,424,689...44,468,734
JBrowse link
G Acot1 acyl-CoA thioesterase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14563825 NCBI chr 6:107,485,088...107,493,082
Ensembl chr 6:107,485,249...107,493,798
JBrowse link
G Acot2 acyl-CoA thioesterase 2 IEP protein:increased expression:heart, mitochondrion (rat) RGD PMID:17438340 RGD:2315861 NCBI chr 6:107,460,596...107,468,324
Ensembl chr 6:107,460,668...107,467,487
JBrowse link
G Acox1 acyl-CoA oxidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14563825 NCBI chr10:104,724,534...104,748,003
Ensembl chr10:104,722,958...104,748,050
JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant IEP protein:increased activity:femoral bone (rat) RGD PMID:19699734 RGD:2315882 NCBI chr 8:23,142,733...23,149,067
Ensembl chr 8:23,142,734...23,148,396
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:9452481 NCBI chr16:48,937,456...49,003,898
Ensembl chr16:48,937,456...49,003,246
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 IEP RGD PMID:21136146 RGD:13831298 NCBI chr 9:84,569,601...84,593,565
Ensembl chr 9:84,569,597...84,593,565
JBrowse link
G Acsl6 acyl-CoA synthetase long-chain family member 6 IEP mRNA:decreased expression:heart RGD PMID:16428347 RGD:1599808 NCBI chr10:39,654,771...39,717,592
Ensembl chr10:39,655,455...39,719,312
JBrowse link
G Ada adenosine deaminase IEP
ISO
protein:increased expression:platelet RGD PMID:19166862, PMID:9784839 RGD:2313538, RGD:2313540 NCBI chr 3:160,115,840...160,139,947
Ensembl chr 3:160,115,842...160,139,947
JBrowse link
G Adcyap1 adenylate cyclase activating polypeptide 1 IEP protein:increased expression:pancreas, hypothalamus RGD PMID:9864055 RGD:2325314 NCBI chr 9:121,705,897...121,725,736
Ensembl chr 9:121,706,979...121,725,716
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing IEP
ISO
mRNA, protein:decreased expression:adipose tissue, serum
protein:increased expression:retina
RGD PMID:16201273, PMID:23174569 RGD:1599146, RGD:8694416 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Adipor2 adiponectin receptor 2 no_association IDA
ISO
RGD PMID:17884446, PMID:19220660, PMID:18222103 RGD:2312495, RGD:2312478, RGD:2312488 NCBI chr 4:151,412,135...151,480,108
Ensembl chr 4:151,414,684...151,428,894
JBrowse link
G Adk adenosine kinase IEP protein:decreased expression:spleen, lymphocyte RGD PMID:12729803 RGD:2313360 NCBI chr15:3,033,535...3,435,888
Ensembl chr15:3,033,495...3,435,888
JBrowse link
G Adm adrenomedullin IEP protein:increased expression:pigmented epithelial cell, retina RGD PMID:16955796 RGD:1625296 NCBI chr 1:175,443,189...175,447,260
Ensembl chr 1:175,445,088...175,447,259
JBrowse link
G Adora1 adenosine A1 receptor treatment IDA
ISO
IEP
associated with hypertension
protein:decreased expression:hippocampus
RGD PMID:11593763, PMID:9597368, PMID:19276628, PMID:16256246 RGD:2313808, RGD:1625365, RGD:2313804, RGD:2313805 NCBI chr13:51,042,111...51,076,913
Ensembl chr13:51,042,248...51,076,852
JBrowse link
G Adora2a adenosine A2a receptor IEP protein:increased expression:hippocampus RGD PMID:16256246 RGD:2313805 NCBI chr20:14,265,251...14,282,873
Ensembl chr20:14,265,252...14,282,873
JBrowse link
G Adra1a adrenoceptor alpha 1A IEP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:19133277, PMID:17054657 RGD:1625775 NCBI chr15:43,296,997...43,398,314
Ensembl chr15:43,298,794...43,392,451
JBrowse link
G Adrb1 adrenoceptor beta 1 IEP protein:decreased expression:left ventricle muscular part RGD PMID:21054861 RGD:5129115 NCBI chr 1:277,537,585...277,538,985
Ensembl chr 1:277,537,585...277,538,985
JBrowse link
G Adrb3 adrenoceptor beta 3 IEP
ISO
protein:increased expression:left ventricle muscular part
CTD Direct Evidence: marker/mechanism
CTD PMID:17622774, PMID:21054861 RGD:5129115 NCBI chr16:69,003,541...69,006,632
Ensembl chr16:69,003,868...69,006,632
JBrowse link
G Adsl adenylosuccinate lyase IEP protein:increased activity:heart (rat) RGD PMID:3360219 RGD:1598762 NCBI chr 7:122,157,201...122,192,328
Ensembl chr 7:122,157,201...122,192,328
JBrowse link
G Adssl1 adenylosuccinate synthase like 1 IEP protein:increased activity:heart (rat) RGD PMID:3360219 RGD:1598762 NCBI chr 6:137,184,818...137,206,694
Ensembl chr 6:137,184,820...137,206,693
JBrowse link
G Ager advanced glycosylation end product-specific receptor treatment IEP
IDA
ISO
protein:increased expression:lacrimal gland
mRNA:increased expression:renal cortex (mouse)
RGD PMID:16283249, PMID:22476978, PMID:21458563, PMID:20801062 RGD:1625335, RGD:7245558, RGD:7244188, RGD:7243964 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Agt angiotensinogen ISO CTD Direct Evidence: marker/mechanism CTD PMID:15831366 PMID:17177138 PMID:18829990 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Agtr2 angiotensin II receptor, type 2 IEP mRNA, protein:decreased expression:kidney RGD PMID:12172324 RGD:6903861 NCBI chr  X:119,389,480...119,393,845
Ensembl chr  X:119,390,013...119,393,842
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23499715 NCBI chr  X:135,304,063...135,343,062
Ensembl chr  X:135,304,066...135,343,087
JBrowse link
G Aire autoimmune regulator susceptibility ISO RGD PMID:18399912 RGD:2306853 NCBI chr20:11,365,630...11,380,636
Ensembl chr20:11,365,697...11,380,631
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B IEP mRNA:increased expression:kidney (rat) RGD PMID:8204669 RGD:8548781 NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956
JBrowse link
G Akt1 AKT serine/threonine kinase 1 IDA
IEP
protein:decreased serine phosphorylation:cornea
protein:increased serine phosphorylation:cortex of kidney
RGD PMID:21330660, PMID:18599524 RGD:5131482, RGD:8657153 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Alad aminolevulinate dehydratase susceptibility
treatment
IEP
IDA
ISO
protein:decreased activity:liver, kidney (rat)
protein:decreased activity:liver, erythrocyte (rat)
protein:decreased activity:blood, liver
RGD PMID:19043199, PMID:10224671, PMID:18668330, PMID:21864646, PMID:24947461, PMID:7728901 RGD:4144150, RGD:15039405, RGD:12904704, RGD:12904702, RGD:12904692, RGD:12904683 NCBI chr 5:78,368,867...78,379,206
Ensembl chr 5:78,368,867...78,379,346
JBrowse link
G Alas1 5'-aminolevulinate synthase 1 IEP protein:decreased activity:liver (rat) RGD PMID:6688350 RGD:4144808 NCBI chr 8:114,927,704...114,941,038
Ensembl chr 8:114,927,722...114,940,177
JBrowse link
G Aldob aldolase, fructose-bisphosphate B IEP mRNA:reduced expression:liver, small intestine (rat) RGD PMID:2984252 RGD:2313437 NCBI chr 5:64,805,772...64,818,813
Ensembl chr 5:64,805,773...64,818,824
JBrowse link
G Andpro androgen regulated protein IEP protein:decreased expression:corpus cavernosum penis (rat) RGD PMID:20007950 RGD:14696816 NCBI chr 3:143,893,005...143,899,609
Ensembl chr 3:143,893,006...143,899,370
JBrowse link
G Angpt1 angiopoietin 1 IEP protein:increased expression:retina RGD PMID:15047628, PMID:17294737 RGD:2313817, RGD:1626163 NCBI chr 7:81,338,327...81,592,459
Ensembl chr 7:81,342,280...81,592,206
JBrowse link
G Angpt2 angiopoietin 2 IEP protein:increased expression:retina RGD PMID:15047628 RGD:2313817 NCBI chr16:75,966,480...76,016,147
Ensembl chr16:75,966,352...76,016,195
JBrowse link
G Angptl3 angiopoietin-like 3 ISO protein:increased expression:liver RGD PMID:15094378 RGD:2314234 NCBI chr 5:117,698,590...117,706,729
Ensembl chr 5:117,698,764...117,705,808
JBrowse link
G Anxa1 annexin A1 IEP protein:increased glycation:respiratory system blood vessel endothelium RGD PMID:11423489 RGD:2306888 NCBI chr 1:237,893,983...237,910,002
Ensembl chr 1:237,893,966...237,910,012
JBrowse link
G Anxa2 annexin A2 IEP protein:increased glycation:respiratory system blood vessel endothelium RGD PMID:11423489 RGD:2306888 NCBI chr 8:75,687,134...75,723,589
Ensembl chr 8:75,687,100...75,723,594
JBrowse link
G Aoc1 amine oxidase, copper containing 1 IEP RGD PMID:1632778 RGD:2312809 NCBI chr 4:78,496,043...78,515,582
Ensembl chr 4:78,496,043...78,515,584
JBrowse link
G Aoc3 amine oxidase, copper containing 3 ISO
IEP
IMP
CTD Direct Evidence: marker/mechanism
protein:increased expression:kidney, serum
CTD PMID:14977883, PMID:12606817, PMID:2218072, PMID:19635478 RGD:2313824, RGD:2313828, RGD:2313819 NCBI chr10:89,251,370...89,259,313
Ensembl chr10:89,251,370...89,259,313
JBrowse link
G Apoa1 apolipoprotein A1 treatment IDA RGD PMID:17488882 RGD:7241577 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Apob apolipoprotein B IEP RGD PMID:17292734 RGD:1642185 NCBI chr 6:33,176,826...33,216,381
Ensembl chr 6:33,176,778...33,224,997
JBrowse link
G Apoe apolipoprotein E IEP protein:decreased expression:plasma (rat) RGD PMID:16947119 RGD:1599198 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Apom apolipoprotein M ISO protein:decreased secretion:plasma RGD PMID:16516154 RGD:2314249 NCBI chr20:5,120,473...5,123,073
Ensembl chr20:5,120,474...5,123,073
JBrowse link
G Aprt adenine phosphoribosyl transferase IEP protein:decreased activity:mammary gland (rat) RGD PMID:2451510 RGD:1599204 NCBI chr19:55,387,288...55,389,256
Ensembl chr19:55,387,288...55,389,256
JBrowse link
G Aqp1 aquaporin 1 IEP protein:increased expression:retina RGD PMID:19596320 RGD:2316078 NCBI chr 4:85,551,503...85,563,683
Ensembl chr 4:85,551,502...85,569,360
JBrowse link
G Aqp2 aquaporin 2 IEP
ISO
protein:increased expression:Kidney Medulla
protein:decreased expression:kidney collecting duct
RGD PMID:11380083, PMID:15705184 RGD:2314347, RGD:2314326 NCBI chr 7:141,237,802...141,242,837
Ensembl chr 7:141,237,768...141,245,165
JBrowse link
G Aqp4 aquaporin 4 IEP mRNA,protein:increased expression:retina: RGD PMID:22449442 RGD:8695996 NCBI chr18:6,766,009...6,782,757
Ensembl chr18:6,765,945...6,782,996
JBrowse link
G Ar androgen receptor ISO
IEP
protein:decreased expression:pancreatic B cell
mRNA, protein:decreased expression:epididymis, prostate gland, testis
RGD PMID:18543106, PMID:16398356 RGD:2306772, RGD:2306774 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Arg1 arginase 1 IEP protein:increased expression:aorta, liver (rat) RGD PMID:17967788 RGD:4142848 NCBI chr 1:21,525,421...21,537,872
Ensembl chr 1:21,525,421...21,537,863
JBrowse link
G Arg2 arginase 2 IEP protein:increased activity:kidney (rat) RGD PMID:12841630 RGD:4143269 NCBI chr 6:102,311,097...102,338,406
Ensembl chr 6:102,311,116...102,338,520
JBrowse link
G Arntl aryl hydrocarbon receptor nuclear translocator-like IEP RGD PMID:18624957 RGD:2301030 NCBI chr 1:178,039,002...178,137,469
Ensembl chr 1:178,039,063...178,137,465
JBrowse link
G Aspa aspartoacylase ISO protein:increased expression:duodenum, brain RGD PMID:16707098 RGD:1601247 NCBI chr10:59,839,693...59,888,244
Ensembl chr10:59,839,852...59,892,960
JBrowse link
G Ass1 argininosuccinate synthase 1 IEP mRNA, protein:increased expression:aorta (rat) RGD PMID:11384198 RGD:1599310 NCBI chr 3:10,327,411...10,375,847
Ensembl chr 3:10,327,414...10,375,826
JBrowse link
G Atf3 activating transcription factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16123366 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Atg7 autophagy related 7 treatment ISO
IEP
protein:decreased expression:myocardium RGD PMID:24874076, PMID:24993523 RGD:11557993, RGD:11557996 NCBI chr 4:146,570,113...146,777,093
Ensembl chr 4:146,598,413...146,777,124
JBrowse link
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 IEP RGD PMID:28483572 RGD:12910731 NCBI chr 1:197,855,912...197,875,038 JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 IDA
IEP
ISO
protein:increased carbonylation:heart
CTD Direct Evidence: marker/mechanism
CTD PMID:16123366, PMID:21300842, PMID:20122173, PMID:28483572 RGD:6904139, RGD:13782130, RGD:12910731 NCBI chr12:39,553,903...39,603,326
Ensembl chr12:39,553,903...39,603,326
JBrowse link
G Atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 ISO
IEP
CTD Direct Evidence: marker/mechanism CTD PMID:16123366, PMID:20122173 RGD:13782130 NCBI chr10:59,528,849...59,560,440
Ensembl chr10:59,529,785...59,560,433
JBrowse link
G Atp4b ATPase H+/K+ transporting subunit beta IEP RGD PMID:20237950 RGD:14696743 NCBI chr16:81,136,218...81,145,131
Ensembl chr16:81,136,218...81,145,131
JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha IEP protein:decreased expression:cerebral cortex, mitochondrion (rat) RGD PMID:28526935 RGD:13703047 NCBI chr18:74,156,553...74,164,490
Ensembl chr18:74,156,553...74,164,495
JBrowse link
G Atp5f1b ATP synthase F1 subunit beta IEP associated with polycystic ovary syndrome;mRNA, protein:decreased expression:pancreas (rat) RGD PMID:28397049 RGD:13703107 NCBI chr 7:2,504,708...2,511,748
Ensembl chr 7:2,504,695...2,511,749
JBrowse link
G Atp5pd ATP synthase peripheral stalk subunit d IEP protein:decreased expression:retina (rat) RGD PMID:17465459 RGD:5147874 NCBI chr10:103,967,340...103,972,552
Ensembl chr10:103,967,312...103,972,668
JBrowse link
G Atp5pf ATP synthase peripheral stalk subunit F6 treatment IEP RGD PMID:28731155 RGD:13800891 NCBI chr11:24,286,806...24,294,419
Ensembl chr11:24,286,787...24,294,179
JBrowse link
G Avp arginine vasopressin ISO mRNA:increased expression:hypothalamus RGD PMID:18420743 RGD:2301919 NCBI chr 3:123,117,482...123,119,460
Ensembl chr 3:123,117,492...123,119,460
JBrowse link
G Bad BCL2-associated agonist of cell death IDA protein:increased expression, decreased phosphorylation, altered activity:testis
protein:decreased serine phosphorylation:cornea
RGD PMID:17870134, PMID:21330660 RGD:2292685, RGD:5131482 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bax BCL2 associated X, apoptosis regulator treatment IEP
ISO
protein:increased expression:retina
CTD Direct Evidence: marker/mechanism
CTD PMID:23090186, PMID:18991018, PMID:23267840 RGD:2311240, RGD:10054099 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bche butyrylcholinesterase IDA protein:decreased expression:retina RGD PMID:11478742, PMID:12379509, PMID:16187484 RGD:2306783, RGD:2306781, RGD:1599458 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395
JBrowse link
G Bckdha branched chain keto acid dehydrogenase E1 subunit alpha IEP protein:increased expression:liver RGD PMID:9460082 RGD:1599467 NCBI chr 1:82,423,291...82,452,094
