Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Experimental Diabetes Mellitus
go back to main search page
Accession:DOID:9005643 term browser browse the term
Definition:Diabetes mellitus induced experimentally by administration of various diabetogenic agents or by PANCREATECTOMY.
Synonyms:exact_synonym: Alloxan Diabetes;   Experimental Diabetes Mellitus;   Streptozocin Diabete;   streptozocin diabetes;   streptozotocin diabetes
 primary_id: MESH:D003921
For additional species annotation, visit the Alliance of Genome Resources.



show annotations for term's descendants           Sort by:
 
Experimental Diabetes Mellitus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aacs acetoacetyl-CoA synthetase IDA protein:decreased activity:liver RGD PMID:12034369 RGD:2301022 NCBI chr12:31,113,098...31,156,411
Ensembl chr12:31,113,098...31,160,954
JBrowse link
G Aanat aralkylamine N-acetyltransferase IEP RGD PMID:18624957 RGD:2301030 NCBI chr10:101,827,072...101,831,805
Ensembl chr10:101,827,301...101,831,801
JBrowse link
G Abat 4-aminobutyrate aminotransferase IDA RGD PMID:9846053 RGD:1598518 NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A disease_progression
treatment
IAGP
IEP
IDA
protein: decreased expression
mRNA:increased expression:brain
mRNA:increased expression:ileum, intestinal mucosa (rat)
RGD PMID:17074306 PMID:17664251 PMID:26460146 PMID:21685928 RGD:1598559, RGD:2312730, RGD:11041112, RGD:8657121 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B disease_progression IDA
IEP
mRNA:increased expression:brain
mRNA:increased expression:ileum, intestinal mucosa (rat)
RGD PMID:17074306 PMID:17664251 PMID:26460146 RGD:1598559, RGD:2312730, RGD:11041112 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 IDA RGD PMID:12055592 RGD:1598588 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 IEP protein: increased expression
mRNA:decreased expression:liver
mRNA: increased expression: brain
RGD PMID:19356064 PMID:20487213 PMID:17664251 RGD:2312728, RGD:11541075, RGD:2312730 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 IEP mRNA:increased expression:liver RGD PMID:20487213 RGD:11541075 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Abcc9 ATP binding cassette subfamily C member 9 IEP mRNA, protein:decreased expression:heart RGD PMID:22257425 RGD:12792003 NCBI chr 4:175,531,854...175,655,849
Ensembl chr 4:175,532,547...175,655,356
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 IEP protein:decreased expression:cerebral cortex RGD PMID:17915193 RGD:2315584 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 IEP RGD PMID:14618236 RGD:1558629 NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563
JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 IEP RGD PMID:14618236 RGD:1558629 NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:9,945,629...9,964,912
JBrowse link
G Acaa1a acetyl-CoA acyltransferase 1A IEP mRNA:increased expression:heart RGD PMID:17632588 RGD:2313044 NCBI chr 8:119,079,401...119,088,624
Ensembl chr 8:119,079,775...119,088,624
JBrowse link
G Acadvl acyl-CoA dehydrogenase, very long chain ISO protein:decreased expression:brain RGD PMID:25260493 RGD:10047114 NCBI chr10:54,732,875...54,738,102
Ensembl chr10:54,732,469...54,738,075
JBrowse link
G Ace angiotensin I converting enzyme IEP
ISO
protein:increased expression:kidney
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:22191573 PMID:18679036 RGD:2313799 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Ace2 angiotensin I converting enzyme 2 IEP protein:altered expression:kidney RGD PMID:18679036 RGD:2313799 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977
JBrowse link
G Ache acetylcholinesterase treatment IEP
IDA
protein:increased expression:blood RGD PMID:1385785 PMID:19347982 PMID:19296211 PMID:19303406 RGD:2312437, RGD:150517552, RGD:2312432, RGD:2312430 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Acmsd aminocarboxymuconate semialdehyde decarboxylase treatment IDA
IEP
RGD PMID:12042425 PMID:19169727 RGD:13831125, RGD:13831126 NCBI chr13:39,200,486...39,244,337
Ensembl chr13:39,200,314...39,245,209
JBrowse link
G Acot1 acyl-CoA thioesterase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14563825 NCBI chr 6:103,636,173...103,644,167
Ensembl chr 6:103,636,041...103,644,163
JBrowse link
G Acot2 acyl-CoA thioesterase 2 IEP protein:increased expression:heart, mitochondrion (rat) RGD PMID:17438340 RGD:2315861 NCBI chr 6:103,611,744...103,619,404
Ensembl chr 6:103,611,544...103,619,245
JBrowse link
G Acox1 acyl-CoA oxidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14563825 NCBI chr10:101,406,197...101,431,242
Ensembl chr10:101,406,197...101,431,232
JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant IEP protein:increased activity:femoral bone (rat) RGD PMID:19699734 RGD:2315882 NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:20,663,985...20,667,929
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:9452481 NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 IEP RGD PMID:21136146 RGD:13831298 NCBI chr 9:80,140,996...80,164,636
Ensembl chr 9:80,115,112...80,164,627
JBrowse link
G Acsl6 acyl-CoA synthetase long-chain family member 6 IEP mRNA:decreased expression:heart RGD PMID:16428347 RGD:1599808 NCBI chr10:38,439,914...38,501,182
Ensembl chr10:38,440,080...38,498,757
JBrowse link
G Ada adenosine deaminase IEP
ISO
protein:increased expression:platelet RGD PMID:19166862 PMID:9784839 RGD:2313538, RGD:2313540 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088
JBrowse link
G Adcyap1 adenylate cyclase activating polypeptide 1 IEP protein:increased expression:pancreas, hypothalamus RGD PMID:9864055 RGD:2325314 NCBI chr 9:113,102,632...113,122,500
Ensembl chr 9:113,103,718...113,109,773
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing IEP
ISO
mRNA, protein:decreased expression:adipose tissue, serum
protein:increased expression:retina
RGD PMID:16201273 PMID:23174569 RGD:1599146, RGD:8694416 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Adipor2 adiponectin receptor 2 no_association IDA
ISO
RGD PMID:17884446 PMID:19220660 PMID:18222103 RGD:2312495, RGD:2312478, RGD:2312488 NCBI chr 4:152,524,604...152,588,848
Ensembl chr 4:152,524,623...152,559,355
JBrowse link
G Adk adenosine kinase IEP protein:decreased expression:spleen, lymphocyte RGD PMID:12729803 RGD:2313360 NCBI chr15:2,863,241...3,246,453
Ensembl chr15:2,863,244...3,246,510
JBrowse link
G Adm adrenomedullin IEP protein:increased expression:pigmented epithelial cell, retina RGD PMID:16955796 RGD:1625296 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
JBrowse link
G Adora1 adenosine A1 receptor treatment IDA
ISO
IEP
associated with hypertension
protein:decreased expression:hippocampus
RGD PMID:11593763 PMID:9597368 PMID:19276628 PMID:16256246 RGD:2313808, RGD:1625365, RGD:2313804, RGD:2313805 NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801
JBrowse link
G Adora2a adenosine A2a receptor IEP protein:increased expression:hippocampus RGD PMID:16256246 RGD:2313805 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386
JBrowse link
G Adra1a adrenoceptor alpha 1A IEP
ISO
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:19133277 PMID:17054657 RGD:1625775 NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500
JBrowse link
G Adrb1 adrenoceptor beta 1 IEP protein:decreased expression:left ventricle muscular part RGD PMID:21054861 RGD:5129115 NCBI chr 1:255,772,217...255,773,617
Ensembl chr 1:255,771,597...255,807,259
JBrowse link
G Adrb3 adrenoceptor beta 3 IEP
ISO
protein:increased expression:left ventricle muscular part
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:17622774 PMID:21054861 RGD:5129115 NCBI chr16:64,839,820...64,844,552
Ensembl chr16:64,841,788...64,844,552
JBrowse link
G Adsl adenylosuccinate lyase IEP protein:increased activity:heart (rat) RGD PMID:3360219 RGD:1598762 NCBI chr 7:112,479,256...112,503,439
Ensembl chr 7:112,479,271...112,503,760
JBrowse link
G Adss1 adenylosuccinate synthase 1 IEP protein:increased activity:heart (rat) RGD PMID:3360219 RGD:1598762 NCBI chr 6:131,679,795...131,702,012
Ensembl chr 6:131,679,701...131,701,998
JBrowse link
G Ager advanced glycosylation end product-specific receptor treatment IEP
IDA
ISO
protein:increased expression:lacrimal gland
mRNA:increased expression:renal cortex (mouse)
RGD PMID:16283249 PMID:22476978 PMID:21458563 PMID:20801062 RGD:1625335, RGD:7245558, RGD:7244188, RGD:7243964 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
JBrowse link
G Agt angiotensinogen ISO CTD Direct Evidence: marker/mechanism CTD PMID:15831366 PMID:17177138 PMID:18829990 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Agtr2 angiotensin II receptor, type 2 IEP mRNA, protein:decreased expression:kidney RGD PMID:12172324 RGD:6903861 NCBI chr  X:112,119,673...112,124,060
Ensembl chr  X:112,120,228...112,124,057
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23499715 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256
JBrowse link
G Aire autoimmune regulator susceptibility ISO RGD PMID:18399912 RGD:2306853 NCBI chr20:10,636,058...10,651,060
Ensembl chr20:10,636,123...10,651,060
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B IEP mRNA:increased expression:kidney (rat) RGD PMID:8204669 RGD:8548781 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
JBrowse link
G Akt1 AKT serine/threonine kinase 1 IDA
IEP
protein:decreased serine phosphorylation:cornea
protein:increased serine phosphorylation:cortex of kidney
RGD PMID:21330660 PMID:18599524 RGD:5131482, RGD:8657153 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Alad aminolevulinate dehydratase susceptibility
treatment
IEP
IDA
ISO
protein:decreased activity:liver, kidney (rat)
protein:decreased activity:liver, erythrocyte (rat)
protein:decreased activity:blood, liver
RGD PMID:19043199 PMID:10224671 PMID:18668330 PMID:21864646 PMID:24947461 More... RGD:4144150, RGD:15039405, RGD:12904704, RGD:12904702, RGD:12904692, RGD:12904683 NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474
JBrowse link
G Alas1 5'-aminolevulinate synthase 1 IEP protein:decreased activity:liver (rat) RGD PMID:6688350 RGD:4144808 NCBI chr 8:106,876,514...106,889,852
Ensembl chr 8:106,876,514...106,889,917
JBrowse link
G Aldob aldolase, fructose-bisphosphate B IEP mRNA:reduced expression:liver, small intestine (rat) RGD PMID:2984252 RGD:2313437 NCBI chr 5:63,889,045...63,902,086
Ensembl chr 5:63,889,046...63,902,116
JBrowse link
G Andpro androgen regulated protein IEP protein:decreased expression:corpus cavernosum penis (rat) RGD PMID:20007950 RGD:14696816 NCBI chr 3:136,718,601...136,725,131
Ensembl chr 3:136,718,602...136,724,966
JBrowse link
G Angpt1 angiopoietin 1 IEP protein:increased expression:retina RGD PMID:15047628 PMID:17294737 RGD:2313817, RGD:1626163 NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067
JBrowse link
G Angpt2 angiopoietin 2 IEP protein:increased expression:retina RGD PMID:15047628 RGD:2313817 NCBI chr16:71,088,364...71,138,805
Ensembl chr16:71,088,364...71,138,804
JBrowse link
G Angptl3 angiopoietin-like 3 ISO protein:increased expression:liver RGD PMID:15094378 RGD:2314234 NCBI chr 5:113,703,007...113,710,044
Ensembl chr 5:113,703,012...113,709,957
JBrowse link
G Anxa1 annexin A1 IEP protein:increased glycation:respiratory system blood vessel endothelium RGD PMID:11423489 RGD:2306888 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
JBrowse link
G Anxa2 annexin A2 IEP protein:increased glycation:respiratory system blood vessel endothelium RGD PMID:11423489 RGD:2306888 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
JBrowse link
G Aoc1 amine oxidase, copper containing 1 IEP RGD PMID:1632778 RGD:2312809 NCBI chr 4:77,812,260...77,831,846
Ensembl chr 4:77,812,260...77,831,840
JBrowse link
G Aoc3 amine oxidase, copper containing 3 ISO
IEP
IMP
CTD Direct Evidence: marker/mechanism
protein:increased expression:kidney, serum
CTD
RGD
PMID:14977883 PMID:12606817 PMID:2218072 PMID:19635478 RGD:2313824, RGD:2313828, RGD:2313819 NCBI chr10:86,272,757...86,280,702 JBrowse link
G Apoa1 apolipoprotein A1 treatment IDA RGD PMID:17488882 RGD:7241577 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Apob apolipoprotein B IEP RGD PMID:17292734 RGD:1642185 NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
JBrowse link
G Apoe apolipoprotein E IEP protein:decreased expression:plasma (rat) RGD PMID:16947119 RGD:1599198 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Apom apolipoprotein M ISO protein:decreased secretion:plasma RGD PMID:16516154 RGD:2314249 NCBI chr20:3,690,950...3,693,550
Ensembl chr20:3,688,413...3,693,550
JBrowse link
G Aprt adenine phosphoribosyl transferase IEP protein:decreased activity:mammary gland (rat) RGD PMID:2451510 RGD:1599204 NCBI chr19:50,626,436...50,628,404
Ensembl chr19:50,626,202...50,628,431
JBrowse link
G Aqp1 aquaporin 1 IEP protein:increased expression:retina RGD PMID:19596320 RGD:2316078 NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690
JBrowse link
G Aqp2 aquaporin 2 IEP
ISO
protein:increased expression:Kidney Medulla
protein:decreased expression:kidney collecting duct
RGD PMID:11380083 PMID:15705184 RGD:2314347, RGD:2314326 NCBI chr 7:130,711,433...130,716,468
Ensembl chr 7:130,711,413...130,716,468
JBrowse link
G Aqp4 aquaporin 4 IEP mRNA,protein:increased expression:retina: RGD PMID:22449442 RGD:8695996 NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856
JBrowse link
G Ar androgen receptor ISO
IEP
protein:decreased expression:pancreatic B cell
mRNA, protein:decreased expression:epididymis, prostate gland, testis
RGD PMID:18543106 PMID:16398356 RGD:2306772, RGD:2306774 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Arg1 arginase 1 IEP protein:increased expression:aorta, liver (rat) RGD PMID:17967788 RGD:4142848 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
JBrowse link
G Arg2 arginase 2 IEP protein:increased activity:kidney (rat) RGD PMID:12841630 RGD:4143269 NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378
JBrowse link
G Arntl aryl hydrocarbon receptor nuclear translocator-like IEP RGD PMID:18624957 RGD:2301030 NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231
