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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Splenic Neoplasms
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Accession:DOID:9005343 term browser browse the term
Definition:Tumors or cancer of the SPLEEN.
Synonyms:exact_synonym: spleen neoplasm;   spleen neoplasms;   splenic neoplasm
 primary_id: MESH:D013160

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Splenic Neoplasms term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hras HRas proto-oncogene, GTPase ISO CTD Direct Evidence: marker/mechanism CTD PMID:26558449 NCBI chrNW_004936888:375,372...378,125
Ensembl chrNW_004936888:375,377...377,958 		JBrowse link
spleen cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ramp2 receptor activity modifying protein 2 ameliorates ISO RGD PMID:31754214 RGD:152985691 NCBI chrNW_004936490:17,479,899...17,481,788
Ensembl chrNW_004936490:17,479,650...17,482,716 		JBrowse link
splenic marginal zone lymphoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd79b CD79b molecule ISO protein:decreased expression:blood, B cell (human) RGD PMID:10329919 RGD:11531139 NCBI chrNW_004936541:4,534,233...4,537,448
Ensembl chrNW_004936541:4,534,246...4,537,590 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16443
    disease of cellular proliferation 6794
      Neoplasms by Site 6299
        Splenic Neoplasms 3
          Littoral Cell Angioma of the Spleen 0
          spleen cancer + 2
Path 2
Term Annotations click to browse term
  disease 16443
    disease of anatomical entity 14067
      Immune & Inflammatory Diseases 4674
        immune system disease 4068
          lymphatic system disease 1483
            splenic disease 139
              Splenic Neoplasms 3
                Littoral Cell Angioma of the Spleen 0
                spleen cancer + 2
paths to the root