Ensembl chr 1:82,423,277...82,452,281
JBrowse link
G Bckdhb branched chain keto acid dehydrogenase E1 subunit beta IEP Protein:increased expression:liver; RGD PMID:9460082 RGD:1599467 NCBI chr 8:91,464,229...91,656,134
Ensembl chr 8:91,464,229...91,656,134
JBrowse link
G Bcl2 BCL2, apoptosis regulator IEP
ISO
protein:increased expression:retina
CTD Direct Evidence: marker/mechanism
mRNA:decreased expression:embryo
CTD PMID:16959961 PMID:23090186, PMID:18991018, PMID:15649569 RGD:2311240, RGD:1599491 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 IDA
ISO
protein:decreased expression, altered activity:testis
CTD Direct Evidence: marker/mechanism
CTD PMID:16959961, PMID:17870134 RGD:2292685 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bdh1 3-hydroxybutyrate dehydrogenase 1 IEP protein:decreased activity:heart, mitochondrion (rat) RGD PMID:3548709 RGD:2326100 NCBI chr11:72,577,547...72,619,435
Ensembl chr11:72,578,533...72,614,176
JBrowse link
G Bdkrb1 bradykinin receptor B1 IEP
ISO
IDA
mRNA:increased expression:heart
CTD Direct Evidence: marker/mechanism
CTD PMID:21430409, PMID:12489796, PMID:20092893, PMID:12522068 RGD:704379, RGD:7241569, RGD:704380 NCBI chr 6:129,437,423...129,441,553
Ensembl chr 6:129,438,158...129,440,574
JBrowse link
G Bdkrb2 bradykinin receptor B2 IEP protein:increased expression:hindbrain, spinal cord
mRNA:increased expression:heart
RGD PMID:16138314, PMID:12489796 RGD:4890452, RGD:704379 NCBI chr 6:129,399,468...129,429,676
Ensembl chr 6:129,399,468...129,429,676
JBrowse link
G Bdnf brain-derived neurotrophic factor treatment IEP RGD PMID:24857910 RGD:10059399 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Becn1 beclin 1 treatment IEP RGD PMID:24993523 RGD:11557996 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Bglap bone gamma-carboxyglutamate protein IEP protein:reduced expression:serum (rat) RGD PMID:19494718 RGD:2316184 NCBI chr 2:187,741,770...187,748,445
Ensembl chr 2:187,741,770...187,742,747
JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 IEP protein:increased expression:lung RGD PMID:21521772 RGD:5135278 NCBI chr 9:66,568,074...66,683,019
Ensembl chr 9:66,568,074...66,676,494
JBrowse link
G Btc betacellulin ISO RGD PMID:14988244, PMID:19819964, PMID:18388935 RGD:1357906, RGD:2313774, RGD:2306965 NCBI chr14:18,231,854...18,270,621
Ensembl chr14:18,231,860...18,272,484
JBrowse link
G Cacng4 calcium voltage-gated channel auxiliary subunit gamma 4 IEP mRNA:decreased expression:sinoatrial node: RGD PMID:27096430 RGD:13524560 NCBI chr10:95,954,160...96,015,484
Ensembl chr10:95,951,234...96,015,499
JBrowse link
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase IEP protein:decreased activity:mammary gland (rat) RGD PMID:1476792 RGD:5132591 NCBI chr 6:26,657,507...26,680,459
Ensembl chr 6:26,657,780...26,680,284
JBrowse link
G Calca calcitonin-related polypeptide alpha IEP protein:increased expression:penis erectile tissue, seminal vesicle
protein:decreased expression:dorsal root ganglion, neuron
RGD PMID:19152794, PMID:17151309 RGD:2314033, RGD:2314035 NCBI chr 1:184,184,018...184,188,922
Ensembl chr 1:184,184,020...184,188,911
JBrowse link
G Cald1 caldesmon 1 IEP RGD PMID:10644879 RGD:2314036 NCBI chr 4:62,103,948...62,291,375
Ensembl chr 4:62,220,736...62,291,489
JBrowse link
G Capn10 calpain 10 IEP mRNA, protein:decreased expression:kidney cortex RGD PMID:22568896 RGD:7247732 NCBI chr 9:100,104,000...100,112,833
Ensembl chr 9:100,104,000...100,112,832
JBrowse link
G Carhsp1 calcium regulated heat stable protein 1 treatment IEP RGD PMID:19997081 RGD:39128203 NCBI chr10:7,041,510...7,055,107
Ensembl chr10:7,041,510...7,055,101
JBrowse link
G Casp1 caspase 1 IEP mRNA:increased expression:retina RGD PMID:18398369 RGD:2315888 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Casp3 caspase 3 treatment IEP
ISO
protein:increased activity:hypothalamus
CTD Direct Evidence: marker/mechanism
CTD PMID:20654064, PMID:19094082, PMID:28843149 RGD:2311447, RGD:13782300 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp6 caspase 6 IDA protein:increased activity:heart left ventricle RGD PMID:15662549 RGD:2301316 NCBI chr 2:235,341,326...235,353,715
Ensembl chr 2:235,341,365...235,353,967
Ensembl chr 2:235,341,365...235,353,967
JBrowse link
G Casp8 caspase 8 treatment ISO
IEP
protein:increased expression, increased activity:pituitary gland
protein:increased activity, increased expression:pituitary gland, prolactin secreting cell
RGD PMID:17563067, PMID:28843149, PMID:19540304, PMID:15976052 RGD:2311429, RGD:13782300, RGD:2311427, RGD:2311319 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 IEP protein:increased activity, increased expression:pituitary gland RGD PMID:15976052 RGD:2311319 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Casq1 calsequestrin 1 IEP protein:increased activity:skeletal muscle tissue RGD PMID:11976916 RGD:2314137 NCBI chr13:90,592,676...90,602,365
Ensembl chr13:90,592,681...90,602,365
JBrowse link
G Casr calcium-sensing receptor IEP protein:increased expression:pancreas, liver, kidney (rat) RGD PMID:22844268 RGD:7205442 NCBI chr11:67,188,204...67,262,261
Ensembl chr11:67,188,630...67,258,771
JBrowse link
G Cat catalase IEP
ISO
CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:12123627 PMID:15855331 PMID:20709041, PMID:20376213 RGD:5130772 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cav1 caveolin 1 IEP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:18266981, PMID:25086377 RGD:10045572 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Cav3 caveolin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18266981 NCBI chr 4:144,382,945...144,398,919
Ensembl chr 4:144,382,945...144,398,917
JBrowse link
G Cbr1 carbonyl reductase 1 IEP protein:decreased expression:pancreas (rat) RGD PMID:18452227 RGD:2302233 NCBI chr11:33,813,041...33,815,418
Ensembl chr11:33,845,463...33,847,793
JBrowse link
G Cck cholecystokinin IDA RGD PMID:15536283 RGD:2313638 NCBI chr 8:130,120,525...130,127,515
Ensembl chr 8:130,120,523...130,127,392
JBrowse link
G Cckbr cholecystokinin B receptor IEP mRNA, protein:decreased expression:pancreas RGD PMID:15161757 RGD:1358452 NCBI chr 1:170,262,218...170,272,298
Ensembl chr 1:170,262,156...170,272,298
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 treatment IEP
IDA
protein:increased expression:gingiva
protein:increased expression:plasma
RGD PMID:17876613, PMID:16891764, PMID:18976114 RGD:2306992, RGD:8549535, RGD:2306984 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl20 C-C motif chemokine ligand 20 ISO CTD Direct Evidence: therapeutic CTD PMID:21340626 NCBI chr 9:88,918,359...88,921,017
Ensembl chr 9:88,918,433...88,921,001
JBrowse link
G Ccn2 cellular communication network factor 2 IEP mRNA, protein:increased expression:heart, myocardium (rat) RGD PMID:19820199 RGD:2314021 NCBI chr 1:21,851,657...21,854,773
Ensembl chr 1:21,851,660...21,854,773
JBrowse link
G Ccna2 cyclin A2 IEP RGD PMID:20031167 RGD:2316310 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214
JBrowse link
G Ccnb1 cyclin B1 IEP mRNA:decreased expression:liver (rat) RGD PMID:20031167 RGD:2316310 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Ccnd3 cyclin D3 IEP protein:increased expression:kidney, glomerulus RGD PMID:19276076 RGD:2316018 NCBI chr 9:15,404,816...15,410,905
Ensembl chr 9:15,404,822...15,410,943
JBrowse link
G Ccnt1 cyclin T1 IEP mRNA,protein:decreased expression:liver: RGD PMID:20828602 RGD:9698426 NCBI chr 7:140,215,052...140,245,958
Ensembl chr 7:140,219,551...140,245,723
JBrowse link
G Ccr5 C-C motif chemokine receptor 5 IEP protein:increased expression:retina RGD PMID:21575160 RGD:11533943 NCBI chr 8:133,192,398...133,215,599
Ensembl chr 8:133,197,032...133,215,614
JBrowse link
G Cd28 Cd28 molecule ISO RGD PMID:11160314 RGD:2307200 NCBI chr 9:67,546,408...67,573,858
Ensembl chr 9:67,546,408...67,571,871
JBrowse link
G Cd36 CD36 molecule treatment IEP mRNA:increased expression:multiple organs RGD PMID:16838191, PMID:23691525 RGD:2307214, RGD:11041145 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cd3e CD3e molecule ISO RGD PMID:16628253 RGD:2314179 NCBI chr 8:49,297,604...49,309,370
Ensembl chr 8:49,297,608...49,308,806
JBrowse link
G Cd40lg CD40 ligand treatment ISO
IEP
protein:increased expression:platelet (rat) RGD PMID:21831422, PMID:19237211 RGD:11352661, RGD:2312338 NCBI chr  X:159,703,703...159,714,886
Ensembl chr  X:159,703,578...159,716,562
JBrowse link
G Cd68 Cd68 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:20388520 NCBI chr10:56,268,726...56,270,605
Ensembl chr10:56,268,720...56,270,640
JBrowse link
G Cd80 Cd80 molecule ISO RGD PMID:11160314 RGD:2307200 NCBI chr11:64,815,201...64,855,293
Ensembl chr11:64,827,635...64,855,353
JBrowse link
G Cd86 CD86 molecule ISO RGD PMID:8993020 RGD:2313930 NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795
JBrowse link
G Cdk9 cyclin-dependent kinase 9 IEP mRNA,protein:decreased expression:liver: RGD PMID:20828602 RGD:9698426 NCBI chr 3:11,742,269...11,747,117
Ensembl chr 3:11,742,266...11,747,113
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A IEP protein:increased expression:testes: RGD PMID:24828139 RGD:8662307 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cel carboxyl ester lipase IEP protein:decreased expression:pancreas, RGD PMID:8446851 RGD:2313971 NCBI chr 3:7,134,021...7,141,522
Ensembl chr 3:7,134,021...7,141,522
JBrowse link
G Cfd complement factor D IEP protein:decreased expression:serum RGD PMID:8372111 RGD:1624344 NCBI chr 7:12,634,216...12,635,939
Ensembl chr 7:12,634,216...12,635,943
JBrowse link
G Cftr CF transmembrane conductance regulator severity ISO RGD PMID:16804061 RGD:2314614 NCBI chr 4:42,693,263...42,860,679
Ensembl chr 4:42,692,836...42,860,676
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18603373 NCBI chr 4:64,089,028...64,091,090
Ensembl chr 4:64,088,900...64,091,090
JBrowse link
G Clps colipase IEP RGD PMID:19577003 RGD:2314624 NCBI chr20:5,803,447...5,806,107
Ensembl chr20:5,803,383...5,806,097
JBrowse link
G Clu clusterin IEP protein:increased expression:retina
protein:increased expression:pancreatic islet
RGD PMID:12763621, PMID:23351716 RGD:9068392, RGD:9068411 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857
JBrowse link
G Cma1 chymase 1 IEP protein:increased expression:mesenteric artery, mast cell (rat) RGD PMID:15337505 RGD:5128799 NCBI chr15:34,601,037...34,603,819
Ensembl chr15:34,601,037...34,603,819
JBrowse link
G Cnr1 cannabinoid receptor 1 IEP protein:increased expression:hypothalamus, striatum RGD PMID:18401837 RGD:2314633 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056
JBrowse link
G Comt catechol-O-methyltransferase IDA protein:decreased expression:liver RGD PMID:12010186 RGD:2289789 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Cp ceruloplasmin IEP Protein:increased expression:plasma RGD PMID:16947119 RGD:1599198 NCBI chr 2:104,744,249...104,803,034
Ensembl chr 2:104,744,461...104,799,853
JBrowse link
G Cps1 carbamoyl-phosphate synthase 1 IEP protein:increased activity:liver (rat) RGD PMID:2882780 RGD:4144110 NCBI chr 9:74,113,437...74,236,274
Ensembl chr 9:74,124,016...74,236,274
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:16123366 NCBI chr 1:218,568,157...218,629,679
Ensembl chr 1:218,569,510...218,629,678
JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:14563825 NCBI chr 7:130,395,211...130,404,731
Ensembl chr 7:130,395,194...130,405,347
JBrowse link
G Crh corticotropin releasing hormone IEP mRNA:increased expression:paraventricular hypothalamic nucleus (rat) RGD PMID:9652969 RGD:5508166 NCBI chr 2:104,459,999...104,461,863
Ensembl chr 2:104,459,999...104,461,863
JBrowse link
G Crp C-reactive protein IDA
ISO
RGD PMID:21736771, PMID:21736794 RGD:6482316, RGD:6907422 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Crtc2 CREB regulated transcription coactivator 2 IMP RGD PMID:23595987 RGD:9685169 NCBI chr 2:189,615,928...189,625,646
Ensembl chr 2:189,615,948...189,626,051
JBrowse link
G Ctsb cathepsin B IEP protein:decreased activity:glomerulus (rat) RGD PMID:10393385 RGD:2315531 NCBI chr15:46,316,741...46,337,613
Ensembl chr15:46,316,741...46,337,612
JBrowse link
G Ctsc cathepsin C IEP RGD PMID:148980 RGD:1599652 NCBI chr 1:151,918,514...151,949,979
Ensembl chr 1:151,918,571...151,949,983
JBrowse link
G Ctsl cathepsin L IEP mRNA:increased expression:gastrocnemius muscle (rat) RGD PMID:14718385 RGD:1641826 NCBI chr17:1,873,105...1,879,266
Ensembl chr17:1,872,848...1,879,279
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 IEP
ISO
mRNA:increased expression:kidney
CTD Direct Evidence: marker/mechanism
CTD PMID:20388520, PMID:15153757 RGD:4891992 NCBI chr19:10,644,267...10,654,861
Ensembl chr19:10,644,244...10,653,800
JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 IEP mRNA:increased expression:kidney RGD PMID:15153757 RGD:4891992 NCBI chr 8:128,740,756...128,754,514
Ensembl chr 8:128,740,756...128,754,514
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 ISO mRNA:increased expression:pancreatic islet RGD PMID:17372021 RGD:2311360 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 IEP
ISO
protein:increased expression:retina RGD PMID:18201529, PMID:17878289 RGD:2306555, RGD:2306557 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Cyba cytochrome b-245 alpha chain IEP
ISO
mRNA, protein:increased expression:aorta
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:pancreas:
CTD PMID:11812764 PMID:12967931, PMID:20226688, PMID:23905384 RGD:2317852, RGD:11040693 NCBI chr19:55,249,634...55,257,824
Ensembl chr19:55,249,616...55,257,876
JBrowse link
G Cybb cytochrome b-245 beta chain IEP
ISO
mRNA:increased expression:aorta
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:cerebral cortex;associated with reperfusion injury
CTD PMID:19478208, PMID:11157681, PMID:15148062 RGD:1599691, RGD:1599683 NCBI chr  X:14,578,330...14,610,049
Ensembl chr  X:14,578,264...14,612,547