JBrowse link
G Aspa aspartoacylase ISO protein:increased expression:duodenum, brain RGD PMID:16707098 RGD:1601247 NCBI chr10:57,891,704...57,945,267
Ensembl chr10:57,892,104...57,945,272
JBrowse link
G Ass1 argininosuccinate synthase 1 IEP mRNA, protein:increased expression:aorta (rat) RGD PMID:11384198 RGD:1599310 NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903
JBrowse link
G Atf3 activating transcription factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16123366 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Atg7 autophagy related 7 treatment ISO
IEP
protein:decreased expression:myocardium RGD PMID:24874076 PMID:24993523 RGD:11557993, RGD:11557996 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593
JBrowse link
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 IEP RGD PMID:28483572 RGD:12910731 NCBI chr 1:181,026,606...181,044,859
Ensembl chr 1:181,026,608...181,044,838
JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 IDA
IEP
ISO
protein:increased carbonylation:heart
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:16123366 PMID:21300842 PMID:20122173 PMID:28483572 RGD:6904139, RGD:13782130, RGD:12910731 NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101
JBrowse link
G Atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 ISO
IEP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:16123366 PMID:20122173 RGD:13782130 NCBI chr10:57,581,742...57,612,758
Ensembl chr10:57,582,128...57,612,748
JBrowse link
G Atp4b ATPase H+/K+ transporting subunit beta IEP RGD PMID:20237950 RGD:14696743 NCBI chr16:76,144,150...76,153,063
Ensembl chr16:76,144,150...76,153,063
JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha IEP protein:decreased expression:cerebral cortex, mitochondrion (rat) RGD PMID:28526935 RGD:13703047 NCBI chr18:71,292,406...71,300,342
Ensembl chr18:71,292,374...71,300,794
JBrowse link
G Atp5f1b ATP synthase F1 subunit beta IEP associated with polycystic ovary syndrome;mRNA, protein:decreased expression:pancreas (rat) RGD PMID:28397049 RGD:13703107 NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273
JBrowse link
G Atp5pd ATP synthase peripheral stalk subunit d IEP protein:decreased expression:retina (rat) RGD PMID:17465459 RGD:5147874 NCBI chr10:100,657,700...100,662,960
Ensembl chr10:100,657,708...100,663,479
JBrowse link
G Atp5pf ATP synthase peripheral stalk subunit F6 treatment IEP RGD PMID:28731155 RGD:13800891 NCBI chr11:23,881,594...23,889,581
Ensembl chr11:23,881,592...23,889,119
JBrowse link
G Avp arginine vasopressin ISO mRNA:increased expression:hypothalamus RGD PMID:18420743 RGD:2301919 NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425
JBrowse link
G Bad BCL2-associated agonist of cell death IDA protein:increased expression, decreased phosphorylation, altered activity:testis
protein:decreased serine phosphorylation:cornea
RGD PMID:17870134 PMID:21330660 RGD:2292685, RGD:5131482 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bax BCL2 associated X, apoptosis regulator treatment IEP
ISO
protein:increased expression:retina
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:23090186 PMID:18991018 PMID:23267840 RGD:2311240, RGD:10054099 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bche butyrylcholinesterase IDA protein:decreased expression:retina RGD PMID:11478742 PMID:12379509 PMID:16187484 RGD:2306783, RGD:2306781, RGD:1599458 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
JBrowse link
G Bckdha branched chain keto acid dehydrogenase E1 subunit alpha IEP protein:increased expression:liver RGD PMID:9460082 RGD:1599467 NCBI chr 1:81,138,946...81,167,765
Ensembl chr 1:81,138,947...81,167,862
JBrowse link
G Bckdhb branched chain keto acid dehydrogenase E1 subunit beta IEP Protein:increased expression:liver; RGD PMID:9460082 RGD:1599467 NCBI chr 8:84,845,264...85,027,812
Ensembl chr 8:84,845,264...85,027,812
JBrowse link
G Bcl2 BCL2, apoptosis regulator IEP
ISO
protein:increased expression:retina
CTD Direct Evidence: marker/mechanism
mRNA:decreased expression:embryo
CTD
RGD
PMID:16959961 PMID:23090186 PMID:18991018 PMID:15649569 RGD:2311240, RGD:1599491 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 IDA
ISO
protein:decreased expression, altered activity:testis
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:16959961 PMID:17870134 RGD:2292685 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bdh1 3-hydroxybutyrate dehydrogenase 1 IEP protein:decreased activity:heart, mitochondrion (rat) RGD PMID:3548709 RGD:2326100 NCBI chr11:69,302,534...69,343,173
Ensembl chr11:69,302,534...69,337,671
JBrowse link
G Bdkrb1 bradykinin receptor B1 IEP
ISO
IDA
mRNA:increased expression:heart
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:21430409 PMID:12489796 PMID:20092893 PMID:12522068 RGD:704379, RGD:7241569, RGD:704380 NCBI chr 6:124,510,827...124,514,475
Ensembl chr 6:124,510,870...124,513,747
JBrowse link
G Bdkrb2 bradykinin receptor B2 IEP protein:increased expression:hindbrain, spinal cord
mRNA:increased expression:heart
RGD PMID:16138314 PMID:12489796 RGD:4890452, RGD:704379 NCBI chr 6:124,472,317...124,502,497
Ensembl chr 6:124,472,566...124,502,497
JBrowse link
G Bdnf brain-derived neurotrophic factor treatment IEP RGD PMID:24857910 RGD:10059399 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Becn1 beclin 1 treatment IEP RGD PMID:24993523 RGD:11557996 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Bglap bone gamma-carboxyglutamate protein IEP protein:reduced expression:serum (rat) RGD PMID:19494718 RGD:2316184 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 IEP protein:increased expression:lung RGD PMID:21521772 RGD:5135278 NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809
JBrowse link
G Btc betacellulin ISO RGD PMID:14988244 PMID:19819964 PMID:18388935 RGD:1357906, RGD:2313774, RGD:2306965 NCBI chr14:16,708,447...16,746,961
Ensembl chr14:16,707,982...16,747,049
JBrowse link
G Cacng4 calcium voltage-gated channel auxiliary subunit gamma 4 IEP mRNA:decreased expression:sinoatrial node: RGD PMID:27096430 RGD:13524560 NCBI chr10:92,686,100...92,745,601
Ensembl chr10:92,683,761...92,746,126
JBrowse link
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase IEP protein:decreased activity:mammary gland (rat) RGD PMID:1476792 RGD:5132591 NCBI chr 6:25,292,133...25,315,176
Ensembl chr 6:25,292,133...25,319,861
JBrowse link
G Calca calcitonin-related polypeptide alpha IEP protein:increased expression:penis erectile tissue, seminal vesicle
protein:decreased expression:dorsal root ganglion, neuron
RGD PMID:19152794 PMID:17151309 RGD:2314033, RGD:2314035 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
JBrowse link
G Cald1 caldesmon 1 IEP RGD PMID:10644879 RGD:2314036 NCBI chr 4:63,265,781...63,446,936
Ensembl chr 4:63,265,942...63,446,932
JBrowse link
G Capn10 calpain 10 IEP mRNA, protein:decreased expression:kidney cortex RGD PMID:22568896 RGD:7247732 NCBI chr 9:93,498,132...93,510,494
Ensembl chr 9:93,498,478...93,510,494
JBrowse link
G Carhsp1 calcium regulated heat stable protein 1 treatment IEP RGD PMID:19997081 RGD:39128203 NCBI chr10:6,946,036...6,960,556
Ensembl chr10:6,946,959...7,020,019
JBrowse link
G Casp1 caspase 1 IEP mRNA:increased expression:retina RGD PMID:18398369 RGD:2315888 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp3 caspase 3 treatment IEP
ISO
protein:increased activity:hypothalamus
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:20654064 PMID:19094082 PMID:28843149 RGD:2311447, RGD:13782300 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp6 caspase 6 IDA protein:increased activity:heart left ventricle RGD PMID:15662549 RGD:2301316 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502
JBrowse link
G Casp8 caspase 8 treatment ISO
IEP
protein:increased expression, increased activity:pituitary gland
protein:increased activity, increased expression:pituitary gland, prolactin secreting cell
RGD PMID:17563067 PMID:28843149 PMID:19540304 PMID:15976052 RGD:2311429, RGD:13782300, RGD:2311427, RGD:2311319 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 IEP protein:increased activity, increased expression:pituitary gland RGD PMID:15976052 RGD:2311319 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Casq1 calsequestrin 1 IEP protein:increased activity:skeletal muscle tissue RGD PMID:11976916 RGD:2314137 NCBI chr13:84,670,648...84,680,339
Ensembl chr13:84,670,649...84,680,339
JBrowse link
G Casr calcium-sensing receptor IEP protein:increased expression:pancreas, liver, kidney (rat) RGD PMID:22844268 RGD:7205442 NCBI chr11:64,235,251...64,304,811
Ensembl chr11:64,235,251...64,304,811
JBrowse link
G Cat catalase IEP
ISO
CTD Direct Evidence: marker/mechanism|therapeutic CTD
RGD
PMID:12123627 PMID:15855331 PMID:20709041 PMID:20376213 RGD:5130772 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cav1 caveolin 1 IEP
ISO
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:18266981 PMID:25086377 RGD:10045572 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Cav3 caveolin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18266981 NCBI chr 4:145,582,168...145,598,142
Ensembl chr 4:145,582,060...145,598,137
JBrowse link
G Cbr1 carbonyl reductase 1 IEP protein:decreased expression:pancreas (rat) RGD PMID:18452227 RGD:2302233 NCBI chr11:32,860,618...32,862,981
Ensembl chr11:32,857,991...32,895,275
JBrowse link
G Cck cholecystokinin IDA RGD PMID:15536283 RGD:2313638 NCBI chr 8:121,153,499...121,160,194
Ensembl chr 8:121,153,500...121,160,084
JBrowse link
G Cckbr cholecystokinin B receptor IEP mRNA, protein:decreased expression:pancreas RGD PMID:15161757 RGD:1358452 NCBI chr 1:159,771,733...159,781,738
Ensembl chr 1:159,771,733...159,814,881
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 treatment IEP
IDA
protein:increased expression:gingiva
protein:increased expression:plasma
RGD PMID:17876613 PMID:16891764 PMID:18976114 RGD:2306992, RGD:8549535, RGD:2306984 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl20 C-C motif chemokine ligand 20 ISO CTD Direct Evidence: therapeutic CTD PMID:21340626 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629
JBrowse link
G Ccn2 cellular communication network factor 2 IEP mRNA, protein:increased expression:heart, myocardium (rat) RGD PMID:19820199 RGD:2314021 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
JBrowse link
G Ccna2 cyclin A2 IEP RGD PMID:20031167 RGD:2316310 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnb1 cyclin B1 IEP mRNA:decreased expression:liver (rat) RGD PMID:20031167 RGD:2316310 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnd3 cyclin D3 IEP protein:increased expression:kidney, glomerulus RGD PMID:19276076 RGD:2316018 NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371
JBrowse link
G Ccnt1 cyclin T1 IEP mRNA,protein:decreased expression:liver: RGD PMID:20828602 RGD:9698426 NCBI chr 7:129,687,146...129,718,082
Ensembl chr 7:129,691,209...129,717,871
JBrowse link
G Ccr5 C-C motif chemokine receptor 5 IEP protein:increased expression:retina RGD PMID:21575160 RGD:11533943 NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260
JBrowse link
G Cd28 Cd28 molecule ISO RGD PMID:11160314 RGD:2307200 NCBI chr 9:62,166,324...62,194,674
Ensembl chr 9:62,166,192...62,194,685
JBrowse link
G Cd36 CD36 molecule treatment IEP mRNA:increased expression:multiple organs RGD PMID:16838191 PMID:23691525 RGD:2307214, RGD:11041145 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
JBrowse link
G Cd3e CD3e molecule ISO RGD PMID:16628253 RGD:2314179 NCBI chr 8:45,303,848...45,315,297
Ensembl chr 8:45,303,852...45,315,022
JBrowse link
G Cd40lg CD40 ligand treatment ISO
IEP
protein:increased expression:platelet (rat) RGD PMID:21831422 PMID:19237211 RGD:11352661, RGD:2312338 NCBI chr  X:135,127,119...135,138,302
Ensembl chr  X:135,126,969...135,138,306
JBrowse link
G Cd68 Cd68 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:20388520 NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697
JBrowse link
G Cd80 Cd80 molecule ISO RGD PMID:11160314 RGD:2307200 NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030
JBrowse link
G Cd86 CD86 molecule ISO RGD PMID:8993020 RGD:2313930 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
JBrowse link
G Cdk9 cyclin-dependent kinase 9 IEP mRNA,protein:decreased expression:liver: RGD PMID:20828602 RGD:9698426 NCBI chr 3:15,996,467...16,001,315
Ensembl chr 3:15,996,468...16,002,410
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A IEP protein:increased expression:testes: RGD PMID:24828139 RGD:8662307 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cel carboxyl ester lipase IEP protein:decreased expression:pancreas, RGD PMID:8446851 RGD:2313971 NCBI chr 3:11,883,532...11,891,035
Ensembl chr 3:11,883,532...11,891,035
JBrowse link
G Cfd complement factor D IEP protein:decreased expression:serum RGD PMID:8372111 RGD:1624344 NCBI chr 7:9,813,148...9,814,871
Ensembl chr 7:9,813,150...9,815,053
JBrowse link
G Cftr CF transmembrane conductance regulator severity ISO RGD PMID:16804061 RGD:2314614 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18603373 NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103
JBrowse link
G Clps colipase IEP RGD PMID:19577003 RGD:2314624 NCBI chr20:6,620,529...6,622,709
Ensembl chr20:6,620,529...6,622,689
JBrowse link
G Clu clusterin IEP protein:increased expression:retina
protein:increased expression:pancreatic islet
RGD PMID:12763621 PMID:23351716 RGD:9068392, RGD:9068411 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
JBrowse link
G Cma1 chymase 1 IEP protein:increased expression:mesenteric artery, mast cell (rat) RGD PMID:15337505 RGD:5128799 NCBI chr15:29,417,451...29,420,233
Ensembl chr15:29,417,451...29,420,233
JBrowse link
G Cnr1 cannabinoid receptor 1 IEP protein:increased expression:hypothalamus, striatum RGD PMID:18401837 RGD:2314633 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
JBrowse link
G Comt catechol-O-methyltransferase IDA protein:decreased expression:liver RGD PMID:12010186 RGD:2289789 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
G Cp ceruloplasmin IEP Protein:increased expression:plasma RGD PMID:16947119 RGD:1599198 NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075