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 IEP mRNA:decreased expression:sciatic nerve (rat) RGD PMID:20826654 RGD:4145530 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 IEP mRNA:increased expression:kidney RGD PMID:18582458 RGD:2307289 NCBI chr 7:116,248,759...116,255,205
Ensembl chr 7:116,156,219...116,255,167
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 IEP protein:decreased expression:ovary, testis (rat) RGD PMID:20428845 RGD:4890359 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 IDA
ISO
protein:increased expression:liver, microsome (rat)
CTD Direct Evidence: marker/mechanism
CTD PMID:22342832, PMID:10711628 RGD:2307074 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 IDA RGD PMID:3295473 RGD:2307313 NCBI chr 7:70,333,150...70,340,006
Ensembl chr 7:70,335,061...70,340,005
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 IEP
ISO
protein:increased expression:liver
CTD Direct Evidence: marker/mechanism
CTD PMID:22342832, PMID:17015271 RGD:2301459 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 ISO mRNA:increased expression:liver
CTD Direct Evidence: marker/mechanism
CTD PMID:22342832, PMID:11465407 RGD:2315743 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 ISO
IEP
mRNA, protein:increased expression:kidney, liver RGD PMID:12700423, PMID:19406192 RGD:2313685, RGD:2313683 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Dbh dopamine beta-hydroxylase IEP mRNA, protein:increased expression:adrenal gland (rat) RGD PMID:16396986 RGD:5130724 NCBI chr 3:5,709,236...5,731,895
Ensembl chr 3:5,709,236...5,731,898
JBrowse link
G Dcn decorin IEP RGD PMID:15713786 RGD:2311414 NCBI chr 7:38,742,250...38,782,282
Ensembl chr 7:38,742,051...38,782,323
JBrowse link
G Defb1 defensin beta 1 IEP RGD PMID:16740310 RGD:2312491 NCBI chr16:75,294,385...75,309,127
Ensembl chr16:75,294,376...75,309,176
JBrowse link
G Dhodh dihydroorotate dehydrogenase (quinone) IEP protein:decreased activity:mammary gland (rat) RGD PMID:1476792, PMID:1723607 RGD:5132591, RGD:11040445 NCBI chr19:42,066,103...42,087,906
Ensembl chr19:42,066,351...42,082,012
JBrowse link
G Dpp4 dipeptidylpeptidase 4 ISO RGD PMID:19765579 RGD:2313699 NCBI chr 3:48,291,055...48,372,672
Ensembl chr 3:48,291,055...48,372,672
JBrowse link
G Drd1 dopamine receptor D1 treatment IEP
IDA
protein:decreased activity:striatum (rat) RGD PMID:1386820, PMID:20513244 RGD:2311600, RGD:7248621 NCBI chr17:11,099,736...11,104,352
Ensembl chr17:11,101,306...11,103,541
JBrowse link
G Drd2 dopamine receptor D2 IEP protein:altered activity:hypothalamus, pancreatic islet, brainstem (rat) RGD PMID:17174299 RGD:1624999 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Dusp1 dual specificity phosphatase 1 IEP mRNA, protein:decreased expression:ventricle myocardium
mRNA:increased expression:retina
RGD PMID:17647144, PMID:17063547 RGD:2298672, RGD:7771540 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G Ece1 endothelin converting enzyme 1 IEP mRNA:increased expression:thoracic aorta RGD PMID:23600389 RGD:7243858 NCBI chr 5:156,215,469...156,318,652
Ensembl chr 5:156,215,417...156,318,671
JBrowse link
G Edn1 endothelin 1 treatment IEP
ISO
IDA
mRNA:increased expression:heart, kidney, retina (rat)
CTD Direct Evidence: marker/mechanism
CTD PMID:12458661 PMID:12967931, PMID:18516100, PMID:18351623, PMID:18351623 RGD:2313282, RGD:2312288, RGD:2312288 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Ednra endothelin receptor type A IMP RGD PMID:20690982 RGD:4892336 NCBI chr19:33,928,356...33,991,703
Ensembl chr19:33,928,356...33,991,703
JBrowse link
G Eef2 eukaryotic translation elongation factor 2 treatment IEP protein:decreased expression:cardiac muscle: RGD PMID:7513958 RGD:10401649 NCBI chr 7:11,401,501...11,406,771
Ensembl chr 7:11,401,501...11,406,771
JBrowse link
G Egfr epidermal growth factor receptor IDA protein:decreased tyrosine phosphorylation:cornea RGD PMID:21330660 RGD:5131482 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Eln elastin IEP mRNA:increased expression:bladder: RGD PMID:18279932 RGD:9585725 NCBI chr12:24,978,478...25,021,864
Ensembl chr12:24,978,483...25,021,863
JBrowse link
G Eno2 enolase 2 IEP protein:increased expression:brain RGD PMID:15780189 RGD:2293753 NCBI chr 4:157,285,192...157,294,090
Ensembl chr 4:157,285,179...157,294,047
JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 IEP protein:decreased expression:retina: RGD PMID:22864860 RGD:9685437 NCBI chr 7:94,479,931...94,563,086
Ensembl chr 7:94,480,396...94,563,001
JBrowse link
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 IEP protein,mRNA:increased expression:glial cell, retina:
protein:enzyme activity:platelet
RGD PMID:18687327, PMID:17119848 RGD:9685473, RGD:9685486 NCBI chr 1:259,692,020...259,818,922
Ensembl chr 1:259,739,955...259,819,494
JBrowse link
G Ep300 E1A binding protein p300 treatment ISO
IDA
IMP
IEP
mRNA:increased expression:retina, kidney (mouse)
mRNA:increased expression:heart (rat)
RGD PMID:18351623, PMID:22228707, PMID:18413674, PMID:18657544 RGD:2312288, RGD:7296926, RGD:2312263, RGD:2312287 NCBI chr 7:122,818,194...122,889,055
Ensembl chr 7:122,818,975...122,861,296
JBrowse link
G Epo erythropoietin IEP mRNA:increased expression:Schwann cell: RGD PMID:24673486 RGD:11041670 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G Epor erythropoietin receptor IEP mRNA:increased expression:Schwann cell: RGD PMID:24673486 RGD:11041670 NCBI chr 8:22,969,737...22,974,468
Ensembl chr 8:22,969,745...22,974,321
JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit treatment IEP RGD PMID:22228707 RGD:7296926 NCBI chr 1:80,256,973...80,268,198
Ensembl chr 1:80,256,973...80,268,198
JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit treatment IEP RGD PMID:22228707 RGD:7296926 NCBI chr10:2,010,140...2,037,953
Ensembl chr10:2,010,648...2,037,891
JBrowse link
G Esr1 estrogen receptor 1 IEP protein:decreased expression:penis
protein:decreased expression:vagina,nucleus
RGD PMID:15596216, PMID:16734901 RGD:2306775, RGD:2314014 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esrra estrogen related receptor, alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:23090186 NCBI chr 1:222,168,729...222,178,842
Ensembl chr 1:222,168,730...222,178,725
JBrowse link
G Ets1 ETS proto-oncogene 1, transcription factor IEP protein:increased expression:retina RGD PMID:17622743 RGD:2313849 NCBI chr 8:33,756,634...33,879,625
Ensembl chr 8:33,816,386...33,879,625
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit IEP protein:increased expression:kidney RGD PMID:23508046 RGD:9587808 NCBI chr 4:77,284,404...77,347,011
Ensembl chr 4:77,284,404...77,347,011
JBrowse link
G F11r F11 receptor IEP RGD PMID:18506084 RGD:7488940 NCBI chr13:89,826,272...89,850,151
Ensembl chr13:89,826,254...89,850,612
JBrowse link
G F2 coagulation factor II ISO protein:increased expression:kidney RGD PMID:15990447 RGD:2313862 NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031
JBrowse link
G F3 coagulation factor III, tissue factor ISO protein:increased activity:kidney RGD PMID:15990447 RGD:2313862 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
JBrowse link
G F7 coagulation factor VII IDA
IEP
protein:decreased activity:plasma (rat) RGD PMID:11474472, PMID:16779662 RGD:2312396, RGD:2312313 NCBI chr16:81,824,610...81,834,923
Ensembl chr16:81,824,111...81,834,945
JBrowse link
G Fabp3 fatty acid binding protein 3 IEP mRNA, protein:decreased expression:aorta RGD PMID:7744030 RGD:2307330 NCBI chr 5:148,528,854...148,535,597
Ensembl chr 5:148,528,725...148,535,565
JBrowse link
G Fabp4 fatty acid binding protein 4 IEP protein:decreased expresssion:fat cell RGD PMID:9059981 RGD:1625411 NCBI chr 2:93,792,666...93,797,267
Ensembl chr 2:93,792,601...93,797,305
JBrowse link
G Fads1 fatty acid desaturase 1 IEP RGD PMID:16099631 RGD:1625413 NCBI chr 1:226,234,034...226,249,118
Ensembl chr 1:226,234,074...226,249,138
JBrowse link
G Fas Fas cell surface death receptor onset ISO
IEP
CTD Direct Evidence: marker/mechanism
protein:increased expression:heart ventricle
CTD PMID:16123366, PMID:20004692, PMID:19820199 RGD:2315698, RGD:2314021 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Faslg Fas ligand IEP protein:increased expression:heart ventricle RGD PMID:19820199 RGD:2314021 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fbn1 fibrillin 1 IEP protein:increased expression:renal glomerulus (rat) RGD PMID:16380460 RGD:7365080 NCBI chr 3:117,569,708...117,766,160
Ensembl chr 3:117,569,697...117,766,120
JBrowse link
G Fcgbpl1 Fc fragment of IgG binding protein-like 1 IEP RGD PMID:20973890 RGD:5490977 NCBI chr 1:85,058,541...85,096,492
Ensembl chr 1:85,058,548...85,096,346
JBrowse link
G Fga fibrinogen alpha chain IEP protein:increased expression:plasma (rat) RGD PMID:23086277 RGD:9684989 NCBI chr 2:181,997,562...182,013,726
Ensembl chr 2:182,006,242...182,013,763
JBrowse link
G Fgf2 fibroblast growth factor 2 IEP protein:increased expression:vitreous humor RGD PMID:12663474, PMID:10792180 RGD:2315880, RGD:8655613 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Fgf21 fibroblast growth factor 21 treatment IEP
ISO
protein:decreased expression:serum:
CTD Direct Evidence: therapeutic
CTD PMID:23499715, PMID:23262585, PMID:25359298, PMID:23262585 RGD:10401916, RGD:10401921, RGD:10401916 NCBI chr 1:101,595,579...101,596,822
Ensembl chr 1:101,595,579...101,596,822
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 IEP
ISO
mRNA:decreased expression:heart
mRNA:decreased expression:skeletal muscle
RGD PMID:16741021, PMID:16816123 RGD:2313724, RGD:2313725 NCBI chr12:9,033,993...9,205,886
Ensembl chr12:9,034,308...9,205,905
JBrowse link
G Fn1 fibronectin 1 treatment IEP protein:increased expression:kidney RGD PMID:22937115, PMID:22228707 RGD:7206838, RGD:7296926 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Foxa2 forkhead box A2 IEP mRNA:increased expression:kidney cortex RGD PMID:19433262 RGD:2312358 NCBI chr 3:142,383,084...142,387,493
Ensembl chr 3:142,383,278...142,387,481
JBrowse link
G Foxa3 forkhead box A3 IEP mRNA:increased expression:liver RGD PMID:11018767 RGD:2315085 NCBI chr 1:79,921,292...79,930,219
Ensembl chr 1:79,920,752...79,930,263
JBrowse link
G Foxo3 forkhead box O3 IEP
ISO
protein:increased phosphorylation, increased expression:glomerulus, cytoplasm:
CTD Direct Evidence: marker/mechanism
mRNA:decreased expression:liver:
CTD PMID:23090186 PMID:23792339, PMID:17082237, PMID:12683947, PMID:17082237 RGD:10402196, RGD:10402199, RGD:10402196 NCBI chr20:46,428,078...46,519,156
Ensembl chr20:46,428,124...46,519,144
JBrowse link
G Foxp3 forkhead box P3 treatment IEP mRNA,protein:increased expression: peripheral blood, spleen, lymphoid node RGD PMID:18328191, PMID:32341701 RGD:38599142, RGD:38599143 NCBI chr  X:15,753,175...15,768,648
Ensembl chr  X:15,753,175...15,768,522
JBrowse link
G Fuca1 alpha-L-fucosidase 1 ISO RGD PMID:3924473 RGD:2315947 NCBI chr 5:154,269,296...154,286,545
Ensembl chr 5:154,269,118...154,286,544
JBrowse link
G Furin furin (paired basic amino acid cleaving enzyme) disease_progression IEP protein:decreased expression:kidney RGD PMID:16541018 RGD:1582625 NCBI chr 1:142,185,092...142,198,167
Ensembl chr 1:142,185,094...142,197,182
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 treatment IEP protein:increased activity:liver, kidney RGD PMID:16176150, PMID:27366200 RGD:2315960, RGD:14695533 NCBI chr10:89,286,009...89,296,213
Ensembl chr10:89,285,855...89,296,213
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase treatment IEP protein:increased expression:lens
protein:decreased expression:liver
RGD PMID:16718375, PMID:25116122, PMID:19374864 RGD:2307345, RGD:10449121, RGD:2307337 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 IEP RGD PMID:2849069 RGD:2315971 NCBI chr20:1,955,344...1,984,907
Ensembl chr20:1,955,359...1,984,863
JBrowse link
G Gal galanin and GMAP prepropeptide ISO
IEP
protein:decreased expression:pancreatic islet RGD PMID:7505518, PMID:11489087 RGD:2313742, RGD:2313740 NCBI chr 1:218,653,059...218,657,922
Ensembl chr 1:218,652,917...218,657,925
JBrowse link
G Galp galanin-like peptide IMP
IEP
mRNA:increased expression:arcuate nucleus, pars posterior RGD PMID:16046316, PMID:15256810 RGD:2313737, RGD:2313739 NCBI chr 1:71,352,417...71,374,457
Ensembl chr 1:71,352,419...71,373,605
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase treatment IEP RGD PMID:27655796 RGD:13792671 NCBI chr 4:157,676,336...157,680,322
Ensembl chr 4:157,676,595...157,679,962
JBrowse link
G Gata4 GATA binding protein 4 IEP protein:increased serine phosphorylation:heart RGD PMID:22293779 RGD:7207042 NCBI chr15:46,386,703...46,458,679
Ensembl chr15:46,386,712...46,432,965
JBrowse link
G Gc GC, vitamin D binding protein IEP protein:decreased expression:serum RGD PMID:3838933 RGD:2315540 NCBI chr14:20,267,023...20,302,577
Ensembl chr14:20,266,891...20,302,581
JBrowse link
G Gcg glucagon treatment IEP RGD PMID:18996945 RGD:10402370 NCBI chr 3:48,442,635...48,451,650
Ensembl chr 3:48,442,635...48,451,650
JBrowse link
G Gck glucokinase IMP
ISO
protein:decreased activity:liver:reduced activity, energy of activation and affinity for glucose in streptozotocin diabetic rats
CTD Direct Evidence: marker/mechanism
CTD PMID:16123366, PMID:2132180 RGD:2301955 NCBI chr14:86,149,146...86,191,589
Ensembl chr14:86,148,928...86,190,659
JBrowse link
G Gcnt1 glucosaminyl (N-acetyl) transferase 1 IDA mRNA:increased expression:heart RGD PMID:7560067 RGD:632804 NCBI chr 1:236,547,729...236,585,037
Ensembl chr 1:236,580,034...236,585,035
JBrowse link
G Gfpt1 glutamine fructose-6-phosphate transaminase 1 IEP protein:decreased expression:epididymal fat pad, liver, skeletal muscle RGD PMID:7589852 RGD:2313355 NCBI chr 4:118,852,046...118,901,583
Ensembl chr 4:118,852,062...118,901,591
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 IEP protein:increased activity:serum RGD PMID:18291430 RGD:2315577 NCBI chr20:14,019,723...14,045,781
Ensembl chr20:14,019,723...14,025,068
JBrowse link
G Gh1 growth hormone 1 IDA
IEP
protein:decreased expression:serum, pituitary gland RGD PMID:2931155, PMID:19370419 RGD:2315682, RGD:2315655 NCBI chr10:94,486,204...94,488,181