JBrowse link
G Cps1 carbamoyl-phosphate synthase 1 IEP protein:increased activity:liver (rat) RGD PMID:2882780 RGD:4144110 NCBI chr 9:68,614,153...68,737,037
Ensembl chr 9:68,614,153...68,737,033
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:16123366 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:14563825 NCBI chr 7:120,491,354...120,500,833
Ensembl chr 7:120,491,354...120,500,404
JBrowse link
G Crh corticotropin releasing hormone IEP mRNA:increased expression:paraventricular hypothalamic nucleus (rat) RGD PMID:9652969 RGD:5508166 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
JBrowse link
G Crp C-reactive protein IDA
ISO
RGD PMID:21736771 PMID:21736794 RGD:6482316, RGD:6907422 NCBI chr13:85,131,635...85,175,179
Ensembl chr13:85,124,977...85,175,178
JBrowse link
G Crtc2 CREB regulated transcription coactivator 2 IMP RGD PMID:23595987 RGD:9685169 NCBI chr 2:175,709,603...175,719,768
Ensembl chr 2:175,709,644...175,719,763
JBrowse link
G Ctsb cathepsin B IEP protein:decreased activity:glomerulus (rat) RGD PMID:10393385 RGD:2315531 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
JBrowse link
G Ctsc cathepsin C IEP RGD PMID:148980 RGD:1599652 NCBI chr 1:142,028,386...142,059,841
Ensembl chr 1:142,028,392...142,060,387
JBrowse link
G Ctsl cathepsin L IEP mRNA:increased expression:gastrocnemius muscle (rat) RGD PMID:14718385 RGD:1641826 NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 IEP
ISO
mRNA:increased expression:kidney
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:20388520 PMID:15153757 RGD:4891992 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833
JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 IEP mRNA:increased expression:kidney RGD PMID:15153757 RGD:4891992 NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 ISO mRNA:increased expression:pancreatic islet RGD PMID:17372021 RGD:2311360 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 IEP
ISO
protein:increased expression:retina RGD PMID:18201529 PMID:17878289 RGD:2306555, RGD:2306557 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
JBrowse link
G Cyba cytochrome b-245 alpha chain IEP
ISO
mRNA, protein:increased expression:aorta
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:pancreas:
CTD
RGD
PMID:11812764 PMID:12967931 PMID:20226688 PMID:23905384 RGD:2317852, RGD:11040693 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
JBrowse link
G Cybb cytochrome b-245 beta chain IEP
ISO
mRNA:increased expression:aorta
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:cerebral cortex;associated with reperfusion injury
CTD
RGD
PMID:19478208 PMID:11157681 PMID:15148062 RGD:1599691, RGD:1599683 NCBI chr  X:13,360,583...13,392,517
Ensembl chr  X:13,359,430...13,392,586
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 IEP mRNA:decreased expression:sciatic nerve (rat) RGD PMID:20826654 RGD:4145530 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 IEP mRNA:increased expression:kidney RGD PMID:18582458 RGD:2307289 NCBI chr 7:106,838,590...106,845,004
Ensembl chr 7:106,838,590...106,845,004
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 IEP protein:decreased expression:ovary, testis (rat) RGD PMID:20428845 RGD:4890359 NCBI chr 8:54,553,165...54,580,758
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 IDA
ISO
protein:increased expression:liver, microsome (rat)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:22342832 PMID:10711628 RGD:2307074 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 IDA RGD PMID:3295473 RGD:2307313 NCBI chr 7:62,869,340...62,876,242
Ensembl chr 7:62,871,297...62,876,241
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 IEP
ISO
protein:increased expression:liver
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:22342832 PMID:17015271 RGD:2301459 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 ISO mRNA:increased expression:liver
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:22342832 PMID:11465407 RGD:2315743 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 ISO
IEP
mRNA, protein:increased expression:kidney, liver RGD PMID:12700423 PMID:19406192 RGD:2313685, RGD:2313683 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Dbh dopamine beta-hydroxylase IEP mRNA, protein:increased expression:adrenal gland (rat) RGD PMID:16396986 RGD:5130724 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248
JBrowse link
G Dcn decorin IEP RGD PMID:15713786 RGD:2311414 NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270
JBrowse link
G Defb1 defensin beta 1 IEP RGD PMID:16740310 RGD:2312491 NCBI chr16:70,298,862...70,313,604
Ensembl chr16:70,298,863...70,313,604
JBrowse link
G Dhodh dihydroorotate dehydrogenase (quinone) IEP protein:decreased activity:mammary gland (rat) RGD PMID:1476792 PMID:1723607 RGD:5132591, RGD:11040445 NCBI chr19:37,551,858...37,573,327
Ensembl chr19:37,558,177...37,591,654
JBrowse link
G Dpp4 dipeptidylpeptidase 4 ISO RGD PMID:19765579 RGD:2313699 NCBI chr 3:46,962,243...47,043,870
Ensembl chr 3:46,962,243...47,043,901
JBrowse link
G Drd1 dopamine receptor D1 treatment IEP
IDA
protein:decreased activity:striatum (rat) RGD PMID:1386820 PMID:20513244 RGD:2311600, RGD:7248621 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002
JBrowse link
G Drd2 dopamine receptor D2 IEP protein:altered activity:hypothalamus, pancreatic islet, brainstem (rat) RGD PMID:17174299 RGD:1624999 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Dusp1 dual specificity phosphatase 1 IEP mRNA, protein:decreased expression:ventricle myocardium
mRNA:increased expression:retina
RGD PMID:17647144 PMID:17063547 RGD:2298672, RGD:7771540 NCBI chr10:16,680,489...16,683,276 JBrowse link
G Ece1 endothelin converting enzyme 1 IEP mRNA:increased expression:thoracic aorta RGD PMID:23600389 RGD:7243858 NCBI chr 5:150,077,679...150,179,375
Ensembl chr 5:150,077,644...150,179,371
JBrowse link
G Edn1 endothelin 1 treatment IEP
ISO
IDA
mRNA:increased expression:heart, kidney, retina (rat)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:12458661 PMID:12967931 PMID:18516100 PMID:18351623 PMID:18351623 RGD:2313282, RGD:2312288, RGD:2312288 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Ednra endothelin receptor type A IMP RGD PMID:20690982 RGD:4892336 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049
JBrowse link
G Eef2 eukaryotic translation elongation factor 2 treatment IEP protein:decreased expression:cardiac muscle: RGD PMID:7513958 RGD:10401649 NCBI chr 7:8,533,248...8,538,518
Ensembl chr 7:8,533,116...8,559,183
JBrowse link
G Egfr epidermal growth factor receptor IDA protein:decreased tyrosine phosphorylation:cornea RGD PMID:21330660 RGD:5131482 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Eln elastin IEP mRNA:increased expression:bladder: RGD PMID:18279932 RGD:9585725 NCBI chr12:21,968,544...22,011,929
Ensembl chr12:21,968,544...22,011,928
JBrowse link
G Eno2 enolase 2 IEP protein:increased expression:brain RGD PMID:15780189 RGD:2293753 NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980
JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 IEP protein:decreased expression:retina: RGD PMID:22864860 RGD:9685437 NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827
JBrowse link
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 IEP protein,mRNA:increased expression:glial cell, retina:
protein:enzyme activity:platelet
RGD PMID:18687327 PMID:17119848 RGD:9685473, RGD:9685486 NCBI chr 1:239,425,515...239,552,323
Ensembl chr 1:239,425,430...239,552,317
JBrowse link
G Ep300 E1A binding protein p300 treatment ISO
IDA
IMP
IEP
mRNA:increased expression:retina, kidney (mouse)
mRNA:increased expression:heart (rat)
RGD PMID:18351623 PMID:22228707 PMID:18413674 PMID:18657544 RGD:2312288, RGD:7296926, RGD:2312263, RGD:2312287 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088
JBrowse link
G Epo erythropoietin IEP mRNA:increased expression:Schwann cell: RGD PMID:24673486 RGD:11041670 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946
JBrowse link
G Epor erythropoietin receptor IEP mRNA:increased expression:Schwann cell: RGD PMID:24673486 RGD:11041670 NCBI chr 8:20,489,678...20,494,257
Ensembl chr 8:20,489,678...20,494,257
JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit treatment IEP RGD PMID:22228707 RGD:7296926 NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963
JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit treatment IEP RGD PMID:22228707 RGD:7296926 NCBI chr10:2,416,259...2,448,364
Ensembl chr10:2,419,038...2,448,369
JBrowse link
G Esr1 estrogen receptor 1 IEP protein:decreased expression:penis
protein:decreased expression:vagina,nucleus
RGD PMID:15596216 PMID:16734901 RGD:2306775, RGD:2314014 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esrra estrogen related receptor, alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:23090186 NCBI chr 1:204,104,100...204,114,182
Ensembl chr 1:204,104,101...204,114,268
JBrowse link
G Ets1 ETS proto-oncogene 1, transcription factor IEP protein:increased expression:retina RGD PMID:17622743 RGD:2313849 NCBI chr 8:31,045,909...31,168,010
Ensembl chr 8:31,045,945...31,168,010
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit IEP protein:increased expression:kidney RGD PMID:23508046 RGD:9587808 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362
JBrowse link
G F11r F11 receptor IEP RGD PMID:18506084 RGD:7488940 NCBI chr13:83,873,797...83,897,388
Ensembl chr13:83,873,797...83,897,402
JBrowse link
G F2 coagulation factor II ISO protein:increased expression:kidney RGD PMID:15990447 RGD:2313862 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
JBrowse link
G F3 coagulation factor III, tissue factor ISO protein:increased activity:kidney RGD PMID:15990447 RGD:2313862 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
JBrowse link
G F7 coagulation factor VII IDA
IEP
protein:decreased activity:plasma (rat) RGD PMID:11474472 PMID:16779662 RGD:2312396, RGD:2312313 NCBI chr16:76,489,779...76,500,636
Ensembl chr16:76,489,717...76,500,610
JBrowse link
G Fabp3 fatty acid binding protein 3 IEP mRNA, protein:decreased expression:aorta RGD PMID:7744030 RGD:2307330 NCBI chr 5:142,651,962...142,658,707
Ensembl chr 5:142,651,956...142,658,718
JBrowse link
G Fabp4 fatty acid binding protein 4 IEP protein:decreased expresssion:fat cell RGD PMID:9059981 RGD:1625411 NCBI chr 2:91,580,858...91,585,578
Ensembl chr 2:91,580,885...91,585,578
JBrowse link
G Fads1 fatty acid desaturase 1 IEP RGD PMID:16099631 RGD:1625413 NCBI chr 1:206,827,724...206,842,734
Ensembl chr 1:206,827,765...206,842,734
JBrowse link
G Fas Fas cell surface death receptor onset ISO
IEP
CTD Direct Evidence: marker/mechanism
protein:increased expression:heart ventricle
CTD
RGD
PMID:16123366 PMID:20004692 PMID:19820199 RGD:2315698, RGD:2314021 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Faslg Fas ligand IEP protein:increased expression:heart ventricle RGD PMID:19820199 RGD:2314021 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fbn1 fibrillin 1 IEP protein:increased expression:renal glomerulus (rat) RGD PMID:16380460 RGD:7365080 NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889
JBrowse link
G Fcgbpl1 Fc fragment of IgG binding protein-like 1 IEP RGD PMID:20973890 RGD:5490977 NCBI chr 1:83,424,788...83,462,802
Ensembl chr 1:83,424,788...83,462,799
JBrowse link
G Fga fibrinogen alpha chain IEP protein:increased expression:plasma (rat) RGD PMID:23086277 RGD:9684989 NCBI chr 2:168,365,364...168,381,533
Ensembl chr 2:168,374,120...168,381,528
JBrowse link
G Fgf2 fibroblast growth factor 2 IEP protein:increased expression:vitreous humor RGD PMID:12663474 PMID:10792180 RGD:2315880, RGD:8655613 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
JBrowse link
G Fgf21 fibroblast growth factor 21 treatment IEP
ISO
protein:decreased expression:serum:
CTD Direct Evidence: therapeutic
CTD
RGD
PMID:23499715 PMID:23262585 PMID:25359298 PMID:23262585 RGD:10401916, RGD:10401921, RGD:10401916 NCBI chr 1:96,083,495...96,084,738
Ensembl chr 1:96,083,441...96,090,454
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 IEP
ISO
mRNA:decreased expression:heart
mRNA:decreased expression:skeletal muscle
RGD PMID:16741021 PMID:16816123 RGD:2313724, RGD:2313725 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626
JBrowse link
G Fn1 fibronectin 1 treatment IEP protein:increased expression:kidney RGD PMID:22937115 PMID:22228707 RGD:7206838, RGD:7296926 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Foxa2 forkhead box A2 IEP mRNA:increased expression:kidney cortex RGD PMID:19433262 RGD:2312358 NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326
JBrowse link
G Foxa3 forkhead box A3 IEP mRNA:increased expression:liver RGD PMID:11018767 RGD:2315085 NCBI chr 1:78,662,067...78,672,321
Ensembl chr 1:78,662,431...78,672,155
JBrowse link
G Foxo3 forkhead box O3 IEP
ISO
protein:increased phosphorylation, increased expression:glomerulus, cytoplasm:
CTD Direct Evidence: marker/mechanism
mRNA:decreased expression:liver:
CTD
RGD
PMID:23090186 PMID:23792339 PMID:17082237 PMID:12683947 PMID:17082237 RGD:10402196, RGD:10402199, RGD:10402196 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561
JBrowse link
G Foxp3 forkhead box P3 treatment IEP mRNA,protein:increased expression: peripheral blood, spleen, lymphoid node RGD PMID:18328191 PMID:32341701 RGD:38599142, RGD:38599143 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838
JBrowse link
G Fuca1 alpha-L-fucosidase 1 ISO RGD PMID:3924473 RGD:2315947 NCBI chr 5:148,152,718...148,169,972
Ensembl chr 5:148,152,700...148,169,972
JBrowse link
G Furin furin (paired basic amino acid cleaving enzyme) disease_progression IEP protein:decreased expression:kidney RGD PMID:16541018 RGD:1582625 NCBI chr 1:134,348,142...134,361,182
Ensembl chr 1:134,348,144...134,364,314
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 treatment IEP protein:increased activity:liver, kidney RGD PMID:16176150 PMID:27366200 RGD:2315960, RGD:14695533 NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase treatment IEP protein:increased expression:lens
protein:decreased expression:liver
RGD PMID:16718375 PMID:25116122 PMID:19374864 RGD:2307345, RGD:10449121, RGD:2307337 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 IEP RGD PMID:2849069 RGD:2315971 NCBI chr20:1,464,534...1,494,114
Ensembl chr20:1,464,534...1,493,994
JBrowse link
G Gal galanin and GMAP prepropeptide ISO
IEP
protein:decreased expression:pancreatic islet RGD PMID:7505518 PMID:11489087 RGD:2313742, RGD:2313740 NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959
JBrowse link
G Galp galanin-like peptide IMP
IEP
mRNA:increased expression:arcuate nucleus, pars posterior RGD PMID:16046316 PMID:15256810 RGD:2313737, RGD:2313739 NCBI chr 1:67,684,023...67,703,121
Ensembl chr 1:67,684,025...67,702,269
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase treatment IEP RGD PMID:27655796 RGD:13792671 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
JBrowse link
G Gata4 GATA binding protein 4 IEP protein:increased serine phosphorylation:heart RGD PMID:22293779 RGD:7207042 NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636
JBrowse link
G Gc GC, vitamin D binding protein IEP protein:decreased expression:serum RGD PMID:3838933 RGD:2315540 NCBI chr14:18,632,146...18,667,563
Ensembl chr14:18,632,135...18,667,567
JBrowse link
G Gcg glucagon treatment IEP RGD PMID:18996945 RGD:10402370 NCBI chr 3:47,113,914...47,122,929
Ensembl chr 3:47,113,914...47,122,929
JBrowse link
G Gck glucokinase IMP
ISO
protein:decreased activity:liver:reduced activity, energy of activation and affinity for glucose in streptozotocin diabetic rats
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:16123366 PMID:2132180 RGD:2301955 NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995
JBrowse link
G Gcnt1 glucosaminyl (N-acetyl) transferase 1 IDA mRNA:increased expression:heart RGD PMID:7560067 RGD:632804 NCBI chr 1:214,718,344...214,755,735
Ensembl chr 1:214,718,293...214,758,776
JBrowse link
G Gfpt1 glutamine fructose-6-phosphate transaminase 1 IEP protein:decreased expression:epididymal fat pad, liver, skeletal muscle RGD PMID:7589852 RGD:2313355 NCBI chr 4:119,496,691...119,546,472
Ensembl chr 4:119,496,714...119,546,471
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 IEP protein:increased activity:serum RGD PMID:18291430 RGD:2315577 NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442
JBrowse link
G Gh1 growth hormone 1 IDA
IEP
protein:decreased expression:serum, pituitary gland RGD PMID:2931155 PMID:19370419 RGD:2315682, RGD:2315655 NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078
JBrowse link
G Ghr growth hormone receptor ISO
IEP
RGD PMID:12529387 PMID:7964296 RGD:2307365, RGD:11567222 NCBI chr 2:52,541,452...52,804,960
Ensembl chr 2:52,542,594...52,804,735
JBrowse link
G Ghrh growth hormone releasing hormone treatment IDA RGD PMID:22393012 RGD:10401241 NCBI chr 3:145,992,762...146,012,528
Ensembl chr 3:145,992,763...146,011,889
JBrowse link
G Ghrhr growth hormone releasing hormone receptor IEP RGD PMID:18285528 RGD:10401258 NCBI chr 4:84,498,159...84,532,847
Ensembl chr 4:84,500,212...84,532,776
JBrowse link
G Ghrl ghrelin and obestatin prepropeptide disease_progression ISO
IEP
protein:increased expression:plasma RGD PMID:18657539 PMID:23965296 RGD:2313750, RGD:12905048 NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621
JBrowse link
G Ghsr growth hormone secretagogue receptor IEP mRNA:increased expression:Arcuate nucleus : RGD PMID:23965296 RGD:12905048 NCBI chr 2:110,268,489...110,271,865
Ensembl chr 2:110,268,489...110,271,865
JBrowse link
G Gip gastric inhibitory polypeptide IEP mRNA:increased expression:retina (rat) RGD PMID:12789546 RGD:2312548 NCBI chr10:80,968,410...80,976,506
Ensembl chr10:80,968,352...80,976,503
JBrowse link
G Gipr gastric inhibitory polypeptide receptor IEP mRNA:increased expression:retina (rat) RGD PMID:12789546 RGD:2312548 NCBI chr 1:78,804,287...78,814,462
Ensembl chr 1:78,805,593...78,814,462
JBrowse link
G Gja1 gap junction protein, alpha 1 treatment IEP
ISO
IDA
protein:increased expression:dermis
protein:decreased expression:retina, blood vessel
protein:altered expression:retina:
RGD PMID:22455314 PMID:20130277 PMID:22110070 PMID:20609064 RGD:7207269, RGD:8662383, RGD:7364887, RGD:7207415 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Gja5 gap junction protein, alpha 5 treatment IDA RGD PMID:20609064 RGD:7207415 NCBI chr 2:184,602,407...184,621,952
Ensembl chr 2:184,564,475...184,621,952
JBrowse link
G Gjb2 gap junction protein, beta 2 IEP mRNA,protein:decreased expression:retina: RGD PMID:22110070 RGD:7364887 NCBI chr15:31,260,390...31,278,222
Ensembl chr15:31,260,357...31,278,177
JBrowse link
G Gjb6 gap junction protein, beta 6 IEP RGD PMID:21567444 RGD:7364783 NCBI chr15:31,284,562...31,295,010
Ensembl chr15:31,284,419...31,294,582
JBrowse link
G Gjd3 gap junction protein, delta 3 IEP protein:decreased expression:retina: RGD PMID:23385797 RGD:7364769 NCBI chr10:83,933,694...83,935,759
Ensembl chr10:83,934,135...83,934,971
JBrowse link
G Glp1r glucagon-like peptide 1 receptor IDA RGD PMID:10580413 RGD:1624356 NCBI chr20:8,972,004...9,010,241
Ensembl chr20:8,972,004...9,010,241
JBrowse link
G Glrx glutaredoxin IEP protein:increase activity:retina: RGD PMID:17324929 RGD:9686046 NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680
JBrowse link
G Gmps guanine monophosphate synthase IEP protein:increased activity:liver (rat) RGD PMID:3043317 RGD:5135485 NCBI chr 2:148,441,369...148,491,908
Ensembl chr 2:148,435,643...148,485,875
JBrowse link
G Gnat1 G protein subunit alpha transducin 1 IEP protein:decreased expression:retina RGD PMID:15939031 RGD:1600001 NCBI chr 8:108,350,935...108,355,671
Ensembl chr 8:108,350,935...108,355,671
JBrowse link
G Gnat3 G protein subunit alpha transducin 3 IEP mRNA, protein;increased expression:taste bud RGD PMID:18824257 RGD:2302147 NCBI chr 4:17,162,500...17,212,283
Ensembl chr 4:17,162,490...17,212,283
JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial ISO CTD Direct Evidence: marker/mechanism CTD PMID:9452481 NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639
JBrowse link
G Gpd2 glycerol-3-phosphate dehydrogenase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16123366 NCBI chr 3:41,800,552...41,937,729
Ensembl chr 3:41,801,930...41,936,901
JBrowse link
G Gpx1 glutathione peroxidase 1 treatment IEP
ISO
protein:increased expression:liver
CTD Direct Evidence: marker/mechanism
protein:increased expression:glomerulus
CTD
RGD
PMID:16123366 PMID:19229592 PMID:25744399 PMID:15039483 PMID:18387670 RGD:2306606, RGD:11353782, RGD:2306161, RGD:2306607 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gpx3 glutathione peroxidase 3 IEP
IDA
ISO
protein, mRNA:decreased expression:kidney (rat)
mRNA:increased expression:heart (mouse)
RGD PMID:12753302 PMID:12753302 PMID:16651743 RGD:2312629, RGD:2312629, RGD:2312631 NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B IEP mRNA, protein:increased expression:cerebellum (rat) RGD PMID:20056114 RGD:4107025 NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279
JBrowse link
G Grk1 G protein-coupled receptor kinase 1 IEP protein:increased expression:retina RGD PMID:15939031 RGD:1600001 NCBI chr16:76,122,501...76,135,792
Ensembl chr16:76,123,842...76,135,792
JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha treatment IEP RGD PMID:8526919 RGD:10401824 NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802
JBrowse link
G Gsr glutathione-disulfide reductase treatment IEP
ISO
protein:decreased activity:plasma:
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:20620209 PMID:20187988 PMID:25050809 RGD:7257587, RGD:10401889 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gsta4 glutathione S-transferase alpha 4 IEP protein:increased expression:pancreas, kidney, liver (rat) RGD PMID:14693714 RGD:5687773 NCBI chr 8:79,066,967...79,084,193
Ensembl chr 8:79,066,934...79,084,182
JBrowse link
G Guk1 guanylate kinase 1 IEP protein:decreased expression:retina (rat) RGD PMID:17465459 RGD:5147874 NCBI chr10:43,971,514...43,988,658
Ensembl chr10:43,971,509...43,980,107
JBrowse link
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) IDA RGD PMID:20923496 RGD:6784507 NCBI chr 5:160,434,499...160,470,203
Ensembl chr 5:160,438,697...160,470,171
JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase IEP RGD PMID:7050060 RGD:2302232 NCBI chr 2:219,787,935...219,830,335
Ensembl chr 2:219,787,927...219,830,353
JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha ISO protein:decreased expression:brain RGD PMID:25260493 RGD:10047114 NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869
JBrowse link
G Hbb-bs hemoglobin, beta adult s chain IEP RGD PMID:20973890 RGD:5490977 NCBI chr 1:158,218,356...158,219,722
Ensembl chr 1:158,120,200...158,252,012
JBrowse link
G Hcn1 hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 IEP protein:increased expression:neuron: RGD PMID:19815055 RGD:9693680 NCBI chr 2:49,495,771...49,899,702
Ensembl chr 2:49,495,771...49,899,774
JBrowse link
G Hcn2 hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 IEP protein:increased expression:neuron: RGD PMID:19815055 RGD:9693680 NCBI chr 7:9,969,801...9,988,839
Ensembl chr 7:9,970,368...9,988,841
JBrowse link
G Hcn3 hyperpolarization-activated cyclic nucleotide-gated potassium channel 3 IEP protein:increased expression:neuron: RGD PMID:19815055 RGD:9693680 NCBI chr 2:174,551,866...174,567,459
Ensembl chr 2:174,551,680...174,565,966
JBrowse link
G Hdac1 histone deacetylase 1 IEP protein:increased activity:renal cortex: RGD PMID:19553350 RGD:9590229 NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111
JBrowse link
G Hdac2 histone deacetylase 2 IEP protein:increased activity:renal cortex: RGD PMID:19553350 RGD:9590229 NCBI chr20:40,548,250...40,571,609
Ensembl chr20:40,548,250...40,571,609
JBrowse link
G Hdac4 histone deacetylase 4 IEP protein:increased activity:renal cortex: RGD PMID:19553350 RGD:9590229 NCBI chr 9:92,503,467...92,750,164
Ensembl chr 9:92,507,611...92,750,164
JBrowse link
G Hgf hepatocyte growth factor IEP protein:increased expression:kidney RGD PMID:16297324 RGD:2313568 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha IEP protein:increased expression:sciatic nerve (rat) RGD PMID:15663958 RGD:8694461 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hk1 hexokinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16123366 NCBI chr20:30,230,488...30,332,161
Ensembl chr20:30,230,486...30,332,131
JBrowse link
G Hmbs hydroxymethylbilane synthase IEP protein:decreased activity:liver (rat) RGD PMID:6688350 RGD:4144808 NCBI chr 8:44,673,554...44,680,950
Ensembl chr 8:44,673,554...44,680,957
JBrowse link
G Hmgb1 high mobility group box 1 IEP associated with Endotoxemia;protein:increased expression:serum
protein:increased expression, altered localization:retina, cytoplasm
RGD PMID:19959191 PMID:23261684 RGD:2316737, RGD:10402069 NCBI chr12:5,973,062...5,978,565
Ensembl chr12:5,901,586...5,978,565
JBrowse link
G Hmgcl 3-hydroxy-3-methylglutaryl-CoA lyase IEP protein:increased activity:liver (rat) RGD PMID:5667251 RGD:2326171 NCBI chr 5:148,178,203...148,192,072
Ensembl chr 5:148,178,252...148,192,068
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase IMP RGD PMID:15111316 RGD:2313760 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 IEP protein:increased expression:pancreas RGD PMID:18452227 RGD:2302233 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 IEP protein:increased expression:liver (rat) RGD PMID:7902069 RGD:2326135 NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130
JBrowse link
G Hmox1 heme oxygenase 1 IEP
ISO
CTD Direct Evidence: marker/mechanism|therapeutic CTD
RGD
PMID:16123366 PMID:16959961 PMID:18375438 PMID:19804535 PMID:15734859 RGD:1582713 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha IEP
ISO
mRNA:decreased expression:kidney, liver
protein:increased expression:liver:
RGD PMID:18184923 PMID:19179483 RGD:2301838, RGD:12904769 NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320
JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 IEP protein:increased expression:urinary bladder (rat) RGD PMID:18337374 RGD:9685410 NCBI chr 4:80,534,659...80,545,297
Ensembl chr 4:80,534,651...80,545,249
JBrowse link
G Hnrnpk heterogeneous nuclear ribonucleoprotein K treatment IDA RGD PMID:16837467 RGD:10002795 NCBI chr17:6,262,936...6,275,001
Ensembl chr17:6,262,998...6,274,997
JBrowse link
G Hp haptoglobin IEP protein:increased expression:serum RGD PMID:11072799 RGD:1626381 NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 IEP protein:decreased activity:liver (rat) RGD PMID:3043317 RGD:5135485 NCBI chr  X:132,736,175...132,768,149
Ensembl chr  X:132,736,096...132,768,154
JBrowse link
G Hras HRas proto-oncogene, GTPase IEP mRNA, protein:increased expression:retina blood vessel RGD PMID:18514235 RGD:2314841 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14697232 NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 IEP mRNA:decreased expression:brain (rat) RGD PMID:21104931 RGD:5686396 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 IEP RGD PMID:17280490 RGD:1624229 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Hspg2 heparan sulfate proteoglycan 2 IEP mRNA:decreased expression:retina RGD PMID:9068943 RGD:1624265 NCBI chr 5:149,677,437...149,778,594
Ensembl chr 5:149,677,476...149,778,594
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A IEP protein:increased expression:lung RGD PMID:21521772 RGD:5135278 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928
JBrowse link
G Iapp islet amyloid polypeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:16123366 NCBI chr 4:175,237,013...175,244,373
Ensembl chr 4:175,237,115...175,242,920
JBrowse link
G Icam1 intercellular adhesion molecule 1 treatment ISO
IEP
mRNA:increased expression:aorta
CTD Direct Evidence: marker/mechanism
protein:increased expression:serum
CTD
RGD
PMID:14871415 PMID:20388520 PMID:24513509 PMID:18093596 PMID:20136425 More... RGD:2306988, RGD:8547703, RGD:2306987 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:16123366 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
JBrowse link
G Ide insulin degrading enzyme IEP protein:decreased expression:cerebral cortex RGD PMID:29940507 RGD:13792791 NCBI chr 1:235,002,984...235,102,448