Ensembl chr10:94,486,205...94,488,180
JBrowse link
G Ghr growth hormone receptor ISO
IEP
RGD PMID:12529387, PMID:7964296 RGD:2307365, RGD:11567222 NCBI chr 2:53,149,225...53,413,954
Ensembl chr 2:53,150,370...53,413,638
JBrowse link
G Ghrh growth hormone releasing hormone treatment IDA RGD PMID:22393012 RGD:10401241 NCBI chr 3:153,449,124...153,468,794
Ensembl chr 3:153,449,125...153,468,794
JBrowse link
G Ghrhr growth hormone releasing hormone receptor IEP RGD PMID:18285528 RGD:10401258 NCBI chr 4:85,587,321...85,602,389
Ensembl chr 4:85,588,595...85,601,666
JBrowse link
G Ghrl ghrelin and obestatin prepropeptide disease_progression ISO
IEP
protein:increased expression:plasma RGD PMID:18657539, PMID:23965296 RGD:2313750, RGD:12905048 NCBI chr 4:145,674,157...145,678,066
Ensembl chr 4:145,674,157...145,678,066
JBrowse link
G Ghsr growth hormone secretagogue receptor IEP mRNA:increased expression:Arcuate nucleus : RGD PMID:23965296 RGD:12905048 NCBI chr 2:113,065,953...113,071,265
Ensembl chr 2:113,066,885...113,070,261
JBrowse link
G Gip gastric inhibitory polypeptide IEP mRNA:increased expression:retina (rat) RGD PMID:12789546 RGD:2312548 NCBI chr10:83,835,080...83,848,399
Ensembl chr10:83,840,303...83,848,396
JBrowse link
G Gipr gastric inhibitory polypeptide receptor IEP mRNA:increased expression:retina (rat) RGD PMID:12789546 RGD:2312548 NCBI chr 1:80,063,047...80,073,223
Ensembl chr 1:80,063,049...80,073,223
JBrowse link
G Gja1 gap junction protein, alpha 1 treatment IEP
ISO
IDA
protein:increased expression:dermis
protein:decreased expression:retina, blood vessel
protein:altered expression:retina:
RGD PMID:22455314, PMID:20130277, PMID:22110070, PMID:20609064 RGD:7207269, RGD:8662383, RGD:7364887, RGD:7207415 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Gja5 gap junction protein, alpha 5 treatment IDA RGD PMID:20609064 RGD:7207415 NCBI chr 2:199,162,745...199,184,942
Ensembl chr 2:199,162,745...199,184,939
JBrowse link
G Gjb2 gap junction protein, beta 2 IEP mRNA,protein:decreased expression:retina: RGD PMID:22110070 RGD:7364887 NCBI chr15:37,377,313...37,394,494
Ensembl chr15:37,377,316...37,383,277
JBrowse link
G Gjb6 gap junction protein, beta 6 IEP RGD PMID:21567444 RGD:7364783 NCBI chr15:37,400,888...37,411,656
Ensembl chr15:37,400,889...37,410,848
JBrowse link
G Gjd3 gap junction protein, delta 3 IEP protein:decreased expression:retina: RGD PMID:23385797 RGD:7364769 NCBI chr10:86,888,982...86,891,915
Ensembl chr10:86,889,421...86,890,257
JBrowse link
G Glp1r glucagon-like peptide 1 receptor IDA RGD PMID:10580413 RGD:1624356 NCBI chr20:9,586,075...9,626,228
Ensembl chr20:9,586,075...9,626,228
JBrowse link
G Glrx glutaredoxin IEP protein:increase activity:retina: RGD PMID:17324929 RGD:9686046 NCBI chr 2:2,606,032...2,615,944
Ensembl chr 2:2,605,996...2,615,944
JBrowse link
G Gmps guanine monophosphate synthase IEP protein:increased activity:liver (rat) RGD PMID:3043317 RGD:5135485 NCBI chr 2:154,555,967...154,590,662
Ensembl chr 2:154,555,871...154,590,662
JBrowse link
G Gnat1 G protein subunit alpha transducin 1 IEP protein:decreased expression:retina RGD PMID:15939031 RGD:1600001 NCBI chr 8:116,433,302...116,438,038
Ensembl chr 8:116,433,302...116,438,038
JBrowse link
G Gnat3 G protein subunit alpha transducin 3 IEP mRNA, protein;increased expression:taste bud RGD PMID:18824257 RGD:2302147 NCBI chr 4:13,827,764...13,878,126
Ensembl chr 4:13,827,756...13,878,126
JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial ISO CTD Direct Evidence: marker/mechanism CTD PMID:9452481 NCBI chr 1:275,843,823...275,906,880
Ensembl chr 1:275,846,819...275,906,686
JBrowse link
G Gpd2 glycerol-3-phosphate dehydrogenase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16123366 NCBI chr 3:43,223,892...43,359,069
Ensembl chr 3:43,255,567...43,359,074
JBrowse link
G Gpx1 glutathione peroxidase 1 treatment IEP
ISO
protein:increased expression:liver
CTD Direct Evidence: marker/mechanism
protein:increased expression:glomerulus
CTD PMID:16123366, PMID:19229592, PMID:25744399, PMID:15039483, PMID:18387670 RGD:2306606, RGD:11353782, RGD:2306161, RGD:2306607 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gpx3 glutathione peroxidase 3 IEP
IDA
ISO
protein, mRNA:decreased expression:kidney (rat)
mRNA:increased expression:heart (mouse)
RGD PMID:12753302, PMID:12753302, PMID:16651743 RGD:2312629, RGD:2312629, RGD:2312631 NCBI chr10:40,247,436...40,255,423
Ensembl chr10:40,247,436...40,255,422
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B IEP mRNA, protein:increased expression:cerebellum (rat) RGD PMID:20056114 RGD:4107025 NCBI chr 4:169,541,620...170,000,216
Ensembl chr 4:169,560,387...169,999,873
JBrowse link
G Grk1 G protein-coupled receptor kinase 1 IEP protein:increased expression:retina RGD PMID:15939031 RGD:1600001 NCBI chr16:81,153,489...81,165,442
Ensembl chr16:81,153,489...81,165,442
JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha treatment IEP RGD PMID:8526919 RGD:10401824 NCBI chr 1:82,097,244...82,108,238
Ensembl chr 1:82,097,247...82,108,203
JBrowse link
G Gsr glutathione-disulfide reductase treatment IEP
ISO
protein:decreased activity:plasma:
CTD Direct Evidence: marker/mechanism
CTD PMID:20620209, PMID:20187988, PMID:25050809 RGD:7257587, RGD:10401889 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gsta4 glutathione S-transferase alpha 4 IEP protein:increased expression:pancreas, kidney, liver (rat) RGD PMID:14693714 RGD:5687773 NCBI chr 8:85,497,557...85,514,732
Ensembl chr 8:85,497,557...85,518,879
JBrowse link
G Guk1 guanylate kinase 1 IEP protein:decreased expression:retina (rat) RGD PMID:17465459 RGD:5147874 NCBI chr10:45,535,617...45,552,455
Ensembl chr10:45,535,627...45,543,897
JBrowse link
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) IDA RGD PMID:20923496 RGD:6784507 NCBI chr 5:166,994,683...167,030,441
Ensembl chr 5:166,998,881...167,030,441
JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase IEP RGD PMID:7050060 RGD:2302232 NCBI chr 2:236,353,445...236,395,067
Ensembl chr 2:236,353,445...236,395,067
JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha ISO protein:decreased expression:brain RGD PMID:25260493 RGD:10047114 NCBI chr 6:27,589,840...27,628,921
Ensembl chr 6:27,589,657...27,629,175
JBrowse link
G Hbb-bs hemoglobin, beta adult s chain IEP RGD PMID:20973890 RGD:5490977 NCBI chr 1:168,964,202...168,965,568
Ensembl chr 1:168,945,449...168,965,566
JBrowse link
G Hcn1 hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 IEP protein:increased expression:neuron: RGD PMID:19815055 RGD:9693680 NCBI chr 2:50,099,576...50,499,799
Ensembl chr 2:50,099,576...50,499,799
JBrowse link
G Hcn2 hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 IEP protein:increased expression:neuron: RGD PMID:19815055 RGD:9693680 NCBI chr 7:12,851,730...12,870,087
Ensembl chr 7:12,851,739...12,874,215
JBrowse link
G Hcn3 hyperpolarization-activated cyclic nucleotide-gated potassium channel 3 IEP protein:increased expression:neuron: RGD PMID:19815055 RGD:9693680 NCBI chr 2:188,458,851...188,471,916
Ensembl chr 2:188,454,853...188,471,988
JBrowse link
G Hdac1 histone deacetylase 1 IEP protein:increased activity:renal cortex: RGD PMID:19553350 RGD:9590229 NCBI chr 5:147,716,664...147,743,723
Ensembl chr 5:147,716,664...147,743,723
JBrowse link
G Hdac2 histone deacetylase 2 IEP protein:increased activity:renal cortex: RGD PMID:19553350 RGD:9590229 NCBI chr20:43,084,870...43,108,198
Ensembl chr20:43,084,870...43,108,198
JBrowse link
G Hdac4 histone deacetylase 4 IEP protein:increased activity:renal cortex: RGD PMID:19553350 RGD:9590229 NCBI chr 9:99,052,945...99,299,715
Ensembl chr 9:99,057,089...99,299,715
JBrowse link
G Hgf hepatocyte growth factor IEP protein:increased expression:kidney RGD PMID:16297324 RGD:2313568 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha IEP protein:increased expression:sciatic nerve (rat) RGD PMID:15663958 RGD:8694461 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hk1 hexokinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16123366 NCBI chr20:31,911,460...31,979,780
Ensembl chr20:31,912,262...31,956,649
JBrowse link
G Hmbs hydroxymethylbilane synthase IEP protein:decreased activity:liver (rat) RGD PMID:6688350 RGD:4144808 NCBI chr 8:48,667,278...48,674,673
Ensembl chr 8:48,667,275...48,674,748
JBrowse link
G Hmgb1 high mobility group box 1 IEP associated with Endotoxemia;protein:increased expression:serum
protein:increased expression, altered localization:retina, cytoplasm
RGD PMID:19959191, PMID:23261684 RGD:2316737, RGD:10402069 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Hmgcl 3-hydroxy-3-methylglutaryl-CoA lyase IEP protein:increased activity:liver (rat) RGD PMID:5667251 RGD:2326171 NCBI chr 5:154,294,841...154,308,582
Ensembl chr 5:154,294,806...154,308,640
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase IMP RGD PMID:15111316 RGD:2313760 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 IEP protein:increased expression:pancreas RGD PMID:18452227 RGD:2302233 NCBI chr 2:52,427,351...52,445,082
Ensembl chr 2:52,431,601...52,445,055
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 IEP protein:increased expression:liver (rat) RGD PMID:7902069 RGD:2326135 NCBI chr 2:200,452,623...200,480,785
Ensembl chr 2:200,452,624...200,479,423
JBrowse link
G Hmox1 heme oxygenase 1 IEP
ISO
CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:16123366 PMID:16959961 PMID:18375438 PMID:19804535, PMID:15734859 RGD:1582713 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha IEP
ISO
mRNA:decreased expression:kidney, liver
protein:increased expression:liver:
RGD PMID:18184923, PMID:19179483 RGD:2301838, RGD:12904769 NCBI chr 3:159,902,441...159,965,003
Ensembl chr 3:159,902,441...159,965,003
JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 IEP protein:increased expression:urinary bladder (rat) RGD PMID:18337374 RGD:9685410 NCBI chr 4:81,237,496...81,241,281
Ensembl chr 4:81,237,496...81,241,282
JBrowse link
G Hnrnpk heterogeneous nuclear ribonucleoprotein K treatment IDA RGD PMID:16837467 RGD:10002795 NCBI chr17:6,664,730...6,676,753
Ensembl chr17:6,665,659...6,676,654
JBrowse link
G Hp haptoglobin IEP protein:increased expression:serum RGD PMID:11072799 RGD:1626381 NCBI chr19:42,096,255...42,100,805
Ensembl chr19:42,097,995...42,100,804
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 IEP protein:decreased activity:liver (rat) RGD PMID:3043317 RGD:5135485 NCBI chr  X:158,196,640...158,228,815
Ensembl chr  X:158,197,149...158,228,749
JBrowse link
G Hras HRas proto-oncogene, GTPase IEP mRNA, protein:increased expression:retina blood vessel RGD PMID:18514235 RGD:2314841 NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14697232 NCBI chr13:111,946,626...111,996,536
Ensembl chr13:111,926,442...111,972,603
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 IEP mRNA:decreased expression:brain (rat) RGD PMID:21104931 RGD:5686396 NCBI chr 6:135,107,262...135,112,793
Ensembl chr 6:135,107,271...135,112,775
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 IEP RGD PMID:17280490 RGD:1624229 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
JBrowse link
G Hspg2 heparan sulfate proteoglycan 2 IEP mRNA:decreased expression:retina RGD PMID:9068943 RGD:1624265 NCBI chr 5:155,812,096...155,913,751 JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A IEP protein:increased expression:lung RGD PMID:21521772 RGD:5135278 NCBI chr15:56,666,152...56,732,469
Ensembl chr15:56,666,012...56,735,382
JBrowse link
G Iapp islet amyloid polypeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:16123366 NCBI chr 4:176,509,863...176,517,903
Ensembl chr 4:176,510,696...176,516,083
JBrowse link
G Icam1 intercellular adhesion molecule 1 treatment ISO
IEP
mRNA:increased expression:aorta
CTD Direct Evidence: marker/mechanism
protein:increased expression:serum
CTD PMID:14871415 PMID:20388520 PMID:24513509, PMID:18093596, PMID:20136425, PMID:18413153 RGD:2306988, RGD:8547703, RGD:2306987 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:16123366 NCBI chr 3:148,214,623...148,216,715
Ensembl chr 3:148,215,540...148,216,718
JBrowse link
G Ide insulin degrading enzyme IEP protein:decreased expression:cerebral cortex RGD PMID:29940507 RGD:13792791 NCBI chr 1:255,914,465...256,014,168
Ensembl chr 1:255,914,447...256,013,495
JBrowse link
G Ifnar1 interferon alpha and beta receptor subunit 1 IMP RGD PMID:27999109 RGD:12910492 NCBI chr11:31,640,407...31,666,839
Ensembl chr11:31,640,407...31,664,061
JBrowse link
G Ifnar1em1 interferon alpha and beta receptor subunit 1; CRISPR/Cas9 induced mutant 1 IMP RGD PMID:27999109 RGD:12910492
G Ifnar1em2 interferon alpha and beta receptor subunit 1; CRISPR/Cas9 induced mutant 2 IMP RGD PMID:27999109 RGD:12910492
G Ifng interferon gamma ISO
IEP
mRNA:increased expression:pancreas
CTD Direct Evidence: marker/mechanism
protein:increased expression:retina
CTD PMID:21340626, PMID:18789669, PMID:20213480 RGD:2311492, RGD:5147915 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Igf1 insulin-like growth factor 1 IEP
ISO
protein:decreased expression:cerebellum, serum
CTD Direct Evidence: therapeutic
mRNA,protein:decreased expression:corpus cavernosum:
protein:decreased expression:oviduct
protein:decreased expression:heart
CTD PMID:24632065, PMID:19382144, PMID:22133301, PMID:18676006, PMID:20555424 RGD:2306671, RGD:10046054, RGD:2311502, RGD:4142788 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igf1r insulin-like growth factor 1 receptor IEP
ISO
protein:decreased phosphorylation:heart
protein:decreased expression:oviduct
RGD PMID:20555424, PMID:18676006 RGD:4142788, RGD:2311502 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Igf2 insulin-like growth factor 2 treatment ISO
IEP
DNA, mRNA:hypermethylation, decreased expression
mRNA:decreased expression:brain
protein:increased expression:oviduct
protein:increased expression:multiple
RGD PMID:18724775, PMID:23364485, PMID:10686593, PMID:18676006, PMID:17184497 RGD:2311511, RGD:10402565, RGD:5509973, RGD:2311502, RGD:2311513 NCBI chr 1:215,828,102...215,839,081