Ensembl chr 1:234,995,351...235,102,440
JBrowse link
G Ifnar1 interferon alpha and beta receptor subunit 1 IMP RGD PMID:27999109 RGD:12910492 NCBI chr11:30,725,774...30,752,227
Ensembl chr11:30,725,790...30,749,979
JBrowse link
G Ifnar1em1 interferon alpha and beta receptor subunit 1; CRISPR/Cas9 induced mutant 1 IMP RGD PMID:27999109 RGD:12910492
G Ifnar1em2 interferon alpha and beta receptor subunit 1; CRISPR/Cas9 induced mutant 2 IMP RGD PMID:27999109 RGD:12910492
G Ifng interferon gamma ISO
IEP
mRNA:increased expression:pancreas
CTD Direct Evidence: marker/mechanism
protein:increased expression:retina
CTD
RGD
PMID:21340626 PMID:18789669 PMID:20213480 RGD:2311492, RGD:5147915 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Igf1 insulin-like growth factor 1 IEP
ISO
protein:decreased expression:cerebellum, serum
CTD Direct Evidence: therapeutic
mRNA,protein:decreased expression:corpus cavernosum:
protein:decreased expression:oviduct
protein:decreased expression:heart
CTD
RGD
PMID:24632065 PMID:19382144 PMID:22133301 PMID:18676006 PMID:20555424 RGD:2306671, RGD:10046054, RGD:2311502, RGD:4142788 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Igf1r insulin-like growth factor 1 receptor IEP
ISO
protein:decreased phosphorylation:heart
protein:decreased expression:oviduct
RGD PMID:20555424 PMID:18676006 RGD:4142788, RGD:2311502 NCBI chr 1:121,549,839...121,838,545
Ensembl chr 1:121,550,743...121,831,777
JBrowse link
G Igf2 insulin-like growth factor 2 treatment ISO
IEP
DNA, mRNA:hypermethylation, decreased expression
mRNA:decreased expression:brain
protein:increased expression:oviduct
protein:increased expression:multiple
RGD PMID:18724775 PMID:23364485 PMID:10686593 PMID:18676006 PMID:17184497 RGD:2311511, RGD:10402565, RGD:5509973, RGD:2311502, RGD:2311513 NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018
JBrowse link
G Igf2r insulin-like growth factor 2 receptor ISO protein:increased expression:oviduct RGD PMID:18676006 RGD:2311502 NCBI chr 1:47,979,109...48,067,501
Ensembl chr 1:47,979,109...48,067,501
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 treatment ISO
IMP
IEP
protein:increased expression:skeletal muscle
mRNA, protein:increased expression:penis
RGD PMID:16180585 PMID:25582342 PMID:18068478 RGD:2313766, RGD:12743617, RGD:2289159 NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta IDA protein:increased phosphorylation:liver RGD PMID:20362663 RGD:7495777 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
JBrowse link
G Il10 interleukin 10 IEP
ISO
protein:increase expression:serum RGD PMID:18787467 PMID:18779928 RGD:2308945, RGD:2308946 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il17a interleukin 17A IEP protein:increased expression:gingiva (rat) RGD PMID:21826658 RGD:9068940 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
JBrowse link
G Il1a interleukin 1 alpha IEP protein:increased expression:heart RGD PMID:20555424 RGD:4142788 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta IEP
ISO
IDA
mRNA:increased expression:skeletal muscle
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:12123627 PMID:17669395 PMID:23197974 RGD:1626620, RGD:7175529 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO human gene in a rat model RGD PMID:19545727 PMID:17221214 PMID:8037760 RGD:6907397, RGD:8551855, RGD:6907425 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
JBrowse link
G Il2 interleukin 2 IEP protein:increased expression:retina RGD PMID:20213480 RGD:5147915 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il2ra interleukin 2 receptor subunit alpha IDA RGD PMID:18503494 RGD:2311530 NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697
JBrowse link
G Il4 interleukin 4 treatment IEP RGD PMID:25191525 RGD:10402795 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il4r interleukin 4 receptor ISO RGD PMID:12165974 RGD:4889983 NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980
JBrowse link
G Il6 interleukin 6 IEP
ISO
IDA
protein:increased expression:heart
CTD Direct Evidence: marker/mechanism
protein:increased expression:extracellular space (rat)
protein:increased expression:blood
CTD
RGD
PMID:22138235 PMID:20555424 PMID:24582317 PMID:19328014 PMID:18976114 RGD:4142788, RGD:11049554, RGD:2307252, RGD:2306984 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Insig1 insulin induced gene 1 ISO RGD PMID:16327801 RGD:2308858 NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
JBrowse link
G Insr insulin receptor disease_progression
treatment
IDA
IEP
ISO
protein:decreased expression:erythrocyte (rat)
mRNA:increased expression:liver nuclei, liver cell membrane (rat)
associated with streptozocin;protein:altered activity:liver plasma membrane (rat)
CTD Direct Evidence: marker/mechanism
mRNA, protein:increased expression:liver, adipose tissue (rat)
protein:decreased expression:kidney
CTD
RGD
PMID:9243097 PMID:22138235 PMID:18376071 PMID:1280238 PMID:2180315 More... RGD:2307339, RGD:15036814, RGD:14981592, RGD:10403045, RGD:2307025, RGD:2290475 NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883
JBrowse link
G Irs1 insulin receptor substrate 1 treatment IDA
ISO
IEP
CTD Direct Evidence: marker/mechanism
mRNA, protein:decreased expression:multiple
CTD
RGD
PMID:22138235 PMID:22983684 PMID:22820932 RGD:7207061, RGD:7207063 NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122
JBrowse link
G Irs2 insulin receptor substrate 2 IEP
ISO
protein:decreased phosphorylation:heart
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:25808216 PMID:20555424 RGD:4142788 NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482
JBrowse link
G Isg15 ISG15 ubiquitin-like modifier IEP RGD PMID:20973890 RGD:5490977 NCBI chr 5:166,784,148...166,785,435
Ensembl chr 5:166,784,148...166,785,435
JBrowse link
G Itga3 integrin subunit alpha 3 IEP protein:decreased expression:renal cortex (rat) RGD PMID:20525748 RGD:2325818 NCBI chr10:79,990,160...80,022,206
Ensembl chr10:79,990,161...80,022,118
JBrowse link
G Itgb1 integrin subunit beta 1 IEP protein:decreased expression:epidermal stem cell (rat) RGD PMID:20187441 RGD:2325322 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
JBrowse link
G Itgb3 integrin subunit beta 3 IEP protein:increased expression:aorta: RGD PMID:12606526 RGD:8693385 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
JBrowse link
G Jak3 Janus kinase 3 IEP protein:increased expression:retina RGD PMID:21575160 RGD:11533943 NCBI chr16:18,386,330...18,398,542
Ensembl chr16:18,386,405...18,398,536
JBrowse link
G Kcna2 potassium voltage-gated channel subfamily A member 2 IEP RGD PMID:17982915 RGD:7242761 NCBI chr 2:194,704,555...194,718,387
Ensembl chr 2:194,704,639...194,718,400
JBrowse link
G Kcna5 potassium voltage-gated channel subfamily A member 5 IEP RGD PMID:17982915 RGD:7242761 NCBI chr 4:159,354,689...159,358,173
Ensembl chr 4:159,350,097...159,357,697
JBrowse link
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 IEP mRNA:decreased expression:left heart ventricle RGD PMID:19267230 RGD:7243942 NCBI chr11:31,517,176...31,530,026
Ensembl chr11:31,295,614...31,530,043
JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 IEP
ISO
protein:decreased expression:brain
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:16123366 PMID:23785408 RGD:7296920 NCBI chr 1:96,591,048...96,594,574
Ensembl chr 1:96,591,049...96,594,082
JBrowse link
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 IEP mRNA, protein:decreased expression:aorta, smooth muscle RGD PMID:24589593 RGD:10412030 NCBI chr15:302,078...1,001,198
Ensembl chr15:302,214...1,001,198
JBrowse link
G Kcnmb1 potassium calcium-activated channel subfamily M regulatory beta subunit 1 IEP protein:decreased expression:aorta, smooth muscle RGD PMID:24589593 RGD:10412030 NCBI chr10:18,557,510...18,614,824
Ensembl chr10:18,557,904...18,565,798
JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 IEP mRNA, protein:increased expression:aorta, smooth muscle RGD PMID:24589593 RGD:10412030 NCBI chr 1:79,956,380...79,974,354
Ensembl chr 1:79,959,322...79,974,340
JBrowse link
G Kdr kinase insert domain receptor ISO
IEP
mRNA:decreased expression:skeletal muscle
mRNA:increased expression:retina
mRNA:decreased expression:heart
RGD PMID:16816123 PMID:22121831 PMID:16741021 RGD:2313725, RGD:5684538, RGD:2313724 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
JBrowse link
G Khk ketohexokinase IEP RGD PMID:6088170 RGD:2302253 NCBI chr 6:25,445,298...25,455,834
Ensembl chr 6:25,445,300...25,455,717
JBrowse link
G Kif1a kinesin family member 1A IEP mRNA:increased expression:hippocampus RGD PMID:23776493 RGD:11059542 NCBI chr 9:93,563,033...93,647,412
Ensembl chr 9:93,563,045...93,647,480
JBrowse link
G Kif5b kinesin family member 5B IEP mRNA:increased expression:hippocampus RGD PMID:23776493 RGD:11059542 NCBI chr17:51,489,873...51,527,508
Ensembl chr17:51,489,944...51,527,508
JBrowse link
G Klk1 kallikrein 1 IEP mRNA:decreased expression:myocardium RGD PMID:10604522 RGD:1641812 NCBI chr 1:94,642,722...94,646,714
Ensembl chr 1:94,642,687...94,646,754
JBrowse link
G Kmt5c lysine methyltransferase 5C IEP mRNA:increased expression:retina RGD PMID:21357467 RGD:9586742 NCBI chr 1:69,099,531...69,107,145
Ensembl chr 1:69,099,539...69,107,145
JBrowse link
G Lcn2 lipocalin 2 IEP mRNA:increased expression:retina (rat)
protein:increased expression:urine
RGD PMID:15623795 PMID:23085980 RGD:2316515, RGD:7245484 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
JBrowse link
G Lct lactase IDA RGD PMID:16021836 RGD:1600251 NCBI chr13:39,781,929...39,824,456
Ensembl chr13:39,781,929...39,824,456
JBrowse link
G Ldlr low density lipoprotein receptor IEP mRNA:decreased expression:liver RGD PMID:18054320 RGD:2324626 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Lep leptin onset IMP
ISO
IDA
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:28242381 PMID:31313498 PMID:31483951 PMID:19491210 PMID:19428774 More... RGD:2311124, RGD:2311126, RGD:5128579 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lepr leptin receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:15093691 PMID:16427799 PMID:17065336 PMID:19452630 PMID:19478208 More... NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
G Lgals3 galectin 3 treatment IEP RGD PMID:21249158 RGD:9685210 NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025
JBrowse link
G Lipc lipase C, hepatic type IDA
IEP
protein:decreased activity:liver (rat) RGD PMID:18758746 PMID:1868959 RGD:2307432, RGD:2308849 NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
JBrowse link
G Litaf lipopolysaccharide-induced TNF factor IEP protein:increased expression:retina RGD PMID:21575160 RGD:11533943 NCBI chr10:4,656,308...4,692,981
Ensembl chr10:4,625,552...4,692,763
JBrowse link
G Lpin1 lipin 1 IEP mRNA:increased expression:skeletal muscle RGD PMID:14718385 RGD:1641826 NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097
JBrowse link
G Lpl lipoprotein lipase treatment IEP
IDA
RGD PMID:18780778 PMID:27158912 RGD:2313303, RGD:13794379 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
JBrowse link
G Lrp2 LDL receptor related protein 2 IEP protein:decreased expression:kidney, proximal convoluted tubule, apical plasma membrane RGD PMID:11685557 RGD:1641843 NCBI chr 3:54,189,305...54,346,769
Ensembl chr 3:54,189,308...54,346,708
JBrowse link
G Ltbp1 latent transforming growth factor beta binding protein 1 IEP RGD PMID:17574405 RGD:2302087 NCBI chr 6:20,029,629...20,425,339
Ensembl chr 6:20,029,629...20,425,349
JBrowse link
G Mafa MAF bZIP transcription factor A treatment ISO RGD PMID:28487936 RGD:13506743 NCBI chr 7:107,432,292...107,435,061
Ensembl chr 7:107,433,605...107,434,690
JBrowse link
G Map2k3 mitogen activated protein kinase kinase 3 IEP mRNA:increased expression:kidney, glomerulus RGD PMID:11473637 RGD:7495813 NCBI chr10:45,608,145...45,629,492
Ensembl chr10:45,607,163...45,629,492
JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 IEP mRNA:increased expression:kidney, glomerulus RGD PMID:11473637 RGD:7495813 NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18342293 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800
JBrowse link
G Mapk1 mitogen activated protein kinase 1 IEP
IDA
protein:decreased phosphorylation:cornea RGD PMID:22045654 PMID:21330660 RGD:7243969, RGD:5131482 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 IDA protein:decreased phosphorylation:cornea RGD PMID:21330660 RGD:5131482 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapt microtubule-associated protein tau treatment IDA RGD PMID:28400135 RGD:13800903 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
JBrowse link
G Mas1 MAS1 proto-oncogene, G protein-coupled receptor IEP mRNA:increased expression:renal cortex (rat) RGD PMID:18679036 RGD:2313799 NCBI chr 1:47,879,956...47,911,500
Ensembl chr 1:47,880,309...47,911,709
JBrowse link
G Mbp myelin basic protein IDA RGD PMID:23667870 RGD:7327197 NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404
JBrowse link
G Mdm2 MDM2 proto-oncogene IEP protein:increased degradation:myocardium RGD PMID:23530877 RGD:10412313 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Mef2a myocyte enhancer factor 2a IEP mRNA:increased expression:heart RGD PMID:18413674 RGD:2312263 NCBI chr 1:120,847,874...120,982,488
Ensembl chr 1:120,850,080...120,981,948
JBrowse link
G Mef2c myocyte enhancer factor 2C IEP mRNA:increased expression:heart RGD PMID:18413674 RGD:2312263 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase IEP mRNA, protein:increased expression:kidney, tubule, epithelium (rat) RGD PMID:8997394 RGD:2317555 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876
JBrowse link
G Mfge8 milk fat globule EGF and factor V/VIII domain containing ISO CTD Direct Evidence: marker/mechanism CTD PMID:21505870 NCBI chr 1:133,064,665...133,080,069
Ensembl chr 1:133,064,665...133,080,073
JBrowse link
G Mfn2 mitofusin 2 treatment IEP protein:increased expression:heart, mitochondrion (rat) RGD PMID:28483572 PMID:27998959 RGD:12910731, RGD:12910739 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
JBrowse link