Ensembl chr 1:215,828,102...215,846,911
JBrowse link
G Igf2r insulin-like growth factor 2 receptor ISO protein:increased expression:oviduct RGD PMID:18676006 RGD:2311502 NCBI chr 1:48,176,095...48,264,482
Ensembl chr 1:48,176,106...48,264,477
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 treatment ISO
IMP
IEP
protein:increased expression:skeletal muscle
mRNA, protein:increased expression:penis
RGD PMID:16180585, PMID:25582342, PMID:18068478 RGD:2313766, RGD:12743617, RGD:2289159 NCBI chr14:87,457,647...87,465,374
Ensembl chr14:87,457,647...87,465,374
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta IDA protein:increased phosphorylation:liver RGD PMID:20362663 RGD:7495777 NCBI chr16:74,177,233...74,230,809
Ensembl chr16:74,177,215...74,230,815
JBrowse link
G Il10 interleukin 10 IEP
ISO
protein:increase expression:serum RGD PMID:18787467, PMID:18779928 RGD:2308945, RGD:2308946 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il17a interleukin 17A IEP protein:increased expression:gingiva (rat) RGD PMID:21826658 RGD:9068940 NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786
JBrowse link
G Il1a interleukin 1 alpha IEP protein:increased expression:heart RGD PMID:20555424 RGD:4142788 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta IEP
ISO
IDA
mRNA:increased expression:skeletal muscle
CTD Direct Evidence: marker/mechanism
CTD PMID:12123627, PMID:17669395, PMID:23197974 RGD:1626620, RGD:7175529 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO human gene in a rat model RGD PMID:19545727, PMID:17221214, PMID:8037760 RGD:6907397, RGD:8551855, RGD:6907425 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
JBrowse link
G Il2 interleukin 2 IEP protein:increased expression:retina RGD PMID:20213480 RGD:5147915 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il2ra interleukin 2 receptor subunit alpha IDA RGD PMID:18503494 RGD:2311530 NCBI chr17:70,500,672...70,547,929
Ensembl chr17:70,499,083...70,548,071
JBrowse link
G Il4 interleukin 4 treatment IEP RGD PMID:25191525 RGD:10402795 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il4r interleukin 4 receptor ISO RGD PMID:12165974 RGD:4889983 NCBI chr 1:196,942,343...196,967,221
Ensembl chr 1:196,942,364...196,967,220
JBrowse link
G Il6 interleukin 6 IEP
ISO
IDA
protein:increased expression:heart
CTD Direct Evidence: marker/mechanism
protein:increased expression:extracellular space (rat)
protein:increased expression:blood
CTD PMID:22138235, PMID:20555424, PMID:24582317, PMID:19328014, PMID:18976114 RGD:4142788, RGD:11049554, RGD:2307252, RGD:2306984 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Insig1 insulin induced gene 1 ISO RGD PMID:16327801 RGD:2308858 NCBI chr 4:342,302...350,515
Ensembl chr 4:342,302...350,515
JBrowse link
G Insr insulin receptor disease_progression
treatment
IDA
IEP
ISO
protein:decreased expression:erythrocyte (rat)
mRNA:increased expression:liver nuclei, liver cell membrane (rat)
associated with streptozocin;protein:altered activity:liver plasma membrane (rat)
CTD Direct Evidence: marker/mechanism
mRNA, protein:increased expression:liver, adipose tissue (rat)
protein:decreased expression:kidney
CTD PMID:9243097 PMID:22138235, PMID:18376071, PMID:1280238, PMID:2180315, PMID:23874448, PMID:18638371, PMID:17855644 RGD:2307339, RGD:15036814, RGD:14981592, RGD:10403045, RGD:2307025, RGD:2290475 NCBI chr12:1,682,527...1,816,414
Ensembl chr12:1,680,957...1,816,414
JBrowse link
G Irs1 insulin receptor substrate 1 treatment IDA
ISO
IEP
CTD Direct Evidence: marker/mechanism
mRNA, protein:decreased expression:multiple
CTD PMID:22138235, PMID:22983684, PMID:22820932 RGD:7207061, RGD:7207063 NCBI chr 9:88,033,668...88,086,488
Ensembl chr 9:88,033,668...88,086,488
JBrowse link
G Irs2 insulin receptor substrate 2 IEP
ISO
protein:decreased phosphorylation:heart
CTD Direct Evidence: marker/mechanism
CTD PMID:25808216, PMID:20555424 RGD:4142788 NCBI chr16:83,824,515...83,848,569
Ensembl chr16:83,824,430...83,848,684
JBrowse link
G Isg15 ISG15 ubiquitin-like modifier IEP RGD PMID:20973890 RGD:5490977 NCBI chr 5:173,624,862...173,629,124
Ensembl chr 5:173,624,310...173,626,248
JBrowse link
G Itga3 integrin subunit alpha 3 IEP protein:decreased expression:renal cortex (rat) RGD PMID:20525748 RGD:2325818 NCBI chr10:82,855,841...82,887,755
Ensembl chr10:82,855,613...82,887,497
JBrowse link
G Itgb1 integrin subunit beta 1 IEP protein:decreased expression:epidermal stem cell (rat) RGD PMID:20187441 RGD:2325322 NCBI chr19:61,677,512...61,725,537
Ensembl chr19:61,677,542...61,725,535
JBrowse link
G Itgb3 integrin subunit beta 3 IEP protein:increased expression:aorta: RGD PMID:12606526 RGD:8693385 NCBI chr10:92,667,869...92,783,413
Ensembl chr10:92,667,869...92,783,410
JBrowse link
G Jak3 Janus kinase 3 IEP protein:increased expression:retina RGD PMID:21575160 RGD:11533943 NCBI chr16:20,107,471...20,120,678
Ensembl chr16:20,109,200...20,120,668
JBrowse link
G Kcna2 potassium voltage-gated channel subfamily A member 2 IEP RGD PMID:17982915 RGD:7242761 NCBI chr 2:209,838,607...209,852,471
Ensembl chr 2:209,838,869...209,852,471
JBrowse link
G Kcna5 potassium voltage-gated channel subfamily A member 5 IEP RGD PMID:17982915 RGD:7242761 NCBI chr 4:159,077,195...159,079,003
Ensembl chr 4:159,077,195...159,079,003
JBrowse link
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 IEP mRNA:decreased expression:left heart ventricle RGD PMID:19267230 RGD:7243942 NCBI chr11:32,434,786...32,447,264
Ensembl chr11:32,440,237...32,447,259
JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 IEP
ISO
protein:decreased expression:brain
CTD Direct Evidence: marker/mechanism
CTD PMID:16123366, PMID:23785408 RGD:7296920 NCBI chr 1:102,103,093...102,107,134
Ensembl chr 1:102,103,094...102,106,127
JBrowse link
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 IEP mRNA, protein:decreased expression:aorta, smooth muscle RGD PMID:24589593 RGD:10412030 NCBI chr15:344,204...1,048,849
Ensembl chr15:344,360...1,047,956
JBrowse link
G Kcnmb1 potassium calcium-activated channel subfamily M regulatory beta subunit 1 IEP protein:decreased expression:aorta, smooth muscle RGD PMID:24589593 RGD:10412030 NCBI chr10:18,910,586...18,922,856
Ensembl chr10:18,906,010...18,919,639
JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 IEP mRNA, protein:increased expression:aorta, smooth muscle RGD PMID:24589593 RGD:10412030 NCBI chr 1:81,227,855...81,245,986
Ensembl chr 1:81,230,612...81,245,996
JBrowse link
G Kdr kinase insert domain receptor ISO
IEP
mRNA:decreased expression:skeletal muscle
mRNA:increased expression:retina
mRNA:decreased expression:heart
RGD PMID:16816123, PMID:22121831, PMID:16741021 RGD:2313725, RGD:5684538, RGD:2313724 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183
JBrowse link
G Khk ketohexokinase IEP RGD PMID:6088170 RGD:2302253 NCBI chr 6:26,810,577...26,821,013
Ensembl chr 6:26,810,579...26,820,959
JBrowse link
G Kif1a kinesin family member 1A IEP mRNA:increased expression:hippocampus RGD PMID:23776493 RGD:11059542 NCBI chr 9:100,171,851...100,253,626
Ensembl chr 9:100,171,772...100,253,609
JBrowse link
G Kif5b kinesin family member 5B IEP mRNA:increased expression:hippocampus RGD PMID:23776493 RGD:11059542 NCBI chr17:54,181,416...54,219,048
Ensembl chr17:54,181,419...54,212,096
JBrowse link
G Klk1 kallikrein 1 IEP mRNA:decreased expression:myocardium RGD PMID:10604522 RGD:1641812 NCBI chr 1:100,131,562...100,135,556
Ensembl chr 1:100,059,967...100,203,329
Ensembl chr 1:100,059,967...100,203,329
Ensembl chr 1:100,059,967...100,203,329
JBrowse link
G Kmt5c lysine methyltransferase 5C IEP mRNA:increased expression:retina RGD PMID:21357467 RGD:9586742 NCBI chr 1:72,666,662...72,674,271
Ensembl chr 1:72,666,665...72,674,271
JBrowse link
G Lcn2 lipocalin 2 IEP mRNA:increased expression:retina (rat)
protein:increased expression:urine
RGD PMID:15623795, PMID:23085980 RGD:2316515, RGD:7245484 NCBI chr 3:11,414,189...11,417,534
Ensembl chr 3:11,414,186...11,417,546
JBrowse link
G Lct lactase IDA RGD PMID:16021836 RGD:1600251 NCBI chr13:44,998,414...45,040,593
Ensembl chr13:44,998,414...45,040,593
JBrowse link
G Ldlr low density lipoprotein receptor IEP mRNA:decreased expression:liver RGD PMID:18054320 RGD:2324626 NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903
JBrowse link
G Lep leptin onset IMP
ISO
IDA
CTD Direct Evidence: marker/mechanism CTD PMID:28242381 PMID:31313498 PMID:31483951, PMID:19491210, PMID:19428774, PMID:20695765 RGD:2311124, RGD:2311126, RGD:5128579 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Lepr leptin receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:15093691 PMID:16427799 PMID:17065336 PMID:19452630 PMID:19478208 PMID:20567778 PMID:22933112 PMID:24263156 PMID:26939912 PMID:27151219 PMID:30635400 NCBI chr 5:120,503,475...120,682,281
Ensembl chr 5:120,564,645...120,682,221
JBrowse link
G Lgals3 galectin 3 treatment IEP RGD PMID:21249158 RGD:9685210 NCBI chr15:24,153,602...24,165,537
Ensembl chr15:24,141,651...24,165,537
JBrowse link
G Lipc lipase C, hepatic type IDA
IEP
protein:decreased activity:liver (rat) RGD PMID:18758746, PMID:1868959 RGD:2307432, RGD:2308849 NCBI chr 8:77,272,582...77,398,485
Ensembl chr 8:77,272,570...77,398,248
JBrowse link
G Litaf lipopolysaccharide-induced TNF factor IEP protein:increased expression:retina RGD PMID:21575160 RGD:11533943 NCBI chr10:4,753,546...4,763,272
Ensembl chr10:4,719,713...4,763,510
JBrowse link
G Lpin1 lipin 1 IEP mRNA:increased expression:skeletal muscle RGD PMID:14718385 RGD:1641826 NCBI chr 6:41,796,214...41,905,149
Ensembl chr 6:41,799,749...41,870,046
JBrowse link
G Lpl lipoprotein lipase treatment IEP
IDA
RGD PMID:18780778, PMID:27158912 RGD:2313303, RGD:13794379 NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496
JBrowse link
G Lrp2 LDL receptor related protein 2 IEP protein:decreased expression:kidney, proximal convoluted tubule, apical plasma membrane RGD PMID:11685557 RGD:1641843 NCBI chr 3:55,665,153...55,822,484
Ensembl chr 3:55,665,145...55,822,551
JBrowse link
G Ltbp1 latent transforming growth factor beta binding protein 1 IEP RGD PMID:17574405 RGD:2302087 NCBI chr 6:21,203,502...21,600,441
Ensembl chr 6:21,203,502...21,600,451
JBrowse link
G Mafa MAF bZIP transcription factor A treatment ISO RGD PMID:28487936 RGD:13506743 NCBI chr 7:116,779,368...116,781,815
Ensembl chr 7:116,780,681...116,781,766
JBrowse link
G Map2k3 mitogen activated protein kinase kinase 3 IEP mRNA:increased expression:kidney, glomerulus RGD PMID:11473637 RGD:7495813 NCBI chr10:45,089,455...45,110,802
Ensembl chr10:47,182,433...47,203,753
JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 IEP mRNA:increased expression:kidney, glomerulus RGD PMID:11473637 RGD:7495813 NCBI chr10:98,707,160...98,823,054
Ensembl chr10:98,706,960...98,823,287
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18342293 NCBI chr 1:15,412,603...15,613,752
Ensembl chr 1:15,412,603...15,613,746
JBrowse link
G Mapk1 mitogen activated protein kinase 1 IEP
IDA
protein:decreased phosphorylation:cornea RGD PMID:22045654, PMID:21330660 RGD:7243969, RGD:5131482 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 IDA protein:decreased phosphorylation:cornea RGD PMID:21330660 RGD:5131482 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapt microtubule-associated protein tau treatment IDA RGD PMID:28400135 RGD:13800903 NCBI chr10:92,289,002...92,386,517
Ensembl chr10:92,288,910...92,386,517
JBrowse link
G Mas1 MAS1 proto-oncogene, G protein-coupled receptor IEP mRNA:increased expression:renal cortex (rat) RGD PMID:18679036 RGD:2313799 NCBI chr 1:48,076,761...48,108,218
Ensembl chr 1:48,077,033...48,108,216
JBrowse link
G Mbp myelin basic protein IDA RGD PMID:23667870 RGD:7327197 NCBI chr18:79,326,738...79,437,310
Ensembl chr18:79,326,738...79,437,310
JBrowse link
G Mdm2 MDM2 proto-oncogene IEP protein:increased degradation:myocardium RGD PMID:23530877 RGD:10412313 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Mef2a myocyte enhancer factor 2a IEP mRNA:increased expression:heart RGD PMID:18413674 RGD:2312263 NCBI chr 1:128,207,715...128,341,681
Ensembl chr 1:128,209,971...128,341,263
JBrowse link
G Mef2c myocyte enhancer factor 2C IEP mRNA:increased expression:heart RGD PMID:18413674 RGD:2312263 NCBI chr 2:11,658,534...11,822,788
Ensembl chr 2:11,658,568...11,822,787
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase IEP mRNA, protein:increased expression:kidney, tubule, epithelium (rat) RGD PMID:8997394 RGD:2317555 NCBI chr 4:44,747,467...44,854,628
Ensembl chr 4:44,774,741...44,852,665
JBrowse link
G Mfge8 milk fat globule EGF and factor V/VIII domain containing ISO CTD Direct Evidence: marker/mechanism CTD PMID:21505870 NCBI chr 1:140,845,478...140,860,882
Ensembl chr 1:140,845,465...140,860,894
JBrowse link
G Mfn2 mitofusin 2 treatment IEP protein:increased expression:heart, mitochondrion (rat) RGD PMID:28483572, PMID:27998959 RGD:12910731, RGD:12910739 NCBI chr 5:164,684,244...164,715,414
Ensembl chr 5:164,684,509...164,714,145
JBrowse link
G Mif macrophage migration inhibitory factor ISO protein:increased expression:pancreatic islet RGD PMID:15790730 RGD:1641951 NCBI chr20:13,715,219...13,732,980
Ensembl chr20:13,732,198...13,732,859
JBrowse link
G Mmp1 matrix metallopeptidase 1 IEP protein:increased expression:periodontal ligament, alveolar bone of mandible (rat) RGD PMID:20082587 RGD:7207377 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Mmp2 matrix metallopeptidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21963884 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp9 matrix metallopeptidase 9 treatment IEP
ISO
protein:increased expression:kidney
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:retina
CTD PMID:21963884 PMID:22191573, PMID:17569353, PMID:23089644, PMID:23423566 RGD:2290354, RGD:8547974, RGD:8547881 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mpo myeloperoxidase IEP
ISO
protein:increased activity:liver:
CTD Direct Evidence: marker/mechanism
CTD PMID:20388520, PMID:18436980 RGD:2317971 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II ISO CTD Direct Evidence: marker/mechanism CTD PMID:14563825 NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689