G Mif macrophage migration inhibitory factor ISO protein:increased expression:pancreatic islet RGD PMID:15790730 RGD:1641951 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504
JBrowse link
G Mmp1 matrix metallopeptidase 1 IEP protein:increased expression:periodontal ligament, alveolar bone of mandible (rat) RGD PMID:20082587 RGD:7207377 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
JBrowse link
G Mmp2 matrix metallopeptidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21963884 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp9 matrix metallopeptidase 9 treatment IEP
ISO
protein:increased expression:kidney
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:retina
CTD
RGD
PMID:21963884 PMID:22191573 PMID:17569353 PMID:23089644 PMID:23423566 RGD:2290354, RGD:8547974, RGD:8547881 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mpo myeloperoxidase IEP
ISO
protein:increased activity:liver:
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:20388520 PMID:18436980 RGD:2317971 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II ISO CTD Direct Evidence: marker/mechanism CTD PMID:14563825 NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689
JBrowse link
G Mt-cyb mitochondrially encoded cytochrome b IEP mRNA:decreased expression:heart RGD PMID:15126286 RGD:1578536 NCBI chr MT:14,136...15,278
Ensembl chr MT:14,136...15,278
JBrowse link
G Mt-nd1 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14563825 NCBI chr MT:2,740...3,694
Ensembl chr MT:2,740...3,694
JBrowse link
G Mthfr methylenetetrahydrofolate reductase IEP protein:decreased activity:kidney (rat) RGD PMID:9836532 RGD:6893689 NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797
JBrowse link
G Mtor mechanistic target of rapamycin kinase IDA protein:hyperphosphorylation:muscle RGD PMID:28536139 RGD:13506787 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase IEP protein:decreased activity:liver RGD PMID:18936199 RGD:7207081 NCBI chr17:58,219,998...58,308,560
Ensembl chr17:58,220,071...58,304,822
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor IEP mRNA:increased expression:renal cortex (rat) RGD PMID:18030501 RGD:7207459 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase IEP protein:decreased expression:fat cell RGD PMID:18410550 RGD:2311099 NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14871415 PMID:16380483 NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646
JBrowse link
G Ncf2 neutrophil cytosolic factor 2 IDA
IEP
protein:altered localization:glomerulus
protein:increased expression:heart, membrane fraction
RGD PMID:14514646 PMID:18061195 RGD:2314451, RGD:2314434 NCBI chr13:64,955,502...64,986,289
Ensembl chr13:64,955,503...64,986,277
JBrowse link
G Ndufs2 NADH:ubiquinone oxidoreductase core subunit S2 IEP protein:decreased expression:dorsal root ganglia (rat) RGD PMID:20876714 RGD:6484699 NCBI chr13:83,654,402...83,671,474
Ensembl chr13:83,654,406...83,671,420
JBrowse link
G Ndufs3 NADH:ubiquinone oxidoreductase core subunit S3 IEP protein:decreased expression:dorsal root ganglia (rat)
mRNA, protein:decreased expression:brain
RGD PMID:20876714 PMID:22387129 RGD:6484699, RGD:13824971 NCBI chr 3:76,876,646...76,883,824
Ensembl chr 3:76,876,646...76,883,824
JBrowse link
G Nefh neurofilament heavy chain treatment IEP RGD PMID:12941778 RGD:9698428 NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351
JBrowse link
G Nefm neurofilament medium chain treatment IEP RGD PMID:12941778 RGD:9698428 NCBI chr15:42,360,449...42,365,753
Ensembl chr15:42,360,454...42,365,755
JBrowse link
G Neurod1 neuronal differentiation 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16123366 NCBI chr 3:64,360,222...64,363,526
Ensembl chr 3:64,359,395...64,363,649
JBrowse link
G Neurog3 neurogenin 3 ISO RGD PMID:19819964 RGD:2313774 NCBI chr20:30,079,780...30,081,262
Ensembl chr20:30,079,780...30,081,262
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 treatment ISO
IEP
protein:increased localization:blood, mononuclear cell, nucleus RGD PMID:22869588 PMID:23331247 PMID:24740568 RGD:10412694, RGD:7244270, RGD:10412720 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkb2 nuclear factor kappa B subunit 2 IEP RGD PMID:18633731 RGD:2298775 NCBI chr 1:245,164,586...245,173,225
Ensembl chr 1:245,165,950...245,173,213
JBrowse link
G Nfkbia NFKB inhibitor alpha treatment IEP
IDA
protein:decreased expression:kidney RGD PMID:22483164 PMID:20188823 RGD:10413864, RGD:10413873 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Ngf nerve growth factor IEP mRNA, protein:decreased expression:sciatic nerve
protein:increased expression:retina
RGD PMID:19149268 PMID:21136036 RGD:2303795, RGD:5144144 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
JBrowse link
G Ngfr nerve growth factor receptor IEP protein:increased expression:retina RGD PMID:21136036 RGD:5144144 NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518
JBrowse link
G Nkx6-1 NK6 homeobox 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16123366 NCBI chr14:7,969,756...7,976,689
Ensembl chr14:7,969,756...7,976,681
JBrowse link
G Nos1 nitric oxide synthase 1 IDA protein:decreased dimerization:stomach RGD PMID:17347455 RGD:1642144 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
JBrowse link
G Nos2 nitric oxide synthase 2 no_association IEP
ISO
associated with Infarction, Middle Cerebral Artery; protein:increased expression:brain (rat)
CTD Direct Evidence: marker/mechanism
protein:increased expression:renal glomerulus (rat)
CTD
RGD
PMID:16380483 PMID:16959961 PMID:21993016 PMID:9349594 RGD:5509105, RGD:5509107 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nos3 nitric oxide synthase 3 treatment IDA
IEP
ISO
CTD Direct Evidence: marker/mechanism
protein:decreased expression:thoracic aorta (mouse)
protein:increased expression:heart
CTD
RGD
PMID:11696579 PMID:14871415 PMID:15490108 PMID:16959961 PMID:18266981 More... RGD:4892007, RGD:13450939, RGD:7777108, RGD:7777108, RGD:2292100 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Nox4 NADPH oxidase 4 IEP protein:increased expression:aorta RGD PMID:19686728 RGD:2324658 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406
JBrowse link
G Npc1l1 NPC1 like intracellular cholesterol transporter 1 IEP mRNA:increased expression:intestine, liver RGD PMID:17292734 RGD:1642185 NCBI chr14:81,071,448...81,091,113
Ensembl chr14:81,071,451...81,091,113
JBrowse link
G Nppa natriuretic peptide A IEP protein:decreased expression:retina
protein:increased expression:plasma, kidney, heart;
RGD PMID:15789000 PMID:17151304 RGD:1580773, RGD:7248602 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
JBrowse link
G Nppb natriuretic peptide B IEP protein:increased expression:atrium myocardium, plasma RGD PMID:17151299 RGD:1642199 NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168
JBrowse link
G Npy neuropeptide Y IEP protein:increased expression:paraventricular nucleus of hypothalamus RGD PMID:21042571 RGD:10448960 NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495
JBrowse link
G Npy1r neuropeptide Y receptor Y1 IEP RGD PMID:18201831 RGD:10448967 NCBI chr16:23,037,788...23,047,330
Ensembl chr16:23,037,789...23,046,759
JBrowse link
G Npy2r neuropeptide Y receptor Y2 IEP RGD PMID:18201831 RGD:10448967 NCBI chr 2:167,901,999...167,912,165
Ensembl chr 2:167,903,879...167,905,024
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 ISO CTD Direct Evidence: therapeutic CTD PMID:23458895 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 IEP mRNA:decreased expression:liver RGD PMID:15047603 RGD:1625080 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 treatment IEP RGD PMID:20636876 RGD:9835393 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 IEP protein:increased expression:placenta RGD PMID:21744335 RGD:12879479 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Nrp1 neuropilin 1 ISO mRNA:decreased expression:skeletal muscle RGD PMID:16816123 RGD:2313725 NCBI chr19:56,359,455...56,514,628
Ensembl chr19:56,359,455...56,513,633
JBrowse link
G Nt5e 5' nucleotidase, ecto IEP protein:increased expression:cerebral cortex, synaptosome (rat) RGD PMID:19723569 RGD:5134343 NCBI chr 8:89,271,046...89,314,918
Ensembl chr 8:89,270,696...89,314,881
JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 IEP protein:increased tyrosine nitration, decreased tyrosine phosphorylation:retina RGD PMID:21136036 PMID:22044876 RGD:5144144, RGD:5684337 NCBI chr 2:173,236,961...173,253,806
Ensembl chr 2:173,236,963...173,253,770
JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 IEP mRNA:decreased expression:dorsal root ganglion RGD PMID:9541170 RGD:2325654 NCBI chr 1:132,116,472...132,503,849
Ensembl chr 1:132,132,849...132,503,286
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase IEP
ISO
protein:altered localization:pancreatic islet RGD PMID:18676009 PMID:18599524 PMID:15677345 RGD:2317137, RGD:8657153, RGD:8657146 NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766
JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase treatment IDA RGD PMID:15561949 RGD:9590198 NCBI chr  X:66,771,278...66,816,148
Ensembl chr  X:66,771,349...66,816,146
JBrowse link
G Oprk1 opioid receptor, kappa 1 IEP protein:increased expression:sciatic nerve, peroneal nerve: RGD PMID:16924480 RGD:9834947 NCBI chr 5:13,860,016...13,877,823
Ensembl chr 5:13,860,021...13,877,823
JBrowse link
G Oprm1 opioid receptor, mu 1 IDA RGD PMID:16901587 RGD:2316626 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409
JBrowse link
G Osbp oxysterol binding protein IDA protein:increased tyrosine phosphorylation:aorta RGD PMID:18230613 RGD:2291921 NCBI chr 1:208,888,697...208,918,511
Ensembl chr 1:208,887,895...208,918,506
JBrowse link
G Otc ornithine transcarbamylase IEP protein:decreased activity:small intestine (rat) RGD PMID:9628242 RGD:4144123 NCBI chr  X:12,453,834...12,529,954
Ensembl chr  X:12,453,834...12,566,918
JBrowse link
G Oxct1 3-oxoacid CoA transferase 1 IEP protein:decreased activity:heart, mitochondrion (rat) RGD PMID:3548709 RGD:2326100 NCBI chr 2:53,236,370...53,384,715
Ensembl chr 2:53,236,368...53,384,714
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 ISO RGD PMID:18657544 RGD:2312287 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pax6 paired box 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16123366 NCBI chr 3:92,128,772...92,157,022
Ensembl chr 3:92,135,637...92,157,014
JBrowse link
G Pc pyruvate carboxylase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16123366 NCBI chr 1:201,799,374...201,898,412
Ensembl chr 1:201,804,267...201,898,380
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 IDA
ISO
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:20363216 PMID:17651728 RGD:2311641 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
JBrowse link
G Pcsk1 proprotein convertase subtilisin/kexin type 1 IEP
ISO
mRNA, protein:increased expression:spleen, spleen white pulp (rat)
protein:increased expression:pancreatic alpha cell (mouse)
mRNA, protein:increased expression:spleen (mouse)
RGD PMID:11730986 PMID:17698597 PMID:11730986 RGD:2308905, RGD:2308931, RGD:2308905 NCBI chr 2:4,395,543...4,442,434
Ensembl chr 2:4,395,543...4,442,434
JBrowse link
G Pcsk2 proprotein convertase subtilisin/kexin type 2 IEP
ISO
mRNA:increased expression:spleen
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:16123366 PMID:11730986 RGD:2308905 NCBI chr 3:130,880,422...131,183,127
Ensembl chr 3:130,880,422...131,183,127
JBrowse link
G Pde3a phosphodiesterase 3A IEP mRNA, protein:increased expression:mesenteric artery RGD PMID:12793980 RGD:2300416 NCBI chr 4:174,172,804...174,443,944
Ensembl chr 4:174,172,868...174,438,274
JBrowse link
G Pde5a phosphodiesterase 5A IMP RGD PMID:19542492 RGD:2314461 NCBI chr 2:210,858,515...211,003,480
Ensembl chr 2:210,858,063...210,999,701
JBrowse link
G Pdgfb platelet derived growth factor subunit B IEP
IDA
ISO
mRNA:increased expression:glomerulus
mRNA: increased expression: mesenteric artery
mRNA:increased expression:retina
mRNA:decreased expression:retina
RGD PMID:8094359 PMID:9763208 PMID:21367419 PMID:12606528 PMID:14685146 RGD:2311650, RGD:10449499, RGD:6483042, RGD:1581759, RGD:2311648 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta IEP protein:increased expression:glomerulus RGD PMID:10802145 RGD:2311654 NCBI chr18:54,500,002...54,538,843
Ensembl chr18:54,499,964...54,538,843
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14563825 NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850
JBrowse link
G Pdp2 pyruvate dehydrogenase phosphatase catalytic subunit 2 IEP RGD PMID:12765946 RGD:1582364 NCBI chr19:386,408...394,068
Ensembl chr19:386,406...394,074
JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 IMP
ISO
IEP
IDA
CTD Direct Evidence: marker/mechanism
protein:increased expression:pancreatic delta cell (rat)
protein:increased expression:pancreas (rat)
CTD
RGD
PMID:16123366 PMID:17460716 PMID:15561947 PMID:14988244 PMID:17235568 More... RGD:2311224, RGD:2311226, RGD:1357906, RGD:2311225, RGD:2311311 NCBI chr12:7,757,865...7,763,064
Ensembl chr12:7,757,865...7,763,064
JBrowse link
G Pdyn prodynorphin IEP protein:increased expression:sciatic nerve, peroneal nerve, tibial nerve, footpad skin: RGD PMID:16924480 RGD:9834947 NCBI chr 3:116,900,990...116,913,334
Ensembl chr 3:116,900,992...116,913,334
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 IEP protein:decreased expression:corpus callosum, endothelium (rat) RGD PMID:21967314 RGD:6771179 NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116
JBrowse link
G Pemt phosphatidylethanolamine N-methyltransferase IEP protein:increased expression:liver RGD PMID:17116711 RGD:1642370 NCBI chr10:44,775,910...44,849,990
Ensembl chr10:44,775,911...44,850,013
JBrowse link
G Pfas phosphoribosylformylglycinamidine synthase IEP protein:increased activity:liver (rat) RGD PMID:3043317 RGD:5135485 NCBI chr10:53,690,301...53,711,811
Ensembl chr10:53,691,626...53,708,420
JBrowse link
G Pfkm phosphofructokinase, muscle ISO CTD Direct Evidence: marker/mechanism CTD PMID:14563825 NCBI chr 7:129,221,679...129,259,192
Ensembl chr 7:129,221,653...129,259,192
JBrowse link