JBrowse link
G Mt-cyb mitochondrially encoded cytochrome b IEP mRNA:decreased expression:heart RGD PMID:15126286 RGD:1578536 NCBI chr MT:14,136...15,278
Ensembl chr MT:14,136...15,278
JBrowse link
G Mt-nd1 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14563825 NCBI chr MT:2,740...3,694
Ensembl chr MT:2,740...3,694
JBrowse link
G Mthfr methylenetetrahydrofolate reductase IEP protein:decreased activity:kidney (rat) RGD PMID:9836532 RGD:6893689 NCBI chr 5:164,844,642...164,864,360
Ensembl chr 5:164,845,925...164,860,910
JBrowse link
G Mtor mechanistic target of rapamycin kinase IDA protein:hyperphosphorylation:muscle RGD PMID:28536139 RGD:13506787 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase IEP protein:decreased activity:liver RGD PMID:18936199 RGD:7207081 NCBI chr17:66,210,444...66,295,014
Ensembl chr17:66,210,461...66,295,014
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor IEP mRNA:increased expression:renal cortex (rat) RGD PMID:18030501 RGD:7207459 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase IEP protein:decreased expression:fat cell RGD PMID:18410550 RGD:2311099 NCBI chr 6:52,122,085...52,156,473
Ensembl chr 6:52,122,085...52,156,472
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14871415 PMID:16380483 NCBI chr12:25,497,104...25,506,300
Ensembl chr12:25,497,104...25,506,300
JBrowse link
G Ncf2 neutrophil cytosolic factor 2 IDA
IEP
protein:altered localization:glomerulus
protein:increased expression:heart, membrane fraction
RGD PMID:14514646, PMID:18061195 RGD:2314451, RGD:2314434 NCBI chr13:70,226,441...70,259,019
Ensembl chr13:70,226,647...70,257,576
JBrowse link
G Ndufs2 NADH:ubiquinone oxidoreductase core subunit S2 IEP protein:decreased expression:dorsal root ganglia (rat) RGD PMID:20876714 RGD:6484699 NCBI chr13:89,606,848...89,623,506
Ensembl chr13:89,606,840...89,619,398
JBrowse link
G Ndufs3 NADH:ubiquinone oxidoreductase core subunit S3 IEP protein:decreased expression:dorsal root ganglia (rat)
mRNA, protein:decreased expression:brain
RGD PMID:20876714, PMID:22387129 RGD:6484699, RGD:13824971 NCBI chr 3:79,721,686...79,728,863
Ensembl chr 3:79,721,694...79,728,879
JBrowse link
G Nefh neurofilament heavy treatment IEP RGD PMID:12941778 RGD:9698428 NCBI chr14:85,181,572...85,191,557
Ensembl chr14:85,181,572...85,191,557
JBrowse link
G Nefm neurofilament medium treatment IEP RGD PMID:12941778 RGD:9698428 NCBI chr15:44,855,307...44,860,604
Ensembl chr15:44,855,310...44,860,604
JBrowse link
G Neurod1 neuronal differentiation 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16123366 NCBI chr 3:66,414,314...66,417,617
Ensembl chr 3:66,414,308...66,417,741
JBrowse link
G Neurog3 neurogenin 3 ISO RGD PMID:19819964 RGD:2313774 NCBI chr20:31,761,419...31,762,893
Ensembl chr20:31,761,405...31,762,893
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 treatment ISO
IEP
protein:increased localization:blood, mononuclear cell, nucleus RGD PMID:22869588, PMID:23331247, PMID:24740568 RGD:10412694, RGD:7244270, RGD:10412720 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkb2 nuclear factor kappa B subunit 2 IEP RGD PMID:18633731 RGD:2298775 NCBI chr 1:266,050,634...266,059,277
Ensembl chr 1:266,053,002...266,059,256
JBrowse link
G Nfkbia NFKB inhibitor alpha treatment IEP
IDA
protein:decreased expression:kidney RGD PMID:22483164, PMID:20188823 RGD:10413864, RGD:10413873 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Ngf nerve growth factor IEP mRNA, protein:decreased expression:sciatic nerve
protein:increased expression:retina
RGD PMID:19149268, PMID:21136036 RGD:2303795, RGD:5144144 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453
JBrowse link
G Ngfr nerve growth factor receptor IEP protein:increased expression:retina RGD PMID:21136036 RGD:5144144 NCBI chr10:83,389,828...83,408,061
Ensembl chr10:83,389,847...83,408,061
JBrowse link
G Nkx6-1 NK6 homeobox 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16123366 NCBI chr14:9,555,264...9,562,197
Ensembl chr14:9,555,264...9,562,189
JBrowse link
G Nos1 nitric oxide synthase 1 IDA protein:decreased dimerization:stomach RGD PMID:17347455 RGD:1642144 NCBI chr12:44,214,949...44,405,530
Ensembl chr12:44,213,943...44,520,341
JBrowse link
G Nos2 nitric oxide synthase 2 no_association IEP
ISO
associated with Infarction, Middle Cerebral Artery; protein:increased expression:brain (rat)
CTD Direct Evidence: marker/mechanism
protein:increased expression:renal glomerulus (rat)
CTD PMID:16380483 PMID:16959961, PMID:21993016, PMID:9349594 RGD:5509105, RGD:5509107 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nos3 nitric oxide synthase 3 treatment IDA
IEP
ISO
CTD Direct Evidence: marker/mechanism
protein:decreased expression:thoracic aorta (mouse)
protein:increased expression:heart
CTD PMID:11696579 PMID:14871415 PMID:15490108 PMID:16959961 PMID:18266981 PMID:19478208 PMID:22191573 PMID:22933112, PMID:18825362, PMID:28976888, PMID:21050844, PMID:21050844, PMID:18287592 RGD:4892007, RGD:13450939, RGD:7777108, RGD:7777108, RGD:2292100 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Nox4 NADPH oxidase 4 IEP protein:increased expression:aorta RGD PMID:19686728 RGD:2324658 NCBI chr 1:150,796,359...150,976,186
Ensembl chr 1:150,797,084...150,976,194
JBrowse link
G Npc1l1 NPC1 like intracellular cholesterol transporter 1 IEP mRNA:increased expression:intestine, liver RGD PMID:17292734 RGD:1642185 NCBI chr14:86,345,946...86,560,694
Ensembl chr14:86,345,953...86,560,694
JBrowse link
G Nppa natriuretic peptide A IEP protein:decreased expression:retina
protein:increased expression:plasma, kidney, heart;
RGD PMID:15789000, PMID:17151304 RGD:1580773, RGD:7248602 NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705
JBrowse link
G Nppb natriuretic peptide B IEP protein:increased expression:atrium myocardium, plasma RGD PMID:17151299 RGD:1642199 NCBI chr 5:164,796,176...164,797,538
Ensembl chr 5:164,796,185...164,797,531
JBrowse link
G Npy neuropeptide Y IEP protein:increased expression:paraventricular nucleus of hypothalamus RGD PMID:21042571 RGD:10448960 NCBI chr 4:79,557,856...79,565,059
Ensembl chr 4:79,557,854...79,565,097
JBrowse link
G Npy1r neuropeptide Y receptor Y1 IEP RGD PMID:18201831 RGD:10448967 NCBI chr16:24,779,480...24,789,131
Ensembl chr16:24,779,477...24,788,740
JBrowse link
G Npy2r neuropeptide Y receptor Y2 IEP RGD PMID:18201831 RGD:10448967 NCBI chr 2:181,528,949...181,538,145
Ensembl chr 2:181,530,832...181,531,978
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 ISO CTD Direct Evidence: therapeutic CTD PMID:23458895 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 IEP mRNA:decreased expression:liver RGD PMID:15047603 RGD:1625080 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 treatment IEP RGD PMID:20636876 RGD:9835393 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 IEP protein:increased expression:placenta RGD PMID:21744335 RGD:12879479 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Nrp1 neuropilin 1 ISO mRNA:decreased expression:skeletal muscle RGD PMID:16816123 RGD:2313725 NCBI chr19:61,332,351...61,486,166
Ensembl chr19:61,332,351...61,485,858
JBrowse link
G Nt5e 5' nucleotidase, ecto IEP protein:increased expression:cerebral cortex, synaptosome (rat) RGD PMID:19723569 RGD:5134343 NCBI chr 8:95,969,002...96,012,733
Ensembl chr 8:95,968,652...96,012,696
JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 IEP protein:increased tyrosine nitration, decreased tyrosine phosphorylation:retina RGD PMID:21136036, PMID:22044876 RGD:5144144, RGD:5684337 NCBI chr 2:187,143,568...187,160,373
Ensembl chr 2:187,143,568...187,160,373
JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 IEP mRNA:decreased expression:dorsal root ganglion RGD PMID:9541170 RGD:2325654 NCBI chr 1:139,890,537...140,262,503
Ensembl chr 1:139,890,560...140,262,503
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase IEP
ISO
protein:altered localization:pancreatic islet RGD PMID:18676009, PMID:18599524, PMID:15677345 RGD:2317137, RGD:8657153, RGD:8657146 NCBI chr 4:145,282,828...145,289,367
Ensembl chr 4:145,282,797...145,289,326
JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase treatment IDA RGD PMID:15561949 RGD:9590198 NCBI chr  X:71,540,870...71,585,906
Ensembl chr  X:71,528,988...71,585,908
JBrowse link
G Oprk1 opioid receptor, kappa 1 IEP protein:increased expression:sciatic nerve, peroneal nerve: RGD PMID:16924480 RGD:9834947 NCBI chr 5:13,742,655...13,760,460
Ensembl chr 5:13,744,658...13,760,305
JBrowse link
G Oprm1 opioid receptor, mu 1 IDA RGD PMID:16901587 RGD:2316626 NCBI chr 1:43,454,803...43,704,948
Ensembl chr 1:43,454,803...43,704,948
JBrowse link
G Osbp oxysterol binding protein IDA protein:increased tyrosine phosphorylation:aorta RGD PMID:18230613 RGD:2291921 NCBI chr 1:228,395,237...228,425,366
Ensembl chr 1:228,395,558...228,425,361
JBrowse link
G Otc ornithine transcarbamylase IEP protein:decreased activity:small intestine (rat) RGD PMID:9628242 RGD:4144123 NCBI chr  X:13,524,804...13,601,074
Ensembl chr  X:13,524,607...13,601,069
JBrowse link
G Oxct1 3-oxoacid CoA transferase 1 IEP protein:decreased activity:heart, mitochondrion (rat) RGD PMID:3548709 RGD:2326100 NCBI chr 2:53,859,738...54,007,733
Ensembl chr 2:53,859,737...54,007,756
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 ISO RGD PMID:18657544 RGD:2312287 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pax6 paired box 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16123366 NCBI chr 3:95,700,241...95,728,682
Ensembl chr 3:95,707,386...95,728,624
JBrowse link
G Pc pyruvate carboxylase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16123366 NCBI chr 1:219,759,157...219,859,854
Ensembl chr 1:219,759,183...219,859,848
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 IDA
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:20363216, PMID:17651728 RGD:2311641 NCBI chr 3:171,213,936...171,219,885
Ensembl chr 3:171,213,936...171,219,871
JBrowse link
G Pcsk1 proprotein convertase subtilisin/kexin type 1 IEP
ISO
mRNA, protein:increased expression:spleen, spleen white pulp (rat)
protein:increased expression:pancreatic alpha cell (mouse)
mRNA, protein:increased expression:spleen (mouse)
RGD PMID:11730986, PMID:17698597, PMID:11730986 RGD:2308905, RGD:2308931, RGD:2308905 NCBI chr 2:91,450,162...91,497,091
Ensembl chr 2:91,450,162...91,497,091
JBrowse link
G Pcsk2 proprotein convertase subtilisin/kexin type 2 IEP
ISO
mRNA:increased expression:spleen
CTD Direct Evidence: marker/mechanism
CTD PMID:16123366, PMID:11730986 RGD:2308905 NCBI chr 3:137,618,891...137,923,385
Ensembl chr 3:137,618,898...137,925,605
JBrowse link
G Pde3a phosphodiesterase 3A IEP mRNA, protein:increased expression:mesenteric artery RGD PMID:12793980 RGD:2300416 NCBI chr 4:175,431,904...175,703,844
Ensembl chr 4:175,431,904...175,700,238
JBrowse link
G Pde5a phosphodiesterase 5A IMP RGD PMID:19542492 RGD:2314461 NCBI chr 2:226,899,604...227,044,916
Ensembl chr 2:226,900,619...227,041,576
JBrowse link
G Pdgfb platelet derived growth factor subunit B IEP
IDA
ISO
mRNA:increased expression:glomerulus
mRNA: increased expression: mesenteric artery
mRNA:increased expression:retina
mRNA:decreased expression:retina
RGD PMID:8094359, PMID:9763208, PMID:21367419, PMID:12606528, PMID:14685146 RGD:2311650, RGD:10449499, RGD:6483042, RGD:1581759, RGD:2311648 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta IEP protein:increased expression:glomerulus RGD PMID:10802145 RGD:2311654 NCBI chr18:56,364,586...56,406,381
Ensembl chr18:56,364,620...56,406,381
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14563825 NCBI chr 4:30,546,772...30,556,774
Ensembl chr 4:30,546,664...30,556,814
JBrowse link
G Pdp2 pyruvate dehydrogenase phosphatase catalytic subunit 2 IEP RGD PMID:12765946 RGD:1582364 NCBI chr19:597,427...601,556
Ensembl chr19:597,427...601,469
JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 IMP
ISO
IEP
IDA
CTD Direct Evidence: marker/mechanism
protein:increased expression:pancreatic delta cell (rat)
protein:increased expression:pancreas (rat)
CTD PMID:16123366, PMID:17460716, PMID:15561947, PMID:14988244, PMID:17235568, PMID:17226789 RGD:2311224, RGD:2311226, RGD:1357906, RGD:2311225, RGD:2311311 NCBI chr12:9,496,044...9,501,211
Ensembl chr12:9,496,044...9,501,213
JBrowse link
G Pdyn prodynorphin IEP protein:increased expression:sciatic nerve, peroneal nerve, tibial nerve, footpad skin: RGD PMID:16924480 RGD:9834947 NCBI chr 3:122,194,327...122,206,671
Ensembl chr 3:122,194,329...122,206,671
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 IEP protein:decreased expression:corpus callosum, endothelium (rat) RGD PMID:21967314 RGD:6771179 NCBI chr10:94,850,971...94,913,202 JBrowse link
G Pemt phosphatidylethanolamine N-methyltransferase IEP protein:increased expression:liver RGD PMID:17116711 RGD:1642370 NCBI chr10:46,339,821...46,404,640
Ensembl chr10:46,339,821...46,404,642
JBrowse link
G Pfas phosphoribosylformylglycinamidine synthase IEP protein:increased activity:liver (rat) RGD PMID:3043317 RGD:5135485 NCBI chr10:55,571,881...55,593,384
Ensembl chr10:55,571,118...55,589,978
JBrowse link
G Pfkm phosphofructokinase, muscle ISO CTD Direct Evidence: marker/mechanism CTD PMID:14563825 NCBI chr 7:139,702,066...139,722,132
Ensembl chr 7:139,685,573...139,722,132
JBrowse link
G Pgf placental growth factor IEP mRNA, protein:decreased expression:placenta, trophoblast cell RGD PMID:17917370 RGD:6483782 NCBI chr 6:108,994,016...109,004,598
Ensembl chr 6:108,994,018...109,004,598
JBrowse link
G Phka1 phosphorylase kinase regulatory subunit alpha 1 IDA RGD PMID:11692172 RGD:1599897 NCBI chr  X:72,377,020...72,515,385
Ensembl chr  X:72,377,021...72,515,366
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 IEP protein:increased expression:gastrocnemius (rat) RGD PMID:18430054 RGD:2307338 NCBI chr 2:31,742,326...31,826,882
Ensembl chr 2:31,745,088...31,826,867
JBrowse link
G Pklr pyruvate kinase L/R IEP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:20363216, PMID:16900249 RGD:1625589 NCBI chr 2:188,449,158...188,458,034
Ensembl chr 2:188,449,210...188,459,592
JBrowse link
G Plcb3 phospholipase C beta 3 IEP protein:decreased expression:heart left ventricle RGD PMID:15362504 RGD:2314509 NCBI chr 1:222,207,887...222,224,993
Ensembl chr 1:222,209,575...222,224,910
JBrowse link
G Plcg1 phospholipase C, gamma 1 IEP protein:increased tyrosine phosphorylation:lens RGD PMID:17612968 RGD:2299877 NCBI chr 3:156,727,642...156,758,307
Ensembl chr 3:156,727,642...156,758,307
JBrowse link
G Pnmt phenylethanolamine-N-methyltransferase IEP protein:increased expression:adrenal gland (rat) RGD PMID:16396986 RGD:5130724 NCBI chr10:86,340,893...86,342,501
Ensembl chr10:86,340,940...86,342,858
JBrowse link
G Polg DNA polymerase gamma, catalytic subunit IEP
ISO
IDA
mRNA,protein:decreased expression:retina,mitochondrion:
DNA:hypermethylation:promoter:
RGD PMID:22743328, PMID:22229649, PMID:22743328 RGD:8694093, RGD:8694187, RGD:8694093 NCBI chr 1:141,172,117...141,188,893
Ensembl chr 1:141,172,531...141,188,031
JBrowse link
G Polg2 DNA polymerase gamma 2, accessory subunit ISO mRNA,protein:decreased expression:retina,mitochondrion: RGD PMID:22229649 RGD:8694187 NCBI chr10:94,968,836...94,979,259
Ensembl chr10:94,968,836...94,979,259
JBrowse link
G Pon1 paraoxonase 1 ISO RGD PMID:18358245, PMID:18358245 RGD:2313268, RGD:2313268 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:12967931 PMID:14563825 PMID:23090186 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta IEP mRNA, protein:decreased expression:heart RGD PMID:18573863 RGD:2313781 NCBI chr20:7,818,289...7,883,482
Ensembl chr20:7,818,289...7,885,333
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma IEP
ISO
mRNA:altered expression:aorta, kidney cortex, retina
CTD Direct Evidence: marker/mechanism
protein:decreased expression:retina
CTD PMID:12967931 PMID:16123366 PMID:21757225, PMID:18641696, PMID:18806296 RGD:2301849, RGD:2301844 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha treatment IEP
ISO
IMP
IDA
mRNA:decreased expression:pancreatic islet
CTD Direct Evidence: marker/mechanism
protein:decreased expression:dorsal root ganglia (mouse)
CTD PMID:14563825, PMID:18270681, PMID:19520786, PMID:22561641, PMID:23272147 RGD:2311391, RGD:2311445, RGD:7242175, RGD:7241845 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
JBrowse link
G Ppat phosphoribosyl pyrophosphate amidotransferase IEP protein:increased activity:kidney (rat) RGD PMID:2451505 RGD:5135016 NCBI chr14:33,580,541...33,614,919
Ensembl chr14:33,580,541...33,614,919
JBrowse link
G Prkca protein kinase C, alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:12198386 NCBI chr10:96,186,509...96,585,168
Ensembl chr10:96,191,133...96,584,947
JBrowse link
G Prkcb protein kinase C, beta IEP protein:increased expression:myocardium RGD PMID:17250813 RGD:1625511 NCBI chr 1:192,233,569...192,575,339
Ensembl chr 1:192,233,910...192,574,831
JBrowse link
G Prkcd protein kinase C, delta IEP
ISO
protein:increased expression:kidney
CTD Direct Evidence: marker/mechanism
CTD PMID:12198386, PMID:11576956 RGD:1642532 NCBI chr16:6,655,131...6,675,746
Ensembl chr16:6,655,120...6,675,746
JBrowse link
G Prkce protein kinase C, epsilon ISO CTD Direct Evidence: marker/mechanism CTD PMID:12198386 NCBI chr 6:9,483,400...9,973,396
Ensembl chr 6:9,790,422...9,973,396
JBrowse link
G Prkci protein kinase C, iota IEP protein:increased expression:ventricle myocardium, membrane fraction RGD PMID:14691046 RGD:2314944 NCBI chr 2:115,941,998...116,002,550
Ensembl chr 2:115,941,993...116,002,561
JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 treatment IEP protein:decreased expression:aorta RGD PMID:20186099, PMID:15939056 RGD:7775064, RGD:7777110 NCBI chr 1:248,982,039...250,300,952 JBrowse link
G Prkra protein activator of interferon induced protein kinase EIF2AK2 IEP RGD PMID:21897745 RGD:7777145 NCBI chr 3:63,489,081...63,507,918
Ensembl chr 3:63,489,074...63,507,926
JBrowse link
G Psmb9 proteasome 20S subunit beta 9 IEP mRNA:increased expression:hippocampus (rat) RGD PMID:20968039 RGD:9850284 NCBI chr20:3,973,424...3,978,845
Ensembl chr20:3,973,420...3,978,845
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 IEP protein:decreased expression:spinal cord RGD PMID:12086957 RGD:727386 NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IEP
ISO
CTD Direct Evidence: marker/mechanism
protein:increased expression:lung
protein:increased expression:sciatic nerve
CTD PMID:14514642 PMID:21414306, PMID:18706904, PMID:21521772, PMID:17720896 RGD:2300222, RGD:5135278, RGD:1642588 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ptprn protein tyrosine phosphatase, receptor type, N severity ISO RGD PMID:19513530 RGD:2313594 NCBI chr 9:82,446,626...82,462,314
Ensembl chr 9:82,446,633...82,461,903
JBrowse link
G Ptpru protein tyrosine phosphatase, receptor type, U IEP protein:decreased expression:glomerulus RGD PMID:16539708 RGD:1642656 NCBI chr 5:149,922,374...149,996,352
Ensembl chr 5:149,922,352...149,996,334
JBrowse link
G Pygm glycogen phosphorylase, muscle associated IDA protein:increased expression:sarcoplasmic reticulum RGD PMID:11692172 RGD:1599897 NCBI chr 1:221,756,325...221,771,142
Ensembl chr 1:221,756,286...221,771,143
JBrowse link
G Qdpr quinoid dihydropteridine reductase IEP protein:decreased activity:brain (rat) RGD PMID:2758679 RGD:5128601 NCBI chr14:70,164,682...70,178,284
Ensembl chr14:70,164,650...70,178,284
JBrowse link
G Ramp2 receptor activity modifying protein 2 IEP mRNA:increased expression:kidney RGD PMID:14717924 RGD:1642701 NCBI chr10:89,166,170...89,168,962
Ensembl chr10:89,166,890...89,168,965
JBrowse link
G Rap1b RAP1B, member of RAS oncogene family IEP protein:increased expression:renal glomerulus (rat) RGD PMID:12196513 RGD:10041023 NCBI chr 7:60,850,406...60,878,226
Ensembl chr 7:60,853,930...60,860,990
JBrowse link
G Rasgrf1 RAS protein-specific guanine nucleotide-releasing factor 1 IEP protein:decreased expression:brain, membrane (rat) RGD PMID:19002579 RGD:10003129 NCBI chr 8:97,277,250...97,405,095
Ensembl chr 8:97,277,456...97,405,102
JBrowse link
G Reg1a regenerating family member 1 alpha treatment IDA
IEP
protein:increased expression:pancreas, islet cell (rat) RGD PMID:8170952, PMID:8574288 RGD:9850123, RGD:9850143 NCBI chr 4:109,497,962...109,500,626
Ensembl chr 4:109,497,962...109,501,082
JBrowse link
G Reg3b regenerating family member 3 beta susceptibility ISO RGD PMID:21245462 RGD:9831432 NCBI chr 4:109,467,272...109,470,510
Ensembl chr 4:109,467,272...109,470,510
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit IEP
ISO
CTD Direct Evidence: marker/mechanism
protein:increased expression:nucleus, skeletal muscle, liver
CTD PMID:22138235, PMID:18633731, PMID:18500427 RGD:2298775, RGD:2298780 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Ren renin ISO CTD Direct Evidence: marker/mechanism CTD PMID:18829990 NCBI chr13:50,502,724...50,513,953
Ensembl chr13:50,502,724...50,514,151
JBrowse link
G Rgn regucalcin IEP protein:decreased expression:liver RGD PMID:9062895 RGD:9590177 NCBI chr  X:1,833,484...1,848,904
Ensembl chr  X:1,833,492...1,848,904
JBrowse link
G Rhoa ras homolog family member A IDA RGD PMID:17589825 RGD:1642825 NCBI chr 8:117,082,440...117,116,244
Ensembl chr 8:117,106,576...117,116,167
JBrowse link
G Rpe65 retinoid isomerohydrolase RPE65 IEP mRNA:decreased expression:retina (rat) RGD PMID:21862641 RGD:9585653 NCBI chr 2:266,141,581...266,169,197
Ensembl chr 2:266,141,581...266,169,197
JBrowse link
G Ryr2 ryanodine receptor 2 IDA RGD PMID:17027851 RGD:1599247 NCBI chr17:65,533,998...65,955,606
Ensembl chr17:65,535,403...65,955,606
JBrowse link
G S100a6 S100 calcium binding protein A6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16123366 NCBI chr 2:190,007,013...190,008,512
Ensembl chr 2:190,007,216...190,008,511
JBrowse link
G S100b S100 calcium binding protein B IEP protein:increased expression:cerebellum, cerebral cortex, hippocampus
protein:altered expression:hippocampus, astrocyte
RGD PMID:14583344, PMID:18708122 RGD:5508821, RGD:5508836 NCBI chr20:13,130,633...13,142,856
Ensembl chr20:13,130,636...13,142,856
JBrowse link
G S1pr2 sphingosine-1-phosphate receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22406263 NCBI chr 8:21,984,914...21,995,806
Ensembl chr 8:21,984,914...21,995,806
JBrowse link
G S1pr4 sphingosine-1-phosphate receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22406263 NCBI chr 7:11,077,411...11,079,687
Ensembl chr 7:11,077,411...11,079,687
JBrowse link
G S1pr5 sphingosine-1-phosphate receptor 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22406263 NCBI chr 8:22,268,635...22,273,708
Ensembl chr 8:22,268,657...22,270,647
JBrowse link
G Scap SREBF chaperone IEP RGD PMID:20973890 RGD:5490977 NCBI chr 8:118,551,869...118,628,650
Ensembl chr 8:118,570,503...118,628,651
JBrowse link
G Scp2 sterol carrier protein 2 treatment IEP RGD PMID:7628371 RGD:9850252 NCBI chr 5:127,647,934...127,735,703
Ensembl chr 5:127,620,274...127,735,739
JBrowse link
G Serpinc1 serpin family C member 1 treatment IDA
IEP
RGD PMID:22309505, PMID:24671746 RGD:11035271, RGD:11035293 NCBI chr13:78,806,107...78,820,375
Ensembl chr13:78,805,347...78,833,192
JBrowse link
G Serpine1 serpin family E member 1 ISO protein:increased expression:heart (mouse)
CTD Direct Evidence: marker/mechanism
CTD PMID:21757225, PMID:20630999 RGD:8547862 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Serpinf1 serpin family F member 1 IEP protein:decreased expression:platelet RGD PMID:19237211 RGD:2312338 NCBI chr10:62,241,750...62,254,145
Ensembl chr10:62,241,756...62,254,287
JBrowse link
G Si sucrase-isomaltase IEP protein:increased expression:small intestine mucosa RGD PMID:12940455 RGD:1625543 NCBI chr 2:170,220,794...170,301,348
Ensembl chr 2:170,221,245...170,301,348
JBrowse link
G Sirt1 sirtuin 1 treatment IEP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:23090186 PMID:23792339, PMID:22179968 RGD:9586012 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Slc22a1 solute carrier family 22 member 1 IDA RGD PMID:14718608 RGD:2317435 NCBI chr 1:48,273,639...48,300,645
Ensembl chr 1:48,273,611...48,300,655
JBrowse link
G Slc22a2 solute carrier family 22 member 2 IEP protein:decreased expression:kidney RGD PMID:19356064 RGD:2312728 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
G Slc28a2 solute carrier family 28 member 2 IDA RGD PMID:16014043 RGD:2317455 NCBI chr 3:114,355,003...114,647,382
Ensembl chr 3:114,355,798...114,647,382
JBrowse link
G Slc28a3 solute carrier family 28 member 3 IDA RGD PMID:16014043 RGD:2317455 NCBI chr17:6,459,024...6,509,761
Ensembl chr17:6,459,056...6,509,799
JBrowse link
G Slc29a1 solute carrier family 29 member 1 IEP mRNA:decreased expression:cardiac muscle cell RGD PMID:16873415 RGD:2316941 NCBI chr 9:17,784,468...17,799,008
Ensembl chr 9:17,784,468...17,799,005
JBrowse link
G Slc2a1 solute carrier family 2 member 1 treatment IEP mRNA, protein:decreased expression:brain RGD PMID:17935675, PMID:8345816 RGD:2313617, RGD:12879858 NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897
JBrowse link
G Slc2a2 solute carrier family 2 member 2 IEP
ISO
mRNA:increased expression:kidney
CTD Direct Evidence: marker/mechanism
CTD PMID:16123366, PMID:19433262 RGD:2312358 NCBI chr 2:114,413,427...114,445,418
Ensembl chr 2:114,413,410...114,445,395
JBrowse link
G Slc2a3 solute carrier family 2 member 3 IEP mRNA, protein:decreased expression:brain RGD PMID:17935675 RGD:2313617 NCBI chr 4:155,549,991...155,626,018
Ensembl chr 4:155,408,233...155,631,856
JBrowse link
G Slc2a4 solute carrier family 2 member 4 IEP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:11947963 PMID:14563825 PMID:18266981 PMID:22138235, PMID:19252289 RGD:2313621 NCBI chr10:56,552,921...56,558,562
Ensembl chr10:56,552,983...56,558,487
JBrowse link
G Slc37a4 solute carrier family 37 member 4 IEP protein:increased expression:liver RGD PMID:10567346 RGD:1625641 NCBI chr 8:48,716,914...48,723,024
Ensembl chr 8:48,716,939...48,723,024
JBrowse link
G Slc38a2 solute carrier family 38, member 2 IEP RGD PMID:11798158 RGD:9999213 NCBI chr 7:138,088,654...138,100,869
Ensembl chr 7:138,088,649...138,100,841
JBrowse link
G Slc8a1 solute carrier family 8 member A1 IEP mRNA, protein:decreased expression:cardiac muscle cell RGD PMID:10944172 RGD:1642714 NCBI chr 6:4,244,076...4,564,262
Ensembl chr 6:4,258,991...4,520,604
JBrowse link
G Slc9a1 solute carrier family 9 member A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20003708 NCBI chr 5:151,573,122...151,626,360
Ensembl chr 5:151,573,092...151,627,316
JBrowse link
G Slc9a3 solute carrier family 9 member A3 IDA
ISO
protein:increased activity:kidney cortex
CTD Direct Evidence: marker/mechanism
CTD PMID:20003708, PMID:16244498 RGD:1625673 NCBI chr 1:31,731,652...31,777,144
Ensembl chr 1:31,734,327...31,777,070
JBrowse link
G Smad1 SMAD family member 1 severity IEP protein:increased expression:glomerulus, urine RGD PMID:16482100 RGD:1643228 NCBI chr19:32,182,942...32,248,694
Ensembl chr19:32,188,267...32,248,684
JBrowse link
G Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 treatment IEP RGD PMID:23853776 RGD:9586347 NCBI chr 8:22,648,323...22,739,468
Ensembl chr 8:22,648,323...22,739,468
JBrowse link
G Smpd1 sphingomyelin phosphodiesterase 1 IDA protein:decreased expression:gastrocnemius RGD PMID:14983401 RGD:1601347 NCBI chr 1:170,383,682...170,387,525
Ensembl chr 1:170,383,682...170,387,524
JBrowse link
G Snap25 synaptosome associated protein 25 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16123366 NCBI chr 3:129,697,408...129,788,417
Ensembl chr 3:129,599,353...129,788,400
JBrowse link
G Soat2 sterol O-acyltransferase 2 IDA RGD PMID:15242859 RGD:1581191 NCBI chr 7:143,754,892...143,767,989
Ensembl chr 7:143,754,892...143,767,989
JBrowse link
G Socs3 suppressor of cytokine signaling 3 susceptibility IEP
ISO
mRNA, protein:increased expression:retina RGD PMID:18356406, PMID:17562326 RGD:2298911, RGD:2313787 NCBI chr10:106,973,863...106,976,969
Ensembl chr10:106,975,178...106,976,040