G Pgf placental growth factor IEP mRNA, protein:decreased expression:placenta, trophoblast cell RGD PMID:17917370 RGD:6483782 NCBI chr 6:104,816,102...104,826,685
Ensembl chr 6:104,816,104...104,826,685
JBrowse link
G Phka1 phosphorylase kinase regulatory subunit alpha 1 IDA RGD PMID:11692172 RGD:1599897 NCBI chr  X:67,601,302...67,738,504
Ensembl chr  X:67,601,302...67,738,455
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 IEP protein:increased expression:gastrocnemius (rat) RGD PMID:18430054 RGD:2307338 NCBI chr 2:32,878,942...32,963,611
Ensembl chr 2:32,882,032...32,963,631
JBrowse link
G Pklr pyruvate kinase L/R IEP
ISO
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:20363216 PMID:16900249 RGD:1625589 NCBI chr 2:174,543,008...174,551,863
Ensembl chr 2:174,543,039...174,551,870
JBrowse link
G Plcb3 phospholipase C beta 3 IEP protein:decreased expression:heart left ventricle RGD PMID:15362504 RGD:2314509 NCBI chr 1:204,143,257...204,160,384
Ensembl chr 1:204,144,956...204,160,228
JBrowse link
G Plcg1 phospholipase C, gamma 1 IEP protein:increased tyrosine phosphorylation:lens RGD PMID:17612968 RGD:2299877 NCBI chr 3:149,385,587...149,416,330
Ensembl chr 3:149,385,587...149,416,330
JBrowse link
G Pnmt phenylethanolamine-N-methyltransferase IEP protein:increased expression:adrenal gland (rat) RGD PMID:16396986 RGD:5130724 NCBI chr10:83,383,019...83,386,557
Ensembl chr10:83,384,923...83,386,556
JBrowse link
G Polg DNA polymerase gamma, catalytic subunit IEP
ISO
IDA
mRNA,protein:decreased expression:retina,mitochondrion:
DNA:hypermethylation:promoter:
RGD PMID:22743328 PMID:22229649 PMID:22743328 RGD:8694093, RGD:8694187, RGD:8694093 NCBI chr 1:133,382,764...133,399,578
Ensembl chr 1:133,382,766...133,398,567
JBrowse link
G Polg2 DNA polymerase gamma 2, accessory subunit ISO mRNA,protein:decreased expression:retina,mitochondrion: RGD PMID:22229649 RGD:8694187 NCBI chr10:91,712,586...91,723,008
Ensembl chr10:91,712,586...91,723,008
JBrowse link
G Pon1 paraoxonase 1 ISO RGD PMID:18358245 PMID:18358245 RGD:2313268, RGD:2313268 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:12967931 PMID:14563825 PMID:23090186 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta IEP mRNA, protein:decreased expression:heart RGD PMID:18573863 RGD:2313781 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma IEP
ISO
mRNA:altered expression:aorta, kidney cortex, retina
CTD Direct Evidence: marker/mechanism
protein:decreased expression:retina
CTD
RGD
PMID:12967931 PMID:16123366 PMID:21757225 PMID:18641696 PMID:18806296 RGD:2301849, RGD:2301844 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha treatment IEP
ISO
IMP
IDA
mRNA:decreased expression:pancreatic islet
CTD Direct Evidence: marker/mechanism
protein:decreased expression:dorsal root ganglia (mouse)
CTD
RGD
PMID:14563825 PMID:18270681 PMID:19520786 PMID:22561641 PMID:23272147 RGD:2311391, RGD:2311445, RGD:7242175, RGD:7241845 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Ppat phosphoribosyl pyrophosphate amidotransferase IEP protein:increased activity:kidney (rat) RGD PMID:2451505 RGD:5135016 NCBI chr14:31,215,741...31,250,144
Ensembl chr14:31,216,165...31,250,144
JBrowse link
G Prkca protein kinase C, alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:12198386 NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012
JBrowse link
G Prkcb protein kinase C, beta IEP protein:increased expression:myocardium RGD PMID:17250813 RGD:1625511 NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536
JBrowse link
G Prkcd protein kinase C, delta IEP
ISO
protein:increased expression:kidney
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:12198386 PMID:11576956 RGD:1642532 NCBI chr16:5,769,226...5,807,214
Ensembl chr16:5,769,215...5,799,352
JBrowse link
G Prkce protein kinase C, epsilon ISO CTD Direct Evidence: marker/mechanism CTD PMID:12198386 NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719
JBrowse link
G Prkci protein kinase C, iota IEP protein:increased expression:ventricle myocardium, membrane fraction RGD PMID:14691046 RGD:2314944 NCBI chr 2:112,321,919...112,382,305
Ensembl chr 2:112,321,929...112,382,352
JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 treatment IEP protein:decreased expression:aorta RGD PMID:20186099 PMID:15939056 RGD:7775064, RGD:7777110 NCBI chr 1:228,409,883...229,638,794
Ensembl chr 1:228,408,947...229,639,080
JBrowse link
G Prkra protein activator of interferon induced protein kinase EIF2AK2 IEP RGD PMID:21897745 RGD:7777145 NCBI chr 3:61,575,447...61,594,393
Ensembl chr 3:61,575,447...61,594,347
JBrowse link
G Psmb9 proteasome 20S subunit beta 9 IEP mRNA:increased expression:hippocampus (rat) RGD PMID:20968039 RGD:9850284 NCBI chr20:4,667,044...4,672,512
Ensembl chr20:4,666,046...4,672,512
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 IEP protein:decreased expression:spinal cord RGD PMID:12086957 RGD:727386 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IEP
ISO
CTD Direct Evidence: marker/mechanism
protein:increased expression:lung
protein:increased expression:sciatic nerve
CTD
RGD
PMID:14514642 PMID:21414306 PMID:18706904 PMID:21521772 PMID:17720896 RGD:2300222, RGD:5135278, RGD:1642588 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Ptprn protein tyrosine phosphatase, receptor type, N severity ISO RGD PMID:19513530 RGD:2313594 NCBI chr 9:76,741,010...76,756,704
Ensembl chr 9:76,741,016...76,756,190
JBrowse link
G Ptpru protein tyrosine phosphatase, receptor type, U IEP protein:decreased expression:glomerulus RGD PMID:16539708 RGD:1642656 NCBI chr 5:143,950,542...144,024,791
Ensembl chr 5:143,950,965...144,024,768
JBrowse link
G Pygm glycogen phosphorylase, muscle associated IDA protein:increased expression:sarcoplasmic reticulum RGD PMID:11692172 RGD:1599897 NCBI chr 1:203,690,550...203,705,369
Ensembl chr 1:203,690,533...203,705,368
JBrowse link
G Qdpr quinoid dihydropteridine reductase IEP protein:decreased activity:brain (rat) RGD PMID:2758679 RGD:5128601 NCBI chr14:65,670,251...65,683,853
Ensembl chr14:65,670,131...65,683,854
JBrowse link
G Ramp2 receptor activity modifying protein 2 IEP mRNA:increased expression:kidney RGD PMID:14717924 RGD:1642701 NCBI chr10:86,187,366...86,190,692
Ensembl chr10:86,188,812...86,231,829
JBrowse link
G Rap1b RAP1B, member of RAS oncogene family IEP protein:increased expression:renal glomerulus (rat) RGD PMID:12196513 RGD:10041023 NCBI chr 7:53,423,039...53,456,388
Ensembl chr 7:53,423,130...53,456,370
JBrowse link
G Rasgrf1 RAS protein-specific guanine nucleotide-releasing factor 1 IEP protein:decreased expression:brain, membrane (rat) RGD PMID:19002579 RGD:10003129 NCBI chr 8:90,445,154...90,574,274
Ensembl chr 8:90,445,154...90,574,269
JBrowse link
G Reg1a regenerating family member 1 alpha treatment IDA
IEP
protein:increased expression:pancreas, islet cell (rat) RGD PMID:8170952 PMID:8574288 RGD:9850123, RGD:9850143 NCBI chr 4:110,892,451...110,895,115
Ensembl chr 4:110,892,453...110,895,570
JBrowse link
G Reg3b regenerating family member 3 beta susceptibility ISO RGD PMID:21245462 RGD:9831432 NCBI chr 4:110,861,775...110,865,015
Ensembl chr 4:110,861,775...110,865,015
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit IEP
ISO
CTD Direct Evidence: marker/mechanism
protein:increased expression:nucleus, skeletal muscle, liver
CTD
RGD
PMID:22138235 PMID:18633731 PMID:18500427 RGD:2298775, RGD:2298780 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Ren renin ISO CTD Direct Evidence: marker/mechanism CTD PMID:18829990 NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489
JBrowse link
G Rgn regucalcin IEP protein:decreased expression:liver RGD PMID:9062895 RGD:9590177 NCBI chr  X:1,619,030...1,634,456
Ensembl chr  X:1,619,032...1,634,450
JBrowse link
G Rhoa ras homolog family member A IDA RGD PMID:17589825 RGD:1642825 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link
G Rpe65 retinoid isomerohydrolase RPE65 IEP mRNA:decreased expression:retina (rat) RGD PMID:21862641 RGD:9585653 NCBI chr 2:248,766,497...248,798,403
Ensembl chr 2:248,766,612...248,798,403
JBrowse link
G Ryr2 ryanodine receptor 2 IDA RGD PMID:17027851 RGD:1599247 NCBI chr17:58,389,925...58,975,641
Ensembl chr17:58,389,925...58,975,142
JBrowse link
G S100a6 S100 calcium binding protein A6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16123366 NCBI chr 2:176,100,619...176,102,181
Ensembl chr 2:176,100,899...176,102,180
JBrowse link
G S100b S100 calcium binding protein B IEP protein:increased expression:cerebellum, cerebral cortex, hippocampus
protein:altered expression:hippocampus, astrocyte
RGD PMID:14583344 PMID:18708122 RGD:5508821, RGD:5508836 NCBI chr20:12,372,866...12,381,619
Ensembl chr20:12,372,881...12,394,743
JBrowse link
G S1pr2 sphingosine-1-phosphate receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22406263 NCBI chr 8:19,503,276...19,514,169
Ensembl chr 8:19,502,627...19,523,574
JBrowse link
G S1pr4 sphingosine-1-phosphate receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22406263 NCBI chr 7:8,207,767...8,210,043
Ensembl chr 7:8,208,098...8,211,893
JBrowse link
G S1pr5 sphingosine-1-phosphate receptor 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22406263 NCBI chr 8:19,786,676...19,791,862
Ensembl chr 8:19,786,663...19,791,795
JBrowse link
G Scap SREBF chaperone IEP RGD PMID:20973890 RGD:5490977 NCBI chr 8:110,306,031...110,360,677
Ensembl chr 8:110,306,031...110,360,666
JBrowse link
G Scp2 sterol carrier protein 2 treatment IEP RGD PMID:7628371 RGD:9850252 NCBI chr 5:122,806,949...122,881,259
Ensembl chr 5:122,776,549...122,881,287
JBrowse link
G Serpinc1 serpin family C member 1 treatment IDA
IEP
RGD PMID:22309505 PMID:24671746 RGD:11035271, RGD:11035293 NCBI chr13:73,257,208...73,271,476
Ensembl chr13:73,257,179...73,284,293
JBrowse link
G Serpine1 serpin family E member 1 ISO protein:increased expression:heart (mouse)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:21757225 PMID:20630999 RGD:8547862 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Serpinf1 serpin family F member 1 IEP protein:decreased expression:platelet RGD PMID:19237211 RGD:2312338 NCBI chr10:60,250,198...60,262,593
Ensembl chr10:60,249,708...60,262,646
JBrowse link
G Si sucrase-isomaltase IEP protein:increased expression:small intestine mucosa RGD PMID:12940455 RGD:1625543 NCBI chr 2:157,505,893...157,586,228
Ensembl chr 2:157,506,342...157,585,260
JBrowse link
G Sirt1 sirtuin 1 treatment IEP
ISO
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:23090186 PMID:23792339 PMID:22179968 RGD:9586012 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Slc22a1 solute carrier family 22 member 1 IDA RGD PMID:14718608 RGD:2317435 NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678
JBrowse link
G Slc22a2 solute carrier family 22 member 2 IEP protein:decreased expression:kidney RGD PMID:19356064 RGD:2312728 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link
G Slc28a2 solute carrier family 28 member 2 IDA RGD PMID:16014043 RGD:2317455 NCBI chr 3:109,324,815...109,387,702
Ensembl chr 3:109,366,996...109,387,702
JBrowse link
G Slc28a3 solute carrier family 28 member 3 IDA RGD PMID:16014043 RGD:2317455 NCBI chr17:6,062,563...6,112,965
Ensembl chr17:6,062,549...6,114,038
JBrowse link
G Slc29a1 solute carrier family 29 member 1 IEP mRNA:decreased expression:cardiac muscle cell RGD PMID:16873415 RGD:2316941 NCBI chr 9:15,399,661...15,414,203
Ensembl chr 9:15,399,612...15,414,203
JBrowse link
G Slc2a1 solute carrier family 2 member 1 treatment IEP mRNA, protein:decreased expression:brain RGD PMID:17935675 PMID:8345816 RGD:2313617, RGD:12879858 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
JBrowse link
G Slc2a2 solute carrier family 2 member 2 IEP
ISO
mRNA:increased expression:kidney
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:16123366 PMID:19433262 RGD:2312358 NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933
JBrowse link
G Slc2a3 solute carrier family 2 member 3 IEP mRNA, protein:decreased expression:brain RGD PMID:17935675 RGD:2313617 NCBI chr 4:155,960,944...156,026,000
Ensembl chr 4:155,960,946...156,025,472
JBrowse link
G Slc2a4 solute carrier family 2 member 4 IEP
ISO
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:11947963 PMID:14563825 PMID:18266981 PMID:22138235 PMID:19252289 RGD:2313621 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
JBrowse link
G Slc37a4 solute carrier family 37 member 4 IEP protein:increased expression:liver RGD PMID:10567346 RGD:1625641 NCBI chr 8:44,723,216...44,729,301
Ensembl chr 8:44,723,339...44,729,301
JBrowse link
G Slc38a2 solute carrier family 38, member 2 IEP RGD PMID:11798158 RGD:9999213 NCBI chr 7:127,851,267...127,863,482
Ensembl chr 7:127,851,267...127,863,436
JBrowse link
G Slc8a1 solute carrier family 8 member A1 IEP mRNA, protein:decreased expression:cardiac muscle cell RGD PMID:10944172 RGD:1642714 NCBI chr 6:13,194,609...13,547,369
Ensembl chr 6:13,194,662...13,535,628
JBrowse link
G Slc9a1 solute carrier family 9 member A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20003708 NCBI chr 5:145,576,341...145,629,630
Ensembl chr 5:145,576,334...145,629,624
JBrowse link
G Slc9a3 solute carrier family 9 member A3 IDA
ISO
protein:increased activity:kidney cortex
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:20003708 PMID:16244498 RGD:1625673 NCBI chr 1:29,124,633...29,167,912
Ensembl chr 1:29,124,674...29,167,417
JBrowse link
G Smad1 SMAD family member 1 severity IEP protein:increased expression:glomerulus, urine RGD PMID:16482100 RGD:1643228 NCBI chr19:28,513,130...28,573,665
Ensembl chr19:28,513,131...28,573,651
JBrowse link
G Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 treatment IEP RGD PMID:23853776 RGD:9586347 NCBI chr 8:20,167,717...20,258,975
Ensembl chr 8:20,167,717...20,258,975
JBrowse link
G Smpd1 sphingomyelin phosphodiesterase 1 IDA protein:decreased expression:gastrocnemius RGD PMID:14983401 RGD:1601347 NCBI chr 1:159,892,946...159,896,789
Ensembl chr 1:159,892,859...159,896,794
JBrowse link
G Snap25 synaptosome associated protein 25 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16123366 NCBI chr 3:124,041,898...124,123,761
Ensembl chr 3:124,041,898...124,123,760
JBrowse link