JBrowse link
G Sod1 superoxide dismutase 1 IEP
ISO
protein:increased expression:hippocampus (rat)
CTD Direct Evidence: marker/mechanism
CTD PMID:23090186, PMID:20924670 RGD:8655956 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 IEP
ISO
protein:increased activity:testes
CTD Direct Evidence: marker/mechanism|therapeutic
CTD PMID:15855331 PMID:23090186, PMID:19891634 RGD:2317382 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sord sorbitol dehydrogenase IEP protein:increased expression:liver RGD PMID:15064821 RGD:1601360 NCBI chr 3:114,176,127...114,207,368
Ensembl chr 3:114,176,309...114,207,366
JBrowse link
G Sox2 SRY-box transcription factor 2 IEP RGD PMID:23828673 RGD:8661677 NCBI chr 2:121,165,137...121,167,545
Ensembl chr 2:121,165,137...121,167,545
JBrowse link
G Spp1 secreted phosphoprotein 1 IDA RGD PMID:16528250 RGD:1581322 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 IEP
ISO
mRNA, protein:increased expression:renal proximal tubule, epithelial cell
CTD Direct Evidence: marker/mechanism
CTD PMID:10900012 PMID:23090186, PMID:19048273 RGD:2308804 NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009
JBrowse link
G Sstr1 somatostatin receptor 1 IEP RGD PMID:7956902 RGD:2325008 NCBI chr 6:79,252,914...79,258,611
Ensembl chr 6:79,254,339...79,258,611
JBrowse link
G Sstr2 somatostatin receptor 2 IEP RGD PMID:7956902 RGD:2325008 NCBI chr10:102,136,283...102,143,449
Ensembl chr10:102,136,283...102,143,434
JBrowse link
G Sstr3 somatostatin receptor 3 IEP RGD PMID:7956902 RGD:2325008 NCBI chr 7:119,760,881...119,768,082
Ensembl chr 7:119,760,888...119,768,082
JBrowse link
G Sstr5 somatostatin receptor 5 IEP RGD PMID:7956902 RGD:2325008 NCBI chr10:14,847,749...14,853,827
Ensembl chr10:14,847,749...14,853,827
JBrowse link
G Star steroidogenic acute regulatory protein IEP mRNA:decreased expression:sciatic nerve (rat) RGD PMID:20826654 RGD:4145530 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link
G Stat1 signal transducer and activator of transcription 1 IDA protein:increased tyrosine phosphorylation:glomerulus RGD PMID:14678947 RGD:1600105 NCBI chr 9:54,287,540...54,327,958
Ensembl chr 9:54,287,541...54,484,533
JBrowse link
G Stat3 signal transducer and activator of transcription 3 IEP
ISO
protein:increased tyrosine phosphorylation:aorta endothelium RGD PMID:18230613, PMID:22660795 RGD:2291921, RGD:8694292 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Stat4 signal transducer and activator of transcription 4 ISO RGD PMID:10553062 RGD:7207889 NCBI chr 9:54,340,649...54,457,753
Ensembl chr 9:54,287,541...54,484,533
JBrowse link
G Stat5b signal transducer and activator of transcription 5B IMP RGD PMID:17003334 RGD:2291940 NCBI chr10:88,686,207...88,712,313
Ensembl chr10:88,686,207...88,754,829
JBrowse link
G Sts steroid sulfatase ISO CTD Direct Evidence: therapeutic CTD PMID:24497646 NCBI chr  X:45,420,418...45,428,748
Ensembl chr  X:45,420,596...45,428,750
JBrowse link
G Tert telomerase reverse transcriptase IEP RGD PMID:20031167 RGD:2316310 NCBI chr 1:32,250,876...32,275,330
Ensembl chr 1:32,251,714...32,272,476
JBrowse link
G Tf transferrin IEP RGD PMID:17081048 RGD:1601532 NCBI chr 8:111,694,570...111,721,275
Ensembl chr 8:111,673,547...111,721,333
JBrowse link
G Tgfb1 transforming growth factor, beta 1 IEP
ISO
protein:increased expression:urine
CTD Direct Evidence: marker/mechanism
CTD PMID:17177138 PMID:23090186, PMID:15855808 RGD:1601583 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tgfb2 transforming growth factor, beta 2 IEP protein:increased expression:parotid gland RGD PMID:17574405 RGD:2302087 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
JBrowse link
G Th tyrosine hydroxylase IEP protein:increased expression:seminal vesicle RGD PMID:17151307 RGD:1601629 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
G Thbs1 thrombospondin 1 IMP RGD PMID:17640965 RGD:2317942 NCBI chr 3:109,862,120...109,873,466
Ensembl chr 3:109,862,117...109,873,466
JBrowse link
G Timm44 translocase of inner mitochondrial membrane 44 IEP protein:decreased expression:retina RGD PMID:23255365 RGD:13463486 NCBI chr12:2,517,006...2,533,707
Ensembl chr12:2,517,006...2,533,706
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 IEP
ISO
protein:increased expression:kidney
CTD Direct Evidence: marker/mechanism
CTD PMID:21963884, PMID:17569353, PMID:17192464 RGD:2290354, RGD:2312467 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21963884 NCBI chr10:107,338,465...107,386,072
Ensembl chr10:107,338,465...107,386,072
JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 ISO mRNA:increased expression:glomerulus RGD PMID:8840279 RGD:2312482 NCBI chr 7:23,543,125...23,594,170
Ensembl chr 7:23,544,215...23,594,133
JBrowse link
G Tjp1 tight junction protein 1 IEP protein:decreased expression:glomerulus RGD PMID:16567508 RGD:2325150 NCBI chr 1:126,146,489...126,515,359
Ensembl chr 1:126,146,489...126,227,469
JBrowse link
G Tlr2 toll-like receptor 2 IEP
ISO
RGD PMID:16740310, PMID:17707128 RGD:2312491, RGD:2312684 NCBI chr 2:182,840,171...182,846,061
Ensembl chr 2:182,840,727...182,846,061
JBrowse link
G Tlr4 toll-like receptor 4 IEP RGD PMID:16740310 RGD:2312491 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tnc tenascin C IEP RGD PMID:17999372 RGD:4889609 NCBI chr 5:79,789,686...79,874,555
Ensembl chr 5:79,789,671...79,874,671
JBrowse link
G Tnf tumor necrosis factor treatment IEP
ISO
protein:increased expression:heart
CTD Direct Evidence: marker/mechanism
protein:increased expression:liver
CTD PMID:12123627 PMID:12193562 PMID:19478208 PMID:20388520 PMID:22138235 PMID:24513509, PMID:20555424, PMID:19220660, PMID:24374093, PMID:21481476 RGD:4142788, RGD:2312478, RGD:10450575, RGD:5131250 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A IEP
ISO
protein:increased expression:liver (rat)
CTD Direct Evidence: therapeutic
CTD PMID:12193562, PMID:21481476 RGD:5131250 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B ISO human protein in rat model RGD PMID:21481476 RGD:5131250 NCBI chr 5:163,136,390...163,167,299
Ensembl chr 5:163,136,390...163,167,299
JBrowse link
G Tnfsf10 TNF superfamily member 10 ISO
IEP
RGD PMID:12577054, PMID:19572802, PMID:18649770 RGD:2312744, RGD:2312737, RGD:2312738 NCBI chr 2:113,008,008...113,026,899
Ensembl chr 2:113,007,549...113,026,899
JBrowse link
G Tomm40 translocase of outer mitochondrial membrane 40 IEP protein:decreased expression:retina RGD PMID:23255365 RGD:13463486 NCBI chr 1:80,617,749...80,630,253
Ensembl chr 1:80,618,154...80,630,038
JBrowse link
G Tomm70 translocase of outer mitochondrial membrane 70 IEP protein:decreased expression:retina RGD PMID:23255365 RGD:13463486 NCBI chr11:45,477,053...45,511,409
Ensembl chr11:45,480,250...45,510,961
JBrowse link
G Tp53 tumor protein p53 IEP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:21078376 PMID:23792339, PMID:24828139 RGD:8662307 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tp63 tumor protein p63 IEP protein:increased expression:prostate gland RGD PMID:20041964 RGD:11568648 NCBI chr11:78,234,853...78,456,559
Ensembl chr11:78,234,800...78,456,501
JBrowse link
G Tpi1 triosephosphate isomerase 1 IEP protein:decreased expression:retina RGD PMID:17465459 RGD:5147874 NCBI chr 4:157,328,375...157,331,905
Ensembl chr 4:157,328,379...157,331,905
JBrowse link
G Trex2 three prime repair exonuclease 2 IEP RGD PMID:20973890 RGD:5490977 NCBI chr  X:157,374,305...157,375,913
Ensembl chr  X:157,374,305...157,375,913
JBrowse link
G Trpc1 transient receptor potential cation channel, subfamily C, member 1 IEP mRNA:decreased expression:kidney, liver RGD PMID:18184923 RGD:2301838 NCBI chr 8:103,503,982...103,554,905
Ensembl chr 8:103,503,985...103,554,468
JBrowse link
G Tsc2 TSC complex subunit 2 IEP protein:increased threonine phosphorylation:cortex of kidney RGD PMID:18599524 RGD:8657153 NCBI chr10:13,962,006...13,996,684
Ensembl chr10:13,961,947...13,996,584
JBrowse link
G Twnk twinkle mtDNA helicase IEP
ISO
mRNA,protein:decreased expression:retina,mitochondrion: RGD PMID:22743328, PMID:22229649 RGD:8694093, RGD:8694187 NCBI chr 1:264,756,060...264,762,892
Ensembl chr 1:264,756,499...264,762,892
JBrowse link
G Txn1 thioredoxin 1 IEP mRNA:altered expression:myocardium (rat) RGD PMID:20571744 RGD:5133714 NCBI chr 5:75,049,735...75,057,731
Ensembl chr 5:75,049,747...75,057,752
JBrowse link
G Txn2 thioredoxin 2 IEP mRNA:increased expression:glomerulus
mRNA:altered expression:myocardium (rat)
RGD PMID:15039483, PMID:20571744 RGD:2306161, RGD:5133714 NCBI chr 7:119,144,350...119,158,173
Ensembl chr 7:119,144,351...119,158,201
JBrowse link
G Txnip thioredoxin interacting protein IEP protein:increased expression:kidney RGD PMID:17675577 RGD:1642749 NCBI chr 2:198,683,168...198,686,971
Ensembl chr 2:198,683,159...198,686,974
JBrowse link
G Txnrd1 thioredoxin reductase 1 IEP mRNA:altered expression:myocardium (rat) RGD PMID:20571744 RGD:5133714 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
JBrowse link
G Txnrd2 thioredoxin reductase 2 IEP mRNA:altered expression:myocardium (rat) RGD PMID:20571744 RGD:5133714 NCBI chr11:86,667,994...86,716,063
Ensembl chr11:86,667,997...86,716,254
JBrowse link
G Uba52 ubiquitin A-52 residue ribosomal protein fusion product 1 ISO mRNA:increased expression:kidney (mouse) RGD PMID:12171997 RGD:11352735 NCBI chr16:20,668,925...20,671,127
Ensembl chr16:20,668,971...20,671,127
JBrowse link
G Uchl5 ubiquitin C-terminal hydrolase L5 IEP RGD PMID:23500140 RGD:9588239 NCBI chr13:60,568,102...60,603,812
Ensembl chr13:60,545,635...60,603,811
JBrowse link
G Uck2 uridine-cytidine kinase 2 IEP protein:decreased activity:heart, skeletal muscle RGD PMID:221781 RGD:2317214 NCBI chr13:85,376,716...85,443,976
Ensembl chr13:85,376,716...85,443,976
JBrowse link
G Ucp2 uncoupling protein 2 IEP
ISO
protein:increased expression:kidney
CTD Direct Evidence: marker/mechanism
CTD PMID:14563825 PMID:16123366, PMID:19227473 RGD:2313501 NCBI chr 1:165,506,375...165,512,744
Ensembl chr 1:165,506,361...165,512,744
JBrowse link
G Ucp3 uncoupling protein 3 susceptibility IEP
ISO
mRNA:increased expression:skeletal muscle RGD PMID:10868941, PMID:12079841 RGD:2313524, RGD:2313520 NCBI chr 1:165,482,912...165,495,895
Ensembl chr 1:165,482,155...165,496,206
JBrowse link
G Ugt2b17 UDP glucuronosyltransferase family 2 member B17 IEP mRNA:increased expression:liver RGD PMID:20487213 RGD:11541075 NCBI chr14:22,724,399...22,736,148
Ensembl chr14:22,724,070...22,825,444
JBrowse link
G Umod uromodulin IEP protein:increased expression:urine RGD PMID:10925066 RGD:2324705 NCBI chr 1:189,186,027...189,199,939
Ensembl chr 1:189,186,026...189,199,376
JBrowse link
G Umps uridine monophosphate synthetase IEP protein:decreased activity:liver (rat)
protein:decreased activity:mammary gland (rat)
RGD PMID:3907307, PMID:1476792 RGD:5132278, RGD:5132591 NCBI chr11:70,034,181...70,044,590
Ensembl chr11:70,034,139...70,044,628
JBrowse link
G Uprt uracil phosphoribosyltransferase homolog IEP protein:decreased activity:mammary gland (rat) RGD PMID:1476792 RGD:5132591 NCBI chr  X:75,382,553...75,408,541
Ensembl chr  X:75,382,598...75,407,217
JBrowse link
G Uts2r urotensin 2 receptor IMP RGD PMID:16267137 RGD:2306839 NCBI chr10:110,364,291...110,365,451
Ensembl chr10:110,364,291...110,365,451
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 IEP
ISO
mRNA, protein:increased expression:kidney
mRNA:increased expression:aorta
RGD PMID:18983856, PMID:18093596 RGD:2312764, RGD:2306988 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
JBrowse link
G Vdac1 voltage-dependent anion channel 1 IEP protein:increased expression:kidney RGD PMID:19634143 RGD:10003054 NCBI chr10:37,724,915...37,752,827
Ensembl chr10:37,724,915...37,752,826
JBrowse link
G Vegfa vascular endothelial growth factor A IEP
ISO
IDA
mRNA:decreased expression:heart
CTD Direct Evidence: marker/mechanism
mRNA:decreased expression:skeletal muscle
CTD PMID:22191573, PMID:16741021, PMID:19934008, PMID:16816123 RGD:2313724, RGD:7421582, RGD:2313725 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Vegfb vascular endothelial growth factor B ISO mRNA:decreased expression:skeletal muscle RGD PMID:16816123 RGD:2313725 NCBI chr 1:222,237,000...222,242,786
Ensembl chr 1:222,239,022...222,242,644
JBrowse link
G Vip vasoactive intestinal peptide ISO RGD PMID:21129425 RGD:5685622 NCBI chr 1:42,169,307...42,177,582
Ensembl chr 1:42,169,501...42,177,582
JBrowse link
G Vipr1 vasoactive intestinal peptide receptor 1 ISO RGD PMID:21129425 RGD:5685622 NCBI chr 8:130,283,453...130,313,431 JBrowse link
G Vldlr very low density lipoprotein receptor IEP protein:decreased expression:heart, skeletal muscle RGD PMID:15878964 RGD:1625575 NCBI chr 1:245,236,819...245,273,688
Ensembl chr 1:245,237,736...245,269,205
JBrowse link
G Vwf von Willebrand factor IEP protein:increased expression:plasma RGD PMID:17546272 RGD:1625712 NCBI chr 4:158,085,059...158,219,525
Ensembl chr 4:158,088,505...158,219,523
JBrowse link
G Wdr35 WD repeat domain 35 IEP mRNA:increased expression:kidney (rat) RGD PMID:20224876 RGD:11553923 NCBI chr 6:34,094,291...34,152,048
Ensembl chr 6:34,094,306...34,151,622
JBrowse link
G Xdh xanthine dehydrogenase IEP protein:increased expression:brain, heart, kidney RGD PMID:14532905 RGD:1304441 NCBI chr 6:25,149,570...25,211,273
Ensembl chr 6:25,149,235...25,211,494
JBrowse link
G Ywhah tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta ISO CTD Direct Evidence: therapeutic CTD PMID:18342293 NCBI chr14:83,053,041...83,062,424
Ensembl chr14:83,053,041...83,062,424
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16123
    Animal Diseases 1645
      Animal Disease Models 1601
        Experimental Diabetes Mellitus 589
Path 2
Term Annotations click to browse term
  disease 16123
    Nutritional and Metabolic Diseases 4712
      disease of metabolism 4712
        acquired metabolic disease 2760
          carbohydrate metabolism disease 1764
            glucose metabolism disease 0
              diabetes mellitus 1373
                Experimental Diabetes Mellitus 589
paths to the root