G Soat2 sterol O-acyltransferase 2 IDA RGD PMID:15242859 RGD:1581191 NCBI chr 7:133,281,818...133,294,915
Ensembl chr 7:133,281,818...133,294,915
JBrowse link
G Socs3 suppressor of cytokine signaling 3 susceptibility IEP
ISO
mRNA, protein:increased expression:retina RGD PMID:18356406 PMID:17562326 RGD:2298911, RGD:2313787 NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787
JBrowse link
G Sod1 superoxide dismutase 1 IEP
ISO
protein:increased expression:hippocampus (rat)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:23090186 PMID:20924670 RGD:8655956 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 IEP
ISO
protein:increased activity:testes
CTD Direct Evidence: marker/mechanism|therapeutic
CTD
RGD
PMID:15855331 PMID:23090186 PMID:19891634 RGD:2317382 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sord sorbitol dehydrogenase IEP protein:increased expression:liver RGD PMID:15064821 RGD:1601360 NCBI chr 3:109,184,697...109,216,133
Ensembl chr 3:109,184,676...109,216,133
JBrowse link
G Sox2 SRY-box transcription factor 2 IEP RGD PMID:23828673 RGD:8661677 NCBI chr 2:117,536,929...117,539,338
Ensembl chr 2:117,536,929...117,539,338
JBrowse link
G Spp1 secreted phosphoprotein 1 IDA RGD PMID:16528250 RGD:1581322 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 IEP
ISO
mRNA, protein:increased expression:renal proximal tubule, epithelial cell
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:10900012 PMID:23090186 PMID:19048273 RGD:2308804 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Sstr1 somatostatin receptor 1 IEP RGD PMID:7956902 RGD:2325008 NCBI chr 6:75,832,292...75,836,806
Ensembl chr 6:75,832,530...75,836,802
JBrowse link
G Sstr2 somatostatin receptor 2 IEP RGD PMID:7956902 RGD:2325008 NCBI chr10:98,664,204...98,671,370
Ensembl chr10:98,664,216...98,674,351
JBrowse link
G Sstr3 somatostatin receptor 3 IEP RGD PMID:7956902 RGD:2325008 NCBI chr 7:110,092,563...110,109,043
Ensembl chr 7:110,092,575...110,099,769
JBrowse link
G Sstr5 somatostatin receptor 5 IEP RGD PMID:7956902 RGD:2325008 NCBI chr10:14,506,868...14,512,946
Ensembl chr10:14,506,868...14,512,946
JBrowse link
G Star steroidogenic acute regulatory protein IEP mRNA:decreased expression:sciatic nerve (rat) RGD PMID:20826654 RGD:4145530 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
JBrowse link
G Stat1 signal transducer and activator of transcription 1 IDA protein:increased tyrosine phosphorylation:glomerulus RGD PMID:14678947 RGD:1600105 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540
JBrowse link
G Stat3 signal transducer and activator of transcription 3 IEP
ISO
protein:increased tyrosine phosphorylation:aorta endothelium RGD PMID:18230613 PMID:22660795 RGD:2291921, RGD:8694292 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Stat4 signal transducer and activator of transcription 4 ISO RGD PMID:10553062 RGD:7207889 NCBI chr 9:49,472,660...49,588,540
Ensembl chr 9:49,419,340...49,588,540
JBrowse link
G Stat5b signal transducer and activator of transcription 5B IMP RGD PMID:17003334 RGD:2291940 NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668
JBrowse link
G Sts steroid sulfatase ISO CTD Direct Evidence: therapeutic CTD PMID:24497646 NCBI chr  X:42,225,131...42,233,403
Ensembl chr  X:42,225,372...42,233,402
JBrowse link
G Tert telomerase reverse transcriptase IEP RGD PMID:20031167 RGD:2316310 NCBI chr 1:29,637,213...29,659,509
Ensembl chr 1:29,637,506...29,659,561
JBrowse link
G Tf transferrin IEP RGD PMID:17081048 RGD:1601532 NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511
JBrowse link
G Tgfb1 transforming growth factor, beta 1 IEP
ISO
protein:increased expression:urine
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:17177138 PMID:23090186 PMID:15855808 RGD:1601583 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfb2 transforming growth factor, beta 2 IEP protein:increased expression:parotid gland RGD PMID:17574405 RGD:2302087 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
JBrowse link
G Th tyrosine hydroxylase IEP protein:increased expression:seminal vesicle RGD PMID:17151307 RGD:1601629 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
JBrowse link
G Thbs1 thrombospondin 1 IMP RGD PMID:17640965 RGD:2317942 NCBI chr 3:105,056,286...105,071,445
Ensembl chr 3:105,056,292...105,071,440
JBrowse link
G Timm44 translocase of inner mitochondrial membrane 44 IEP protein:decreased expression:retina RGD PMID:23255365 RGD:13463486 NCBI chr12:2,612,581...2,629,374
Ensembl chr12:2,612,581...2,629,351
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 IEP
ISO
protein:increased expression:kidney
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:21963884 PMID:17569353 PMID:17192464 RGD:2290354, RGD:2312467 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21963884 NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611
JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 ISO mRNA:increased expression:glomerulus RGD PMID:8840279 RGD:2312482 NCBI chr 7:17,520,827...17,571,871
Ensembl chr 7:17,521,919...17,571,839
JBrowse link
G Tjp1 tight junction protein 1 IEP protein:decreased expression:glomerulus RGD PMID:16567508 RGD:2325150 NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432
JBrowse link
G Tlr2 toll-like receptor 2 IEP
ISO
RGD PMID:16740310 PMID:17707128 RGD:2312491, RGD:2312684 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630
JBrowse link
G Tlr4 toll-like receptor 4 IEP RGD PMID:16740310 RGD:2312491 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tnc tenascin C IEP RGD PMID:17999372 RGD:4889609 NCBI chr 5:77,375,851...77,460,712
Ensembl chr 5:77,375,851...77,460,624
JBrowse link
G Tnf tumor necrosis factor treatment IEP
ISO
protein:increased expression:heart
CTD Direct Evidence: marker/mechanism
protein:increased expression:liver
CTD
RGD
PMID:12123627 PMID:12193562 PMID:19478208 PMID:20388520 PMID:22138235 More... RGD:4142788, RGD:2312478, RGD:10450575, RGD:5131250 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A IEP
ISO
protein:increased expression:liver (rat)
CTD Direct Evidence: therapeutic
CTD
RGD
PMID:12193562 PMID:21481476 RGD:5131250 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B ISO human protein in rat model RGD PMID:21481476 RGD:5131250 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206
JBrowse link
G Tnfsf10 TNF superfamily member 10 ISO
IEP
RGD PMID:12577054 PMID:19572802 PMID:18649770 RGD:2312744, RGD:2312737, RGD:2312738 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
JBrowse link
G Tomm40 translocase of outer mitochondrial membrane 40 IEP protein:decreased expression:retina RGD PMID:23255365 RGD:13463486 NCBI chr 1:79,358,781...79,370,976
Ensembl chr 1:79,358,786...79,370,915
JBrowse link
G Tomm70 translocase of outer mitochondrial membrane 70 IEP protein:decreased expression:retina RGD PMID:23255365 RGD:13463486 NCBI chr11:43,378,719...43,417,166
Ensembl chr11:43,377,216...43,417,202
JBrowse link
G Tp53 tumor protein p53 IEP
ISO
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:21078376 PMID:23792339 PMID:24828139 RGD:8662307 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tp63 tumor protein p63 IEP protein:increased expression:prostate gland RGD PMID:20041964 RGD:11568648 NCBI chr11:74,838,858...75,049,764
Ensembl chr11:74,838,859...75,049,398
JBrowse link
G Tpi1 triosephosphate isomerase 1 IEP protein:decreased expression:retina RGD PMID:17465459 RGD:5147874 NCBI chr 4:157,615,283...157,618,813
Ensembl chr 4:157,615,386...157,619,541
JBrowse link
G Trex2 three prime repair exonuclease 2 IEP RGD PMID:20973890 RGD:5490977 NCBI chr  X:151,151,862...151,153,470
Ensembl chr  X:151,151,864...151,153,479
JBrowse link
G Trpc1 transient receptor potential cation channel, subfamily C, member 1 IEP mRNA:decreased expression:kidney, liver RGD PMID:18184923 RGD:2301838 NCBI chr 8:96,263,322...96,314,197
Ensembl chr 8:96,263,329...96,314,276
JBrowse link
G Tsc2 TSC complex subunit 2 IEP protein:increased threonine phosphorylation:cortex of kidney RGD PMID:18599524 RGD:8657153 NCBI chr10:13,621,135...13,655,773
Ensembl chr10:13,621,136...13,655,951
JBrowse link
G Twnk twinkle mtDNA helicase IEP
ISO
mRNA,protein:decreased expression:retina,mitochondrion: RGD PMID:22743328 PMID:22229649 RGD:8694093, RGD:8694187 NCBI chr 1:243,867,568...243,874,802
Ensembl chr 1:243,868,330...243,874,802
JBrowse link
G Txn1 thioredoxin 1 IEP mRNA:altered expression:myocardium (rat) RGD PMID:20571744 RGD:5133714 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
JBrowse link
G Txn2 thioredoxin 2 IEP mRNA:increased expression:glomerulus
mRNA:altered expression:myocardium (rat)
RGD PMID:15039483 PMID:20571744 RGD:2306161, RGD:5133714 NCBI chr 7:109,496,772...109,510,378
Ensembl chr 7:109,496,761...109,510,359
JBrowse link
G Txnip thioredoxin interacting protein IEP protein:increased expression:kidney RGD PMID:17675577 RGD:1642749 NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
JBrowse link
G Txnrd1 thioredoxin reductase 1 IEP mRNA:altered expression:myocardium (rat) RGD PMID:20571744 RGD:5133714 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
JBrowse link
G Txnrd2 thioredoxin reductase 2 IEP mRNA:altered expression:myocardium (rat) RGD PMID:20571744 RGD:5133714 NCBI chr11:82,519,996...82,568,156
Ensembl chr11:82,519,999...82,568,156
JBrowse link
G Uba52 ubiquitin A-52 residue ribosomal protein fusion product 1 ISO mRNA:increased expression:kidney (mouse) RGD PMID:12171997 RGD:11352735 NCBI chr16:18,918,614...18,920,807
Ensembl chr16:18,900,616...18,920,807
JBrowse link
G Uchl5 ubiquitin C-terminal hydrolase L5 IEP RGD PMID:23500140 RGD:9588239 NCBI chr13:55,520,722...55,556,503
Ensembl chr13:55,520,729...55,556,502
JBrowse link
G Uck2 uridine-cytidine kinase 2 IEP protein:decreased activity:heart, skeletal muscle RGD PMID:221781 RGD:2317214 NCBI chr13:79,380,807...79,438,352
Ensembl chr13:79,383,846...79,438,352
JBrowse link
G Ucp2 uncoupling protein 2 IEP
ISO
protein:increased expression:kidney
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:14563825 PMID:16123366 PMID:19227473 RGD:2313501 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
JBrowse link
G Ucp3 uncoupling protein 3 susceptibility IEP
ISO
mRNA:increased expression:skeletal muscle RGD PMID:10868941 PMID:12079841 RGD:2313524, RGD:2313520 NCBI chr 1:154,815,777...154,828,764
Ensembl chr 1:154,815,777...154,828,762
JBrowse link
G Ugt2b17 UDP glucuronosyltransferase family 2 member B17 IEP mRNA:increased expression:liver RGD PMID:20487213 RGD:11541075 NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986
JBrowse link
G Umod uromodulin IEP protein:increased expression:urine RGD PMID:10925066 RGD:2324705 NCBI chr 1:173,816,341...173,829,681
Ensembl chr 1:173,816,339...173,830,302
JBrowse link
G Umps uridine monophosphate synthetase IEP protein:decreased activity:liver (rat)
protein:decreased activity:mammary gland (rat)
RGD PMID:3907307 PMID:1476792 RGD:5132278, RGD:5132591 NCBI chr11:66,806,107...66,816,520
Ensembl chr11:66,806,045...66,821,903
JBrowse link
G Uprt uracil phosphoribosyltransferase homolog IEP protein:decreased activity:mammary gland (rat) RGD PMID:1476792 RGD:5132591 NCBI chr  X:69,516,573...69,546,811
Ensembl chr  X:69,516,738...69,546,797
JBrowse link
G Uts2r urotensin 2 receptor IMP RGD PMID:16267137 RGD:2306839 NCBI chr10:106,438,092...106,439,252
Ensembl chr10:106,438,092...106,439,252
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 IEP
ISO
mRNA, protein:increased expression:kidney
mRNA:increased expression:aorta
RGD PMID:18983856 PMID:18093596 RGD:2312764, RGD:2306988 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
G Vdac1 voltage-dependent anion channel 1 IEP protein:increased expression:kidney RGD PMID:19634143 RGD:10003054 NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640
JBrowse link
G Vegfa vascular endothelial growth factor A IEP
ISO
IDA
mRNA:decreased expression:heart
CTD Direct Evidence: marker/mechanism
mRNA:decreased expression:skeletal muscle
CTD
RGD
PMID:22191573 PMID:16741021 PMID:19934008 PMID:16816123 RGD:2313724, RGD:7421582, RGD:2313725 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Vegfb vascular endothelial growth factor B ISO mRNA:decreased expression:skeletal muscle RGD PMID:16816123 RGD:2313725 NCBI chr 1:204,172,297...204,178,046
Ensembl chr 1:204,172,225...204,177,944
JBrowse link
G Vip vasoactive intestinal peptide ISO RGD PMID:21129425 RGD:5685622 NCBI chr 1:42,064,878...42,073,219
Ensembl chr 1:42,065,120...42,073,216
JBrowse link
G Vipr1 vasoactive intestinal peptide receptor 1 ISO RGD PMID:21129425 RGD:5685622 NCBI chr 8:121,303,739...121,339,587
Ensembl chr 8:121,310,248...121,339,585
JBrowse link
G Vldlr very low density lipoprotein receptor IEP protein:decreased expression:heart, skeletal muscle RGD PMID:15878964 RGD:1625575 NCBI chr 1:224,813,539...224,850,400
Ensembl chr 1:224,814,377...224,845,920
JBrowse link
G Vwf von Willebrand factor IEP protein:increased expression:plasma RGD PMID:17546272 RGD:1625712 NCBI chr 4:158,360,152...158,491,539
Ensembl chr 4:158,360,152...158,491,539
JBrowse link
G Wdr35 WD repeat domain 35 IEP mRNA:increased expression:kidney (rat) RGD PMID:20224876 RGD:11553923 NCBI chr 6:31,771,315...31,831,450
Ensembl chr 6:31,771,360...31,831,029
JBrowse link
G Xdh xanthine dehydrogenase IEP protein:increased expression:brain, heart, kidney RGD PMID:14532905 RGD:1304441 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268
JBrowse link
G Ywhah tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta ISO CTD Direct Evidence: therapeutic CTD PMID:18342293 NCBI chr14:77,696,332...77,705,715
Ensembl chr14:77,696,333...77,705,741
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 17427
    Animal Diseases 1675
      Animal Disease Models 1623
        Experimental Diabetes Mellitus 589
Path 2
Term Annotations click to browse term
  disease 17427
    Nutritional and Metabolic Diseases 5589
      disease of metabolism 5589
        acquired metabolic disease 2906
          carbohydrate metabolism disease 1801
            glucose metabolism disease 1801
              diabetes mellitus 1407
                Experimental Diabetes Mellitus 589
paths to the root